Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.326
Biljana Prgova Veljanova, Andrea Nancheva Bogoevska, Gordana Bozinovska Beaka, A. Gjoreski, Jasminka Nancheva
Melanoma is an aggressive malignant tumor that originates from melanocytes and most commonly occurs on the skin. Dominantly metastasize to regional lymph nodes, in the brain and lungs and rarely in the gastrointestinal (GI) system. The aim of this report is to present a rare case of metastasis of cutaneous malignant melanoma in the gallbladder, discovered 10 months after excision of the primary melanoma of the skin. A 45-year-old patient was hospitalized in our hospital due to abdominal pain in right upper quadrant and nausea lasting for 7 days. An intraluminal substrate was found in the gallbladder with computed tomography and later a CT guied biopsy was performed on it, thus proving a metastatic deposit of primary malignant melanoma. Metastatic deposits in the gallbladder are extremely rare finding, and 238 cases have been described in the literature.
{"title":"METASTATIC CUTANEUS MELANOMA OF THE GALLBLADDER-CASE REPORT","authors":"Biljana Prgova Veljanova, Andrea Nancheva Bogoevska, Gordana Bozinovska Beaka, A. Gjoreski, Jasminka Nancheva","doi":"10.24125/SANAMED.V14I2.326","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.326","url":null,"abstract":"Melanoma is an aggressive malignant tumor that originates from melanocytes and most commonly occurs on the skin. Dominantly metastasize to regional lymph nodes, in the brain and lungs and rarely in the gastrointestinal (GI) system. The aim of this report is to present a rare case of metastasis of cutaneous malignant melanoma in the gallbladder, discovered 10 months after excision of the primary melanoma of the skin. A 45-year-old patient was hospitalized in our hospital due to abdominal pain in right upper quadrant and nausea lasting for 7 days. An intraluminal substrate was found in the gallbladder with computed tomography and later a CT guied biopsy was performed on it, thus proving a metastatic deposit of primary malignant melanoma. Metastatic deposits in the gallbladder are extremely rare finding, and 238 cases have been described in the literature.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42661259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.336
Israa F. Mosa, M. Youssef, T. Shalaby, O. Mosa
Silver nanoparticles (AgNPs) are being used extensively for biomedical purposes regarding to their broad antimicrobial activity, however their toxicity has been addressed in only few studies. In the present study, we aimed to prepare and characterize AgNPs, investigate their adverse effect on liver and kidney functions, and also elucidate the hepato-nephro protective ability of tannic acid in male rats. The obtained results showed that AgNPs caused oxidative stress throughout the induction of thiobarbituric acid-reactive substances (TBARS) and the reduction of the activities of antioxidant enzymes (GST, SOD, CAT, GPx) and the levels of glutathione. Hepatic markers enzymes (AST, ALT, ALP, ACP, LDH and GGT), total bilirubin, urea, creatinine and lipid profile were increased, while hematological parameters were decreased. Histopathological investigations indicated marked degeneration of hepatocytes, endothelial cells of renal which with its role has confirmed the hepatotoxicity and nephrotoxicity induced by AgNPs. The presence of tannic acid along with AgNPs showed obvious improvements in the injured liver and kidney tissues. The protective effect of tannic acid against the toxicity of AgNPs might be due to its antioxidant properties and scavenging abilities against active free radicals.
{"title":"THE PROTECTIVE ROLE OF TANNIC ACID AGAINST POSSIBLE HEPATO-NEPHROTOXICITY INDUCED BY SILVER NANOPARTICLES ON MALE RATS","authors":"Israa F. Mosa, M. Youssef, T. Shalaby, O. Mosa","doi":"10.24125/SANAMED.V14I2.336","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.336","url":null,"abstract":"Silver nanoparticles (AgNPs) are being used extensively for biomedical purposes regarding to their broad antimicrobial activity, however their toxicity has been addressed in only few studies. In the present study, we aimed to prepare and characterize AgNPs, investigate their adverse effect on liver and kidney functions, and also elucidate the hepato-nephro protective ability of tannic acid in male rats. The obtained results showed that AgNPs caused oxidative stress throughout the induction of thiobarbituric acid-reactive substances (TBARS) and the reduction of the activities of antioxidant enzymes (GST, SOD, CAT, GPx) and the levels of glutathione. Hepatic markers enzymes (AST, ALT, ALP, ACP, LDH and GGT), total bilirubin, urea, creatinine and lipid profile were increased, while hematological parameters were decreased. Histopathological investigations indicated marked degeneration of hepatocytes, endothelial cells of renal which with its role has confirmed the hepatotoxicity and nephrotoxicity induced by AgNPs. The presence of tannic acid along with AgNPs showed obvious improvements in the injured liver and kidney tissues. The protective effect of tannic acid against the toxicity of AgNPs might be due to its antioxidant properties and scavenging abilities against active free radicals.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44695764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.311
Bahtiyar Muhammedoğlu, S. Topuz, M. Saraçoğlu, Suleyman Koktas, Mehmeti Ejup, Turgay Kara
Rotation anomalies are usually anomalies seen in children. It is a rare condition in adults. In this article, 4 cases are presented. In the first case, reverse rotation anomaly and appendicitis perforation were detected in a patient who had laparotomy at the age of 22 with acute abdomen. It is a unique condition that the patient had a history of previous appendectomy. Ladd band may be the cause of acute abdomen due to ileus. The patient in our second case presented a concurrent biliary stone and malrotation with Ladd band. In addition, two elderly patients who underwent hemicolectomy due to intestinal ileus caused by malrotation were presented with literature review.
{"title":"UNCOMMON INTESTINAL MALROTATION IN ADULT PATIENTS- PRESENTATION OF 4 CASES","authors":"Bahtiyar Muhammedoğlu, S. Topuz, M. Saraçoğlu, Suleyman Koktas, Mehmeti Ejup, Turgay Kara","doi":"10.24125/SANAMED.V14I2.311","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.311","url":null,"abstract":"Rotation anomalies are usually anomalies seen in children. It is a rare condition in adults. In this article, 4 cases are presented. In the first case, reverse rotation anomaly and appendicitis perforation were detected in a patient who had laparotomy at the age of 22 with acute abdomen. It is a unique condition that the patient had a history of previous appendectomy. Ladd band may be the cause of acute abdomen due to ileus. The patient in our second case presented a concurrent biliary stone and malrotation with Ladd band. In addition, two elderly patients who underwent hemicolectomy due to intestinal ileus caused by malrotation were presented with literature review.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42132479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.308
Aydın Yildiz, A. Comez
Purpose: To evaluate the incidence of posterior capsular opacification after cataract surgery in patients on hemodialysis. Patients and Methods: Fifty patients on hemodialysis undergoing cataract surgery and 50 patients undergoing cataract surgery in a similar age group without any systemic disease were compared retrospectively. All patients underwent uneventful phacoemulsification surgery. Hydrophilic monoblock, sharp-edged acrylic intraocular lens (Spectrafold™, Gujarat, India) was used. A complete ophthalmological examination was performed on the patients who were evaluated at the postoperative 12th month follow-up examination. Posterior capsular opacification was evaluated by the retroillumination method. According to the reflection from retroillumination, cases with posterior capsular opacification were divided into three groups as mild, moderate and severe. Results: Age groups and male to female ratios were similar. Mean best corrected visual acuity (BCVA) was 0.23 in the hemodialysis group and 0.22 in the control group, preoperatively. At the end of the first year, the mean BCVA was 0.88 in the hemodialysis group and 0.94 in the control group. In the hemodialysis group, the percentage of posterior capsular opacification was 60% and was 14% in the control group; this difference was statistically significant (p <0.05). While the capsular opacity was mild in all 7 patients in the control group, itwas mild in 19 patients, moderate in 8 and severe in 3 patients in the hemodialysis group. Conclusion: The incidence of posterior capsular opacification after uneventful cataract surgery is found to be higher in patients on hemodialysis than in the normal population.
{"title":"INCIDENCE OF POSTERIOR CAPSULAR OPACIFICATION AFTER UNEVENTFUL CATARACT SURGERY IN PATIENTS ON HEMODIALYSIS","authors":"Aydın Yildiz, A. Comez","doi":"10.24125/SANAMED.V14I2.308","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.308","url":null,"abstract":"Purpose: To evaluate the incidence of posterior capsular opacification after cataract surgery in patients on hemodialysis. Patients and Methods: Fifty patients on hemodialysis undergoing cataract surgery and 50 patients undergoing cataract surgery in a similar age group without any systemic disease were compared retrospectively. All patients underwent uneventful phacoemulsification surgery. Hydrophilic monoblock, sharp-edged acrylic intraocular lens (Spectrafold™, Gujarat, India) was used. A complete ophthalmological examination was performed on the patients who were evaluated at the postoperative 12th month follow-up examination. Posterior capsular opacification was evaluated by the retroillumination method. According to the reflection from retroillumination, cases with posterior capsular opacification were divided into three groups as mild, moderate and severe. Results: Age groups and male to female ratios were similar. Mean best corrected visual acuity (BCVA) was 0.23 in the hemodialysis group and 0.22 in the control group, preoperatively. At the end of the first year, the mean BCVA was 0.88 in the hemodialysis group and 0.94 in the control group. In the hemodialysis group, the percentage of posterior capsular opacification was 60% and was 14% in the control group; this difference was statistically significant (p <0.05). While the capsular opacity was mild in all 7 patients in the control group, itwas mild in 19 patients, moderate in 8 and severe in 3 patients in the hemodialysis group. Conclusion: The incidence of posterior capsular opacification after uneventful cataract surgery is found to be higher in patients on hemodialysis than in the normal population.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47405061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.335
B. Lazovic, Ivan Blazic, Džemail Detanac, R. Milić, S. Šarac, Dzenana A. Detanac, V. Žugić
Introduction: Although pleural effusion is a common clinical manifestation, the differential diagnosis of the cause of the pleural effusion is often challenging, especially in the early differentiation of tuberculous pleurisy (TP) from other pleural effusion. Case report: We present a previously healthy man who had no contagious or TB contact but developed massive tuberculous pleural effusion which eventually was unexpected tuberculous. He started with therapy per protocol and feeling well. The purpose of this case and review of literature was to remind the physicians that tuberculosis is not a sickening illness, but on the contrary, it is in the expansion. Discussion: When a patient presents with new pleural effusion, the diagnosis of tuberculous pleuritis should be considered. The patient is at great risk for developing pulmonary or extra pulmonary TB if the diagnosis is not made properly. Between 3% and 25% of patients with TB will have TB pleuritic or more in immunocompromised patients.The treatment for TB pleuritis is the same as that for pulmonary TB. Conclusion: The gold standard for the diagnosis of tuberculous pleural effusion remains the detection of Mycobacterium tuberculosis in pleural fluid, or pleural biopsy specimens, either by microscopy and/or culture, or the histological demonstration of caseating granulomas in the pleura along with acid fast bacilli.
{"title":"TUBERCULOUS PLEURAL EFFUSION IN THE PREVIOUSLY HEALTHY MAN-CASE REPORT AND REVIEW OF THE LITERATURE","authors":"B. Lazovic, Ivan Blazic, Džemail Detanac, R. Milić, S. Šarac, Dzenana A. Detanac, V. Žugić","doi":"10.24125/SANAMED.V14I2.335","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.335","url":null,"abstract":"Introduction: Although pleural effusion is a common clinical manifestation, the differential diagnosis of the cause of the pleural effusion is often challenging, especially in the early differentiation of tuberculous pleurisy (TP) from other pleural effusion. Case report: We present a previously healthy man who had no contagious or TB contact but developed massive tuberculous pleural effusion which eventually was unexpected tuberculous. He started with therapy per protocol and feeling well. The purpose of this case and review of literature was to remind the physicians that tuberculosis is not a sickening illness, but on the contrary, it is in the expansion. Discussion: When a patient presents with new pleural effusion, the diagnosis of tuberculous pleuritis should be considered. The patient is at great risk for developing pulmonary or extra pulmonary TB if the diagnosis is not made properly. Between 3% and 25% of patients with TB will have TB pleuritic or more in immunocompromised patients.The treatment for TB pleuritis is the same as that for pulmonary TB. Conclusion: The gold standard for the diagnosis of tuberculous pleural effusion remains the detection of Mycobacterium tuberculosis in pleural fluid, or pleural biopsy specimens, either by microscopy and/or culture, or the histological demonstration of caseating granulomas in the pleura along with acid fast bacilli.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45924145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.316
F. Fehintola, A. Fehintola, O. Ogundele, C. Adegbenro, S. olowookere, O. Afolabi
Introduction: Cervical cancer is the second most common cancer in women worldwide and in Nigeria. Human papilloma virus (HPV), has been implicated as the causative agent of cervical cancer. The fact that HPV vaccination can prevent the occurrence of this deadly cancer is well established. Though the vaccine has been licensed in Nigeria since 2008 with widespread availability, it is yet to be included in National immunization program in Nigeria. This study aimed to assess the predictors and acceptability of the HPV vaccine among senior secondary girls in Ile-Ife. Methods : This descriptive cross-sectional study recruited 400 students randomly selected from various secondary schools in Ife central-local government. The data was collected with the use of a pre-tested interviewer-administered questionnaire on knowledge, attitude, and acceptability of cervical cancer, HPV and HPV vaccine. Data were analyzed using descriptive and inferential statistics. Results: Most respondents (93.2%) had poor knowledge of cervical cancer, HPV and HPV vaccine. Attitude towards cervical cancer and HPV vaccine was good and the majority (74.5% ) had high acceptability for the HPV vaccine. Only 2.8% of the respondents have been vaccinated. Predictors of acceptability of HPV vaccine were younger age group ((AOR) 4.05 ,CI= 2.30-5.45), good knowledge ((AOR =2.50,CI=2.31-6.83) , mother’ higher level of education (AOR= 1.55, CI=2.62- 4.58 ), perceived fatality of cervical cancer ( AOR=4.13,CI=1.49 – 4.19) and perceived efficacy of the HPV vaccine( AOR=1.57, CI= 0.49 – 3.18). Conclusions: The knowledge of secondary school girls in the study area on cervical cancer, HPV and HPV vaccine is poor though the HPV vaccine acceptability is high. The high acceptability of the vaccine in this study is a reflection of the willingness of this vulnerable group to learn more about the subject matter. There is the need to create school health programs that will focus on health educating the students on this preventable cancer and the available vaccine. Including HPV vaccine into National immunization program in Nigeria may also improve awareness of cervical cancer and the vaccine uptake.
{"title":"PREDITORS AND ACCEPTABILITY OF HUMAN PAPILLOMA VIRUS VACCINE UPTAKE AMONG SENIOR SECONDARY SCHOOL STUDENTS IN ILE-IFE","authors":"F. Fehintola, A. Fehintola, O. Ogundele, C. Adegbenro, S. olowookere, O. Afolabi","doi":"10.24125/SANAMED.V14I2.316","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.316","url":null,"abstract":"Introduction: Cervical cancer is the second most common cancer in women worldwide and in Nigeria. Human papilloma virus (HPV), has been implicated as the causative agent of cervical cancer. The fact that HPV vaccination can prevent the occurrence of this deadly cancer is well established. Though the vaccine has been licensed in Nigeria since 2008 with widespread availability, it is yet to be included in National immunization program in Nigeria. This study aimed to assess the predictors and acceptability of the HPV vaccine among senior secondary girls in Ile-Ife. Methods : This descriptive cross-sectional study recruited 400 students randomly selected from various secondary schools in Ife central-local government. The data was collected with the use of a pre-tested interviewer-administered questionnaire on knowledge, attitude, and acceptability of cervical cancer, HPV and HPV vaccine. Data were analyzed using descriptive and inferential statistics. Results: Most respondents (93.2%) had poor knowledge of cervical cancer, HPV and HPV vaccine. Attitude towards cervical cancer and HPV vaccine was good and the majority (74.5% ) had high acceptability for the HPV vaccine. Only 2.8% of the respondents have been vaccinated. Predictors of acceptability of HPV vaccine were younger age group ((AOR) 4.05 ,CI= 2.30-5.45), good knowledge ((AOR =2.50,CI=2.31-6.83) , mother’ higher level of education (AOR= 1.55, CI=2.62- 4.58 ), perceived fatality of cervical cancer ( AOR=4.13,CI=1.49 – 4.19) and perceived efficacy of the HPV vaccine( AOR=1.57, CI= 0.49 – 3.18). Conclusions: The knowledge of secondary school girls in the study area on cervical cancer, HPV and HPV vaccine is poor though the HPV vaccine acceptability is high. The high acceptability of the vaccine in this study is a reflection of the willingness of this vulnerable group to learn more about the subject matter. There is the need to create school health programs that will focus on health educating the students on this preventable cancer and the available vaccine. Including HPV vaccine into National immunization program in Nigeria may also improve awareness of cervical cancer and the vaccine uptake.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43668434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.339
Dragan Vasin, K. Doklestić, M. Stojadinović, A. Filipović, J. Kovač, D. Mašulović
Introduction: Accessory liver lobes (ALL) are defined as supranumerary liver lobes, composed of normal liver parenchyma in continuity with the liver, in contrast to ectopic liver lobes (ELL) that have no anatomical continuity with the normal liver. Case report :In this article we report on a rare radiological diagnosis of an synchronous accessory and ectopic liver lobe using ultrasonography (US) and computed tomography (CT). A 59-year-old female with no symptoms was admitted to our hospital due to preventive exam. Abdominal ultrasonography revealed a high echoic 6cm x 5cm soft tissue area in right anterior subhepatic space with distinct margins, a uniform echo and blood flow and was suspected to be abdominal tumor. An enhanced abdominal computed tomography (CT) showed the irregular 65mm x 48mm x 32mm mass in the right hypochondrium below IV and V liver segment with clear margins, a uniform density, texture and contrast enhancement as normal liver tissue. In same patient CT also showed small 16mm x 12mm mass in posterior mediastinum in right retrocrural space so diagnosis of accessory and ectopic liver lobe was confirmed. An accessory liver lobe is adjacent and attached to the liver by its own mesentery, while an ectopic liver lobe is one that is completely detached from the normal liver parenchyma. Conclusion :Ultrasound can show mass in the abdomen, which is most commonly in the subhepatic area, but very rarely can initially diagnose ALL or ELL due to different echogenicity of the liver parenchyma in different acoustic windows. In the case of an atypical CT presentation, an MR examination of the abdomen is indicated but it is very rarely. Fast and accurate radiological diagnosis of ALL and ELL is important in the prevention of unnecessary invasive diagnostic procedures such as laparotomy and thoracotomy which are needed only in cases of complications.
{"title":"ACCESORY AND ECTOPIC LIVER LOBE AT SAME PATIENT:CASE REPORT","authors":"Dragan Vasin, K. Doklestić, M. Stojadinović, A. Filipović, J. Kovač, D. Mašulović","doi":"10.24125/SANAMED.V14I2.339","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.339","url":null,"abstract":"Introduction: Accessory liver lobes (ALL) are defined as supranumerary liver lobes, composed of normal liver parenchyma in continuity with the liver, in contrast to ectopic liver lobes (ELL) that have no anatomical continuity with the normal liver. Case report :In this article we report on a rare radiological diagnosis of an synchronous accessory and ectopic liver lobe using ultrasonography (US) and computed tomography (CT). A 59-year-old female with no symptoms was admitted to our hospital due to preventive exam. Abdominal ultrasonography revealed a high echoic 6cm x 5cm soft tissue area in right anterior subhepatic space with distinct margins, a uniform echo and blood flow and was suspected to be abdominal tumor. An enhanced abdominal computed tomography (CT) showed the irregular 65mm x 48mm x 32mm mass in the right hypochondrium below IV and V liver segment with clear margins, a uniform density, texture and contrast enhancement as normal liver tissue. In same patient CT also showed small 16mm x 12mm mass in posterior mediastinum in right retrocrural space so diagnosis of accessory and ectopic liver lobe was confirmed. An accessory liver lobe is adjacent and attached to the liver by its own mesentery, while an ectopic liver lobe is one that is completely detached from the normal liver parenchyma. Conclusion :Ultrasound can show mass in the abdomen, which is most commonly in the subhepatic area, but very rarely can initially diagnose ALL or ELL due to different echogenicity of the liver parenchyma in different acoustic windows. In the case of an atypical CT presentation, an MR examination of the abdomen is indicated but it is very rarely. Fast and accurate radiological diagnosis of ALL and ELL is important in the prevention of unnecessary invasive diagnostic procedures such as laparotomy and thoracotomy which are needed only in cases of complications.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41498863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-04DOI: 10.24125/SANAMED.V14I2.331
B. Abaylı, G. Gençdal
Background and Aim: Acute upper gastrointestinal bleeding (AUGIB) is one of the most common medical emergencies. Early detection of at-risk patients is beneficial with respect to treatment and prognosis. We investigated whether severity of ulcers were associated with red blood cell distribution width (RDW), plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW) . Materials and Methods: All patients presenting to the emergency department with AUGIB between January 2014 and June 2014 were included in the study. Endoscopy reports, complete blood counts, patient demographic characteristics, and endoscopy results were obtained retrospectively from hospital records. Patients with grade I or grade II ulcers (based on the Forrest classification) were compared in regard to these parameters. Results: In total, 373 male and 211 female patients with a mean age ± SD of 66.36 ± 17.36 were included in this study. Ulcers were detected in 396 of 584 patients (67.8%). There were no differences with respect to RDW or platelet indices between groups. Conclusions: Patients presenting with AUGIB should receive rapid diagnosis and treatment. In this study of patients with AUGIB grouped by bleeding aetiology, probable early prognostic parameters were not associated with bleeding severity among patients diagnosed with gastric or duodenal ulcers.
{"title":"RED CELL DISTRIBUTION WIDTH AND PLATELET INDICES AS PREDICTORS IN DETERMINING THE PROGNOSIS OF UPPER GASTROINTESTINAL SYSTEM BLEEDING","authors":"B. Abaylı, G. Gençdal","doi":"10.24125/SANAMED.V14I2.331","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.331","url":null,"abstract":"Background and Aim: Acute upper gastrointestinal bleeding (AUGIB) is one of the most common medical emergencies. Early detection of at-risk patients is beneficial with respect to treatment and prognosis. We investigated whether severity of ulcers were associated with red blood cell distribution width (RDW), plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW) . Materials and Methods: All patients presenting to the emergency department with AUGIB between January 2014 and June 2014 were included in the study. Endoscopy reports, complete blood counts, patient demographic characteristics, and endoscopy results were obtained retrospectively from hospital records. Patients with grade I or grade II ulcers (based on the Forrest classification) were compared in regard to these parameters. Results: In total, 373 male and 211 female patients with a mean age ± SD of 66.36 ± 17.36 were included in this study. Ulcers were detected in 396 of 584 patients (67.8%). There were no differences with respect to RDW or platelet indices between groups. Conclusions: Patients presenting with AUGIB should receive rapid diagnosis and treatment. In this study of patients with AUGIB grouped by bleeding aetiology, probable early prognostic parameters were not associated with bleeding severity among patients diagnosed with gastric or duodenal ulcers.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42278221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-18DOI: 10.24125/SANAMED.V14I2.327
G. Smieško
Urinary infections are, by frequency, in the second place, immediately behind respiratory infections. The prevalence of urinary tract infections is generally increasing. UTI (urinary tract infections) is more common in women and very young people. The rates of occurrence generally reflect predisposing factors such as congenital anomalies in childhood, the onset of sexual activity, especially in women, and, of course, postmenopausal changes in older women. It is assumed that 50-60% of women can expect an episode of urinary infection during their lifetime. In postmenopausal women, there is a deficit in estrogen. It is one of the important factors that indirectly protects the vaginal mucous membranes as well as the uroepitel from infection. Bacteria from the digestive tract colonize the skin of the perineum, then the vulva, the vagina and the outer opening of the urethra. Normal vaginal flora (lactobacilli) protects the vagina from colonization by fecal bacteria because it lowers pH and creates unfavorable conditions for survival of bacteria.
{"title":"INFECTION OF URINARY TRACT IN MENOPAUSAL WOMEN","authors":"G. Smieško","doi":"10.24125/SANAMED.V14I2.327","DOIUrl":"https://doi.org/10.24125/SANAMED.V14I2.327","url":null,"abstract":"Urinary infections are, by frequency, in the second place, immediately behind respiratory infections. The prevalence of urinary tract infections is generally increasing. UTI (urinary tract infections) is more common in women and very young people. The rates of occurrence generally reflect predisposing factors such as congenital anomalies in childhood, the onset of sexual activity, especially in women, and, of course, postmenopausal changes in older women. It is assumed that 50-60% of women can expect an episode of urinary infection during their lifetime. In postmenopausal women, there is a deficit in estrogen. It is one of the important factors that indirectly protects the vaginal mucous membranes as well as the uroepitel from infection. Bacteria from the digestive tract colonize the skin of the perineum, then the vulva, the vagina and the outer opening of the urethra. Normal vaginal flora (lactobacilli) protects the vagina from colonization by fecal bacteria because it lowers pH and creates unfavorable conditions for survival of bacteria.","PeriodicalId":53269,"journal":{"name":"Sanamed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43845298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-18DOI: 10.24125/SANAMED.V14I3.329
G. Smieško
Enterococci are classified as Streptococcus D group. Genetic studies in the 1980s have led to the conclusion that they have enough distinction to be classified into a particular genus. Enterococci cause: urinary infections, especially in patients with catheter, in immunocompromised individuals, the infections of the biliary tract, soft tissue abscess, and wound infection. It is a relatively common cause of endocarditis, especially in people with damaged or artificial heart valve. Enterococci are the most common cause of urinary tract infections (IUT): about 10% of all and about 16% of intra-hospital IUT. In second place in frequency are intra-abdominal and pancreatic wounds, but these infections often cause multiple causes, so the assessment of the importance of enterococci in them is debatable. In third place is the bacteremia most commonly occurring in hospital conditions in immunocompromised patients who are lying long in hospitals and receiving antibiotics.
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