Advances in Difference Equations最新文献

In this paper we consider a standard class of the neural networks and propose an investigation of the global asymptotic stability of these neural systems. The main aim of this investigation is to define a novel Lyapunov functional having quadratic-integral form and use it to reach a stability criterion for the under study neural networks. Since some fundamental characteristics, such as nonlinearity, including time-delays and neutrality, help us design a more realistic and applicable model of neural systems, we will use all of these factors in our neural dynamical systems. At the end, some numerical simulations are presented to illustrate the obtained stability criterion and show the essential role of the time-delays in appearance of the oscillations and stability in the neural networks.

The well-known novel virus (COVID-19) is a new strain of coronavirus family, declared by the World Health Organization (WHO) as a dangerous epidemic. More than 3.5 million positive cases and 250 thousand deaths (up to May 5, 2020) caused by COVID-19 and has affected more than 280 countries over the world. Therefore studying the prediction of this virus spreading in further attracts a major public attention. In the Arab Emirates (UAE), up to the same date, there are 14,730 positive cases and 137 deaths according to national authorities. In this work, we study a dynamical model based on the fractional derivatives of nonlinear equations that describe the outbreak of COVID-19 according to the available infection data announced and approved by the national committee in the press. We simulate the available total cases reported based on Riesz wavelets generated by some refinable functions, namely the smoothed pseudosplines of types I and II with high vanishing moments. Based on these data, we also consider the formulation of the pandemic model using the Caputo fractional derivative. Then we numerically solve the nonlinear system that describes the dynamics of COVID-19 with given resources based on the collocation Riesz wavelet system constructed. We present graphical illustrations of the numerical solutions with parameters of the model handled under different situations. We anticipate that these results will contribute to the ongoing research to reduce the spreading of the virus and infection cases.

The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could represent movements between spatial locations, changes of individual activities or behaviors, or others. To include a sufficiently general disease model, we first build up from first principles a discrete-time susceptible-exposed-infectious-recovered-susceptible (SEIRS) model and characterize the eradication or endemicity of the disease with the help of its basic reproduction number $R_0$ . Then, we propose a general full model that includes sequentially the two processes at different time scales and proceed to its analysis through a reduced model. The basic reproduction number ${\bar{R}}_0$ of the reduced system gives a good approximation of $R_0$ of the full model since it serves at analyzing its asymptotic behavior. As an illustration of the proposed general framework, it is shown that there exist conditions under which a locally endemic disease, considering isolated patches in a metapopulation, can be eradicated globally by establishing the appropriate movements between patches.

As is well known the novel coronavirus (COVID-19) is a zoonotic virus and our model is concerned with the effect of the zoonotic source of the coronavirus during the outbreak in China. We present a SEIS complex network epidemic model for the novel coronavirus. Our model is presented in fractional form and with varying population. The steady states and the basic reproductive number are calculated. We also present some numerical examples and the sensitivity analysis of the basic reproductive number for the parameters.

The development of COVID-19 vaccine is highly concerned by all countries in the world. So far, many kinds of COVID-19 vaccines have entered phase III clinical trial. However, it is difficult to deliver COVID-19 vaccines efficiently and safely to the areas affected by the epidemic. This paper focuses on vaccine transportation in a supply chain model composed of one distributor and one retailer (clinic or hospital), in which the distributor procures COVID-19 vaccines from the manufacturer and then resells them to the retailer. Distributor detects the activity level of the vaccines, and retailer is responsible for transportation of the vaccines. Firstly, we establish a difference equations model with time-delay. Secondly, we investigate the impact of time-delay on the stability of vaccine supply chain. In addition, we explore the influence of decision adjustment speed of the distributor (or retailer) on the stability of vaccine supply chain. Finally, we verify the theoretical results by a two-dimensional bifurcation diagram, the largest Lyapunov exponent, entropy, and domain of attraction. The results show that when the decision delay-time or the adjustment speed of decision variables exceeds a certain threshold, it brings a negative impact on the stability of vaccine supply chain system. The stability domain of the system shrinks as customers' sensitivity to cold chain transportation decreases and by contrast expends as customers' sensitivity to vaccine prices decreases. When the vaccine supply chain is in a state of chaos, the effect of external control over the system is superior to that of internal control over the system.

In this study we propose a fractional frequency flexible Fourier form fractionally integrated ADF unit-root test, which combines the fractional integration and nonlinear trend as a form of the Fourier function. We provide the asymptotics of the newly proposed test and investigate its small-sample properties. Moreover, we show the best estimators for both fractional frequency and fractional difference operator for our newly proposed test. Finally, an empirical study demonstrates that not considering the structural break and fractional integration simultaneously in the testing process may lead to misleading results about the stochastic behavior of the Covid-19 pandemic.

In this paper, a stochastic SIRV epidemic model with general nonlinear incidence and vaccination is investigated. The value of our study lies in two aspects. Mathematically, with the help of Lyapunov function method and stochastic analysis theory, we obtain a stochastic threshold of the model that completely determines the extinction and persistence of the epidemic. Epidemiologically, we find that random fluctuations can suppress disease outbreak, which can provide us some useful control strategies to regulate disease dynamics. In other words, neglecting random perturbations overestimates the ability of the disease to spread. The numerical simulations are given to illustrate the main theoretical results.

We consider a SEAIR epidemic model with Atangana-Baleanu fractional-order derivative. We approximate the solution of the model using the numerical scheme developed by Toufic and Atangana. The numerical simulation corresponding to several fractional orders shows that, as the fractional order reduces from 1, the spread of the endemic grows slower. Optimal control analysis and simulation show that the control strategy designed is operative in reducing the number of cases in different compartments. Moreover, simulating the optimal profile revealed that reducing the fractional-order from 1 leads to the need for quick starting of the application of the designed control strategy at the maximum possible level and maintaining it for the majority of the period of the pandemic.

The Ebola outbreak in 2014 caused many infections and deaths. Some literature works have proposed some models to study Ebola virus, such as SIR, SIS, SEIR, etc. It is proved that the fractional order model can describe epidemic dynamics better than the integer order model. In this paper, we propose a fractional order Ebola system and analyze the nonnegative solution, the basic reproduction number $R_0$ , and the stabilities of equilibrium points for the system firstly. In many studies, the numerical solutions of some models cannot fit very well with the real data. Thus, to show the dynamics of the Ebola epidemic, the Gorenflo-Mainardi-Moretti-Paradisi scheme (GMMP) is taken to get the numerical solution of the SEIR fractional order Ebola system and the modified grid approximation method (MGAM) is used to acquire the parameters of the SEIR fractional order Ebola system. We consider that the GMMP method may lead to absurd numerical solutions, so its stability and convergence are given. Then, the new fractional orders, parameters, and the root-mean-square relative error $g\left(U^{\ast }\right)=0.4146$ are obtained. With the new fractional orders and parameters, the numerical solution of the SEIR fractional order Ebola system is closer to the real data than those models in other literature works. Meanwhile, we find that most of the fractional order Ebola systems have the same order. Hence, the fractional order Ebola system with different orders using the Caputo derivatives is also studied. We also adopt the MGAM algorithm to obtain the new orders, parameters, and the root-mean-square relative error which is $g\left(U^{\ast }\right)=0.2744$ . With the new parameters and orders, the fractional order Ebola systems with different orders fit very well with the real data.

In this paper, we have mathematically analyzed a within-host model of SARS-CoV-2 which is used by Li et al. in the paper "The within-host viral kinetics of SARS-CoV-2" published in (Math. Biosci. Eng. 17(4):2853-2861, 2020). Important properties of the model, like nonnegativity of solutions and their boundedness, are established. Also, we have calculated the basic reproduction number which is an important parameter in the infection models. From stability analysis of the model, it is found that stability of the biologically feasible steady states are determined by the basic reproduction number $\left({\chi }_0\right)$ . Numerical simulations are done in order to substantiate analytical results. A biological implication from this study is that a COVID-19 patient with less than one basic reproduction ratio can automatically recover from the infection.