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EVALUASI STABILITAS FISIK KRIM M/A EKSTRAK BIJI ALPUKAT (Persea americana Mill.) DENGAN VARIASI ASAM STEARAT DAN TEA SEBAGAI EMULGATOR 评价鳄梨籽提取物的生理稳定性。红醋酸和茶的混合物
Pub Date : 2021-11-18 DOI: 10.35799/jm.v11i1.36786
K. L. Mansauda, Imam Jayanto, Ryan Irwanto Tunggal
Biji alpukat (Persea americana Mill.) telah diteliti mengandung senyawa-senyawa metabolit sekunder yang memiliki banyak manfaat misalnya antioksidan, antimikroba, dan antifungi. Penelitian ini bertujuan untuk memformulasikan dan mengevaluasi stabilitas fisik krim ekstrak biji alpukat dengan variasi asam stearat dan TEA sebagai agen pengemulsi. Biji alpukat diekstraksi dengan menggunakan pelarut aseton 70% kemudian diformulasikan menjadi krim M/A. Formulasi krim diuji stabilitasnya dengan uji penyimpanan pada suhu  tinggi (40±2ºC), suhu kamar (25º±2C), dan pada suhu rendah (4±2ºC) selama 8 minggu. Krim juga diuji stabilitasnya menggunakan uji sentrifugasi dan cycling test. Hasilnya krim F1 dan F2 berhasil mempertahankan karakteristik fisiknya seperti penampilan, pH, daya sebar dan daya lekat selama penyimpanan dan memenuhi spesifikasi pada uji sentrifugasi dan cycling test.
鳄梨籽(american polya Mill)被研究为含有一种二级代谢物质,具有抗氧化剂、抗菌素和抗真菌等许多好处。本研究旨在制定和评估鳄梨籽提取物的物理稳定性,其含盐酸和茶的变体为乳化剂。鳄梨籽采用丙酮溶剂提取,然后重新提炼成M/A奶油。配方乳霜和存储测试高温稳定性测试(40±2ºC),室温(25º±2C),较低的温度(4±2ºC) 8星期。奶油还通过离心机和循环测试测试测试,测试稳定剂。结果是F1和F2的乳霜在储存过程中保留了它们的物理特征,如外观、pH、散度和粘性,并符合离心机和循环测试的规范。
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引用次数: 1
Pengaruh Pemberian Sari Buah Salak (Salacca zalacca) terhadap Profil lipid dan Berat Badan Tikus Model Hiperlipidemia dan Obesitasda
Pub Date : 2021-11-13 DOI: 10.35799/jm.v11i1.36530
O. Datu, J. S. Lebang, E. Rumondor
Cardiovaskular disease is the number one cause of death in the world, an estimated 17.9 million people die each year. Several risk factors that contribute to the occurrence of heart disease such as hypertension, diabetes mellitus, hyperlipidemia, and obesity. Snake Fruit is a fruit that is available in large quantities both in volume and variety. Snake Fruit is rich in antioxidants that can be used to treat hyperlipidemia and overweight. North Sulawesi is one of the centers of Snake Fruit production, especially in the southeast Minahasa area. This study aimed to test the effectiveness of Snake Fruit juice on the lipid profile of hyperlipidemic and obese rats induced by a high-fat diet in the form of used cooking oil, quail egg yolk and 0.01% PTU solution. The study used 5 groups, namely the negative control group was given aquadest, the positive control group was given simvastatin and the treatment group was given Snake Fruit juice with concentrations of 2%, 4% and 8%. The parameters observed in this study were body weight, lipid profile, and glucose profile. blood. The study showed that the administration of Snake Fruit juice had a significant effect on the lipid profile of rats for all parameters on the lipid profile and had a significant effect on weight loss and blood glucose levels where p < 0.05 and there was no significant difference between each treatment group in both lipid profile parameters. , body weight and blood glucose levels.
心血管疾病是世界上的头号死因,估计每年有1790万人死亡。导致心脏病发生的几个危险因素,如高血压、糖尿病、高脂血症和肥胖。蛇果是一种数量和品种都很丰富的水果。蛇果富含抗氧化剂,可用于治疗高脂血症和超重。北苏拉威西是蛇果生产的中心之一,特别是在东南部的米纳哈萨地区。本研究旨在研究蛇果汁对高脂饮食(用过的食用油、鹌鹑蛋黄和0.01% PTU溶液)诱导的高脂血症和肥胖大鼠的脂质谱的影响。研究共设5组,阴性对照组给予aquadest,阳性对照组给予辛伐他汀,治疗组给予浓度分别为2%、4%和8%的蛇果汁。在这项研究中观察到的参数是体重、血脂和血糖。血。研究表明,给药蛇果汁对大鼠血脂各参数均有显著影响,对减肥和血糖水平均有显著影响(p < 0.05),且各处理组间血脂参数均无显著差异。体重和血糖水平。
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引用次数: 2
Analisis Hubungan Kekerabatan Fenetik serta Potensi Kegunaan Varietas Portulaca oleracea dan Portulaca grandiflora di Desa Grogol, Kelurahan Dukuh, Kota Salatiga 分析了菲伦理学的联系,以及葡萄牙oleracea和葡萄牙葡萄牙花岗岩品种的潜在用途
Pub Date : 2021-10-06 DOI: 10.35799/jm.v11i1.35054
Henokh Christian Prasgi, Dimas Seno Bagus Pratama, Agnesya Giovani Putri Cendana Kapitarauw, Sri Kasmiyati
Portulacaceae merupakan tumbuhan dikotil dari famili Portulacaceae yang dapat hidup di berbagai kondisi tanah sehingga disebut gulma serta memiliki bentuk dan variasi warna bunga yang beragam untuk dijadikan tanaman hias. Portulaca memiliki berbagai kegunaan untuk kesehatan, sehingga diperlukan suatu program pemuliaan tanaman yang didasarkan pada kekekerabatan menggunakan karakter morfologinya. Tujuan penelitian ini untuk mengetahui hubungan kekerabatan atau fenetik serta sifat kegunaan dari beberapa varietas Portulaca oleracea dan Portulaca grandiflora di Desa Grogol, Kelurahan Dukuh, Kota Salatiga dengan metode Analysis of Cluster dan Euclidean Matrix of Index Dissimilarity. Penelitian ini dilaksanakan di Desa Grogol, Kelurahan Dukuh, Kecamatan Sidomukti, Kota Salatiga, Jawa Tengah. Jenis penelitian deskiptif eksploratif. Karakter yang digunakan sebanyak 22 buah yang dianalis denggan program PAST. Hasil penelitian menunjukkan 6 anggota famili Portulacaceae yang dianalisis dengan metode Analysis of Cluster membentuk 2 klaster utama yaitu klaster 1 Portulaca grandiflora (Oranye, Putih, dan Pink) serta klaster 2 Portulaca oleracea (Kuning. Merah, dan Pink) dengan indeks kesamaan terbesar pada P. grandiflora Oranye dengan P. grandiflora Putih serta P. grandiflora Putih dengan P. grandiflora Pink (99%), sedangkan yang terendah antara Portulaca grandiflora Oranye dengan Portulaca oleracea Merah (94,8038%). Pigmen, faktor genetik, dan lingkungan menyebabkan perbedaan karakter. Kedua spesies ini berpeluang besar dalam pengembangan obat-obatan karena senyawa dan sifatnya.
葡萄牙是一种葡萄牙科植物,它可以生活在不同的土壤条件下,因此被称为杂草,并有不同颜色的花的形状和颜色来装饰植物。葡萄牙有各种各样的健康用途,所以它需要一种以形态特征为基础的植物繁殖计划。本研究的目的是确定几种不同种类的葡属oleracea和葡属纲与两种葡萄牙oleracea和葡聚糖甘菊的相关或相关性质。这项研究是在爪哇中部萨拉提提市的格罗戈村Dukuh村进行的。一种探索性deskiptif研究。分析后使用了22个字符。研究结果显示,六名葡萄牙家族成员通过分析星系团分析的方法分析出,他们组成了两组主要的葡萄牙颗粒状(橙色、白色和粉色)和两组oleracea(黄色)。红色和粉色P. orange grandiflora和白色P. grandiflora与粉色P. grandiflora(99%)有最大的相似之处,而葡萄牙橙色granlaca和红色葡属oleracea(94.8038%)之间的最低等。色素、遗传因素和环境导致性格差异。由于化合物及其性质,这两个物种在药物开发方面都有很大的机会。
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引用次数: 0
Profil Penetrasi Sediaan Gel Antioksidan Ekstrak Kayu Manis (Cinnamomum burmanii) dengan Variasi Hydrocolloid sebagai Gelling agent
Pub Date : 2021-09-13 DOI: 10.35799/jm.v11i1.35787
J. P. Siampa, W. Wiyono, Utami Sasmita Lestari, J. S. Lebang, Irma Antasionasti
The exposure of sunlight consisting UV radiation has been reported to be the main cause of skin cancer and contribute about 80% of the incidence of skin damage. In an attempt to overcome this problem, antioxidant agents have been used both orally and topically. Compared to oral administration, topical route has been found to be preferred due to the direct action to the desired site. Amongst topical preparation, gel possesses numerous because it provides a cool and fresh sensation. Here, we developed gel antioxidant containing cinnamon extract as active ingredient. Cinnamon was selected as it has a very strong antioxidant activity. This study aimed to obtain the penetration profile of the antioxidant gel of cinnamon extract prepared from two different hydrocolloid agents. The gels were made using various concentrations of Carbopol 940 and NaCMC. The prepared gels were further characterized for their antioxidant capacities using the DPPH free radical scavenging method and their total phenolic contents using the spectrophotometric method. The formulation possessing the strongest antioxidant capacity was continued for ex vivo penetration study using Franz diffusion cells. The results exhibited that the total phenolic value of the cinnamon extract obtained was 908.38 ± 6.54 mg GAE/g extract. The penetration percentages for the formula with Carbopol and NaCMC bases were 53.310 ± 1.217% and 27.969 ± 1.151%, respectively, and the retention percentages were 28.495 ± 0.031% and 18.356 ± 0.191%, respectively. Based on these findings, we concluded that cinnamon extract could potentially be formulated into antioxidant gel preparations and formulas based on Carbopol showed the best penetration profile.
据报道,暴露在阳光下的紫外线辐射是皮肤癌的主要原因,约占皮肤损伤发生率的80%。为了克服这个问题,抗氧化剂已经被口服和局部使用。与口服给药相比,由于直接作用于所需部位,局部给药途径被认为是首选。在外用制剂中,凝胶具有许多,因为它提供凉爽和新鲜的感觉。本文研制了以肉桂提取物为活性成分的凝胶抗氧化剂。选择肉桂是因为它具有很强的抗氧化活性。本研究旨在获得两种不同水胶体剂制备的肉桂提取物的抗氧化凝胶的渗透特性。用不同浓度的Carbopol 940和NaCMC制备凝胶。用DPPH自由基清除法和分光光度法对制备的凝胶进行了抗氧化能力和总酚含量的表征。采用Franz扩散细胞对抗氧化能力最强的配方进行体外渗透研究。结果表明,肉桂提取物的总酚值为908.38±6.54 mg GAE/g提取物。以卡波波尔和NaCMC为碱基的配方,渗透率分别为53.310±1.217%和27.969±1.151%,滞留率分别为28.495±0.031%和18.356±0.191%。研究结果表明,肉桂提取物具有制备抗氧化凝胶的潜力,以卡波波尔为基础的抗氧化凝胶具有最佳的渗透效果。
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引用次数: 0
Potensi Metode Sonic Bloom untuk Meningkatkan Pertumbuhan Tanaman 声波布鲁姆改善植物生长的潜力
Pub Date : 2021-06-18 DOI: 10.35799/jmuo.10.2.2021.34345
Song Ai Nio, Julia Angel Rumbay, Putri Sri Anggini, Patrycia Saskia Laurita Supit, D. Ludong
Metode sonic bloom merupakan pengembangan ilmu pengetahuan dan teknologi di bidang pertanian yang memanfaatkan gelombang suara dengan frekuensi tinggi tanpa merusak lingkungan. Aplikasi sonic bloom berpotensi untuk meningkatkan pertumbuhan pada tanaman yang ditunjukkan dengan adanya peningkatan pembukaan stomata, perkecambahan, pertumbuhan (tinggi tanaman, tinggi dan diameter batang, panjang dan lebar daun, dan panjang akar) serta produktivitas. Metode sonic bloom yang efektif menggunakan bunyi dengan rata-rata intensitas bunyi 65-75 dB, frekuensi bunyi 3-5 kHz dan lama pemaparan 3 jam per hari serta variasi jenis musik.  Gelombang bunyi ini menginduksi pembukaan stomata yang berdampak pada peningkatan penyerapan CO2, H2O dan unsur-unsur hara oleh tanamanThe sonic bloom method is the development of science and technology in agriculture that utilizes high-frequency sound waves without damaging the environment. Sonic bloom application was potential to increase plant growth as indicated by an increase in stomata opening, germination, growth (plant height, height and diameter of stem, length and width of leaf, and root length) and productivity. An effective sonic bloom method used sound with an average sound intensity of 65-75 dB, a sound frequency of 3-5 kHz and an exposure time of 3 hours per day as well as a variety of types of music. This sound wave induced the opening of stomata which had an impact on increasing the absorption of CO2, H2O and nutrients by plants.
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引用次数: 5
Formulasi dan Karakterisasi Minuman Emulsi Virgin Coconut Oil dengan Penambahan Jahe Merah (Zingiber Officinale VAR. Rubrum) dan Sereh (Cymbopogon Nardus L. Rendle) 用红姜(Zingiber Officinale VAR. Rubrum)和Sereh (Cymbopogon Nardus L. Rendle)调制和描述等饮料
Pub Date : 2021-06-09 DOI: 10.35799/jmuo.10.2.2021.34183
Amanda Archangela Koleangan, G. Djarkasi, L. Mandey
Virgin Coconut Oil (VCO) yang merupakan salah satu produk olahan kelapa yang memiliki banyak manfaat kesehatan sulit dikonsumsi secara langsung karena rasanya yang berminyak (oily). Oleh karena itu, untuk membuatnya enak dikonsumsi, VCO dibuat dalam bentuk minuman emulsi. Pada penelitian ini, minuman emulsi VCO ditambahkan dengan jahe merah dan sereh yang bertujuan untuk menyelidiki pengaruh penambahan jahe merah dan sereh pada karakteristik fisik, kimia, aktivitas antioksidan, dan tingkat kesukaan panelis terhadap minuman emulsi VCO. Konsentrasi jahe merah dan sereh divariasikan: 100% jahe merah, 100% sereh, 50% jahe merah : 50% sereh, 75% jahe merah : 25% sereh, dan 25% jahe merah : 75% sereh. Hasil menunjukkan bahwa konsentrasi jahe merah dan sereh mempengaruhi warna minuman emulsi VCO yang dihasilkan. Penggunaan gum arab (7%) menghasilkan minuman emulsi VCO yang stabil selama waktu pengamatan 7 hari. Total gula (% sukrosa) berkisar pada 26,00%-28,67%. Total fenol dan bilangan peroksida minuman emulsi berkisar dari 20,92 – 28,61 mg GAE/ g sampel dan 0,08-0,79 mg ekuivalen O2/kg. Pada konsentrasi 15 ppm, aktivitas antioksidan minuman emulsi berkisar antara 58,58% - 71,20%. Minuman emulsi dengan penambahan 100% jahe merah paling disukai dalam aroma, warna, dan penampakannya, sedangkan minuman emulsi dengan penambahan 75% jahe merah dan 25% sereh yang paling disukai rasanyaVirgin Coconut Oil (VCO) as one of the coconut products with many health benefits hard to be consumed directly because of its oily taste. Therefore, to make it more tastier to consume, VCO will be made in form of emulsion drink. In this research, VCO emulsion drink will be added with red ginger and lemongrass to investigate the addition effect of these spices on the physical, chemical characteristic, antioxidant activity, and  panelist preference rate of its emulsion drink. The concentrations of red ginger and lemongrass were varied : 100% red ginger, 100% lemongrass, 50% red ginger : 50% lemongrass, 75% red ginger : 25% lemongrass, and 25% red ginger : 75% lemongrass. The result shows that the concentration of red ginger and lemongrass affected the color of the emulsion drink. The addition of arabic gum (7%) produced a stable emulsion drink during the observation time of 7 days. The sucrose percentage of the emulsion drink is 26,00% to 28,67%. The average of total phenol and peroxide numbers in the emulsion drinks was 20,92 to 28,61 mg GAE /g sample and 0,08-0,79 mg equivalent O2 / kg. At a concentration of 15 ppm, the antioxidant activity of emulsion drinks ranged from 58,58% - 71,20%. VCO emulsion drinks with the addition of 100% red ginger were the most preferred in terms of aroma, color, and its appearance, while the addition of 75% red ginger and 25% lemongrass were the most preferred in taste
处女椰子油(VCO)是一种精制的椰子产品,由于其油腻的味道很难直接食用,因此很难直接食用。因此,为了使它更美味,VCO是由乳胶饮料制成的。在这项研究中,VCO乳液与姜红色和sereh混合,旨在研究红色生姜和sereh对VCO乳清饮料的生理、化学、抗氧化剂活性和小组对乳清饮料的喜爱程度的影响。姜红色和sereh的浓度:100%姜红色,100% sereh, 50%姜红色:50% sereh, 75% red姜:25% sereh, 25% red姜:75% sereh。结果表明,红色姜黄和柠檬草的浓度会影响VCO乳品的颜色。在为期7天的观察期间,阿拉伯口香糖(7%)的使用提供了稳定的VCO乳胶饮料。总糖(%蔗糖)的范围为26.00% - 2867%。总苯酚和过氧化物饮料的总数量约为2092 - 2861毫克GAE/ g样本和0.08 - 0.79 mg氧气/kg。在浓度15 ppm时,乳液的抗氧化剂活性在58.58% - 71.20%之间。酒红姜增加100%的乳液中最喜欢的气味、颜色和表面上看,而饮料乳化红姜增加75%和25%的最受欢迎的柠檬草rasanyaVirgin椰子油椰子产品(VCO)美国一号》和许多health benefits to be consumed硬盘直接的,因为它的oily品味。因此,为了使它更有说服力,VCO将被制成乳品饮料。在这项研究中,VCO emulsion饮料将添加红色和柠檬的成分,以研究这些香料在物理、化学特征、抗氧化剂反应和其快速反应饮料的副作用。红姜和柠檬的集中是不同的:100%红姜,100%蓝姜,50%红姜:50%红姜,75%红姜:25%深姜,25%红姜:75%深姜。最近的广告显示,红姜和嫩草的浓度影响了乳液的颜色。阿拉伯口香糖的补充(7%)是在观察7天的时候生产一种稳定的乳液。牛奶牛奶的中转站是26.00%到2867%。牛奶饮料中总苯酚和过氧化物的数量为2092至2861毫克香槟和0.08 - 0.79毫克的equivalent氧气/ kg。在15个ppm的集中集中,抗氧化剂酒精饮料的活性含量从58.58%到71.20%。VCO乳液中加入100%红色姜基的饮料是最受欢迎的香气、颜色和外观,而75%的红姜黄和25%的柠檬是最受欢迎的口味
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引用次数: 0
Analisis Kestabilan Model Epidemi Sjat Pada Penyebaran Penyakit Aids Di Kecamatan Pujer Kabupaten Bondowoso
Pub Date : 2021-05-25 DOI: 10.35799/jmuo.10.2.2021.34090
T. D. Chandra, Agesta Ameliya Putri
HIV berkembang menjadi Acquired Immune Deficiency Syndrome (AIDS) mengakibatkan kematian dengan melemahnya sistem imun dan mudahnya penyakit masuk ke dalam tubuh seseorang. Model matematika SJAT digunakan untuk menganalisis penyebaran AIDS dengan terdiri empat kelas yaitu kelas individu rentan, kelas individu terinfeksi HIV dengan gejala, kelas individu AIDS dan kelas individu mendapatkan pengobatan ARV. Tujuan penelitian ini yaitu melihat dinamika penyebaran penyakit AIDS, melakukan simulasi model terhadap penyebaran penyait AIDS di Kecamatan Pujer Kabupaten Bondowoso. Tahap menganalisis model yaitu mencari titik kesetimbangan, menganalisa titik setimbang, mencari bilangan reproduksi dasar, dan melakukan simulasi model menggunakan maple17. Berdasarkan hasil analisa diperoleh 0,02222489365  Sehingga mempunyai titik setimbang bebas penyakit. Artinya, pada waktu lama proporsi individu akan menuju titik kesetimbangan dengan rata-rata penyakit AIDS dalam populasi sudah tidak menyebarHIV develops into Acquired Immune Deficiency Syndrome (AIDS) resulting in death by weakening the immune system and the ease with which diseases enter a person's body. The SJAT mathematical model is used to analyze the spread of AIDS and consists of four classes, namely a class of susceptible individuals, a class of HIV-infected individuals with symptoms, a class of AIDS individuals and a class of individuals receiving ARV treatment. The purpose of this study is to analyze the stability of the SJAT Epidemic Model Stability on the HIV/AIDS AIDS in Pujer District Bondowoso Regency. The stage of analyzing the model is to find the equilibrium point, analyze the equilibrium point, find the basic reproduction number, and simulate the model using maple17. Based on the analysis results obtained . So that it has a disease-free equilibrium point. This means that in a long time the proportion of individuals will come to a point of equilibrium with the average AIDS disease in the population has not spread
艾滋病毒发展成免疫系统衰弱和疾病容易进入人体,导致死亡。SJAT的数学模型被用来分析艾滋病的传播,它由四年级的易受感染的个人班、症状感染的个人阶层、个人艾滋病班和个人阶层获得抗逆转录病毒治疗。这项研究的目的是观察艾滋病的传播动力学,模拟邦多沃索区艾滋病传播的模型。分析模型的阶段包括找到平衡点,分析精定点,找到基本的生殖数,用maple17进行模拟模型。根据分析获得了0.02222489365,使其没有疾病的临床点。这意味着,长期以来,一个人将达到平均水平的平衡,艾滋病毒发展到获得艾滋病毒缺乏性免疫缺陷综合症(艾滋病)。SJAT mathematical模型是用来分析艾滋病的传播和四年级的表现,namely是一个令人兴奋的个体,一个带有交响曲的高度感染的个人,一个带有艾滋病的个人接受抗逆转录病毒的个人。这项研究的目的是分析艾滋病毒/艾滋病在我国摄政区的稳定模式。分析模型的舞台分析是找到平衡点,分析平衡点,找到基本复制数字,用maple17模拟模型。基于对象分析分析。所以它有一种特殊的中和点。这意味着在很长一段时间内,个人的比例将达到平均艾滋病疾病的平衡
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引用次数: 1
Nilai Indeks Aterogenik Plasma (IAP) Dan Indeks Castelli (IC) Mencit Model yang Diinduksi Minyak Trans
Pub Date : 2021-05-25 DOI: 10.35799/jmuo.10.2.2021.34094
Atin Supiyani, Dalia Sukmawati, Nastiti Kusumorini, Koekoeh Santoso, A. Satyaningtijas
dikembangkan melalui pendekatan hewan model untuk mempelajari tentang PJK. Minyak goreng yang digunakan secara berulang dapat meningkatkan kadar asam lemak bebas yang berdampak negatif bagi kesehatan terutama jantung dan pembuluh. Tujuan dari penelitian ini mengukur indeks aterogenik plasma (IAP) dan indeks Castelli (IC) dari mencit model yang diinduksi minyak trans (MT). Sebanyak 16 ekor mencit galur DDY dibagi menjadi 4 kelompok yaitu mencit yang diinduksi 20% minyak trans (MT20), 40% minyak trans (MT40) dan 60% minyak trans (MT60) dan kontrol (K). Persentase minyak trans diberikan berdasarkan dari total energi konsumsi pakan harian. Minyak trans diberikan per oral sehari sekali selama 70 hari. Darah diambil pada hari ke-70 dari vena lateral ekor tikus untuk mengukur profil lipid plasma yaitu kolesterol total, trigliserida (TG), High Density Lippoprotein (HDL) dan Low Density Lipoprotein (LDL) plasma  menggunakan alat uji cepat Lipid Pro®. Nilai Indeks Aterogenik Plasma (IAP) yaitu log (TG/HDL) dan Indeks Castelli (IC) yaitu LDL/HDL. Hasil pengkuran profil lipid plasma menunjukkan kolesterol total, trigliserida, HDL dan LDL plasma pada kelompok MT meningkat secara nyata dibandingkan kontrol (sig<0,05). Nilai IA pada mencit yang diberi minyak trans berbeda nyata dari kontrol (sig<0,05) dan memiliki risiko tinggi. Nilai IC pada mencit yang diberi minyak trans berbeda nyata dari kontrol (sig<0,05) dan memiliki risiko sedang-tinggi. Minyak trans meningkatkan nilai indeks aterosklerosis dan indeks resiko koroner mencit.Coronary Heart Disease (CHD) is a "silent killer" disease. Various studies were developed through an animal model approach to studying CHD. Cooking oil that is used repeatedly can increase levels of free fatty acids which have a negative impact on health, especially the heart and vessels. The aim of this study was to measure the plasma atherogenic index (IAP) and Castelli index (IC) of trans oil-induced model mice (MT). A total of 16 DDY mice were divided into 4 groups, namely mice induced with 20% trans oil (MT20), 40% trans oil (MT40) and 60% trans oil (MT60) and control (K). The percentage of trans oil is given based on the total energy consumption of the daily feed. Trans oil is given orally once a day for 70 days. Blood was taken on the 70th day from the lateral vein of the rat tail to measure the plasma lipid profile, namely total cholesterol, triglycerides (TG), High Density Lippoprotein (HDL) and plasma Low Density Lipoprotein (LDL) using the Lipid Pro® rapid test kit. The Plasma Atherogenic Index (IAP) values are log (TG / HDL) and the Castelli Index (IC) is LDL / HDL. The results of measuring the plasma lipid profile showed that plasma total cholesterol, triglycerides, HDL and LDL in the MT group increased significantly compared to the control (sig<0,05). The IA value in mice treated with trans oil was significantly different from the control (sig<0.05) and had a high risk. The IC value in mice treated with trans oil was sig
它是通过动物模型来研究PJK的。反复使用的食用油会增加自由脂肪酸的含量,对心脏和血管的健康产生负面影响。这项研究的目的是测量输液油诱导模型的血浆-电平指数(IAP)和IC - Castelli指数(IC)。16只ngt DDY被分成4组,其中包括chot含有20%的trans oil (MT20), 40%的trans oil (MT40)和60%的trans oil (MT60)和控制(K)。变性油是每天一次,持续70天。横向70日取自静脉血液测量资料的老鼠尾巴脂肪血浆总胆固醇、甘油三酯(海岬)的高密度Lippoprotein (HDL)和低密度脂蛋白(LDL)使用快速测试工具血浆脂Pro®。血浆-优生指数(IAP)是log (TG/HDL)和Castelli指数(IC)是LDL/HDL。血浆脂介质分解表明,MT组的总胆固醇、甘油三酯、HDL和LDL血浆比控制系统明显增加(sig< 0.05)。他对特格特的得分与控制(sig< 0.05)截然不同,风险很高。pt上的IC值与控制(sig< 0.05)截然不同,具有高风险。变性油会增加动脉粥样硬化指数和冠状动脉风险指数。冠状动脉疾病是一种无声的杀手。各种各样的研究是通过动物模型进行的对发展中的CHD。可燃的油可以增加无脂肪acids的水平,其对健康有负面影响,特别是心脏和车辆。这项研究的目标是测量血浆组织热力学指数和Castelli指数(MT)。16代媒体总共被记录为4个groups, namely mice以20%的trans oil (MT20)、40%的trans oil (MT40)和60%的trans oil (MT60)和控制(K)为基础。Trans oil通常每天提供70天。血是某种程度上的70日从横向静脉》老鼠尾巴到所拘束的血浆脂质低调,namely共有过高,甘油三酯(海岬)形式的高密度等离子Lippoprotein (HDL)和低密度脂蛋白(LDL)用的脂肪Pro®快速测试套件。血浆Atherogenic指数是价值日志,Castelli指数是LDL / HDL。装饰等离子体资料的结果表明,在MT group中,血浆的总胆固醇、三甘油二醇、HDL和LDL对控制的强度越来越高(sig< 0.05)。他对反石油的投资与控制有很大的不同,而且有很高的风险。与反石油公司的损失严重不同,具有中等风险。Trans oil增加了动脉粥样硬化和冠状动脉风险指数。
{"title":"Nilai Indeks Aterogenik Plasma (IAP) Dan Indeks Castelli (IC) Mencit Model yang Diinduksi Minyak Trans","authors":"Atin Supiyani, Dalia Sukmawati, Nastiti Kusumorini, Koekoeh Santoso, A. Satyaningtijas","doi":"10.35799/jmuo.10.2.2021.34094","DOIUrl":"https://doi.org/10.35799/jmuo.10.2.2021.34094","url":null,"abstract":"dikembangkan melalui pendekatan hewan model untuk mempelajari tentang PJK. Minyak goreng yang digunakan secara berulang dapat meningkatkan kadar asam lemak bebas yang berdampak negatif bagi kesehatan terutama jantung dan pembuluh. Tujuan dari penelitian ini mengukur indeks aterogenik plasma (IAP) dan indeks Castelli (IC) dari mencit model yang diinduksi minyak trans (MT). Sebanyak 16 ekor mencit galur DDY dibagi menjadi 4 kelompok yaitu mencit yang diinduksi 20% minyak trans (MT20), 40% minyak trans (MT40) dan 60% minyak trans (MT60) dan kontrol (K). Persentase minyak trans diberikan berdasarkan dari total energi konsumsi pakan harian. Minyak trans diberikan per oral sehari sekali selama 70 hari. Darah diambil pada hari ke-70 dari vena lateral ekor tikus untuk mengukur profil lipid plasma yaitu kolesterol total, trigliserida (TG), High Density Lippoprotein (HDL) dan Low Density Lipoprotein (LDL) plasma  menggunakan alat uji cepat Lipid Pro®. Nilai Indeks Aterogenik Plasma (IAP) yaitu log (TG/HDL) dan Indeks Castelli (IC) yaitu LDL/HDL. Hasil pengkuran profil lipid plasma menunjukkan kolesterol total, trigliserida, HDL dan LDL plasma pada kelompok MT meningkat secara nyata dibandingkan kontrol (sig<0,05). Nilai IA pada mencit yang diberi minyak trans berbeda nyata dari kontrol (sig<0,05) dan memiliki risiko tinggi. Nilai IC pada mencit yang diberi minyak trans berbeda nyata dari kontrol (sig<0,05) dan memiliki risiko sedang-tinggi. Minyak trans meningkatkan nilai indeks aterosklerosis dan indeks resiko koroner mencit.Coronary Heart Disease (CHD) is a \"silent killer\" disease. Various studies were developed through an animal model approach to studying CHD. Cooking oil that is used repeatedly can increase levels of free fatty acids which have a negative impact on health, especially the heart and vessels. The aim of this study was to measure the plasma atherogenic index (IAP) and Castelli index (IC) of trans oil-induced model mice (MT). A total of 16 DDY mice were divided into 4 groups, namely mice induced with 20% trans oil (MT20), 40% trans oil (MT40) and 60% trans oil (MT60) and control (K). The percentage of trans oil is given based on the total energy consumption of the daily feed. Trans oil is given orally once a day for 70 days. Blood was taken on the 70th day from the lateral vein of the rat tail to measure the plasma lipid profile, namely total cholesterol, triglycerides (TG), High Density Lippoprotein (HDL) and plasma Low Density Lipoprotein (LDL) using the Lipid Pro® rapid test kit. The Plasma Atherogenic Index (IAP) values are log (TG / HDL) and the Castelli Index (IC) is LDL / HDL. The results of measuring the plasma lipid profile showed that plasma total cholesterol, triglycerides, HDL and LDL in the MT group increased significantly compared to the control (sig<0,05). The IA value in mice treated with trans oil was significantly different from the control (sig<0.05) and had a high risk. The IC value in mice treated with trans oil was sig","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72641482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pemodelan Perambatan Gelombang Tsunami di Laut Banda Berdasarkan Skenario Gempa 8.0 dan 9.0 Mw
Pub Date : 2021-05-11 DOI: 10.35799/jmuo.10.2.2021.34006
Cynthia Wuwungan, Guntur Pasau, S. H. Tongkukut
Penelitian ini dilakukan untuk menentukan waktu tiba perambatan gelombang dan tinggi gelombang tsunami di Kota Ambon dan sekitarnya dengan melakukan simulasi tsunami menggunakan software ComMIT. Simulasi dijalankan menggunakan skenario yang mengasumsikan kekuatan gempa 8.0 Mw dan 9.0 Mw. Titik koordinat gempa 4.31˚ LU dan 128.61˚ BT. 10 detektor dalam bentuk virtual (tide gauge) dibuat untuk mendapatkan nilai waktu tiba dan tinggi gelombang tsunami. Hasilnya menunjukkan bahwa tsunami tercepat dengan ketinggian 2.17 m tiba pada detik ke-566 dengan mengasumsikan gempa 8.0 Mw dan gempa 9.0 Mw membuat gelombang tsunami dengan tinggi 62.4 m dan tiba pada detik ke-599 di Kota AmbonThe purpose of this research is to determine the arrival time and the height of the tsunami waves in Ambon and its surroundings by conducting a tsunami simulation using ComMIT. The simulation is run using scenario by assuming the earthquake with magnitude 8.0 Mw and 9.0 Mw. The Earthquake epicenter scenario  44.31˚ N and 128.61˚ E. 10 detectors in virtual form (tide gauge) were placed to determine the arrival time and height of the tsunami waves. The results showed that the fastest tsunami with a height of 2.17 m arrived in 566 seconds after the 8.0 Mw earthquake, and the 9.0 Mw earthquake generate a 62.4 m tsunami with 599 second arrival time in Ambon
{"title":"Pemodelan Perambatan Gelombang Tsunami di Laut Banda Berdasarkan Skenario Gempa 8.0 dan 9.0 Mw","authors":"Cynthia Wuwungan, Guntur Pasau, S. H. Tongkukut","doi":"10.35799/jmuo.10.2.2021.34006","DOIUrl":"https://doi.org/10.35799/jmuo.10.2.2021.34006","url":null,"abstract":"Penelitian ini dilakukan untuk menentukan waktu tiba perambatan gelombang dan tinggi gelombang tsunami di Kota Ambon dan sekitarnya dengan melakukan simulasi tsunami menggunakan software ComMIT. Simulasi dijalankan menggunakan skenario yang mengasumsikan kekuatan gempa 8.0 Mw dan 9.0 Mw. Titik koordinat gempa 4.31˚ LU dan 128.61˚ BT. 10 detektor dalam bentuk virtual (tide gauge) dibuat untuk mendapatkan nilai waktu tiba dan tinggi gelombang tsunami. Hasilnya menunjukkan bahwa tsunami tercepat dengan ketinggian 2.17 m tiba pada detik ke-566 dengan mengasumsikan gempa 8.0 Mw dan gempa 9.0 Mw membuat gelombang tsunami dengan tinggi 62.4 m dan tiba pada detik ke-599 di Kota AmbonThe purpose of this research is to determine the arrival time and the height of the tsunami waves in Ambon and its surroundings by conducting a tsunami simulation using ComMIT. The simulation is run using scenario by assuming the earthquake with magnitude 8.0 Mw and 9.0 Mw. The Earthquake epicenter scenario  44.31˚ N and 128.61˚ E. 10 detectors in virtual form (tide gauge) were placed to determine the arrival time and height of the tsunami waves. The results showed that the fastest tsunami with a height of 2.17 m arrived in 566 seconds after the 8.0 Mw earthquake, and the 9.0 Mw earthquake generate a 62.4 m tsunami with 599 second arrival time in Ambon","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84371215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kajian Potensi Energi Angin di Gunung Tumpa Kelurahan Tongkaina Kecamatan Bunaken Kota Manado
Pub Date : 2021-05-10 DOI: 10.35799/jmuo.10.2.2021.33989
Jein Tulong, H. Kolibu, Guntur Pasau, V. Suoth
Telah dilakukan penelitian untuk mengetahui potensi energi angin di gunung Tumpa Kelurahan Tongkaina Kecamatan Bunaken Kota Manado. Lokasi penelitan berada pada koordinat -  LU dan -  BT. Metode penelitian meliputi : pengumpulan data kecepatan angin, perhitungan massa udara, dan potensi energi angin. Hasil penelitian menunjukkan bahwa potensi energi angin selama 2 minggu  di Gunung Tumpa yaitu mulai yang paling rendah 0,0040 watt-day/tahun dan paling tinggi 0,3187 watt-day/tahun. Dengan memperhatikan aspek-aspek di atas, serta menghitungkan kontinuitasnya maka gunung Tumpa memiliki potensi energi angin yang tidak bisa dimanfaatkan sebagai energi listrikResearch has been conducted to determine the potential of wind energy in the mountain Tumpa, Tongkaina Village, Bunaken District, Manado City. The research location is at coordinates 1°30 - 1° 40 LU and 124°40 - 125°50 BT. Research methods include: collecting wind speed data, calculating air mass, and wind energy potential. The results showed that the potential for wind energy for 2 weeks at Mount Tumpa is starting from the lowest 0.0040 watt-day / year and the highest is 0.3187 (watt-day) ahunyear. By paying attention to the above aspects, and calculating its continuity, Mount Tumpa has the potential of wind energy that cannot be utilized as electrical energy
一直在进行研究,以确定在马纳多市bunkaina附近潘凯纳山脉的风力能源潜力。研究方法包括收集风速数据、气量计算和风能电能潜力。研究结果表明,在Tumpa山两周内的风能潜力将以最低0.0040瓦特日/年开始,最高为0.3187天/年。通过对上述方面的考虑,以及对其进行计算,图帕火山具有不可利用的风力能源潜力,目前正在决定图帕山、童工村、马纳多地区、班肯区、马纳多市的潜在风能。《研究位置是at coordinates陆1°30 - 40°和BT 124°40 - 125°50。研究方法include: muensterberger风速度数据,计算潜在的风团,水和能源。结果表明,塔帕山的潜在能源持续了2周,从低海拔0.0040瓦特/年开始,最高气温为0.3187年。通过对上述资产的关注和持续的callapt, Tumpa拥有一种可以像电力一样消耗的风能
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引用次数: 1
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