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Uji Aktivitas Antibakteri Fraksi Daun Sesewanua (Clerodendron squamatum Vahl.) Terhadap Bakteri Streptococcus mutans dan Escherichia coli 测试叶绿体(clerodentum Vahl)的抗菌活性成分。治疗链球菌变异和大肠杆菌
Pub Date : 2021-04-12 DOI: 10.35799/JMUO.10.2.2021.33592
Fantry Nurhayati Kadir, M. Runtuwene, Vanda S. Kamu
Telah dilakukan penelitian mengenai kandungan total fenolik, flavonoid dan tanin terkondensasi dari hasil pemisahan kromatografi kolom dan uji aktivitas antibakteri fraksi daun sesewanua terhadap bakteri Streptococcus mutans dan escherecia coli. Pemisahan kromatografi kolom dimulai dengan proses ekstraksi maserasi menggunakan pelarut metanol. Hasil penelitian menunjukkan bahwa kandungan total fenolik tertinggi pada fraksi metanol yaitu 135,497 mg/g, kandungan total flavonoid tertinggi pada fraksi etil asetat yaitu 102,647 mg/g dan kandungan total tanin terkondensasi tertinggi pada fraksi metanol yaitu 53,543 mg/g.  Uji aktivitas antibakteri menggunakan konsentrasi fraksi 40%, 60% dan 80% dilakukan sebanyak tiga kali pengulangan. Larutan DMSO 10% digunakan sebagai kontrol negatif dan kloramfenikol sebagai kontrol positif. Hasil menunjukkan bahwa fraksi n-heksana tidak memiliki zona hambat sedangkan fraksi etil asetat dan fraksi metanol daun sesewanua dapat menghambat bakteri Streptococcus mutans dan Escherecia coli. Konsentrasi fraksi 80% menunjukkan zona hambat yang paling besarResearch has been conducted on the total content of phenolics, flavonoids and condensed tannins from the results of column chromatography separation. Antibacterial activity test of leaf fractions was also performed against Streptococcus mutans and Escherecia coli. The separation of column chromatography was initialized with the process of maceration using methanol as solvents. The highest total phenolic content obtained in the methanol fraction was 135.497 mg/g, the highest total flavonoid content obtained in the ethyl acetate fraction was 102.647 mg/g and the highest total condensed tannin content in the methanol fraction was 53.543 mg/g. Antibacterial activity test was done triplicates using the 40%, 60% and 80% fraction. DMSO 10% was apllied as the negative control and chloramphenicol as the positive control. The results showed that the n-hexane fraction did not have an inhibition zone while the ethyl acetate fraction and the methanol fraction of the leaves can inhibit Streptococcus mutans and Escherecia coli. Moreover, 80% fraction showed the largest inhibition zone.
研究过一项研究,从列色相色谱仪分离和测试sewancus菌根和escherecia大肠杆菌的二叶抗菌成分而凝聚成醇、黄酮和单宁酸。色谱学分离始于使用甲醇溶剂的人工菌提取过程。研究结果表明,甲醇的总ph值为135,497毫克/g,甲醇的乙醇总ph值为102,647毫克/g,而甲醇的总ph值为53.543毫克/g。抗菌活性测试使用40%、60%和80%的浓度重复三次。10%的DMSO溶液用作负控件,氯仿作为正控件使用。结果表明,n-heksana的n-heksana没有抑制区,而甲基苯丙胺的乙醇和甲醇的叶子成分可以抑制链球菌和Escherecia大肠杆菌。80%的分数集中表明,最广泛研究所涉及的抑制区域是对苯酚、黄体和分层关系关系的结果。叶抑制杆菌试验还受到链球菌和大肠杆菌的抑制。编纂术的分离与人们使用美国溶剂甲烷的修正过程有关。在甲烷溶液中受孕的总苯乙醇为135,497毫克/g,而在乙醇乙醇溶液中受孕的总黄醇为102647毫克/g,在甲烷溶液中完全稀释的甲醇为53,543毫克/g。抗菌活动测试使用40%、60%和80%的帧进行了重复试验。10%的DMSO被认为是负控制,像积极控制一样氯化。结果表明,n-hexane的诱惑在乙基乙醇的腐蚀和甲醇的诱发过程中没有受到抑制。此外,80%的帧显示了区域抑制剂。
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引用次数: 0
Identifikasi Struktur Bawah Permukaan Tuff ring Dengan Menggunakan Metode Geolistrik Konfigurasi Dipol-Dipol 使用校准二极管配置找出土夫环的地下结构
Pub Date : 2021-01-26 DOI: 10.35799/JMUO.10.1.2021.32439
Gregorio Arikalang, Ferdy Ferdy, Guntur Pasau, G. Tamuntuan
Tuff ring Geoelectric Resistivity Dipole-dipole The research has been done to identify the subsurface structure of the tuff ring in plantation area Mahawu using geoelectric method of dipole-dipole configuration.It has been divided into two lines measuring with the length of 480 m for each lines, one space 10 m between the electrodes and the line 2 has 240 m length with spaces 5 m between electrodes. The data was obtained and processed using software RES2DINV to get an image of the structure below the tuff ring into two dimensions. The results of data processing shown an image of resistivitas beneath the surface on the line 1. In general, it can be seen that the resistivitas beneath the surface line 1 is dominated by resistivitas more than 300 Ωm (purple colour image). Especially in meter 250-260 and meter 280-290, there are two zones with resistivitas value that is relatively small at less than 50 m. While on the line two, the resistivitas value is less than 60 Ωm (blue and green coloured zone ) that form patterns extend from the maximum depth to the surface, visible form a funnel/the cust from a depth of about 40 m (under electrodes to 18 or in meters to 90) To the surface (under electrodes 25 – 33 or in meters 125 -165) is directed to the northwest-southeast with the angle of inclination of about 40°42°and the resistivitas pattern elongated funnelshaped by contrast it also limited by the high resistivitas (> 300 Ωm) which is a structure with high density and less conductive. Which is interpreted as a former eruption channel preatomagmatic.
利用偶极-偶极组态地电方法,对马哈坞人工区凝灰岩环的地下结构进行了识别研究。它被分成两条线,每条线长480米,电极之间间隔10米,2号线长240米,电极之间间隔5米。利用RES2DINV软件获取数据并进行处理,得到凝灰岩环下结构的二维图像。数据处理的结果显示了1号线表面下的电阻率图像。一般情况下,可以看到地表1线以下的电阻率以300以上的电阻率为主Ωm(紫色图像)。特别是在250 ~ 260米和280 ~ 290米,在50m以下有两个电阻率值相对较小的区域。而在第二线上,电阻率值小于60 Ωm(蓝绿带),形成的图案从最大深度延伸到表面,可见形成漏斗/从深度约40米(电极下至18米或在米至90米)到表面(电极下25 - 33米或在米125 -165米)被引导到西北-东南,倾角约为40°42°,电阻率模式拉长漏斗形相比之下,它也受到高电阻率(> 300 Ωm)的限制,这是一个高密度和低导电性的结构。这被解释为一个前喷发通道。
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引用次数: 0
Investigasi Patahan Manado di Pesisir Teluk Manado Sebagai Upaya Mitigasi Bencana Alam 调查马纳多湾海岸的马纳多断层试图减轻自然灾害
Pub Date : 2020-12-12 DOI: 10.35799/JMUO.10.1.2021.31483
As'ari As'ari, S. H. Tongkukut, Sarmaria Panjaitan, I. A. Akasi, Meidy Rosalie Pulu
Daerah sumber gempa bumi biasanya terdapat pada patahan-patahan yang aktif dan daerah batas lempeng. Data sumber gempa dibutuhkan sebagai bahan evaluasi potensi bencana alam gempa bumi. Sulawesi Utara merupakan daerah yang mempunyai posisi dekat dengan pertemuan tiga lempeng, yaitu Lempeng Pasifik, Lempeng Eurasia dan Lempeng Indo Australia. Patahan Manado merupakan satu patahan yang terdapat di Sulawesi Utara melewati Kota Manado. Keberadaan patahan di pesisir Kota Manado memerlukan identifikasi lebih lanjut menggunakan survei geofisika bawah permukaan. Penelitian bertujuan mengidentifikasi parameter fisis patahan di Pesisir pantai Kota Manado. Eksplorasi dilakukan menggunakan metode geolistrik tahanan jenis konfigurasi dipol-dipol. Data diolah dengan menggunakan perangkat lunak Res2dinv, dan dihasilkan tampang lintang resistivitas 2 dimensi bawah permukaan bumi. Pada lintasan 1 yang terletak di reklamasi pantai, Patahan Manado diidentifikasi sebagai rekahan dengan nilai resistivitas ρ ≤ 20 Ωm, lebar patahan 10-60 m dan kedalaman sampai 20 m. Pada lintasan 2 yang terletak di daratan rekahan dengan nilai resistivitas ≤ 128 Ωm, lebar patahan 10-40 m dan kedalaman sampai 20 m. Rekahan pada lintasan 1 terisi material yang mengandung air laut, sedang rekahan pada lintasan 2 terisi material yang mengandung air tawar. Akuifer air tawar di daratan pesisir pada jalur patahan tidak terintrusi oleh air lautThe source areas for earthquakes are usually at active faults and plate boundary areas. Earthquake source data are needed as material for evaluate the potentiation of earthquake natural disaster. North Sulawesi is an area that has a position close to the meeting point of three plates, namely the Pacific Plate, Eurasian Plate and the Indo-Australian Plate. The Manado Fault is a fault located in North Sulawesi through the city of Manado. The existence of the fault on the coast of Manado City requires further identification using subsurface geophysical surveys. This study aims to identify the physical parameters of the fault on the coast of Manado City. Exploration is carried out using the geoelectric resistivity method of dipole-dipole configuration. The data is processed using Res2dinv software, and the result is a 2-dimensional resistivity cross section of the earth subsurface. On line 1 which is located at beach reclamation, the Manado Fault is identified as a fracture with a resistivity value of ρ ≤ 20 Ωm, a fault width of 10-60 m and a depth of up to 20 m. On line 2 which is located on the fracture land with a resistivity value ρ ≤ 128 Ωm, the fault width is 10-40 m and a depth of up to 20 m. The fracture on track 1 is filled with material containing sea water, while the fracture on line 2 is filled with material containing fresh water. Freshwater aquifers in coastal land on the fault line are not intruded by sea water
地震的源头通常是活跃的断层和板块边界。需要地震源数据作为评估地震潜在灾害的材料。北苏拉威西是一个靠近太平洋板块、欧亚大陆板块和印多澳大利亚板块三种板块汇合的地区。马纳多断裂带是北苏拉威西穿过马纳多镇的断裂带。马纳多市海岸的断层大陆的存在需要使用地下地球物理调查进行进一步的鉴定。研究的目的是确定马纳多市海岸的裂变参数。探索是使用二极管配置类型的犯人胃胃法进行的。数据通过Res2dinv软件进行分析,并生成地球表面下二维电阻率的可见率。位于海滩开垦的轨迹1ρ视电阻率值的身份,马纳多断层破裂断层≤20Ω英尺,宽10 - 60米深度,直到警官20米(66英尺)。位于大陆破裂的轨迹2≤128Ω视电阻率值m,宽10-40断层和深度到20米(66英尺)。1号跑道的断裂含海水的物质,2号跑道的破裂含淡水的物质。沿海沿海的淡水蓄水层不受地震源的影响。《地球地震》的数据来源需要美国的材料来评估自然灾害的潜力。北苏拉威西是一个区域,它的会议地点接近三个盘子,namely太平洋盘子,欧亚餐盘和印裔澳大利亚盘子。在马纳多镇的北苏拉威西发生的错误。在马纳多市灌溉的海岸上存在的疾病,使用地球探测潜艇。这项研究提供了马纳多市海岸疾病的物理参数。探索是用地理电阻的比喻来实现的。数据正在使用re2dinv软件,结果显示是地球地下部分的二维电阻。1,这是定位在海滩reclamation上线,《美国马纳多断层是identified a和a resistivity fracture value ofρ≤20Ωm, a 10 - 60米和警官的断层教室到20米(66英尺的深度。2,这是定位》上线fracture land with a resistivity价值ρ≤128Ω,断层的教室是10-40 m和a的深度取决于20米(66英尺)。第一行的框架充满了污染海洋的材料,而第2行的框架充满了污染新鲜水的材料。沿海水域的新水水务不受污染
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引用次数: 0
Rancang Bangun Alat Pengontrol Tingkat Pencahayaan Lampu Berbasis Mikrokontroler dengan Menggunakan Logika Fuzzy 用模糊的逻辑设计一个基于微控制器的光照明电平控制器
Pub Date : 2020-11-28 DOI: 10.35799/JMUO.10.1.2021.31387
Rirchard Christian Telleng, V. Suoth, H. Kolibu
Lampu adalah sumber cahaya buatan yang digunakan untuk membantu aktivitas manusia dan merupakan salah satu alat yang mengkonsumsi daya listrik terbanyak. Pencahayaan lampu pada saat ini hanya dikontrol secara manual dengan dua keadaan yang tentunya kurang efisien. Pengontrolan intensitas cahaya secara otomatis mampu meningkatkan efisiensi penggunaan lampu dari segi energi maupun pada pencahayaan agar mengikuti standar. Penelitian ini menggunakan sensor LDR sebagai pendeteksi cahaya, sensor ultrasonik (HC-SR04) sebagai pendeteksi jarak dan IC LM317 untuk mengatur tegangan. Logika fuzzy digunakan sebagai pengontrol intensitas cahaya yang diprogram ke modul Arduino Uno R3. Komponen ini disatukan dalam ruangan kecil yang berukuran 30 x 30 x 30 cm sebagai prototipe. Hasil penelitian menunjukkan bahwa sistem mampu mengatur pencahayaan ruangan sesuai SNI 03-6575-2001 dan dapat mendeteksi keluar-masuknya orang di ruangan. Perbandingan konsumsi daya selama 4 jam antara lampu dengan sistem dan yang tidak adalah sebesar 0.008027 kWH atau sekitar 57.21% dari daya yang dikonsumsi secara keseluruhan.Lamp is an light source that is used to assist humans and its one of the device that consumes a lot of electric power. Lighting lamps at this time only controlled manually with two conditions which is certainly less efficient. Controlling the intensity of the light automatically can increase the efficiency of used energy and lighting to follow the standards. This research uses the LDR sensor as a light detector, ultrasonic sensor (HC-SR04) as a proximity sensor and LM317 IC to regulate the voltage. Fuzzy logic is used to control the light intensity which programmed into the Arduino Uno R3 module. These components are put together in a small room with a length = 30, width = 30 and height = 30 cm as a prototype. The results show that the system is able to regulate room lighting according to SNI 03-6575-2001 and can detect if people moving in and out of the room. The comparison of power consumption for 4 hours between lights that are connected with the system and without connection is equal to 0.008027 kWH or about 57.21% of the total power consuming.
电灯是一种人造光源,用于帮助人类活动,是消耗电力最多的设备之一。目前的照明只能手动控制,在两种情况下,效率显然较低。自动对光强度的控制可以提高灯泡在能源和照明方面的使用效率,以符合标准。这项研究使用LDR传感器作为光探测器,超声波传感器(HC-SR04)作为接近感测器和IC LM317来调节电压。模糊逻辑是用来编程到Arduino Uno R3模块的光强度控制器。这些部件被组装在一个30×30×30厘米的小房间里作为原型。研究结果表明,该系统能够根据SNI 03-6575-2001调整房间灯光,并检测房间里的人的进进出出。光与系统之间4小时的能量消耗比为0.008027 kWH,约为57.21%的总耗电量。灯是一种光的来源,它用来帮助人类,它是一种可以产生很多电的装置。这次照明只由两种条件控制,这些条件当然不方便。控制光是自动的强度可以增加跟着标准使用的能量和光线的效率。这项研究研究了LDR传感器的位置,即a光探测器、超弦传感器(HC-SR04),以及用于调节电压的LM317 IC。模糊的逻辑用来控制设计成Arduino的强度R3模块。这些公司被放在一个很小的房间里,房间里有30个长度,宽度是30厘米,高度是原型。推荐节目显示,系统可以在SNI 03-6575-2001灯光下照明,并可以检测人们是否在房间里走动。综合电力消耗4个小时之间的系统连接和无连接等于0.008027 kWH或57.21%的总消耗。
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引用次数: 2
Analisis Keanekaragaman Lamun Di Pesisir Pulau Karakelang Kabupaten Kepulauan Talaud Sulawesi Utara
Pub Date : 2020-11-18 DOI: 10.35799/JMUO.10.1.2021.31297
Pience V. Maabuat, Marnix L. D. Langoy
Karakelang Seagrass Talaud Biodiversity Tabang Talaud Islands Regency is one of the administrative areas of North Sulawesi Province which is actively carrying out development in almost all fields, especially tourism. The area, which is a cluster of large islands, namely the islands of Karakelang, Salibabu, Nanusa and Mangaran, has high potential regarding biodiversity, especially marine biota. One example is the existence of biologically and ecologically supported types of seagrass on the coasts of almost all islands, however information regarding the types of seagrass in Talaud has not been fully recorded and is still scanty. For this reason, this study was conducted to determine the types of seagrass that are scattered on the coast of Karakelang Island. This research is also important to do in addition to providing information as a data base, it can also be used as a basis for decision making as an effort to conserve marine resources and waters. The method used is the quadratic transect method and each seagrass in the 1m x 1m square plot will be identified using a seagrass identification book. Diversity data analysis used the Shannon-wienner formula. The results obtained 7 (seven) types of seagrass, namely
塔邦塔劳德群岛摄政区是北苏拉威西省的行政区域之一,它正在积极开展几乎所有领域的发展,特别是旅游业。该地区是一群大岛,即卡拉基朗岛、萨利巴布岛、纳努萨岛和曼加兰岛,在生物多样性,特别是海洋生物群方面具有很高的潜力。一个例子是在几乎所有岛屿的海岸上都存在生物和生态支持的海草种类,但是关于塔劳德海草种类的资料没有得到充分记录,而且仍然很少。因此,本研究旨在确定散布在卡拉克朗岛海岸的海草类型。这项研究除了提供作为数据库的信息外,也很重要,它还可以作为决策的基础,以努力保护海洋资源和水域。使用的方法是二次样条法,使用海草鉴定书对1m × 1m方形地块中的每棵海草进行鉴定。多样性数据分析采用香农-维纳公式。结果得到7(7)种海草,分别为
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引用次数: 1
Pengaruh Transesterifikasi Minyak Kepala Ikan Tuna (Thunnus Albacares) Menggunakan Pereaksi Metanol dan Etanol 金枪鱼头油的转化作用使用甲醇和乙醇
Pub Date : 2020-11-09 DOI: 10.35799/JMUO.10.1.2021.31201
Meyffi Merrylin Jacobus, Julius Pontoh, Audy D. Wuntu
Transesterification Fatty acids Tuna (Thunnus albacares) Research on the effect of the transesterification method of tuna fish head oil (Thunnus albacares) using methanol and ethanol reagent has been carried out. The purpose of this study was to determine the effect of methanol and ethanol reagents on the transesterification process. The research methodology used in the transesterification of tuna fish oil (Thunnus albacares) is by using two alkyl source reactants, namely methanol and ethanol where the fatty acid alkyl esters were analyzed by gas chromatography. Transesterification using methanol reagent was carried out with BF3 acid catalyst and ethanol reagent was carried out with alkaline NaOH and KOH catalysts. The results showed that the main fatty acid content in fish oil in tuna's head was DHA, palmitate and linoleic. Transesterification of fish oil using acid (BF3 and methanol) and alkaline (NaOH and ethanol) methods resulted in the slightly different of fatty acid composition. DHA fatty acid has the highest content in ethanol reagent with KOH catalyst, namely (33.55%). Palmitic fatty acid (23.09%) was higher in the ethanol reagent with NaOH catalyst. And linolelaidic fatty acid was higher in transesterification using methanol reagent with BF3 catalyst, namely (20.98%).
采用甲醇和乙醇试剂对金枪鱼鱼头油进行酯交换反应,研究了酯交换法对金枪鱼鱼头油的影响。本研究的目的是确定甲醇和乙醇试剂对酯交换过程的影响。金枪鱼鱼油酯交换反应的研究方法是采用甲醇和乙醇两种烷基源反应物,用气相色谱法分析脂肪酸烷基酯。用甲醇试剂与BF3酸催化剂进行酯交换,用乙醇试剂与碱性NaOH和KOH催化剂进行酯交换。结果表明,金枪鱼头鱼油中主要脂肪酸含量为DHA、棕榈酸酯和亚油酸。用酸法(BF3和甲醇)和碱法(NaOH和乙醇)对鱼油进行酯交换反应,脂肪酸组成略有不同。以KOH为催化剂的乙醇试剂中DHA脂肪酸含量最高,为(33.55%)。在NaOH催化剂下,棕榈脂肪酸在乙醇试剂中提取率较高,达23.09%。甲醇试剂在BF3催化剂下,亚油酸脂肪酸的酯交换率较高,为20.98%。
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引用次数: 0
Formulasi dan Uji In Vitro Nilai Sun Protecting Factor (SPF) Krim dari Cangkang Telur Ayam Ras
Pub Date : 2020-11-07 DOI: 10.35799/JMUO.10.1.2021.31188
Yusnita Usman, Rahmatullah Muin
Chicken Eggshell Cream Sunblock Stabilitas Fisik The potential of chicken eggshell waste in Indonesia is quite large, which is produced + 133.703 every years. The main constituent of this shell is 98% of calcium carbonate (CaCO3) which functions to block ultraviolet light that will be exposed to the skin. This study aims to make a formula and determine the sun protecting factor (SPF) by in vitro test of cream from waste of this eggshells. The formula was made with difference concetration of this eggshell F1 (10%) and F2 (15%). Then the evaluation of physical characteristics includes organoleptic test, emulsion type, creaming, viscosity and pH as well as phase inversion before and after the accelerated condition for 10 cycles. Furthermore, the SPF was determined using a UV-VIS spectrophotometer at a wavelength of 290-320 nm and the measurement results were calculated using the SPF formula. The data from the evaluation of the physical stability of the cream were analyzed using SPSS with a partial T test with a confidence level of 95% and the significance was considered significant if P <0.05. Meanwhile, the SPF value was analyzed based on the sunscreen protection category. The results showed that F1 and F2 had adequate physical stability. The SPF value test results are CT 7500; CT 9000, F1 and F2 showed no difference in the UV protection category. All groups showed extra category protective UV activity
印尼的鸡蛋壳废弃物潜力相当大,每年产生+ 133.703个。这个外壳的主要成分是98%的碳酸钙(CaCO3),它的功能是阻挡暴露在皮肤上的紫外线。本研究的目的是通过体外试验,从这种蛋壳的废料中提取面霜,制备配方并确定其防晒系数(SPF)。以该蛋壳的不同浓度F1(10%)和F2(15%)配制配方。然后对物理特性的评价包括感官测试、乳液类型、乳化、粘度、pH值以及加速10个循环前后的相反转。采用紫外-可见分光光度计在290 ~ 320 nm波长范围内测定SPF值,并根据SPF公式计算测量结果。乳膏物理稳定性评价数据采用SPSS进行分析,采用部分T检验,置信水平为95%,以P <0.05为显著性。同时,根据防晒霜的防护类别对SPF值进行分析。结果表明,F1和F2具有良好的物理稳定性。SPF值测试结果为CT 7500;ct9000、F1和F2在紫外线防护类别上没有差异。所有组均显示出额外类别的紫外线保护活性
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引用次数: 0
Perbandingan Profil Penetrasi Formula Krim Antioksidan dari Ekstrak Perikarpium Buah Manggis (Garcinia mangostana) dengan Variasi Penetration Enhancer
Pub Date : 2020-10-29 DOI: 10.35799/JMUO.10.1.2021.31146
J. P. Siampa, J. S. Lebang, Irma Antasionasti, N. Nurmiati
Garcinia mangostana Penetration enhancer Antioxidant cream Sun exposure with UV radiation is one of the triggers for free radicals that cause premature aging (photoaging), characterized by hyperpigmentation, wrinkles, and decreased skin elasticity. The solution to this problem is the use of antioxidants that can prevent the formation of free radicals. The purpose of this study was to formulate an antioxidant cream dosage form from pericarpium extract of mangosteen pericarpium with different penetration enhancers to obtain the best percentage of penetration and retention in the skin. Pericarpium extract of mangosteen fruit was prepared by maceration method using 70% ethanol, then the antioxidant activity and the phenolic content were measured and were used as an active ingredient in the cream formula. Formula F1-F3 were made, their physical characteristics were evaluated, and in vitro penetration testing was carried out. In vitro penetration testing was carried out on F2 and F3 containing extracts. The IC50 value of the extract against DPPH was found to be 7.514 μg/mL and the phenolic content was found to be 112,70 ± 0,80 mgGAE/g. The percentage of penetration, retention percentage, and flux value were 9.96% ± 0.075%, 37.951% ± 0.103%, 3.037 ± 0.023 μg/cm2.hour respectively for F2 and 7.872% ± 0.078% , 33.874% ± 0.259%, 2.400 ± 0.024 μg/cm2.hour, respectively for F3. From the results of statistical analysis, it was concluded that F2 was the best formula with homogeneous physical characteristics, had a yellowish color, emulsion type w/o, pH value of 6, adhesion of 11.05 ± 0.87 seconds, and diameter of spreadability of 6.20 ± 0.10 cm.
紫外线辐射的阳光照射是自由基的触发因素之一,导致过早衰老(光老化),其特征是色素沉着、皱纹和皮肤弹性下降。解决这个问题的方法是使用抗氧化剂,它可以防止自由基的形成。以山竹果皮提取物为原料,加入不同的促渗剂,制备抗氧化乳膏剂型,以获得最佳的渗透率和皮肤滞留率。采用70%乙醇浸渍法制备山竹果皮提取物,测定其抗氧化活性和酚类物质含量,并将其作为乳膏配方的有效成分。配制F1-F3配方,评价其物理特性,并进行体外渗透试验。对含提取物的F2和F3进行体外渗透试验。提取物对DPPH的IC50值为7.514 μg/mL,酚含量为112,70±0,80 mgGAE/g。渗透率、滞留率、通量值分别为9.96%±0.075%、37.951%±0.103%、3.037±0.023 μg/cm2。F2分别为7.872%±0.078%、33.874%±0.259%、2.400±0.024 μg/cm2。小时,分别为F3。统计分析结果表明,F2为最佳配方,其物理特性均匀,颜色偏黄,乳液型w/o, pH值为6,粘附时间为11.05±0.87秒,涂胶直径为6.20±0.10 cm。
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引用次数: 2
Analisis Perencanaan Dan Pengadaan Obat Antibiotik Berdasarkan Metode ABC Indeks Kritis Di Instalasi Farmasi Rumah Sakit Advent Manado 根据基督复马纳多医院药厂关键成分ABC索引方法,规划和抗生素采购分析
Pub Date : 2020-10-12 DOI: 10.35799/JMUO.10.1.2021.30639
W. Lolo, Weny Indayany Widodo, D. A. Mpila
Perencanaan dan pengadaan obat merupakan salah satu fungsi penting dalam tahapan manajemen logistik obat, termasuk  obat antibiotik.  Sistem pengelolaan yang baik akan menjamin tersedianya obat sesuai dengan kebutuhan pasien.  Analisis ABC Indeks Kritis dapat digunakan untuk menentukan prioritas obat yang akan diadakan.  Penelitian ini bertujuan untuk menganalisis perencanaan dan pengadaan obat antibiotik di Instalasi Farmasi Rumah Sakit Advent Manado menggunakan analisis ABC Indeks Kritis.  Penelitian ini merupakan penelitian deskriptif kuantitatif.  Data primer diperoleh dari 8 orang responden yang mengisi kuesioner dan data sekunder diperoleh dari Instalasi Farmasi, Bagian Logistik dan Bagian Keuangan.  Data yang diperoleh dianalisis dengan metode ABC Indeks Kritis.  Hasil penelitian menunjukkan bahwa dari total 63 item obat antibiotik, 6 item merupakan kelompok A (9,52%), 29 item merupakan kelompok B (46,03%), dan 28 item merupakan kelompok C (44,44%).  Metode ABC Indeks Kritis dapat membantu rumah sakit dalam melakukan perencanaan dan pengadaan obat secara efisien dengan mempertimbangkan nilai pakai, nilai investasi dan nilai kritis obat.Drug planning and procurement is one of the most important function in steps of logistics management, include antibiotic drugs. A good management system will ensure the medical availability of drugs according to patient needs. The ABC critical index analysis can be used to prioritize drug procurement. This study aim to analyze the planning and procurement of antibiotic drugs in Pharmacy Installation at Manado Adventist Hospital by using ABC critical index analysis. The design of this research was quantitative descriptive study. Primary data were obtained from 8 respondents who filled the questionnaires; and secondary data were obtained from Pharmacy Installation, Logistic Division and Finance Division. Data were analyzed with ABC critical index method. The result of ABC critical index analysis showed that 63 antibiotic drug items were found, respectively, amounting for 6 (9.52%), 29 (46.03%) and 28 (44.44%) of drug items were found to be category A, B and C items. ABC critical index method can help hospital drug management in order to planning and procurement the drug efficiently by considering the use value, investment value, and critical value of drug.
药物规划和采购是包括抗生素在内的药物物流管理阶段的重要功能之一。良好的管理制度将确保病人的药物供应。关键指数ABC分析可以用来确定药物的优先级。这项研究的目的是利用关键指数ABC分析,分析基督复马纳多医院制药公司的抗生素开发和采购。这是一种定量描述性研究。主要数据来自8名受访者,他们填写调查问卷,从制药、物流和财务部获得辅助数据。所获得的数据是用ABC索引方法批判性分析的。研究表明,在总共63种抗生素药物中,6种是A组(9.52%),29种是B组(46.03%),28种是C组(44.44%)。ABC索引方法可以通过考虑药物的使用价值、投资价值和药物的批判性价值,帮助医院有效地规划和采购。毒品策划和开发是机理管理步骤中最重要的功能之一,包括抗生素药物。一个好的管理系统将确保药物对患者的需求的医疗应用。ABC critical指数分析可以用于优先毒品。这项研究旨在用ABC critical指数分析来分析马纳多Adventist Pharmacy instation和procution的抗生物药物。这个研究的设计是量化研究。主要来自8个回答问题的人;这两个数据来自Pharmacy Installation, Logistic Division和Finance司。数据是用ABC critical指数方法分析的。ABC分析报告显示,63种抗生物药物被发现为6(9.52%)、29(46.03%)和28(44.44%)而充血。ABC准则索引方法可以帮助医院的药物管理,这些药物考虑到使用价值、投资价值和价值毒品。
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引用次数: 3
Hubungan Persepsi Siswa Terhadap Keterampilan Guru Mengajar dan Kesiapan Belajar Dengan Hasil Belajar Matematika Siswa Kelas X IPS SMAN 7 Manado 学生对教师技能教学能力和学习准备能力的感知与学习数学学生IPS SMAN 7 Manado的结果的关系
Pub Date : 2020-10-03 DOI: 10.35799/JMUO.10.1.2021.30538
Yolanda Margareta Ambarita, J. Kekenusa, Luther A Latumakulita
Pendidikan merupakan komponen yang penting dalam pembangunan suatu negara. Dalam upaya pembangunan pendidikan diperlukan kebijakan yang disesuaikan dengan karakteristik suatu wilayah. Tujuan penelitian ini adalah memetakan Kabupaten/Kota yang memiliki kemiripan berdasarkan beberapa variabel pendidikan juga mengetahui korelasi antar variabel pendidikan dengan menggunakan analisis biplot. Data yang digunakan adalah data sekunder tahun 2018 yang diperoleh dari Badan Pusat Statistik (BPS) Provinsi Sulawesi Utara dan Kementerian Pendidikan dan Kebudayaan. Hasil dari analisis biplot penelitian ini menunjukkan bahwa Kabupaten/Kota yang memiliki karakteristik pendidikan yang relatif sama yaitu Kepulauan Sangihe, Kabupaten Minahasa Tenggara, dan Kabupaten Siau Tagulandang Biaro. Dimana keragaman yang terbesar terjadi pada jumlah SMP/sederajat, dan keunggulan dari suatu objek terdapat pada Kabupaten Bolaang Mongondow Utara memiliki nilai tertinggi pada variabel Angka Partisipasi Kasar (APK) SMP/sederajat. Kemudian variabel - variabel yang memiliki korelasi positif yaitu Angka Partisipasi Kasar (APK) SD/sederajat dan Angka Partisipasi Murni (APM) SD/sederajat yang artinya jika nilai Angka Partisipasi Kasar (APK) SD/sederajat bertambah, maka bertambah pula nilai Angka Partisipasi Murni (APM) SD/sederajat begitu juga sebaliknyaMathematics is one of the subjects that is taught in every educational stage, yet the fact shows that mathematics remains the one subject feared by students, and this condition can affect the students’ learning outcome. One of the factors which affects the learning outcome is the teacher’s teaching skill, which does not only involve their skill in a particular field, but also their creativity in developing that occupied field as well as their readiness to learn, where this will form the first step in initiating the teaching and learning activity. So this study was conducted to find out the relationship of the teacher’s teaching skill and readiness to learn with the mathematics learning outcome in class X IPS SMAN 7 Manado, using the Chi-Square test. The Chi-Square test is used to determine the relationship of a dependent variable with an independent variable, depending on a nominal or ordinal scale. This research has shown that there is no significant relationship between the teacher’s teaching skill and readiness to learn with the students’ learning outcome (p < 0,05)
教育是一个国家发展的重要组成部分。在教育建设工作中,需要符合某一地区特征的政策。本研究的目的是通过绘图分析确定基于多个教育变量的区域/城市匹配,同时了解教育变量之间的相关性。2018年是次要数据使用的数据来自机构统计中心(BPS)北苏拉威西省教育部和文化。这项研究的地图学分析表明,该地区与桑吉岛、米纳哈萨东南部和Tagulandang Biaro地区有着相对相同的教育特征。在初中/同等数量中,最大的多样性是在北博拉朗角地区发现的物体的优势,在粗参与率(APK)初中/同等分数上的得分最高。然后-积极的变量有相关性,即数字变量粗鲁(APK) SD -平等参与和纯数字参与平等(APM) SD -也就是说,如果数值粗鲁(APK) SD -平等参与的增长,那么怎样平等参与纯数值(APM) SD / subjects sebaliknyaMathematics是一号》也就是教在每一个教育阶段,然而《一号的节目那数学的遗迹feared科目由学生,这可能会影响学生的学习成果。《factors哪种.影响学习的一个结果是做老师的教导,哪种技能不仅牵扯到他们的技能在一个社会现场,但他们也creativity in developing那occupied陆军as well as readiness要学的,这在《第一站在initiating威尔没有注明教导和学习活动。因此,这项研究的目的是通过使用chi square测试,发现与教师的教学技能和活力来学习与数学的学习成果。中国广场测试用来确定与独立变量的可变可变的可变关系,取决于天平的大小。这项研究表明,教师的教学技能和学习成果之间没有意义。
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