Pub Date : 2020-09-29DOI: 10.35799/JMUO.10.1.2021.30416
Regina Octavia Marta Pogalin, Charles E. Mongi, N. Nainggolan
Biplot Analysis Singular Value Decomposition Education is an important component of country development. To educational development, the regulation which is adaptable to characteristics of a region is required. The purposes of this research are to implement the biplot analysis method to mapping Districts that have similar characteristics based on the educational variable and knowing the correlation between educational variables. This research used secondary data obtained from the North Sulawesi Central Statistics Agency (BPS) and the Ministry of Education and Culture. The results from biplot analysis showed that Sangihe Island Regency, Southeast Minahasa Regency, Siau Tagulandang Biaro Regency has similar characteristics, the number of junior high school has the biggest variance, Bolaang Mongondow Utara has the biggest value in Gross Enrollment Ratio (GER) Junior High School, Gross Enrollment Ratio (GER) Elementary School and Net Enrollment Ratio (NER) Elementary School has positive correlations, it means when one variable decreases as the other variable decreases or one variable increases while the other increases
{"title":"Analisis Biplot Untuk Pemetaan Kabupaten/Kota di Provinsi Sulawesi Utara Berdasarkan Beberapa Variabel Pendidikan","authors":"Regina Octavia Marta Pogalin, Charles E. Mongi, N. Nainggolan","doi":"10.35799/JMUO.10.1.2021.30416","DOIUrl":"https://doi.org/10.35799/JMUO.10.1.2021.30416","url":null,"abstract":"Biplot Analysis Singular Value Decomposition Education is an important component of country development. To educational development, the regulation which is adaptable to characteristics of a region is required. The purposes of this research are to implement the biplot analysis method to mapping Districts that have similar characteristics based on the educational variable and knowing the correlation between educational variables. This research used secondary data obtained from the North Sulawesi Central Statistics Agency (BPS) and the Ministry of Education and Culture. The results from biplot analysis showed that Sangihe Island Regency, Southeast Minahasa Regency, Siau Tagulandang Biaro Regency has similar characteristics, the number of junior high school has the biggest variance, Bolaang Mongondow Utara has the biggest value in Gross Enrollment Ratio (GER) Junior High School, Gross Enrollment Ratio (GER) Elementary School and Net Enrollment Ratio (NER) Elementary School has positive correlations, it means when one variable decreases as the other variable decreases or one variable increases while the other increases","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89662262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-07DOI: 10.35799/JMUO.9.2.2020.29029
Clarita Maramis, Guntur Pasau, G. Tamuntuan
Percepatan tanah maksimum (Peak Ground Acceleration) Adalah salah satu parameter yang digunakan dalam mengestimasi tingkat kerusakan akibat goncangan gempa bumi. Lengan utara pulau Sulawesi merupakan salah satu bagian dari pulau Sulawesi yang sangat rentan terhadap gempa bumi. Tujuan penelitian ini adalah untuk mendapatkan peta sebaran nilai PGA di lengan utara Sulawesi berdasarkan perhitungan percepatan tanah dengan menggunakan metode Fukushima-Tanaka sebagai upaya mitigasi bencana. Hasil analisis nlai PGA menunjukkan bahwa daerah utara provinsi Gorontalo, sebelah timur provinsi Sulawesi Utara (laut Maluku) dan daerah Sulawesi Tengah (kota Palu) memiliki tingkat kerawanan yang tinggi terhadap bencana gempa bumiPeak Ground Acceleration Is one of the parameters used in estimating the level of damage due to earthquake shocks. The northern arm region of Sulawesi island is one part of the island of Sulawesi which is very vulnerable to earthquakes. The purpose of this study was to obtain a map of the distribution of PGA values in the north arm of Sulawesi based on ground acceleration calculations using the Fukushima-Tanaka and method as a disaster mitigation effort. The results of the PGA analysis showed that the northern area of Gorontalo province, east of North Sulawesi province (Maluku sea) and Central Sulawesi area (Palu city) had a high level of vulnerability to earthquake disasters.
{"title":"Analisis Percepatan Tanah Maksimum Akibat Adanya Gempa Bumi di Lengan Utara Pulau Sulawesi Menggunakan Metode Fukushima Tanaka","authors":"Clarita Maramis, Guntur Pasau, G. Tamuntuan","doi":"10.35799/JMUO.9.2.2020.29029","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.29029","url":null,"abstract":"Percepatan tanah maksimum (Peak Ground Acceleration) Adalah salah satu parameter yang digunakan dalam mengestimasi tingkat kerusakan akibat goncangan gempa bumi. Lengan utara pulau Sulawesi merupakan salah satu bagian dari pulau Sulawesi yang sangat rentan terhadap gempa bumi. Tujuan penelitian ini adalah untuk mendapatkan peta sebaran nilai PGA di lengan utara Sulawesi berdasarkan perhitungan percepatan tanah dengan menggunakan metode Fukushima-Tanaka sebagai upaya mitigasi bencana. Hasil analisis nlai PGA menunjukkan bahwa daerah utara provinsi Gorontalo, sebelah timur provinsi Sulawesi Utara (laut Maluku) dan daerah Sulawesi Tengah (kota Palu) memiliki tingkat kerawanan yang tinggi terhadap bencana gempa bumiPeak Ground Acceleration Is one of the parameters used in estimating the level of damage due to earthquake shocks. The northern arm region of Sulawesi island is one part of the island of Sulawesi which is very vulnerable to earthquakes. The purpose of this study was to obtain a map of the distribution of PGA values in the north arm of Sulawesi based on ground acceleration calculations using the Fukushima-Tanaka and method as a disaster mitigation effort. The results of the PGA analysis showed that the northern area of Gorontalo province, east of North Sulawesi province (Maluku sea) and Central Sulawesi area (Palu city) had a high level of vulnerability to earthquake disasters.","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73458337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-06DOI: 10.35799/JMUO.9.2.2020.29041
Varian Giovanni Padang, Edwin de Queljoe, K. L. Mansauda
Buah Pare (Momordica charantia L.) merupakan buah yang memiliki berbagai khasiat terapetik tapi belum diketahui efek samping apabila dikonsumsi secara berlebihan terhadap gangguan organ hepar. Tujuan penelitian ini untuk Mengetahui Pengaruh Efek Ekstrak Etanol Buah Pare pada Gambaran Histopatologi Organ hepar Tikus putih jantan galur wistar. Sampel diekstraksi menggunakan metode maserasi. Ekstrak yang diperoleh diberikan kepada 4 kelompok hewan uji dengan konsentrasi 0,100,200, dan 400mg/ml secara berturut-turut. Setelah 50 hari, organ hepar hewan uji diambil dan dibuat preparat histopatologi. Gambaran Histopatologi menunjukan sampel organ hepar perlakuan P(100) dosis 100 mg/mL terlihat fokus perlemakan, untuk perlakuan P(200) dosis 200 mg/mL terlihat perlemakan disertai dengan terjadinya nekrosis, juga terlihat munculnya sel regeneratif. Pada P(400) dosis 400 mg/mL munculnya perlemakan, nekrosis, kongesti venacentralis, juga terlihat tanda sel regeneratif. Hal ini menunjukkan bahwa penggunaan ekstrak buah pare dapat menyebabkan efek negative pada jaringan sampel organ hepar galur wistarBitter Melon (Momordica Charantia L) is a fruit that has a various of therapeutic properties. However, Consuming an excess amount af bitter melon may have an unknown side effects towards the human’s liver. The Purpose of this research is to determine the effect of histopathlogical picture of the liver in the male white rats of wistar strain. The sample was extracted by using the maceration method. The acquired extract was given to the four guinea pig with 0, 100, 200, and 400 mg/ml concentration consecutively. After 50 days, the guinea pig’s liver organ was taken to be tested, and histopathological preparations was made. Histopathological picture shows fats that was accumulated in the liver tissue of the liver that were given 100 mg/ml of P(100). For Treatment P(200) dose of 200 mg/ml was seen to be accompanied by fatty necrosis, also seen the appeareance of regenerative cells. At P(400) dose of 400 mg/ml the appearance of fat, necrosis, venacentral Congestion, also seen signs of regenerative cells. This shows that the use of bitter melon extract may cause a side/negative effect to the sampel’s hepatic tissue “galur wistar”
{"title":"Efek Pemberian Ekstrak Etanol Buah Pare (Momordica Charantia L.) Terhadap Gambaran Histopatologi Organ Hepar Pada Tikus Putih Jantan Galur Wistar (Rattus Novergicus L.)","authors":"Varian Giovanni Padang, Edwin de Queljoe, K. L. Mansauda","doi":"10.35799/JMUO.9.2.2020.29041","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.29041","url":null,"abstract":"Buah Pare (Momordica charantia L.) merupakan buah yang memiliki berbagai khasiat terapetik tapi belum diketahui efek samping apabila dikonsumsi secara berlebihan terhadap gangguan organ hepar. Tujuan penelitian ini untuk Mengetahui Pengaruh Efek Ekstrak Etanol Buah Pare pada Gambaran Histopatologi Organ hepar Tikus putih jantan galur wistar. Sampel diekstraksi menggunakan metode maserasi. Ekstrak yang diperoleh diberikan kepada 4 kelompok hewan uji dengan konsentrasi 0,100,200, dan 400mg/ml secara berturut-turut. Setelah 50 hari, organ hepar hewan uji diambil dan dibuat preparat histopatologi. Gambaran Histopatologi menunjukan sampel organ hepar perlakuan P(100) dosis 100 mg/mL terlihat fokus perlemakan, untuk perlakuan P(200) dosis 200 mg/mL terlihat perlemakan disertai dengan terjadinya nekrosis, juga terlihat munculnya sel regeneratif. Pada P(400) dosis 400 mg/mL munculnya perlemakan, nekrosis, kongesti venacentralis, juga terlihat tanda sel regeneratif. Hal ini menunjukkan bahwa penggunaan ekstrak buah pare dapat menyebabkan efek negative pada jaringan sampel organ hepar galur wistarBitter Melon (Momordica Charantia L) is a fruit that has a various of therapeutic properties. However, Consuming an excess amount af bitter melon may have an unknown side effects towards the human’s liver. The Purpose of this research is to determine the effect of histopathlogical picture of the liver in the male white rats of wistar strain. The sample was extracted by using the maceration method. The acquired extract was given to the four guinea pig with 0, 100, 200, and 400 mg/ml concentration consecutively. After 50 days, the guinea pig’s liver organ was taken to be tested, and histopathological preparations was made. Histopathological picture shows fats that was accumulated in the liver tissue of the liver that were given 100 mg/ml of P(100). For Treatment P(200) dose of 200 mg/ml was seen to be accompanied by fatty necrosis, also seen the appeareance of regenerative cells. At P(400) dose of 400 mg/ml the appearance of fat, necrosis, venacentral Congestion, also seen signs of regenerative cells. This shows that the use of bitter melon extract may cause a side/negative effect to the sampel’s hepatic tissue “galur wistar”","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77786226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-02DOI: 10.35799/JMUO.9.2.2020.29000
Trian Rizki Kala’ Rante, H. Simbala, K. Mansauda
Stachytarpheta jamaicensis L Phytochemical Screening Antioxidants DPPH. Ekor tikus (Stachytarpheta jamaicensis L.) are family of verbenaceae. Ekor tikus (Stachytarpheta jamaicensis L.) or pecut kuda, The aim of this study was determining the potential of the leaves of ekor tikus that growing in Tomohon city based on phytochemicals content and antioxsidant activities. The leaves of ekor tikus extract done extraction with using maceration terraced methods used n-heksan, ethyl acetate and ethanol 96%. Phytochemicals screening are used some reagent that 's adapted to type of phytochemical test. Dpph methods are used to evaluate the antioxidant activities. The results showed that n-hexane extract contained steroids, tannins and saponins, IC50 value of 19.76 μg / mL. Ethyl acetate extract has steroid and tannin content, IC50 value of 12.91 μg / mL. Ethanol extract contains alkaloids, flavonoids, triterpenoids, tannins and saponins, IC50 values 16.66 μg / mL.
{"title":"Skrining Fitokimia Dan Potensi Antioksidan Dari Ekstrak Daun Tumbuhan Ekor Tikus (Stachytarpheta jamaicensis L) Dengan Metode 1.1 Diphenyl-2-Picrylhydracyl (Dpph)","authors":"Trian Rizki Kala’ Rante, H. Simbala, K. Mansauda","doi":"10.35799/JMUO.9.2.2020.29000","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.29000","url":null,"abstract":"Stachytarpheta jamaicensis L Phytochemical Screening Antioxidants DPPH. Ekor tikus (Stachytarpheta jamaicensis L.) are family of verbenaceae. Ekor tikus (Stachytarpheta jamaicensis L.) or pecut kuda, The aim of this study was determining the potential of the leaves of ekor tikus that growing in Tomohon city based on phytochemicals content and antioxsidant activities. The leaves of ekor tikus extract done extraction with using maceration terraced methods used n-heksan, ethyl acetate and ethanol 96%. Phytochemicals screening are used some reagent that 's adapted to type of phytochemical test. Dpph methods are used to evaluate the antioxidant activities. The results showed that n-hexane extract contained steroids, tannins and saponins, IC50 value of 19.76 μg / mL. Ethyl acetate extract has steroid and tannin content, IC50 value of 12.91 μg / mL. Ethanol extract contains alkaloids, flavonoids, triterpenoids, tannins and saponins, IC50 values 16.66 μg / mL.","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76238370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-29DOI: 10.35799/JMUO.9.2.2020.28946
Vanesa Vebiola Kumakauw, H. Simbala, K. L. Mansauda
Sesewanua (Clerodendron squamatum Vahl.) secara empiris telah digunakan oleh masyarakat dibeberapa daerah di Sulawesi Utara untuk mengobati berbagai macam penyakit. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari ekstrak etanol daun sesewanua terhadap daya hambat pertumbuhan bakteri Staphylococcus aureus, Escherichia coli dan Salmonella typhi menggunakan tiga kosentrasi yakni 20%, 40% dan 60%. Ekstraksi dilakukan dengan cara maserasi menggunakan etanol 96%. Pengujian aktivitas antibakteri menggunakan metode difusi dengan cakram kertas (difusi Kirby dan Bauer). Hasil penelitian ini menunjukkan bahwa ekstrak etanol daun sesewanua berpotensi sebagai antibakteri dan memiliki kekuatan antibakteri terhadap Staphylococcus aureus, Escherichia coli dan Salmonella typhi, pada kosentrasi 20%, 40% dan 60% termasuk golongan kuat untuk menghambat bakteri Staphylococcus aureus, sedangkan pada kosentrasi 40% dan 60% termasuk dalam golongan kuat untuk menghambat bakteri Escherichia coli dan Salmonella typhi.Sesewanua (Clerodendron squamatum Vahl.) have been used by communities in North Sulawesi for to treat or handle various diseases. This study aims to determine the antibacterial activity from ethanol extract Sesewanua Leaves against the growth inhibition of the bacterium Staphylococcus aureus, Escherichia coli and Salmonella typhi using three concentrations of 20%, 40% and 60%. Extraction was done by maceration method using ethanol 96%. Antibacterial activity test was performing using the paper disk diffusion method (Kirby and Bauer diffusion). This results of this study indicate that ethanol extracts of Sesewanua leaves are considered as antibacterial and have antibacterial strength against Staphylococcus aureus, Escherichia coli and Salmonella typhi, at concentrations of 20%, 40% and 60% include strong groups to inhibit Staphylococcus aureus, while at a concentration of 40% and 60% include strong groups to inhibit Escherichia coli and Salmonella typhi.
Sesewanua (Clerodendron squamatum Vahl)曾被北苏拉威西几个地区的社区用过治疗各种疾病。该研究的目的是确定从葡萄球菌菌根、Escherichia大肠杆菌和沙门氏杆菌中提取出的抗菌活性，该菌以20%、40%和60%为中心。提取方法是用96%的乙醇进行的。利用柯比和鲍尔的文件扩散方法测试抗菌活性。这项研究结果表明,潜在sesewanua叶乙醇提取物作为杆菌抗菌抗菌和有能力对奥里斯,Escherichia大肠杆菌和沙门氏菌typhi在关注20%、40%和60%,包括阶级强大可以抑制细菌体内奥里斯,而在阶级强大关注40%和60%包括抑制细菌Escherichia大肠杆菌和沙门氏菌typhi。Sesewanua (clerodentum squamatum Vahl)曾被北苏拉威西社区用来治疗各种疾病。这项研究旨在确定来自乙醇extract sewanua的抗菌活性抑制，导致大肠杆菌、大肠杆菌和沙门氏菌的生长抑制，使用20%、40%和60%的三分流酶。用乙醇96%的方法进行的提取。防细菌活动测试是在纸盘离散方式上进行的。这个results of This study indicate that Sesewanua树叶是认为美国的乙醇摘录antibacterial和体内有antibacterial力量反对奥里斯,Escherichia大肠杆菌和沙门氏菌typhi, at concentrations of 20%、40%和60% include特朗集团杆菌inhibit奥里斯,而在百万双臀40%和60%的include特朗集团到inhibit Escherichia大肠杆菌和沙门氏菌typhi。
{"title":"Aktivitas Antibakteri Ekstrak Etanol Daun Sesewanua (Clerodendron Squamatum Vahl.) terhadap Bakteri Staphylococcus aureus Escherichia coli dan Salmonella typhi","authors":"Vanesa Vebiola Kumakauw, H. Simbala, K. L. Mansauda","doi":"10.35799/JMUO.9.2.2020.28946","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.28946","url":null,"abstract":"Sesewanua (Clerodendron squamatum Vahl.) secara empiris telah digunakan oleh masyarakat dibeberapa daerah di Sulawesi Utara untuk mengobati berbagai macam penyakit. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari ekstrak etanol daun sesewanua terhadap daya hambat pertumbuhan bakteri Staphylococcus aureus, Escherichia coli dan Salmonella typhi menggunakan tiga kosentrasi yakni 20%, 40% dan 60%. Ekstraksi dilakukan dengan cara maserasi menggunakan etanol 96%. Pengujian aktivitas antibakteri menggunakan metode difusi dengan cakram kertas (difusi Kirby dan Bauer). Hasil penelitian ini menunjukkan bahwa ekstrak etanol daun sesewanua berpotensi sebagai antibakteri dan memiliki kekuatan antibakteri terhadap Staphylococcus aureus, Escherichia coli dan Salmonella typhi, pada kosentrasi 20%, 40% dan 60% termasuk golongan kuat untuk menghambat bakteri Staphylococcus aureus, sedangkan pada kosentrasi 40% dan 60% termasuk dalam golongan kuat untuk menghambat bakteri Escherichia coli dan Salmonella typhi.Sesewanua (Clerodendron squamatum Vahl.) have been used by communities in North Sulawesi for to treat or handle various diseases. This study aims to determine the antibacterial activity from ethanol extract Sesewanua Leaves against the growth inhibition of the bacterium Staphylococcus aureus, Escherichia coli and Salmonella typhi using three concentrations of 20%, 40% and 60%. Extraction was done by maceration method using ethanol 96%. Antibacterial activity test was performing using the paper disk diffusion method (Kirby and Bauer diffusion). This results of this study indicate that ethanol extracts of Sesewanua leaves are considered as antibacterial and have antibacterial strength against Staphylococcus aureus, Escherichia coli and Salmonella typhi, at concentrations of 20%, 40% and 60% include strong groups to inhibit Staphylococcus aureus, while at a concentration of 40% and 60% include strong groups to inhibit Escherichia coli and Salmonella typhi.","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74673686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-26DOI: 10.35799/JMUO.9.2.2020.28925
J. Rombang, Hanny F. Sangian, Guntur Pasau, Jil Astriko Lametige
Tujuan dari penelitian ini adalah untuk melakukan studi bahan bakar campuran, etanol, diesel, dan biodiesel yang terbuat dari minyak kelapa sawit dan kelapa. Penelitian ini dilakukan untuk mengurangi penggunaan bahan bakar fosil dan pencemeran yang dihasilkannya. Biodiesel dibuat dengan menggunakan metode konvensional dan transesterifikasi subkritis dekat isokorik. Setelah disiapkan, biodiesel, diesel, dan etanol 96% dicampur. Sampel dianalisis menggunakan metode ASTM. Sampel 1b yang terdiri dari 69 % biodiesel memiliki densitas 0.886 , viskositas 5,182 , titik api 66 , titik tuang 6 . Sampel 2b yang mengandung 60 % biodiesel memiliki densitas 0,865 , viskositas 4,271 , titik api 65 , titik tuang 3 . Sampel 3b yang mengandung 72 % biodiesel memiliki densitas 0,878 , viskositas 5,350 , titik api 70 , titik tuang 0 . Sampel 4b yang terdiri atas 54 % biodiesel memiliki densitas 0,859 , viskositas 4,289 , titik api 56 , titik tuang 3 . Berdasarkan peraturan Pemerintah Indonesia tentang spesifikasi bahan bakar diesel, sampel 2b adalah campuran terbaik, sedangkan sampel 3b yang tidak sesuai dengan spesifikasi.The purpose of this study is to conduct a study of blended fuels, ethanol, diesel, and biodiesel prepared from palm and coconut oils. This research was conducted to reduce the usage of fossil fuels and its resulting pollution. Biodiesel was prepared using conventional method and near isochoric subcritical transesterification. After prepared, biodiesel, diesel, and 96% ethanol were mixed. The sample was analyzed using the ASTM method. Sample 1b which contains 69 % biodiesel has density 0.886 , viscosity 5.182 , flash point 66 , pour point 6 . Sample 2b containing 60 % biodiesel has density 0.865 , viscosity 4.271 , flash point 65 , pour point 3 . Sample 3b consisting 72 % biodiesel has density 0.878 , viscosity 5.350 , flash point 70 , pour point 0 . Sample 4b that contains 54 % biodiesel has density 0.859 , viscosity 4.289 , flash point 56 , pour point 3 . Based on the regulation of the Indonesia Government about diesel fuel specification, sample 2b is the best blends, while sample 3b is the least one.
{"title":"Studi Bahan Bakar Campuran Biodiesel-Disel-Etanol: Biodiesel Dibuat Dengan Transeterifikasi Tekanan Tinggi","authors":"J. Rombang, Hanny F. Sangian, Guntur Pasau, Jil Astriko Lametige","doi":"10.35799/JMUO.9.2.2020.28925","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.28925","url":null,"abstract":"Tujuan dari penelitian ini adalah untuk melakukan studi bahan bakar campuran, etanol, diesel, dan biodiesel yang terbuat dari minyak kelapa sawit dan kelapa. Penelitian ini dilakukan untuk mengurangi penggunaan bahan bakar fosil dan pencemeran yang dihasilkannya. Biodiesel dibuat dengan menggunakan metode konvensional dan transesterifikasi subkritis dekat isokorik. Setelah disiapkan, biodiesel, diesel, dan etanol 96% dicampur. Sampel dianalisis menggunakan metode ASTM. Sampel 1b yang terdiri dari 69 % biodiesel memiliki densitas 0.886 , viskositas 5,182 , titik api 66 , titik tuang 6 . Sampel 2b yang mengandung 60 % biodiesel memiliki densitas 0,865 , viskositas 4,271 , titik api 65 , titik tuang 3 . Sampel 3b yang mengandung 72 % biodiesel memiliki densitas 0,878 , viskositas 5,350 , titik api 70 , titik tuang 0 . Sampel 4b yang terdiri atas 54 % biodiesel memiliki densitas 0,859 , viskositas 4,289 , titik api 56 , titik tuang 3 . Berdasarkan peraturan Pemerintah Indonesia tentang spesifikasi bahan bakar diesel, sampel 2b adalah campuran terbaik, sedangkan sampel 3b yang tidak sesuai dengan spesifikasi.The purpose of this study is to conduct a study of blended fuels, ethanol, diesel, and biodiesel prepared from palm and coconut oils. This research was conducted to reduce the usage of fossil fuels and its resulting pollution. Biodiesel was prepared using conventional method and near isochoric subcritical transesterification. After prepared, biodiesel, diesel, and 96% ethanol were mixed. The sample was analyzed using the ASTM method. Sample 1b which contains 69 % biodiesel has density 0.886 , viscosity 5.182 , flash point 66 , pour point 6 . Sample 2b containing 60 % biodiesel has density 0.865 , viscosity 4.271 , flash point 65 , pour point 3 . Sample 3b consisting 72 % biodiesel has density 0.878 , viscosity 5.350 , flash point 70 , pour point 0 . Sample 4b that contains 54 % biodiesel has density 0.859 , viscosity 4.289 , flash point 56 , pour point 3 . Based on the regulation of the Indonesia Government about diesel fuel specification, sample 2b is the best blends, while sample 3b is the least one. ","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76838568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kerusakan gigi salah satunya adalah karies gigi yang di sebabkan oleh bakteri Streptococcus mutans. Buah sirih (Piper betle L) dapat di gunakan untuk tanaman obat karena memiliki kandungan senyawa tanin sebagai antibakteri. Tujuan penelitian untuk mengetahui kandungan senyawa tanin dan uji aktifitas antibakteri fraksi n-heksan, kloroform dan etil asetat terhadap bakteri Streptococcus mutans. Jenis penelitian ini ialah Deskriptif Analitik. Pengujian kandungan senyawa tanin secara kualitatif ekstrak buah sirih menggunakan kromatografi lapis tipis (KLT) dan spektrofotometer Uv-Vis serta pengujian antibakteri pada konsentrasi 3%, 4%, 5% dan 6% untuk masing-masing fraksi. Hasil penelitian menunjukan bahwa ketiga fraksi: n-heksan, kloroform dan etil asetat positif mengandung senyawa tanin. Pengujian antibakteri pada konsentrasi 3%, 4%, 5% dan 6% menunjukan adanya aktifitas antibakteri dari ketiga fraksi : n-heksan ,kloroform dan etil asetat terhadap bakteri Streptococcus mutans dengan daya hambat berturut-turut untuk fraksi n-heksan 12.883±0.510; 12.600±1.455; 13.916±2.877; 13.550±3.347, untuk fraksi kloroform 16.400±1.646; 16.450±1.053; 17.183±1.830; 17.916±1.338 dan fraksi etil asetat 16.400±1.200; 16.000±0.327; 16.850±1.253; 17.450±1.297. Sehingga dapat disimpulkan ekstrak buah sirih mengandung senyawa tanin dan ketiga fraksi n-heksan ,kloroform dan etil asetat memiliki aktifitas antibakteri terhadap Streptococcus mutans dengan kategori kuat.Tooth decay one of which is dental caries caused by Streptococcus mutans bacteria. Betel fruit (Piper betle L) can be used for medicinal plants because it contains tannin compounds as antibacterial. The purpose of this study was to determine the content of tannin compounds and test the antibacterial activity of the n-hexane, chloroform and ethyl acetate fractions against Streptococcus mutans. This type of research is Descriptive Analytic. Testing the content of tannin compounds qualitatively betel fruit extract using thin layer chromatography (TLC) and Uv-Vis spectrophotometer and antibacterial testing at concentrations of 3%, 4%, 5% and 6% for each fraction. The results showed that all three fractions: n-hexane, chloroform and ethyl acetate positively contained tannin compounds. Antibacterial testing at concentrations of 3%, 4%, 5% and 6% showed antibacterial activity of the three fractions: n-hexane, chloroform and ethyl acetate against Streptococcus mutans with inhibitions for the n-hexane fraction 12.883 ± 0.510; 12,600 ± 1,455; 13,916 ± 2,877; 13,550 ± 3,347, for the chloroform fraction 16,400 ± 1,646; 16,450 ± 1,053; 17,183 ± 1,830; 17,916 ± 1,338 and the ethyl acetate fraction 16,400 ± 1,200; 16,000 ± 0.327; 16,850 ± 1,253; 17,450 ± 1,297. So it can be concluded that betel fruit extract contains tannin compounds and the three fractions of n-hexane, chloroform and ethyl acetate have antibacterial activity against Streptococcus mutans with a strong category.
蛀牙的原因之一是链球菌引起的龋齿。槟榔可以用于药用植物，因为单宁酸作为抗菌物质。研究目的是确定丹宁化合物的含量，并测试对链球菌菌的n-heksan、氯仿和醋酸乙活性。这种研究是一种分析性描述性研究。测试甜菜提取物的性质性质单宁化合物(KLT)和Uv-Vis光谱仪，并对每个成分进行抗菌检测，其浓度为3%、4%、5%和6%。研究表明，n-heksan、氯仿和醋酸乙三种成分都含有单宁化合物。抗菌试验浓度3%、4%、5%和6%暗示第三的抗菌成分的活动:对链球菌细菌n-heksan,氯仿和醋酸纤维素乙醇mutans连续资源等等,以派别n-heksan 12883±0.510;12.600±1.455;13916±2.877;13.550±3347,氯仿成分的1.82美元±1.646;16.450±1.053;17.183±1830米;17916±1.338和醋酸纤维素乙醇成分1.82美元±1200;1.6±0.327;16.850±1.253;17450±1.297。因此，可以说甜菜提取物中含有单宁化合物和三种成分的n-heksan、氯仿和乙基对链球菌的抗菌活性具有强类别。牙齿的退化是由链球菌引起的牙齿。betle fruit (Piper betle)可以用于医疗植物，因为它是一种抗菌的上一品。这项研究的目的是确定n-hexane、氯仿和乙基对链球菌的影响的结果。这是研究的类型描述分析。测试上相结合的上相品品品品采用分光造影技术(TLC)和uv -相对光谱仪和抑制细菌学测试，以3%、4%、5%和6%的帧为中心。结果显示所有三个框架:n-hexane，氯仿和乙基积极参与今天的联合。Antibacterial测试at concentrations of 3%、4%、5%和6%那里Antibacterial活动《三个fractions:醋酸n-hexane,氯仿和乙基反对链球菌、和inhibitions for the mutans n-hexane fraction 12883±0.510;12,600±1,455;13,916±2,877;13,550±3,347,for the氯仿fraction 16,400±1,646;16,450±1,053;17,183±1830;醋酸17,916±1,338《乙基fraction 16,400±1200;16000±0.327;16,850±1,253;17,450±1,297。因此，它可以得出结论，上皮水果extract contact to the bethelites extract contact n-hexane，氯仿和乙酰乙胺的三种成分与强烈的链球菌抗杆菌反应。
{"title":"Analisis Senyawa Tannin Dan Aktifitas Antibakteri Fraksi Buah Sirih (Piper betle L) Terhadap Streptococcus mutans","authors":"Venila Makatambah, Fatimawali Fatimawali, Gerald Rundengan","doi":"10.35799/JMUO.9.2.2020.28922","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.28922","url":null,"abstract":"Kerusakan gigi salah satunya adalah karies gigi yang di sebabkan oleh bakteri Streptococcus mutans. Buah sirih (Piper betle L) dapat di gunakan untuk tanaman obat karena memiliki kandungan senyawa tanin sebagai antibakteri. Tujuan penelitian untuk mengetahui kandungan senyawa tanin dan uji aktifitas antibakteri fraksi n-heksan, kloroform dan etil asetat terhadap bakteri Streptococcus mutans. Jenis penelitian ini ialah Deskriptif Analitik. Pengujian kandungan senyawa tanin secara kualitatif ekstrak buah sirih menggunakan kromatografi lapis tipis (KLT) dan spektrofotometer Uv-Vis serta pengujian antibakteri pada konsentrasi 3%, 4%, 5% dan 6% untuk masing-masing fraksi. Hasil penelitian menunjukan bahwa ketiga fraksi: n-heksan, kloroform dan etil asetat positif mengandung senyawa tanin. Pengujian antibakteri pada konsentrasi 3%, 4%, 5% dan 6% menunjukan adanya aktifitas antibakteri dari ketiga fraksi : n-heksan ,kloroform dan etil asetat terhadap bakteri Streptococcus mutans dengan daya hambat berturut-turut untuk fraksi n-heksan 12.883±0.510; 12.600±1.455; 13.916±2.877; 13.550±3.347, untuk fraksi kloroform 16.400±1.646; 16.450±1.053; 17.183±1.830; 17.916±1.338 dan fraksi etil asetat 16.400±1.200; 16.000±0.327; 16.850±1.253; 17.450±1.297. Sehingga dapat disimpulkan ekstrak buah sirih mengandung senyawa tanin dan ketiga fraksi n-heksan ,kloroform dan etil asetat memiliki aktifitas antibakteri terhadap Streptococcus mutans dengan kategori kuat.Tooth decay one of which is dental caries caused by Streptococcus mutans bacteria. Betel fruit (Piper betle L) can be used for medicinal plants because it contains tannin compounds as antibacterial. The purpose of this study was to determine the content of tannin compounds and test the antibacterial activity of the n-hexane, chloroform and ethyl acetate fractions against Streptococcus mutans. This type of research is Descriptive Analytic. Testing the content of tannin compounds qualitatively betel fruit extract using thin layer chromatography (TLC) and Uv-Vis spectrophotometer and antibacterial testing at concentrations of 3%, 4%, 5% and 6% for each fraction. The results showed that all three fractions: n-hexane, chloroform and ethyl acetate positively contained tannin compounds. Antibacterial testing at concentrations of 3%, 4%, 5% and 6% showed antibacterial activity of the three fractions: n-hexane, chloroform and ethyl acetate against Streptococcus mutans with inhibitions for the n-hexane fraction 12.883 ± 0.510; 12,600 ± 1,455; 13,916 ± 2,877; 13,550 ± 3,347, for the chloroform fraction 16,400 ± 1,646; 16,450 ± 1,053; 17,183 ± 1,830; 17,916 ± 1,338 and the ethyl acetate fraction 16,400 ± 1,200; 16,000 ± 0.327; 16,850 ± 1,253; 17,450 ± 1,297. So it can be concluded that betel fruit extract contains tannin compounds and the three fractions of n-hexane, chloroform and ethyl acetate have antibacterial activity against Streptococcus mutans with a strong category.","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78967808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-23DOI: 10.35799/JMUO.9.2.2020.28893
Adelia S. Modeong, Roni Koneri, Farha N. J. Dapas
Nymphalidae merupakan famili yang memiliki jumlah spesies terbesar dibandingkan dengan famili lainnya. Kupu-kupu tersebut dalam suatu ekosistem memiliki peran yang penting yaitu sebagai polinator dalam penyerbukan, dan dapat dijadikan bioindikator lingkungan. Data kelimpahan dan keanekaragaman kupu-kupu Nymphalidae pada kawasan hutan Kuwil pada saat ini belum tersedia. Penelitian ini bertujuan untuk menganalisis kelimpahan dan keanekaragaman spesies kupu-kupu famili Nymphalidae di Hutan Kota Kuwil Minahasa Utara. Teknik pengambilan sampel menggunakan metode transek. Penempatan transek pada setiap habitat dilakukan secara Purposive Random Sampling. Tipe habitat pada lokasi penelitian adalah pinggir sungai, hutan dan kebun. Pengambilan sampel dilakukan sepanjang garis transek menggunakan sweepnet. Komposisi spesies Nymphaldae ditemukan sebanyak 21 spesies dan 208 individu. Spesies yang memiliki kelimpahan tertinggi adalah Parthenos shylvia dan Idea blnchardii. Analisis keanekaragaman didapatkan kelimpahan spesies Nymphalidae pada habitat pinggir sungai sebesar 101 individu, hutan 70 individu, dan kebun 37 individu. Indeks keanekargaman spesies di pinggir sungai 2,55, hutan 2,41 dan kebun 2,03. Indeks kekayaan spesies pinggir sungai 3,25, hutan 3,06 dan kebun 2,49. Indek kemerataan spesies pinggir sungai memiliki nilai yang sama dengan hutan yaitu sebesar 0,91, sedangkan pada kebun sebesar 0,88. Berdasarkan nilai tersebut didapatkan bahwa kelimpahan, indeks kekayaan dan indeks keanekaragaman spesies kupu-kupu Nymhalidae tertinggi ditemukan pada habitat pinggir sungaiNymphalidae is a family with the largest number of species compared to other families. This butterfly has an important role as a pollinator for pollination in an ecosystem, and can be used as an environmental bioindicator. Data on abundance and variation of Nymphalidae butterflies in the Kuwil forest area was not avilable. This study aims to analyze the abundance and species of Nymphalidae family butterflies in the Forest of the Northern Minahasa Region. The sampling technique that was used is the transect method. Transect placement in each habitat was done by Purposive Random Sampling. The habitat types at the study site are on the river banks, forests and gardens. Sampling was carried out along the transect line using sweepnet. The composition of the Nymphaldae species found was 21 species and 208 individuals. The species with have the highest abundance are Parthenos shylvia and Idea blnchardii. Diversity
{"title":"Kelimpahan dan Keanekaragaman Kupu-Kupu Nymphalidae di Hutan Kota Kuwil Minahasa Utara Sulawesi Utara","authors":"Adelia S. Modeong, Roni Koneri, Farha N. J. Dapas","doi":"10.35799/JMUO.9.2.2020.28893","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.28893","url":null,"abstract":"Nymphalidae merupakan famili yang memiliki jumlah spesies terbesar dibandingkan dengan famili lainnya. Kupu-kupu tersebut dalam suatu ekosistem memiliki peran yang penting yaitu sebagai polinator dalam penyerbukan, dan dapat dijadikan bioindikator lingkungan. Data kelimpahan dan keanekaragaman kupu-kupu Nymphalidae pada kawasan hutan Kuwil pada saat ini belum tersedia. Penelitian ini bertujuan untuk menganalisis kelimpahan dan keanekaragaman spesies kupu-kupu famili Nymphalidae di Hutan Kota Kuwil Minahasa Utara. Teknik pengambilan sampel menggunakan metode transek. Penempatan transek pada setiap habitat dilakukan secara Purposive Random Sampling. Tipe habitat pada lokasi penelitian adalah pinggir sungai, hutan dan kebun. Pengambilan sampel dilakukan sepanjang garis transek menggunakan sweepnet. Komposisi spesies Nymphaldae ditemukan sebanyak 21 spesies dan 208 individu. Spesies yang memiliki kelimpahan tertinggi adalah Parthenos shylvia dan Idea blnchardii. Analisis keanekaragaman didapatkan kelimpahan spesies Nymphalidae pada habitat pinggir sungai sebesar 101 individu, hutan 70 individu, dan kebun 37 individu. Indeks keanekargaman spesies di pinggir sungai 2,55, hutan 2,41 dan kebun 2,03. Indeks kekayaan spesies pinggir sungai 3,25, hutan 3,06 dan kebun 2,49. Indek kemerataan spesies pinggir sungai memiliki nilai yang sama dengan hutan yaitu sebesar 0,91, sedangkan pada kebun sebesar 0,88. Berdasarkan nilai tersebut didapatkan bahwa kelimpahan, indeks kekayaan dan indeks keanekaragaman spesies kupu-kupu Nymhalidae tertinggi ditemukan pada habitat pinggir sungaiNymphalidae is a family with the largest number of species compared to other families. This butterfly has an important role as a pollinator for pollination in an ecosystem, and can be used as an environmental bioindicator. Data on abundance and variation of Nymphalidae butterflies in the Kuwil forest area was not avilable. This study aims to analyze the abundance and species of Nymphalidae family butterflies in the Forest of the Northern Minahasa Region. The sampling technique that was used is the transect method. Transect placement in each habitat was done by Purposive Random Sampling. The habitat types at the study site are on the river banks, forests and gardens. Sampling was carried out along the transect line using sweepnet. The composition of the Nymphaldae species found was 21 species and 208 individuals. The species with have the highest abundance are Parthenos shylvia and Idea blnchardii. Diversity","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89655588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-29DOI: 10.35799/JMUO.9.2.2020.28725
Paricia Syaron Manongko, Meiske S. Sangi, L. Momuat
Telah dilakukan penelitian untuk mengetahui senyawa fitokimia dan aktivitas antioksidan ekstrak etanol tanaman patah tulang (Euphorbia tirucalli L.) menggunakan metode 1,1-difenil-2-pikrilhidrazil (DPPH). Ekstrak etanol diperoleh dengan metode maserasi kemudian diuji fitokimia untuk dilihat kandungan senyawa metabolit sekunder diantaranya alkaloid, fenolik, flavonoid, tanin, saponin, triterpenoid/steroid. Senyawa fenolik sangat berpotensi sebagai antioksidan karenanya dilakukan uji kandungan total fenolik menggunakan metode spektrofotometri dengan pereaksi Folin-Ciocalteu. Uji aktivitas antioksidan dilakukan menggunakan metode DPPH. Hasil penelitian menunjukkan bahwa ekstrak etanol mengandung senyawa metabolit sekunder yaitu fenolik ditunjukkan dengan terbentuknya warna hijau kehitaman, senyawa saponin dengan terbentuknya busa stabil, dan senyawa tanin dengan terbentuknya warna hijau kehitaman. Hasil pengujian kandungan total fenolik ekstrak etanol memiliki nilai sebesar 60,270 mg GAE/g. Kekuatan antioksidan ditentukan oleh nilai IC50 yang didasarkan pada persen perendaman radikal bebas oleh sampel uji. Untuk ekstrak etanol memiliki IC50 sebesar 82,152 µg/mL. Berdasarkan hasil yang diperoleh ekstrak etanol tanaman patah tulang memiliki potensi yang kuat sebagai antioksidan.This research was conducted to determine the phytochemical compound and antioxidant activity of ethanol extract of Patah Tulang (Euphorbia tirucalli L.) plant using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The ethanol extract was obtained by maceration and then was analysed for phytochemical compound to see the secondary metabolite contents including alkaloids, phenolics, flavonoids, tannins, saponins, triterpenoids / steroids. The phenolic compounds have high potential as antioxidant, therefore the total fenolic content was tested using spectrophotometric method with Folin-Ciocalteu reagents. Antioxidant activity was determined using DPPH method. he results showed that the ethanol extract contain secondary metabolite compounds. Penolic compounds weredetected by the formation of blackish green color, saponin compounds showed stable foam formation, and tannin compounds with a blackish green formation. Total phenolic content of the extract was60,270 mg GAE/g. Antioxidant activity was determined by IC50 value based on the percentage of free radicals taken by the sample. And ethanol extract had IC50 value of 82.152 µg /mL. Based on the results obtained, ethanol extract of Patah Tulang plants had a strong potential as an antioxidant.
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Pub Date : 2020-05-28DOI: 10.35799/JMUO.9.2.2020.28709
Christina S. H. Garakia, Meiske S. Sangi, Harry S. J. Koleangan
Penelitian ini bertujuan untuk menguji aktivitas antiinflamasi ekstrak etanol tanaman patah tulang (Euphorbia tirucalli L.) terhadap udem yang ditimbulkan oleh karagenan pada telapak kaki tikus. Ekstrak etanol tanaman patah tulang dibuat dengan teknik maserasi selama 24 jam menggunakan pelarut etanol 80%. Pengujian dilakukan dengan metode induksi karagenan menggunakan hewan uji tikus putih jantan galur wistar sebanyak 15 ekor dibagi menjadi 5 kelompok perlakuan. Kelompok pertama sebagai kontrol negatif dengan pemberian Carboxy Methyl Cellulose (CMC) 1%, kelompok kedua sebagai kontrol positif diberikan Natrium Diklofenak, kelompok ketiga diberi ekstrak etanol tanaman patah tulang dosis 5%, kelompok keempat dan kelima diberi ekstrak etanol tanaman patah tulang dengan dosis 10% dan dosis 15%. Hasil penelitian menunjukkan adanya aktivitas antiinflamasi pada pemberian ekstrak etanol tanaman patah tulang dosis 5%, dosis 10% dan dosis 15% karena setara dengan kontrol positif dan berbeda dengan kontrol negatif. Dosis yang paling baik dalam penghambatan radang adalah dosis 10% yang ditinjau dari pengukuran volume udem, persen volume dan persen inhibisi udem.This study was aimed to examine the anti-inflammatory activity of ethanol extracts of patah tulang (Euphorbia tirucalli L.) plant against edema caused by carrageenan in the soles of rat feet. Ethanol extract of patah tulang plant was obtained by maceration for 24 hours using ethanol 80%. The test was carried out by carrageenan induction method using 15 white wistar male rats divided into 5 treatment groups. The first group as a negative control was given 1% Carboxy Methyl Cellulose (CMC), the second group as a positive control was given dichlophenac sodium, and the third, fourth and fifth groups were given ethanol extracts of 5%, 10% and 15%, respectively The results showed anti-inflammatory activity in ethanol extracts of patah tulang plants at 5%, 10% and 15% because they were equivalent to positive control and different from negative control. The best dose for inflammation inhibition was the 10% dose in terms of edema voleme, percent volume and percent inhibition of edema
{"title":"Uji Aktivitas Antiinflamasi Ekstrak Etanol Tanaman Patah Tulang (Euphorbia tirucalli L.)","authors":"Christina S. H. Garakia, Meiske S. Sangi, Harry S. J. Koleangan","doi":"10.35799/JMUO.9.2.2020.28709","DOIUrl":"https://doi.org/10.35799/JMUO.9.2.2020.28709","url":null,"abstract":"Penelitian ini bertujuan untuk menguji aktivitas antiinflamasi ekstrak etanol tanaman patah tulang (Euphorbia tirucalli L.) terhadap udem yang ditimbulkan oleh karagenan pada telapak kaki tikus. Ekstrak etanol tanaman patah tulang dibuat dengan teknik maserasi selama 24 jam menggunakan pelarut etanol 80%. Pengujian dilakukan dengan metode induksi karagenan menggunakan hewan uji tikus putih jantan galur wistar sebanyak 15 ekor dibagi menjadi 5 kelompok perlakuan. Kelompok pertama sebagai kontrol negatif dengan pemberian Carboxy Methyl Cellulose (CMC) 1%, kelompok kedua sebagai kontrol positif diberikan Natrium Diklofenak, kelompok ketiga diberi ekstrak etanol tanaman patah tulang dosis 5%, kelompok keempat dan kelima diberi ekstrak etanol tanaman patah tulang dengan dosis 10% dan dosis 15%. Hasil penelitian menunjukkan adanya aktivitas antiinflamasi pada pemberian ekstrak etanol tanaman patah tulang dosis 5%, dosis 10% dan dosis 15% karena setara dengan kontrol positif dan berbeda dengan kontrol negatif. Dosis yang paling baik dalam penghambatan radang adalah dosis 10% yang ditinjau dari pengukuran volume udem, persen volume dan persen inhibisi udem.This study was aimed to examine the anti-inflammatory activity of ethanol extracts of patah tulang (Euphorbia tirucalli L.) plant against edema caused by carrageenan in the soles of rat feet. Ethanol extract of patah tulang plant was obtained by maceration for 24 hours using ethanol 80%. The test was carried out by carrageenan induction method using 15 white wistar male rats divided into 5 treatment groups. The first group as a negative control was given 1% Carboxy Methyl Cellulose (CMC), the second group as a positive control was given dichlophenac sodium, and the third, fourth and fifth groups were given ethanol extracts of 5%, 10% and 15%, respectively The results showed anti-inflammatory activity in ethanol extracts of patah tulang plants at 5%, 10% and 15% because they were equivalent to positive control and different from negative control. The best dose for inflammation inhibition was the 10% dose in terms of edema voleme, percent volume and percent inhibition of edema ","PeriodicalId":53333,"journal":{"name":"Jurnal MIPA","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73508896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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