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A comparative study between lateral internal anal sphincterotomy and botulinum toxin injection in the treatment of chronic anal fissure 外侧内肛门括约肌切开术与注射肉毒杆菌毒素治疗慢性肛裂的比较研究
Pub Date : 2021-08-09 DOI: 10.15218/zjms.2021.014
Abdulqadir Zngana, B. Hiwa
Background and objective: The gold standard for the treatment of chronic anal fissure is lateral internal sphincterotomy. Botulinum toxin injection provides temporary alleviation of sphincter spasm and allows the fissure to heal. This study aimed to compare the outcomes of lateral internal sphincterotomy and botulinum toxin injection treatments in patients with uncomplicated chronic anal fissure. Methods: A prospective comparative study was carried out at the surgical unit of Erbil teaching hospital, Erbil, Kurdistan Region of Iraq, from January 2017 to February 2018. Fifty-five patients were enrolled in this study. Five patients were excluded, and the remaining 50 patients were equally divided into two groups. Group A was managed with lateral internal sphincterotomy and group B with botulinum toxin. Postoperative pain relief, bleeding, fissure healing, incontinence, and relapse after six weeks and three months of follow-up were compared. Results: One month after treatment, 12% of the lateral internal sphincterotomy group had bleeding, while none of the botulinum toxin group (P = 0.234). Two patients (8%) of the lateral internal sphincterotomy group had pain while one (4%) of the botulinum toxin group (P >0.999).Three months after treatment, 4% of the lateral internal sphincterotomy group had bleeding, while none of the botulinum toxin group (P >0.999). None of the lateral internal sphincterotomy group had pain while one (4%) of the botulinum toxin group (P >0.999). Regarding healing, 96% of the lateral internal sphincterotomy group healed, while 92% in the botulinum toxin group (P >0.999). Conclusion: The outcome of lateral internal sphincterotomy and botulinum toxin were nearly the same, but lateral internal sphincterotomy required hospitalization, period off work, and risk of anesthesia. These risks were absent in botulinum toxin injection. Keywords: Chronic anal fissure; Lateral internal sphincterotomy; Botulinum toxin; Complications.
背景与目的:治疗慢性肛裂的金标准是外侧内括约肌切开术。注射肉毒杆菌毒素可以暂时缓解括约肌痉挛,并使裂隙愈合。本研究旨在比较内侧括约肌切开术和肉毒杆菌毒素注射治疗无并发症慢性肛裂患者的疗效。方法:2017年1月至2018年2月在伊拉克库尔德斯坦地区埃尔比勒埃尔比勒教学医院外科进行前瞻性比较研究。55名患者参与了这项研究。5名患者被排除在外,其余50名患者被平均分为两组。A组采用外侧内括约肌切开术治疗,B组采用肉毒杆菌毒素治疗。比较术后疼痛缓解、出血、裂隙愈合、失禁以及随访6周和3个月后的复发情况。结果:治疗1个月后,12%的侧内括约肌切开术组出血,而肉毒杆菌毒素组无出血(P=0.0234)。2例(8%)侧内括约肌切除术组疼痛,1例(4%)肉毒杆菌毒素治疗组疼痛(P>0.05)。治疗3个月后4%侧内括约肌切断术组出血,而肉毒杆菌毒素组均无疼痛(P>0.999)。侧内括约肌切开术组无疼痛,而肉毒杆菌毒毒素组有4%疼痛(P<0.999),在愈合方面,侧内括约肌切断术组有96%愈合,而肉毒毒素组有92%愈合(P>0999),但外侧内括约肌切开术需要住院治疗、休息一段时间以及麻醉风险。肉毒杆菌毒素注射没有这些风险。关键词:慢性肛裂;外侧内括约肌切开术;肉毒毒素;并发症。
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引用次数: 0
Molecular detection of glutamate dehydrogenase gene of Giardia lamblia isolated from food handlers in Erbil city 埃尔比勒市食品加工人员分离的蓝氏贾第鞭毛虫谷氨酸脱氢酶基因的分子检测
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.004
Hataw Saber, H. Bakr
Background and objective: Giardia lamblia is the intestinal flagellated protozoan parasite that infects vertebrates, including humans. Giardiasis is the major diarrheal disease found worldwide. It can be symptomatic or may be an asymptomatic carrier that led to chronic disease. This study aimed to determine the proportion of giardiasis among food handlers and evaluate the correlation between two laboratory methods for identifying the Giardia lamblia. Methods: A total of 308 stool samples were collected from food handlers that annually attend the central laboratory in Erbil City. Wetmount microscopic examination was performed for the diagnosis of cysts and trophozoites of the Giardia parasite. Molecular analysis done for positive samples, DNA extraction performed using the QIAamp Fast DNA Stool Mini Kit (Qiagen Company, Germany). Nested PCR analysis was done targeting the Glutamate dehydrogenase gene using two sets of primers for amplification of 734bp fragment. Gel electrophoresis was performed for visualizing the amplified DNA by Ultraviolet light. Results: The mean age of food handler participants was 29 years. Most (93.8%) of the food handlers were males, and the majority (98.6%) of the participants did not have any signs and symptoms. Four (7.4%) microscopy positive sample participants were highly educated. There was no association between educational level and positive rate by microscopy (P = 0.066). The majority of participants did not receive treatments, particularly most of the microscopic positive samples. The food handlers did not take any antiparasitic treatments 9 (3.4%) (P = 0.676). From 11 (3.6%) microscopically positive samples, 10 (90.9%) Giardia lamblia gdh gene 734 bp fragments were amplified by nested PCR. Conclusion: Amplification of 734bp of gdh gene by the nested PCR is the most specific and sensitive method for identifying Giardia lamblia. Food handlers were important people to care about sanitation and preparing food, particularly for avoiding diseases transmitted by food. Keywords: Giardiasis; Genetic characterization; gdh gene; Nested PCR.
背景与目的:兰氏贾第鞭毛虫是一种肠道鞭毛原生动物寄生虫,可感染脊椎动物,包括人类。贾第虫病是世界范围内发现的主要腹泻疾病。它可能是有症状的,也可能是导致慢性疾病的无症状携带者。本研究旨在确定食品处理人员中贾第鞭毛虫病的比例,并评价两种实验室方法鉴定贾第鞭毛虫的相关性。方法:每年到埃尔比勒市中心实验室采集食品加工人员粪便标本308份。湿山显微镜检查用于诊断贾第鞭毛虫寄生虫的囊肿和滋养体。阳性样品进行分子分析,DNA提取使用QIAamp快速DNA粪便迷你试剂盒(Qiagen公司,德国)。利用两组引物对谷氨酸脱氢酶基因进行巢式PCR分析,扩增734bp片段。用紫外灯对扩增的DNA进行凝胶电泳。结果:参与者的平均年龄为29岁。大部份(93.8%)的食物处理人员为男性,而大部份(98.6%)的参与者并无任何病征。4例(7.4%)镜检阳性受试者受过高等教育。教育程度与镜检阳性率无相关性(P = 0.066)。大多数参与者没有接受治疗,特别是大多数显微镜阳性样本。食品处理人员未采取防寄生虫措施9 (3.4%)(P = 0.676)。从11份(3.6%)镜检阳性样本中,巢式PCR扩增出10份(90.9%)兰氏贾第鞭毛虫gdh基因734 bp片段。结论:巢式PCR扩增734bp gdh基因是鉴定兰氏贾第鞭毛虫最特异、最敏感的方法。食品处理人员是关心卫生和准备食物的重要人员,特别是为了避免食物传播的疾病。关键词:贾第虫病;遗传特征;gdh基因;嵌套PCR。
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引用次数: 0
Knowledge, awareness, and preventive behaviors toward osteoporosis among a sample of premenopausal women in Erbil city, Iraq 伊拉克埃尔比勒市绝经前妇女骨质疏松症的知识、意识和预防行为
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.008
Lara Mohammed, A. Dauod
Background and objective: Osteoporosis is among the top five conditions causing disability and prolonged hospital stay; however, it is still underestimated worldwide, especially in developing countries. Therefore, this study aimed to determine the knowledge, attitude, and preventive practice in Erbil city toward this global disease. Methods: A cross-sectional study was conducted among 395 premenopausal women aged ≥25 years and ≤ 49 years old, who were recruited by simple random sampling throughout three months from the first of October to December 2015. A questionnaire was completed through a direct interview, which consisted of four parts, including questions about knowledge, attitude, practice, and demographic questions. The statistical package for the social sciences was used for data analysis. Results: The mean age of the participants was 35 ± 8.24 years. Almost half of them did not hear about osteoporosis before. The identification of risk factors by participants was poor. Out of 395 of the participants, 92.9% had no knowledge about the diagnosis of this disease. Approximately half of the participants believed that there is no way to prevent osteoporosis. Regarding practice scoring to prevent the disease, the total score (mean) was 2.9 out of a maximum of 12, which is very low, especially among females aged 25-29 years. Conclusion: The majority of premenopausal women in Erbil city had little knowledge of osteoporosis, however unaware of osteoporosis risk factors and poor preventive practice regarding prevention. Keywords: Osteoporosis; Knowledge; Premenopause; Disability; Iraq.
背景与目的:骨质疏松症是导致残疾和延长住院时间的五大疾病之一;然而,在世界范围内,特别是在发展中国家,它仍然被低估。因此,本研究旨在确定埃尔比勒市对这种全球性疾病的知识、态度和预防措施。方法:采用简单随机抽样方法,于2015年10月1日至12月3个月内,对395名年龄≥25岁,≤49岁的绝经前妇女进行横断面研究。问卷通过直接访谈的方式完成,问卷由四个部分组成,包括知识问题、态度问题、实践问题和人口问题。社会科学的统计软件包用于数据分析。结果:参与者平均年龄35±8.24岁。几乎一半的人以前没有听说过骨质疏松症。参与者对危险因素的识别能力较差。在395名参与者中,92.9%的人对这种疾病的诊断一无所知。大约一半的参与者认为没有办法预防骨质疏松症。在预防疾病的实践评分方面,总分(平均)为2.9分(满分为12分),非常低,特别是在25-29岁的女性中。结论:埃尔比勒市大部分绝经前妇女对骨质疏松知之甚少,但对骨质疏松的危险因素知之甚少,在预防方面的预防实践较差。关键词:骨质疏松症;知识;妇女;残疾;伊拉克。
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引用次数: 3
Accelerated versus conventional Ponseti protocol for the treatment of idiopathic talipes equinovarus deformity: A short term follow up in Iraq 加速与传统Ponseti方案治疗特发性马蹄足畸形:伊拉克的短期随访
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.009
J. Doski, B. Jamal
Background and objective: The accelerated protocol of Ponseti method was suggested to shorten the period of treatment of the conventional one for the cases of talipes equinovarus deformity. This study aimed to compare the accelerated protocol of Ponseti method in the treatment of clubfoot deformity with the conventional one. Methods: A prospective comparative study was conducted for infants less than six months with congenital talipes equinovarus deformity. The patients were randomized to either Group 1 (casts changed every week, conventional protocol of Ponseti method) or Group 2 (twice weekly, accelerated one). Pirani score was used to assess the severity of the deformity at presentation, at time of last cast removal, and at the last follow up visit (6th months). Results: The patients included were 48 cases with 79 feet. Group 1 (39 clubfeet) had a mean Pirani score of 5.6 (± 1.15) at presentation, which dropped to 0.47 (± 0.41) when the last cast was removed. In Group 2 (40 clubfeet), it dropped from 5.57 (± 0.83) to 0.77 (± 0.01). The result of each treatment protocol was significant, but the difference between them was not significant. Five cases (three patients aged more than three months) of Group 2 needed eight casts to reach an acceptable position of correction. The difference between the mean number of casts applied in Group 1 (5.09) and Group 2 (5.82) was statistically not significant. However, the difference between the mean number of days spent in the cast was significant. The complications occurred in 12 out of 79 feet, with no statistically significant difference between both groups. Conclusion: The accelerated protocol of Ponseti method for treating clubfoot deformity is as effective and as safe as the conventional one. It shortens the time required to complete the treatment program. Those who present lately (beyond the age of three months) may require an additional number of casts. Keywords: Clubfoot; Congenital talipes equinovarus; Ponseti; Accelerated; Cast.
背景与目的:为缩短常规马蹄内翻畸形的治疗时间,建议采用Ponseti法加速治疗方案。本研究旨在比较加速Ponseti法与常规Ponseti法治疗内翻足畸形的效果。方法:对6个月以下先天性马蹄足畸形婴儿进行前瞻性比较研究。将患者随机分为两组:1组(每周更换石膏,常规Ponseti法)和2组(每周2次,加速1次)。皮拉尼评分用于评估出现时、最后一次拆除石膏时和最后一次随访(6个月)时畸形的严重程度。结果:纳入患者48例,足部79英尺。第1组(39只内翻足)就诊时平均皮拉尼评分为5.6(±1.15)分,最后取出石膏时降至0.47(±0.41)分。第二组(40个畸形足),从5.57(±0.83)下降到0.77(±0.01)。各治疗方案的结果均有显著性,但各治疗方案之间差异不显著。2组5例(3个月以上)需要8个石膏才达到可接受的矫正位置。组1的平均铸型数为5.09,组2的平均铸型数为5.82,组间差异无统计学意义。然而,在剧组中度过的平均天数之间的差异是显著的。79只脚中有12只发生了并发症,两组之间没有统计学上的显著差异。结论:Ponseti法加速方案治疗内翻足畸形与常规方法一样安全有效。它缩短了完成治疗计划所需的时间。那些最近出现的(超过三个月)可能需要额外的数量的铸件。关键词:畸形足;先天性马蹄内翻;Ponseti;加速;演员阵容。
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引用次数: 1
The diagnosis of malignant breast lumps using fine needle aspiration cytology and ultrasonography versus histopathology 乳腺恶性肿块的细针穿刺细胞学和超声诊断与组织病理学对照研究
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.003
A. Baban
Background and objective: The most common cancer of women worldwide is breast cancer and usually presents as a breast lump. Fine needle aspiration cytology and ultrasonography are two investigational techniques used to differentiate malignant breast lump from benign one. This study aimed to find out and compare the specificity, sensitivity, and predictive values of ultrasonography versus fine needle aspiration cytology for the diagnosis of malignant breast lump. Methods: Patients who presented with clinically palpable breast lump at the department of Surgery, Rizgary Teaching Hospital, Erbil, from October 2014 to March 2016, were included. The age of the study participants ranged from 15 to 56 years. The highest rate (28.9%) was among the age group 35-45 years. Breast abscess, cystic breast lumps, and recurrent lumps have been excluded. The ultrasonographic evaluation was done by using 7.5 MHz probe for all patients at the department of radiology and fine needle aspiration cytology at the department of histopathology. All the patients underwent excision of the lumps, and histopathological examination was done for tissues. Specificity, sensitivity, and predictive values of ultrasonography and fine needle aspiration cytology were estimated, taking the histopathological result as the gold standard. A comparison of values was made. Results: Ninety patients with 93 breast lumps were included in this study. Fine needle aspiration cytology reported 28 lumps as malignant lumps and 63 as benign, and two cases were indeterminate. Ultrasonography reported 27 cases as malignant, 54 as benign, and nine as indeterminate, while three breast lumps were failed to be detected. Sensitivity, specificity, positive and negative predictive values of ultrasonography and fine needle aspiration cytology in diagnosing malignant breast lump were 94.74%, 100%, 100%, 97.22%, and 90.48%, 100%, 100%, 95.24%,respectively. Conclusion: Ultrasonography and fine needle aspiration cytology are 100% specific in diagnosing malignant breast lesions. Although ultrasonography appears more sensitive than fine needle aspiration cytology, it has a higher percentage of the indeterminate report. Keywords: Fine needle aspiration cytology; Ultrasonography; Breast lumps.
背景与目的:全世界女性最常见的癌症是癌症,通常表现为乳腺肿块。细针抽吸细胞学和超声检查是用于鉴别乳腺良恶性肿块的两种研究技术。本研究旨在找出并比较超声与细针抽吸细胞学在诊断恶性乳腺肿块中的特异性、敏感性和预测价值。方法:纳入2014年10月至2016年3月在埃尔比勒里兹加里教学医院外科出现临床可触及乳房肿块的患者。研究参与者的年龄从15岁到56岁不等。发病率最高的是35-45岁年龄组(28.9%)。乳腺脓肿、囊性乳腺肿块和复发性肿块已被排除在外。在放射科使用7.5MHz探头对所有患者进行超声评估,在组织病理学科使用细针抽吸细胞学进行超声评估。所有患者均接受了肿块切除术,并进行了组织病理学检查。以组织病理学结果为金标准,评估超声和细针穿刺细胞学的特异性、敏感性和预测值。对数值进行了比较。结果:本研究纳入了90例93个乳腺肿块的患者。细针抽吸细胞学报告28个肿块为恶性肿块,63个肿块为良性肿块,其中两个病例不确定。超声检查报告27例为恶性,54例为良性,9例为不确定,3例乳腺肿块未被发现。超声和细针穿刺细胞学诊断乳腺恶性肿块的敏感性、特异性、阳性和阴性预测值分别为94.74%、100%、100%、97.22%和90.48%、100%、10%、95.24%。尽管超声检查比细针穿刺细胞学检查更敏感,但它有更高的不确定报告百分比。关键词:细针穿刺细胞学;超声检查;乳房肿块。
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引用次数: 0
Distribution of multiple sclerosis lesions detected by brain magnetic resonance imaging in Erbil city 埃尔比勒市多发性硬化症病变的脑磁共振成像分布
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.006
Dina N. Tawfeeq, Shawnam Nasih Dawood
Background and objective: Many epidemiological studies and clinical manifestation studies of multiple sclerosis have been done in Iraq. Up to our knowledge, no such observational study to the radiological feature of the multiple sclerosis lesion has been done yet in Erbil in comparison to other worldwide studies. This study aimed to assess the distribution of multiple sclerosis lesions in brain regions detected by magnetic resonance imaging among Erbil population. Methods: This was a cross-sectional study conducted at the College of Medicine, Hawler Medical University, from April 2018 to July 2019. A review of magnetic resonance imaging scans of the brain of 120 patients was done. Special attention was directed toward identifying the variance in multiple sclerosis lesions distribution in the brain regions and their MR signal intensity characteristics. Results: Periventricular lesions were observed in more than 90% of the study sample. The next common was juxtacortical lesions (24.8%), followed by corpus callosum lesions (16.8 %), while brain stem lesions were the least observed proportions. No significant difference was detected in the distribution of multiple sclerosis lesions among ethnicities and genders, except for basal ganglia lesions, which were significantly more common in women (P = 0.016).The magnetic resonance imaging signal intensity of the lesion was significantly variable among disease duration. Conclusion: The T2 hyper intense lesions were most commonly seen in the periventricular region. Juxtacortical and corpus callosum lesions were also frequently observed. The proportions of the brain stem and cerebellum lesions appeared to be lower in comparison to previous studies. Keywords: Multiple Sclerosis; Magnetic Resonance Imaging; Distribution; Lesion.
背景和目的:在伊拉克进行了许多多发性硬化症的流行病学研究和临床表现研究。据我们所知,与世界各地的其他研究相比,埃尔比勒还没有对多发性硬化症病变的放射学特征进行这样的观察性研究。本研究旨在评估埃尔比勒人群中磁共振成像检测到的大脑区域多发性硬化症病变的分布。方法:这是一项横断面研究,于2018年4月至2019年7月在Hawler医科大学医学院进行。对120名患者的脑部磁共振成像扫描进行了回顾性研究。特别关注的是识别多发性硬化症病变在大脑区域的分布变化及其MR信号强度特征。结果:在90%以上的研究样本中观察到心室周围病变。其次是皮质旁病变(24.8%),其次是胼胝体病变(16.8%),而脑干病变的比例最低。多发性硬化症病变在种族和性别之间的分布没有显著差异,但基底节病变在女性中更常见(P=0.016)。病变的磁共振成像信号强度在疾病持续时间之间存在显著差异。结论:T2高强度病变最常见于室周区。还经常观察到枕边和胼胝体病变。与之前的研究相比,脑干和小脑病变的比例似乎更低。关键词:多发性硬化症;磁共振成像;分配损伤
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引用次数: 0
Determinants of exclusive breastfeeding practice for the first six months in mothers with infants between 6 and 15 months of age in Erbil city, Iraq: A cross-sectional study 伊拉克埃尔比勒市6至15个月婴儿的母亲头6个月纯母乳喂养的决定因素:一项横断面研究
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.001
Nabaz Sdeeq, Abubakir Saleh
Background and objective: Breastfeeding is a useful and natural source of nutrition that provides the healthiest start for an infant. Despite its nutritional benefits, breastfeeding promotes a unique and emotional connection between mother and baby. This study aimed to assess the determinants of exclusive breastfeeding within the first six months of age in Erbil City, Iraq. Methods: A cross-sectional study was conducted in Erbil city, Iraq, from December 2017 to December 2018. A convenience sampling method was used for selecting mothers of infants aged 6-15 months. A structured interviewer administered questionnaire was used for data collection. The statistical package for the social sciences was used for data analysis and a P value of ≤0.05 was regarded as statistically significant. Results: A total of 306 mothers with children aged between 6 and 15 months were included. The prevalence of exclusive breastfeeding was 26.5%. Around 36% of mothers had a primary school qualification, of whom 28.2% gave exclusive breastfeeding. Around 84%of the mother were housewives, of whom 28.3% had exclusive breastfeeding. Around 92% of the mothers had a birth at health facilities, of whom 26.2% gave exclusive breastfeeding. Around 50% of mothers had cesarean section deliveries, of whom 23.4% gave exclusive breastfeeding. Around 44% of the mothers mentioned that insufficient milk is the barrier to exclusive breastfeeding. Conclusion: Exclusive breastfeeding still remains low compared to the current WHO recommendations. The most common barrier to continuing exclusive breastfeeding was the perception of insufficient milk production. Housewife mothers are more likely to breastfeed their infants exclusively, and least when the mother is a non-house wife. Keywords: Exclusive breastfeeding; Mothers; Infants; Erbil.
背景和目的:母乳喂养是一种有益和自然的营养来源,为婴儿提供了最健康的开端。尽管母乳喂养有营养价值,但它促进了母亲和婴儿之间独特的情感联系。本研究旨在评估伊拉克埃尔比勒市婴儿出生后6个月内纯母乳喂养的决定因素。方法:于2017年12月至2018年12月在伊拉克埃尔比勒市进行横断面研究。选取6-15月龄婴儿的母亲,采用方便抽样方法。数据收集采用结构化访谈问卷。采用社会科学统计软件包进行数据分析,P值≤0.05为具有统计学意义。结果:共纳入306例6 ~ 15月龄儿童的母亲。纯母乳喂养率为26.5%。大约36%的母亲有小学学历,其中28.2%的母亲进行纯母乳喂养。约84%的母亲是家庭主妇,其中28.3%是纯母乳喂养。约92%的母亲在卫生机构分娩,其中26.2%的母亲采用纯母乳喂养。约50%的母亲采用剖宫产分娩,其中23.4%采用纯母乳喂养。约44%的母亲提到,母乳不足是纯母乳喂养的障碍。结论:与目前世卫组织的建议相比,纯母乳喂养仍然很低。继续纯母乳喂养的最常见障碍是认为产奶量不足。家庭主妇的母亲更有可能只母乳喂养婴儿,尤其是当母亲不是家庭主妇时。关键词:纯母乳喂养;母亲;婴儿;埃尔比勒。
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引用次数: 2
Role of magnetic resonance imaging in ankle sprains 磁共振成像在踝关节扭伤中的作用
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.005
NA Othman, S. AL-Najjar
Background and objective: Musculoskeletal injuries frequently occur in the ankle in both the athletic and general population. Ankle sprains are among the most frequent types of ankle injuries, which are conventionally diagnosed through clinical examinations. However, magnetic resonance imaging can provide a more precise diagnosis, leading to better injury management and prevention of consequent chronic complications. The present study aimed to examine the significance of magnetic resonance imaging in detecting and assessing changes that occur in ligaments and soft tissues in patients with ankle sprains. Methods: In a prospective study, 50 patients with ankle sprain referred to Rizgary and Erbil Teaching hospitals in Erbil city, Iraqi Kurdistan Region, from March 2018 to April 2019, were included in the study. They underwent clinical evaluation and MRI (GE general electric 1.5 Tesla). Two expert radiologists analyzed the magnetic resonance imaging images, and the results were compared. The collected data were analyzed using SPSS version 23 through descriptive statistics. Results: Most patients (64%) belonged to the age groups of 30-49 years old. Most of them (64%) were males. Most events of ankle sprain (66%) were because of sports and accidents. The clinical evaluation proved 82% of the ankle sprains. Regarding the laterality of the lesions, 60% were spotted in the right ankles and 40% in the left. According to magnetic resonance imaging results, both radiologists diagnosed that the ankle sprains included bone lesions, ligament injury, tendon injury, and effusion. There was an agreement of ≥ 96% between the two radiologists in this regard. The two radiologists were not significantly different in terms of diagnosing the ligament side. As reported by the radiologists based on the magnetic resonance imaging images, the anterior, lateral, and medial tendons were normal in most cases. Conclusion: Magnetic resonance imaging is a vitally important tool that can be utilized reliably and accurately to diagnose and evaluate changes in ligaments and soft tissues in patients with ankle sprains. Keywords: Magnetic resonance imaging (MRI); Ankle sprain; Ligaments; Injuries.
背景和目的:在运动人群和普通人群中,踝关节经常发生肌肉骨骼损伤。踝关节扭伤是最常见的踝关节损伤类型之一,通常通过临床检查进行诊断。然而,磁共振成像可以提供更精确的诊断,从而更好地处理损伤并预防随之而来的慢性并发症。本研究旨在检验磁共振成像在检测和评估踝关节扭伤患者韧带和软组织变化方面的意义。方法:在一项前瞻性研究中,将2018年3月至2019年4月在伊拉克库尔德斯坦地区埃尔比勒市Rizgary和埃尔比勒教学医院就诊的50名脚踝扭伤患者纳入研究。他们接受了临床评估和核磁共振成像(GE通用电气1.5特斯拉)。两位放射科医生分析了磁共振成像图像,并对结果进行了比较。收集的数据采用SPSS 23版进行描述性统计分析。结果:大多数患者(64%)属于30-49岁年龄组。其中大多数(64%)为男性。大多数踝关节扭伤事件(66%)是由于运动和事故引起的。临床评估证实82%的踝关节扭伤。关于病变的偏侧性,60%出现在右脚踝,40%出现在左脚踝。根据磁共振成像结果,两位放射科医生都诊断出脚踝扭伤包括骨损伤、韧带损伤、肌腱损伤和积液。两位放射科医生在这方面的一致性≥96%。两位放射科医生在诊断韧带侧方面没有显著差异。根据放射科医生根据磁共振成像图像的报告,在大多数情况下,前肌腱、外侧肌腱和内侧肌腱是正常的。结论:磁共振成像是一种非常重要的工具,可以可靠、准确地诊断和评估踝关节扭伤患者韧带和软组织的变化。关键词:磁共振成像;脚踝扭伤;韧带;受伤。
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引用次数: 0
Sickle cell disease and the adherence to guidelines for the use of blood transfusions in Duhok, Kurdistan, Iraq 伊拉克库尔德斯坦杜霍克镰状细胞病和遵守输血指南的情况
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.011
Fahad A. Jameel, Adnan Sadeeq
Background and objective: One of the important health problems in Duhok city, Iraqi Kurdistan Region, is sickle cell disease. Blood transfusion remains a significant therapeutic intervention in patients with sickle cell disease that reduces complications related to vaso-occlusions. This study aimed to assess compliance to guidelines for the use of blood transfusionsin Duhok, Kurdistan, Iraq. Methods: This is a cross-sectional study that included 135 patients with sickle cell disease registered at Jeen center of pediatric hematological diseases in Duhok, Kurdistan, Iraq. Between April 1st and July 31st, 2019, 205 medical visits of sickle cell disease were registered. Every patient was evaluated to record the clinical setting and explanations behind visiting and indications for transfusion. Results: Of 135 patients,65.9% had sickle cell anemia (HbSS disease), 33.3% had sickle beta thalassemia, and one patient (0.7%) had Sickle/D disease. A total of 205 medical visits of sickle cell disease were registered with 84 blood transfusion decisions. The most common indicated guideline reasons for transfusion were symptomatic anemia and acute hemolytic crisis with a drop of hemoglobin >2 g/dl below steady state hemoglobin and severe painful crisis only accounted for 38.1%. Conclusion: In this study of patients with sickle cell disease, most blood transfusions were not indicated according to the transfusion guidelines (British Committee for Standards in Haematology – BCSH, 2017). Keywords: Transfusion guidelines for sickle cell disease (BCSH 2017); Sickle cell disease; Iraq.
背景与目的:镰状细胞病是伊拉克库尔德斯坦地区杜霍克市的一个重要健康问题。输血仍然是镰状细胞病患者的重要治疗干预措施,可以减少与血管闭塞相关的并发症。这项研究旨在评估伊拉克库尔德斯坦杜霍克对输血使用指南的遵守情况。方法:这是一项横断面研究,包括135名在伊拉克库尔德斯坦Duhok Jeen儿科血液病中心登记的镰状细胞病患者。2019年4月1日至7月31日期间,登记了205例镰状细胞病就诊。对每位患者进行评估,以记录临床设置、访视背后的解释和输血指征。结果:135名患者中,65.9%患有镰状细胞性贫血(HbSS病),33.3%患有镰状β地中海贫血,1名患者(0.7%)患有镰状/D病。共登记了205次镰状细胞病就诊,并做出了84次输血决定。输血最常见的指示指南原因是症状性贫血和急性溶血危象,血红蛋白下降>2g/dl低于稳态血红蛋白,严重疼痛危象仅占38.1%,大多数输血没有根据输血指南进行指示(英国血液学标准委员会-BCSH,2017)。关键词:镰状细胞病输血指南(BCSH 2017);镰状细胞病;伊拉克。
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引用次数: 0
Clinicopathological study and immunohistochemical evaluation of cyclin D1 in adenomatous polyps 腺瘤性息肉细胞周期蛋白D1的临床病理研究及免疫组化评价
Pub Date : 2021-05-15 DOI: 10.15218/ZJMS.2021.007
Tenya Abdulhameed, Zheen Jaff, N. A. Maaruf
Background and objective: There are many histological types of colorectal polyps. Most of these polyps are benign epithelial polyps harboring very low risks of cancerous changes. Adenomatous polyps are the most known cancer precursors. Cyclin D1 gene amplification and or overexpression occurs in many human cancers. Cyclin D1 participates potentially in the multistep process of colorectal carcinogenesis. The present study aimed to assess the clinicopathological features of colorectal polyps and evaluate the significance of immunohistochemistry expression of cyclin D1 in adenomatouse polyp as a marker for predicting malignant transformation. Methods: A total of 180 cases of colorectal polyps were collected from Rizgary teaching Hospital and some private laboratories in Erbil, Kurdistan Region, Iraq, from January 2013 to January 2018. All cases underwent polypectomy by colonoscopy for removal of the polyp. Only cases presented with a single polyp were included. The histopathological diagnosis was revised, and the polyps were divided into four subtypes; inflammatory, hyperplastic, juvenile, and adenomas. All adenoma specimens were stained using IHC technique with cyclin D1. Results: Out of the 180 cases, the results showed that 70(38.9%) were adenomatous polyps, 56(31.1%) were hyperplastic polyps,40(22.2%) were juvenile polyps, and 14(7.8%)were inflammatory polyps. Cyclin D1 nuclear staining was detected in 24 (34.2%) adenomas. Statistical significant relations between cyclin D1 expression with male gender and with high grade dysplasia were found. Conclusion: Adenoma was the most common type among colorectal polyps. Cyclin D1 was shown to be aberrantly expressed in colorectal adenomas and may play a role in the early stages of adenoma carcinoma development. Keywords: Colorectal polyp; Cyclin D1; Adenoma.
背景与目的:结直肠息肉有多种组织学类型。这些息肉大多是良性上皮性息肉,癌变的风险很低。腺瘤性息肉是最常见的癌症前兆。细胞周期蛋白D1基因扩增和/或过度表达发生在许多人类癌症中。细胞周期蛋白D1可能参与结直肠癌发生的多步骤过程。本研究旨在评估结直肠息肉的临床病理特征,并评估细胞周期蛋白D1在腺瘤性息肉中的免疫组织化学表达作为预测恶变的标志物的意义。方法:2013年1月至2018年1月,在伊拉克库尔德斯坦地区埃尔比勒的里兹加里教学医院和一些私人实验室收集了180例结肠息肉病例。所有病例均通过结肠镜进行息肉切除术。仅包括单个息肉的病例。对组织病理学诊断进行了修订,将息肉分为四种亚型;炎症性、增生性、幼年性和腺瘤。所有腺瘤标本均用细胞周期蛋白D1进行IHC染色。结果:180例中,腺瘤性息肉70例(38.9%),增生性息肉56例(31.1%),青少年息肉40例(22.2%),炎症性息肉14例(7.8%)。24例(34.2%)腺瘤中检测到细胞周期蛋白D1核染色。细胞周期蛋白D1的表达与男性和高度发育不良之间存在统计学意义。结论:腺瘤是结直肠息肉中最常见的类型。细胞周期蛋白D1在结直肠腺瘤中异常表达,可能在腺瘤癌发展的早期阶段发挥作用。关键词:大肠息肉;细胞周期蛋白D1;腺瘤。
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引用次数: 0
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Zanco Journal of Medical Sciences
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