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Bioelectrical impedance analysis and change disability post physiotherapy for patients with lower back pain attending rehabilitation care unit in Erbil 埃尔比勒康复中心下背痛患者物理治疗后的生物电阻抗分析及残疾改变
Pub Date : 2023-08-23 DOI: 10.15218/zjms.2023.018
Reem Burkan Aldhahi, Dler Qader Omer, Sherwan Rahman Sulaiman
Background and objective: Determining the relationship between body compartments and Lower Back Pain (LBP) will increase our understanding about how body compartments can affect LBP disability. This study aimed to assess the association between body compartments and LBP disability pre and post-physiotherapy. Methods: A prospective study conducted in the main two governmental physiotherapy departments in Erbil. One Hundred patients were diagnosed with LBP and referred to physiotherapy units. All patients were assessed before starting physiotherapy and body compartments were measured by bioelectrical impedance analysis (BEIA). LBP disability was measured for each patient by a modified Oswestry disability index (ODI). After completing six sessions of physiotherapy all patients were reassessed regarding body composition, obesity measures, and LBP disability. Results: Regarding the body fat percentage (BFP), 61% of females and 56.7% of males were obese. Results showed a positive significant correlation (P = 0.013) between BFP and LBP disability after physiotherapy, while a negative significant correlation (P = 0.026) between total body water (TBW) and LBP disability. There was a significant improvement in disability after physiotherapy (P <0.001). Eleven percent of patients succeeded to reach minimal clinically important difference (MCID ≥ 30%). Body composition and other obesity measurements were not significantly different before and after physiotherapy. Conclusions: LBP disability is positively associated with BFP and negatively associated with TBW. The physiotherapy protocol performed in the physiotherapy units was able to significantly improve disability although a low number of patients reached MCID ≥ 30%. Body compartments were not significantly different before and after physiotherapy.
背景和目的:确定身体隔区与腰痛(LBP)之间的关系将增加我们对身体隔区如何影响腰痛残疾的理解。本研究旨在评估物理治疗前后体室与LBP残疾之间的关系。方法:对埃尔比勒两大政府理疗部门进行前瞻性研究。100名患者被诊断为腰痛并被转介到物理治疗单位。所有患者在开始物理治疗前进行评估,并通过生物电阻抗分析(BEIA)测量体室。通过改进的Oswestry残疾指数(ODI)测量每位患者的下bp残疾。在完成六个疗程的物理治疗后,对所有患者的身体成分、肥胖测量和腰痛残疾进行重新评估。结果:体脂率(BFP)方面,女性为61%,男性为56.7%。结果BFP与物理治疗后LBP功能障碍呈显著正相关(P = 0.013), TBW与LBP功能障碍呈显著负相关(P = 0.026)。物理治疗后残疾有显著改善(P <0.001)。11%的患者成功达到最小临床重要差异(MCID≥30%)。身体成分和其他肥胖测量在物理治疗前后没有显著差异。结论:下bp功能障碍与BFP呈正相关,与TBW呈负相关。在物理治疗单位进行的物理治疗方案能够显著改善残疾,尽管少数患者达到MCID≥30%。物理治疗前后体间室差异无统计学意义。
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引用次数: 0
Association of HLA-DRB1*04 gene with Hashimoto’s thyroiditis among Iraqi-Kurdish population in Erbil province 埃尔比勒省伊拉克库尔德人HLA-DRB1*04基因与桥本甲状腺炎的相关性研究
Pub Date : 2023-08-23 DOI: 10.15218/zjms.2023.021
Bakhtawar Ziad Omer, Sahar Mohammed Zaki Abdullah
Background and objective: Hashimoto’s thyroiditis is one of the common autoimmune thyroid diseases with increasing incidence in the general population. It has been suggested that a combination of genetic and environmental factors increase the risk of developing the disease. The current study aimed to find the association between HLA-DRB1*04 gene with Hashimoto's Thyroiditis among the Iraqi-Kurdish population in Erbil Province. Methods: The case-control study was conducted on 45 untreated patients with Hashimoto’s thyroiditis who have already been diagnosed and 45 control subjects. Blood specimens were taken from the subjects for gene detection purposes via conventional polymerase chain reaction. Sera specimens were used to run enzyme linked immunosorbent assay to measure the level of IFNγ. Results: The age of subjects ranged from 32 to 63 years with no significant difference between mean ±SE of cases (46.822±1.087 years) with the mean ±SE (47.044 ±1.162 years) of the control subjects (P = 0.999). The mean ±SE of free T3 and T4 levels was lower in cases in comparison to those of controls, while the mean ±SE of TSH level in cases was significantly higher compared to those of controls. Statistically there was a highly significant difference in the mean ±SE of free T3, free T4 and TSH levels between cases and controls (P <0.001). Furthermore, the mean ±SE of anti-TPO, anti-Tg and IFNγ levels was higher in cases compared to those of control subjects. Statistical analysis shows a highly significant difference between mean ±SE of anti-TPO and anti-Tg antibody levels of cases compared to those of controls (P <0.001). As for IFNγ level, there was a significant difference between mean±SE of IFNγ levels in cases and controls (P = 0.021). The conventional polymerase chain reaction results showed that 39/45 (86.7%) of cases were tested positive for HLA-DRB1*04, while only 20/45 (44.04 %) of the control subjects tested positive for the gene, statistical analysis revealed a highly significant association between the existence of the gene with HT disease (P <0.001). Conclusion: The study revealed a highly significant association between the existence of HLA-DRB1*04 gene and Hashimoto's thyroiditis disease among the Iraqi-Kurdish population in Erbil Province.
背景与目的:桥本甲状腺炎是一种常见的自身免疫性甲状腺疾病,在普通人群中发病率越来越高。有人认为,遗传和环境因素的结合会增加患此病的风险。本研究旨在探讨埃尔比勒省伊拉克库尔德人群中HLA-DRB1*04基因与桥本甲状腺炎的关系。方法:采用病例对照研究方法,对45例已确诊的未经治疗的桥本甲状腺炎患者和45例对照者进行研究。通过常规聚合酶链式反应从受试者身上采集血样用于基因检测。用血清标本进行酶联免疫吸附试验测定IFNγ水平。结果:受试者年龄在32~63岁之间,病例的平均±SE(46.822±1.087岁)与对照组的平均±SE47.044±1.162岁之间无显著差异(P=0.099),TSH平均±SE值明显高于对照组。病例与对照组间游离T3、游离T4和TSH水平的平均±SE差异有统计学意义(P<0.001)。此外,与对照组相比,病例的抗TPO、抗Tg和IFNγ水平的平均值±SE更高。统计分析显示,病例的抗TPO和抗Tg抗体水平的平均±SE与对照组相比有非常显著的差异(P<0.001),常规聚合酶链反应结果显示,39/45(86.7%)的病例HLA-DRB1*04阳性,而对照组中只有20/45(44.04%)的患者HLA-DRB1*44阳性,结论:在埃尔比勒省的伊拉克库尔德人中,HLA-DRB1*04基因的存在与桥本甲状腺炎有高度显著的相关性。
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引用次数: 0
Estimation of serum calcitonin, phosphate, and calcium in type 2 diabetes mellitus 2型糖尿病患者血清降钙素、磷酸盐和钙的测定
Pub Date : 2023-08-23 DOI: 10.15218/zjms.2023.023
Zahraakhan Maaroof Taher, Sardar Nouri Ahmed
Background and objective: Type two diabetes is known as insulin-independent diabetes mellitus due to body’s inability to respond to insulin and can be managed by lifestyle change and hypoglycemic tablets. This study aimed to compare serum levels of calcitonin, calcium, and phosphate between type two diabetic patients and controls. Methods: The cross-sectional study included 50 patients who have already been diagnosed with type two diabetes mellitus and 50 control subjects without clinical signs of any diseases. The level of serum calcitonin, calcium, and phosphate was estimated for all participants. Results: The mean serum level of calcitonin was (2.35 ± 1.18) pg/mL in the case group, while the mean was (32.91 ± 3.88) pg/mL in the control group (P-value = 0.001). The mean level of serum phosphate was (3.93 ± 0.08) mg/dL and (3.73 ± 0.09) mg/dL in the case and control groups, respectively (P-value = 0.117). The mean serum calcium level was (9.68 ± 0.10) mg/dL in the case group, and it was about (9.67 ± 0.14) mg/dL (P-value = 0.955) in healthy persons. Serum calcitonin was negatively correlated with glycated hemoglobin and serum glucose level. Conclusion: The calcitonin serum level in diabetic patients was significantly lower than in healthy individuals. The level of bone minerals (calcium and phosphate) was not altered in type two diabetic patients when compared with control participants.
背景和目的:2型糖尿病被称为胰岛素非依赖性糖尿病,因为身体对胰岛素没有反应,可以通过改变生活方式和降糖片来控制。本研究旨在比较2型糖尿病患者和对照组的血清降钙素、钙和磷酸盐水平。方法:横断面研究包括50名已被诊断为2型糖尿病的患者和50名没有任何疾病临床症状的对照受试者。评估所有参与者的血清降钙素、钙和磷酸盐水平。结果:病例组降钙素的平均血清水平为(2.35±1.18)pg/mL,对照组为(32.91±3.88)pg/mL.病例组和对照组的平均血清磷酸盐水平分别为(3.93±0.08)mg/dL和(3.73±0.09)mg/dL,健康人约为(9.67±0.14)mg/dL(P值=0.955)。血清降钙素与糖化血红蛋白和血糖水平呈负相关。结论:糖尿病患者血清降钙素水平明显低于健康人。与对照组相比,2型糖尿病患者的骨矿物质(钙和磷酸盐)水平没有改变。
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引用次数: 0
The prevalence of group B streptococcal infection during intrapartum period among high-risk group in labour 分娩高危人群产时B群链球菌感染的流行情况
Pub Date : 2023-08-23 DOI: 10.15218/zjms.2023.013
Bayan Nasr, S. Alalaf
Background and objective: Pregnancy associated Group B streptococcal infection is a well-established cause of significant neonatal morbidity and mortality. A cross-sectional study was conducted to determine the prevalence of Group B streptococcal infection among women presenting in labor at different ages and gestational ages and its correlation with different risk factors. Methods: Vaginal swab and urine sample for culture from 150 women having risk factors and being in labor and having risk of developing Group B streptococcal infection from 2nd of November 2020 to 2nd of December 2021. Results: The prevalence of Group B streptococcal infection among risky group women during labor in Maternity Teaching Hospital was 8%. The rate of agreement between the vaginal swab results and urine culture results was 92%. There was no significant association between urine culture results with age, parity and prolonged rupture of membrane. A significant high rate of infected urine in culture was found among women with a very extreme preterm gestational age (p value 0.049), and it was also significant among women with pyrexia (p value 0.001). Conclusion: The prevalence of Group B streptococcal infection among high-risk group of women during labor in Maternity Teaching Hospital of Erbil city was 8%.
背景和目的:妊娠相关的B组链球菌感染是新生儿发病率和死亡率高的一个公认原因。进行了一项横断面研究,以确定不同年龄和胎龄分娩妇女中B组链球菌感染的患病率及其与不同危险因素的相关性。方法:从2020年11月2日至2021年12月2日,对150名有风险因素、正在分娩并有B组链球菌感染风险的女性进行阴道拭子和尿液样本培养。结果:产科教学医院高危人群分娩期间B组链球菌感染率为8%。阴道拭子结果与尿液培养结果的一致率为92%。尿液培养结果与年龄、产次和膜破裂时间延长之间没有显著关联。结论:埃尔比勒市妇产教学医院分娩期高危人群中,B组链球菌感染率为8%。
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引用次数: 0
Early hemostatic derangements in patients with de novo acute leukemia: A single center experience 新发急性白血病患者早期止血紊乱的单中心经验
Pub Date : 2023-08-23 DOI: 10.15218/zjms.2023.019
Sarah Laith Alnuaimy, Rawand P. Shamoon
Background and objective: Bleeding and thrombosis are major causes of morbidity and mortality in patients with acute leukemia (AL); they are attributed to hemostatic derangement and coagulation defects that are associated with leukemia. There is a paucity of information regarding coagulopathy in AL patients in our locality; this study, therefore, was employed to evaluate hemostatic parameters in patients with AL at the time of presentation. Methods: This prospective cross-sectional study included 84 newly diagnosed patients with AL. The study was carried out at Nanakali hemato-oncology center from September 2021 to May 2022. Patients were assessed for coagulation parameters including prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen level (FBG), D-dimer (D-Di), antithrombin (AT), protein C (PC), and protein S (PS). Results: The median age of the studied patients was 26 years with a male to female ratio of 1.1:1. Acute myeloid leukemia (AML) patients constitutes 51.2% (43 patients), and the remaining 41 (48.8%) patients had acute lymphoblastic leukemia (ALL). PT was significantly prolonged, D-Di was significantly higher and AT, and PC were significantly decreased in AML compared to control groups. Only D-Di level was significantly higher in ALL compared to control groups. Bleeding manifestations were encountered in 40 (47.6%) patients with a higher incidence among the AML group (28 patients, 70%). Thrombosis occurred in 2 (2.4%) patients. Conclusion: Defects of coagulation were common in AL. Hemostatic derangement and bleeding at the time of presentation were more noticeable in patients with AML.
背景与目的:出血和血栓形成是急性白血病(AL)患者发病和死亡的主要原因;它们被归因于与白血病相关的止血紊乱和凝血缺陷。在我们地区,关于AL患者凝血障碍的信息很少;因此,本研究用于评估AL患者在出现时的止血参数。方法:这项前瞻性横断面研究包括84名新诊断的AL患者。该研究于2021年9月至2022年5月在纳那卡利血液肿瘤中心进行。评估患者的凝血参数,包括凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原水平(FBG)、D-二聚体(D-Di)、抗凝血酶(AT)、蛋白C(PC)和蛋白S(PS)。结果:研究患者的中位年龄为26岁,男女比例为1.1:1。急性髓细胞白血病(AML)患者占51.2%(43例),其余41例(48.8%)患者患有急性淋巴细胞白血病(ALL)。与对照组相比,AML的PT显著延长,D-Di显著升高,AT和PC显著降低。ALL中只有D-Di水平显著高于对照组。40例(47.6%)患者出现出血表现,AML组中出血发生率较高(28例,70%)。血栓形成发生在2例(2.4%)患者中。结论:AL患者常见凝血功能缺损,AML患者表现时止血紊乱和出血更为明显。
{"title":"Early hemostatic derangements in patients with de novo acute leukemia: A single center experience","authors":"Sarah Laith Alnuaimy, Rawand P. Shamoon","doi":"10.15218/zjms.2023.019","DOIUrl":"https://doi.org/10.15218/zjms.2023.019","url":null,"abstract":"Background and objective: Bleeding and thrombosis are major causes of morbidity and mortality in patients with acute leukemia (AL); they are attributed to hemostatic derangement and coagulation defects that are associated with leukemia. There is a paucity of information regarding coagulopathy in AL patients in our locality; this study, therefore, was employed to evaluate hemostatic parameters in patients with AL at the time of presentation. Methods: This prospective cross-sectional study included 84 newly diagnosed patients with AL. The study was carried out at Nanakali hemato-oncology center from September 2021 to May 2022. Patients were assessed for coagulation parameters including prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen level (FBG), D-dimer (D-Di), antithrombin (AT), protein C (PC), and protein S (PS). Results: The median age of the studied patients was 26 years with a male to female ratio of 1.1:1. Acute myeloid leukemia (AML) patients constitutes 51.2% (43 patients), and the remaining 41 (48.8%) patients had acute lymphoblastic leukemia (ALL). PT was significantly prolonged, D-Di was significantly higher and AT, and PC were significantly decreased in AML compared to control groups. Only D-Di level was significantly higher in ALL compared to control groups. Bleeding manifestations were encountered in 40 (47.6%) patients with a higher incidence among the AML group (28 patients, 70%). Thrombosis occurred in 2 (2.4%) patients. Conclusion: Defects of coagulation were common in AL. Hemostatic derangement and bleeding at the time of presentation were more noticeable in patients with AML.","PeriodicalId":53383,"journal":{"name":"Zanco Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49614558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The correlation between Blood group type and Diabetes Mellitus Type II 血型与II型糖尿病的相关性研究
Pub Date : 2023-04-26 DOI: 10.15218/zjms.2023.003
S. Mizouri
Background and objective: Type 2 diabetes mellitus is typically a multifactorial disorder involving genetic and environmental factors to variable extents. The aim of this research was to find out if there is a relationship between the “ABO” and “Rhesus” blood groups and type 2 diabetes mellitus. Methods: A case-control study was carried out at Azadi Teaching Hospital in Duhok city for six months, from 1st July 2019 to 1st January 2020. The study included 800 individuals including 400 randomly selected diabetic patients and 400 non-diabetic adults of both genders. Standard slide agglutination method at room temperature was performed to determine the ABO and Rh blood groups. Results: Out of 400 patients, 185(46.25%) were male and 215(53.75%) were female. It was found that out of 400 randomly selected patients, majority had O blood group 193(48.25%), 109(27.25%) had A, 65(16.25%) had B, 33(8.25%) had AB group. A higher frequency of O blood group was encountered among the diabetics comparing to the control (48.25% vs. 37.75%). On applying the Chi-square test, the blood groups O and type 2 diabetes mellitus were found to have a statistically significant relationship (Chi-square value - 8.14, P <0.005) and no statistically significant association between the Rh group and type 2 DM was observed (P >0.05). Conclusion: According to this study, people with the O blood group are at a greater risk of having type 2 diabetes mellitus, but there was no discrepancy in type 2 diabetes mellitus risk between Rhesus positive and negative classes. The level of blood groups A among diabetic patients is also concluded to be substantially lower.
背景与目的:2型糖尿病是一种典型的多因素疾病,遗传和环境因素在不同程度上涉及。这项研究的目的是找出ABO血型和恒河猴血型与2型糖尿病之间是否存在关系。方法:2019年7月1日至2020年1月1日,在杜霍克市阿扎迪教学医院进行为期6个月的病例对照研究。该研究包括800人,其中包括400名随机选择的糖尿病患者和400名非糖尿病成年人,男女皆有。采用室温标准玻片凝集法测定ABO和Rh血型。结果:400例患者中,男性185例(46.25%),女性215例(53.75%)。随机抽取400例患者,以O型为主193例(48.25%),A型109例(27.25%),B型65例(16.25%),AB型33例(8.25%)。糖尿病患者中O型血的发生率高于对照组(48.25% vs. 37.75%)。经卡方检验,O型血与2型糖尿病有统计学意义(χ 2值为- 8.14,P < 0.05)。结论:根据本研究,O型血的人患2型糖尿病的风险更大,但恒河血型阳性和阴性的人患2型糖尿病的风险没有差异。糖尿病患者的A型血水平也明显较低。
{"title":"The correlation between Blood group type and Diabetes Mellitus Type II","authors":"S. Mizouri","doi":"10.15218/zjms.2023.003","DOIUrl":"https://doi.org/10.15218/zjms.2023.003","url":null,"abstract":"Background and objective: Type 2 diabetes mellitus is typically a multifactorial disorder involving genetic and environmental factors to variable extents. The aim of this research was to find out if there is a relationship between the “ABO” and “Rhesus” blood groups and type 2 diabetes mellitus. Methods: A case-control study was carried out at Azadi Teaching Hospital in Duhok city for six months, from 1st July 2019 to 1st January 2020. The study included 800 individuals including 400 randomly selected diabetic patients and 400 non-diabetic adults of both genders. Standard slide agglutination method at room temperature was performed to determine the ABO and Rh blood groups. Results: Out of 400 patients, 185(46.25%) were male and 215(53.75%) were female. It was found that out of 400 randomly selected patients, majority had O blood group 193(48.25%), 109(27.25%) had A, 65(16.25%) had B, 33(8.25%) had AB group. A higher frequency of O blood group was encountered among the diabetics comparing to the control (48.25% vs. 37.75%). On applying the Chi-square test, the blood groups O and type 2 diabetes mellitus were found to have a statistically significant relationship (Chi-square value - 8.14, P <0.005) and no statistically significant association between the Rh group and type 2 DM was observed (P >0.05). Conclusion: According to this study, people with the O blood group are at a greater risk of having type 2 diabetes mellitus, but there was no discrepancy in type 2 diabetes mellitus risk between Rhesus positive and negative classes. The level of blood groups A among diabetic patients is also concluded to be substantially lower.","PeriodicalId":53383,"journal":{"name":"Zanco Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42661511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Women's expectations of health care providers in the labor and delivery room in the Kurdistan Region of Iraq 伊拉克库尔德斯坦地区妇女对分娩室医护人员的期望
Pub Date : 2023-04-26 DOI: 10.15218/zjms.2023.007
Aveen Hajimam, H. Ahmed, Kathryn E Mishkin
Background and objective: The World Health Organization recognizes the importance of positive childbirth experience. In Iraq, patient satisfaction during maternity care visits is not routinely collected. This study was aimed to find out the women’s expectation during labor from physicians and midwives and associated factors such as socio-demographic and obstetrical characteristics. Methods: This cross-sectional study was conducted in Erbil city, located in the Kurdistan region of Iraq. A total of 1,500 women were targeted while they were accompanying another person, including children, to receive health services in Erbil and eventually 1,196 participated in the study. Data were collected through direct interviews after receiving informed oral consent. Participants were asked to describe their expectations for childbirth using an open-ended question. Responses were then grouped and categorized into 20 expectation items based on overlapping themes. Chi-square tests were used to identify associations with key socio-demographic and obstetric characteristics. Results: Level of expectation was significantly associated with education (illiterate and high education, P = 0.028),residency (suburban, P = 0.003), parity (grand multipara, P = 0.001), satisfaction with care (those satisfied, P <0.001), and satisfaction with provider communication (those satisfied, P <0.001). This study found that positive and calming verbal and non-verbal expressions, environmental control, encouragement of different positions and mobilization, hygiene, promotion of urinary elimination, and instruction on breathing and relaxation are highly expected by parturient women. Conclusion: Understanding women’s expectations in the delivery room is critical to health care providers in order to make appropriate care plan and support women to have a positive birth experience and to meet expectations.
背景和目标:世界卫生组织认识到积极分娩经验的重要性。在伊拉克,没有定期收集产妇护理就诊期间患者的满意度。本研究旨在了解医生和助产士对女性分娩的期望以及社会人口统计学和产科特征等相关因素。方法:这项横断面研究在伊拉克库尔德斯坦地区的埃尔比勒市进行。共有1500名妇女在埃尔比勒陪同包括儿童在内的另一个人接受医疗服务时成为目标,最终有1196人参与了这项研究。在获得知情口头同意后,通过直接访谈收集数据。参与者被要求用一个开放式问题描述他们对分娩的期望。然后根据重叠的主题将答复分组并分类为20个期望项目。卡方检验用于确定与关键社会人口统计学和产科特征的相关性。结果:期望水平与教育程度(文盲和高等教育,P=0.028)、居住(郊区,P=0.003)、产程(大经产妇,P=0.001)、对护理的满意度(满意者,P<0.001)和对提供者沟通的满意度(满意度,P<0.001,环境控制、鼓励不同的体位和动员、卫生、促进排尿以及呼吸和放松的指导是产妇的高度期望。结论:了解妇女在产房的期望对于卫生保健提供者制定适当的护理计划和支持妇女获得积极的分娩体验并满足期望至关重要。
{"title":"Women's expectations of health care providers in the labor and delivery room in the Kurdistan Region of Iraq","authors":"Aveen Hajimam, H. Ahmed, Kathryn E Mishkin","doi":"10.15218/zjms.2023.007","DOIUrl":"https://doi.org/10.15218/zjms.2023.007","url":null,"abstract":"Background and objective: The World Health Organization recognizes the importance of positive childbirth experience. In Iraq, patient satisfaction during maternity care visits is not routinely collected. This study was aimed to find out the women’s expectation during labor from physicians and midwives and associated factors such as socio-demographic and obstetrical characteristics. Methods: This cross-sectional study was conducted in Erbil city, located in the Kurdistan region of Iraq. A total of 1,500 women were targeted while they were accompanying another person, including children, to receive health services in Erbil and eventually 1,196 participated in the study. Data were collected through direct interviews after receiving informed oral consent. Participants were asked to describe their expectations for childbirth using an open-ended question. Responses were then grouped and categorized into 20 expectation items based on overlapping themes. Chi-square tests were used to identify associations with key socio-demographic and obstetric characteristics. Results: Level of expectation was significantly associated with education (illiterate and high education, P = 0.028),residency (suburban, P = 0.003), parity (grand multipara, P = 0.001), satisfaction with care (those satisfied, P <0.001), and satisfaction with provider communication (those satisfied, P <0.001). This study found that positive and calming verbal and non-verbal expressions, environmental control, encouragement of different positions and mobilization, hygiene, promotion of urinary elimination, and instruction on breathing and relaxation are highly expected by parturient women. Conclusion: Understanding women’s expectations in the delivery room is critical to health care providers in order to make appropriate care plan and support women to have a positive birth experience and to meet expectations.","PeriodicalId":53383,"journal":{"name":"Zanco Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49113109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunohistochemical expression of PTEN (phosphatase and tension homolog) in endometrial carcinoma PTEN(磷酸酶和张力同源物)在子宫内膜癌中的免疫组织化学表达
Pub Date : 2023-04-26 DOI: 10.15218/zjms.2023.012
Zenaib Ali, Payman Berzinji
Background and objective: Different molecular alterations have been described in the pathogenesis of endometrial carcinoma, among themis mutation of the PTEN (phosphatase and tension homolog), a tumor suppressor gene. This study aimed to detect PTEN immunoexpression in endometrial carcinoma and to asses the association between PTEN immunoexpression with the clinicopathological parameters. Methods: This cross-sectional retrospective study was carried out between January 2016-December 2021 in Erbil city. A total of 112 formalin fixed, paraffin embedded, archival tissue blocks of total abdominal hysterectomy samples were collected in Erbilcity. The clinicopathological characteristics of the tumors were revised, and the specimens were analyzed immunohistochemically using monoclonal PTEN antibody clone 6H2.1 (Dako. Results: Seventy- seven cases (68.8%) were labeled as negative for PTEN immunoexpression. While 35 cases (31.2%) were labeled as positive for PTEN immunoexpression. PTEN immunoexpression was significantly associated with the tumor histological types (P = 0.001), while no significant association was found between PTEN immunoexpression and other clinicopathological parameters. Conclusion: Loss of PTEN immunoexpression frequently seen in endometrioid type of endometrial carcinoma than other types of endometrial carcinoma and is significantly associated with the histological types of endometrial carcinoma.
背景和目的:子宫内膜癌的发病机制中有不同的分子改变,其中包括抑癌基因PTEN(磷酸酶和张力同源物)的突变。本研究旨在检测PTEN在子宫内膜癌中的免疫表达,并评估PTEN免疫表达与临床病理参数之间的关系。方法:这项横断面回顾性研究于2016年1月至2021年12月在埃尔比勒市进行。在埃尔比勒市共收集了112个福尔马林固定、石蜡包埋的全腹子宫切除术档案组织块样本。对肿瘤的临床病理特征进行了修正,并用单克隆PTEN抗体克隆6H2.1(Dako)对标本进行了免疫组化分析。结果:77例(68.8%)PTEN免疫表达阴性。PTEN免疫表达阳性35例(31.2%)。PTEN的免疫表达与肿瘤组织学类型显著相关(P=0.001),而PTEN免疫表达与其他临床病理参数之间没有显著相关性。结论:PTEN免疫表达缺失在子宫内膜样型子宫内膜癌中较其他类型的子宫内膜癌常见,并与子宫内膜癌的组织学类型显著相关。
{"title":"Immunohistochemical expression of PTEN (phosphatase and tension homolog) in endometrial carcinoma","authors":"Zenaib Ali, Payman Berzinji","doi":"10.15218/zjms.2023.012","DOIUrl":"https://doi.org/10.15218/zjms.2023.012","url":null,"abstract":"Background and objective: Different molecular alterations have been described in the pathogenesis of endometrial carcinoma, among themis mutation of the PTEN (phosphatase and tension homolog), a tumor suppressor gene. This study aimed to detect PTEN immunoexpression in endometrial carcinoma and to asses the association between PTEN immunoexpression with the clinicopathological parameters. Methods: This cross-sectional retrospective study was carried out between January 2016-December 2021 in Erbil city. A total of 112 formalin fixed, paraffin embedded, archival tissue blocks of total abdominal hysterectomy samples were collected in Erbilcity. The clinicopathological characteristics of the tumors were revised, and the specimens were analyzed immunohistochemically using monoclonal PTEN antibody clone 6H2.1 (Dako. Results: Seventy- seven cases (68.8%) were labeled as negative for PTEN immunoexpression. While 35 cases (31.2%) were labeled as positive for PTEN immunoexpression. PTEN immunoexpression was significantly associated with the tumor histological types (P = 0.001), while no significant association was found between PTEN immunoexpression and other clinicopathological parameters. Conclusion: Loss of PTEN immunoexpression frequently seen in endometrioid type of endometrial carcinoma than other types of endometrial carcinoma and is significantly associated with the histological types of endometrial carcinoma.","PeriodicalId":53383,"journal":{"name":"Zanco Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46459022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A prospective evaluation of computerized tomography scan findings in blunt abdominal trauma 钝性腹部创伤的计算机断层扫描结果的前瞻性评价
Pub Date : 2023-04-26 DOI: 10.15218/zjms.2023.009
A. Jamal, Balen Muhammad, Medya Sadeq
Background and objective: Evaluating patients with blunt abdominal trauma remains one of the most challenging aspects of acute trauma care. CT scan of abdomen remains the standard imaging modality for evaluation of abdominal trauma cases. The aim of this study is to evaluate CT scan findings in blunt abdominal trauma victims with respect to solid organ injuries, hollow viscus injuries, associated thoracic and abdominal wall injuries, associated hemoperitoneum, cause of injury and type of management. Methods: A cross-sectional study was conducted among 96 hemodynamically stable patients with history of blunt abdominal trauma who underwent CT scan examination in Rozh-halat Emergency Hospital from June 2021-January 2022; using a 64 multi-detector helical slice CT scanner. Data analysis were performed on patient’s demographics, mode and type of injury, CT scan findings and severity scorings, associated injuries and type of management. Results: The mean age of enrolled cases was 28.6 ± 18.6 ranged from 4-70 years. About two third (63.5%) were males and one third were females (36.5%). The most common cause of trauma was road traffic accident (64% of cases). Out of 96 trauma cases; 87.5% of patients had positive CT findings of which 50% had hemoperitoneum, 21.9% had pneumoperitoneum, 66.7% had no hallow viscous involvement, while 33.2% had hollow viscus involvement. One third of cases had associated abdominal wall injury. 56.4% of patients had multiple organ injury. Regarding solid organ injury; 66.7% of cases had spleen injury, (36.5%) had liver injury, Pancreas was involved in 12.5% of cases. RT& LT – kidneys showed grade 2 injury in (9.4%) & (6.3 %) respectively. Half of patients with positive CT scan findings had no lower chest injury findings. This study showed that 43.8% of cases were managed conservatively, 45.9% underwent laparotomy, the incidental finding of intra-operative hemoperitoneum which was negative in CT scan was only 1%. Conclusion: CT imaging is the diagnostic tool of choice for the evaluation of blunt abdominal trauma in haemo-dynamically stable patients as it can assist in detecting and evaluating other co-existing injuries such as lower thoracic, pelvic and spine injuries apart from its main role in accurate identification of intra -abdominal injuries and associated bleeding.
背景和目的:评估钝性腹部创伤患者仍然是急性创伤护理中最具挑战性的方面之一。腹部CT扫描仍然是评估腹部创伤病例的标准成像方式。本研究的目的是评估钝性腹部创伤患者的CT扫描结果,包括实体器官损伤、内脏中空损伤、胸腹壁相关损伤、腹腔积血、损伤原因和治疗类型。方法:对2021年6月至2022年1月在罗日哈拉特急救医院接受CT扫描检查的96名有钝性腹部创伤史的血液动力学稳定患者进行横断面研究;使用64个多探测器的螺旋切片CT扫描仪。对患者的人口统计学、损伤模式和类型、CT扫描结果和严重程度评分、相关损伤和治疗类型进行数据分析。结果:入选病例的平均年龄为28.6±18.6,年龄范围为4-70岁。约三分之二(63.5%)为男性,三分之一为女性(36.5%)。最常见的创伤原因是道路交通事故(64%)。96例创伤病例中;87.5%的患者CT表现为阳性,其中腹腔积血占50%,气腹占21.9%,无hallow粘稠病变占66.7%,内脏中空病变占33.2%。三分之一的病例有相关的腹壁损伤。56.4%的患者有多器官损伤。关于实体器官损伤;脾损伤占66.7%,肝损伤占36.5%,胰腺损伤占12.5%。RT和LT–肾脏显示2级损伤,分别为(9.4%)和(6.3%)。CT扫描呈阳性的患者中,有一半没有下胸部损伤。本研究显示,43.8%的病例是保守治疗的,45.9%的病例是剖腹手术,CT扫描阴性的术中腹腔积血的偶然发现率仅为1%。结论:CT成像是评估血流动力学稳定患者腹部钝性损伤的首选诊断工具,因为它除了在准确识别腹部损伤和相关出血方面发挥主要作用外,还可以帮助检测和评估其他共同存在的损伤,如下胸、骨盆和脊椎损伤。
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引用次数: 0
Detection of carbapenemase in acinetobacter baumannii enrolled in the relationship between biofilm formation and antibiotic resistance 鲍曼不动杆菌碳青霉烯酶的检测研究了生物膜形成与抗生素耐药性的关系
Pub Date : 2023-04-26 DOI: 10.15218/zjms.2023.010
Sayran A. Qader, Aryan R. Ganjo
Background and objective: Acinetobacter baumannii is a significant pathogenic bacterium in the health system. The ability to resist antimicrobial drugs and biofilm formation gives the considerable capacity to A. baumannii for existing in a harsh environment, enabling this bacterium to cause hospital-acquired infection. Carbapenem is an important treatment option for severe nosocomial infection and patients infected by multidrug-resistant organisms. The main aim of this study is to detect carbapenemase in isolates, and its association with biofilm formation as well as antibiotic resistance. Methods: Sixty A. baumannii isolates were obtained from several hospital districts in Erbil city. Identification and antimicrobial susceptibility test (AST) of isolates were performed by VITEKII compact system. Phenotypic identification of carbapenem by sCIM also biofilm-forming was detected by 96 well method. Additionally, three antimicrobial agents were used if they were successful in eliminating biofilm formation. . Results: The majority of the isolates were from sputum, accounting 75% and antibiotic susceptibility showed that the isolates are resistant to the most available antibiotics, and significant of the isolates formed strong biofilm. The sensitivity of meropenem, ceftazidime, and ciprofloxacin were employed for ten isolates of A. baumannii after biofilm formation it was found that biofilm cells need more concentration of antibiotic than planktonic cells then phenotypic detection of carbapenem showed that the overall positive values were 30 (50.0%) for sCIM. Conclusion: We revealed that most resistant isolates have a greater capacity for biofilm development than sensitivite isolates. Biofilm-producing strains of A. baumannii cannot be killed with the relatively similar concentration of antimicrobial drugs that are needed to kill planktonic cells.
背景与目的:鲍曼不动杆菌是卫生系统中一种重要的致病菌。抗微生物药物和生物膜形成的能力使鲍曼不动杆菌在恶劣环境中具有相当大的生存能力,使这种细菌能够引起医院获得性感染。碳青霉烯是严重医院感染和耐多药生物感染患者的重要治疗选择。本研究的主要目的是检测分离株中的碳青霉烯酶,及其与生物膜形成和抗生素耐药性的关系。方法:从埃尔比勒市多个医院区获得60株鲍曼不动杆菌分离株。采用VITEKII紧凑型系统对分离株进行鉴定和药敏试验。sCIM法鉴定碳青霉烯类化合物的表型,96孔法检测生物膜的形成。此外,如果三种抗菌剂成功消除了生物膜的形成,则使用它们。结果:大多数分离株来自痰液,占75%。抗生素敏感性表明,这些分离株对最有效的抗生素具有耐药性,并且显著的分离株形成了强大的生物膜。采用美罗培南、头孢他啶和环丙沙星对10株鲍曼不动杆菌生物膜形成后的敏感度进行检测,发现生物膜细胞比浮游细胞需要更高浓度的抗生素,碳青霉烯的表型检测显示,sCIM的总阳性值为30(50.0%)。结论:我们发现大多数耐药菌株比敏感菌株具有更大的生物膜形成能力。鲍曼不动杆菌的生物膜产生菌株不能用杀死浮游细胞所需的相对相似浓度的抗菌药物杀死。
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引用次数: 0
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Zanco Journal of Medical Sciences
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