Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18057
Robert Mustafin, Kamalutdin Nizamutdinovich Gadzhiev, Yuri Kuchin, Samvel Antonyan, Ivan Anatolyevich Malafeev, Rail Khazisovich Ilyasov, Yulia Molchanova
{"title":"The gastric resection with reconstruction surgery for complications of peptic ulcer disease in emergency surgery","authors":"Robert Mustafin, Kamalutdin Nizamutdinovich Gadzhiev, Yuri Kuchin, Samvel Antonyan, Ivan Anatolyevich Malafeev, Rail Khazisovich Ilyasov, Yulia Molchanova","doi":"10.14300/mnnc.2023.18057","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18057","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135909453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18052
Pavel Koroy, Temirlan Ruslanovich Dudov, Alexandr Yagoda, Vijaya Sarithala
Chronic liver diseases are characterized by the activation of stellate cells and increased extracellular matrix (ECM) accumulation, which leads to the evolution and advancement of liver fibrosis. Hepatic fibrogenesis is based on an imbalance be-tween the collection and degradation of ECM, caused, among other things, by impaired matrix metalloproteinases (MMPs) expression. The review presents data on the biological role of various MMPs in normal and liver diseases. Clarifying the place of MMP in noninvasive and early diagnosis of chronic liver diseases will optimize the management of this category of patients.
{"title":"Matrix metalloproteinases: the role in evolution of liver diseases","authors":"Pavel Koroy, Temirlan Ruslanovich Dudov, Alexandr Yagoda, Vijaya Sarithala","doi":"10.14300/mnnc.2023.18052","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18052","url":null,"abstract":"Chronic liver diseases are characterized by the activation of stellate cells and increased extracellular matrix (ECM) accumulation, which leads to the evolution and advancement of liver fibrosis. Hepatic fibrogenesis is based on an imbalance be-tween the collection and degradation of ECM, caused, among other things, by impaired matrix metalloproteinases (MMPs) expression. The review presents data on the biological role of various MMPs in normal and liver diseases. Clarifying the place of MMP in noninvasive and early diagnosis of chronic liver diseases will optimize the management of this category of patients.","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135987613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18004
V. L. Korobka, Viktor Dmitrievich Pasechnikov, Ekaterina S. Pak, A. M. Shapovalov, D. Pasechnikov, I. Shitikov
{"title":"Comparison of the effectiveness of non-selective β-blockers and endoscopic band ligation of esophageal varices in the primary prevention of bleeding in ascites patients from the waiting list for liver transplantation","authors":"V. L. Korobka, Viktor Dmitrievich Pasechnikov, Ekaterina S. Pak, A. M. Shapovalov, D. Pasechnikov, I. Shitikov","doi":"10.14300/mnnc.2023.18004","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18004","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66994926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18014
A. Grigoryan, A. Bezhin, T. Pankrusheva, Lyudmila V. Zhilyaeva, S. Efanov, Larisa Vasilyevna Atrepyeva
{"title":"рН-sensitive dressing material in monitoring the wound process","authors":"A. Grigoryan, A. Bezhin, T. Pankrusheva, Lyudmila V. Zhilyaeva, S. Efanov, Larisa Vasilyevna Atrepyeva","doi":"10.14300/mnnc.2023.18014","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18014","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66995853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18045
I. Gerasimenko, A. Obedin, S. Timofeev, A.G. Isaeva, A. Grigorova, Dmitry Nikolaevich Mashchenko, Oksana Igorevna Iachnaia, Anastasia Alekseevna Lytkina
(2.3+1.1 and 6.8+1.2 days, p<0.05) and the timing of the start of enteral nutrition (3.7+1.5 and 6.7+2.2 days, p<0.05). With unrestricted access of mothers of newborns with NEC to ICU, the microbial spectrum in cultures from different loci was significantly richer. However, further research is needed to explore this approach in preterm infants with NEC.
{"title":"Evaluation of short-term outcomes in preterm infants with necrotizing enterocolitis","authors":"I. Gerasimenko, A. Obedin, S. Timofeev, A.G. Isaeva, A. Grigorova, Dmitry Nikolaevich Mashchenko, Oksana Igorevna Iachnaia, Anastasia Alekseevna Lytkina","doi":"10.14300/mnnc.2023.18045","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18045","url":null,"abstract":"(2.3+1.1 and 6.8+1.2 days, p<0.05) and the timing of the start of enteral nutrition (3.7+1.5 and 6.7+2.2 days, p<0.05). With unrestricted access of mothers of newborns with NEC to ICU, the microbial spectrum in cultures from different loci was significantly richer. However, further research is needed to explore this approach in preterm infants with NEC.","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66995884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18020
A. Yagoda, N. Gladkikh, P. Koroy, Viktorovna Borodina Lyudmila
{"title":"A clinical case of microscopic polyarteritis complicated by aseptic thrombendocarditis with aortic valve lesion","authors":"A. Yagoda, N. Gladkikh, P. Koroy, Viktorovna Borodina Lyudmila","doi":"10.14300/mnnc.2023.18020","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18020","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66995918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18038
V. Malyshko, A. Basov, A. Dorohova, A. Moiseev, Oleg Vyacheslavovich Dyakov, I. Pavlyuchenko, Aleksandr Storozhuk
The study determined the effect of silver nanoparticles (AgNPs) in the treatment of purulent wounds with negative pressure instillations (NPWTi) on the parameters of the antioxidant system of blood and exudate. The study was conducted on 72 laboratory animals, which were divided into four equal groups. In contrast, in 3 groups, it was performed by modeling a purulent wound with its further treatment in various ways. In group 1, the traditional treatment method was used under a bandage with a levomekol; in group 2, wound treatment was carried out using a preparation with AgNPs; in group 3, the NPWTi method was used. In group 4 (control), modeling of a purulent wound was not performed. During the experiment, a study was made of the parameters of the enzyme link of antioxidant protection (catalase and superoxide dismutase), as well as the total antioxidant activity due to the content of low molecular weight substrates. It should be noted that only in animals of group 3, the indicator of antioxidant activity of the blood reached the values of the control group on the 12th day. In contrast, in group 2 it remained significantly reduced by 13.2 %. The data obtained indicate the ability of AgNPs to increase the prooxidant load in the wound area mainly in the first six days, with the development of an imbalance in the work of enzymes of the 1st and 2nd lines of antioxidant protection. This may indicate the advisability of the combined use of AgNPs and NPWTi in treating the first phase of the wound process.
{"title":"Dynamics of indicators of the prooxidant-antioxidant system in the blood and exudate under the treatment of purulent wounds with negative pressure and silver nanoparticles","authors":"V. Malyshko, A. Basov, A. Dorohova, A. Moiseev, Oleg Vyacheslavovich Dyakov, I. Pavlyuchenko, Aleksandr Storozhuk","doi":"10.14300/mnnc.2023.18038","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18038","url":null,"abstract":"The study determined the effect of silver nanoparticles (AgNPs) in the treatment of purulent wounds with negative pressure instillations (NPWTi) on the parameters of the antioxidant system of blood and exudate. The study was conducted on 72 laboratory animals, which were divided into four equal groups. In contrast, in 3 groups, it was performed by modeling a purulent wound with its further treatment in various ways. In group 1, the traditional treatment method was used under a bandage with a levomekol; in group 2, wound treatment was carried out using a preparation with AgNPs; in group 3, the NPWTi method was used. In group 4 (control), modeling of a purulent wound was not performed. During the experiment, a study was made of the parameters of the enzyme link of antioxidant protection (catalase and superoxide dismutase), as well as the total antioxidant activity due to the content of low molecular weight substrates. It should be noted that only in animals of group 3, the indicator of antioxidant activity of the blood reached the values of the control group on the 12th day. In contrast, in group 2 it remained significantly reduced by 13.2 %. The data obtained indicate the ability of AgNPs to increase the prooxidant load in the wound area mainly in the first six days, with the development of an imbalance in the work of enzymes of the 1st and 2nd lines of antioxidant protection. This may indicate the advisability of the combined use of AgNPs and NPWTi in treating the first phase of the wound process.","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66996164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.14300/mnnc.2023.18056
Sergey Ermakov, Oleg Belokon, Elena Anatolyevna Grishko, Alexey Pavlovich Kornev, Madina Bogatyreva, Vladimir Viktorovich Eliseev, Vladimir Viktorovich Eliseev, Diana Arturovna Gasparyan
{"title":"Association of aneurysmal subarachoid hemorrhage outcomes with the surgical treatment techniqu","authors":"Sergey Ermakov, Oleg Belokon, Elena Anatolyevna Grishko, Alexey Pavlovich Kornev, Madina Bogatyreva, Vladimir Viktorovich Eliseev, Vladimir Viktorovich Eliseev, Diana Arturovna Gasparyan","doi":"10.14300/mnnc.2023.18056","DOIUrl":"https://doi.org/10.14300/mnnc.2023.18056","url":null,"abstract":"","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135909483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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