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Multiple Renal Arteries with an Ascending Upward Renal Vein of the Right Kidney: a Case Report 多肾动脉伴右肾上行肾静脉1例
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I1.493
S. Al-Shibli
ABSTRACT As it is known; the majority of the human subjects has two renal arteries arising from the abdominal aorta; each will supply one kidney but in 30% of individuals, certain variations can be found. Accessory renal arteries constitute the most common and clinically important of these variations. For our case report, we are presenting one of these different variations that can be found in the blood supply of the kidneys. During dissecting the abdomen of an approximately 65 years-old male cadaver, multiple variations were found. There were double right renal arteries with prehilar branching of the upper renal artery. We found also that the right renal vein ascended upwards obliquely before ending in the lateral aspect of the inferior vena cava. Variation in the renal vessels is relatively common, especially multiple renal arteries, and can go smoothly without any abnormalities with the function of the kidney, but in some situations like renal transplantations, vascular reconstructions, and various surgical and radiological diagnostic techniques, the study of the anatomy of these variations is of crucial importance to decrease the patient morbidity during surgical procedures. KEYWORDS: Renal artery, renal vein, anatomical variation.
众所周知;大多数人有两条起源于腹主动脉的肾动脉;每个人都会提供一个肾脏,但在30%的个体中,可以发现某些变异。副肾动脉是这些变异中最常见和临床上重要的。在我们的病例报告中,我们将介绍在肾脏血液供应中发现的这些不同变化中的一种。在解剖一具大约65岁男性尸体的腹部时,发现了多种变异。右肾动脉双支,上肾动脉门前分支。我们还发现,右肾静脉斜向上上升,在下腔静脉外侧结束。肾血管的变异是比较常见的,尤其是多动脉肾,并且可以顺利进行,没有任何异常的肾脏功能,但在某些情况下,如肾移植,血管重建,以及各种外科和放射诊断技术,这些变异的解剖研究是至关重要的,以减少患者在手术过程中的发病率。关键词:肾动脉、肾静脉、解剖变异。
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引用次数: 0
'I can't pray' - The spiritual needs of Malaysian Muslim patients suffering from depression “我不能祈祷”——马来西亚穆斯林抑郁症患者的精神需求
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V15I1.415
A. Mr, Saini Sm, Nasrin N, Bahari R, Sharip S
Introduction : The mainstay of treatment of depression relies on pharmacological and psychological treatments. On top of that, evidence also recognizes the vital role of spirituality for human wellness which leads to growing interest in its utilization to treat depression. However, research on spirituality among Muslims in relation to depression is relatively scarce. The aim of this study is to explore the understanding of spirituality among Muslim patients with depression, and to explore their spiritual needs. Methods : This is a qualitative study conducted on 10 depressed Muslim patients at the UKM Medical Centre. Purposive sampling was done to ensure diversity of subjects. Individual in-depth interviews were conducted using semi-structured questionnaire guidelines. The data were transcribed verbatim and analysed using a thematic approach. Result : Out of 10 patients, almost all of them expressed spiritual needs. Two major themes emerged in relation to the spiritual needs which are (i) religious needs; need for worship, religious knowledge and guidance, religious reminders, and (ii) existential needs; need for calmness, sensitivity and empathy, self-discipline, certainty, hope , physical help, ventilate and meaning of illness. These needs are essential for patients during the time of crisis. Conclusion: The majority of patients expressed spiritual needs which are required during the process of recovery and this provides an opportunity to incorporate spiritual approaches in the treatment of depression. However, more studies are needed to demonstrate its scientific basis and to design an effective psycho-spiritual treatment modality so that the ‘holistic’ or ‘bio-psychosocial-spiritual’ treatment can be integrated by health care professionals to those in need.
引言:抑郁症的治疗主要依靠药物和心理治疗。除此之外,有证据还认识到精神对人类健康的重要作用,这导致人们对利用精神治疗抑郁症越来越感兴趣。然而,关于穆斯林精神与抑郁症之间关系的研究相对较少。本研究旨在探讨穆斯林抑郁症患者对精神的理解,并探讨他们的精神需求。方法:这是一项在UKM医疗中心对10名抑郁症穆斯林患者进行的定性研究。进行了有目的的抽样以确保受试者的多样性。采用半结构化问卷指南进行个人深入访谈。数据被逐字转录,并使用专题方法进行分析。结果:在10例患者中,几乎所有患者都表达了精神需求。与精神需求有关的两个主要主题是:(一)宗教需求;崇拜、宗教知识和指导、宗教提醒的需求,以及(ii)生存需求;需要冷静、敏感和同理心、自律、确定性、希望、身体帮助、通风和疾病的意义。在危机时期,这些需求对患者来说至关重要。结论:大多数患者表达了康复过程中所需的精神需求,这为将精神方法纳入抑郁症的治疗提供了机会。然而,还需要更多的研究来证明其科学基础,并设计一种有效的心理-精神治疗模式,以便卫生保健专业人员能够将“整体”或“生物-心理-精神”治疗与有需要的人相结合。
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引用次数: 6
Pilomatrixoma: A Diagnostic Pitfall on Fine-Needle Aspiration Cytology of Benign ‘Neck Metastases’ 毛基质瘤:细针穿刺细胞学诊断良性“颈部转移瘤”的一个缺陷
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I2.481
Z. A. Asha’ari, Muhd Izani Shiyuti, Kahairi Abdullah, Arfahiza Selimin, K. Sathananthar
Pilomatrixoma is a benign tumour that originates from the matrix of the hair root. This rare tumour is usually managed by the dermatologists. The commonest location of this tumour is in the head and neck region; hence, it can be encountered by any doctors with interest in this area. When presented in the neck, this hard tumour may pose a diagnostic challenge. A case report of pilomatrixoma misdiagnosed as a metastatic neck disease from fine-needle aspiration cytology is presented. The mistake in the diagnosis has led to a more aggressive and high morbidity surgery than necessary. It is important that head and neck doctors be aware of this condition and includes it in the differential diagnosis of hard masses presenting in the neck.
毛瘤是一种良性肿瘤,起源于发根基质。这种罕见的肿瘤通常由皮肤科医生治疗。这种肿瘤最常见的部位是头颈部;因此,任何对这一领域感兴趣的医生都可能遇到这种情况。当出现在颈部时,这种坚硬的肿瘤可能会对诊断提出挑战。本文报告一例细针穿刺细胞学诊断为转移性颈部疾病的毛质瘤。诊断上的错误导致了比必要的更具攻击性和高发病率的手术。重要的是,头颈部医生要意识到这种情况,并将其纳入颈部硬块的鉴别诊断中。
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引用次数: 0
Median Nerve Compression by Gouty Tophi: A Case Report 痛风性Tophi压迫正中神经1例
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V14I1.461
I. Raffael, S. Rajesh
We describe a case of median nerve compression by gouty tophi. This is a rare condition and presented with loss of function with paraesthesia of both hands in addition to multiple tophis. Surgery was chosen for immediate relief, where a debulking of left flexor digitorum superficialis with decompression of carpal tunnel was done and resulted in improvement of symptoms but became complicated due to inadequate physiotherapy.
我们描述了一例痛风性托皮压迫正中神经的病例。这是一种罕见的情况,表现为功能丧失,双手感觉异常,此外还有多处托皮。选择手术立即缓解,通过腕管减压去除左指浅屈肌,症状得到改善,但由于理疗不足而变得复杂。
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引用次数: 2
New Coumarinic Azo-Derivatives of Metoclopramide and Diphenhydramine: Synthesis and In Vitro Testing for Cholinesterase Inhibitory Effect and Protection Ability Against Chlorpyrifos 甲氧氯普胺和苯海拉明新香豆素偶氮衍生物的合成及其对毒死蜱胆碱酯酶抑制和保护作用的体外测试
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I1.486
Ahmed A. J. Mahmood, Yasser Fakri Mustafa, M. Abdulstaar
ABSTRACT Introduction: This study aims to synthesize new coumarin azo compounds of metoclopramide and diphenhydramine and to evaluate their in vitro cholinesterase inhibitory effects and protection abilities against chlorpyrifos. Methods: Two series of azo coumarin compounds were synthesized. Series I compound resulted from the diazotization of metoclopramide and then coupling with coumarin and 4-methyl coumarin to give compounds 1 and 2 respectively. Series II compound resulted from the diazotization of 7-aminocoumarin and 7-amino 4-methyl coumarin and then coupling with diphenhydramine to give compounds 3 and 4 respectively. The new compounds were tested for their in vitro cholinesterase inhibitory effect and protection ability against chlorpyrifos using the modified Elman electrometric method. Results: Metoclopramide derivatives with coumarin show selectivity protection for ChE against chlorpyriphos inhibitory effect as protect BChE and increase the inhibition of the AChE, or the opposite. Conclusion: Diphenhydramine derivatives with coumarin show more protective ability for both BChE and AChE as one of them shows the maximum protection for all concentration. However, the other derivative shows different manner as the low concentrations act as metoclopramide derivatives while the high concentration act as first diphenhydramine derivative (protect both AChE and BChE). KEYWORDS: Coumarinic azo-derivatives, metoclopramide, diphenhydramine, cholinesterase, chlorpyrifos.
摘要简介:本研究旨在合成新的甲氧氯普胺和苯海拉明香豆素偶氮化合物,并评价其体外胆碱酯酶抑制作用和对毒死蜱的保护能力。方法:合成了两个偶氮香豆素系列化合物。系列化合物由甲氧氯普胺重氮化后与香豆素和4-甲基香豆素偶联得到化合物1和2。系列II化合物是由7-氨基香豆素和7-氨基4-甲基香豆素重氮化,然后与苯海拉明偶联得到化合物3和4。采用改进的Elman电滴定法检测新化合物体外胆碱酯酶抑制作用和对毒死蜱的保护能力。结果:甲氧氯普胺类香豆素衍生物对乙酰胆碱酯具有选择性保护作用,对氯吡虫啉的抑制作用可能是保护BChE,增加对乙酰胆碱酯的抑制作用,或相反。结论:苯海拉明与香豆素衍生物对BChE和AChE均有较强的保护作用,其中一种对所有浓度的保护作用均最大。然而,其他衍生物表现出不同的方式,低浓度作为甲氧氯普胺衍生物,而高浓度作为苯海拉明第一衍生物(同时保护AChE和BChE)。关键词:香豆素偶氮衍生物、甲氧氯普胺、苯海拉明、胆碱酯酶、毒死蜱
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引用次数: 22
Conserved Peptide with Therapeutic Potential to Overcome Nasopharyngeal Carcinoma 具有治疗鼻咽癌潜力的保守肽
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I1.490
M. Rifa’i, S. Widyarti, N. Widodo
ABSTRACT Nasopharyngeal carcinoma (NPC) is a squamous-cell carcinoma that arises in the upper lining epithelium of the nasopharynx. In this study, conserved peptide (Ulin-1) of Epstein-Barr virus constructed by Biomodelling and Biocomputation was tested for its ability to stimulate B cells to produce specific antibodies. Spleen cells were isolated and cultured with anti-CD3 and lipopolysaccharide (LPS), and treated or not treated with Ulin-1. Cell culture was harvested six days after incubation and analyzed by flow cytometry. Here, we demonstrated the ability of Ulin-1 to stimulate B cells to produce specific antibodies. The results of this study illustrate the importance of Ulin-1 engineered by Biomodelling and Biocomputation as both active and passive immunization agents against nasopharyngeal cancer. KEYWORDS: Nasopharyngeal carcinoma, Ulin-1, gp 350/220, in vitro.
鼻咽癌(NPC)是一种鳞状细胞癌,发生在鼻咽部的上衬上皮。本研究通过生物建模和生物计算构建eb病毒的保守肽(Ulin-1),测试其刺激B细胞产生特异性抗体的能力。分离脾细胞,用抗cd3和脂多糖(LPS)培养,用Ulin-1处理或不处理。培养6天后收获细胞,用流式细胞术分析。在这里,我们证明了Ulin-1刺激B细胞产生特异性抗体的能力。本研究结果说明了通过生物建模和生物计算工程设计的Ulin-1作为鼻咽癌主动和被动免疫剂的重要性。关键词:鼻咽癌,Ulin-1, gp 350/220,体外
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引用次数: 2
Controlling Dengue: An uphill task? 控制登革热:一项艰巨的任务?
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V14I1.442
N. M. Amjad
Mosquito-borne dengue viral fever is one of the fastest spreading global health hazards of recent times. Although it has been widespread especially in the tropics, dengue came into prominence since the early 1950’s following the epidemic in south East Asia. The commonest presentation of Dengue Fever is characterized by high fever, severe headaches, muscle pain and skin rash. This is the primary form and is less serious than the deadly secondary form referred to as Dengue hemorrhagic fever. The latter mainly affects most Asian and Latin American countries and has become a leading cause of hospitalization and death among children in these regions.1 It is estimated that 390 million dengue infections occur per year of which about 25% present with clinical manifestations.
蚊媒登革热病毒热是近年来传播最快的全球健康危害之一。虽然登革热在热带地区尤其普遍,但自20世纪50年代初东南亚流行以来,登革热才引起人们的注意。登革热最常见的症状是高烧、严重头痛、肌肉疼痛和皮疹。这是主要形式,比致命的继发性登革热出血热不那么严重。后者主要影响大多数亚洲和拉丁美洲国家,并已成为这些地区儿童住院和死亡的主要原因据估计,每年发生3.9亿登革热感染,其中约25%出现临床表现。
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引用次数: 0
A case report of pyomyoma: radiological diagnosis of a potentially fatal complication of uterine leiomyoma. 子宫肌瘤的病例报告:子宫肌瘤潜在致命并发症的放射学诊断。
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V7I2.787
Mubarak My, Noordini
ABSTRACT Pyomyoma (suppurative leiomyoma) is a rare complication of uterine leiomyoma. It results from infarction and infection of a leiomyoma. It may lead to diagnostic and therapeutic difficulties with potential complications such as bacteraemia, uterine rupture, compressive effect to adjacent structures and even death. We report a case of pyomyoma based on the Ultrasound (US) and Computed Tomography (CT) findings and literature review on the subject. KEYWORDS: Pyomyoma, Leiomyoma, Ultrasound, Computed Tomography.
摘要化脓性平滑肌瘤是一种罕见的子宫平滑肌瘤并发症。它是由平滑肌瘤的梗塞和感染引起的。它可能导致诊断和治疗困难,潜在的并发症,如菌血症,子宫破裂,压迫邻近结构,甚至死亡。我们根据超声(US)和计算机断层扫描(CT)的发现和文献复习报告一例子宫肌瘤。关键词:子宫肌瘤,平滑肌瘤,超声,计算机断层扫描。
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引用次数: 3
A case of eosinophilic granulomatosis with polyangiitis (churg-strauss, EGPA) presenting with relapsed mononeuritis multiplex 嗜酸性肉芽肿病合并多血管炎(churg-strauss, EGPA) 1例,表现为复发性多发性单神经炎
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V13I1.496
Hilmi Abdullah, M. Ainon
ABSTRACT We report a case of eosinophilic granulomatosis with polyangiitis (EGPA), a rare multisystem disorder characterized by difficult-to-control asthma, hypereosinophilia and polyneuropathy. We also discuss the Five Factor Score (FFS) risk stratification strategy, which is used to quantitate the extent of the disease and guide treatment strategy. KEYWORDS: Churg-Strauss syndrome, vasculitis, mononeuritis multiplex, cyclophosphamide
我们报告一例嗜酸性肉芽肿病合并多血管炎(EGPA),这是一种罕见的多系统疾病,以难以控制的哮喘、嗜酸性粒细胞增多和多神经病变为特征。我们还讨论了五因子评分(FFS)风险分层策略,该策略用于量化疾病的程度并指导治疗策略。关键词:丘格-施特劳斯综合征,血管炎,多发性单神经炎,环磷酰胺
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引用次数: 0
Prediction model for peak expiratory flow among children in Kocaeli, Turkey 土耳其Kocaeli儿童呼气流量峰值预测模型
Q4 Medicine Pub Date : 2020-11-09 DOI: 10.31436/IMJM.V7I2.782
Z. Gundogdu, O. Gundogdu
Objective: To evaluate Peak Expiratory Flow (PEF) values in Turkish children between the ages 6 and 14 years old according to height, gender and age. Methods: Data was obtained from public health screening days in primary care practice on 1439 children. Peak expiratory flow (PEF) was measured for each child with a Mini Wright Peak Flow Meter. The study was assessed to find a correlation between heights, age and PEF values in children. Results: In our study, PEF values increased significantly with age and height in both genders. According to our results, the equation for prediction of PEF was calculated for girls as (7.37 × age [years])+ (3.02 × height [cm]) – 222.1 (p < .001, r= 0.83) and for boys (7.92 × age [years])+ (3.13 × height [cm]) – 230.9 (p < .001, r =0.83). Conclusions: The PEF values are statistically significant associated with age and height for girls and boys. The prediction equations specifically developed for children in Kocaeli can be used in clinical practice and these equations may help clinicians to better characterize individual or population airway responsiveness.
目的:根据身高、性别和年龄评估6 - 14岁土耳其儿童呼气流量峰值(PEF)值。方法:收集1439名儿童在初级保健实践中公共健康筛查日的数据。使用Mini Wright峰值流量仪测量每个儿童的呼气峰值流量(PEF)。这项研究的评估目的是发现儿童身高、年龄和PEF值之间的相关性。结果:在我们的研究中,PEF值随年龄和身高的增加而显著增加。根据我们的结果,女孩的PEF预测方程为(7.37 ×年龄[年])+ (3.02 ×身高[cm]) - 222.1 (p < 0.001, r= 0.83),男孩为(7.92 ×年龄[年])+ (3.13 ×身高[cm]) - 230.9 (p < 0.001, r= 0.83)。结论:女孩和男孩的PEF值与年龄和身高有统计学意义。Kocaeli专门为儿童开发的预测方程可以用于临床实践,这些方程可以帮助临床医生更好地表征个体或群体气道反应性。
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引用次数: 1
期刊
International Medical Journal Malaysia
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