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Using of Laplacian Re-decomposition image fusion algorithm for glioma grading with SWI, ADC, and FLAIR images 利用拉普拉斯再分解图像融合算法对SWI、ADC和FLAIR图像进行胶质瘤分级
IF 0.4 Q3 Medicine Pub Date : 2021-12-01 DOI: 10.2478/pjmpe-2021-0031
Amir Khorasani, M. Tavakoli, M. Saboori
Abstract Introduction: Based on the tumor’s growth potential and aggressiveness, glioma is most often classified into low or high-grade groups. Traditionally, tissue sampling is used to determine the glioma grade. The aim of this study is to evaluate the efficiency of the Laplacian Re-decomposition (LRD) medical image fusion algorithm for glioma grading by advanced magnetic resonance imaging (MRI) images and introduce the best image combination for glioma grading. Material and methods: Sixty-one patients (17 low-grade and 44 high-grade) underwent Susceptibility-weighted image (SWI), apparent diffusion coefficient (ADC) map, and Fluid attenuated inversion recovery (FLAIR) MRI imaging. To fuse different MRI image, LRD medical image fusion algorithm was used. To evaluate the effectiveness of LRD in the classification of glioma grade, we compared the parameters of the receiver operating characteristic curve (ROC). Results: The average Relative Signal Contrast (RSC) of SWI and ADC maps in high-grade glioma are significantly lower than RSCs in low-grade glioma. No significant difference was detected between low and high-grade glioma on FLAIR images. In our study, the area under the curve (AUC) for low and high-grade glioma differentiation on SWI and ADC maps were calculated at 0.871 and 0.833, respectively. Conclusions: By fusing SWI and ADC map with LRD medical image fusion algorithm, we can increase AUC for low and high-grade glioma separation to 0.978. Our work has led us to conclude that, by fusing SWI and ADC map with LRD medical image fusion algorithm, we reach the highest diagnostic accuracy for low and high-grade glioma differentiation and we can use LRD medical fusion algorithm for glioma grading.
摘要简介:根据肿瘤的生长潜力和侵袭性,胶质瘤通常被分为低级别和高级别两类。传统上,组织取样被用来确定胶质瘤的等级。本研究旨在评估Laplacian Re-decomposition (LRD)医学图像融合算法用于高级磁共振成像(MRI)图像胶质瘤分级的效率,并引入胶质瘤分级的最佳图像组合。材料与方法:61例患者(低分级17例,高分级44例)行MRI敏感性加权像(SWI)、表观扩散系数(ADC)图和流体衰减反转恢复(FLAIR)成像。为了融合不同的MRI图像,采用LRD医学图像融合算法。为了评估LRD在胶质瘤分级中的有效性,我们比较了受试者工作特征曲线(ROC)的参数。结果:高级别胶质瘤SWI和ADC图的平均相对信号对比度(RSC)明显低于低级别胶质瘤的RSC。FLAIR图像显示低级别和高级别胶质瘤之间无显著差异。在我们的研究中,SWI和ADC图上低级别和高级别胶质瘤分化的曲线下面积(AUC)分别为0.871和0.833。结论:采用LRD医学图像融合算法融合SWI和ADC图谱,可将低、高级胶质瘤分离的AUC提高到0.978。我们的工作使我们得出结论,通过融合SWI和ADC地图与LRD医学图像融合算法,我们对低级别和高级别胶质瘤分化的诊断准确率最高,我们可以使用LRD医学融合算法进行胶质瘤分级。
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引用次数: 3
Feasibility of output quality assurance considering gantry angle using “Stealth Chamber” 考虑龙门角度的“隐身腔”输出质量保证的可行性
IF 0.4 Q3 Medicine Pub Date : 2021-12-01 DOI: 10.2478/pjmpe-2021-0035
H. Miura, Fumika Takeichi, Tsubasa Enosaki, K. Yamada, S. Ozawa, Y. Nagata
Abstract Purpose: This study was conducted to demonstrate the feasibility of X-ray output constancy quality assurance (QA) of a linear accelerator for various gantry angles using the Stealth Chamber. Methods: The X-ray output constancy of a Varian TrueBeam STx was evaluated under various gantry angles and a 10 × 10 cm2 field size using a Stealth Chamber. Specifically, 10X and 10X-flattening-filter-free beams with dose rates of 600 and 2400 monitor units (MU)/min, respectively, were used. The Stealth Chamber was attached to the gantry head, and irradiation was performed every 45° for gantry angles of 0-315°. To evaluate the variations in the output constancy with respect to the gantry angle, the acquired values were normalized to the value corresponding to a 0° gantry angle. The obtained results were utilized to determine the correction factors for all gantry angles. To verify the correction factors, additional measurements were performed for five days. Results: The maximum variation in the output constancy measurement relative to the output constancy at a 0° gantry angle was found to be approximately 4.0% for both energy beams at a gantry angle of 180°. Furthermore, the measured values were dependent on the gantry angle. Upon applying the correction factor, the variation in the output constancy with respect to the gantry angle was less than 0.5%. Conclusions: Output constancy QA using the Stealth Chamber for various gantry angles was found to be feasible with the application of a correction factor.
摘要目的:研究利用隐身室对直线加速器进行不同门架角度x射线输出恒定质量保证(QA)的可行性。方法:在不同的门架角度和10 × 10 cm2的视场尺寸下,使用隐身室评估瓦里安TrueBeam STx的x射线输出常数。具体来说,使用剂量率分别为600和2400监测单位(MU)/min的10X和10X无平坦滤波光束。隐身室附在龙门头上,在0-315°的龙门角范围内,每45°照射一次。为了评估输出常数相对于龙门角的变化,将获得的值归一化为对应于0°龙门角的值。利用所得结果确定了所有龙门角度的修正系数。为了验证校正因子,进行了5天的额外测量。结果:在门架角度为180°时,两束能量束的输出常数测量值相对于0°门架角度时的输出常数的最大变化约为4.0%。此外,测量值依赖于龙门角度。在应用校正因子后,输出常数相对于龙门角的变化小于0.5%。结论:应用校正因子,采用隐身腔对不同龙门角度的输出恒定性质量保证是可行的。
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引用次数: 1
Monte Carlo Calculation of linear attenuation coefficients and photon scattering properties of novel concretes loaded with Osmium, Iridium and Barite nanoparticles 含锇、铱和重晶石纳米粒子混凝土线性衰减系数和光子散射特性的蒙特卡罗计算
IF 0.4 Q3 Medicine Pub Date : 2021-12-01 DOI: 10.2478/pjmpe-2021-0034
Samira Keramat Jou, A. Mesbahi, R. Zamiri, F. Seyednejad
Abstract Introduction: Recent studies have shown that the use of high-density nanoparticles (NPs) in concrete composition improves its radiation shielding properties. In the present study, the linear attenuation coefficients and photon scattering properties of newly developed high-density Nano-concretes have been calculated using the MCNPX Monte Carlo code. Material and methods: The shielding properties of Nano-concretes containing 10%, 20%, and 30% weight percentage of Osmium, Iridium and Barite NPs (100 nm) as well as ordinary concrete were investigated. The 6 and 18 MV photon beams of Varian Linac and 60Co photons were used for simulation. Photon scattering flux was calculated for all Nano-concretes with 30 wt% of NPs and ordinary concrete at different angles. Results: In general, by adding Iridium, Osmium and Barite NPs to ordinary concrete, the linear attenuation coefficients increased. Despite a lower density relative to Iridium and Osmium, Nano-concretes containing Barite exhibited a higher linear attenuation coefficient due to their higher electron density. Conclusions: The results revealed a dependence between the scattered photon flux and the effective atomic number of Nano-concretes. With increasing the atomic number of fillers, the intensity of the scattered photon flux enlarged. Also, the scattered flux was higher for all types of concretes at 180 degrees relative to other angles.
摘要:近年来的研究表明,在混凝土成分中使用高密度纳米颗粒(NPs)可以提高混凝土的辐射屏蔽性能。本文利用MCNPX蒙特卡罗程序计算了新研制的高密度纳米混凝土的线性衰减系数和光子散射特性。材料与方法:研究了含有10%、20%、30%重量百分比锇、铱、重晶石纳米粒子(100 nm)的纳米混凝土与普通混凝土的屏蔽性能。采用瓦里安直线加速器的6 MV和18 MV光子束和60Co光子进行模拟。计算了NPs质量分数为30%的纳米混凝土和普通混凝土在不同角度下的光子散射通量。结果:一般情况下,普通混凝土中添加铱、锇和重晶石NPs后,线性衰减系数增大。尽管与铱和锇相比,重晶石的密度较低,但由于其较高的电子密度,含有重晶石的纳米混凝土表现出较高的线性衰减系数。结论:散射光子通量与纳米混凝土的有效原子序数之间存在一定的相关性。随着填料原子序数的增加,散射光子通量的强度增大。所有类型的混凝土在180度处的散射通量均高于其他角度。
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引用次数: 2
Dose calculation accuracy for photon small fields in treatment planning systems with comparison by Monte Carlo simulations 治疗计划系统中光子小场的剂量计算精度与蒙特卡罗模拟的比较
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0022
Mojtaba Abazarfard, P. Azadeh, A. Mostaar
Abstract Purpose: Advanced radiation therapy techniques use small fields in treatment planning and delivery. Small fields have the advantage of more accurate dose delivery, but with the cost of some complications in dosimetry. Different dose calculation algorithms imported in various treatment planning systems (TPSs) which each of them has different accuracy. Monte Carlo (MC) simulation has been reported as one of the accurate methods for calculating dose distribution in radiation therapy. The aim of this study was the evaluation of TPS dose calculation algorithms in small fields against 2 MC codes. Methods: A linac head was simulated in 2 MC codes, MCNPX, and GATE. Then three small fields (0.5×0.5, 1×1 and 1.5×1.5 cm2) were simulated with 2 MC codes, and also these fields were planned with different dose calculation algorithms in Isogray and Monaco TPS. PDDs and lateral dose profiles were extracted and compared between MC simulations and dose calculation algorithms. Results: For 0.5×0.5 cm2 field mean differences in PDDs with MCNPX were 2.28, 4.6, 5.3, and 7.4% and with GATE were -0.29, 2.3, 3 and 5% for CCC, superposition, FFT and Clarkson algorithms respectively. For 1×1 cm2 field mean differences in PDDs with MCNPX were 1.58, 0.6, 1.1 and 1.4% and with GATE were 0.77, 0.1, 0.6 and 0.9% for CCC, superposition, FFT and Clarkson algorithms respectively. For 1.5×1.5 cm2 field mean differences in PDDs with MCNPX were 0.82, 0.4, 0.6 and -0.4% and with GATE were 2.38, 2.5, 2.7 and 1.7% for CCC, superposition, FFT and Clarkson algorithms respectively. Conclusions: Different dose calculation algorithms were evaluated and compared with MC simulation in small fields. Mean differences with MC simulation decreased with the increase of field sizes for all algorithms.
目的:先进的放射治疗技术在治疗计划和递送中使用小范围。小视场具有更精确的剂量传递的优点,但代价是剂量学中的一些并发症。在不同的治疗计划系统(tps)中引入不同的剂量计算算法,每个算法都具有不同的精度。蒙特卡罗(MC)模拟已被报道为计算放射治疗中剂量分布的精确方法之一。本研究的目的是针对2个MC代码评估小范围TPS剂量计算算法。方法:用2种MC编码、MCNPX和GATE模拟直线头部。然后用2个MC代码模拟了三个小场(0.5×0.5、1×1和1.5×1.5 cm2),并在Isogray和Monaco TPS中采用不同的剂量计算算法对这些小场进行了规划。提取pdd和侧位剂量分布,并与MC模拟和剂量计算算法进行比较。结果:0.5×0.5 cm2范围内,CCC、叠加、FFT和Clarkson算法与MCNPX的pdd平均差异分别为2.28、4.6、5.3和7.4%,与GATE的pdd平均差异分别为-0.29、2.3、3和5%。对于1×1 cm2, CCC、叠加、FFT和Clarkson算法与MCNPX的pdd平均差异分别为1.58、0.6、1.1和1.4%,与GATE的pdd平均差异为0.77、0.1、0.6和0.9%。对于1.5×1.5 cm2区域,CCC、叠加、FFT和Clarkson算法与MCNPX的pdd平均差异分别为0.82、0.4、0.6和-0.4%,与GATE的pdd平均差异分别为2.38、2.5、2.7和1.7%。结论:对不同剂量计算算法进行了评价,并与MC模拟在小范围内进行了比较。各算法与MC模拟的平均差异随场大小的增加而减小。
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引用次数: 1
Quantitative and dosimetric analysis for treating synchronous bilateral breast cancer using two radiotherapy planning techniques 两种放疗计划技术治疗同步双侧乳腺癌的定量和剂量学分析
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0024
Ö. Mermut, Aysun Ata, D. Trabulus
Abstract Objective: We compared mono-isocenter and dual-isocenter plans in synchronous bilateral breast cancer (SBBC), which is defined as tumours occurring simultaneously in both breasts, and evaluated the effects of these differences in plans on organs-at-risk (OARs). Materials and methods: We evaluated 10 women with early stage, nod negative (Tis-2N0M0) SBBC. The treatment dose was determined to be 50 Gy. We used mean dose and VXGy to evaluate the OARs. To evaluate the effectiveness of treatment plans, Homogeneity index (HI), conformity index (CI) and sigma index (SI) and monitor units (MU) of monoisocenter (MIT) and dual-isocenter (DIT) plans were compared. During bilateral breast planning, for the single-centre plan, the isocenter was placed at the center of both breasts at a depth of 3-4 cm. For the two-center plan, dual-isocenters were placed on the right and left breasts. Results: No significant difference between the techniques in terms of the scope of the target volume was observed. Statistically significant results were not achieved in MIT and DIT plans for OARs. Upon comparing MIT and DIT, the right-side monitor unit (MU) value in DIT (p = 0.011) was statistically significantly lower than that in MIT. Upon comparing right-left side MIT and DIT, the MU value (p = 0.028) was significantly lower in DIT than MIT. Conclusion: SBBC irradiation is more complex than unilateral breast radiotherapy. No significant difference between both techniques and OARs was observed. However, we recommend MIT as a priority technique due to the ability to protect OARs, ease of administration during treatment, and the fact that the patient stays in the treatment unit for a shorter period of time.
摘要目的:我们比较了同步双侧乳腺癌(SBBC)的单等中心和双等中心方案,SBBC被定义为同时发生在双侧乳房的肿瘤,并评估这些方案差异对危险器官(OARs)的影响。材料与方法:对10例早期淋巴结阴性(Tis-2N0M0) SBBC患者进行评估。治疗剂量为50戈瑞。我们用平均剂量和VXGy评价OARs。为评价治疗方案的有效性,比较单等中心(MIT)和双等中心(DIT)方案的均匀性指数(HI)、符合性指数(CI)、适格指数(SI)和监护单位(MU)。在双侧乳房计划时,对于单中心计划,将等中心放置在双侧乳房的中心,深度为3-4 cm。对于双中心方案,双等中心放置在左右乳房上。结果:两种方法在靶体积范围上无明显差异。在OARs的MIT和DIT计划中没有取得统计学上显著的结果。MIT与DIT比较,DIT组右侧监护单位(MU)值(p = 0.011)显著低于MIT组(p = 0.011)。比较左、右侧MIT与DIT, DIT的MU值显著低于MIT (p = 0.028)。结论:SBBC放疗比单侧乳腺放疗更为复杂。两种技术与OARs之间无显著差异。然而,我们推荐MIT作为优先技术,因为它能够保护桨叶,在治疗过程中易于给药,而且患者在治疗单位停留的时间较短。
{"title":"Quantitative and dosimetric analysis for treating synchronous bilateral breast cancer using two radiotherapy planning techniques","authors":"Ö. Mermut, Aysun Ata, D. Trabulus","doi":"10.2478/pjmpe-2021-0024","DOIUrl":"https://doi.org/10.2478/pjmpe-2021-0024","url":null,"abstract":"Abstract Objective: We compared mono-isocenter and dual-isocenter plans in synchronous bilateral breast cancer (SBBC), which is defined as tumours occurring simultaneously in both breasts, and evaluated the effects of these differences in plans on organs-at-risk (OARs). Materials and methods: We evaluated 10 women with early stage, nod negative (Tis-2N0M0) SBBC. The treatment dose was determined to be 50 Gy. We used mean dose and VXGy to evaluate the OARs. To evaluate the effectiveness of treatment plans, Homogeneity index (HI), conformity index (CI) and sigma index (SI) and monitor units (MU) of monoisocenter (MIT) and dual-isocenter (DIT) plans were compared. During bilateral breast planning, for the single-centre plan, the isocenter was placed at the center of both breasts at a depth of 3-4 cm. For the two-center plan, dual-isocenters were placed on the right and left breasts. Results: No significant difference between the techniques in terms of the scope of the target volume was observed. Statistically significant results were not achieved in MIT and DIT plans for OARs. Upon comparing MIT and DIT, the right-side monitor unit (MU) value in DIT (p = 0.011) was statistically significantly lower than that in MIT. Upon comparing right-left side MIT and DIT, the MU value (p = 0.028) was significantly lower in DIT than MIT. Conclusion: SBBC irradiation is more complex than unilateral breast radiotherapy. No significant difference between both techniques and OARs was observed. However, we recommend MIT as a priority technique due to the ability to protect OARs, ease of administration during treatment, and the fact that the patient stays in the treatment unit for a shorter period of time.","PeriodicalId":53955,"journal":{"name":"Polish Journal of Medical Physics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76389407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The effective and water-equivalent diameters as geometrical size functions for estimating CT dose in the thoracic, abdominal, and pelvic regions 有效直径和水当量直径作为几何尺寸函数用于估计胸部、腹部和骨盆区域的CT剂量
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0026
Winda Kusuma Dewi, C. Anam, E. Hidayanto, A. Nitasari, G. Dougherty
Abstract Purpose: The aim of this work was to establish the relationships of patient size in terms of effective diameter (Deff) and water-equivalent diameter (Dw) with lateral (LAT) and anterior-posterior (AP) dimensions in order to predict the specific patient dose for thoracic, abdominal, and pelvic computed tomography (CT) examinations. Methods: A total of 47 thoracic images, 79 abdominal images, and 50 pelvic images were analyzed in this study. The patient’s images were retrospectively collected from Dr. Kariadi and Kensaras Hospitals, Semarang, Indonesia. The slices measured were taken from the middle of the scan range. The calculations of patient sizes (LAT, AP, Deff, and Dw) were automatically performed by IndoseCT 20b software. Deff and Dw were plotted as functions of LAT, AP, and AP+LAT. In addition, Dw was plotted as a function of Deff. Results: Strong correlations of Deff and Dw with LAT, AP, and AP+LAT were found. Stronger correlations were found in the Deff curves (R2 > 0.9) than in the Dw curves (R2 > 0.8). It was found that the average Deff was higher than the average Dw in the thoracic region, the average values were similar in the abdominal and pelvic regions. Conclusion: The current study extended the study of the relationships between Deff and Dw and the basic geometric diameter LAT, AP, and AP+LAT beyond those previously reported by AAPM. We evaluated the relationships for three regions, i.e. thoracic, abdominal, and pelvic regions. Based on our findings, it was possible to estimate Deff and Dw from only the LAT or AP dimension.
目的:本研究的目的是建立有效直径(Deff)和水当量直径(Dw)与侧位(LAT)和前后位(AP)尺寸之间的关系,以预测胸部、腹部和骨盆计算机断层扫描(CT)检查时患者的特定剂量。方法:对47张胸片、79张腹部片和50张盆腔片进行分析。患者的图像回顾性地从印度尼西亚三宝垄的Dr. Kariadi和Kensaras医院收集。测量的切片取自扫描范围的中间。采用IndoseCT 20b软件自动计算患者大小(LAT、AP、Deff、Dw)。Deff和Dw作为LAT、AP和AP+LAT的函数绘制。此外,将Dw绘制为Deff的函数。结果:Deff、Dw与LAT、AP、AP+LAT有较强相关性。Deff曲线的相关性(R2 > 0.9)强于Dw曲线(R2 > 0.8)。结果发现,胸椎区域的平均Deff高于平均Dw,腹部和骨盆区域的平均值相似。结论:本研究扩展了Deff、Dw与基本几何直径LAT、AP、AP+LAT的关系研究,超出了AAPM先前报道的范围。我们评估了三个区域的关系,即胸部、腹部和骨盆区域。基于我们的发现,仅从LAT或AP维度就可以估计Deff和Dw。
{"title":"The effective and water-equivalent diameters as geometrical size functions for estimating CT dose in the thoracic, abdominal, and pelvic regions","authors":"Winda Kusuma Dewi, C. Anam, E. Hidayanto, A. Nitasari, G. Dougherty","doi":"10.2478/pjmpe-2021-0026","DOIUrl":"https://doi.org/10.2478/pjmpe-2021-0026","url":null,"abstract":"Abstract Purpose: The aim of this work was to establish the relationships of patient size in terms of effective diameter (Deff) and water-equivalent diameter (Dw) with lateral (LAT) and anterior-posterior (AP) dimensions in order to predict the specific patient dose for thoracic, abdominal, and pelvic computed tomography (CT) examinations. Methods: A total of 47 thoracic images, 79 abdominal images, and 50 pelvic images were analyzed in this study. The patient’s images were retrospectively collected from Dr. Kariadi and Kensaras Hospitals, Semarang, Indonesia. The slices measured were taken from the middle of the scan range. The calculations of patient sizes (LAT, AP, Deff, and Dw) were automatically performed by IndoseCT 20b software. Deff and Dw were plotted as functions of LAT, AP, and AP+LAT. In addition, Dw was plotted as a function of Deff. Results: Strong correlations of Deff and Dw with LAT, AP, and AP+LAT were found. Stronger correlations were found in the Deff curves (R2 > 0.9) than in the Dw curves (R2 > 0.8). It was found that the average Deff was higher than the average Dw in the thoracic region, the average values were similar in the abdominal and pelvic regions. Conclusion: The current study extended the study of the relationships between Deff and Dw and the basic geometric diameter LAT, AP, and AP+LAT beyond those previously reported by AAPM. We evaluated the relationships for three regions, i.e. thoracic, abdominal, and pelvic regions. Based on our findings, it was possible to estimate Deff and Dw from only the LAT or AP dimension.","PeriodicalId":53955,"journal":{"name":"Polish Journal of Medical Physics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82420698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dosimetry audit of the CyberKnife accelerator with the SHANE phantom 用SHANE幻象对射波刀加速器进行剂量学审计
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0025
M. Szymański, M. Piziorska, Oskar Madetko, W. Ślusarczyk-Kacprzyk, W. Bulski
Abstract Introduction: The aim of this study was to propose a dosimetric audit of the CyberKnife system. Dosimetry audit is an important part of the quality assurance process in radiotherapy. Most of the proposed dosimetric audits are dedicated to classical medical accelerators. Currently, there is no commonly implemented scheme for conducting a dosimetric audit of the CyberKnife accelerator. Material and methods: To verify the dosimetric and geometric parameters of the entire radiotherapy process, as is required in E2E test procedure, the CIRS SHANE anthropomorphic phantom was used. A tomography with a resolution of 1.5 mm was prepared, five PTVs (Planning Target Volume) of different volumes were drawn; approximately: 88 cm3, 44 cm3, 15 cm3, 7 cm3, 1.5 cm3. Five treatment plans were made using the 6D Skull tracking method, FIXED collimators, RayTracing algorithm. Each treatment plan was verified in a slab Phantom, with a PinPoint chamber. The dose was measured by an ionization chamber type TM31010 Semiflex, placed in the center area of the target. Results: The result of the QA verification in slab phantom was up to 5,0%. The percentage difference for the measurement in the SHANE phantom was: 4.29%, -1.42%, -0.70%, 1.37%, -1.88% respectively for the targets: 88 cm3, 44 cm3, 15 cm3, 7 cm3, 1.5 cm3. Conclusions: By analyzing various approaches to small-field dosimetry audits in the literature, it can be assumed that the proposed CyberKnife dosimetric audit using the SHANE phantom is an appropriate method of verification of the radiotherapy process. Particular attention should be paid to the target volume, adjusting it to the system capabilities.
摘要简介:本研究的目的是提出射波刀系统的剂量学审计。剂量学审核是放射治疗质量保证过程的重要组成部分。大多数拟议的剂量学审计都专门针对经典的医疗加速器。目前,对射波刀加速器进行剂量学审计没有普遍实施的方案。材料和方法:根据E2E测试程序的要求,为了验证整个放疗过程的剂量学和几何参数,我们使用了CIRS SHANE人形假体。制作分辨率为1.5 mm的层析成像,绘制5个不同体积的ptv (Planning Target Volume);大约:88 cm3, 44 cm3, 15 cm3, 7 cm3, 1.5 cm3。采用6D颅骨跟踪法、FIXED准直器、RayTracing算法制定5种治疗方案。每个治疗方案都在带有PinPoint腔室的平板Phantom中进行验证。剂量测量是通过一个电离室型TM31010 Semiflex,放置在目标的中心区域。结果:板坯模型的QA验证率为5.0%。靶:88 cm3, 44 cm3, 15 cm3, 7 cm3, 1.5 cm3, SHANE幻影测量的百分比差异分别为4.29%,-1.42%,-0.70%,1.37%,-1.88%。结论:通过分析文献中各种小场剂量学审计的方法,可以假设使用SHANE幻象的射波刀剂量学审计是一种适当的放射治疗过程验证方法。应该特别注意目标容量,并根据系统功能对其进行调整。
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引用次数: 0
Contribution of soil in the annual effective dose due to radon in the air of some dwellings in the city of Karbala, Iraq 伊拉克卡尔巴拉市一些住宅空气中氡对土壤年有效剂量的贡献
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0028
A. Hashim, L. A. Najam, F. Aljomaily
Abstract Introduction: The radon isotopes are not as significant as (222Rn) due to the decay of the natural radionuclides (235U), (232Th) and (238U) due to their short half-life, at most. (222Rn) can be classified as among the most harmful radioactive elements in the world. Material and method: In this analysis, the closed-can technique was used with solid-state nuclear track detectors (CR-39). After forty days of closed dosimeter buried in the soil of the garden, and ninety days from the closed position in the air of some dwellings were collected dosimeter and stripped of nuclear detectors impact of closed groups. For 8 hours, CR-39 detectors were chemically etched by (6.25 N) NaOH solution at 70°C and then registered within an optical microscope. Result: The levels of soil radon concentrations ranged from 28.44±0.58 to 479.76±2.43 Bq/m3 with a mean value of 220.33±1.64 Bq/m3, while the concentration of radon in the air of certain dwellings varied from (1.95±0.27 to 46.82±0.75) Bq/m3 with an average value of 21.51±0.54 Bq/m3. In comparison, the annual effective dose attributed to radon in soil ranged from 0.71±0.09 mSv/y to 12.10±0.38 mSv/y with an average value of 5.55±0.261 mSv/y, while the annual effective dose in air differed from (0.04±0.02 mSv/y) to (1.18±0.12 mSv/y) with an average value of (0.60±0.09 mSv/y). Conclusion: Neglecting the effects of other radon sources, the percentage share of the annual effective dose due to radon in soil measured in the air home, ranged from 0.005±0.001 to 0.453±0.074 with an average value of 0.130±0.040. Weak correlation between concentrations of radon in households and soil air. But roughly speaking, one can say that in soil air every 1000 Bq/m3 and 1000 mSv/y contributes around 130 Bq/m3 and 130 mSv/y in indoor air.
摘要简介:氡同位素的重要程度不如(222Rn),这是由于天然放射性核素(235U)、(232Th)和(238U)的半衰期短,最多会发生衰变。(222Rn)可以被列为世界上最有害的放射性元素之一。材料和方法:在本分析中,封闭罐技术被用于固体核径迹探测器(CR-39)。经过40天的封闭剂量计埋在花园的土壤中,以及90天的封闭位置在一些住宅的空气中收集剂量计并剥离核探测器影响的封闭组。用(6.25 N) NaOH溶液在70°C下化学蚀刻CR-39探测器8小时,然后在光学显微镜下记录。结果:土壤氡浓度变化范围为28.44±0.58 ~ 479.76±2.43 Bq/m3,平均值为220.33±1.64 Bq/m3;部分住宅空气氡浓度变化范围为(1.95±0.27 ~ 46.82±0.75)Bq/m3,平均值为21.51±0.54 Bq/m3。土壤氡的年有效剂量范围为0.71±0.09 mSv/y ~ 12.10±0.38 mSv/y,平均值为5.55±0.261 mSv/y;空气氡的年有效剂量范围为(0.04±0.02 mSv/y) ~(1.18±0.12 mSv/y),平均值为(0.60±0.09 mSv/y)。结论:在忽略其他氡源影响的情况下,空气家庭土壤氡年有效剂量所占的百分比范围为0.005±0.001 ~ 0.453±0.074,平均值为0.130±0.040。家庭氡浓度与土壤空气之间的相关性较弱。但粗略地说,土壤空气中每1000 Bq/m3和1000 mSv/y对室内空气的贡献约为130 Bq/m3和130 mSv/y。
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引用次数: 0
Trend and prediction of COVID-19 outbreak in Iran: SEIR and ANFIS model 伊朗新冠肺炎疫情趋势与预测:SEIR和ANFIS模型
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0029
Sajad Shafiekhani, T. H. Khalilabad, S. Rafiei, V. Sadeghi, A. Jafari, N. Gheibi
Abstract Background: Mathematical and predictive modeling approaches can be used in COVID-19 crisis to forecast the trend of new cases for healthcare management purposes. Given the COVID-19 disease pandemic, the prediction of the epidemic trend of this disease is so important. Methods: We constructed an SEIR (Susceptible-Exposed-Infected-Recovered) model on the COVID-19 outbreak in Iran. We estimated model parameters by the data on notified cases in Iran in the time window 1/22/2020 – 20/7/2021. Global sensitivity analysis is performed to determine the correlation between epidemiological variables and SEIR model parameters and to assess SEIR model robustness against perturbation to parameters. We Combined Adaptive Neuro-Fuzzy Inference System (ANFIS) as a rigorous time series prediction approach with the SEIR model to predict the trend of COVID-19 new cases under two different scenarios including social distance and non-social distance. Results: The SEIR and ANFIS model predicted new cases of COVID-19 for the period February 7, 2021, till August 7, 2021. Model predictions in the non-social distancing scenario indicate that the corona epidemic in Iran may recur as an immortal oscillation and Iran may undergo a recurrence of the third peak. Conclusion: Combining parametrized SEIR model and ANFIS is effective in predicting the trend of COVID-19 new cases in Iran.
背景:在新冠肺炎危机中,可以采用数学和预测建模方法预测新病例趋势,为医疗管理提供依据。鉴于2019冠状病毒病大流行,预测该疾病的流行趋势非常重要。方法:以伊朗新冠肺炎疫情为研究对象,构建易感-暴露-感染-恢复模型。我们根据2020年1月22日至2021年7月20日期间伊朗通报病例的数据估计模型参数。进行全局敏感性分析以确定流行病学变量与SEIR模型参数之间的相关性,并评估SEIR模型对参数扰动的稳健性。我们将自适应神经模糊推理系统(ANFIS)作为严格的时间序列预测方法与SEIR模型相结合,对社会距离和非社会距离两种不同情景下的新冠肺炎病例趋势进行了预测。结果:SEIR和ANFIS模型预测了2021年2月7日至2021年8月7日期间的新发病例。在非社交距离情景下的模型预测表明,伊朗的冠状病毒疫情可能会以一种永久的振荡形式再次出现,伊朗可能会再次出现第三个高峰。结论:参数化SEIR模型与ANFIS相结合可有效预测伊朗新发病例趋势。
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引用次数: 2
Determination of DQE as a quantitative assessment of detectors in digital mammography: Measurements and calculation in practice 确定DQE作为数字乳房x线照相术中检测器的定量评估:实践中的测量和计算
IF 0.4 Q3 Medicine Pub Date : 2021-09-01 DOI: 10.2478/pjmpe-2021-0027
A. Wysocka-Rabin, M. Dobrzyńska, K. Pasicz, W. Skrzyński, E. Fabiszewska
Abstract Introduction: Advances in digital detector technology and methods of image presentation in digital mammography now offer the possibility of implementing mathematical assessment methods to quantitative image analysis. The aim of this work was to develop new software to simplify the application of the existing international standard for DQE in digital mammography and show in detail how it can be applied, using a Siemens Mammomat Inspiration as a model. Material and methods: Consistent with the IEC standard a 2 mm Al filter at the tube exit and images in DICOM format as raw data, without applying any additional post-processing were used. Measurements were performed for W/Rh anode/filter combination and different tube voltage values (26 ÷ 34 kV) without any anti-scatter grid. To verify new software doses ranging from 20-600 µGy were used in measurements. Exposure (air kerma) was measured using a calibrated radiation meter (Piranha Black 457, RTI Electronics AB, Sweden). MTF was determined, using an edge test device constructed specifically for this work. Results: It has been demonstrated that with the new software the DQE can be measured with the accuracy required by the international standard IEC 62220-1-2. DQE has been presented as a function of spatial frequency for W/Rh anode/filter combination and different tube voltage. Conclusions: New software was used successfully to analyze image quality parameters for the Siemens Mammomat Inspiration detector. This was done on the basis of an internationally accepted methodology. In the next step, mammographs with different detector types can be compared.
摘要引言:数字乳房x线摄影中数字探测器技术和图像呈现方法的进步,为定量图像分析提供了实施数学评估方法的可能性。这项工作的目的是开发新的软件,以简化DQE在数字乳房x线摄影中的现有国际标准的应用,并详细展示如何应用它,使用西门子Mammomat Inspiration作为模型。材料和方法:使用符合IEC标准的2毫米铝滤光片在管出口和图像的DICOM格式作为原始数据,没有进行任何额外的后处理。在没有防散射网格的情况下,对W/Rh阳极/滤波器组合和不同管电压值(26 ~ 34 kV)进行了测量。为了验证在测量中使用的新软件剂量范围为20-600µGy。使用校准辐射计(Piranha Black 457, RTI Electronics AB,瑞典)测量暴露量(空气热)。MTF被确定,使用一个专门为这项工作建造的边缘测试装置。结果:应用该软件可达到国际标准IEC 62220-1-2所要求的DQE测量精度。DQE是W/Rh阳极/滤波器组合和不同管电压下空间频率的函数。结论:应用新软件成功地分析了西门子奶妈启发检测器的图像质量参数。这是根据国际公认的方法进行的。下一步,可以比较不同探测器类型的乳房x光片。
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引用次数: 1
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Polish Journal of Medical Physics and Engineering
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