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Bias in the Diagnosis of Borderline Personality Disorder Among Sexual- and Gender-Minority Persons: Results From a Vignette-Based Experiment 性少数群体和性别少数群体在边缘型人格障碍诊断中的偏见:基于小插曲的实验结果
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-09-14 DOI: 10.1177/21677026241267954
Craig Rodriguez-Seijas, Marley Warren, Preetam Vupputuri, Skylar Hawthorne
Sexual- and gender-minority (SGM) individuals are diagnosed with borderline personality disorder (BPD) more than cisgender heterosexuals. Using a large sample of mental-health practitioners in the United States and Canada ( N = 426), we examined bias in the diagnosis of BPD. Mental-health practitioners were randomly assigned to receive one of three clinical vignettes (cisgender heterosexual man, cisgender gay man, or transgender woman) and asked to provide psychiatric diagnoses based on the vignette. Mental-health practitioners demonstrated a predilection to diagnose BPD when presented with the transgender vignette (odds ratio [ OR] = 1.99, p = .01) but not the cisgender-gay vignette ( OR = 1.34, p = .29) compared with practitioners presented the cisgender-heterosexual vignette. Psychiatrists, mental-health counselors, and clinical social workers were significantly more inclined to diagnose BPD than psychologists, although reasons for underdiagnosis differed across groups. These findings bear important implications for future training given the nature of the mental-health workforce in the United States.
性取向和性别少数群体(SGM)被诊断为边缘型人格障碍(BPD)的人数多于顺性别异性恋者。通过对美国和加拿大的心理健康从业人员进行大样本抽样(N = 426),我们研究了边缘型人格障碍诊断中的偏差。心理健康从业人员被随机分配到三个临床小故事(顺性别异性恋男性、顺性别同性恋男性或变性女性)中的一个,并被要求根据小故事提供精神病学诊断。与变性异性恋小插图相比,心理健康从业者在看到变性小插图时倾向于诊断 BPD(几率比[OR] = 1.99,p = .01),而在看到同性异性恋小插图时则不倾向于诊断 BPD(OR = 1.34,p = .29)。精神科医生、心理健康顾问和临床社会工作者对 BPD 的诊断倾向明显高于心理学家,尽管不同群体诊断不足的原因各不相同。鉴于美国心理健康工作队伍的性质,这些发现对未来的培训具有重要意义。
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引用次数: 0
Opening the Black Box: The Underlying Working Mechanisms in Virtual-Reality Exposure Therapy for Anxiety Disorders 打开黑盒:虚拟现实暴露疗法治疗焦虑症的基本工作机制
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-09-14 DOI: 10.1177/21677026241267945
Sara Scheveneels, Iris Engelhard, Katharina Meyerbröker
Although research on virtual-reality (VR) exposure therapy (VRET) in anxiety disorders has primarily focused on effectiveness and acceptability, the underlying working mechanisms have received scant attention. To fill this knowledge gap, we discuss potential theoretical underpinnings of VRET based on three dominant theoretical accounts on exposure: inhibitory-learning theory (expectancy violation), emotional-processing theory (habituation), and self-efficacy theory. Whereas theoretically speaking, habituation and self-efficacy seem plausible candidate mechanisms to explain the effects of VRET, the role of expectancy violation is less straightforward. Because of the simulated nature of VR, some feared outcomes cannot occur, and therefore, possibilities to violate expectancies about their occurrence may be compromised. Empirical evidence on the working mechanisms of VRET is scarce and has important limitations. Avenues for future research are provided. Insights into the mechanisms of VRET not only are of theoretical importance but also can provide theory-based directions to optimize the application of VRET.
尽管有关虚拟现实(VR)暴露疗法(VRET)治疗焦虑症的研究主要集中在有效性和可接受性方面,但其潜在的工作机制却很少受到关注。为了填补这一知识空白,我们基于三种主流的暴露理论,讨论了虚拟现实暴露疗法的潜在理论基础:抑制学习理论(预期违规)、情绪加工理论(习惯化)和自我效能理论。从理论上讲,习惯化和自我效能似乎是解释 VRET 效果的合理候选机制,而预期违规的作用则不那么简单。由于虚拟现实的模拟性质,一些令人担忧的结果是不可能发生的,因此,违反对这些结果发生的预期的可能性可能会受到影响。关于 VRET 工作机制的经验证据很少,而且有很大的局限性。本文提供了未来研究的途径。洞察虚拟现实与情感体验的机制不仅具有重要的理论意义,还能为优化虚拟现实与情感体验的应用提供基于理论的方向。
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引用次数: 0
Testing a Reward-Processing Model of Negative Urgency in Women With and Without Binge Eating 测试有无暴食女性的负紧迫性奖赏加工模型
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-09-14 DOI: 10.1177/21677026241267996
Sarah E. Racine, Vittoria Trolio, Alexia E. Miller, Adrienne Mehak, Ege Bicaker, Samantha Wilson, Stephen D. Benning
Negative urgency (i.e., the tendency to act impulsively when experiencing negative affect) is robustly associated with psychopathology, but the mechanisms underlying negative urgency and its relation to mental health are not well understood. In addition to interfering with cognitive control, negative emotions may lead to impulsive behavior by enhancing reward processing of desired stimuli. In this study, we tested an emotion-enhanced reward-processing model of negative urgency in 153 women who spanned the spectrum of binge-eating severity. Participants completed two experimental tasks under both stressful- and relaxed-mood conditions while physiological, behavioral, and self-report indices of reward processing of palatable food were assessed. Contrary to hypotheses, reward processing of food was not heightened when stressed versus relaxed either in the full sample or in participants with greater negative urgency or binge-eating frequency/severity. Findings are discussed considering study limitations and previous mechanistic work on negative urgency.
消极急迫感(即在经历消极情绪时冲动行事的倾向)与精神病理学密切相关,但消极急迫感的内在机制及其与心理健康的关系却不甚明了。除了干扰认知控制外,负面情绪还可能通过增强对期望刺激的奖赏处理而导致冲动行为。在这项研究中,我们对 153 名女性进行了测试,她们的暴饮暴食严重程度各不相同,因此我们采用了一种情绪增强奖赏加工模型来研究负性紧迫感。参与者在紧张和放松的情绪条件下完成了两项实验任务,同时对美味食物奖赏加工的生理、行为和自我报告指数进行了评估。与假设相反,无论是在全部样本中,还是在负面紧迫感更强或暴食频率/严重程度更高的参与者中,压力与放松时对食物的奖赏处理都没有增强。考虑到研究的局限性和之前关于负面紧迫感的机理研究,本文对研究结果进行了讨论。
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引用次数: 0
Additive Benefits of Individual, Relational, and Community Factors on Physical- and Mental-Health Trajectories Among Black Americans 个人、关系和社区因素对美国黑人身心健康轨迹的叠加效应
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-26 DOI: 10.1177/21677026241266580
Olutosin Adesogan, Justin A. Lavner, Sierra E. Carter, Steven R. H. Beach
Black Americans have demonstrated significant resilience in the face of stress caused by systemic oppression. This resilience is likely to stem from several factors across socioecological levels, including those internal to the individual (assets) and those external to the individual (resources), but existing work has yet to consider these within an integrated framework. To address this gap, in the current study, we used longitudinal data from 692 Black adults living in the rural southeastern United States to examine the univariate and multivariate effects of individual (religiosity and spirituality), relational (romantic partner support, general social support), and community (neighborhood support) factors on trajectories of depressive symptoms, sleep problems, and general health. Findings revealed univariate and multivariate effects on health, providing evidence of additive benefits from these assets and resources. Greater consideration of strengths and supports across socioecological systems may help inform enhanced preventive interventions for and promote health equity among Black Americans.
美国黑人在面对系统性压迫造成的压力时表现出了强大的复原力。这种抗压能力可能源于多个社会生态层面的因素,包括个人内部因素(资产)和个人外部因素(资源),但现有工作尚未在一个综合框架内考虑这些因素。为了填补这一空白,在本研究中,我们使用了 692 名生活在美国东南部农村地区的黑人成年人的纵向数据,研究了个人(宗教信仰和灵性)、关系(恋爱伴侣支持、一般社会支持)和社区(邻里支持)因素对抑郁症状、睡眠问题和一般健康的单变量和多变量影响。研究结果显示了对健康的单变量和多变量影响,为这些资产和资源带来的附加益处提供了证据。更多地考虑整个社会生态系统的优势和支持可能有助于为美国黑人加强预防干预提供信息,并促进美国黑人的健康公平。
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引用次数: 0
Is Dosage of a Meditation App Associated With Changes in Psychological Distress? It Depends on How You Ask 冥想应用程序的剂量与心理压力的变化有关吗?这取决于您如何提问
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-26 DOI: 10.1177/21677026241266567
Simon B. Goldberg, Ashley D. Kendall, Matthew J. Hirshberg, Cortland J. Dahl, Inbal Nahum-Shani, Richard J. Davidson, Bethany C. Bray
Despite growing popularity, associations between dosage and outcomes in meditation-app interventions have not been established. We examined this relationship using a range of operationalizations of dosage (e.g., minutes of use, days of use, number and type of activities completed) and strategies for modeling outcomes (e.g., ordinary least squares regression, multilevel modeling, latent class analysis). We used data from a recently completed randomized controlled trial that tested a meditation app ( N = 662; 80.4% with elevated depression/anxiety) that included psychological distress as its preregistered primary outcome. Across 41 models, whether an association was detected and the shape and direction of this association varied. Although several models indicated that higher dosage was associated with larger decreases in psychological distress, many models failed to show this relationship, and some even showed the opposite. These results may have implications for optimizing and studying dosage in meditation apps and for open-science practices.
尽管冥想应用干预越来越受欢迎,但其剂量与结果之间的关系尚未确定。我们使用一系列剂量操作(如使用分钟数、使用天数、完成活动的数量和类型)和结果建模策略(如普通最小二乘法回归、多层次建模、潜类分析)对这种关系进行了研究。我们使用了最近完成的一项随机对照试验的数据,该试验测试了一款冥想应用程序(N = 662;80.4% 患有抑郁症/焦虑症),并将心理困扰作为其预先登记的主要结果。在 41 个模型中,是否检测到关联以及这种关联的形式和方向各不相同。虽然有几个模型表明,剂量越大,心理压力的下降幅度就越大,但许多模型并没有显示出这种关系,有些模型甚至显示出相反的关系。这些结果可能对冥想应用程序中剂量的优化和研究以及开放科学实践有影响。
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引用次数: 0
A Bayesian Longitudinal Network Analysis of Panic-Disorder Symptoms and Respiratory Biomarkers 恐慌症症状与呼吸系统生物标志物的贝叶斯纵向网络分析
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-26 DOI: 10.1177/21677026241263330
Galen P. Cassidy, Mikael Rubin, Santiago Papini, Michael J. Telch
The network theory of psychopathology is gaining popularity as a conceptualization of psychological disorders that may aid the identification of mechanisms of therapeutic change. However, many existing networks do not consider other relevant variables beyond the symptoms themselves. We present a large-scale ( n = 1,873), longitudinal Bayesian network analysis of panic disorder using the symptom items from the Panic Disorder Severity Scale (PDSS) and two respiratory biomarkers (respiration rate and end-tidal CO2) collected during routine monitoring of a capnometry-guided respiratory intervention (CGRI). Our findings offer support for avoidance and fear of panic as drivers of subsequent panic-disorder symptoms over the 4-week course of treatment. Moreover, respiration rate but not end-tidal CO2 was associated with downstream PDSS symptoms. These findings provide further evidence supporting the role of respiratory biomarkers in the maintenance of panic disorder and some support for normalization of dysfunctional breathing as one therapeutic mechanism governing CGRI.
精神病理学网络理论作为一种心理障碍的概念化理论,正日益受到人们的欢迎,它可以帮助确定治疗改变的机制。然而,许多现有的网络并没有考虑症状本身之外的其他相关变量。我们利用恐慌症严重程度量表(PDSS)中的症状项目以及在对帽式呼吸引导的呼吸干预(CGRI)进行常规监测时收集的两个呼吸生物标志物(呼吸频率和潮气末二氧化碳),对恐慌症进行了大规模(n = 1,873)、纵向贝叶斯网络分析。我们的研究结果表明,在为期 4 周的治疗过程中,回避和对恐慌的恐惧是随后出现恐慌症症状的驱动因素。此外,呼吸频率(而非潮气末二氧化碳)与下游 PDSS 症状相关。这些研究结果进一步证明了呼吸生物标志物在维持惊恐障碍中的作用,并在一定程度上支持将呼吸功能障碍恢复正常作为 CGRI 的一种治疗机制。
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引用次数: 0
Social Identity Mapping and Psychotic Disorders: Understanding the Relationships Between Social Identity Features, Self-Esteem, and Quality of Life 社会身份映射与精神障碍:了解社会身份特征、自尊和生活质量之间的关系
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-26 DOI: 10.1177/21677026241263522
Maev Conneely, Domenico Giacco, Lauren M. Hickling, Stefan Priebe, Janelle M. Jones
Having more social connections is related to better quality of life in people with psychosis. However, little is known about the nature of these social connections or whether the personal significance of social connections matters for quality of life. We aimed to fill this gap by surveying 200 people with psychosis using social identity mapping (SIM), which allows people to name their groups, roles, and relationships and how they feel about these. SIM names were categorized into 10 groups, with “activities” (39%) and “family” (14%) being most common; “patient” (3%), “politics” (2%), and “local residence” (1%) were least common. Hierarchical regression revealed that the only variable associated with better quality of life was having a greater number of highly important connections. This was mediated by self-esteem. Clinicians and researchers should examine the potential of social identification, the internalization of social connections, as a means of improving quality of life.
拥有更多的社会关系与提高精神病患者的生活质量有关。然而,人们对这些社会关系的性质以及社会关系的个人意义是否会影响生活质量却知之甚少。我们使用社会身份图谱(SIM)对 200 名精神病患者进行了调查,旨在填补这一空白。SIM 可以让人们说出自己的团体、角色和关系,以及他们对这些团体、角色和关系的感受。SIM名称被分为10组,其中 "活动"(39%)和 "家庭"(14%)最常见;"病人"(3%)、"政治"(2%)和 "当地居住地"(1%)最不常见。层次回归显示,唯一与提高生活质量相关的变量是拥有更多高度重要的联系。自尊心在其中起到了中介作用。临床医生和研究人员应该研究社会认同的潜力,即社会关系的内在化,以此作为提高生活质量的一种手段。
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引用次数: 0
Do Polygenic Indices Capture “Direct” Effects on Child Externalizing Behavior Problems? Within-Family Analyses in Two Longitudinal Birth Cohorts 多基因指数是否能捕捉到对儿童外化行为问题的 "直接 "影响?两个纵向出生队列的家庭内分析
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-24 DOI: 10.1177/21677026241260260
Peter T. Tanksley, Sarah J. Brislin, Jasmin Wertz, Ronald de Vlaming, Natasia S. Courchesne-Krak, Travis T. Mallard, Laurel L. Raffington, Richard Karlsson Linnér, Philipp Koellinger, Abraham A. Palmer, Sandra Sanchez-Roige, Irwin D. Waldman, Danielle Dick, Terrie E. Moffitt, Avshalom Caspi, K. Paige Harden
Failures of self-control can manifest as externalizing behaviors (e.g., aggression, rule-breaking) that have far-reaching negative consequences. Researchers have long been interested in measuring children’s genetic risk for externalizing behaviors to inform efforts at early identification and intervention. Drawing on data from the Environmental Risk Longitudinal Twin Study ( N = 862 twins) and the Millennium Cohort Study ( N = 2,824 parent–child trios), two longitudinal cohorts from the United Kingdom, we leveraged molecular genetic data and within-family designs to test for genetic associations with externalizing behavior that are not affected by common sources of environmental influence. We found that a polygenic index (PGI) calculated from genetic variants discovered in previous studies of self-controlled behavior in adults captures direct genetic effects on externalizing problems in children and adolescents when evaluated with rigorous within-family designs (βs = 0.13–0.19 across development). The PGI for externalizing behavior can usefully augment psychological studies of the development of self-control.
自我控制能力的缺失会表现为外化行为(如攻击、破坏规则),从而产生深远的负面影响。长期以来,研究人员一直对测量儿童外化行为的遗传风险感兴趣,以便为早期识别和干预提供依据。利用环境风险纵向双胞胎研究(862 对双胞胎)和千禧队列研究(2824 对亲子三人组)(英国的两个纵向队列)的数据,我们利用分子遗传数据和家庭内设计来检验与外化行为的遗传关联,这些关联不受环境影响的共同来源的影响。我们发现,根据以往对成人自控行为研究中发现的基因变异计算出的多基因指数(PGI),在采用严格的家庭内设计进行评估时,可以捕捉到基因对儿童和青少年外化问题的直接影响(βs = 0.13-0.19 跨越发育过程)。外化行为的 PGI 可以有效地加强对自我控制能力发展的心理学研究。
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引用次数: 0
Characterizing Midlife-Onset Alcohol Dependence: Implications for Etiology, Prevention, and Healthy Aging 中年酒精依赖症的特征:对病因学、预防和健康老龄化的影响
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-24 DOI: 10.1177/21677026241260249
Lara Khalifeh, Avshalom Caspi, Kallisse R. Dent, HonaLee Harrington, Madeline H. Meier, Richie Poulton, Sandhya Ramrakha, Terrie E. Moffitt, Leah S. Richmond-Rakerd
We evaluated the developmental epidemiology of midlife-onset alcohol dependence (AD) in the Dunedin Study ( N = 1,037), a population-representative cohort followed across 5 decades. At ages 18, 21, 26, 32, 38, and 45, past-year AD prevalence was 11.0%, 18.4%, 13.6%, 8.1%, 9.6%, and 11.3%, respectively. As expected, relative to never-diagnosed individuals, individuals with early onset AD (first diagnosis at age 18 or age 21, prevalence = 22.9%) were distinguished by a range of early life and adult correlates. Individuals with midlife-onset AD (first diagnosis at age 38 or age 45, prevalence = 5.6%) were distinguished by fewer early life correlates, but exhibited a family history of AD and adolescent dysregulation and marijuana use. They were characterized by an array of adult correlates, including internalizing disorders, mental-health-treatment contact, criminal behavior, perceived stress, coping by drinking, lower likelihood of marriage and parenthood, and reduced preparedness for old age. They also experienced more adult alcohol-related impairment than the early onset group. Results can guide efforts to reduce midlife alcohol-related problems and support healthy aging.
我们在达尼丁研究(Dunedin Study,N = 1,037)中评估了中年酒精依赖(AD)的发展流行病学。在 18 岁、21 岁、26 岁、32 岁、38 岁和 45 岁时,过去一年的酒精依赖症发病率分别为 11.0%、18.4%、13.6%、8.1%、9.6% 和 11.3%。正如预期的那样,与从未诊断过的人相比,早发性注意力缺失症患者(首次诊断年龄为18岁或21岁,患病率=22.9%)在早期生活和成年后的一系列相关因素中脱颖而出。中年发病的注意力缺失症患者(首次确诊年龄为38岁或45岁,患病率=5.6%)的早期生活相关因素较少,但他们有注意力缺失症家族史、青春期行为失调和吸食大麻。他们具有一系列成年相关因素,包括内化障碍、接触心理健康治疗、犯罪行为、感知压力、通过饮酒来应对、结婚和为人父母的可能性较低以及对老年生活的准备不足。与早发组相比,他们在成年后也经历了更多与酒精相关的损害。研究结果可为减少中年酒精相关问题和支持健康老龄化提供指导。
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引用次数: 0
A Hierarchical Model of the Symptom-Level Structure of Psychopathology in Youth 青少年精神病理学症状层次结构的层次模型
IF 4.8 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-08-08 DOI: 10.1177/21677026241257852
Miriam K. Forbes, Ashley L. Watts, Maddison Twose, Angelique Barrett, Jennifer L. Hudson, Heidi J. Lyneham, Lauren McLellan, Nicola C. Newton, Gemma Sicouri, Cath Chapman, Anna McKinnon, Ronald M. Rapee, Tim Slade, Maree Teesson, Kristian Markon, Matthew Sunderland
More comprehensive modeling of psychopathology in youth is needed to facilitate a developmentally informed expansion of the Hierarchical Taxonomy of Psychopathology (HiTOP) model. In this study, we examined a symptom-level model of the structure of psychopathology in children and adolescents—most aged 11 to 17 years—bringing together data from large clinical, community, and representative samples ( N = 18,290) covering nearly all major forms of mental disorders and related content domains (e.g., aggression). The resulting hierarchical and dimensional model was based on the points of convergence among three statistical approaches and included 15 narrow dimensions nested under four broad dimensions of (a) internalizing, (b) externalizing, (c) eating pathology, and (d) uncontrollable worry, obsessions, and compulsions. We position these findings within the context of the existing literature and articulate implications for future research. Ultimately, these findings add to the rapidly growing literature on the structure of psychopathology in youth and move a step closer toward quantifying (dis)continuities in psychopathology’s structure across the life span.
我们需要对青少年的精神病理学进行更全面的建模,以促进精神病理学层次分类法(HiTOP)模型在发展过程中的扩展。在这项研究中,我们研究了一个儿童和青少年精神病理学结构的症状层面模型,该模型的年龄大多在 11 至 17 岁之间,我们将来自大型临床、社区和代表性样本(N = 18,290 )的数据整合在一起,涵盖了几乎所有主要形式的精神障碍和相关内容领域(如攻击性)。由此产生的分层和维度模型以三种统计方法的汇合点为基础,包括 15 个狭义维度,嵌套在 (a) 内化、(b) 外化、(c) 饮食病理学和 (d) 无法控制的担忧、强迫症和强迫症四个广义维度之下。我们将这些发现置于现有文献的背景下,并阐明了对未来研究的影响。最终,这些发现为迅速增长的有关青少年精神病理学结构的文献增添了新的内容,并朝着量化精神病理学结构在整个生命周期的(不)连续性迈进了一步。
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引用次数: 0
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Clinical Psychological Science
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