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Lifetime trauma exposure and accelerated epigenetic aging among midlife women. 中年妇女终身创伤暴露与加速表观遗传衰老。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-11-01 Epub Date: 2025-06-16 DOI: 10.1037/hea0001523
Rebecca C Thurston, Caroline Y Doyle, Cynthia D J Kusters, Yuefang Chang, Karestan Koenen, Pauline Maki, Judith E Carroll

Objective: Trauma exposure may be linked to accelerated biological aging. However, studies have largely considered childhood abuse, with limited consideration of lifetime trauma exposure, particularly for women. Furthermore, few studies have considered newer epigenetic clocks, which have enhanced links with health outcomes. Among midlife women, we investigated whether lifetime trauma exposure is associated with older epigenetic age with several generations of clocks. We explored associations between childhood maltreatment and epigenetic age and racial differences in associations between trauma and epigenetic age.

Method: Two hundred sixteen women (Mage = 59 years, 83% non-Hispanic White, 13% Black, and 4% other race/ethnicities) underwent physical measures, questionnaires to assess lifetime trauma exposure, and a blood draw. A subset of 123 women completed childhood maltreatment measures. Extrinsic epigenetic age, GrimAge, principal component-based PhenoAge, and DunedinPACE were calculated. Clocks were residualized for age and Z-scored for analysis. Associations between trauma and epigenetic age were estimated in linear regression (covariates race, education, body mass index, and estimated cell counts). Interactions by race were tested.

Results: Relative to women without trauma exposure, those with ≥ 2 lifetime traumas had older epigenetic age, GrimAge, 1: B (SE) = 0.15 (0.15), p = .31, 2+: B (SE) = 0.39 (0.13), p = .004; DunedinPACE, 1: B (SE) = 0.23 (0.12), p = .07, 2+: B (SE) = 0.33 (0.11), p = .003. Childhood sexual abuse was also associated with older epigenetic age, GrimAge: B (SE) = 0.56 (0.24), p = .021. Exploratory models suggested that trauma was related to epigenetic age primarily among Black women.

Conclusion: Among midlife women, greater lifetime trauma and possibly childhood sexual abuse were associated with older epigenetic age, independent of chronologic age. Black women may be particularly affected. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:创伤暴露可能与生物老化加速有关。然而,研究主要是考虑儿童虐待,很少考虑终身创伤暴露,特别是对妇女。此外,很少有研究考虑到更新的表观遗传时钟,它与健康结果的联系有所增强。在中年妇女中,我们研究了终身创伤暴露是否与几代时钟的表观遗传年龄有关。我们探讨了儿童虐待与表观遗传年龄之间的关系,以及创伤与表观遗传年龄之间的种族差异。方法:216名女性(年龄59岁,83%为非西班牙裔白人,13%为黑人,4%为其他种族/民族)接受了身体测量、评估终身创伤暴露的问卷调查和抽血。123名妇女完成了儿童虐待措施。计算了外在表观遗传年龄、GrimAge、基于主成分的表型年龄和DunedinPACE。时钟对年龄和z评分进行了残差分析。创伤与表观遗传年龄之间的关联通过线性回归(协变量为种族、教育程度、体重指数和估计细胞计数)进行估计。测试了种族间的相互作用。结果:与无创伤暴露的女性相比,有≥2次终身创伤的女性表观遗传年龄较大,grmage, 1: B (SE) = 0.15 (0.15), p = 0.31, 2+: B (SE) = 0.39 (0.13), p = 0.004;DunedinPACE, 1: B (SE) = 0.23 (0.12), p = . 07, 2 +: B (SE) = 0.33 (0.11), p = .003。儿童期性侵也与表观遗传年龄较大相关,grmage: B (SE) = 0.56 (0.24), p = 0.021。探索性模型表明,创伤主要与黑人女性的表观遗传年龄有关。结论:在中年妇女中,较大的终身创伤和可能的儿童期性虐待与较大的表观遗传年龄相关,而与实际年龄无关。黑人女性可能受到的影响尤其严重。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
Narratives, emotions, and slogans: Community co-designed campaigns to recruit black blood donors from the general U.K. population. 叙述、情感和口号:社区共同设计了从英国普通人群中招募黑人献血者的活动。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-11-01 Epub Date: 2025-07-10 DOI: 10.1037/hea0001525
Eamonn Ferguson, Erin Dawe-Lane, Richard Mills, Krystal Oteng-Attakora, Emanuele Di Angelantonio, Angela M Wood, Barbara Masser, Abiola Okubanjo

Background: Blood is an essential medicine, and to deliver effective health care, blood services need to attract donors who represent the diverse demographics of health care users. At present, there is a substantial shortfall of Black donors. We report how a novel community-based co-designed arts-based approach to encourage Black donors generalizes to the wider U.K.

Population:

Method: The co-design process involved four stages: (a) needs identification (n = 42 Black people) to identify where, when and with whom Black people discussed blood donation; (b) workshops to co-design arts-based interventions (n = 12: Black people-professional actors/artists and lay people); (c) test and refinement of the narratives (n = 1); and (d) evaluation using an online experiment to provide a quantitative and qualitative evaluation of the co-designed narratives relative to a slogan-based campaign in terms of affect (mediator) and two outcomes (willingness to donate and encourage others to donate; n = 826: 345 Black people, 481 White people).

Results: Four script narratives were produced: (a) comedy-challenging misconceptions; (b) reciprocity-donating for mutual benefit; (c) donor-recipient-linking donors and recipients; and (d) sliding doors-reversing a timeline to provide a positive outcome. All four narratives were evaluated positively. For White people, the slogan-based campaign enhanced both outcomes via positive affect. For Black people, the donor-recipient narrative enhanced both outcomes via positive affect.

Conclusion: All communities positively rated the co-designed arts-based approaches and showed specific benefits for encouraging Black donors. Blood services should consider using co-designed arts-based approaches. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

背景:血液是一种基本药物,为了提供有效的卫生保健,血液服务需要吸引代表卫生保健使用者不同人口统计数据的献血者。目前,黑人捐助者严重短缺。我们报告了一种新颖的基于社区的共同设计的以艺术为基础的方法如何推广到更广泛的英国人口中,以鼓励黑人献血者:方法:共同设计过程包括四个阶段:(a)需要识别(n = 42名黑人),以确定黑人在何地、何时以及与谁讨论献血;(b)共同设计以艺术为基础的干预措施的讲习班(n = 12:黑人——专业演员/艺术家和非专业人士);(c)检验和改进叙述(n = 1);(d)使用在线实验进行评估,从影响(中介)和两个结果(捐赠意愿和鼓励他人捐赠)的角度,对基于口号的活动的共同设计叙事进行定量和定性评估;n = 826: 345名黑人,481名白人)。结果:产生了四种脚本叙事:(a)挑战喜剧的误解;(b)互惠——为互惠而捐赠;(c)将捐助国和受援国联系起来;(d)滑动门——反转时间线以提供积极的结果。所有四种叙述都得到了积极的评价。对于白人来说,以口号为基础的运动通过积极的影响增强了这两种结果。对于黑人来说,供者-受者叙事通过积极影响增强了这两种结果。结论:所有社区都积极评价共同设计的基于艺术的方法,并显示出鼓励黑人捐助者的具体好处。血液服务机构应考虑采用共同设计的基于艺术的方法。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
Predicting the preventable: Social drivers of health on pediatric readmissions and emergency department visits. 预测可预防:儿童再入院和急诊科就诊健康的社会驱动因素。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-11-01 Epub Date: 2025-06-02 DOI: 10.1037/hea0001529
Kristen A Torres, Doris Valenzuela-Araujo, Michael A Harris, Nathan F Dieckmann, Joanna Galindo, Louise Elaine Vaz, David V Wagner

Objective: This study aimed to examine the extent to which pediatric emergency department visits and admissions are preventable and whether caregiver-reported social factors predict future preventable visits.

Method: Caregivers of hospitalized children (N = 249) completed a predischarge survey regarding health care utilization and social drivers of health (e.g., adverse childhood experiences and experiences of racial discrimination). Chart reviews were conducted 365 days postdischarge to capture the presence and frequency of acute medical events (AMEs; i.e., readmissions and emergency department visits). Three methods of determining the preventability of AMEs were used to examine the relationship between preventable AMEs and medical status, demographic characteristics, and social drivers of health.

Results: Of the youth who experienced an AME, over half (67%) experienced one or more events classified as "preventable" by at least one method. Statistically significant predictors associated with preventable events included age under 1 (OR = 4.17), complex/chronic medical status (OR = 3.03), other children in the home with health concerns (OR = 1.85), and the presence of a neurocognitive disorder (OR = 2.97). Higher caregiver education (incidence rate ratio [IRR] = 0.31) was related to fewer preventable events overall. Child mental health condition (IRR = 18.62), having a deceased caregiver (IRR = 4.35), and child experiences of racial or ethnic discrimination (IRR = 6.01) were related to more preventable readmissions.

Conclusion: A substantial number of AMEs may be preventable. Caregiver reports of social factors should be included in risk assessments to inform tailored interventions and discharge plans based on unique family characteristics. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:本研究旨在探讨儿科急诊科就诊和入院可预防的程度,以及护理人员报告的社会因素是否能预测未来可预防的就诊。方法:对249例住院儿童的护理人员进行出院前医疗保健利用和健康的社会驱动因素(如童年不良经历和种族歧视经历)调查。出院后365天进行图表审查,以了解急性医疗事件的存在和频率(AMEs;即再入院和急诊室就诊)。采用三种确定AMEs可预防性的方法来检验可预防AMEs与医疗状况、人口特征和健康的社会驱动因素之间的关系。结果:在经历AME的青少年中,超过一半(67%)经历了至少一种方法可以“预防”的一个或多个事件。与可预防事件相关的具有统计学意义的预测因子包括1岁以下(OR = 4.17)、复杂/慢性医疗状况(OR = 3.03)、家中其他有健康问题的儿童(OR = 1.85)和存在神经认知障碍(OR = 2.97)。护理人员教育程度越高(发病率比[IRR] = 0.31),总体上可预防事件越少。儿童心理健康状况(IRR = 18.62)、有已故照顾者(IRR = 4.35)和儿童种族或民族歧视经历(IRR = 6.01)与更多可预防的再入院相关。结论:相当数量的AMEs是可以预防的。护理人员的社会因素报告应包括在风险评估中,以根据独特的家庭特征为量身定制的干预措施和出院计划提供信息。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
A disposition-belief-motivation framework for COVID-19 boosters: Prospective tests in a U.S. sample. COVID-19助推器的性格-信念-动机框架:美国样本的前瞻性测试。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-11-01 Epub Date: 2025-06-09 DOI: 10.1037/hea0001526
Tim Bogg, Elizabeth Milad, Olivia Godfrey

Objective: The present study tested a novel integration of prospective associations of sociodemographic factors, dispositional tendencies, primary vaccine intention, illness beliefs and experiences, preventive beliefs and behaviors, contextual vaccine-related influences, primary vaccination propensity, and subjective numeracy with subsequent COVID-19 booster vaccination.

Method: The preregistered study used a stratified online U.S. sample (N = 500). Four assessments were aligned with "15 days to slow the spread" in March 2020 (baseline), the vaccine authorization and major case/mortality surge during December 2020 and January 2021 (Time 2), the third major/case mortality surge during September-November 2021 (Time 3), and the immediate postpandemic period during May-July 2023 (Time 4).

Results: Path modeling showed greater education at baseline, and perceived risk of infection, flu vaccine history, and primary vaccination at Time 3 were prospective predictors of booster vaccination propensity at Time 4. The effect of greater educational attainment was maintained, in part, by stronger flu vaccine history. The use of reliable COVID-19 vaccine information sources at Time 3 indirectly predicted booster vaccination propensity via primary vaccination propensity. Finally, greater trait openness and less conservative political beliefs showed serially indirect prospective associations with booster vaccination via stronger intermediating vaccine intention and then via stronger primary vaccination propensity.

Conclusions: The integrative psychosocial model identified direct and indirect pathways from antecedent characteristics to booster vaccination, providing further direction for the framing of health provider, public health, and media communications for promoting booster vaccination and mitigating related misinformation. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:本研究检验了社会人口因素、倾向倾向、初次接种意愿、疾病信念和经历、预防信念和行为、疫苗相关的背景影响、初次接种倾向和主观计算能力与随后的COVID-19加强疫苗接种的前瞻性关联的新整合。方法:预注册研究采用分层在线美国样本(N = 500)。四项评估与2020年3月的“15天减缓传播”(基线)、2020年12月和2021年1月的疫苗授权和主要病例/死亡率激增(时间2)、2021年9月至11月的第三次主要病例/死亡率激增(时间3)以及2023年5月至7月的大流行后时期(时间4)相一致。结果:路径模型显示基线时受教育程度较高,感知感染风险、流感疫苗史和第3次接种是第4次加强疫苗接种倾向的前瞻性预测因素。较高教育程度的影响得以维持,部分原因是更强的流感疫苗接种史。在时间3使用可靠的COVID-19疫苗信息来源通过初次接种倾向间接预测加强疫苗接种倾向。最后,更大的性格开放性和更少的保守政治信仰通过更强的中间疫苗意向和更强的初次疫苗倾向显示出与加强疫苗接种的一系列间接前瞻性关联。结论:综合社会心理模型确定了从先前特征到加强疫苗接种的直接和间接途径,为卫生服务提供者、公共卫生和媒体沟通的框架提供了进一步的方向,以促进加强疫苗接种和减轻相关的错误信息。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
The prosocial phenotype and co-operative health protective behaviors: Insights from COVID-19. 亲社会表型与合作健康保护行为:来自COVID-19的启示
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-10-27 DOI: 10.1037/hea0001561
Richard Mills, Emanuele Di Angelantonio, Karen Wetherall, Seonaid Cleare, Barbara Masser, Heather McClelland, Ambrose J Melson, Claire Niedzwiedz, Daryl B O'Connor, Ronan O'Carroll, Kathryn A Robb, Elizabeth Scowcroft, Billy Watson, Angela Wood, Tiago Zortea, Rory O'Connor, Roshan Desai, Susan R Brailsford, Eamonn Ferguson

Objective: Identifying factors associated with co-operative health-protective behaviors (e.g., vaccination and social distancing) is critical during crises requiring collective action. This research examines two hypotheses in the context of the COVID-19 pandemic: (a) the situational-strength hypothesis, which predicts that the impact of prosocial preferences on repeated low-cost co-operative actions (e.g., adherence to government guidelines) is moderated by situational ambiguity (e.g., clarity of guidelines); and (b) the vaccination-altruism hypothesis, predicting prosocial individuals are more likely to undertake high-cost co-operative actions (e.g., initial COVID-19 vaccination) due to other-regarding motives.

Method: Study 1 (N = 2, 861) assessed four prosocial behaviors (blood donation, organ donor registration, monetary donation, and volunteering) and three classic co-operative games (dictator, trust, and public goods) to validate a prosocial-phenotype (PP) measure. Study 2 (N = 3, 077) utilized an eight-wave U.K. panel survey (March 2020-July 2021) to test the situational strength and vaccination-altruism hypotheses.

Results: Study 1 found that past prosocial behavior was significantly correlated with behavior in co-operative games, supporting construction of the PP measure. In Study 2, higher PP, in line with the situational-strength hypothesis, was associated with greater adherence to guidelines, but only when rules were ambiguous. Higher PP was also associated with greater stated willingness and uptake of vaccination. Although self-protection was the most common motive to vaccinate, high-PP individuals were more likely to cite protecting others and achieving herd immunity.

Conclusion: Prosociality plays a dynamic role in influencing both low- and high-cost co-operative health protective behaviors, offering insights for public health strategies in future crises. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

目标:在需要集体行动的危机期间,确定与合作保护健康行为(例如,接种疫苗和保持社会距离)相关的因素至关重要。本研究考察了COVID-19大流行背景下的两个假设:(a)情境强度假设,该假设预测亲社会偏好对重复低成本合作行动(如遵守政府指导方针)的影响会受到情境模糊性(如指导方针的清晰度)的调节;(b)疫苗接种利他主义假说,预测亲社会个体更有可能出于与他人相关的动机而采取高成本的合作行动(例如,首次接种COVID-19疫苗)。方法:研究1 (N = 2,861)评估了四种亲社会行为(献血、器官捐献登记、金钱捐赠和志愿服务)和三种经典合作游戏(独裁者、信任和公共物品)来验证亲社会表型(PP)测量。研究2 (N = 3077)利用一项八波英国小组调查(2020年3月至2021年7月)来测试情境强度和疫苗利他主义假设。结果:研究1发现过去亲社会行为与合作游戏行为显著相关,支持了PP测量的构建。在研究2中,较高的PP(符合情境强度假设)与更强的遵守准则相关,但仅在规则含糊不清的情况下。较高的PP也与更大的疫苗接种意愿和接受程度相关。尽管自我保护是接种疫苗最常见的动机,但高pp个体更有可能引用保护他人和实现群体免疫。结论:亲社会性对低成本和高成本合作健康保护行为均有动态影响,为未来危机中的公共卫生策略提供参考。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
Social identity processes affect objectively measured physical health: A systematic review and meta-analyses. 社会认同过程影响客观测量的身体健康:系统回顾和荟萃分析。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-10-27 DOI: 10.1037/hea0001552
Tegan Cruwys, Mark Stevens, Niklas K Steffens, Jan A Häusser, Samantha M Pang, Miranda Cody-Osborne, Ella Edwards-Smith, Eoin Garton, Yuang Cheng, Taylah McCluskey

Objective: A systematic review (CRD42023422237) examined the effect of social identity processes on objectively measured physical health.

Method: Eligible studies (a) quantitatively manipulated or measured social identity strength, salience, or threat, or multiple group membership, and (b) objectively measured (i.e., nonself-report) health behavior, physical health, or health-relevant biomarker. PsychINFO, PubMed, and SPORTDiscus were searched (24 September 2024). We conducted narrative synthesis, meta-analysis for sufficiently homogenous subclusters, and risk of bias assessment.

Results: The 106 studies (Ntotal = 290,816; 20 countries; published 1982-2024) were highly diverse in design and dependent variables and were grouped into five discrete clusters. First, 46 studies assessed whether threats to social identities increased acute cardiovascular reactivity, g = 0.40, 95% confidence interval (CI) = [.179, .617] (42 effects, N = 1,432). Second, 21 studies assessed whether social identity salience reduced stress biomarkers, g = -0.28, 95% CI = [-.544, -.006] (20 effects, N = 487). Third, 16 studies (too heterogenous for meta-analysis) found evidence of ingroup normative influence on health behaviors. Fourth, six studies (too heterogenous for meta-analysis) assessed social identification in health interventions; five found benefits for disease-related outcomes. Finally, 17 studies examined the protective effect of subjective (multiple) group membership on long-term health (e.g., mortality), OR = .59, 95% CI = [.385, .891] (eight effects, N = 27,985). Studies were high quality on average, although there was some evidence of publication bias.

Conclusion: Results provide evidence for both social cure and social curse predictions of the social identity approach to health. We identified five distinct ways in which social identity processes affect physical health. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:一项系统综述(CRD42023422237)探讨社会认同过程对客观测量的身体健康的影响。方法:符合条件的研究:(a)定量操纵或测量的社会认同强度、显著性或威胁性,或多群体成员,以及(b)客观测量的(即非自我报告)健康行为、身体健康或与健康相关的生物标志物。检索PsychINFO、PubMed和SPORTDiscus(2024年9月24日)。我们进行了叙述性综合,对充分同质的子群进行了荟萃分析,并进行了偏倚风险评估。结果:106项研究(Ntotal = 290,816; 20个国家;发表于1982-2024年)在设计和因变量上高度多样化,并被分为五个离散的集群。首先,46项研究评估了社会身份威胁是否会增加急性心血管反应性,g = 0.40, 95%可信区间(CI) =[。]179年,。[617](42个效应,N = 1432)。其次,21项研究评估了社会认同显著性是否降低了压力生物标志物,g = -0.28, 95% CI =[- 0.544, - 0.006](20项效应,N = 487)。第三,16项研究(过于异质而无法进行荟萃分析)发现了群体内规范对健康行为影响的证据。第四,六项研究(异质性太大,无法进行荟萃分析)评估了卫生干预措施中的社会认同;其中五项发现对疾病相关结果有益。最后,17项研究考察了主观(多重)群体成员身份对长期健康(如死亡率)的保护作用,OR = 0.59, 95% CI =[]。385年,。[891](8个效应,N = 27,985)。尽管有一些证据表明存在发表偏倚,但研究的平均质量较高。结论:研究结果为社会认同方法对健康的社会治愈和社会诅咒预测提供了证据。我们确定了社会认同过程影响身体健康的五种不同方式。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
Diabetes-related emotional distress, depressive symptoms, and continuous glucose monitoring outcomes. 糖尿病相关情绪困扰、抑郁症状和持续血糖监测结果
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-10-27 DOI: 10.1037/hea0001550
Michael Morreale, Emily C Soriano, Alyssa L Fenech, Hannah A Brownlee, Scott D Siegel, Jean-Philippe Laurenceau

Objective: The objective of this study was to examine how diabetes-related emotional distress and depressive symptoms are uniquely related to objective measures of glycemic outcomes in people with Type 2 diabetes mellitus (T2DM). Existing research demonstrates that diabetes distress is better able to account for glycemic outcomes when compared to depressive symptoms. However, few studies have focused on this comparison when assessing glycemic outcomes using continuous glucose monitoring (CGM) indices specifically in T2DM populations.

Method: Sixty-three adults diagnosed with T2DM were recruited from an outpatient endocrinology clinic. Diabetes-related emotional distress and depressive symptoms were assessed via self-report measures. Glycemic outcomes were measured using the gold standard hemoglobin A1c and 7 days of CGM data (measuring both glucose concentration levels and variation). The relationship between diabetes-related emotional distress (operationalized as a latent factor), depressive symptomatology, and glycemic outcome metrics (i.e., hemoglobin A1c and CGM-based) was evaluated using structural equation modeling.

Results: Moderate-sized associations were observed between diabetes-related emotional distress and a majority of the glycemic outcome metrics when controlling for depressive symptoms. No associations were observed between depressive symptoms and glycemic outcome metrics when controlling for diabetes-related emotional distress.

Conclusions: The findings suggest that following a T2DM diagnosis, diabetes-related emotional distress is better able to account for variance in glycemic outcomes when compared to depressive symptoms. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

目的:本研究的目的是研究糖尿病相关情绪困扰和抑郁症状与2型糖尿病(T2DM)患者血糖结局客观测量的独特关系。现有的研究表明,与抑郁症状相比,糖尿病困扰更能解释血糖升高的结果。然而,很少有研究集中在使用连续血糖监测(CGM)指标评估T2DM人群的血糖结局时进行比较。方法:从门诊内分泌科门诊招募63名确诊为2型糖尿病的成年人。通过自我报告方法评估糖尿病相关的情绪困扰和抑郁症状。使用金标准血红蛋白A1c和7天CGM数据(测量葡萄糖浓度水平和变化)测量血糖结局。使用结构方程模型评估糖尿病相关情绪困扰(作为潜在因素操作)、抑郁症状和血糖结局指标(即基于血红蛋白A1c和cgm的指标)之间的关系。结果:在控制抑郁症状时,观察到糖尿病相关情绪困扰与大多数血糖结局指标之间存在中等程度的关联。在控制糖尿病相关情绪困扰时,没有观察到抑郁症状和血糖结局指标之间的关联。结论:研究结果表明,T2DM诊断后,与抑郁症状相比,糖尿病相关的情绪困扰更能解释血糖结果的差异。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
Serial multiple mediation model of fear of cancer recurrence in patients with colorectal cancer. 结直肠癌患者肿瘤复发恐惧的串联多重中介模型
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-10-01 Epub Date: 2025-04-14 DOI: 10.1037/hea0001483
Yun-Jen Chou, Yun-Hsiang Lee, Been-Ren Lin, Jeng-Kai Jiang, Hui-Ying Yang, Hsiang-Ying Lin, Shiow-Ching Shun

Objective: The present study investigated the interrelationships among fatigue, depressive symptoms, resilience, and fear of cancer recurrence in patients with colorectal cancer.

Method: Patients were recruited from the colorectal cancer surgical outpatient departments of two medical centers in northern Taiwan. A total of 416 patients with colorectal cancer at Stages 0-III were recruited. The Fatigue Symptom Inventory, Resilience Scale, Center for Epidemiological Studies Depression Scale, and Fear of Cancer Recurrence Inventory-Short Form were adopted. The generated serial multiple mediation model was examined using the Hayes PROCESS macro V4.3 in SPSS.

Results: The patients had mild overall scores in fatigue, depressive symptoms, and fear of cancer recurrence but moderate scores in resilience. Notably, 46.6% of the patients had clinical-level scores in fear of cancer recurrence. Fear of cancer recurrence was negatively correlated with resilience and positively correlated with fatigue and depressive symptoms. Furthermore, resilience and depressive symptoms fully mediated the relationship between fatigue and fear of cancer recurrence.

Conclusions: The findings of this study underscore the pivotal roles of resilience and depressive symptoms in the relationship between fatigue and fear of cancer recurrence. Therefore, health care providers are encouraged to prioritize early assessment and the management of depressive symptoms in patients with colorectal cancer and incorporate resilience-focused interventions into their care plans. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:探讨结直肠癌患者疲劳、抑郁症状、心理恢复力与癌症复发恐惧之间的相互关系。方法:选取台湾北部两所医疗中心大肠癌外科门诊患者。总共招募了416名0-III期结直肠癌患者。采用疲劳症状量表、心理弹性量表、流行病学研究中心抑郁量表、癌症复发恐惧量表简表。生成的串行多重中介模型使用SPSS中的Hayes PROCESS宏V4.3进行检验。结果:患者在疲劳、抑郁症状和对癌症复发的恐惧方面得分为轻度,而在恢复力方面得分为中等。值得注意的是,46.6%的患者有临床水平的癌症复发恐惧评分。对癌症复发的恐惧与恢复力呈负相关,与疲劳和抑郁症状呈正相关。此外,恢复力和抑郁症状完全介导了疲劳和癌症复发恐惧之间的关系。结论:本研究的结果强调了弹性和抑郁症状在疲劳和癌症复发恐惧之间的关系中的关键作用。因此,鼓励卫生保健提供者优先考虑结肠直肠癌患者抑郁症状的早期评估和管理,并将以恢复力为重点的干预措施纳入其护理计划。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
The association of burnout and vital exhaustion with (measures of) the metabolic syndrome: A systematic review and meta-analysis. 倦怠和生命衰竭与代谢综合征(测量)的关系:一项系统回顾和荟萃分析。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-10-01 Epub Date: 2025-04-10 DOI: 10.1037/hea0001498
Sanne H M Kremers, Joline W J Beulens, Marije Strikwerda, Sharon Remmelzwaal, Linda J Schoonmade, Allard J van der Beek, Petra J M Elders, Femke Rutters

Objective: This systematic review and meta-analysis aims to investigate the association of burnout and vital exhaustion (VE) symptoms with (measures of) the metabolic syndrome (MetS).

Method: PubMed, Embase, and PsycINFO were systematically searched until April 26, 2024. Studies investigating adult populations, burnout, or VE as exposures and (measures of) MetS as outcomes were included. Data extraction and quality assessment were performed independently by two observers. If at least three independent effect measures (in at least two studies) were available per association, meta-analyses were performed using random-effects models.

Results: We included 101 studies (71% cross-sectional, 11% case-control, 13% prospective, 5% alternative) comprising 22 strong, 55 moderate, and 24 weak quality studies. Meta-analyses showed relevant but statistically nonsignificant associations of burnout and VE symptoms with higher incident (odds ratio [OR] = 1.53 [0.82, 2.87], I² = 0%) and prevalent MetS (OR = 1.28 [0.99, 1.64], I² = 85%), incident obesity (OR = 1.88 [0.81, 4.36], I² = 0%), waist-to-hip ratio (standardized mean difference = 0.62 [-0.65, 1.90], I2 = 95%), prevalent high waist circumference (OR = 1.14 [0.80, 1.62], I² = 28%), high triglycerides (OR = 1.49 [0.82, 2.71], I² = 40%), and a significantly higher prevalent hypertension (OR = 1.63 [1.44, 1.84], I2 = 51%). We found no clinically relevant associations with remaining MetS measures.

Conclusions: Burnout and VE symptoms might be associated with a higher odds of prevalent and incident MetS, however, not statistically significant. These results should be interpreted with caution due to the cross-sectional design of most studies, use of unadjusted baseline data, and substantial heterogeneity in some analyses. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:本系统综述和荟萃分析旨在探讨倦怠和生命衰竭(VE)症状与代谢综合征(MetS)的关系。方法:系统检索PubMed、Embase、PsycINFO,检索截止至2024年4月26日。研究调查了成年人群,倦怠,或VE作为暴露和(测量)MetS作为结果。数据提取和质量评估由两名观察员独立进行。如果每个关联至少有三个独立的效应测量(在至少两个研究中)可用,则使用随机效应模型进行meta分析。结果:我们纳入了101项研究(71%为横断面研究,11%为病例对照研究,13%为前瞻性研究,5%为可选研究),包括22项高质量研究,55项中等质量研究和24项低质量研究。荟萃分析显示相关但统计学无意义的协会的倦怠和VE症状较高的事件(优势比1.53[或]=[0.82,2.87],我²= 0%)和普遍大都会(或= 1.28[0.99,1.64],我²= 85%),事件肥胖(或= 1.88[0.81,4.36],我²= 0%)、腰臀比(标准平均差= 0.62 [-0.65,1.90],I2 = 95%),普遍高腰围(或= 1.14[0.80,1.62],我²= 28%),高甘油三酯(或= 1.49[0.82,2.71],我²= 40%),高血压患病率明显增高(OR = 1.63 [1.44, 1.84], I2 = 51%)。我们没有发现与其余MetS指标有临床相关性。结论:职业倦怠和VE症状可能与较高的MetS发生率相关,但无统计学意义。由于大多数研究采用的是横断面设计,使用的是未经调整的基线数据,而且在一些分析中存在很大的异质性,因此对这些结果的解释应谨慎。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
A randomized controlled trial: Evaluating whether a cognitive behavioral internet-delivered intervention targeting emotion regulation improves health-related quality of life in cancer survivors. 一项随机对照试验:评估以情绪调节为目标的认知行为互联网干预是否能改善癌症幸存者的健康相关生活质量。
IF 3.2 2区 心理学 Q1 PSYCHOLOGY Pub Date : 2025-10-01 Epub Date: 2025-04-10 DOI: 10.1037/hea0001497
Rebecca Wallace, Isabelle Smith, Daphne Day, Marliese Alexander, Karen L Weihs, Joshua F Wiley

Objective: Cancer survivors experience reduced overall health-related quality of life (HRQoL) compared to the general population. This research assesses and compares the efficacy of an emotion-focused (CanCopeMind [CM]) and lifestyle (CanCopeLifestyle [CL]) intervention to improve HRQoL among cancer survivors.

Method: This 8-week, internet-delivered, randomized controlled trial compared CM (n = 110) and CL (n = 114) on self-reported HRQoL (range -0.022 = indicating a state akin to dead to 1.0 representing perfect health) at baseline, postintervention, and 3-month follow-up. CM, adapted from the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, targeted core emotion regulation skills (understanding emotions, mindfulness, flexible thinking, and changing behaviors). CL, the active control, targeted healthy lifestyle domains (diet, exercise, relaxation, and sleep).

Results: HRQoL increased in both groups from baseline to postintervention (CM, p < .001, SMDmedian = 0.54; CL, p < .001, SMDmedian = 0.40), and these improvements were sustained at follow-up (CM, p < .001, SMDmedian = 0.52; CL, p = .005, SMDmedian = 0.33). The difference between each group was not significant at either postintervention (p = .095, SMDmedian = 0.19) or follow-up (p = .081, SMDmedian = 0.23). Subgroup analyses revealed no moderation by cancer stage, treatment type, months since treatment, cancer type or sex.

Conclusion: The findings indicate that an accessible, internet-delivered emotion-focused and lifestyle interventions hold promise for improving HRQoL among cancer survivors. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

目的:与普通人群相比,癌症幸存者的总体健康相关生活质量(HRQoL)降低。本研究评估并比较了以情绪为中心(CanCopeMind [CM])和生活方式(CanCopeLifestyle [CL])干预对改善癌症幸存者HRQoL的疗效。方法:这项为期8周的互联网随机对照试验比较了CM (n = 110)和CL (n = 114)在基线、干预后和3个月的随访中自我报告的HRQoL(范围从-0.022 =表示类似于死亡的状态到代表完美健康的1.0)。CM改编自《情绪障碍跨诊断治疗统一方案》,针对核心情绪调节技能(理解情绪、正念、灵活思维和改变行为)。CL,主动控制,目标健康的生活方式领域(饮食,运动,放松和睡眠)。结果:两组患者HRQoL均较干预后升高(CM, p < 0.001, SMDmedian = 0.54;CL, p < 0.001, SMDmedian = 0.40),这些改善在随访中持续(CM, p < 0.001, SMDmedian = 0.52;CL, p = 0.005, SMDmedian = 0.33)。干预后(p = 0.095, SMDmedian = 0.19)和随访(p = 0.081, SMDmedian = 0.23)两组间差异均无统计学意义。亚组分析显示,在癌症分期、治疗类型、治疗后数月、癌症类型或性别方面,没有任何缓和。结论:研究结果表明,一种可访问的、互联网传递的以情感为中心的生活方式干预有望改善癌症幸存者的HRQoL。(PsycInfo Database Record (c) 2025 APA,版权所有)。
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引用次数: 0
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Health Psychology
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