ON THE FRONT COVER: Artistic representation of an expansion microscopy image of human kidney tubular epithelium. Tissues were immunostained for primary cilia (acetylated α-tubulin, yellow), cell-cell junctions (E-cadherin, green/blue), and nuclei (DAPI, dark grey). The cover image is based on the article “Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures”.
Credit: Ewa Langner and Moe Mahjoub (Department of Medicine, Washington University, St Louis, MO).
封面：人肾小管上皮细胞扩张显微镜图像的艺术表现。组织上的初级纤毛（乙酰化 α-tubulin，黄色）、细胞-细胞连接（E-cadherin，绿色/蓝色）和细胞核（DAPI，深灰色）均经免疫染色。封面图片来源于文章 "Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures"（用于分析亚细胞结构的小鼠和人类肾脏超微结构扩展显微镜（U-ExM））。
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ON THE INNER BACK COVER: Cross section of retinal photoreceptors. Green: outer segments (wheat germ agglutinin); red: actin filaments in the inner segment and outer segment base (phalloidin); blue: nuclei.
Credit for Mohona Gupta and Gregory Pazour (Program of Molecular Medicine, University of Massachusetts, Chan Medical School).
{"title":"Inner Back Cover Image","authors":"","doi":"10.1002/cm.21959","DOIUrl":"https://doi.org/10.1002/cm.21959","url":null,"abstract":"<p>ON THE INNER BACK COVER: Cross section of retinal photoreceptors. Green: outer segments (wheat germ agglutinin); red: actin filaments in the inner segment and outer segment base (phalloidin); blue: nuclei.</p><p>Credit for Mohona Gupta and Gregory Pazour (Program of Molecular Medicine, University of Massachusetts, Chan Medical School).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"C3"},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21959","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ON THE BACK COVER: Waveforms predicted by a multifilament model of the axoneme for three different values of the elastic resistance to twisting, which may be attributed to torsional stiffness of radial spokes (increasing stiffness top to bottom).
Credit: Louis G. Woodhams and Philip V. Bayly (Washington University in St. Louis, McKelvey School of Engineering).
{"title":"Back Cover Image","authors":"","doi":"10.1002/cm.21960","DOIUrl":"https://doi.org/10.1002/cm.21960","url":null,"abstract":"<p>ON THE BACK COVER: Waveforms predicted by a multifilament model of the axoneme for three different values of the elastic resistance to twisting, which may be attributed to torsional stiffness of radial spokes (increasing stiffness top to bottom).</p><p>Credit: Louis G. Woodhams and Philip V. Bayly (Washington University in St. Louis, McKelvey School of Engineering).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"C4"},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21960","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ON THE INNER FRONT COVER: Expansion microscopy image of a mouse kidney tubular epithelium. Tissues were immunostained for primary cilia (acetylated α-tubulin, green), cell-cell junctions (E-cadherin, purple), cytoplasmic microtubules (α-tubulin, cyan), and nuclei (DAPI, orange). The cover image is based on the article “Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures”.
Credit: Ewa Langner (Department of Medicine, Washington University, St Louis, MO).
封面内页：小鼠肾小管上皮细胞的膨胀显微镜图像。对组织进行免疫染色，以检测初级纤毛（乙酰化α-微管蛋白，绿色）、细胞-细胞连接（E-cadherin，紫色）、细胞质微管（α-微管蛋白，青色）和细胞核（DAPI，橙色）。封面图片来源于文章 "Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures"（用于分析亚细胞结构的小鼠和人类肾脏超微结构扩展显微镜（U-ExM））。
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{"title":"Picture of the Month by Giuliano Callaini","authors":"","doi":"10.1002/cm.21944","DOIUrl":"10.1002/cm.21944","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"699"},"PeriodicalIF":2.4,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Picture of the Month by Pongpratch Puapatanakul","authors":"","doi":"10.1002/cm.21945","DOIUrl":"10.1002/cm.21945","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"700"},"PeriodicalIF":2.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Picture of the Month by Ewa Langner","authors":"","doi":"10.1002/cm.21946","DOIUrl":"10.1002/cm.21946","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"701"},"PeriodicalIF":2.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Picture of the Month by Mohona Gupta","authors":"","doi":"10.1002/cm.21947","DOIUrl":"10.1002/cm.21947","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"702"},"PeriodicalIF":2.4,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ON THE BACK COVER: DA-Raf inhibits ERK activation, resulting in the suppression of collective cell migration and invasion of KRAS-mutant cancer cells. In human pancreatic carcinoma MIA PaCa-2 cells, phospho-ERK1/2 (magenta) is suppressed by the expression of EGFP-DA-Raf (green). EGFP-DA-Raf is concentrated on the plasma membrane.
Credit: Aoi Matsuda and Takeshi Endo (Chiba University, Japan)
{"title":"Back Cover Image","authors":"","doi":"10.1002/cm.21940","DOIUrl":"https://doi.org/10.1002/cm.21940","url":null,"abstract":"<p>ON THE BACK COVER: DA-Raf inhibits ERK activation, resulting in the suppression of collective cell migration and invasion of KRAS-mutant cancer cells. In human pancreatic carcinoma MIA PaCa-2 cells, phospho-ERK1/2 (magenta) is suppressed by the expression of EGFP-DA-Raf (green). EGFP-DA-Raf is concentrated on the plasma membrane.</p><p>Credit: Aoi Matsuda and Takeshi Endo (Chiba University, Japan)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 9-10","pages":"C4"},"PeriodicalIF":2.4,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21940","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ON THE INNER FRONT COVER: Actin filaments (green) terminating in focal adhesions stained for vinculin (red) in bovine aortic endothelial cells cultured on polydimethylsiloxane. Nuclei are stained using dapi (blue).
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