ON THE BACK COVER: The image shows that the FtsZ inhibitor, PC190723, disrupts Z-rings in Escherichia coli mutants lacking a crucial saltbridge interaction within the inhibitor's binding pocket on FtsZ.
Credit: Sakshi Poddar and Ramanujam Srinivasan (School of Biological Sciences, National Institute of Science Education and Research, India).
ON THE FRONT COVER: The image shows the assembly of Helicobacter pylori FtsZ-GFP (HpFtsZ-GFP) into spiral structures when expressed in fission yeast, Schizosaccharomyces pombe. Three-dimensional structured illumination microscopy (3D-SIM) was used to image the structures and maximum intensity projection images are shown.
Credit: Sakshi Poddar and Ramanujam Srinivasan (School of Biological Sciences, National Institute of Science Education and Research, India).
ON THE INNER BACK COVER: Immunolabeling of Myosin VI in apical processes of Sertoli cells that enclose hook shaped maturing spermatids in the rat. Actin filaments are stained in red, while antibodies to Myosin VI are labelled in green. The 𡀘bulbs𡀙 at the ends of linear tubulobulbar complexes, are labelled in blue.
Credit: Samuel Tretjakov (Life Sciences Institute and Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, B.C., Canada)
ON THE BACK COVER: Five-day old control mature myofibrils in a cultured skeletal muscle cell stained for Titin (Red), Myosin II (Magenta) and Actin (Green).
Credit: Jushuo Wang and Yingli Fan. Department of Cell and Developmental Biology (SUNY Upstate Medical University, Syracuse, NY, USA)
ON THE INNER FRONT COVER: Spheroids composed of MCF10A EGFP and Lifeact-RFP (Magenta) cells with Hoechst-stained nuclei (Blue).
Credit: Grace Cai (Applied Physics Program, University of Michigan, USA)
ON THE FRONT COVER: Immunolabeling of Myosin VI in apical processes of Sertoli cells that enclose hook shaped maturing spermatids in the rat. Actin filaments are stained in red, while antibodies to Myosin VI are labelled in green. The 𡀘bulbs𡀙 at the ends of linear tubulobulbar complexes, are labelled in blue.
Credit: Samuel Tretjakov (Life Sciences Institute and Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, B.C., Canada)
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