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Australian Prescriber最新文献

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Wither Australian Prescriber? 枯萎澳大利亚处方?
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.076
John Dowden
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引用次数: 0
Mecasermin for primary insulin-like growth factor-1 deficiency. Mecasermin治疗原发性胰岛素样生长因子-1缺乏。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.077
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引用次数: 0
Pemigatinib for cholangiocarcinoma. Pemigatinib治疗胆管癌。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.078
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引用次数: 0
Selinexor for multiple myeloma. Selinexor治疗多发性骨髓瘤。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.072
Exportin-1 is an essential nuclear exporter of many tumour suppressor proteins, growth regulator proteins and several classes of messenger RNAs, including those of oncogenic proteins. It is overexpressed in several cancers including multiple myeloma. Selinexor is a selective inhibitor of exportin-1. This inhibition leads to marked accumulation of the tumour suppressor proteins and growth regulator proteins in the nucleus and reduced expression of several oncoproteins, resulting in cell cycle arrest and apoptosis of cancer cells.
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引用次数: 0
Decitabine/cedazuridine for chronic myelomonocytic leukaemia, myelodysplastic syndromes. 地西他滨/cedazuridine治疗慢性髓单核细胞白血病,骨髓增生异常综合征。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.071
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引用次数: 0
Elasomeran/imelasomeran for prevention of COVID-19. 用于预防新冠肺炎的Elasomeran/imelasomeran。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.073
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引用次数: 0
Osteonecrosis of the jaw and denosumab. 颌骨骨坏死和地诺单抗。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.066
Alastair N Goss
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引用次数: 2
The end of NPS MedicineWise. NPS MedicineWise的终结。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.075
Deborah Rigby
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引用次数: 0
Diuretics in the management of chronic heart failure: when and how. 利尿剂在慢性心力衰竭治疗中的应用:时间和方式。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.069
Joseph S Magdy, James McVeigh, Praveen Indraratna

Heart failure is an increasingly prevalent condition resulting in recurrent hospitalisations and significant mortality and morbidity. The management of heart failure has evolved, and multiple drugs have an established mortality benefit in heart failure with reduced ejection fraction. Although the focus should be on ensuring that patients are treated with the maximum tolerated doses of these guideline-directed therapies, diuretics continue to play a key role in the management of clinical congestion in all forms of heart failure. Clinicians play a key role in heart failure management. Familiarity with the role of diuretics and their dosing and monitoring is critical.

心力衰竭是一种越来越普遍的疾病,导致反复住院和显著的死亡率和发病率。心力衰竭的治疗已经发生了变化,多种药物在降低射血分数的心力衰竭中具有确定的死亡率益处。尽管重点应放在确保患者接受指南指导的最大耐受剂量的治疗上,但利尿剂在各种形式心力衰竭的临床充血管理中仍然发挥着关键作用。临床医生在心力衰竭管理中起着关键作用。熟悉利尿剂的作用及其剂量和监测至关重要。
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引用次数: 0
Administration of medicines to children: a practical guide. 儿童用药:实用指南。
IF 2.7 Q2 PHARMACOLOGY & PHARMACY Pub Date : 2022-12-01 DOI: 10.18773/austprescr.2022.067
Lucinda Smith, Catherine Leggett, Corey Borg

Getting children to take medicines can be difficult. There is no 'one-size-fits-all' approach. When selecting medicines for children, it is important to consider the child's age, swallowing ability, ease of administration and accessibility of the product. Ask the child, parent or caregiver about their preference for formulations and flavours. There are different ways to alter the taste, aftertaste and mouth feel of medicines, which may help improve palatability. Pharmacists or medicines information services can assist with advice on suitable formulations or methods of administration.

让孩子们吃药是很困难的。没有“放之四海而皆准”的方法。在为儿童选择药物时,重要的是要考虑儿童的年龄、吞咽能力、给药的容易程度和产品的可及性。询问孩子、父母或照顾者他们对配方和口味的偏好。有不同的方法可以改变药物的味道、余味和口感,这可能有助于提高适口性。药剂师或药物信息服务可协助提供适当的配方或给药方法的建议。
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引用次数: 2
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Australian Prescriber
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