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Factors of postoperative recurrent laryngeal nerve paralysis and recovery of vocal cord movement in thyroid surgery 甲状腺手术术后喉返神经麻痹和声带运动恢复的因素
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-29 DOI: 10.1016/j.anl.2024.08.006
Kazufumi Obata, Makoto Kurose, Akito Kakiuchi, Kenichi Takano

Objective

Postoperative recurrent laryngeal nerve paralysis is one of the complications of thyroid surgery, and the prevention and management of paralysis is an important issue for surgeons. In this study, in order to gain further understanding of recurrent laryngeal nerve paralysis after thyroid surgery, we analyzed and examined the usefulness of nerve stimulators for recurrent laryngeal nerve paralysis and the factors that may cause recurrent laryngeal nerve paralysis. Furthermore, in cases where transient recurrent laryngeal nerve paralysis occurred, we analyzed and examined the timing of improvement in vocal cord movement for each intraoperative finding and intraoperative operation that caused the paralysis.

Methods

At the Department of Otorhinolaryngology Head and Neck Surgery, Sapporo Medical University Hospital, between January 2012 and December 2021, the subjects were 543 thyroid surgery cases (692 nerves) without preoperative paralysis or cancer nerve invasion performed. The relationship between postoperative transient and permanent paralysis of the recurrent laryngeal nerve was evaluated using univariate and multivariate analysis. The factors evaluated were gender, age, BMI, total thyroidectomy, benignity, malignancy, Graves’ disease, using IIONM (intermittent intraoperative nerve monitoring), using CIONM (continuous intraoperative nerve monitoring), malignant tumor T3b or higher, with lateral neck dissection, and years of experience of the surgeon. Furthermore, by targeting 87 nerves with transient paralysis, surgical operations were divided into three groups: minor injury, major injury, and adhesion, and their relationship with the timing of postoperative vocal fold movement improvement was evaluated.

Results

Permanent paralysis of the recurrent laryngeal nerve occurred in 12 nerves (1.7 %), and transient paralysis occurred in 100 nerves (14.5 %). Univariate analysis showed no association with each factor, but multivariate analysis showed that transient paralysis was significantly lower in men and in patients using IIONM. The improvement time for vocal cord paralysis was 2.8 months in the minor injury group, 4.5 months in the major injury group, and 3.2 months in the adhesion group, indicating a statistically significant difference between the minor injury group and the major injury group.

Conclusion

This study suggests that the use of IIONM and gentle manipulation of women may prevent recurrent laryngeal nerve paralysis during thyroid surgery. In addition, understanding the period of nerve recovery for each operation for postoperative transient recurrent laryngeal nerve paralysis may contribute to patient explanations and determining the timing of therapeutic intervention for speech improvement surgery.

目的 术后喉返神经麻痹是甲状腺手术的并发症之一,如何预防和处理麻痹是外科医生面临的重要问题。在本研究中,为了进一步了解甲状腺手术后喉返神经麻痹的情况,我们分析并研究了神经刺激器对喉返神经麻痹的作用以及可能导致喉返神经麻痹的因素。方法:札幌医科大学附属医院耳鼻咽喉头颈外科在2012年1月至2021年12月期间,以543例(692条神经)术前未发生麻痹或癌神经侵犯的甲状腺手术病例为研究对象。通过单变量和多变量分析评估了喉返神经术后一过性麻痹和永久性麻痹之间的关系。评估因素包括性别、年龄、体重指数、甲状腺全切除术、良性肿瘤、恶性肿瘤、巴塞杜氏病、使用 IIONM(间歇性术中神经监测)、使用 CIONM(连续性术中神经监测)、T3b 或更高的恶性肿瘤、侧颈部切除术以及外科医生的经验年限。此外,针对 87 条出现一过性麻痹的神经,将手术操作分为三组:轻微损伤组、严重损伤组和粘连组,并评估了它们与术后声带运动改善时间的关系。结果12 条神经(1.7%)出现喉返神经永久性麻痹,100 条神经(14.5%)出现一过性麻痹。单变量分析表明,各因素之间没有关联,但多变量分析表明,男性和使用 IIONM 的患者发生一过性麻痹的比例明显较低。轻伤组声带麻痹的改善时间为 2.8 个月,重伤组为 4.5 个月,粘连组为 3.2 个月,表明轻伤组和重伤组之间存在显著的统计学差异。结论这项研究表明,使用 IIONM 和对女性的轻柔操作可预防甲状腺手术中的喉返神经麻痹。此外,了解每种手术对术后一过性喉返神经麻痹的神经恢复期,有助于对患者进行解释,并确定语言改善手术的治疗干预时机。
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引用次数: 0
Effect of background noise and memory load on listening effort of young adults with and without hearing loss 背景噪音和记忆负担对有听力损失和无听力损失的年轻人听力的影响
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-27 DOI: 10.1016/j.anl.2024.08.005
Kumiko Nishida , Chie Obuchi , Masae Shiroma , Hidehiko Okamoto , Yoshihiro Noguchi

Objective

People with hearing loss often encounter difficulties in hearing under adverse conditions, such as listening in the presence of noise. Listening effort is an indicator used to assess listening difficulties in daily life. Although many studies on listening effort have been conducted in recent years, there is a notable gap in the exploration of how task load influences listening effort in young adults. This study compared the effects of background noise and memory load on task performance and subjective listening effort in young adults with and without hearing loss.

Methods

The study included a group of 8 adults with hearing loss (mean age: 24.1 ± 6.0 years) and a group of 16 individuals with normal hearing (mean age: 27.9 ± 4.9 years). A number memorizing task was conducted, involving two types of auditory digits (either three or seven digits) presented under multi-talker babble noise conditions of signal-to-noise ratio of −5 dB [SN −5 dB] or SN +5 dB. Participants determined whether the number presented in the encoding interval matched the one presented in the retrieval interval. Subsequently, they were asked to complete a questionnaire using a Visual Analog Scale (VAS) to assess their subjective listening effort. Percentage of correct responses, reaction times, and VAS ratings were compared between adults with and without hearing loss.

Results

Our results showed significant differences between the two groups in the percentage of correct responses and the reaction time under the SN −5 dB conditions, regardless of the memory load. Under the SN +5 dB conditions, a significant difference was found only in the percentage of correct responses for seven digits. In the normal hearing group, the percentage of correct responses and VAS ratings tended to decrease as the memory load increased, even under the same noise condition. Conversely, in the hearing loss group, a consistent trend could not be identified in the effects of noise and memory load on the percentage of correct responses and VAS ratings.

Conclusion

These results suggest that in conditions of high noise load, young adults with hearing loss show a higher tendency for listening effort to be affected by other loads. We confirmed that for some participants with hearing loss, the task exceeded a certain level of difficulty in the SN −5 dB and seven digits condition, leading to a change in their motivation and strategy used. Future research should examine ways to control for participants’ motivations.

目标听力损失患者经常会在不利条件下遇到听力困难,例如在噪音环境中聆听。听力努力是用于评估日常生活中听力困难的一项指标。虽然近年来对听力努力程度进行了许多研究,但在探索任务负荷如何影响青壮年听力努力程度方面还存在明显差距。本研究比较了背景噪声和记忆负担对有听力损失和无听力损失的年轻人的任务表现和主观听力努力程度的影响。方法 本研究包括一组 8 名有听力损失的成年人(平均年龄:24.1 ± 6.0 岁)和一组 16 名听力正常者(平均年龄:27.9 ± 4.9 岁)。在信噪比为 -5 dB [SN -5 dB] 或 SN +5 dB 的多语种咿呀噪音条件下,进行了一项数字记忆任务,涉及两种类型的听觉数字(三个或七个数字)。被试判断编码间隔中出现的数字是否与检索间隔中出现的数字一致。随后,他们被要求使用视觉模拟量表(VAS)填写一份问卷,以评估他们的主观听力努力程度。结果表明,在 SN -5 dB 条件下,无论记忆负荷如何,两组人的正确反应百分比和反应时间都存在显著差异。在 SN +5 dB 条件下,只有七个数字的正确反应百分比存在显著差异。在听力正常组中,即使在相同的噪声条件下,随着记忆负荷的增加,正确反应的百分比和 VAS 评分也呈下降趋势。相反,在听力损失组中,噪声和记忆负荷对正确回答百分比和 VAS 评分的影响没有一致的趋势。我们证实,对于一些听力损失的参与者来说,在 SN -5 dB 和七位数条件下,任务的难度超过了一定水平,从而导致他们的动机和策略发生变化。未来的研究应该研究如何控制参与者的动机。
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引用次数: 0
Relationship between sleep position and otitis media in infants: The Japan environment and children's study 睡眠姿势与婴儿中耳炎的关系:日本环境与儿童研究
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-24 DOI: 10.1016/j.anl.2024.08.001
Daisuke Kikuchi , Mitsuyoshi Imaizumi , Tsuyoshi Murata , Akiko Sato , Yuka Ogata , Kosei Shinoki , Hidekazu Nishigori , Keiya Fujimori , Mitsuaki Hosoya , Seiji Yasumura , Koichi Hashimoto , Shigeyuki Murono

Objective

Otitis media is a disease that commonly occurs in infants. Various risk factors have been reported. Sleep position has been reported to be associated with various diseases. There is no report on the relationship between otitis media and sleep position. We examined the incidence of otitis media and sleep position in infants.

Methods

We used data from the Japan Environment Children's Study. We used multivariate logistic analysis to examine the relationship between sleep position and the incidence of otitis media in infants aged up to 6 months. In addition, we conducted a stratified analysis based on whether the child was able to turn over in bed at 6 months of age.

Results

The study population comprised 85,731 participants. The incidence of otitis media by sleep position was significantly higher when the infant was in the prone position compared to any other position (adjusted odds ratio, 1.206; 95 %CI, 1.038–1.401). Stratified analysis of turning showed that otitis media was more common in the prone position in all groups.

Conclusion

In the current study, infants aged 6 months or younger who slept in the prone position were more likely to have otitis media. Sleep position interview and guidance on changing sleep position may be useful for the prevention of otitis media.

目的中耳炎是一种常见于婴儿的疾病。有报告称,中耳炎存在多种风险因素。据报道,睡眠姿势与多种疾病有关。目前还没有关于中耳炎与睡眠姿势之间关系的报告。我们对婴儿中耳炎的发病率和睡眠姿势进行了研究。我们采用多变量逻辑分析法研究了睡眠姿势与 6 个月以下婴儿中耳炎发病率之间的关系。此外,我们还根据婴儿 6 个月大时是否能在床上翻身进行了分层分析。与其他任何姿势相比,俯卧姿势的婴儿中耳炎发病率明显更高(调整后的几率比为 1.206;95 %CI 为 1.038-1.401)。结论 在当前的研究中,6 个月或更小的婴儿采用俯卧姿势睡觉更容易患中耳炎。睡眠姿势访谈和改变睡眠姿势的指导可能有助于预防中耳炎。
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引用次数: 0
Endoscopic Transpterygoid Repair of Sphenoid Sinus Meningocele: A Comprehensive Case Report and Literature Review 内窥镜经蝶窦修复蝶窦脑膜囊肿:综合病例报告和文献综述
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-19 DOI: 10.1016/j.anl.2024.08.003
Aiko Shimizu , Seiichiro Makihara , Ryoji Imoto , Koji Hirashita , Mizuo Ando

We report a challenging and uncommon case involving a 53-year-old Japanese man with cerebrospinal fluid (CSF) leakage caused by a meningocele in the lateral recess of the sphenoid sinus. Our innovative treatment approach involved a combination of transpterygoid and endoscopic modified medial maxillectomy techniques, with special emphasis on the preservation of the sphenopalatine artery. This strategic preservation was pivotal to the successful use of the ipsilateral nasoseptal flap for reconstruction, which played a crucial role in the prevention of postoperative CSF leakage. Otolaryngologists and neurosurgeons collaborated to perform the bath-plugging technique; effective collaboration was instrumental to the success of the procedure. This report highlights significant advancement from conventional frontal craniotomy to a more sophisticated endoscopic technique, shows the importance of meticulous surgical planning and execution, emphasizes careful preservation of critical anatomical structures during complex neurosurgical and otolaryngological procedures, and underscores the evolving landscape of surgical approaches for managing complex medical conditions.

我们报告了一例极具挑战性的罕见病例,患者是一名 53 岁的日本男子,其脑脊液(CSF)漏是由蝶窦外侧凹的脑膜囊引起的。我们的创新治疗方法是结合经蝶窦切除术和内窥镜改良上颌骨内侧切除术,特别强调保留蝶窦动脉。这种战略性的保留对于成功使用同侧鼻隔皮瓣进行重建至关重要,而鼻隔皮瓣在防止术后 CSF 渗漏方面发挥了关键作用。耳鼻喉科医生和神经外科医生合作实施了浴插技术;有效的合作对手术的成功至关重要。本报告强调了从传统的额部开颅手术到更复杂的内窥镜技术的重大进步,显示了缜密的手术计划和执行的重要性,强调了在复杂的神经外科和耳鼻喉科手术中小心保护关键解剖结构的重要性,并强调了管理复杂病症的手术方法的不断发展。
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引用次数: 0
Anteriorly tilted CT to visualize the anterior wall of the sphenoid sinus 前倾 CT 观察蝶窦前壁
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-14 DOI: 10.1016/j.anl.2024.07.008
Tomotaka Hemmi , Kazuhiro Nomura , Mitsuru Sugawara , Ryoukichi Ikeda

Objective

To elucidate the effectiveness of a 30-degree anteriorly tilted coronal CT in visualizing the anterior wall of the sphenoid sinus.

Methods

Medical records and CTs of patients who underwent septoplasty, inferior turbinectomy, or endoscopic sinus surgery were reviewed. We evaluated the visibility of the anterior wall of the sphenoid sinus on conventional coronal CT scans and categorized its orientation. We then created anteriorly tilted coronal CT images to evaluate its improved visibility.

Results

A total of 129 patients were evaluated. While conventional coronal CT scans fully visualized the anterior wall of the sphenoid sinus in cases with an Onodi cell, 17.7% remained unidentified when the Onodi cell was absent. However, anteriorly tilted coronal CT scans consistently identified the anterior wall regardless of the presence of an Onodi cell.

Conclusion

Our study highlights the effectiveness of anteriorly tilted coronal CT scans in consistently visualizing the anterior wall of the sphenoid sinus, regardless of the presence of an Onodi cell. It is possible that some other structures may become less identifiable on anteriorly tilted coronal CT.

方法回顾了接受鼻中隔成形术、下鼻甲切除术或内窥镜鼻窦手术患者的病历和 CT。我们在常规冠状 CT 扫描中评估了蝶窦前壁的可见度,并对其方向进行了分类。然后,我们制作了前倾的冠状 CT 图像,以评估其可见度的改善情况。在有奥诺迪细胞的病例中,常规冠状 CT 扫描可完全显示蝶窦前壁,而在没有奥诺迪细胞的病例中,17.7% 的病例仍无法识别。结论:我们的研究强调了前倾冠状 CT 扫描在持续显示蝶窦前壁方面的有效性,无论是否存在奥诺迪细胞。在前倾冠状 CT 扫描中,其他一些结构的可辨认性可能会降低。
{"title":"Anteriorly tilted CT to visualize the anterior wall of the sphenoid sinus","authors":"Tomotaka Hemmi ,&nbsp;Kazuhiro Nomura ,&nbsp;Mitsuru Sugawara ,&nbsp;Ryoukichi Ikeda","doi":"10.1016/j.anl.2024.07.008","DOIUrl":"10.1016/j.anl.2024.07.008","url":null,"abstract":"<div><h3>Objective</h3><p>To elucidate the effectiveness of a 30-degree anteriorly tilted coronal CT in visualizing the anterior wall of the sphenoid sinus.</p></div><div><h3>Methods</h3><p>Medical records and CTs of patients who underwent septoplasty, inferior turbinectomy, or endoscopic sinus surgery were reviewed. We evaluated the visibility of the anterior wall of the sphenoid sinus on conventional coronal CT scans and categorized its orientation. We then created anteriorly tilted coronal CT images to evaluate its improved visibility.</p></div><div><h3>Results</h3><p>A total of 129 patients were evaluated. While conventional coronal CT scans fully visualized the anterior wall of the sphenoid sinus in cases with an Onodi cell, 17.7% remained unidentified when the Onodi cell was absent. However, anteriorly tilted coronal CT scans consistently identified the anterior wall regardless of the presence of an Onodi cell.</p></div><div><h3>Conclusion</h3><p>Our study highlights the effectiveness of anteriorly tilted coronal CT scans in consistently visualizing the anterior wall of the sphenoid sinus, regardless of the presence of an Onodi cell. It is possible that some other structures may become less identifiable on anteriorly tilted coronal CT.</p></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"51 5","pages":"Pages 871-874"},"PeriodicalIF":1.6,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141985215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of dexmedetomidine on postoperative adenotonsillectomy oral intake and dehydration 右美托咪定对腺样体切除术后口腔摄入量和脱水的影响
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-08 DOI: 10.1016/j.anl.2024.07.009
Wooyoung Jang , Cynthia Schwartz , Zheyar Seyan , Isaiah Garcia , Stephanie Stroever , Abdul Awal , Winslo K. Idicula

Objective

To determine if perioperative administration of dexmedetomidine affects postoperative fluid intake in tonsillectomy patients.

Methods

A retrospective chart review was performed at University Medical Center, Texas Tech Health Science Center, Lubbock, Texas. The study identified 534 patients within the last five years who met the criteria. Common indications for the surgeries included recurrent tonsillitis, obstructive sleep apnea, and sleep disordered breathing. Patients with concurrent peritonsillar abscess drainage, microlaryngoscopy, bronchoscopy, supraglottoplasty, and other procedures that may impact fluid intake were excluded. The relationship between dexmedetomidine and fluid intake was evaluated using bivariate analysis as well as multivariable regression to account for possible confounders such as age, concurrent medication, surgery type, and method of surgery using STATA statistical software, version 17.0 (StataCorp LLC, College Station, TX).

Results

Administration of dexmedetomidine did not significantly impact the amount of fluid intake, fluid intake per kilogram per hour, or average postoperative pain levels in patients who underwent tonsillectomy or adenotonsillectomy in the bivariate analysis (p = 0.217, 0.489, 0.512 respectively) and multiple regression model (p = 0.156, 0.802, 0.795)

Conclusion

Dexmedetomidine does not negatively influence postoperative fluid intake levels in patients and should continue to be utilized in appropriately selected patients experiencing anxiety or agitation prior to surgery.

目的确定围手术期使用右美托咪定是否会影响扁桃体切除术患者的术后液体摄入量:德克萨斯州卢伯克市德克萨斯技术健康科学中心大学医学中心进行了一项回顾性病历审查。研究确定了过去五年中符合标准的 534 名患者。手术的常见适应症包括复发性扁桃体炎、阻塞性睡眠呼吸暂停和睡眠呼吸紊乱。排除了同时接受扁桃体周围脓肿引流术、显微喉镜检查、支气管镜检查、声门上成形术和其他可能影响液体摄入的手术的患者。使用STATA统计软件17.0版(StataCorp LLC, College Station, TX)进行双变量分析和多变量回归,以考虑年龄、并发症、手术类型和手术方法等可能的混杂因素,评估右美托咪定与液体摄入量之间的关系:结果:在双变量分析(P = 0.217、0.489、0.512)和多元回归分析中,右美托咪定对扁桃体切除术或腺扁桃体切除术患者的液体摄入量、每小时每公斤液体摄入量或术后平均疼痛水平没有明显影响。512)和多元回归模型(p = 0.156,0.802,0.795)结论:右美托咪定不会对患者术后液体摄入水平产生负面影响,应继续用于经适当选择的术前出现焦虑或躁动的患者。
{"title":"Effect of dexmedetomidine on postoperative adenotonsillectomy oral intake and dehydration","authors":"Wooyoung Jang ,&nbsp;Cynthia Schwartz ,&nbsp;Zheyar Seyan ,&nbsp;Isaiah Garcia ,&nbsp;Stephanie Stroever ,&nbsp;Abdul Awal ,&nbsp;Winslo K. Idicula","doi":"10.1016/j.anl.2024.07.009","DOIUrl":"10.1016/j.anl.2024.07.009","url":null,"abstract":"<div><h3>Objective</h3><p>To determine if perioperative administration of dexmedetomidine affects postoperative fluid intake in tonsillectomy patients.</p></div><div><h3>Methods</h3><p>A retrospective chart review was performed at University Medical Center, Texas Tech Health Science Center, Lubbock, Texas. The study identified 534 patients within the last five years who met the criteria. Common indications for the surgeries included recurrent tonsillitis, obstructive sleep apnea, and sleep disordered breathing. Patients with concurrent peritonsillar abscess drainage, microlaryngoscopy, bronchoscopy, supraglottoplasty, and other procedures that may impact fluid intake were excluded. The relationship between dexmedetomidine and fluid intake was evaluated using bivariate analysis as well as multivariable regression to account for possible confounders such as age, concurrent medication, surgery type, and method of surgery using STATA statistical software, version 17.0 (StataCorp LLC, College Station, TX).</p></div><div><h3>Results</h3><p>Administration of dexmedetomidine did not significantly impact the amount of fluid intake, fluid intake per kilogram per hour, or average postoperative pain levels in patients who underwent tonsillectomy or adenotonsillectomy in the bivariate analysis (<em>p</em> = 0.217, 0.489, 0.512 respectively) and multiple regression model (<em>p</em> = 0.156, 0.802, 0.795)</p></div><div><h3>Conclusion</h3><p>Dexmedetomidine does not negatively influence postoperative fluid intake levels in patients and should continue to be utilized in appropriately selected patients experiencing anxiety or agitation prior to surgery.</p></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"51 5","pages":"Pages 866-870"},"PeriodicalIF":1.6,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Narrow-band imaging to enhance intraneural dissection in head and neck schwannoma surgery: a quantitative evaluation 窄带成像增强头颈部分裂瘤手术中的硬膜内切除术:定量评估。
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-06 DOI: 10.1016/j.anl.2024.07.004
Keisuke Yamamoto, Makoto Kurose, Akito Kakiuchi, Kazufumi Obata, Tsuyoshi Okuni, Atsushi Kondo, Kenichi Takano

Objective

The objective of this study was to assess the utility of narrow-band imaging (NBI) for improving intraneural dissection during gross total resection of head and neck schwannoma. Specifically, we aimed to quantitatively evaluate whether NBI can enhance the identification of pseudocapsule and true capsule within the tumor.

Methods

Nine schwannoma surgery cases conducted between February 2018 and October 2022 were retrospectively analyzed. The surgical procedures followed established principles with a specific focus on utilizing NBI to distinguish between the pseudocapsule and true capsule. Intraneural dissection was performed by searching for a tumor surface with a fascicle-free window, followed by longitudinal incision of the pseudocapsule. NBI was used to distinguish between the pseudocapsule and true capsule. Surgical views were captured under both white light (WL) illumination and NBI for further analysis. The brightness and contrast of the pseudocapsule and true capsule were quantitatively measured using ImageJ and were compared.

Results

Under NBI, the pseudocapsule consistently appeared greenish-gray, whereas the true capsule exhibited a white appearance. Quantitative analysis revealed a statistically significant difference (p < 0.0001) in brightness between the pseudocapsule (mean grayscale value 52.1, 95%CI; 46.4–75.3) and true tumor capsule (mean grayscale value 120.8, 95%CI; 155.7–109.0) under NBI. Conversely, there was no statistically significant difference in the brightness of these structures under WL (p = 0.2067). NBI also showed significantly higher contrast between the two structures than did WL (contrast 73.6, 95%CI; 53.1–89.5 vs. 30.9, 95%CI; 1.0–47.5, p = 0.0034). Further spectral analysis revealed that the most substantial difference in brightness between the pseudocapsule and the true tumor capsule was observed in the red spectrum, with a difference in brightness of −0.6 (95%CI; −16.8–14.8) under WL and 83.5 (95%CI; 50.3–100.0) under NBI (p < 0.0001).

Conclusion

NBI proved to be a valuable tool for enhancing the identification of pseudocapsule and true capsule during intraneural dissection in head and neck schwannoma surgery. The improved contrast and membrane visibility offered by NBI might have the potential to reduce postoperative neurological deficits and improve surgical outcomes. Further research is warranted to validate our findings and explore the broader applications of NBI in schwannoma surgery.

研究目的本研究的目的是评估窄带成像(NBI)在头颈部裂隙瘤全切术中改善硬膜内解剖的实用性。具体而言,我们旨在定量评估窄带成像是否能增强对肿瘤内假包囊和真包囊的识别:回顾性分析了 2018 年 2 月至 2022 年 10 月间进行的 9 例分裂瘤手术。手术过程遵循既定原则,重点利用 NBI 区分假囊和真囊。通过寻找肿瘤表面的无筋膜窗进行硬膜内剥离,然后纵向切开假囊。NBI 用于区分假囊和真囊。手术视图在白光(WL)照明和 NBI 下拍摄,以便进一步分析。使用 ImageJ 对假囊肿和真囊肿的亮度和对比度进行了定量测量和比较:结果:在 NBI 下,假胶囊始终呈现青灰色,而真胶囊则呈现白色。定量分析显示,在 NBI 下,假囊(平均灰度值 52.1,95%CI;46.4-75.3)和真瘤囊(平均灰度值 120.8,95%CI;155.7-109.0)的亮度差异有统计学意义(p < 0.0001)。相反,在 WL 下,这些结构的亮度差异没有统计学意义(p = 0.2067)。NBI 显示的两个结构之间的对比度也明显高于 WL(对比度 73.6,95%CI;53.1-89.5 vs. 30.9,95%CI;1.0-47.5,p = 0.0034)。进一步的光谱分析显示,假囊与真肿瘤囊之间最显著的亮度差异出现在红色光谱上,WL下的亮度差异为-0.6 (95%CI; -16.8-14.8),而NBI下的亮度差异为83.5 (95%CI; 50.3-100.0)(p < 0.0001):事实证明,在头颈部裂隙瘤手术的硬膜内剥离过程中,NBI是增强假包囊和真包囊识别能力的重要工具。NBI 可提高对比度和膜的可见度,有可能减少术后神经功能缺损并改善手术效果。为了验证我们的研究结果并探索 NBI 在分裂瘤手术中的更广泛应用,有必要开展进一步的研究。
{"title":"Narrow-band imaging to enhance intraneural dissection in head and neck schwannoma surgery: a quantitative evaluation","authors":"Keisuke Yamamoto,&nbsp;Makoto Kurose,&nbsp;Akito Kakiuchi,&nbsp;Kazufumi Obata,&nbsp;Tsuyoshi Okuni,&nbsp;Atsushi Kondo,&nbsp;Kenichi Takano","doi":"10.1016/j.anl.2024.07.004","DOIUrl":"10.1016/j.anl.2024.07.004","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of this study was to assess the utility of narrow-band imaging (NBI) for improving intraneural dissection during gross total resection of head and neck schwannoma. Specifically, we aimed to quantitatively evaluate whether NBI can enhance the identification of pseudocapsule and true capsule within the tumor.</p></div><div><h3>Methods</h3><p>Nine schwannoma surgery cases conducted between February 2018 and October 2022 were retrospectively analyzed. The surgical procedures followed established principles with a specific focus on utilizing NBI to distinguish between the pseudocapsule and true capsule. Intraneural dissection was performed by searching for a tumor surface with a fascicle-free window, followed by longitudinal incision of the pseudocapsule. NBI was used to distinguish between the pseudocapsule and true capsule. Surgical views were captured under both white light (WL) illumination and NBI for further analysis. The brightness and contrast of the pseudocapsule and true capsule were quantitatively measured using ImageJ and were compared.</p></div><div><h3>Results</h3><p>Under NBI, the pseudocapsule consistently appeared greenish-gray, whereas the true capsule exhibited a white appearance. Quantitative analysis revealed a statistically significant difference (<em>p</em> &lt; 0.0001) in brightness between the pseudocapsule (mean grayscale value 52.1, 95%CI; 46.4–75.3) and true tumor capsule (mean grayscale value 120.8, 95%CI; 155.7–109.0) under NBI. Conversely, there was no statistically significant difference in the brightness of these structures under WL (<em>p</em> = 0.2067). NBI also showed significantly higher contrast between the two structures than did WL (contrast 73.6, 95%CI; 53.1–89.5 vs. 30.9, 95%CI; 1.0–47.5, <em>p</em> = 0.0034). Further spectral analysis revealed that the most substantial difference in brightness between the pseudocapsule and the true tumor capsule was observed in the red spectrum, with a difference in brightness of −0.6 (95%CI; −16.8–14.8) under WL and 83.5 (95%CI; 50.3–100.0) under NBI (<em>p</em> &lt; 0.0001).</p></div><div><h3>Conclusion</h3><p>NBI proved to be a valuable tool for enhancing the identification of pseudocapsule and true capsule during intraneural dissection in head and neck schwannoma surgery. The improved contrast and membrane visibility offered by NBI might have the potential to reduce postoperative neurological deficits and improve surgical outcomes. Further research is warranted to validate our findings and explore the broader applications of NBI in schwannoma surgery.</p></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"51 5","pages":"Pages 859-865"},"PeriodicalIF":1.6,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sudden sensorineural hearing loss during the Covid-19 pandemic; experience of a tertiary referral center Covid-19 大流行期间的突发性感音神经性听力损失;一家三级转诊中心的经验。
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.anl.2024.07.006
Ozan Özdemir, Ramazan Çelik, Özgür Yiğit

Objective

This study aimed to highlight the differences in the clinical management and treatment of sudden sensorineural hearing loss (SSNHL) due to the impact of the Coronavirus Disease 2019 (COVID-19) pandemic.

Methods

This study compared patients diagnosed with SSNHL between March 2020 and March 2022, following the first reported case of COVID-19 in our country, with patients diagnosed between March 2018 and March 2020. The evaluation encompassed demographic characteristics, comorbidities, other ear-related complaints, hearing loss thresholds at each frequency, medical treatment administered, treatment duration, and post-treatment follow-up audiograms.

Results

The demographic characteristics and comorbidities of patients before and during the pandemic showed similar distribution. There was no significant difference in the duration from the onset of symptoms to hospital admission during the pandemic compared to the previous period. When evaluating the treatment responses of hospitalized and treated patients according to Siegel's criteria during the pandemic, a similar trend to the pre-pandemic period was observed. It was noted that the use of systemic steroids and hyperbaric oxygen therapy decreased during the pandemic period, while the use of antivirals increased.

Conclusions

In our study conducted as a reference center, we want to emphasize that no clear data indicating a relationship between COVID-19 infection and NHL. Also, we believe that COVID-19 infection does not affect the course and prognosis of SSNHL.

目的本研究旨在强调突发性感音神经性听力损失(SSNHL)的临床管理和治疗因 2019 年冠状病毒病(COVID-19)大流行的影响而存在的差异:本研究比较了在我国首次报告 COVID-19 病例后 2020 年 3 月至 2022 年 3 月期间确诊的 SSNHL 患者与 2018 年 3 月至 2020 年 3 月期间确诊的患者。评估内容包括人口统计学特征、合并症、其他耳部相关主诉、各频率听力损失阈值、所接受的治疗、治疗持续时间以及治疗后随访听力图:大流行前和大流行期间患者的人口统计学特征和合并症分布相似。与之前相比,大流行期间患者从发病到入院的持续时间没有明显差异。根据西格尔标准评估大流行期间住院和接受治疗的病人的治疗反应时,观察到与大流行前相似的趋势。我们注意到,在大流行期间,全身类固醇和高压氧疗法的使用减少了,而抗病毒药物的使用却增加了:在我们作为参考中心进行的研究中,我们要强调的是,没有明确的数据表明 COVID-19 感染与 NHL 之间存在关系。此外,我们认为 COVID-19 感染不会影响 SSNHL 的病程和预后。
{"title":"Sudden sensorineural hearing loss during the Covid-19 pandemic; experience of a tertiary referral center","authors":"Ozan Özdemir,&nbsp;Ramazan Çelik,&nbsp;Özgür Yiğit","doi":"10.1016/j.anl.2024.07.006","DOIUrl":"10.1016/j.anl.2024.07.006","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to highlight the differences in the clinical management and treatment of sudden sensorineural hearing loss (SSNHL) due to the impact of the Coronavirus Disease 2019 (COVID-19) pandemic.</p></div><div><h3>Methods</h3><p>This study compared patients diagnosed with SSNHL between March 2020 and March 2022, following the first reported case of COVID-19 in our country, with patients diagnosed between March 2018 and March 2020. The evaluation encompassed demographic characteristics, comorbidities, other ear-related complaints, hearing loss thresholds at each frequency, medical treatment administered, treatment duration, and post-treatment follow-up audiograms.</p></div><div><h3>Results</h3><p>The demographic characteristics and comorbidities of patients before and during the pandemic showed similar distribution. There was no significant difference in the duration from the onset of symptoms to hospital admission during the pandemic compared to the previous period. When evaluating the treatment responses of hospitalized and treated patients according to Siegel's criteria during the pandemic, a similar trend to the pre-pandemic period was observed. It was noted that the use of systemic steroids and hyperbaric oxygen therapy decreased during the pandemic period, while the use of antivirals increased.</p></div><div><h3>Conclusions</h3><p>In our study conducted as a reference center, we want to emphasize that no clear data indicating a relationship between COVID-19 infection and NHL. Also, we believe that COVID-19 infection does not affect the course and prognosis of SSNHL.</p></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"51 5","pages":"Pages 853-858"},"PeriodicalIF":1.6,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141891116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significant influence of prelingual deafness but less impact of elderly age at implantation on long-term psychoacoustic CI programming parameters 舌前耳聋对长期心理声学 CI 程序参数的影响很大,但植入时的高龄影响较小。
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-07-30 DOI: 10.1016/j.anl.2024.07.007
Hiroshi Yamazaki , Saburo Moroto , Tomoko Yamazaki , Rinko Tamaya , Naoko Fujii , Keizo Fujiwara , Norio Yamamoto , Yasushi Naito

Objective

This study aimed to elucidate the long-term impact of prelingual deafness and elderly age at cochlear implantation on cochlear implant (CI) programming parameters and CI thresholds

Methods

We retrospectively reviewed patients who underwent cochlear implantation less than 5 years (Prelingual group) and equal and more than 18 years in our institute. The latter group was further divided into Adult and Elderly groups according to whether the patient was younger or older than 65 at implantation. From 152, 69, and 55 patients in the Prelingual, Adult, and Elderly groups, 242, 92, and 58 ears were included. We compared CI thresholds and CI programming parameters, including impedances, T/C levels, and dynamic ranges for 8 years after implantation between the Prelingual, Adult, and Elderly groups.

Results

The Prelingual group showed consistently lower CI thresholds than the Adult and Elderly groups during the postoperative 2-8 years, but no difference was detected between the Elderly and Adult groups, except at the postoperative 4 years. The elderly group's CI thresholds did not deteriorate until postoperative 8 years. The Prelingual group showed consistently larger T/C levels (minimum/maximum current strength from CI), especially C levels, than the other two groups. At the same time, there was no significant difference between the Elderly and Adult groups except for smaller dynamic ranges in the Elderly group until postoperative 2 years. These results in the CI programming parameters might explain the lower CI thresholds in the Prelingual group than in the other groups. Focusing on CI maps 1 and 3 years after implantation, the strength of the T/C levels was similar for all channels in the Prelingual group, but the Adult and Elderly groups showed larger electrical stimuli in channels responsible for the middle frequencies than those for the lower or higher frequencies.

Conclusions

Our results suggest a significant influence of prelingual deafness but less impact of elderly age at implantation on long-term CI programming parameters and CI thresholds. The larger C levels and lower CI thresholds in the Prelingual group than in the Adult and Elderly groups implied that CI children with prelingual deafness tolerate and prefer larger CI stimuli, which may reflect the CI-dependent development of their auditory system before the critical period. No age-related reduction in hearing thresholds was observed in the Elderly group, probably because the CI compensates for age-related dysfunction of the peripheral auditory system.

研究目的本研究旨在阐明语前聋和老年人工耳蜗植入对人工耳蜗植入(CI)程序参数和 CI 阈值的长期影响 方法:我们回顾性地审查了在我院接受人工耳蜗植入术小于 5 年(语前组)和等于 18 年及以上的患者。根据患者植入时的年龄是小于还是大于 65 岁,我们又将后一组患者分为成人组和老年组。在舌前组、成人组和老年组的 152、69 和 55 名患者中,我们分别纳入了 242、92 和 58 耳。我们比较了舌前组、成人组和老年组植入 CI 8 年后的 CI 阈值和 CI 编程参数,包括阻抗、T/C 水平和动态范围:结果:在术后 2-8 年期间,舌前组的 CI 阈值一直低于成人组和老年组,但除术后 4 年外,老年组和成人组之间未发现任何差异。老年组的 CI 阈值直到术后 8 年才出现恶化。舌前组的 T/C 水平(CI 的最小/最大电流强度)一直高于其他两组,尤其是 C 水平。与此同时,除了老年组的动态范围较小之外,老年组和成人组之间没有明显差异,直到术后 2 年。CI 程序参数的这些结果可能解释了为什么舌前组的 CI 阈值低于其他组。从植入 1 年和 3 年后的 CI 地图来看,舌前组所有通道的 T/C 水平强度相似,但成人组和老年人组负责中频的通道比负责低频或高频的通道显示出更大的电刺激:我们的研究结果表明,舌前性耳聋对长期 CI 编程参数和 CI 阈值的影响很大,但植入时的老年性耳聋影响较小。与成人组和老年组相比,语前聋组的 C 水平较大,CI 门限较低,这意味着语前聋 CI 儿童能忍受并偏爱较大的 CI 刺激,这可能反映了他们的听觉系统在关键期之前的发展依赖于 CI。在老年组中没有观察到与年龄有关的听阈降低,这可能是因为 CI 补偿了与年龄有关的外周听觉系统功能障碍。
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引用次数: 0
Summary of Japanese clinical practice guidelines for Bell's palsy (idiopathic facial palsy) - 2023 update edited by the Japan Society of Facial Nerve Research 日本面神经研究学会编辑的日本贝尔麻痹(特发性面瘫)临床实践指南摘要 - 2023 年更新版。
IF 1.6 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-07-29 DOI: 10.1016/j.anl.2024.07.003
Takashi Fujiwara , Naohito Hato , Takashi Kasahara , Daichi Kasuya , Kenji Shida , Makito Tanabe , Haruki Nakano , Shin-Ichi Haginomori , Masashi Hamada , Ayato Hayashi , Yasushi Furuta , Ken Matsuda , Naohito Morishima , Takechiyo Yamada , Takashi Nakagawa

Objective

The “Summary of Japanese clinical practice guidelines for Bell's palsy (idiopathic facial palsy) - 2023 update edited by the Japan Society of Facial Nerve Research” aims to review the latest evidence regarding the treatment of Bell's palsy and to provide appropriate recommendations.

Method

Regarding the treatment of Bell's palsy, a guideline panel identified key clinical questions using an analytic PICO framework. The panel produced recommendations following the standards for trustworthy guidelines and the GRADE approach. The panel considered the balance of benefits, harm, and preferences when making recommendations.

Results

The panel identified nine key clinical questions: systemic (high/standard dose) corticosteroids, intratympanic corticosteroids, systemic antivirals, decompression surgery, acupuncture, physical therapy, botulinum toxin, and reanimation surgery.

Conclusion

These guidelines strongly recommend systemic standard-dose corticosteroids for the clinical management of Bell's palsy. Other treatments are weakly recommended due to insufficient evidence. The absolute risk reduction of each treatment differed according to the disease severity. Therefore, physicians and patients should decide on treatment based on the disease severity.

目的:日本面神经研究学会编辑的《日本贝尔氏麻痹(特发性面瘫)临床实践指南摘要--2023 年更新版》旨在回顾有关贝尔氏麻痹治疗的最新证据,并提供适当的建议:关于贝尔氏麻痹的治疗,指南小组采用 PICO 分析框架确定了关键的临床问题。专家组按照值得信赖的指南标准和 GRADE 方法提出了建议。专家小组在提出建议时考虑了效益、危害和偏好之间的平衡:专家组确定了九个关键的临床问题:全身性(高/标准剂量)皮质类固醇、耳内皮质类固醇、全身性抗病毒药物、减压手术、针灸、理疗、肉毒杆菌毒素和再植手术:这些指南强烈建议在贝尔氏麻痹的临床治疗中使用标准剂量的全身性皮质类固醇。由于证据不足,其他治疗方法被弱化。每种治疗方法降低风险的绝对值因疾病严重程度而异。因此,医生和患者应根据疾病的严重程度来决定治疗方法。
{"title":"Summary of Japanese clinical practice guidelines for Bell's palsy (idiopathic facial palsy) - 2023 update edited by the Japan Society of Facial Nerve Research","authors":"Takashi Fujiwara ,&nbsp;Naohito Hato ,&nbsp;Takashi Kasahara ,&nbsp;Daichi Kasuya ,&nbsp;Kenji Shida ,&nbsp;Makito Tanabe ,&nbsp;Haruki Nakano ,&nbsp;Shin-Ichi Haginomori ,&nbsp;Masashi Hamada ,&nbsp;Ayato Hayashi ,&nbsp;Yasushi Furuta ,&nbsp;Ken Matsuda ,&nbsp;Naohito Morishima ,&nbsp;Takechiyo Yamada ,&nbsp;Takashi Nakagawa","doi":"10.1016/j.anl.2024.07.003","DOIUrl":"10.1016/j.anl.2024.07.003","url":null,"abstract":"<div><h3>Objective</h3><p>The “Summary of Japanese clinical practice guidelines for Bell's palsy (idiopathic facial palsy) - 2023 update edited by the Japan Society of Facial Nerve Research” aims to review the latest evidence regarding the treatment of Bell's palsy and to provide appropriate recommendations.</p></div><div><h3>Method</h3><p>Regarding the treatment of Bell's palsy, a guideline panel identified key clinical questions using an analytic PICO framework. The panel produced recommendations following the standards for trustworthy guidelines and the GRADE approach. The panel considered the balance of benefits, harm, and preferences when making recommendations.</p></div><div><h3>Results</h3><p>The panel identified nine key clinical questions: systemic (high/standard dose) corticosteroids, intratympanic corticosteroids, systemic antivirals, decompression surgery, acupuncture, physical therapy, botulinum toxin, and reanimation surgery.</p></div><div><h3>Conclusion</h3><p>These guidelines strongly recommend systemic standard-dose corticosteroids for the clinical management of Bell's palsy. Other treatments are weakly recommended due to insufficient evidence. The absolute risk reduction of each treatment differed according to the disease severity. Therefore, physicians and patients should decide on treatment based on the disease severity.</p></div>","PeriodicalId":55627,"journal":{"name":"Auris Nasus Larynx","volume":"51 5","pages":"Pages 840-845"},"PeriodicalIF":1.6,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0385814624000804/pdfft?md5=8d59fd688292ce159c04661a89e7c5cd&pid=1-s2.0-S0385814624000804-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Auris Nasus Larynx
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