Lancet Public Health最新文献

{"title":"Natural history of alcohol-use disorders: not the end of the story","authors":"Tim Slade, Siobhan O'Dean","doi":"10.1016/s2468-2667(25)00255-5","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00255-5","url":null,"abstract":"","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"4 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145382794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between exposure to digital alcohol marketing and alcohol use: a systematic review and meta-analysis","authors":"Scott I Donaldson, Alex M Russell, Kathryn La Capria, Amanda DeJesus, Emily Wang, Jamil Fayad, Jon-Patrick Allem","doi":"10.1016/s2468-2667(25)00219-1","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00219-1","url":null,"abstract":"","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"25 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145382798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poverty and death in the wealthiest of nations","authors":"David U Himmelstein, Steffie Woolhandler","doi":"10.1016/s2468-2667(25)00252-x","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00252-x","url":null,"abstract":"","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"60 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145382801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The natural history of DSM-5 alcohol-use disorder from late adolescence to middle adulthood in Australia: a prospective cohort study","authors":"Jessica A Kerr, Hanafi Mohamad Husin, Janni Leung, S Ghazaleh Dashti, Louisa Degenhardt, Susan Ellul, Elizabeth A Spry, Susan M Sawyer, Gabrielle Campbell, Wayne D Hall, Tesfa Mekonen Yimer, Gary Chung Kai Chan, George C Patton, Craig A Olsson","doi":"10.1016/s2468-2667(25)00225-7","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00225-7","url":null,"abstract":"","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"115 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145382808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unsecured debt in early adulthood and premature mortality in adults in the USA: a longitudinal analysis of prospective national cohort data","authors":"Samuel L Swift, Zihan Chen, Calvin Colvin, Katrina Kezios, Sebastian Calonico, Adina Zeki Al Hazzouri","doi":"10.1016/s2468-2667(25)00226-9","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00226-9","url":null,"abstract":"","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"1 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145382813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A public health perspective on assisted dying and its different modalities","authors":"Paola Sillitti, Clément Meier, Solenne Blanc, Laura Jones, Claudia Gamondi","doi":"10.1016/s2468-2667(25)00245-2","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00245-2","url":null,"abstract":"","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"101 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145383803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health: a public health crisis unfolding","authors":"","doi":"10.1016/s2468-2667(25)00261-0","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00261-0","url":null,"abstract":"More than 1 billion people worldwide live with a mental health condition. One in seven young people. Despite these alarming numbers, the public health response is woefully inadequate. In the words of Dr Tedros, WHO Director General, “Mental health remains one of the most neglected areas of public health and health services delivery”. Indeed, the <span><span>WHO report</span><svg aria-label=\"Opens in new window\" focusable=\"false\" height=\"20\" viewbox=\"0 0 8 8\"><path d=\"M1.12949 2.1072V1H7V6.85795H5.89111V2.90281L0.784057 8L0 7.21635L5.11902 2.1072H1.12949Z\"></path></svg></span> <em>World Mental Health Today</em>, published in September, paints a sobering picture with rising incidence rates, persistent service gaps, and a glaring neglect of youth-specific mental health needs. The global prevalence of mental health disorders reached 13·6%; 0·9% higher than a decade ago. The 2023 Global Burden of Diseases, Injuries, and Risk Factors Study (<span><span>GBD</span><svg aria-label=\"Opens in new window\" focusable=\"false\" height=\"20\" viewbox=\"0 0 8 8\"><path d=\"M1.12949 2.1072V1H7V6.85795H5.89111V2.90281L0.784057 8L0 7.21635L5.11902 2.1072H1.12949Z\"></path></svg></span>) published on Oct 12 reported a staggering increase in the burden of mental disorders globally. The leading mental health burdens are depression and anxiety, with the peak now occurring in those aged 15–19 years—an increase driven mainly by depressive and anxiety disorders. Since 2010, anxiety disorders in this age group have risen by nearly 70%, and depression by about 30%. This trajectory should be a cause for concern.","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"19 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145396686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of bacterial antimicrobial resistance in the WHO Eastern Mediterranean Region 1990–2021: a cross-country systematic analysis with forecasts to 2050","authors":"","doi":"10.1016/s2468-2667(25)00201-4","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00201-4","url":null,"abstract":"&lt;h3&gt;Background&lt;/h3&gt;Antimicrobial resistance (AMR) is an urgent global crisis and one of the world's most complex challenges. Although there is increasing evidence of its impact on human mortality and morbidity, precise burden estimation has many challenges, and thus far has been elusive for the Eastern Mediterranean Region. Here, we present a comprehensive time-trend analysis of regional and country-level AMR burden estimates in the WHO Eastern Mediterranean Region (EMR), between 1990 and 2021, with forecasts up to 2050.&lt;h3&gt;Methods&lt;/h3&gt;We estimated deaths and disability-adjusted life-years (DALYs) attributable to and associated with AMR for 11 infectious syndromes, 22 bacterial pathogens, and 84 pathogen–drug combinations for the WHO EMR and each of its countries from 1990 to 2021. Data were obtained from mortality registries, surveillance systems, hospital records, systematic literature reviews, and other sources. We based our modelling approach on five broad components: the number of deaths in which infection had a role, the proportion of infectious deaths attributable to a given infectious syndrome, the proportion of infectious syndrome deaths attributable to a given pathogen, the percentage of a given pathogen resistant to an antimicrobial drug of interest, and the excess risk of mortality (or duration of an infection) associated with this resistance. These components were then used to estimate the disease burden by using two counterfactual scenarios: deaths and DALYs attributable to AMR (considering an alternative scenario where drug-resistant infections are replaced with susceptible infections), and deaths and DALYs associated with AMR (considering an alternative scenario where infections would not occur at all). Predictive statistical modelling was applied to generate estimates of AMR burden for each country. We also generated AMR burden forecasts up to 2050. We generated 95% uncertainty intervals (UIs) for the final estimates by taking the 2·5th and 97·5th percentiles across 500 draws through the multistage computational pipeline, and models were cross-validated for out-of-sample predictive validity.&lt;h3&gt;Findings&lt;/h3&gt;We estimated 380 000 deaths (95% UI 332 000–426 000) associated with bacterial AMR and 92 800 deaths (78 300–111 000) attributable to bacterial AMR in the EMR in 2021. In the past 31 years, there was considerable variation in AMR mortality trends across countries of the region and different age groups. Between 1990 and 2021, associated deaths among children younger than 5 years decreased by 50·0% (38·2–62·0), while those among adults aged 70 and older rose by over 85·7% (95% UI 57·0–115·7). Six pathogens were identified as the primary generators of burden: &lt;em&gt;Streptococcus pneumoniae, Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Acinetobacter baumannii&lt;/em&gt;, and &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt;. A substantial increase in the AMR burden due to &lt;em&gt;S aureus&lt;/em&gt; was observed between 1990 (28 200 deaths [21 600","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"38 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National roll-out of social prescribing in England's primary care system: a longitudinal observational study using Clinical Practice Research Datalink data","authors":"Feifei Bu, Alexandra Burton, Naomi Launders, Amy E Taylor, Alvin Richards-Belle, Stephanie Tierney, David Osborn, Daisy Fancourt","doi":"10.1016/s2468-2667(25)00217-8","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00217-8","url":null,"abstract":"<h3>Background</h3>Social prescribing is growing rapidly in England and across the world. However, it remains unclear who it is reaching and how effectively it is being implemented. This study aimed to assess longitudinal trends in social prescribing in England's primary care system, including growth trajectories and target alignment, sociodemographic profiles of referred patients, and predictors of service refusal over time.<h3>Methods</h3>This nationwide, longitudinal observational study analysed primary care records from 1·2 million patients from 1736 general practitioner (GP) practices in the Clinical Practice Research Datalink in England. We estimated social prescribing trends between 2019 and 2023 using growth curve modelling on social prescribing numbers at the practice level. Descriptive analyses were used to show changes in sociodemographic profiles of social prescribing patients over time. To assess sociodemographic disparities in service refusal (defined as having a medical code of social prescribing declined), we used multilevel logistic regression models stratified by year, accounting for nested data structure where patients were nested within practices.<h3>Findings</h3>As of the end of 2023, an estimated 9·4 million GP consultations in England have involved social prescribing codes, and 5·5 million consultations have specifically led to social prescribing referrals. In 2023 alone, an estimated 1·3 million patients were referred to social prescribing. 60% of patients offered social prescribing were female and 23% were from ethnic minority groups. Representation from patients living in more deprived areas increased from 23% to 42% between 2017 and 2023. Service refusal declined from 22% to 12% between 2019 and 2023. Age, sex, and ethnicity were associated with service refusal across multiple years. Notably, in 2023, all age groups had higher odds of refusal compared with the youngest age group. Female patients had 21% (95% CI 0·77–0·82) lower odds of refusal than males, and patients from White ethnic backgrounds had 32% (1·26–1·39) higher odds of refusal than ethnic minority patients.<h3>Interpretation</h3>Social prescribing has expanded rapidly in England, far exceeding initial targets of 900 000 patients by 2023–24, suggesting broad service acceptability. Progress is being made in reaching specific target groups, such as more deprived communities. However, there are still disparities in accessibility and uptake, calling for targeted strategies to address underlying inequalities.<h3>Funding</h3>MQ Transforming Mental Health, Rosetrees-Stoneygate Trust Fellowship, National Academy for Social Prescribing.","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"21 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145153669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is a Wellbeing Economy, and what might its impact be on population health?","authors":"Gerry McCartney, Milena Büchs, Martin Hensher, Micaela Mazzei","doi":"10.1016/s2468-2667(25)00192-6","DOIUrl":"https://doi.org/10.1016/s2468-2667(25)00192-6","url":null,"abstract":"The current polycrisis (intersecting and mutually-reinforcing crises that are impacting our ecological, social, and economic systems) has foregrounded the need to transform economies to put them in service of people and planet, rather than design them in pursuit of ever more economic growth. This approach, termed a Wellbeing Economy, is the subject of considerable policy interest and could have substantial impacts on population health if widely implemented. We discuss different interpretations of similar terms for economic systems and how these interpretations imply incremental reforms to the dominant capitalist model, or a radical break in economic design. We detail routes to a Wellbeing Economy and suggest that more radical approaches hold greater potential to address the polycrisis and protect population health. We summarise how the implementation of a Wellbeing Economy could be a commensurate response to the polycrisis that might also yield substantial benefits for population health.","PeriodicalId":56027,"journal":{"name":"Lancet Public Health","volume":"9 1","pages":""},"PeriodicalIF":50.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145116391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}