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Association between childhood adversity and use of the health, social, and justice systems in Denmark (DANLIFE): a nationwide cohort study 丹麦儿童逆境与卫生、社会和司法系统使用之间的关系(DANLIFE):一项全国性队列研究
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-13 DOI: 10.1016/s2468-2667(24)00242-1
Bertina Kreshpaj, Leonie K Elsenburg, Signe Hald Andersen, Tjeerd Rudmer De Vries, Karsten Thielen, Naja Hulvej Rod

Background

Childhood adversities can negatively affect health and social outcomes. We aimed to assess the association between adversity in childhood and use of public services in early adulthood across three systems: health, social welfare, and justice.

Methods

We used Danish nationwide registry data on individuals born between 1980 and 1991 and followed up between 1998 and 2021. We evaluated annual exposure to adversity during childhood (age 0–16 years) across three dimensions—material deprivation, loss or threat of loss within the family, and family dynamics—and used this to divide individuals into five trajectory groups: low adversity, early-life material deprivation, persistent material deprivation, loss or threat of loss, and high adversity. We defined high-intensity users of each public service system as those above the 90th percentile in terms of hospital visits (health system) and weeks of social welfare use (social welfare system), and whether or not they were convicted for a crime (justice system) during early adulthood (age 18–40 years). We analysed the proportion of high-intensity users of each public service system across the childhood adversity trajectory groups. Logistic regression was used to assess whether the risk of becoming a high-intensity user differed by trajectory group relative to the low-adversity group, with adjustment for sex, parental education, parental origin, and maternal age at time of birth.

Findings

Of the 567 035 individuals in the cohort, 273 616 (48·3%) were in the low-adversity group, 128 238 (22·6%) were in the early-life material deprivation group, 100 959 (17·8%) were in the persistent material deprivation group, 43 826 (7·7%) were in the loss or threat of loss group, and 20 396 (3·6%) were in the high-adversity group. Childhood adversity was associated with a markedly higher risk of belonging to the high-intensity user group across all three public service systems. Specifically, low proportions of the low-adversity group became high-intensity users of the health system (19 675 [7·2%]), social welfare system (13 681 [5·0%]), and justice system (38 198 [14·0%]). By comparison, those in the high-adversity group were significantly more likely to become high-intensity users of the health system (4685 [23·0%]; adjusted odds ratio 2·81 [95% CI 2·71–2·93]), social welfare system (8158 [40·0%]; 8·88 [8·50–9·27]), and justice system (8681 [42·6%]; 3·62 [3·50–3·75]).

Interpretation

There were long-term effects of childhood adversities across three public service systems, with an association of high-intensity users among individuals who experienced childhood adversity. Systemic inequalities already present in childhood need to be addressed, with prioritisation of equitable resource allocation for those most in need of assistance.

Funding

Rockwool Foundation.
童年逆境会对健康和社会结果产生负面影响。我们的目的是评估童年逆境与成年早期公共服务使用之间的关系,涉及三个系统:健康、社会福利和司法。方法:我们使用了1980年至1991年出生的丹麦全国登记数据,并在1998年至2021年期间进行了随访。我们评估了儿童时期(0-16岁)每年遭受逆境的三个维度——物质剥夺、家庭内部损失或损失威胁,以及家庭动态——并以此将个体分为五个轨迹组:低逆境、早期物质剥夺、持续物质剥夺、损失或损失威胁,以及高逆境。我们将每个公共服务系统的高强度用户定义为在成年早期(18-40岁)就诊次数(卫生系统)和社会福利使用周数(社会福利系统)以及他们是否被定罪(司法系统)方面高于90百分位数的用户。我们分析了每个公共服务系统的高强度用户在童年逆境轨迹组中的比例。在调整性别、父母受教育程度、父母出身和母亲出生年龄等因素后,采用Logistic回归评估不同轨迹组与低逆境组之间成为高强度使用者的风险是否存在差异。结果567 035人中,低逆境组273 616人(48.3%),早年物质剥夺组128 238人(22.6%),持续物质剥夺组100 959人(17.8%),损失或威胁损失组43 826人(7.7%),高逆境组20 396人(3.6%)。在所有三个公共服务系统中,童年逆境与属于高强度用户群体的风险明显较高相关。具体而言,低逆境群体成为卫生系统(19 675[7.2%])、社会福利系统(13 681[5.0%])和司法系统(38 198[14.0%])的高强度使用者的比例较低。相比之下,高逆境组的人更有可能成为卫生系统的高强度使用者(4685人[23.0%];调整优势比2.81 [95% CI 2.71 - 1.93]),社会福利制度(8158 [40.0%];8.88(8.50 - 9.27)),司法系统(8681 (42.6%));3·62[3·50-3·75])。在三个公共服务系统中,童年逆境存在长期影响,经历过童年逆境的个人中存在高强度使用者的关联。需要解决儿童时期已经存在的系统性不平等问题,优先为最需要援助的人公平分配资源。FundingRockwool基础。
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引用次数: 0
Inequities in access to assistive technology: a call for action 获取辅助技术方面的不公平现象:行动呼吁
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-12 DOI: 10.1016/s2468-2667(24)00270-6
Luc de Witte, Rosalie van der Vaart
Based on existing cross-sectional studies, case studies, and policy-related reports, experts in the field of assistive technology have long suspected that even in high-income countries such as England not everyone who could benefit from assistive technology has access to it, and that there are inequities in access. However, there was little concrete data on the extent of these gaps. Those data have been provided in the study by Danemayer and colleagues.1 Elegantly using longitudinal data from the English Longitudinal Study of Ageing, the authors show that in a population of 12 080 participants, 2480 (20·5%) had an unmet need for mobility assistive products at baseline and 5102 (42·2%) had an unmet need at least once during the follow-up period, which had a median duration of 4 years. The data further revealed that there are important inequities in access: women, older adults, and people with low education levels, less wealth, or disabilities have higher chances of transitioning from no need to unmet need, with women additionally being less likely than men to transition from unmet need to use. This study is important because it not only provides directions for further research, but it also particularly underscores the need for improving policy and practice. These findings align closely with those from the large, global cross-sectional study into assistive technology needs and access, published by WHO and UNICEF in their Global Report on Assistive Technology.2 In that study, it was estimated that in countries with a very high human development index a median of 20·7% (range 16·5–59·8) of people with a need for assistive technology do not have access to it.
根据现有的横断面研究、案例研究和政策相关报告,辅助技术领域的专家长期以来一直怀疑,即使是在英国这样的高收入国家,也并非每个人都能从辅助技术中受益,而且在获得辅助技术方面存在不公平现象。然而,有关这些差距程度的具体数据却很少。作者利用英国老龄化纵向研究(English Longitudinal Study of Ageing)的纵向数据进行了分析,结果显示,在 12080 名参与者中,有 2480 人(20-5%)在基线时对行动辅助产品的需求未得到满足,有 5102 人(42-2%)在中位数为 4 年的随访期间至少有一次需求未得到满足。数据进一步显示,在获取方面存在着严重的不公平现象:女性、老年人、教育水平低、财富较少或有残疾的人从无需求过渡到未满足需求的几率更高,此外,女性从未满需求过渡到使用的几率也低于男性。这项研究之所以重要,是因为它不仅为进一步的研究提供了方向,还特别强调了改进政策和实践的必要性。这些研究结果与世界卫生组织和联合国儿童基金会在其《全球辅助技术报告》2 中发布的关于辅助技术需求和使用情况的大型全球横断面研究结果非常吻合。据估计,在人类发展指数非常高的国家,有辅助技术需求的人中有 20%-7%(范围为 16-5-59-8)无法使用辅助技术。
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引用次数: 0
Demographic, socioeconomic, and social barriers to use of mobility assistive products: a multistate analysis of the English Longitudinal Study of Ageing 人口统计,社会经济和社会障碍使用的行动辅助产品:老龄化的纵向研究的多州分析
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-12 DOI: 10.1016/s2468-2667(24)00243-3
Jamie Danemayer, Mikaela Bloomberg, Adam Mills, Cathy Holloway, Shereen Hussein

Background

Cross-sectional evidence suggests that access to essential mobility assistive products (MAPs) might be dependent on non-clinical factors. However, MAP use is better understood as a dynamic process wherein individuals pass through different states of MAP need and use. We aimed to test associations of demographic, socioeconomic, and social factors with transitions between MAP need and use states.

Methods

For this multistate modelling study, data were drawn from 13 years (May, 2006, to July, 2019) of the English Longitudinal Study of Ageing, a prospective cohort study. We included respondents aged 50–89 years who participated in at least two waves of data collection. We used multistate models to examine associations of demographic, socioeconomic, and social factors, including age, sex, education, employment, wealth, marital status, and help with activities of daily living (ADL), with transitions between three main states: no need for MAPs, unmet need for MAPs, and use of MAPs.

Findings

We used data collected from 12 080 respondents (6586 women and 5494 men). During follow-up, 5102 (42·2%) of participants had unmet MAP need and 3330 (27·6%) used MAPs. Women were more likely than men to transition from no need to unmet need (hazard ratio [HR] 1·49, 95% CI 1·38–1·60) and less likely to transition from unmet need to use (0·79, 0·72–0·86). We found an increase in risk of transitioning from no need to unmet need for each 1-year increase in age (1·06, 1·06–1·07), for those with low education level (1·34, 1·23–1·45), those with help with ADL (1·32, 1·16–1·49), and who were not employed (1·22, 1·07–1·40) or disabled (3·83, 2·98–4·93). Similarly, we found an increase in risk of transitioning unmet need to use for each 1-year increase in age (1·06, 1·05–1·06), for those with low education level (1·20, 1·10–1·31), and those with help with ADL (1·25, 1·13–1·38). Increasing wealth was associated with a reduced risk of transitioning from no need to unmet need (0·78, 0·74–0·81) and from unmet need to use (0·94, 0·89–0·99). Single people were more likely to transition from unmet need to use than partnered people (HR 1·21, 95% CI 1·10–1·33).

Interpretation

Women might be disproportionately likely to have unmet MAP needs, whereas other demographic, socioeconomic, and social factors are associated with high MAP need overall. Our findings directly support efforts towards expanding access to assistive products and identifying groups that could particularly benefit. As the first study of its kind to our knowledge, replication with other longitudinal datasets is needed.

Funding

UK Aid.
横断面证据表明,获得基本行动辅助产品(MAPs)可能取决于非临床因素。然而,MAP的使用最好被理解为一个动态过程,在这个过程中,个体经历了不同的MAP需求和使用状态。我们的目的是测试人口、社会经济和社会因素与MAP需求和使用状态之间转变的关系。方法在这项多状态建模研究中,数据来自英国老龄化纵向研究的13年(2006年5月至2019年7月),这是一项前瞻性队列研究。我们包括年龄在50-89岁之间的受访者,他们至少参与了两波数据收集。我们使用多州模型来研究人口、社会经济和社会因素的关联,包括年龄、性别、教育、就业、财富、婚姻状况和日常生活活动(ADL)的帮助,并在三种主要状态之间进行转换:不需要MAPs、未满足MAPs需求和使用MAPs。我们使用了从12080名受访者(6586名女性和5494名男性)中收集的数据。随访期间,5102名(42.2%)参与者未满足MAP需求,3330名(27.6%)参与者使用MAP。女性比男性更有可能从无需求过渡到未满足需求(风险比[HR] 1.49, 95% CI 1.38 - 1.60),而从未满足需求过渡到使用需求的可能性更低(0.79,0.72 - 0.86)。我们发现,年龄每增加1岁,从无需求过渡到未满足需求的风险增加(1.06,1.06 - 1.07),低教育水平(1.34,1.23 - 1.45),帮助ADL(1.32, 1.16 - 1.49),无业(1.22,1.07 - 1.40)或残疾(3.83,2.98 - 4.93)的人。同样,我们发现年龄每增加1岁,过渡需求未满足的风险增加(1.06,1.05 - 1·06),教育水平低的人(1.20,1.10 - 1.31)和ADL帮助者(1.25,1.13 - 1.38)。财富的增加与从无需求到未满足需求(0.78,0.74 - 0.81)和从未满足需求到使用需求(0.94,0.89 - 0.99)过渡的风险降低有关。单身人士比有伴侣的人更容易从未满足的需求过渡到使用需求(HR 1.21, 95% CI 1.10 - 1.33)。妇女可能不成比例地有未满足MAP需求的可能性,而其他人口统计学、社会经济和社会因素与总体上的高MAP需求有关。我们的研究结果直接支持了扩大获得辅助产品和确定可能特别受益的群体的努力。据我们所知,这是同类研究的第一次,需要与其他纵向数据集进行复制。FundingUK援助。
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引用次数: 0
Public health in China: challenges and prospects 中国的公共卫生:挑战与前景
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-04 DOI: 10.1016/s2468-2667(24)00276-7
This December issue of The Lancet Public Health is our annual themed issue on public health in China. It is dedicated to the 1·4 billion people living in China and to the health-care workers, practitioners, and researchers whose work is featured in this issue and presented at The Lancet-Chinese Academy of Medical Sciences Conference held in Beijing on Nov 21–22. Nowadays, China faces four important challenges: the rise in non-communicable diseases (NCDs), an ageing population, escalating costs, and climate change. A collection of research Articles, Comments, Series, and Reviews presents these challenges, but also discusses opportunities and strategies to tackle these public health issues and narrow inequalities.
今年12月的《柳叶刀公共卫生》是我们关于中国公共卫生的年度主题杂志。这篇文章是献给14亿中国人民的,献给那些在11月21日至22日于北京举行的《柳叶刀》-中国医学科学院学术会议上发表文章的卫生保健工作者、从业人员和研究人员。如今,中国面临着四个重要挑战:非传染性疾病(NCDs)的增加、人口老龄化、成本不断上升和气候变化。一系列研究文章、评论、系列和评论提出了这些挑战,但也讨论了解决这些公共卫生问题和缩小不平等现象的机会和战略。
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引用次数: 0
Changes in the epidemiology of under-5 mortality in China from 2016 to 2022: an observational analysis of population-based surveillance data 2016 - 2022年中国5岁以下儿童死亡率流行病学变化:基于人群监测数据的观察性分析
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-04 DOI: 10.1016/s2468-2667(24)00267-6
Chunhua He, Leni Kang, Yuxi Liu, Xue Yu, Qi Li, Juan Liang, Li Dai, Xiaohong Li, Yanping Wang, Jun Zhu, Hanmin Liu
<h3>Background</h3>Sustainable Development Goal (SDG) 3.2 aims to end preventable deaths of newborns and children younger than 5 years. China's progress towards SDG 3.2 has not been evaluated on multiple dimensions. We aimed to assess mortality rates in children younger than 5 years (hereafter referred to as under-5 mortality) and to quantify preventable child mortality and geospatial and temporal trends in child mortality in China from 2016 to 2022.<h3>Methods</h3>In this observational analysis, we used data from the Chinese National Maternal and Child Health Surveillance System (MCHSS) for the period Jan 1, 2016, to Dec 31, 2022 and conducted all-cause mortality and cause-specific mortality analyses for different age groups (age 0–6 days, 7–27 days, 0–27 days, 1–5 months, 6–11 months, 12–23 months, 24–59 months, and birth to 59 months) separately at the national, residential (rural <em>vs</em> urban), and regional (eastern <em>vs</em> central <em>vs</em> western China) levels. All mortality rates were adjusted by age group, type of residency, region, and region-residency strata using a 3-year moving average of the under-reporting rates. National deaths were estimated using the number of livebirths from 2016 to 2022 from the Health Statistics Yearbook of China. Estimated national-level and regional-level mortality rates were weighted by the proportion of the population living in urban and rural areas from the 2010 national census. Optimal survival metrics for neonates and children younger than 5 years were calculated by cause of death in 2020–22 (termed the national optimum), on the basis of the lowest mortality observed among the six region-residency strata.<h3>Findings</h3>In 2022, approximately 65 700 (95% CI 62 700–68 800) children younger than 5 years died in China, with 45·1% (42·7–47·4) of these deaths occurring in the neonatal period (age <28 days). China's under-5 mortality rate decreased from 10·2 deaths (9·9–10·5) per 1000 livebirths in 2016 to 6·8 deaths (6·5–7·2) per 1000 livebirths in 2022; the neonatal mortality rate decreased from 4·9 deaths (4·7–5·1) per 1000 livebirths in 2016 to 3·1 deaths (2·9–3·3) per 1000 livebirths in 2022. The relative risk of death in children younger than 5 years in rural areas compared with urban areas decreased from 2·4 (2·2–2·6) in 2016 to 1·9 (1·7–2·1) in 2022, and in the western region compared with the eastern region decreased from 3·4 (3·0–3·9) in 2016 to 2·3 (1·9–2·8) in 2022. The leading causes of under-5 mortality in 2022 were injuries (23·1% [21·1–25·1] of all-cause deaths), congenital malformations (14·8% [13·1–16·4]), preterm birth complications (14·1% [12·5–15·7]), intrapartum-related events (10·1% [8·7–11·5]), and acute respiratory infections (9·5% [8·2–10·9]). The leading cause of death in the neonatal period was preterm birth complications (12·8% [11·4–14·2] of deaths in children younger than 5 years).<h3>Interpretation</h3>Under-5 mortality in China declined between 2016 and 2022. D
可持续发展目标3.2旨在消除新生儿和5岁以下儿童可预防的死亡。中国在实现可持续发展目标3.2方面的进展尚未得到多维度评估。我们的目的是评估5岁以下儿童的死亡率(以下简称5岁以下儿童死亡率),并量化2016年至2022年中国可预防儿童死亡率和儿童死亡率的地理空间和时间趋势。方法利用2016年1月1日至2022年12月31日中国国家妇幼健康监测系统(MCHSS)的数据,分别对全国、农村和城市不同年龄段(0-6天、7-27天、0-27天、1 - 5个月、6-11个月、12-23个月、24-59个月和出生至59个月)的全因死亡率和病因特异性死亡率进行了分析。以及地区(中国东部、中部和西部)水平。使用低报率的3年移动平均值,按年龄组、居住类型、地区和地区居住阶层调整所有死亡率。根据《中国卫生统计年鉴》2016年至2022年的活产数估算全国死亡人数。根据2010年全国人口普查中生活在城市和农村地区的人口比例,对国家一级和区域一级的估计死亡率进行加权。新生儿和5岁以下儿童的最佳生存指标按2020 - 2022年的死亡原因计算(称为全国最佳),以六个地区居住阶层中观察到的最低死亡率为基础。研究发现,2022年,中国约有65 700 (95% CI 62 700 - 68 800)名5岁以下儿童死亡,其中45.1%(42.7 - 47.4%)的死亡发生在新生儿期(28天)。中国5岁以下儿童死亡率从2016年的每千活产10.2例(9.9 - 10.5例)下降到2022年的每千活产6.8例(6.5 - 7.2例);新生儿死亡率从2016年的每千活产4.9例(4.7 - 5.1例)下降到2022年的每千活产3.1例(2.9 - 3.3例)。农村5岁以下儿童相对死亡危险度由2016年的2.4(2.2 - 2·6)降至2022年的1.9(1.7 - 2.1),西部地区与东部地区相对死亡危险度由2016年的3.4(3.0 - 3.9)降至2022年的2.3(1.9 - 2.8)。2022年5岁以下儿童死亡的主要原因是伤害(占全因死亡的23.1%[21.1 - 25.1])、先天性畸形(14.8%[13.1 - 16.4])、早产并发症(14.1%[12.5 - 15.7])、产时相关事件(10.1%[8.7 - 11.5])和急性呼吸道感染(9.5%[8.2 - 10.9])。新生儿期死亡的主要原因是早产并发症(占5岁以下儿童死亡的12.8%[11.4 - 14.2])。2016年至2022年,中国5岁以下儿童死亡率有所下降。随着时间的推移,地区之间以及城乡之间的差距逐渐缩小,但仍然存在。因此,应努力进一步降低中国的儿童死亡率,包括持续的投资和政策、规划和干预措施的实施,特别是在西部农村地区。
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引用次数: 0
Integrating prevention and treatment: rethinking China's health financing 防治结合:对中国卫生筹资的再思考
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-04 DOI: 10.1016/s2468-2667(24)00247-0
Zhicheng Wang, Kit Yee Chan, Qianyi Xia, Jiantuo Yu, Minghui Ren
Preventive health measures offer superior economic returns compared with the ever-increasing costs of treating established diseases, which place unsustainable pressure on health systems. By reducing the incidence and severity of illness, prevention minimises health-care expenditure and maximises societal welfare by lowering the burden of disease. In China, the principle of making prevention a priority is recognised in the Healthy China 2030 Initiative, which aims to shift the health system's focus towards prevention. However, this goal faces substantial challenges due to structural, legislative, and financial barriers.
与治疗既定疾病的成本不断增加相比,预防性卫生措施提供了更高的经济回报,后者给卫生系统带来了不可持续的压力。通过减少疾病的发病率和严重程度,预防可以最大限度地减少保健支出,并通过降低疾病负担来最大限度地提高社会福利。在中国,“健康中国2030”倡议确认了预防为主的原则,旨在将卫生系统的重点转向预防。然而,由于结构、立法和财政障碍,这一目标面临着重大挑战。
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引用次数: 0
Associations of long-term nitrogen dioxide exposure with a wide spectrum of diseases: a prospective cohort study of 0·5 million Chinese adults 长期二氧化氮暴露与广泛疾病的关系:一项对50万中国成年人的前瞻性队列研究
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-04 DOI: 10.1016/s2468-2667(24)00264-0
Xi Xia, Xia Meng, Cong Liu, Yi Guo, Xinyue Li, Yue Niu, Kin Bong Hubert Lam, Neil Wright, Christiana Kartsonaki, Yiping Chen, Ling Yang, Huaidong Du, Canqing Yu, Dianjianyi Sun, Jun Lv, Junshi Chen, Xiaoming Yang, Ruqin Gao, Shaowei Wu, Haidong Kan, Chan Qu
<h3>Background</h3>Little evidence is available on the long-term health effects of nitrogen dioxide (NO<sub>2</sub>) in low-income and middle-income populations. We investigated the associations of long-term NO<sub>2</sub> exposure with the incidence of a wide spectrum of disease outcomes, based on data from the China Kadoorie Biobank.<h3>Methods</h3>This prospective cohort study involved 512 724 Chinese adults aged 30–79 years recruited from ten areas of China during 2004–08. Time-varying Cox regression models yielded adjusted hazard ratios (HRs) for the associations of long-term NO<sub>2</sub> exposure with aggregated disease incidence endpoints classified by 14 ICD-10 chapters, and incidences of 12 specific diseases selected from three key ICD-10 chapters (cardiovascular, respiratory, and musculoskeletal diseases) found to be robustly associated with NO<sub>2</sub> in the analyses of aggregated endpoints. All models were stratified by age-at-risk (in 1-year scale), study area, and sex, and were adjusted for education, household income, smoking status, alcohol intake, cooking fuel type, heating fuel type, self-reported health status, BMI, physical activity level, temperature, and relative humidity.<h3>Findings</h3>The analysis of 512 709 participants (mean baseline age 52·0 years [SD 10·7]; 59·0% female and 41·0% male) included approximately 6·5 million person-years of follow-up. Between 5285 and 144 852 incident events were recorded for each of the 14 aggregated endpoints. Each 10 μg/m<sup>3</sup> higher annual average NO<sub>2</sub> exposure was associated with higher risks of chapter-specific endpoints, especially cardiovascular (n=144 852; HR 1·04 [95% CI 1·02–1·05]), respiratory (n=73 232; 1·03 [1·01–1·05]), musculoskeletal (n=54 409; 1·11 [1·09–1·14]), and mental and behavioural (n=5361; 1·12 [1·05–1·21]) disorders. Further in-depth analyses on specific diseases found significant positive supra-linear associations with hypertensive disease (1·08 [1·05–1·11]), lower respiratory tract infection (1·03 [1·01–1·06]), arthrosis (1·15 [1·09–1·21]), intervertebral disc disorders (1·13 [1·09–1·17]), and spondylopathies (1·05 [1·01–1·10]), and linear associations with ischaemic heart disease (1·03 [1·00–1·05]), ischaemic stroke (1·08 [1·06–1·11]), and asthma (1·15 [1·04–1·27]), whereas intracerebral haemorrhage (1·00 [0·95–1·06]), other cerebrovascular disease (0·98 [0·96–1·01]), acute upper respiratory infection (1·03 [0·96–1·09]), and chronic lower respiratory disease (0·98 [0·95–1·02]) showed no significant association. NO<sub>2</sub> exposure showed robust null association with external causes (n=32 907; 0·98 [0·95–1·02]) as a negative control.<h3>Interpretation</h3>In China, long-term NO<sub>2</sub> exposure was associated with a range of diseases, particularly cardiovascular, respiratory, and musculoskeletal diseases. These associations underscore the pressing need to implement the recently tightened WHO air quality guidelines.<h3>Funding</h3
背景二氧化氮(NO2)对低收入和中等收入人群的长期健康影响的证据很少。基于中国嘉道里生物银行的数据,我们调查了长期二氧化氮暴露与广泛疾病结局发生率的关系。方法本前瞻性队列研究在2004 - 2008年间从中国10个地区招募了512724名年龄在30-79岁之间的中国成年人。时变Cox回归模型为长期二氧化氮暴露与按14个ICD-10章节分类的总体疾病发病率终点之间的关联产生了调整后的风险比(hr),并在对总体终点的分析中发现,从ICD-10的3个关键章节(心血管、呼吸和肌肉骨骼疾病)中选择的12种特定疾病的发病率与二氧化氮密切相关。所有模型按危险年龄(1年)、研究区域和性别分层,并根据教育程度、家庭收入、吸烟状况、酒精摄入量、烹饪燃料类型、取暖燃料类型、自我报告的健康状况、BMI、身体活动水平、温度和相对湿度进行调整。结果:512 709名参与者(平均基线年龄50.2岁[SD 10.7];59.0%的女性和41.0%的男性)包括大约650万人-年的随访。14个聚合端点中的每一个都记录了5285到144852个事件事件。年平均NO2暴露量每增加10 μg/m3,特定章节终点的风险就会增加,尤其是心血管终点(n=144 852;HR 1.04 [95% CI 1.02 - 1·05])、呼吸系统(n=73 232;1·03[1·01-1·05]),肌肉骨骼(n=54 409;1.11[1.09 - 1.14]),以及心理和行为(n=5361;1·12[1·05-1·21])。对特定疾病的进一步深入分析发现,与高血压疾病(1.08[1.05 - 1·11])、下呼吸道感染(1.03[1.01 - 1·06])、关节病(1.15[1.09 - 1·21])、椎间盘疾病(1.13[1.09 - 1·17])、颈椎病(1.05[1.01 - 1·10])、缺血性心脏病(1.03[1.00 - 1·05])、缺血性卒中(1.08[1.06 - 1·11])、哮喘(1.15[1.04 - 1·27])呈显著的超线性相关。脑出血(1.00[0.95 - 1.06])、其他脑血管疾病(0.98[0.96 - 1.01])、急性上呼吸道感染(1.03[0.96 - 1.09])、慢性下呼吸道疾病(0.98[0.95 - 1.02])无显著相关性。二氧化氮暴露与外因的相关性为零(n=32 907;0·98[0·95-1·02])为阴性对照。在中国,长期暴露于二氧化氮与一系列疾病有关,特别是心血管、呼吸和肌肉骨骼疾病。这些协会强调迫切需要实施世卫组织最近收紧的空气质量指南。资助:惠康基金会、英国医学研究理事会、英国癌症研究中心、英国心脏基金会、中国国家自然科学基金、中国国家重点研发计划、中英奖学金信托基金、嘉道理慈善基金会。
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引用次数: 0
Digital mental health: a potential opportunity to improve health equity in China 数字心理健康:改善中国健康公平的潜在机会
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-04 DOI: 10.1016/s2468-2667(24)00249-4
Hao Fong Sit, Wen Chen, Dan Wu, Yangmu Huang, Dong (Roman) Xu, Brian J Hall
Mental health is an important public health issue in China, compounded by a shortage in psychiatric services. Against this backdrop, digital technologies could offer solutions. Digital mental health interventions use technologies, such as smartphone applications, to improve mental health outcomes. Although there has been a drastic increase in mental health mobile apps available in recent years, current evidence-based digital interventions for mental health are scarce and seldom evaluated for effectiveness and implementation in China. In this Viewpoint, we review digital mental health interventions in China and propose a framework that could guide the development of culturally sensitive digital mental health innovations, with the adoption of co-creation and community engagement strategies. We also provide recommendations to address issues related to usage, interventions, and implementation to improve health equity and implementation of digital mental health interventions in the Chinese context.
在中国,精神卫生是一个重要的公共卫生问题,而精神科服务的短缺更是雪上加霜。在这种背景下,数字技术可以提供解决方案。数字精神卫生干预措施使用智能手机应用程序等技术来改善精神卫生结果。尽管近年来可用的心理健康移动应用程序急剧增加,但目前基于证据的心理健康数字干预措施很少,而且在中国很少评估其有效性和实施情况。在这一观点中,我们回顾了中国的数字心理健康干预措施,并提出了一个框架,该框架可以指导文化敏感的数字心理健康创新的发展,采用共同创造和社区参与战略。我们还提供了建议,以解决与使用、干预和实施相关的问题,以改善中国背景下数字心理健康干预的健康公平性和实施。
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引用次数: 0
All-cause and cause-specific mortality inequalities between people with and without disability: a nationwide data linkage study in Australia 残疾人和非残疾人之间的全因和特定原因死亡率不平等:澳大利亚全国数据联系研究
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-03 DOI: 10.1016/s2468-2667(24)00266-4
Yi Yang, Peter Summers, Zoe Aitken, Anne Kavanagh, George Disney

Background

Without high-quality statistics on mortality inequalities, designing policies to improve the health of people with disability is challenging. We aim to quantify mortality inequalities experienced by people with disability in Australia.

Methods

In this nationwide, data linkage study we used Census mortality linked data (2011–20) to construct a cohort of Australians aged 0–74 years. Disability was measured as requiring assistance or supervision in core daily activities. We estimated age-standardised and age-specific mortality rates, and absolute and relative mortality inequalities between people with and without disability.

Findings

15 216 195 people were included in the study, comprising 7 763 047 females and 7 453 148 males. Of the participants, 258 109 (3·5%) males and 228 658 (2·9%) females reported disability, with 462 990 deaths occurring over 138 540 359 person-years of follow-up. Per 100 000 person-years, there were 2067 (95% CI 2043–2091) more deaths in males and 1697 (1677–1718) more deaths in females with disability (3·69 and 4·64 times higher, respectively) than those without disability. Cancer and cardiovascular disease had the highest absolute inequalities, with rate differences of 462 (95% CI 449–476) for males and 368 (356–379) for females for cancer, and 471 (95% CI 459–483) for males and 333 (324–342) for females for cardiovascular disease. Less common causes among people without disability—neurological conditions, chronic lung diseases, endocrine diseases, and digestive diseases—are relatively common among people with disability, translating to high relative mortality inequalities. The largest relative inequalities were from neurological conditions, with rate ratios of 9·66 (95% CI 9·31–10·02) for males and 11·61 (11·13–12·10) for females. Relative and absolute inequalities were also substantial for unintentional injury and for suicide mortality. Age-specific mortality was consistently higher in people with disability. The leading contributors to absolute inequalities shifted from neurological conditions in younger ages to cancer, cardiovascular diseases, and chronic lung diseases in older ages.

Interpretation

People with disability experience large mortality inequalities. Identifying intervention-amenable factors contributing to these inequalities should be a priority. Targeted interventions and policy reforms to create a more inclusive social and health-care environment for people with disability might be necessary.

Funding

The University of Melbourne.
背景没有关于死亡率不平等的高质量统计数据,制定政策以改善残疾人的健康是具有挑战性的。我们的目标是量化澳大利亚残疾人所经历的死亡率不平等。方法在这项全国性的数据关联研究中,我们使用人口普查死亡率相关数据(2011-20)构建了一个0-74岁的澳大利亚队列。残疾被衡量为在核心日常活动中需要帮助或监督。我们估计了年龄标准化死亡率和特定年龄死亡率,以及残疾人和非残疾人之间的绝对死亡率和相对死亡率不平等。研究结果:15 216 195人参与了这项研究,其中女性7 763 047人,男性7 453 148人。在参与者中,258109名(3.5%)男性和228658名(2.9%)女性报告了残疾,在133840359人年的随访期间,有46990人死亡。每10万人年,残疾男性死亡人数比无残疾男性多2067人(95% CI 2043-2091),残疾女性死亡人数比无残疾女性多1697人(1677-1718)(分别高出3.69倍和4.64倍)。癌症和心血管疾病的绝对不平等程度最高,男性癌症发病率差异为462 (95% CI 449-476),女性癌症发病率差异为368(356-379),男性心血管疾病发病率差异为471 (95% CI 459-483),女性心血管疾病发病率差异为333(324-342)。在非残疾人中不太常见的病因——神经系统疾病、慢性肺病、内分泌疾病和消化系统疾病——在残疾人中相对常见,这导致了较高的相对死亡率不平等。最大的相对不平等来自神经系统疾病,男性的比率为9.66 (95% CI为9.31 - 10.02),女性为11.61(11.13 - 12.10)。相对和绝对的不平等在意外伤害和自杀死亡率方面也很重要。残疾人群按年龄划分的死亡率一直较高。造成绝对不平等的主要因素从年轻人的神经系统疾病转向老年人的癌症、心血管疾病和慢性肺病。残疾人经历了巨大的死亡率不平等。确定导致这些不平等的可干预因素应成为优先事项。可能有必要进行有针对性的干预和政策改革,为残疾人创造一个更具包容性的社会和保健环境。资助墨尔本大学。
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引用次数: 0
Closing the mortality gap for people with disabilities 缩小残疾人死亡率差距
IF 5 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-03 DOI: 10.1016/s2468-2667(24)00274-3
Hannah Kuper, Sara Rotenberg
There are about 1·3 billion people with disability globally, and their higher mortality rates mean that they are dying about 14 years earlier than people without disability.1, 2 In this issue of The Lancet Public Health, Yi Yang and colleagues’ study3 adds to this literature. Using large-scale longitudinal data from 15 million Australians, they showed that people with disability have high inequalities—whether measured on an absolute or relative scale and across different causes of death. Overall, mortality rates were about 3·7-times higher for men with disability and about 4·6-times higher for women with disability than their non-disabled peers. This Article3 adds to the growing, unequivocal evidence on the relationship between mortality and disability. It also highlights three key questions that need to be addressed before public health actors start to take this issue seriously.
全球约有13亿残疾人,他们较高的死亡率意味着他们比非残疾人早死14年左右。在这一期的《柳叶刀公共卫生》杂志上,杨毅及其同事的研究为这一文献提供了补充。他们利用来自1500万澳大利亚人的大规模纵向数据表明,残疾人的不平等程度很高——无论是在绝对规模还是相对规模上,以及在不同的死亡原因上。总的来说,残疾男性的死亡率比非残疾同龄人高出3.7倍,残疾女性的死亡率高出4.6倍。这条增加了关于死亡率和残疾之间关系的越来越明确的证据。它还强调了在公共卫生行为体开始认真对待这一问题之前需要解决的三个关键问题。
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引用次数: 0
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Lancet Public Health
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