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Proximal femur diaphysis osteoid osteoma mimicking lumbar radiculopathy. 模拟腰椎神经根病的股骨近端骨干类骨瘤。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.10653
Rekib Saçaklıdır, Leyla Huseynli, Savaş Şencan, Osman Hakan Gündüz

Osteoid osteoma is a benign bone tumor that commonly arises from the metaphyseal and diaphyseal regions of long bones. Pain is often the first symptom, and it can mimic many diseases. Herein, we report a 36-year-old male patient who presented with complaints of lower back pain radiating to the right extremity for a year. In the patient's history, physical therapy, platelet-rich plasma, pregabalin, and duloxetine were used, with the only benefit from indomethacin. An X-ray of the femur was requested, and the diagnosis of osteoid osteoma was confirmed by magnetic resonance imaging. Osteoid osteoma should be kept in mind as a differential diagnosis of persistent pain despite treatment.

骨样骨瘤是一种良性骨肿瘤,通常发生在长骨的干骺端和干骺端。疼痛通常是第一症状,它可以模拟许多疾病。在此,我们报告一位36岁的男性患者,他的主诉是腰痛放射到右肢一年。在患者的病史中,使用了物理治疗、富血小板血浆、普瑞巴林和度洛西汀,唯一的益处是吲哚美辛。要求对股骨进行x光检查,并通过磁共振成像确诊为骨样骨瘤。骨样骨瘤应牢记为鉴别诊断的持续疼痛,尽管治疗。
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引用次数: 0
The effectiveness of peroneal nerve stimulation combined with neuromuscular electrical stimulation in the management of knee osteoarthritis: A randomized controlled single-blind study. 腓神经刺激联合神经肌肉电刺激治疗膝骨性关节炎的有效性:一项随机对照单盲研究。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.10998
Özgür Yeşilöz, Meliha Kasapoğlu Aksoy

Objectives: This study aimed to compare the effectiveness of neuromuscular electrical stimulation (NMES) combined with peroneal nerve stimulation (PNS) on muscle strength around the knee, proprioception, pain, functional status, and quality of life in patients with knee osteoarthritis (OA).

Patients and methods: The prospective, randomized, single-blinded, controlled trial included 63 patients with clinical and radiological diagnoses of knee OA between December 2019 and March 2020. The patients were divided into two groups: Group 1 (NMES+PNS, n=31) and Group 2 (NMES, n=32). The patients were followed up at two and six weeks. Main outcome measures were the Visual Analog Scale, Western Ontario and McMaster Universities Arthritis Index, Nottingham Health Profile, and 100-m walking test, quadriceps muscle strength, hamstring muscle strength (HMS), and joint position sense were evaluated using a computer-controlled isokinetic dynamometer at 60°/sec, 90°/sec, and 120°/sec angular velocities. The proprioception was evaluated at 30° and 60° flexion angles using the same device.

Results: Two patients from Group 1 and two patients from Group 2 were excluded from the study after they failed to show up for the six-week control. As a result, the study was completed with 59 patients (30 females, 29 males; 55.9±6.1 years; range, 40 to 65 years). There was a significant difference between the two groups in the 100-m walking test parameter at the six-week control in favor of Group 1 (p<0.05). There was a significant difference in favor of Group 1 in the parameters of proprioception (30° and 60°) and HMS (60° and 90°) in both the two-week evaluation and six-week controls (p<0.05). The HMS 120° parameter showed a significant difference in favor of Group 1 at the six-week control (p<0.05).

Conclusion: In patients with knee OA, we believe that PNS combined with NMES may be more effective than NMES treatment alone in terms of proprioception, HMS, and functional status.

目的:本研究旨在比较神经肌肉电刺激(NMES)联合腓神经刺激(PNS)对膝关节周围肌肉力量、本体感觉、疼痛、功能状态和生活质量的影响。患者和方法:这项前瞻性、随机、单盲、对照试验纳入了2019年12月至2020年3月期间63例临床和影像学诊断为膝关节OA的患者。将患者分为两组:1组(NMES+PNS, n=31)和2组(NMES, n=32)。在两周和六周时对患者进行随访。主要结果测量是视觉模拟量表、西安大略和麦克马斯特大学关节炎指数、诺丁汉健康概况、100米步行测试、股四头肌力量、腘绳肌力量(HMS)和关节位置感,使用计算机控制的等速测力仪在60°/秒、90°/秒和120°/秒角速度下进行评估。使用相同的装置在30°和60°屈曲角度下评估本体感觉。结果:1组2例患者和2组2例患者在6周的对照组未出现后被排除在研究之外。结果,研究完成了59例患者(女性30例,男性29例;55.9±6.1年;范围:40至65岁)。两组在6周对照时的100米步行测试参数有显著差异,1组更有利(p结论:在膝关节OA患者中,我们认为PNS联合NMES在本体感觉、HMS和功能状态方面可能比单独NMES治疗更有效。
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引用次数: 0
The effect of high-frequency repetitive transcranial magnetic stimulation on motor recovery and gait parameters in chronic incomplete spinal cord injury: A randomized-controlled study. 高频重复经颅磁刺激对慢性不完全性脊髓损伤运动恢复和步态参数的影响:一项随机对照研究。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.11585
Serdar Kesikburun, Ayça Uran Şan, Evren Yaşar, Bilge Yılmaz

Objectives: This study aims to examine the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on gait parameters and lower extremity motor recovery in a more specific sample of individuals with chronic and traumatic incomplete spinal cord injury (iSCI).

Patients and methods: This double-blind, sham-controlled, randomized study included a total of 28 individuals (20 males, 8 females; mean age: 35.7±12.1 years; range, 18 to 45 years) with chronic (>1 year) traumatic iSCI. The participants were randomly allocated to either sham rTMS group (n=14) or real rTMS group (n=14). We compared the groups based on the lower extremity motor scores (LEMS), the temporal-spatial gait measurements using three-dimensional gait analysis, the Walking Index for SCI-II (WISCI-II), and 10-m walking test at baseline, three weeks (post-treatment) and five weeks (follow-up) after the treatment.

Results: The real rTMS group revealed a significant improvement in walking speed, LEMS score, and 10-m walking test after the treatment compared to baseline (p=0.001, p=0.002, and p=0.023, respectively). Changes in the LEMS score were significantly increased in the real rTMS group compared to the sham group at both three and five weeks (p=0.001 and p=0.001, respectively). No significant difference was observed in the other variables between the groups (p>0.05).

Conclusion: Our study findings support the therapeutic effectiveness of rTMS on motor recovery in chronic iSCI. The rTMS can be used as an adjuvant therapy to conventional physiotherapy in the rehabilitation of patients with iSCI.

目的:本研究旨在研究高频重复经颅磁刺激(rTMS)对慢性和外伤性不完全性脊髓损伤(iSCI)患者步态参数和下肢运动恢复的影响。患者和方法:这项双盲、假对照、随机研究共纳入28人(男性20人,女性8人;平均年龄:35.7±12.1岁;年龄范围:18 - 45岁),慢性(>1年)创伤性iSCI。参与者被随机分配到假rTMS组(n=14)和真rTMS组(n=14)。在基线、治疗后3周和5周的随访中,我们根据下肢运动评分(LEMS)、三维步态分析的时空步态测量、SCI-II步行指数(WISCI-II)和10米步行测试对两组进行比较。结果:real rTMS组治疗后步行速度、LEMS评分、10m步行测试均较基线有显著改善(p=0.001、p=0.002、p=0.023)。在第3周和第5周,与假手术组相比,真实rTMS组的LEMS评分变化显著增加(p=0.001和p=0.001)。其他指标各组间差异无统计学意义(p>0.05)。结论:我们的研究结果支持rTMS对慢性iSCI运动恢复的治疗效果。rTMS可作为iSCI患者常规物理治疗康复的辅助治疗。
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引用次数: 0
Efficiency of therapeutic underwater ultrasound therapy in mild-to-moderate carpal tunnel syndrome: A randomized sham-controlled study. 治疗性水下超声治疗轻至中度腕管综合征的疗效:一项随机假对照研究。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.12467
Sinan Bagcaci, Ramazan Yilmaz, Nilay Sahin

Objectives: This study aimed to evaluate the efficiency of therapeutic pulsed ultrasound (US) applied underwater in mild-to-moderate carpal tunnel syndrome (CTS).

Patients and methods: This randomized, placebo-controlled study included 75 patients (114 hands; 7 males, 68 females; mean age: 46.7±9.9 years; range, 24 to 64 years) diagnosed with CTS through clinical evaluation and electroneuromyography (ENMG) results between March 2012 and January 2013. Patients were randomized into three groups. Group 1 received underwater pulsed US, Group 2 received sham US, and Group 3 was the control group. All groups were given night splints. Patients were evaluated at baseline, at the end of treatment (two weeks), and 12 weeks after the treatment using clinical examination tests (Tinel, Phalen, and hand elevation test), hand grip strength, Visual Analog Scale (VAS) for pain, Pain Quality Assessment Scale (PQAS), and ENMG.

Results: In all groups, a significant improvement was detected in the clinical assessment parameters, including the pain VAS, PQAS scores, physical examination outcomes, and hand grip strength. The decrease in VAS score and PQAS was found to be superior in the pulsed US group at both two weeks after the treatment and at the 12th week after the treatment compared to the sham US and control groups (p<0.001). Improvement in ENMG parameters, such as median motor latency, median sensorial velocity, and median sensory latency, was observed only in the underwater pulsed US group (p<0.001).

Conclusion: Therapeutic underwater pulsed US is an effective, safe, and easy-to-apply treatment option in the conservative treatment of mild-to-moderate CTS.

目的:评价脉冲超声(US)水下应用治疗轻中度腕管综合征(CTS)的疗效。患者和方法:这项随机、安慰剂对照的研究包括75例患者(114手;男性7人,女性68人;平均年龄46.7±9.9岁;在2012年3月至2013年1月期间,通过临床评估和神经肌电图(ENMG)结果诊断为CTS,年龄在24至64岁之间。患者随机分为三组。1组采用水下脉冲超声,2组采用假超声,3组为对照组。所有组均给予夜间夹板。在基线、治疗结束(2周)和治疗后12周,采用临床检查测试(Tinel、Phalen和手部抬高试验)、手部握力、疼痛视觉模拟量表(VAS)、疼痛质量评估量表(PQAS)和ENMG对患者进行评估。结果:两组患者疼痛VAS评分、PQAS评分、体格检查结果、手部握力等临床评价指标均有显著改善。在治疗后2周和治疗后12周,脉冲US组的VAS评分和PQAS的下降均优于假US组和对照组(p结论:治疗性水下脉冲US是一种有效、安全、易于应用的治疗方案,适用于轻中度CTS保守治疗。
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引用次数: 0
Comparison of the efficacy of oxygen-ozone and lidocaine injections in the treatment of myofascial pain syndrome: A randomized clinical trial. 氧-臭氧与利多卡因注射治疗肌筋膜疼痛综合征的疗效比较:一项随机临床试验。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.11516
Nurdan Korkmaz, Merve Örücü Atar, Sinem Uyar Köylü, Sefa Gümrük Aslan, Özge Tezen, Serdar Kesikburun

Objectives: This study aims to compare effectiveness of oxygen-ozone injection versus lidocaine injection on the trigger point in the treatment of myofascial pain syndrome (MPS).

Patients and methods: Between April 2021 and December 2021, a total of 46 patients with MPS (8 males, 38 females; mean age: 44.7±10.4 years; range, 25 to 65 years) were included. The patients were randomized to either ozone injection (n=23) or lidocaine injection (n=23) groups. All injections were administered once a week for three consecutive weeks. The primary outcome measure was the pain severity assessed by Visual Analog Scale (VAS). Secondary outcome measures were cervical lateral flexion range of motion (ROM), pain score (PS), and Neck Disability Index (NDI). The measurements were performed before the treatment, and at four and 12 weeks after treatment.

Results: There was a significant effect of time for VAS, PS, and NDI scores in both groups. Compared to baseline versus Weeks 4 and 12, the VAS, PS, and NDI scores significantly decreased over time in both groups (p<0.001 for all). A significant group X time interaction was identified regarding the VAS scores. The mean difference in the VAS scores over time was significantly higher in the lidocaine group compared to the oxygen-ozone group (p=0.028).

Conclusion: Oxygen-ozone and lidocaine injections of the trigger point can effectively improve pain and functional status. However, lidocaine injection appears to be superior in reducing pain compared to oxygen-ozone injection, but is not superior in improving function and PS.

目的:比较氧臭氧注射与利多卡因注射对肌筋膜疼痛综合征(MPS)触发点的影响。患者和方法:2021年4月至2021年12月,共46例MPS患者(男性8例,女性38例;平均年龄:44.7±10.4岁;范围,25至65岁)。将患者随机分为臭氧注射组(n=23)和利多卡因注射组(n=23)。所有注射每周一次,连续三周。主要结局指标是用视觉模拟量表(VAS)评估疼痛严重程度。次要结局指标为颈椎侧屈活动度(ROM)、疼痛评分(PS)和颈部残疾指数(NDI)。这些测量分别在治疗前、治疗后4周和12周进行。结果:时间对两组患者VAS、PS、NDI评分均有显著影响。与基线相比,与第4周和第12周相比,两组患者的VAS、PS和NDI评分均随着时间的推移而显著降低(结论:触发点注射氧臭氧和利多卡因可有效改善疼痛和功能状态。然而,利多卡因在减轻疼痛方面优于氧臭氧注射,但在改善功能和PS方面并不优于氧臭氧注射。
{"title":"Comparison of the efficacy of oxygen-ozone and lidocaine injections in the treatment of myofascial pain syndrome: A randomized clinical trial.","authors":"Nurdan Korkmaz,&nbsp;Merve Örücü Atar,&nbsp;Sinem Uyar Köylü,&nbsp;Sefa Gümrük Aslan,&nbsp;Özge Tezen,&nbsp;Serdar Kesikburun","doi":"10.5606/tftrd.2023.11516","DOIUrl":"https://doi.org/10.5606/tftrd.2023.11516","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare effectiveness of oxygen-ozone injection versus lidocaine injection on the trigger point in the treatment of myofascial pain syndrome (MPS).</p><p><strong>Patients and methods: </strong>Between April 2021 and December 2021, a total of 46 patients with MPS (8 males, 38 females; mean age: 44.7±10.4 years; range, 25 to 65 years) were included. The patients were randomized to either ozone injection (n=23) or lidocaine injection (n=23) groups. All injections were administered once a week for three consecutive weeks. The primary outcome measure was the pain severity assessed by Visual Analog Scale (VAS). Secondary outcome measures were cervical lateral flexion range of motion (ROM), pain score (PS), and Neck Disability Index (NDI). The measurements were performed before the treatment, and at four and 12 weeks after treatment.</p><p><strong>Results: </strong>There was a significant effect of time for VAS, PS, and NDI scores in both groups. Compared to baseline versus Weeks 4 and 12, the VAS, PS, and NDI scores significantly decreased over time in both groups (p<0.001 for all). A significant group X time interaction was identified regarding the VAS scores. The mean difference in the VAS scores over time was significantly higher in the lidocaine group compared to the oxygen-ozone group (p=0.028).</p><p><strong>Conclusion: </strong>Oxygen-ozone and lidocaine injections of the trigger point can effectively improve pain and functional status. However, lidocaine injection appears to be superior in reducing pain compared to oxygen-ozone injection, but is not superior in improving function and PS.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"294-302"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/47/b2/TurkJPhysMedRehab-69-294.PMC10478539.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10177863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of transcutaneous auricular vagus nerve stimulation on visual memory performance and fatigue. 经皮耳迷走神经刺激对视觉记忆和疲劳的影响。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.11174
Rıdvan Yıldız, Ali Veysel Özden, Onur Seçgin Nişancı, Zeynep Yıldız Kızkın, Bedriye Cansu Demirkıran

Objectives: This study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on visual memory performance and fatigue in healthy individuals.

Patients and methods: Between April 10, 2022 and May 25, 2022, a total of 60 physical therapy and rehabilitation students (27 males, 33 females; mean age: 20.6±1.6 years; range, 18 to 24 years) were included in the study. The individuals were divided into two groups as the experimental group (n=30) and the control group (n=30). The experimental group received taVNS, mobile device supported games, and low-medium intensity aerobic exercises, while the control group received mobile device supported games and aerobic exercises. The personal information form was applied to all participants. The level of fatigue was measured using a computer-based evaluation and Fatigue Severity Scale (FSS) to analyze the visual memory performance.

Results: All parameters used to evaluate visual memory performance showed a significant difference, while the FSS scores showed no significant difference (p>0.05). Only one sub-parameter in the control group was significantly different, while none of the other sub-parameters or FSS scores were significantly different (p>0.05). There was a significant difference between the two groups in terms of two of the visual memory sub-parameters, although no significant difference was found for the results of one parameter and the FSS (p>0.05).

Conclusion: Our study results show that taVNS can produce positive effects on visual memory performance, although it does not apparently affect fatigue.

目的:探讨经皮耳迷走神经刺激(taVNS)对正常人视觉记忆和疲劳的影响。患者与方法:2022年4月10日至2022年5月25日,共60名物理治疗与康复专业学生(男27名,女33名;平均年龄:20.6±1.6岁;年龄从18岁到24岁不等)。将个体分为实验组(n=30)和对照组(n=30)两组。实验组接受taVNS、移动设备支持的游戏和中低强度有氧运动,对照组接受移动设备支持的游戏和有氧运动。个人信息表适用于所有参与者。使用基于计算机的评估和疲劳严重程度量表(FSS)来测量疲劳水平,以分析视觉记忆性能。结果:两组视觉记忆评分差异有统计学意义(p>0.05), FSS评分差异无统计学意义(p>0.05)。对照组仅1个子参数差异有统计学意义,其他子参数及FSS评分无统计学意义(p>0.05)。两组在视觉记忆的两个子参数上差异有统计学意义(p>0.05),但其中一个参数与FSS的结果差异无统计学意义(p>0.05)。结论:我们的研究结果表明,taVNS对视觉记忆有积极的影响,但对疲劳没有明显的影响。
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引用次数: 0
An unusual cause of posterior interosseous nerve palsy and contribution of ultrasonography to electromyography in a patient with neurofibroma. 神经纤维瘤后骨间神经麻痹的不寻常病因及超声对肌电图的贡献。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.9881
Deniz Palamar, Kenan Akgün, Tuğçe Özekli Mısırlıoğlu, Rana Terlemez, Atakan Aydın, Meral Erdemir Kızıltan

Neurofibroma, a benign peripheral nerve sheath tumor, represents a rare cause of posterior interosseous nerve syndrome. Electrodiagnostic studies may not identify the exact site of nerve compression, a possible lesion that compresses the nerve and do not provide information about the morphological changes. Ultrasound is a cost-effective, practical modality that provides the opportunity for dynamic tracking in the peripheral nerves, and it is widely considered as the initial imaging modality for peripheral nerves. Herein, we report a case of posterior interosseous nerve palsy in a 13-year-old boy with neurofibroma of posterior interosseous nerve diagnosed with ultrasound. The benefit of ultrasound in localizing and determining the etiology of the posterior interosseous nerve palsy is emphasized in this case report. A meticulous ultrasound examination is recommended in suspected peripheral nerve lesions, regardless of the results of electrophysiological and imaging modalities.

神经纤维瘤是一种良性周围神经鞘肿瘤,是一种罕见的后骨间神经综合征的病因。电诊断研究可能不能确定神经压迫的确切位置,一种可能压迫神经的病变,也不能提供形态学变化的信息。超声是一种经济、实用的方式,为周围神经的动态跟踪提供了机会,被广泛认为是周围神经的初始成像方式。在此,我们报告一例后骨间神经麻痹的13岁男孩与后骨间神经纤维瘤的超声诊断。本病例报告强调超声在定位和确定后骨间神经麻痹病因方面的优势。在怀疑周围神经病变时,建议进行细致的超声检查,不管电生理和成像方式的结果如何。
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引用次数: 0
A case of pseudogout attack after zoledronic acid treatment in primary hyperparathyroidism. 唑来膦酸治疗原发性甲状旁腺功能亢进后假性发作1例。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.10135
Meriç Coşkun, Emre Demir, Abdurrahman Tufan, Afruz Babayeva, Mehmet Muhittin Yalçın, Alev Altınova, Müjde Aktürk, İlhan Yetkin

Pseudogout (PG) is an inflammatory arthropathy that develops due to the accumulation of calcium pyrophosphate dihydrate crystals in synovial structures. Herein, we present a 59-year-old male patient with PG developed as a result of zoledronic acid (ZA) infusion, which was administered due to primary hyperparathyroidism. The patient with parathyroid adenoma was given ZA since the calcium level did not decrease despite intravenous saline and loop diuretic. One day after ZA administration, the patient had severe pain, fever, and swelling in joints. The radiograph showed chondrocalcinosis. Calcium pyrophosphate deposition were observed in the arthrocentesis fluid under polarized light. The patient's symptoms regressed after anakinra and colchicine treatment. To the best of our knowledge, this is the first case report of a PG attack after ZA treatment for primary hyperparathyroidism. Additionally, there have been few cases of PG after bisphosphonate treatment for osteoporosis in the literature, signifying that more care should be taken when administering bisphosphonate therapy in patients with risk factors.

假脱位(PG)是一种炎性关节病,是由于滑膜结构中焦磷酸钙二水合物晶体的积累而发展起来的。在此,我们报告了一位59岁的男性患者,由于原发性甲状旁腺功能亢进而输注唑来磷酸(ZA)而发展为PG。甲状旁腺瘤患者在静脉注射生理盐水和利尿剂后钙水平没有下降,因此给予ZA。服用ZA后1天,患者出现剧烈疼痛、发热、关节肿胀。x线片显示软骨钙质增多症。偏振光下观察到关节积液中焦磷酸钙沉积。经阿那白和秋水仙碱治疗后,患者症状有所缓解。据我们所知,这是第一例在ZA治疗原发性甲状旁腺功能亢进后PG发作的病例报告。此外,文献中双膦酸盐治疗骨质疏松症后发生PG的病例很少,这表明对有危险因素的患者进行双膦酸盐治疗时应更加小心。
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引用次数: 1
Isokinetic strength training versus core stability training on the trunk muscle strength and quality of life after surgical repair of incisional hernia in adolescents. 等速力量训练与核心稳定性训练对青少年切口疝手术修复后躯干肌肉力量和生活质量的影响。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.12217
Özge İpek Dongaz, Asalet Aybüke Güp
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引用次数: 0
The relationship between inadequate response to physical therapy and central sensitization in patients with knee osteoarthritis: A prospective cohort study. 膝骨关节炎患者对物理治疗反应不足与中枢致敏的关系:一项前瞻性队列研究。
IF 1.3 4区 医学 Q3 REHABILITATION Pub Date : 2023-09-01 DOI: 10.5606/tftrd.2023.12020
Serkan Burak Yüzügüldü, Şehim Kutlay, Haydar Gök

Objectives: This study aims to investigate the relationship between physical therapy response and the presence of central sensitization (CS) in patients with painful knee osteoarthritis (OA). Patients and methods: Between May 2019 and March 2020, a total of 84 patients with knee OA (12 males, 72 females; mean age: 60.7±7.7 years; range 50 to 74 years) and 30 age and sex-matched controls (6 males, 24 females; mean age: 59.2±8.9 years; range 50 to 75 years) were included in this study. Knee pain and functional status were evaluated by Visual Analog Scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Structural damage was assessed by knee radiography. The Central Sensitization Inventory (CSI), Beck Depression Inventory (BDI), Insomnia Severity Index (ISI), Pain Catastrophizing Scale (PCS), and PainDETECT Questionnaire (PDQ) were applied at baseline. Pain pressure thresholds (PPTs) of the patients were measured and compared with the control group. All patients underwent a total of 15 sessions of physical therapy program for five sessions/weekly. After treatment, the patients were divided into two groups as responders and non-responders according to the Osteoarthritis Research Society International (OARSI) criteria. Results: The CSI score of the patients in non-responder group was significantly higher compared to the responder group (p=0.004). Using a cut-off value of ≥40, the proportion of patients with CSI scores of ≥40 was significantly lower in the responder group compared to non-responder group (p=0.021). The PPT measurement values were significantly lower in the non-responder group compared to the responder and control groups (p <0.01). There was a significant difference in the frequency of hyperalgesia between the groups (p=0.021). Central sensitization and depression were the most significant predictors of non-response to physical therapy (p=0.045 and p=0.024, respectively). Conclusion: Our study results suggest the presence of CS and depression may result in an inadequate response to physical therapy in patients with knee OA. Clinicians should consider the findings of CS and depression in treatment planning.

目的:本研究旨在探讨疼痛性膝骨关节炎(OA)患者物理治疗反应与中枢致敏(CS)存在的关系。患者和方法:2019年5月至2020年3月,共84例膝关节OA患者(男性12例,女性72例;平均年龄:60.7±7.7岁;50至74岁)和30名年龄和性别匹配的对照组(6名男性,24名女性;平均年龄59.2±8.9岁;年龄在50 - 75岁之间)。采用视觉模拟量表(VAS)和西部安大略和麦克马斯特大学骨关节炎指数(WOMAC)评估膝关节疼痛和功能状态。通过膝关节x线摄影评估结构损伤。基线采用中枢致敏性量表(CSI)、贝克抑郁量表(BDI)、失眠严重程度指数(ISI)、疼痛灾难化量表(PCS)和疼痛检测问卷(PDQ)。测量患者的疼痛压力阈值(PPTs),并与对照组进行比较。所有患者共接受15次物理治疗,每周5次。治疗后,根据国际骨关节炎研究协会(OARSI)的标准,将患者分为有反应和无反应两组。结果:无反应组患者的CSI评分明显高于有反应组(p=0.004)。采用临界值≥40,反应组CSI评分≥40的患者比例明显低于无反应组(p=0.021)。与有反应组和对照组相比,无反应组的PPT测量值显著降低(p)。结论:我们的研究结果表明,CS和抑郁的存在可能导致膝关节OA患者对物理治疗的反应不足。临床医生在制定治疗计划时应考虑CS和抑郁症的结果。
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Turkish Journal of Physical Medicine and Rehabilitation
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