Pub Date : 2023-09-01DOI: 10.5606/tftrd.2023.12933
Yasin Demir
One of the most important parameters of prosthesis rehabilitation is to determine the most suitable prosthesis in patients with upper extremity amputation. When deciding on the prosthesis, the clinical features of the amputee should be highly matched with the predicted prosthesis. Prescribing the most suitable prosthesis and minimizing the mismatch can be possible with a detailed prosthetic evaluation.
{"title":"Upper limb prosthetic prescription.","authors":"Yasin Demir","doi":"10.5606/tftrd.2023.12933","DOIUrl":"https://doi.org/10.5606/tftrd.2023.12933","url":null,"abstract":"<p><p>One of the most important parameters of prosthesis rehabilitation is to determine the most suitable prosthesis in patients with upper extremity amputation. When deciding on the prosthesis, the clinical features of the amputee should be highly matched with the predicted prosthesis. Prescribing the most suitable prosthesis and minimizing the mismatch can be possible with a detailed prosthetic evaluation.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"261-265"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/90/cf/TurkJPhysMedRehab-69-261.PMC10478545.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.5606/tftrd.2023.11440
Meltem Puşuroğlu, Mehmet Serhat Topaloğlu, Çiçek Hocaoğlu, Murat Yıldırım
Objectives: This study aimed to examine emotional awareness, control of emotions, and the childhood attachment process in fibromyalgia patients.
Patients and methods: The observational study was conducted with 117 participants (14 males, 103 females; mean age: 43.9±9.0 years; range, 22 to 64 years) between February 20, 2022, and May 20, 2022. Sixty-one patients and 56 healthy control subjects filled out a form including sociodemographic data, such as age, sex, occupation, and educational status. In addition, the participants answered the Expressing Emotions Scale, Rejection Sensitivity Scale, and Experiences in Close Relationships Scale.
Results: In our study, Expressing Emotions Scale scores are significantly higher in the healthy control group than in the patient group (p<0.05). Rejection Sensitivity Scale scores are significantly higher in the patient group than in the healthy control group (p<0.05). In the Experiences in Close Relationships Scale, a significant difference was determined between the patient and control groups in the avoidant attachment subdimension (p<0.05). Similarly, a significant difference was observed between both groups in terms of the anxiety attachment subdimension (p<0.05).
Conclusion: The ability to express emotions is lower and avoidant and anxious attachment rates are higher in fibromyalgia patients.
{"title":"Expressing emotions, rejection sensitivity, and attachment in patients with fibromyalgia.","authors":"Meltem Puşuroğlu, Mehmet Serhat Topaloğlu, Çiçek Hocaoğlu, Murat Yıldırım","doi":"10.5606/tftrd.2023.11440","DOIUrl":"https://doi.org/10.5606/tftrd.2023.11440","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to examine emotional awareness, control of emotions, and the childhood attachment process in fibromyalgia patients.</p><p><strong>Patients and methods: </strong>The observational study was conducted with 117 participants (14 males, 103 females; mean age: 43.9±9.0 years; range, 22 to 64 years) between February 20, 2022, and May 20, 2022. Sixty-one patients and 56 healthy control subjects filled out a form including sociodemographic data, such as age, sex, occupation, and educational status. In addition, the participants answered the Expressing Emotions Scale, Rejection Sensitivity Scale, and Experiences in Close Relationships Scale.</p><p><strong>Results: </strong>In our study, Expressing Emotions Scale scores are significantly higher in the healthy control group than in the patient group (p<0.05). Rejection Sensitivity Scale scores are significantly higher in the patient group than in the healthy control group (p<0.05). In the Experiences in Close Relationships Scale, a significant difference was determined between the patient and control groups in the avoidant attachment subdimension (p<0.05). Similarly, a significant difference was observed between both groups in terms of the anxiety attachment subdimension (p<0.05).</p><p><strong>Conclusion: </strong>The ability to express emotions is lower and avoidant and anxious attachment rates are higher in fibromyalgia patients.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"303-308"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/40/TurkJPhysMedRehab-69-303.PMC10478538.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.5606/tftrd.2023.11002
Başak Mansız-Kaplan, Mustafa Sırrı Kotanoğlu, Koray Gürsoy, Seçil Vural, Gökhan Koca, Barış Nacır, Nihat Yumuşak, Halil Kara, Selcen Yüksel, Meliha Korkmaz
Objectives: This study aims to investigate the electrophysiological, scintigraphic, and histopathological effects of pitavastatin and its impact on functional status in rats with sciatic nerve injury.
Materials and methods: A total of 30 Wistar albino rats were divided into three equal groups including 10 rats in each group: sham group (no injury), control group (nerve injury induced), and pitavastatin group (nerve injury induced and 2 mg/kg of pitavastatin administered orally once a day for 21 days). Before and at the end of intervention, quantitative gait analysis with the CatWalk system and sciatic nerve conduction studies were performed. After the intervention, the gastrocnemius muscle was scintigraphically evaluated, and the sciatic nerve was histopathologically examined.
Results: There was no significant difference in the sciatic nerve conduction before the intervention and Day 21 among the groups (p>0.05). According to the quantitative gait analysis, there were significant differences in the control group in terms of the individual, static, dynamic, and coordination parameters (p<0.05). The histopathological examination revealed a significant difference in the total myelinated axon count and mean axon diameter among the groups (p<0.001).
Conclusion: Pitavastatin is effective in nerve regeneration and motor function recovery in rats with sciatic nerve injury.
{"title":"Evaluation of the effect of pitavastatin on motor deficit and functional recovery in sciatic nerve injury: A CatWalk study.","authors":"Başak Mansız-Kaplan, Mustafa Sırrı Kotanoğlu, Koray Gürsoy, Seçil Vural, Gökhan Koca, Barış Nacır, Nihat Yumuşak, Halil Kara, Selcen Yüksel, Meliha Korkmaz","doi":"10.5606/tftrd.2023.11002","DOIUrl":"https://doi.org/10.5606/tftrd.2023.11002","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the electrophysiological, scintigraphic, and histopathological effects of pitavastatin and its impact on functional status in rats with sciatic nerve injury.</p><p><strong>Materials and methods: </strong>A total of 30 Wistar albino rats were divided into three equal groups including 10 rats in each group: sham group (no injury), control group (nerve injury induced), and pitavastatin group (nerve injury induced and 2 mg/kg of pitavastatin administered orally once a day for 21 days). Before and at the end of intervention, quantitative gait analysis with the CatWalk system and sciatic nerve conduction studies were performed. After the intervention, the gastrocnemius muscle was scintigraphically evaluated, and the sciatic nerve was histopathologically examined.</p><p><strong>Results: </strong>There was no significant difference in the sciatic nerve conduction before the intervention and Day 21 among the groups (p>0.05). According to the quantitative gait analysis, there were significant differences in the control group in terms of the individual, static, dynamic, and coordination parameters (p<0.05). The histopathological examination revealed a significant difference in the total myelinated axon count and mean axon diameter among the groups (p<0.001).</p><p><strong>Conclusion: </strong>Pitavastatin is effective in nerve regeneration and motor function recovery in rats with sciatic nerve injury.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"334-343"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/37/e0/TurkJPhysMedRehab-69-334.PMC10478549.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10171079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.5606/tftrd.2023.10931
Halit Fidancı, İlker Öztürk, Şencan Buturak, Mehmet Yıldız, Zülfikar Arlier
Objectives: This study investigated whether peroneal nerve F-wave persistence increased when the Jendrassik maneuver (JM) was performed, aiming to obtain information about the physiology of F-waves and JM.
Patients and methods: Thirty healthy individuals (HIs; 17 females, 13 males; mean age: 33.6±8.2 years; range, 23-50 years) were included in the prospective experimental study conducted between June 15, 2021, and December 15, 2021. Nerve conduction studies of peroneal, superficial peroneal, posterior tibial, and sural nerves were performed in one extremity of each HI. The peroneal nerve F-wave study was performed at rest (Study 1), during JM (Study 2), and after JM (Study 3). F-wave persistence of the peroneal nerve, maximum F-wave amplitude (ampF-wavemax), mean F-wave amplitude (ampF-wavemean), minimum F-wave latency, and the ratio of ampF-wavemean to maximum M amplitude (F/M ratio) were analyzed.
Results: The mean peroneal nerve F-wave persistence in Study 1, Study 2, and Study 3 was 28.7±23.9%, 52.3±32.1%, and 34.7±29.0%, respectively. F-wave persistence in Study 2 was higher compared to Studies 1 and 3 (p<0.001 and p<0.001, respectively). Moreover, ampF-wavemax, ampF-wavemean, and F/M ratio in Study 2 were higher than Studies 1 and 3 (p=0.026 and p=0.021 for ampF-wavemean; p=0.015 and p=0.003 for ampF-wavemax; p=0.033 and p=0.015 for F/M ratio, respectively). F-wave persistence in Study 2 was positively correlated with ampF-wavemax and ampF-wavemean (p<0.001, r= 0.717; p<0.001, r=0.786, respectively).
Conclusion: This study demonstrated that JM increased F-wave persistence and amplitude. Jendrassik maneuver may show its effect through motor neuron excitability.
{"title":"The effect of Jendrassik maneuver on the persistence of the peroneal nerve F-wave.","authors":"Halit Fidancı, İlker Öztürk, Şencan Buturak, Mehmet Yıldız, Zülfikar Arlier","doi":"10.5606/tftrd.2023.10931","DOIUrl":"https://doi.org/10.5606/tftrd.2023.10931","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated whether peroneal nerve F-wave persistence increased when the Jendrassik maneuver (JM) was performed, aiming to obtain information about the physiology of F-waves and JM.</p><p><strong>Patients and methods: </strong>Thirty healthy individuals (HIs; 17 females, 13 males; mean age: 33.6±8.2 years; range, 23-50 years) were included in the prospective experimental study conducted between June 15, 2021, and December 15, 2021. Nerve conduction studies of peroneal, superficial peroneal, posterior tibial, and sural nerves were performed in one extremity of each HI. The peroneal nerve F-wave study was performed at rest (Study 1), during JM (Study 2), and after JM (Study 3). F-wave persistence of the peroneal nerve, maximum F-wave amplitude (ampF-wave<sub>max</sub>), mean F-wave amplitude (ampF-wave<sub>mean</sub>), minimum F-wave latency, and the ratio of ampF-wave<sub>mean</sub> to maximum M amplitude (F/M ratio) were analyzed.</p><p><strong>Results: </strong>The mean peroneal nerve F-wave persistence in Study 1, Study 2, and Study 3 was 28.7±23.9%, 52.3±32.1%, and 34.7±29.0%, respectively. F-wave persistence in Study 2 was higher compared to Studies 1 and 3 (p<0.001 and p<0.001, respectively). Moreover, ampF-wave<sub>max</sub>, ampF-wave<sub>mean</sub>, and F/M ratio in Study 2 were higher than Studies 1 and 3 (p=0.026 and p=0.021 for ampF-wave<sub>mean</sub>; p=0.015 and p=0.003 for ampF-wave<sub>max</sub>; p=0.033 and p=0.015 for F/M ratio, respectively). F-wave persistence in Study 2 was positively correlated with ampF-wave<sub>max</sub> and ampF-wave<sub>mean</sub> (p<0.001, r= 0.717; p<0.001, r=0.786, respectively).</p><p><strong>Conclusion: </strong>This study demonstrated that JM increased F-wave persistence and amplitude. Jendrassik maneuver may show its effect through motor neuron excitability.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"309-316"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/8a/TurkJPhysMedRehab-69-309.PMC10478551.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10171080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aims to investigate the effect of the hot pack application on the morphology of healthy median and ulnar nerves.
Patients and methods: Between August 2021 and September 2022, a total of 54 healthy volunteers (17 males, 37 females; mean age: 31.9±9.4 years; range, 21 to 63 years) were included in the study. The cross-sectional area (CSA) and depth of the right median and ulnar nerve were measured using ultrasonography before and after 20-min hot pack application. The right median nerve CSA and depth from the level of the scaphoid bone (at the level of the carpal tunnel) and from the mid-forearm were also measured. The right ulnar nerve CSA and depth from the level of the hook of hamate and the mid-forearm were evaluated. The depth measurements between the skin and the outer hyperechoic border of the nerve were performed.
Results: After the hot pack application, there was an increase in both the median nerve CSA at the carpal tunnel (from 0.06±0.01 to 0.09±0.02 cm2 ) and forearm (from 0.06±0.02 to 0.09±0.02 cm2 ) levels (p<0.001) and the ulnar nerve CSA at the hook of hamate (from 0.04±0.03 to 0.06±0.01 cm2 ) and forearm (0.05±0.01 to 0.08±0.02 cm2 ) levels (p<0.001). No statistically significant difference was observed between the pre- and post-application depth measurements (p>0.05).
Conclusion: Our study results show that the hot pack application leads to acute swelling of the median and ulnar nerves. In future studies, the relationship between morphological changes in healthy and pathological nerves and electrodiagnostic findings should be investigated.
{"title":"Does hot pack application change the morphology of the median and ulnar nerves?","authors":"Fatima Yaman, Merve Akdeniz Leblebicier, Aysun Özlü, Emine Cihan, Dilan Bulut Özkaya","doi":"10.5606/tftrd.2023.11812","DOIUrl":"https://doi.org/10.5606/tftrd.2023.11812","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the effect of the hot pack application on the morphology of healthy median and ulnar nerves.</p><p><strong>Patients and methods: </strong>Between August 2021 and September 2022, a total of 54 healthy volunteers (17 males, 37 females; mean age: 31.9±9.4 years; range, 21 to 63 years) were included in the study. The cross-sectional area (CSA) and depth of the right median and ulnar nerve were measured using ultrasonography before and after 20-min hot pack application. The right median nerve CSA and depth from the level of the scaphoid bone (at the level of the carpal tunnel) and from the mid-forearm were also measured. The right ulnar nerve CSA and depth from the level of the hook of hamate and the mid-forearm were evaluated. The depth measurements between the skin and the outer hyperechoic border of the nerve were performed.</p><p><strong>Results: </strong>After the hot pack application, there was an increase in both the median nerve CSA at the carpal tunnel (from 0.06±0.01 to 0.09±0.02 cm<sup>2</sup> ) and forearm (from 0.06±0.02 to 0.09±0.02 cm<sup>2</sup> ) levels (p<0.001) and the ulnar nerve CSA at the hook of hamate (from 0.04±0.03 to 0.06±0.01 cm<sup>2</sup> ) and forearm (0.05±0.01 to 0.08±0.02 cm<sup>2</sup> ) levels (p<0.001). No statistically significant difference was observed between the pre- and post-application depth measurements (p>0.05).</p><p><strong>Conclusion: </strong>Our study results show that the hot pack application leads to acute swelling of the median and ulnar nerves. In future studies, the relationship between morphological changes in healthy and pathological nerves and electrodiagnostic findings should be investigated.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"344-349"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/8f/TurkJPhysMedRehab-69-344.PMC10478542.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10181360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.5606/tftrd.2023.12387
Pervin Demir, Ayşe Adile Küçükdeveci, Şehim Kutlay, Atilla Halil Elhan
Objectives: Various scales exist to assess different domains of functioning in knee osteoarthritis (OA). This study aimed to explore whether it is possible to develop a common metric (CM) from the frequently used scales to assess functioning in knee OA.
Patients and methods: The methodological study evaluated 411 patients (81 males, 330 females; mean age: 61.8±10.5 years; range, 41 to 88 years) with knee OA. Data from the Health Assessment Questionnaire, Oxford Knee Score, Medical Outcomes Study Short Form 36, Knee Injury and Osteoarthritis Outcome Score, Western Ontario and McMaster Universities Arthritis Index, and the Nottingham Health Profile were used, and the items focusing on self-care, mobility, and domestic activity domains based on the activities and participation component of the International Classification of Functioning, Disability, and Health were included. Concurrent calibration was performed to combine the items of the scales. The CM parameters were estimated using the Rasch measurement model. Reliability was assessed using the person separation index. The CM was utilized to generate a transformation table to convert the scale scores to each other based on the reference metric score.
Results: Each scale fitted the Rasch model. Item invariance was achieved for the CM (p=0.775). The CM had a person separation index of 0.827. Age, sex, and disease duration did not cause difference in item functions. The CM satisfied the assumptions of unidimensionality and local independence.
Conclusion: A reliable CM was created from the commonly used scales to measure functioning in individuals with knee OA. Thus, clinicians and researchers can refer to the transformation table to directly compare scores of those scales and use them interchangeably.
{"title":"Developing a common metric using current scales for assessing functioning in patients with knee osteoarthritis.","authors":"Pervin Demir, Ayşe Adile Küçükdeveci, Şehim Kutlay, Atilla Halil Elhan","doi":"10.5606/tftrd.2023.12387","DOIUrl":"https://doi.org/10.5606/tftrd.2023.12387","url":null,"abstract":"<p><strong>Objectives: </strong>Various scales exist to assess different domains of functioning in knee osteoarthritis (OA). This study aimed to explore whether it is possible to develop a common metric (CM) from the frequently used scales to assess functioning in knee OA.</p><p><strong>Patients and methods: </strong>The methodological study evaluated 411 patients (81 males, 330 females; mean age: 61.8±10.5 years; range, 41 to 88 years) with knee OA. Data from the Health Assessment Questionnaire, Oxford Knee Score, Medical Outcomes Study Short Form 36, Knee Injury and Osteoarthritis Outcome Score, Western Ontario and McMaster Universities Arthritis Index, and the Nottingham Health Profile were used, and the items focusing on self-care, mobility, and domestic activity domains based on the activities and participation component of the International Classification of Functioning, Disability, and Health were included. Concurrent calibration was performed to combine the items of the scales. The CM parameters were estimated using the Rasch measurement model. Reliability was assessed using the person separation index. The CM was utilized to generate a transformation table to convert the scale scores to each other based on the reference metric score.</p><p><strong>Results: </strong>Each scale fitted the Rasch model. Item invariance was achieved for the CM (p=0.775). The CM had a person separation index of 0.827. Age, sex, and disease duration did not cause difference in item functions. The CM satisfied the assumptions of unidimensionality and local independence.</p><p><strong>Conclusion: </strong>A reliable CM was created from the commonly used scales to measure functioning in individuals with knee OA. Thus, clinicians and researchers can refer to the transformation table to directly compare scores of those scales and use them interchangeably.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"69 3","pages":"350-365"},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/8c/TurkJPhysMedRehab-69-350.PMC10478544.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10177859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-16DOI: 10.33696/rehabilitation.5.036
N. Eskandari, A. Andalib
Nahid Eskandari1, Alireza Andalib1,* 1Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran *Correspondence should be addressed to Alireza Andalib, andalib@med.mui.ac.ir Received date: June 11, 2023, Accepted date: July 14, 2023 Citation: Eskandari N, Andalib A. The Interplay of Interferon-Beta, Cobalamin, and MicroRNA Regulation in Multiple Sclerosis Therapy. J Phys Med Rehabil. 2023;5(1):26-27.
{"title":"The Interplay of Interferon-Beta, Cobalamin, and MicroRNA Regulation in Multiple Sclerosis Therapy","authors":"N. Eskandari, A. Andalib","doi":"10.33696/rehabilitation.5.036","DOIUrl":"https://doi.org/10.33696/rehabilitation.5.036","url":null,"abstract":"Nahid Eskandari1, Alireza Andalib1,* 1Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran *Correspondence should be addressed to Alireza Andalib, andalib@med.mui.ac.ir Received date: June 11, 2023, Accepted date: July 14, 2023 Citation: Eskandari N, Andalib A. The Interplay of Interferon-Beta, Cobalamin, and MicroRNA Regulation in Multiple Sclerosis Therapy. J Phys Med Rehabil. 2023;5(1):26-27.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"122 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73304958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-18DOI: 10.33696/rehabilitation.5.033
Low Yi Xian, A. G. W. Goh, S. Quek
Ulnar impingement syndrome is caused by a shortened ulna impinging on the distal radius and causing a painful, disabling pseudoarthrosis. Vaughan-Jackson syndrome is characterized by a disruption of the digital extensor tendons, beginning on the ulnar side with the extensor digiti minimi (EDM) and extensor digitorum communis (EDC) tendon of the small finger. While ulnar impingement and Vaughan-Jackson syndrome are not uncommon, it is rare to observe the two conditions occurring simultaneously. We report a unique case of ulnar impingement syndrome presenting with Vaughan-Jackson syndrome, revealing that the degenerative changes from ulnar impingement syndrome can cause attrition rupture of the EDM and EDC tendon of the little finger. This entails increased clinical significance of ulnar impingement, because in addition to its potential to cause debilitating pain, there is also consequence of functional deficits if extensor tendon rupture were to occur due to progressive degenerative changes. The surgical management of distal radioulnar joint (DRUJ) arthritis arising from ulnar impingement may include various intra-operative techniques to prevent post-operative extensor tendon rupture.
{"title":"Extensor Tendon Rupture in Ulnar Impingement Syndrome: A Case Report","authors":"Low Yi Xian, A. G. W. Goh, S. Quek","doi":"10.33696/rehabilitation.5.033","DOIUrl":"https://doi.org/10.33696/rehabilitation.5.033","url":null,"abstract":"Ulnar impingement syndrome is caused by a shortened ulna impinging on the distal radius and causing a painful, disabling pseudoarthrosis. Vaughan-Jackson syndrome is characterized by a disruption of the digital extensor tendons, beginning on the ulnar side with the extensor digiti minimi (EDM) and extensor digitorum communis (EDC) tendon of the small finger. While ulnar impingement and Vaughan-Jackson syndrome are not uncommon, it is rare to observe the two conditions occurring simultaneously. We report a unique case of ulnar impingement syndrome presenting with Vaughan-Jackson syndrome, revealing that the degenerative changes from ulnar impingement syndrome can cause attrition rupture of the EDM and EDC tendon of the little finger. This entails increased clinical significance of ulnar impingement, because in addition to its potential to cause debilitating pain, there is also consequence of functional deficits if extensor tendon rupture were to occur due to progressive degenerative changes. The surgical management of distal radioulnar joint (DRUJ) arthritis arising from ulnar impingement may include various intra-operative techniques to prevent post-operative extensor tendon rupture.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"15 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86123009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-18DOI: 10.33696/rehabilitation.5.034
Émélie Séguin, Marc Doumit
Loss of mobility and independence directly affects the quality of life of many vulnerable individuals. In order to address this, researchers have been developing wearable walking assist exoskeletons to aid users with their daily activities. While this technology has advanced tremendously in the past decade, current exoskeletons are yet to be ergonomic, causing discomfort and injuries to the user, leading to early device rejection. This research intends to assess the kinematic and kinetic compatibility of a novel knee joint suitable for exoskeletons. The proposed knee design can be adapted to accommodate a kinematic offset and optimize force delivery. This is achieved by ensuring that the mechanical and biological joint rotation axes are aligned and that the moment arm can be varied to mimic the mechanical characteristics of a biological knee. Model simulations and mechanical testing of fabricated prototypes were achieved to analyze and validate the design. Results confirmed the compatibility of the design, which demonstrated kinematic absolute error values of 1.68 and 0.32 mm for the offset and aligned joints, respectively. It was shown that the moment arm can be varied throughout flexion, allowing future iterations to achieve optimal and effective moment transfer.
{"title":"Kinematic and Kinetic Assessment of a Novel Polycentric Knee Joint for Powered Walking Assist Exoskeletons","authors":"Émélie Séguin, Marc Doumit","doi":"10.33696/rehabilitation.5.034","DOIUrl":"https://doi.org/10.33696/rehabilitation.5.034","url":null,"abstract":"Loss of mobility and independence directly affects the quality of life of many vulnerable individuals. In order to address this, researchers have been developing wearable walking assist exoskeletons to aid users with their daily activities. While this technology has advanced tremendously in the past decade, current exoskeletons are yet to be ergonomic, causing discomfort and injuries to the user, leading to early device rejection. This research intends to assess the kinematic and kinetic compatibility of a novel knee joint suitable for exoskeletons. The proposed knee design can be adapted to accommodate a kinematic offset and optimize force delivery. This is achieved by ensuring that the mechanical and biological joint rotation axes are aligned and that the moment arm can be varied to mimic the mechanical characteristics of a biological knee. Model simulations and mechanical testing of fabricated prototypes were achieved to analyze and validate the design. Results confirmed the compatibility of the design, which demonstrated kinematic absolute error values of 1.68 and 0.32 mm for the offset and aligned joints, respectively. It was shown that the moment arm can be varied throughout flexion, allowing future iterations to achieve optimal and effective moment transfer.","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"14 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78297513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The aim of this study was to evaluate the results of the construct validity of the Comprehensive International Classification of Functioning, Disability and Health (ICF) Core Set for Multiple Sclerosis (MS) and to identify the impact of MS on specific health domains according to the ICF categories in Turkish individuals.
Patients and methods: Between December 2011 and December 2012, a total of 150 individuals with MS (69 males, 81 females; mean age: 39.8±8.0 years; range, 19 to 52 years) who were diagnosed by a neurologist at least six months previously were included. The Comprehensive ICF Core Set for MS was used to assess functioning, disability, and environmental factors in all participants. The Spearman correlation coefficient was used to determine construct validity of the ICF Core Set between the ICF components and disease-specific and general measurements.
Results: The most frequently coded impairments in the body functions component were b280 sensation of pain, b134 sleep functions, b1301 motivations, and b740 muscle endurance functions. The most frequently coded impairments in the body structures component were s110 structure of brain, s120 spinal cord and related structures and s750 structure of lower extremity. A significant problem was documented in 47 of the 53 categories of the activities and participation. Of the 38 categories in the environmental factors, 23 were identified as a facilitator, while 12 categories were identified as a barrier. All body function, structure, activities and participation and environmental factors categories showed a significant correlation with disease-specific and generic measures.
Conclusion: Based on these results, the ICF Core Set may help to determine major facilitators or barriers to functioning and disability and a targeted rehabilitation approach in patients with MS.
{"title":"Validation of the Comprehensive ICF Core Set for Multiple Sclerosis: A Turkish clinical perspective.","authors":"Özge Ortabozkoyun, Bilge Kesikburun, Belma Füsun Köseoğlu, Ufuk Ergün, Levent İnan","doi":"10.5606/tftrd.2023.11907","DOIUrl":"10.5606/tftrd.2023.11907","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate the results of the construct validity of the Comprehensive International Classification of Functioning, Disability and Health (ICF) Core Set for Multiple Sclerosis (MS) and to identify the impact of MS on specific health domains according to the ICF categories in Turkish individuals.</p><p><strong>Patients and methods: </strong>Between December 2011 and December 2012, a total of 150 individuals with MS (69 males, 81 females; mean age: 39.8±8.0 years; range, 19 to 52 years) who were diagnosed by a neurologist at least six months previously were included. The Comprehensive ICF Core Set for MS was used to assess functioning, disability, and environmental factors in all participants. The Spearman correlation coefficient was used to determine construct validity of the ICF Core Set between the ICF components and disease-specific and general measurements.</p><p><strong>Results: </strong>The most frequently coded impairments in the body functions component were b280 sensation of pain, b134 sleep functions, b1301 motivations, and b740 muscle endurance functions. The most frequently coded impairments in the body structures component were s110 structure of brain, s120 spinal cord and related structures and s750 structure of lower extremity. A significant problem was documented in 47 of the 53 categories of the activities and participation. Of the 38 categories in the environmental factors, 23 were identified as a facilitator, while 12 categories were identified as a barrier. All body function, structure, activities and participation and environmental factors categories showed a significant correlation with disease-specific and generic measures.</p><p><strong>Conclusion: </strong>Based on these results, the ICF Core Set may help to determine major facilitators or barriers to functioning and disability and a targeted rehabilitation approach in patients with MS.</p>","PeriodicalId":56043,"journal":{"name":"Turkish Journal of Physical Medicine and Rehabilitation","volume":"70 1","pages":"17-29"},"PeriodicalIF":1.3,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10966755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}