Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/61995.2918
A Venkata Ranga Swamy, Jandhyam Manikantan, D Raja Reddy, Mutyasri Pedapathnapu, K Sitha Ramaiah, A Bhagavan
Introduction: Tadalafil and tamsulosin have both been approved for use in the management of Lower Urinary Tract Symptoms (LUTS). Limited studies have shown the efficacy of tadalafil in terms of maximum urinary output flow (Qmax) and post-void residual (PVR). Aim: To compare the efficacy of tadalafil 5 mg and tamsulosin 0.4 mg in patients with Benign Prostatic Hyperplasia (BPH). Materials and Methods: A prospective, open-label, Randomised clinical study was conducted in the Department of Urology at Kurnool Medical College, Kurnool, Andhra Pradesh, India. The study duration was one year and five months, from February 2015 to July 2016. A total of 83 patients clinically diagnosed with BPH were included, but 23 patients were excluded from the analysis due to lost follow-up. The remaining 60 patients were randomly assigned to two groups: one receiving tadalafil 5 mg (n=30) and the other receiving tamsulosin 0.4 mg (n=30) for 12 weeks. Demographic characteristics, total International Prostate Symptom Score (IPSS), individual IPSS, Quality of Life (QoL) score, Qmax, PVR, and differences in symptoms were analysed. Data were analysed using the Wilcoxon signed-rank test and Mann-Whitney U test. A p-value<0.05 was considered statistically significant. Results: The mean age for group I (tadalafil 5 mg) and Group II (tamsulosin 0.4 mg) was 62.7 and 61.0 years, respectively (p=0.147). Patients who received tadalafil showed significantly higher efficacy in all measures from baseline to 12 weeks, including increased Qmax (12.0 mL/sec vs 15.1 mL/sec), reduced QoL scores (4.2 vs 3.7), and PVR (26.5 mL vs 15.8 mL), compared to tamsulosin where the increase in Qmax was 11.6 mL/sec vs 13.6 mL/sec, reduction in QoL scores was 4.1 vs 2.4, and PVR was 24.0 mL vs 16.2 mL, between baseline and 12 weeks. Conclusion: Tadalafil 5 mg is a recent drug option available for the treatment of LUTS-BPH. The efficacy and safety of tadalafil 5 mg and tamsulosin 0.4 mg are comparable.
他达拉非和坦索罗辛都已被批准用于治疗下尿路症状(LUTS)。有限的研究表明他达拉非在最大尿输出流量(Qmax)和尿后残留(PVR)方面的有效性。目的:比较他达拉非5mg与坦索罗辛0.4 mg治疗良性前列腺增生(BPH)的疗效。材料和方法:在印度安得拉邦Kurnool医学院泌尿科进行了一项前瞻性、开放标签、随机临床研究。研究时间为一年零五个月，从2015年2月至2016年7月。共纳入83例临床诊断为BPH的患者，但有23例患者因失去随访而被排除在分析之外。其余60例患者随机分为两组:一组接受他达拉非5 mg (n=30)，另一组接受坦索罗辛0.4 mg (n=30)，疗程12周。分析人口学特征、国际前列腺症状评分(IPSS)、个体IPSS、生活质量(QoL)评分、Qmax、PVR和症状差异。数据分析采用Wilcoxon符号秩检验和Mann-Whitney U检验。p值0.05被认为具有统计学意义。结果:I组(他达拉非5 mg)和II组(坦索罗辛0.4 mg)患者的平均年龄分别为62.7岁和61.0岁(p=0.147)。从基线到12周，接受他达拉非的患者在所有测量中都显示出显着更高的疗效，包括Qmax增加(12.0 mL/sec vs 15.1 mL/sec)， QoL评分降低(4.2 vs 3.7)和PVR (26.5 mL vs 15.8 mL)，与坦索罗辛相比，Qmax增加11.6 mL/sec vs 13.6 mL/sec, QoL评分降低4.1 vs 2.4, PVR为24.0 mL vs 16.2 mL，基线和12周。结论:他达拉非5mg是治疗LUTS-BPH的最新药物选择。他达拉非5mg与坦索罗辛0.4 mg的疗效和安全性相当。
{"title":"Tadalafil vs Tamsulosin for the Management of Lower Urinary Tract Symptoms in Men with Benign Prostatic Hyperplasia: A Randomised Clinical Trial","authors":"A Venkata Ranga Swamy, Jandhyam Manikantan, D Raja Reddy, Mutyasri Pedapathnapu, K Sitha Ramaiah, A Bhagavan","doi":"10.7860/ijars/2023/61995.2918","DOIUrl":"https://doi.org/10.7860/ijars/2023/61995.2918","url":null,"abstract":"Introduction: Tadalafil and tamsulosin have both been approved for use in the management of Lower Urinary Tract Symptoms (LUTS). Limited studies have shown the efficacy of tadalafil in terms of maximum urinary output flow (Qmax) and post-void residual (PVR). Aim: To compare the efficacy of tadalafil 5 mg and tamsulosin 0.4 mg in patients with Benign Prostatic Hyperplasia (BPH). Materials and Methods: A prospective, open-label, Randomised clinical study was conducted in the Department of Urology at Kurnool Medical College, Kurnool, Andhra Pradesh, India. The study duration was one year and five months, from February 2015 to July 2016. A total of 83 patients clinically diagnosed with BPH were included, but 23 patients were excluded from the analysis due to lost follow-up. The remaining 60 patients were randomly assigned to two groups: one receiving tadalafil 5 mg (n=30) and the other receiving tamsulosin 0.4 mg (n=30) for 12 weeks. Demographic characteristics, total International Prostate Symptom Score (IPSS), individual IPSS, Quality of Life (QoL) score, Qmax, PVR, and differences in symptoms were analysed. Data were analysed using the Wilcoxon signed-rank test and Mann-Whitney U test. A p-value<0.05 was considered statistically significant. Results: The mean age for group I (tadalafil 5 mg) and Group II (tamsulosin 0.4 mg) was 62.7 and 61.0 years, respectively (p=0.147). Patients who received tadalafil showed significantly higher efficacy in all measures from baseline to 12 weeks, including increased Qmax (12.0 mL/sec vs 15.1 mL/sec), reduced QoL scores (4.2 vs 3.7), and PVR (26.5 mL vs 15.8 mL), compared to tamsulosin where the increase in Qmax was 11.6 mL/sec vs 13.6 mL/sec, reduction in QoL scores was 4.1 vs 2.4, and PVR was 24.0 mL vs 16.2 mL, between baseline and 12 weeks. Conclusion: Tadalafil 5 mg is a recent drug option available for the treatment of LUTS-BPH. The efficacy and safety of tadalafil 5 mg and tamsulosin 0.4 mg are comparable.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135446397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/61164.2894
Ankit Vyas, Alhad Mulkalwar, K. Singh, S. Patwardhan
Intrauterine Contraceptive Devices (IUCD) are known to be associated with many complications; however, uterine perforation with migration into adjacent soft tissue is rarely observed. The authors report a rare case of a 31-year-old full-term pregnant female who presented in labour and was posted for a Lower Segment Caesarean Section (LSCS) in view of a history of LSCS. Dense adhesions were noticed between the posterior wall of urinary bladder and uterus. A foreign body was also palpable in the bladder. The limb of an IUCD (Copper T) was seen through a rent in the bladder wall, via which it was removed in its entirety. As asymptomatic cases missed by routine scans can occur, Magnetic Resonance Imaging (MRI) may have a role to play in dubious cases of pregnancy having a history of IUD insertion which wasn’t removed.
{"title":"Asymptomatic Intravesical Migration of an Intrauterine Device Detected during Delivery","authors":"Ankit Vyas, Alhad Mulkalwar, K. Singh, S. Patwardhan","doi":"10.7860/ijars/2023/61164.2894","DOIUrl":"https://doi.org/10.7860/ijars/2023/61164.2894","url":null,"abstract":"Intrauterine Contraceptive Devices (IUCD) are known to be associated with many complications; however, uterine perforation with migration into adjacent soft tissue is rarely observed. The authors report a rare case of a 31-year-old full-term pregnant female who presented in labour and was posted for a Lower Segment Caesarean Section (LSCS) in view of a history of LSCS. Dense adhesions were noticed between the posterior wall of urinary bladder and uterus. A foreign body was also palpable in the bladder. The limb of an IUCD (Copper T) was seen through a rent in the bladder wall, via which it was removed in its entirety. As asymptomatic cases missed by routine scans can occur, Magnetic Resonance Imaging (MRI) may have a role to play in dubious cases of pregnancy having a history of IUD insertion which wasn’t removed.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71264071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/59856.2871
K. Kiran, A. Ramani, S. Math
Introduction: Surgical techniques in open appendicectomy has been evolving with most centers following simple ligation of appendix stump as the most preferred approach including the laparoscopic approach. Invagination of stump of the appendix is also practiced as a traditional approach. Aim: To compare and evaluate the outcomes and postoperative morbidity of simple ligation and invagination appendicectomy techniques. Materials and Methods: This was a prospective observational study conducted from October 2016 to July 2018 and included a total of 100 patients of acute appendicitis undergoing emergency open appendectomy surgery. The method of surgery of simple ligation and invagination appendectomy was allotted alternatively with 50 patients in each category. Both techniques of surgery were compared in terms of operating time, duration of hospital stay and postsurgical complications. Relevant data was collected and entered in Microsoft excel and p-value was calculated using Chi-square test. Results: A total of 100 patients were included with a mean age of 27 years. Both the groups with 50 patients each, were equivalent with age and gender distribution. It was observed that both the techniques had similar outcomes in respect to mean duration of surgery, duration of hospital stay and morbidities (p-value>0.05) with no statistically significant difference. The morbidity and the rate of postoperative complications were similar in both the groups. Conclusion: Appendicular stump management after appendectomy can be treated either by simple ligation or by invagination method, both techniques being equally effective and safe. Hence, it is surgeons preference to choose among the two techniques.
{"title":"Outcomes of Open Appendicectomy by Simple Ligation versus Invagination in Acute Appendicitis- A Prospective Observational Study","authors":"K. Kiran, A. Ramani, S. Math","doi":"10.7860/ijars/2023/59856.2871","DOIUrl":"https://doi.org/10.7860/ijars/2023/59856.2871","url":null,"abstract":"Introduction: Surgical techniques in open appendicectomy has been evolving with most centers following simple ligation of appendix stump as the most preferred approach including the laparoscopic approach. Invagination of stump of the appendix is also practiced as a traditional approach. Aim: To compare and evaluate the outcomes and postoperative morbidity of simple ligation and invagination appendicectomy techniques. Materials and Methods: This was a prospective observational study conducted from October 2016 to July 2018 and included a total of 100 patients of acute appendicitis undergoing emergency open appendectomy surgery. The method of surgery of simple ligation and invagination appendectomy was allotted alternatively with 50 patients in each category. Both techniques of surgery were compared in terms of operating time, duration of hospital stay and postsurgical complications. Relevant data was collected and entered in Microsoft excel and p-value was calculated using Chi-square test. Results: A total of 100 patients were included with a mean age of 27 years. Both the groups with 50 patients each, were equivalent with age and gender distribution. It was observed that both the techniques had similar outcomes in respect to mean duration of surgery, duration of hospital stay and morbidities (p-value>0.05) with no statistically significant difference. The morbidity and the rate of postoperative complications were similar in both the groups. Conclusion: Appendicular stump management after appendectomy can be treated either by simple ligation or by invagination method, both techniques being equally effective and safe. Hence, it is surgeons preference to choose among the two techniques.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71264421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/58542.2897
Dr.Y. Raghavendra, S. minz, G. Chaganti, Sravanthi Repalle, M. Krishnaiah
Introduction: Brachial Artery (BA) begins as a continuation of axillary artery at the distal border of teres major, it appears in the cubital fossa, where it ends at the level of the neck of radius by dividing into radial and ulnar arteries. Common Interosseous Artery (CIA) is the largest branch of Ulnar Artery (UA) and arises in the cubital fossa. The terminal branches of BA at elbow are clinically important since they are responsible for the arterial supply to the forearm and hand. These arteries may get damaged during fractures of the elbow. Aim: To know the variations in the terminal branches of the BA at elbow. Materials and Methods: The present cross-sectional cadaveric study was done on 40 upper limbs from embalmed adult human cadavers in the Department of Anatomy, Kamineni Institute of Medical Sciences, Narketpally, Telangana, India, from August 2017 to August 2019. Dissection of BA in arm and cubital fossa was carried out according to Cunningham’s manual of practical anatomy. The distance of division of BA into radial and UA and distance of origin of CIA from Inter Epicondylar Line (IEL) of humerus were noted. Results: In present study, 20 right-side specimens and 20 left- side specimens were obtained. Among 20 cadavers used, 16 were male cadavers and four were female cadavers. The mean distance (D1) of normal division of BA into the Radial Artery (RA) and UA at elbow was 2.8 cm below the imaginary line joining the medial and IEL. The mean distance (D2) of normal origin of CIA was 6.8 cm below the imaginary line joining the medial and lateral epicondyles of the humerus (IEL). CIA arising from the UA was present in 37 specimens (92.5%) and in the rest three specimens Anterior Interosseous Artery (AIA) and Posterior Interosseous Artery (PIA) arose directly from the UA. Conclusion: The present study has found variations in site of division of terminal branches of the BA at elbow in three specimens
{"title":"Variations in the Terminal Branches of Brachial Artery- A Cadaveric Cross-sectional Study","authors":"Dr.Y. Raghavendra, S. minz, G. Chaganti, Sravanthi Repalle, M. Krishnaiah","doi":"10.7860/ijars/2023/58542.2897","DOIUrl":"https://doi.org/10.7860/ijars/2023/58542.2897","url":null,"abstract":"Introduction: Brachial Artery (BA) begins as a continuation of axillary artery at the distal border of teres major, it appears in the cubital fossa, where it ends at the level of the neck of radius by dividing into radial and ulnar arteries. Common Interosseous Artery (CIA) is the largest branch of Ulnar Artery (UA) and arises in the cubital fossa. The terminal branches of BA at elbow are clinically important since they are responsible for the arterial supply to the forearm and hand. These arteries may get damaged during fractures of the elbow. Aim: To know the variations in the terminal branches of the BA at elbow. Materials and Methods: The present cross-sectional cadaveric study was done on 40 upper limbs from embalmed adult human cadavers in the Department of Anatomy, Kamineni Institute of Medical Sciences, Narketpally, Telangana, India, from August 2017 to August 2019. Dissection of BA in arm and cubital fossa was carried out according to Cunningham’s manual of practical anatomy. The distance of division of BA into radial and UA and distance of origin of CIA from Inter Epicondylar Line (IEL) of humerus were noted. Results: In present study, 20 right-side specimens and 20 left- side specimens were obtained. Among 20 cadavers used, 16 were male cadavers and four were female cadavers. The mean distance (D1) of normal division of BA into the Radial Artery (RA) and UA at elbow was 2.8 cm below the imaginary line joining the medial and IEL. The mean distance (D2) of normal origin of CIA was 6.8 cm below the imaginary line joining the medial and lateral epicondyles of the humerus (IEL). CIA arising from the UA was present in 37 specimens (92.5%) and in the rest three specimens Anterior Interosseous Artery (AIA) and Posterior Interosseous Artery (PIA) arose directly from the UA. Conclusion: The present study has found variations in site of division of terminal branches of the BA at elbow in three specimens","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71263577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/59115.2880
T. Chitrambalam, N. George, Sundeep Selvamuthukumaran, Lokesh G. Reddy, P. Christopher
Hydrocele of the canal of Nuck is a rare abnormality, developing in the protruded part of the parietal peritoneum within the inguinal canal in a female. It is homologous to the processus vaginalis in males and obliterates from the seventh month of gestation to one year of age. Failure of obliteration, results in Nuck hydrocele or herniation of intra-abdominal contents through the patent Canal of Nuck. These are usually detected and repaired in young girls within the first five years of life. Reports of Canal of Nuck hydrocele in adults are sparse. Most of these patients are misdiagnosed on clinical examination and correctly diagnosed intraoperatively during surgery for suspected ‘inguinal hernia’. Here, this case is about a 25-year-old female, who presented with swelling in the right groin for one month. Computed Tomography of the abdomen showed features suggestive of a hydrocele within the Canal of Nuck. She underwent laparoscopic hydrocelectomy and laparoscopic hernia repair via the transabdominal preperitoneal approach. This case report highlights the novel approach of laparoscopic management of this rare case.
{"title":"Hydrocele of Canal of Nuck In an Adult Female: A Case Report","authors":"T. Chitrambalam, N. George, Sundeep Selvamuthukumaran, Lokesh G. Reddy, P. Christopher","doi":"10.7860/ijars/2023/59115.2880","DOIUrl":"https://doi.org/10.7860/ijars/2023/59115.2880","url":null,"abstract":"Hydrocele of the canal of Nuck is a rare abnormality, developing in the protruded part of the parietal peritoneum within the inguinal canal in a female. It is homologous to the processus vaginalis in males and obliterates from the seventh month of gestation to one year of age. Failure of obliteration, results in Nuck hydrocele or herniation of intra-abdominal contents through the patent Canal of Nuck. These are usually detected and repaired in young girls within the first five years of life. Reports of Canal of Nuck hydrocele in adults are sparse. Most of these patients are misdiagnosed on clinical examination and correctly diagnosed intraoperatively during surgery for suspected ‘inguinal hernia’. Here, this case is about a 25-year-old female, who presented with swelling in the right groin for one month. Computed Tomography of the abdomen showed features suggestive of a hydrocele within the Canal of Nuck. She underwent laparoscopic hydrocelectomy and laparoscopic hernia repair via the transabdominal preperitoneal approach. This case report highlights the novel approach of laparoscopic management of this rare case.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71264008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/60510.2896
S. Gowsick, Lejeune Ramot Mahalakshmi, A. R. Urs
Fibroadenomas are the most common type of breast tumours diagnosed in young women. Fibroadenomas found in children and adolescents are termed as juvenile fibroadenomas of which giant fibroadenomas are rare account for 0.5%-2% of all fibroadenomas, that cause asymmetry of the breasts and are characterised by rapidly growing mass of more than 5 cm in greatest dimension, and/ or weight more than 500 gm, or replaces at least 80% of the breast. Both phyllodes tumour and giant fibroadenoma have similar clinical presentations. The current case is of 15-year-old female with a rapidly growing mass in the left breast with in a span of six month duration measuring 15×10 cm and was associated with dilated veins over it. The clinical diagnosis was suggestive of phyllodes tumour. Cytopathological and histopathological reports showed the evidence of juvenile giant fibroadenoma. Hence, the purpose of this report is to differentiate phyllodes tumour from juvenile giant fibroadenoma preoperatively to obtain the best cosmetic outcome for a developing breast lesion.
{"title":"A Case of Juvenile Giant Fibroadenoma of Breast: A Diagnostic Dilemma","authors":"S. Gowsick, Lejeune Ramot Mahalakshmi, A. R. Urs","doi":"10.7860/ijars/2023/60510.2896","DOIUrl":"https://doi.org/10.7860/ijars/2023/60510.2896","url":null,"abstract":"Fibroadenomas are the most common type of breast tumours diagnosed in young women. Fibroadenomas found in children and adolescents are termed as juvenile fibroadenomas of which giant fibroadenomas are rare account for 0.5%-2% of all fibroadenomas, that cause asymmetry of the breasts and are characterised by rapidly growing mass of more than 5 cm in greatest dimension, and/ or weight more than 500 gm, or replaces at least 80% of the breast. Both phyllodes tumour and giant fibroadenoma have similar clinical presentations. The current case is of 15-year-old female with a rapidly growing mass in the left breast with in a span of six month duration measuring 15×10 cm and was associated with dilated veins over it. The clinical diagnosis was suggestive of phyllodes tumour. Cytopathological and histopathological reports showed the evidence of juvenile giant fibroadenoma. Hence, the purpose of this report is to differentiate phyllodes tumour from juvenile giant fibroadenoma preoperatively to obtain the best cosmetic outcome for a developing breast lesion.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71264275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/59586.2906
Devasish Tarafdar, Maulik Jethva, C. Solanki, A. Trivedi
Introduction: The retroperitoneum is an important potential space in the human abdomen. Retroperitoneal (RP) tumours are extremely vast in position, size, rate of growth and in pathological types. They silently grow before giving rise to symptoms or become palpable. Radiology plays a unique role in sustaining the optimum information for the diagnosis of lesions of retroperitoneal space. Computed Tomography (CT) is generally more superior in the diagnosis of retroperitoneal neoplastic lesions in comparison to X-Ray or Ultrasonography (USG) but later are cost-effective and readily available. Aim: To describe the clinical spectrum of retroperitonial neoplastic lesions and also to evaluate the radiographic features of different retroperitoneal neoplastic lesions with various radiological modalities. Materials and Methods: This cross-sectional study was conducted on 50 patients from November 2019 to April 2021, in Department of Radiology of Pandit Deendayal Upadhyay Government Medical College and Civil Hospital, Rajkot, Gujarat. Each patient had undergone CT, USG and X-ray as indicated. Descriptive data was analysed and presented in terms of frequencies and percentages. Results: In this study among 50 patients, males (60%) were found to be affected more than the females (40%) with a male:female ratio of 1.5:1. The most common malignant RP neoplastic lesion was metastatic nodal masses and lymphoma. 41 (82%) of cases were malignant while 9 (18%) were benign neoplasms. The most common benign RP neoplastic lesion was teratoma. The most common presentation in patients with retroperitoneal lesions was pain and lump in the abdomen with abdominal distension. Most of the malignant lesions were of average size more than 10 cm. Conclusion: Most of the retroperitoneal neoplastic lesions were malignant and seen in males. CT, USG and X-ray are helpful in the characterisation and diagnosis of retroperitoneal neoplastic masses.
{"title":"Radiological Assessment of Retroperitoneal Neoplastic Lesions in a Tertiary Care Hospital, Rajkot, Gujarat, India: A Cross-sectional Study","authors":"Devasish Tarafdar, Maulik Jethva, C. Solanki, A. Trivedi","doi":"10.7860/ijars/2023/59586.2906","DOIUrl":"https://doi.org/10.7860/ijars/2023/59586.2906","url":null,"abstract":"Introduction: The retroperitoneum is an important potential space in the human abdomen. Retroperitoneal (RP) tumours are extremely vast in position, size, rate of growth and in pathological types. They silently grow before giving rise to symptoms or become palpable. Radiology plays a unique role in sustaining the optimum information for the diagnosis of lesions of retroperitoneal space. Computed Tomography (CT) is generally more superior in the diagnosis of retroperitoneal neoplastic lesions in comparison to X-Ray or Ultrasonography (USG) but later are cost-effective and readily available. Aim: To describe the clinical spectrum of retroperitonial neoplastic lesions and also to evaluate the radiographic features of different retroperitoneal neoplastic lesions with various radiological modalities. Materials and Methods: This cross-sectional study was conducted on 50 patients from November 2019 to April 2021, in Department of Radiology of Pandit Deendayal Upadhyay Government Medical College and Civil Hospital, Rajkot, Gujarat. Each patient had undergone CT, USG and X-ray as indicated. Descriptive data was analysed and presented in terms of frequencies and percentages. Results: In this study among 50 patients, males (60%) were found to be affected more than the females (40%) with a male:female ratio of 1.5:1. The most common malignant RP neoplastic lesion was metastatic nodal masses and lymphoma. 41 (82%) of cases were malignant while 9 (18%) were benign neoplasms. The most common benign RP neoplastic lesion was teratoma. The most common presentation in patients with retroperitoneal lesions was pain and lump in the abdomen with abdominal distension. Most of the malignant lesions were of average size more than 10 cm. Conclusion: Most of the retroperitoneal neoplastic lesions were malignant and seen in males. CT, USG and X-ray are helpful in the characterisation and diagnosis of retroperitoneal neoplastic masses.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71264496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/63227.2895
H. Gulati, Kamaljeet Kaur, J. Kaur, A. Wadhwa, Mamta Sharma
Introduction: In the current scenario, clinicians are constantly subjected to high workload coupled with enormous amount of stress which can lead to both derangement of sleep and accumulation of body fat. Since they are the central pillar of healthcare industry, the health of doctors themselves is an extremely important factor in pursuit of a healthy and disease free society. Aim: To determine the effect of Body Mass Index (BMI) on quality of sleep in clinicians and to establish a relation between obesity and sleep pattern of clinicians. Materials and Methods: The present descriptive study was conducted on 400 doctors working in Outpatient Department (OPD) clinics of various departments at Punjab Institute of Medical Sciences, Jalandhar and OPDs of NIMS Hospital, Jaipur, India, from July 2019 to June 2021. BMI was calculated as ratio of weight (kg) to the square of height (m). Sleep quality was assessed by Pittsburgh Sleep Quality Index (PSQI) questionnaire as a Global Pittsburgh Sleep Quality Index. BMI and sleep quality were checked for inter-relationship using various statistical methods like Chi- square test, Analysis of Variance (ANOVA), student t-test and Pearson’s correlation. Results: In the present study, 200 were males and 200 were females. Most of the participants were in the age group of 41- 50 years. A 51.4% of participants with BMI >25 kg/m2 had poor sleep quality which was significantly higher when compared with participants with BMI <25 kg/m2 (33.5%). Sleep quality had no significant bearing with gender. Further, it was found that surgical specialists had poorer sleep when compared with their medical counterparts. Conclusion: The results of the present study showed a significant association and linear correlation between sleep quality and overweight/obesity status. This information serves as an awareness and warning signal for the clinicians to safeguard their own health.
{"title":"Correlation Between Body Mass Index and Sleep Quality among Indian Doctors: A Descriptive Study","authors":"H. Gulati, Kamaljeet Kaur, J. Kaur, A. Wadhwa, Mamta Sharma","doi":"10.7860/ijars/2023/63227.2895","DOIUrl":"https://doi.org/10.7860/ijars/2023/63227.2895","url":null,"abstract":"Introduction: In the current scenario, clinicians are constantly subjected to high workload coupled with enormous amount of stress which can lead to both derangement of sleep and accumulation of body fat. Since they are the central pillar of healthcare industry, the health of doctors themselves is an extremely important factor in pursuit of a healthy and disease free society. Aim: To determine the effect of Body Mass Index (BMI) on quality of sleep in clinicians and to establish a relation between obesity and sleep pattern of clinicians. Materials and Methods: The present descriptive study was conducted on 400 doctors working in Outpatient Department (OPD) clinics of various departments at Punjab Institute of Medical Sciences, Jalandhar and OPDs of NIMS Hospital, Jaipur, India, from July 2019 to June 2021. BMI was calculated as ratio of weight (kg) to the square of height (m). Sleep quality was assessed by Pittsburgh Sleep Quality Index (PSQI) questionnaire as a Global Pittsburgh Sleep Quality Index. BMI and sleep quality were checked for inter-relationship using various statistical methods like Chi- square test, Analysis of Variance (ANOVA), student t-test and Pearson’s correlation. Results: In the present study, 200 were males and 200 were females. Most of the participants were in the age group of 41- 50 years. A 51.4% of participants with BMI >25 kg/m2 had poor sleep quality which was significantly higher when compared with participants with BMI <25 kg/m2 (33.5%). Sleep quality had no significant bearing with gender. Further, it was found that surgical specialists had poorer sleep when compared with their medical counterparts. Conclusion: The results of the present study showed a significant association and linear correlation between sleep quality and overweight/obesity status. This information serves as an awareness and warning signal for the clinicians to safeguard their own health.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71264999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/57005.2864
Sudhir Singh, Rajat D Maheshwari, Anupam Surendran, A. Sharath
Introduction: Head injury is one of the most common outcomes of any kind of trauma becoming the major cause of morbidity and mortality worldwide. The critical element in the treatment of patients with severe head injuries is to prevent the progression of the condition and secondary insult to brain cells. Various protocols are followed for the treatment of severe head injury starting from conservative medical management to surgical approaches like DC/hemicraniectomy (DC). The DC is a surgical method of removal of part of skull bone so that the brain parenchyma gets space to expand and the Intracranial Pressure (ICP) can get reduced. There are various factors that contribute to the outcome of DC. Aim: To determine the various factors that affect the outcome of DC/hemicraniectomy. Materials and Methods: A retrospective descriptive study was conducted in the Institute of Gandhi Medical College and associated Hamidia hospital, Madhya Pradesh, India from May 2017 to April 2021. Hundred patients with moderate to severe head injury who underwent primary DC were included in this study. The variables such as age, preoperative GCS, the timing of surgery, preoperative pupillary reaction, and MidLine Shift (MLS) were compared in terms of survival/death and favourable/ unfavourable outcomes using the chi-square test. Results: The mean age of participants was 45±14 years. Statistical analysis showed significant results for the variables like age, preoperative the Glasgow Coma Scale (GCS), timing of the surgery, pupillary reaction at presentation, and preoperative MLS in terms of survival/death and favourable/ unfavourable outcomes. Conclusion: Younger age group, better preoperative GCS, early surgery, reactive pupils at presentation, and less preoperative MLS have positive outcome benefits with the DC/ hemicraniectomy to reduce the raised ICP.
{"title":"Role of Decompressive Craniectomy/ Hemicraniectomy in the Management of Traumatic Brain Injury: A Retrospective Study","authors":"Sudhir Singh, Rajat D Maheshwari, Anupam Surendran, A. Sharath","doi":"10.7860/ijars/2023/57005.2864","DOIUrl":"https://doi.org/10.7860/ijars/2023/57005.2864","url":null,"abstract":"Introduction: Head injury is one of the most common outcomes of any kind of trauma becoming the major cause of morbidity and mortality worldwide. The critical element in the treatment of patients with severe head injuries is to prevent the progression of the condition and secondary insult to brain cells. Various protocols are followed for the treatment of severe head injury starting from conservative medical management to surgical approaches like DC/hemicraniectomy (DC). The DC is a surgical method of removal of part of skull bone so that the brain parenchyma gets space to expand and the Intracranial Pressure (ICP) can get reduced. There are various factors that contribute to the outcome of DC. Aim: To determine the various factors that affect the outcome of DC/hemicraniectomy. Materials and Methods: A retrospective descriptive study was conducted in the Institute of Gandhi Medical College and associated Hamidia hospital, Madhya Pradesh, India from May 2017 to April 2021. Hundred patients with moderate to severe head injury who underwent primary DC were included in this study. The variables such as age, preoperative GCS, the timing of surgery, preoperative pupillary reaction, and MidLine Shift (MLS) were compared in terms of survival/death and favourable/ unfavourable outcomes using the chi-square test. Results: The mean age of participants was 45±14 years. Statistical analysis showed significant results for the variables like age, preoperative the Glasgow Coma Scale (GCS), timing of the surgery, pupillary reaction at presentation, and preoperative MLS in terms of survival/death and favourable/ unfavourable outcomes. Conclusion: Younger age group, better preoperative GCS, early surgery, reactive pupils at presentation, and less preoperative MLS have positive outcome benefits with the DC/ hemicraniectomy to reduce the raised ICP.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71263692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.7860/ijars/2023/60683.2916
Roli Joshi, Pankaj Singh, Shalini Srivastava
Introduction: The thyroid gland regulates the basal metabolic rate, somatic growth, and physical growth. The thyroid gland plays a major role in the normal growth of a foetus during the prenatal period. There are few literatures on foetal thyroid gland. Aim: To study the various morphometric and histological changes during intrauterine life in both gender of human foetuses. Materials and Methods: This cross-sectional study was carried out in the Department of Obstetrics and Gynaecology, Dr. Sushila Tiwari Hospital Government Medical College, Haldwani (UK) and Saraswati Medical College, Unnao in the period of August 2015-2022. Government Medical College, Haldwani for duration of three years on medically terminated 70 foetus of both sexes of known gestational age ranging from 10 to 40 weeks. These foetuses were divided among three groups as group 1 (10-20 weeks), group 2 (21-30 weeks), group 3 (31- 40 week). Midline dissection of neck was done to expose the thyroid gland. Morphometric parameters like length, width, and thickness of each lobe and the isthmus were measured by digital Vernier caliper, weight was also taken by digital weighing machine, then tissue processing was done and paraffin blocks were prepared. All sections were stained with Haematoxylin and Eosin stain (H&E) and studied under the microscope aided camera. By using Analysis of Variance (ANOVA) test and Independent sample test (t-test) comparison among different age groups and gender has been done. Results: There was a significant increase in foetal thyroid weight, length and widths of the right and left lobes, and length of the isthmus with increase in gestational age, while no significant relation was found between male and female foetuses of measured morphometric parameter. The histological features revealed that development of thyroid gland starts earlier and thin capsule was seen at 12 week and it became thicker and more vascular till 35 weeks. Follicles started to form at 14 week and matured follicle were seen at the age of 24 weeks, at 25th week, the lining epithelium of follicles was low columnar to cuboidal, colloid material was seen almost in every follicle. C cells were found at 22 weeks. At the 36 weeks, the follicles were seen spherical and reached to maturity level. Conclusion: As the gestational age increases, the morphometric parameters must increase, if not so, it means the growth of gland is hampered. The knowledge of the growth and differentiation of foetal thyroid will be helpful for clinicians, to judge the thyroid structure prenatally.
简介:甲状腺调节基础代谢率、躯体生长和体格生长。在产前期间，甲状腺在胎儿的正常生长中起着重要作用。关于胎儿甲状腺的文献很少。目的:研究人类两性胎儿在宫内生活中的各种形态和组织学变化。材料与方法:本横断面研究于2015-2022年8月在英国Haldwani市Sushila Tiwari医院政府医学院妇产科和Unnao市Saraswati医学院进行。在哈尔德瓦尼政府医学院进行为期三年的医学终止手术，已知胎龄在10至40周的70名男女胎儿均有。将胎儿分为3组:1组(10 ~ 20周)、2组(21 ~ 30周)、3组(31 ~ 40周)。行颈部中线剥离，显露甲状腺。采用数字游标卡尺测量各叶及峡部的长、宽、厚等形态学参数，并采用数字称重机称重，然后进行组织处理，制作石蜡块。所有切片均采用Haematoxylin and Eosin染色(H&E)，在显微镜辅助相机下观察。采用方差分析(ANOVA)检验和独立样本检验(t-检验)对不同年龄组和性别进行了比较。结果:随着胎龄的增加，胎儿甲状腺重量、左右叶长宽、峡部长度均显著增加，而所测形态计量参数男女胎儿间无显著相关性。组织学特征显示，甲状腺发育较早，12周时可见薄囊，到35周时变厚，血管增多。14周时卵泡开始形成，24周时卵泡成熟，25周时卵泡内壁上皮呈低柱状至立方状，几乎每个卵泡均可见胶体物质。22周时发现C细胞。36周时，卵泡呈球形，达到成熟水平。结论:随着胎龄的增加，形态学参数必然增加，否则腺体发育受到阻碍。了解胎儿甲状腺的生长分化情况，有助于临床医生对胎儿甲状腺结构的判断。
{"title":"Morphometry and Histology of Thyroid Gland in Developing Human Foetuses: A Cross-sectional Study","authors":"Roli Joshi, Pankaj Singh, Shalini Srivastava","doi":"10.7860/ijars/2023/60683.2916","DOIUrl":"https://doi.org/10.7860/ijars/2023/60683.2916","url":null,"abstract":"Introduction: The thyroid gland regulates the basal metabolic rate, somatic growth, and physical growth. The thyroid gland plays a major role in the normal growth of a foetus during the prenatal period. There are few literatures on foetal thyroid gland. Aim: To study the various morphometric and histological changes during intrauterine life in both gender of human foetuses. Materials and Methods: This cross-sectional study was carried out in the Department of Obstetrics and Gynaecology, Dr. Sushila Tiwari Hospital Government Medical College, Haldwani (UK) and Saraswati Medical College, Unnao in the period of August 2015-2022. Government Medical College, Haldwani for duration of three years on medically terminated 70 foetus of both sexes of known gestational age ranging from 10 to 40 weeks. These foetuses were divided among three groups as group 1 (10-20 weeks), group 2 (21-30 weeks), group 3 (31- 40 week). Midline dissection of neck was done to expose the thyroid gland. Morphometric parameters like length, width, and thickness of each lobe and the isthmus were measured by digital Vernier caliper, weight was also taken by digital weighing machine, then tissue processing was done and paraffin blocks were prepared. All sections were stained with Haematoxylin and Eosin stain (H&E) and studied under the microscope aided camera. By using Analysis of Variance (ANOVA) test and Independent sample test (t-test) comparison among different age groups and gender has been done. Results: There was a significant increase in foetal thyroid weight, length and widths of the right and left lobes, and length of the isthmus with increase in gestational age, while no significant relation was found between male and female foetuses of measured morphometric parameter. The histological features revealed that development of thyroid gland starts earlier and thin capsule was seen at 12 week and it became thicker and more vascular till 35 weeks. Follicles started to form at 14 week and matured follicle were seen at the age of 24 weeks, at 25th week, the lining epithelium of follicles was low columnar to cuboidal, colloid material was seen almost in every follicle. C cells were found at 22 weeks. At the 36 weeks, the follicles were seen spherical and reached to maturity level. Conclusion: As the gestational age increases, the morphometric parameters must increase, if not so, it means the growth of gland is hampered. The knowledge of the growth and differentiation of foetal thyroid will be helpful for clinicians, to judge the thyroid structure prenatally.","PeriodicalId":56235,"journal":{"name":"International Journal of Anatomy Radiology and Surgery","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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