On June 24, 2017, a catastrophic landslide destroyed the village of Xinmo (Maoxian County, Sichuan, China). A 2.87 × 106 m3 rock mass in source area collapsed and entrained the surface soil layer along the run-out path. This disaster took eighty-three people’s lives and destroyed more than 103 houses. It is worth noting that rock fragmentation and grinding could expand the spreading area of danger zone in a landslide event. The Xinmo landslide provided a rare opportunity to infer the dynamic fragmentation and grinding of rock masses from the particle size and shape distribution in the entrainment and deposition area. A field investigation combined with an automatic image analysis system was conducted to study the characteristics of particle size and shape distribution along the debris channel. The image analysis of these field data showed that the median size (D50) of particles ranged from 0.41 to 27.71 m in the landslide area. Particle fractal dimension (D) obtained from the Number-size distribution ranged from 1.77 to 2.97 over the entire study area. Moreover, the evolution of D50 and D along the run-out path confirmed that the degree of cumulative rock fragmentation increased as the travel distance increased. Additionally, the particle roundness (R) ranged from 0.51 to 0.88 along the run-out path, which peaked twice during the motion of granular flow, once was in the entrainment area, and another was in the end of the deposition area. Rock scraping occurred in the entrainment area could increase the degree of rock grinding, and reshape coarse stones into smooth particles of large R values (larger roundness of particles could lead to longer spreading distance in a landslide event, due to the lower internal friction among particles). Based on analysis above, the rock scraping phenomena occurred between the source materials and entrainment materials were confirmed to influence the translation and spread of granular flows in landslides.