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Journal of Biological Inorganic Chemistry最新文献

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Role of the NHE1 exchanger in the antitumor effects of copper(II) complexes and phenanthroline derivatives. NHE1交换剂在铜(II)配合物和邻菲罗啉衍生物抗肿瘤作用中的作用。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-03-21 DOI: 10.1007/s00775-026-02142-3
K S Muñoz Garzón, V Martínez, V de Giusti, D Pérez Visñuk, M Villaverde, N Alvarez, G Facchin, A L Di Virgilio
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引用次数: 0
Lessons, connections, hypotheses and predictions from protein film electrochemistry. 蛋白质膜电化学的教训、联系、假设和预测。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-03-11 DOI: 10.1007/s00775-026-02136-1
Fraser A Armstrong
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引用次数: 0
A bioinorganic view on the potential chemical space of hydroxyphenylpyruvate dioxygenase-like (HPDL) enzymes. 羟基苯基丙酮酸双加氧酶样(HPDL)酶潜在化学空间的生物无机观点。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-03-10 DOI: 10.1007/s00775-026-02137-0
Niko S W Lindlar, Rolf Stucka, Sophie M Gutenthaler-Tietze, Jonathan Gutenthaler-Tietze, Jan Senderek, Lena J Daumann
{"title":"A bioinorganic view on the potential chemical space of hydroxyphenylpyruvate dioxygenase-like (HPDL) enzymes.","authors":"Niko S W Lindlar, Rolf Stucka, Sophie M Gutenthaler-Tietze, Jonathan Gutenthaler-Tietze, Jan Senderek, Lena J Daumann","doi":"10.1007/s00775-026-02137-0","DOIUrl":"https://doi.org/10.1007/s00775-026-02137-0","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical evaluation of two neutron structures of Mn superoxide dismutase with quantum refinement. 锰超氧化物歧化酶两种中子结构的量子精细评价。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-03-10 DOI: 10.1007/s00775-026-02140-5
Kristoffer J M Lundgren, Justin Bergmann, Esko Oksanen, Ulf Ryde
{"title":"Critical evaluation of two neutron structures of Mn superoxide dismutase with quantum refinement.","authors":"Kristoffer J M Lundgren, Justin Bergmann, Esko Oksanen, Ulf Ryde","doi":"10.1007/s00775-026-02140-5","DOIUrl":"https://doi.org/10.1007/s00775-026-02140-5","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging role of mitoNEET as mitochondrial sensor of hypoxia. mitoNEET作为线粒体缺氧传感器的新作用。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-03-09 DOI: 10.1007/s00775-026-02139-y
Nghi Thao Hoang, Kourosh Honarmand Ebrahimi
{"title":"Emerging role of mitoNEET as mitochondrial sensor of hypoxia.","authors":"Nghi Thao Hoang, Kourosh Honarmand Ebrahimi","doi":"10.1007/s00775-026-02139-y","DOIUrl":"https://doi.org/10.1007/s00775-026-02139-y","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of the interaction of ferrocenium salts with oligonucleotide by CVA, UV-visible and CD-spectroscopy. 二茂铁盐与寡核苷酸相互作用的CVA、uv -可见和cd光谱研究。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-03-09 DOI: 10.1007/s00775-026-02138-z
Ludmila N Telegina, Anastasia S Sipieva, Daria A Utepova, Alexey N Rodionov, Alexander A Simenel
{"title":"Study of the interaction of ferrocenium salts with oligonucleotide by CVA, UV-visible and CD-spectroscopy.","authors":"Ludmila N Telegina, Anastasia S Sipieva, Daria A Utepova, Alexey N Rodionov, Alexander A Simenel","doi":"10.1007/s00775-026-02138-z","DOIUrl":"https://doi.org/10.1007/s00775-026-02138-z","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and biological evaluation of a Rh(III) complex featuring Phosphonate-Modified bipyridine ligands. 以膦酸修饰联吡啶为配体的Rh(III)配合物的表征和生物学评价。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-02-11 DOI: 10.1007/s00775-026-02135-2
Thamilarasan Vijayan, Atifa Ashraf, Mohammad Azam, Jinheung Kim
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引用次数: 0
Meso-fluorinated cobalamins: insights into synthesis and redox properties. 中氟化钴胺素:对合成和氧化还原特性的见解。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-02-02 DOI: 10.1007/s00775-026-02133-4
Ilia A Dereven'kov, Vladimir S Osokin, Ilya A Khodov

Here, we present the first method of synthesis of cyano- (F-CNCbl) and aqua (F-H2OCbl) cobalamins, fluorinated at the C10 (meso) position of the corrin ring, and characterization of their redox properties. The reductive decyanation of F-CNCbl by glutathione and the reduction of F-H2OCbl to Co(II)-form (F-Cbl(II)) by glutathione or reduced nicotinamide adenine dinucleotide proceed more efficiently than the reactions involving unmodified complexes, which may facilitate their intracellular processing, especially in the case of patients with impaired metabolism of CblC-protein. The stability of the C-F bond in fluorinated Cbls displays remarkable stability upon F-Cbl(II) reduction to the Co(I) form is a remarkable finding, in stark contrast to the elimination of the Br atom in meso-brominated cobalamin is eliminated during this process.

在这里,我们提出了第一种合成氰基(F-CNCbl)和水(F-H2OCbl)钴胺素的方法,在corrin环的C10(中位)位置氟化,并表征了它们的氧化还原性质。谷胱甘肽对F-CNCbl的还原脱氰和谷胱甘肽或还原的烟酰胺腺嘌呤二核苷酸将F-H2OCbl还原为Co(II)-形式(F-Cbl(II))的反应比未修饰的复合物更有效,这可能有助于它们在细胞内的加工,特别是在cblc蛋白代谢受损的患者中。氟化钴胺中C-F键的稳定性在F-Cbl(II)还原为Co(I)形式时表现出显著的稳定性,这是一个显著的发现,与中溴化钴胺中Br原子的消除形成鲜明对比。
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引用次数: 0
A bezafibrate bearing Pt(IV) prodrug triggers ferroptosis via modulating lipid metabolism in lung cancer cells. 一种含有Pt(IV)前药的贝扎布酸盐通过调节肺癌细胞的脂质代谢引发铁下垂。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2026-01-21 DOI: 10.1007/s00775-025-02132-x
Neng Wan, Xuan-Lin Ren, Xiang-Yu Ma, Tao Zhu, Cheng-Zhi Xie, Jing-Yuan Xu, Xin Qiao
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引用次数: 0
Making connections: teaching and learning bioelectrochemistry. 建立联系:教与学生物电化学。
IF 2.7 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2025-12-24 DOI: 10.1007/s00775-025-02131-y
James P McEvoy

Advances in bioelectronic and renewable energy technologies make it important for undergraduate students to learn about bioelectrochemistry, and courses in the chemical and biological sciences provide opportunities for them to do so. This review surveys the ways in which bioelectrochemistry appears in these degree programs and evaluates effective educational practices in each case. Three key pedagogical challenges are identified: bioelectrochemical concepts are often abstract, the terminology is confusing and variable, and relevant material is fragmented across the curriculum. The review makes five recommendations to address these challenges. Educators are advised to (1) signpost connections across the curriculum to promote topic integration, (2) provide explicit guidance on terminology to pre-empt confusion, (3) use vivid biological examples to capture student attention and interest, (4) use active learning techniques to strengthen conceptual links, and (5) adopt published laboratory exercises that allow students to put bioelectrochemical theory into practice. In each case, examples are given to support implementation and enhance undergraduate student appreciation of the field.

生物电子和可再生能源技术的进步使得本科生学习生物电化学变得非常重要,化学和生物科学课程为他们提供了这样做的机会。这篇综述调查了生物电化学在这些学位课程中出现的方式,并评估了每种情况下有效的教育实践。我们确定了三个关键的教学挑战:生物电化学概念通常是抽象的,术语是令人困惑和多变的,相关材料在课程中是碎片化的。该审查提出了应对这些挑战的五项建议。建议教育工作者(1)在课程中建立联系以促进主题整合,(2)提供明确的术语指导以防止混淆,(3)使用生动的生物例子来吸引学生的注意力和兴趣,(4)使用主动学习技术来加强概念联系,(5)采用出版的实验室练习,让学生将生物电化学理论付诸实践。在每种情况下,给出的例子,以支持实施和提高本科学生对该领域的欣赏。
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引用次数: 0
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Journal of Biological Inorganic Chemistry
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