Pub Date : 2026-03-21DOI: 10.1007/s00775-026-02142-3
K S Muñoz Garzón, V Martínez, V de Giusti, D Pérez Visñuk, M Villaverde, N Alvarez, G Facchin, A L Di Virgilio
{"title":"Role of the NHE1 exchanger in the antitumor effects of copper(II) complexes and phenanthroline derivatives.","authors":"K S Muñoz Garzón, V Martínez, V de Giusti, D Pérez Visñuk, M Villaverde, N Alvarez, G Facchin, A L Di Virgilio","doi":"10.1007/s00775-026-02142-3","DOIUrl":"https://doi.org/10.1007/s00775-026-02142-3","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147493387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-11DOI: 10.1007/s00775-026-02136-1
Fraser A Armstrong
{"title":"Lessons, connections, hypotheses and predictions from protein film electrochemistry.","authors":"Fraser A Armstrong","doi":"10.1007/s00775-026-02136-1","DOIUrl":"https://doi.org/10.1007/s00775-026-02136-1","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-10DOI: 10.1007/s00775-026-02137-0
Niko S W Lindlar, Rolf Stucka, Sophie M Gutenthaler-Tietze, Jonathan Gutenthaler-Tietze, Jan Senderek, Lena J Daumann
{"title":"A bioinorganic view on the potential chemical space of hydroxyphenylpyruvate dioxygenase-like (HPDL) enzymes.","authors":"Niko S W Lindlar, Rolf Stucka, Sophie M Gutenthaler-Tietze, Jonathan Gutenthaler-Tietze, Jan Senderek, Lena J Daumann","doi":"10.1007/s00775-026-02137-0","DOIUrl":"https://doi.org/10.1007/s00775-026-02137-0","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-10DOI: 10.1007/s00775-026-02140-5
Kristoffer J M Lundgren, Justin Bergmann, Esko Oksanen, Ulf Ryde
{"title":"Critical evaluation of two neutron structures of Mn superoxide dismutase with quantum refinement.","authors":"Kristoffer J M Lundgren, Justin Bergmann, Esko Oksanen, Ulf Ryde","doi":"10.1007/s00775-026-02140-5","DOIUrl":"https://doi.org/10.1007/s00775-026-02140-5","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-09DOI: 10.1007/s00775-026-02139-y
Nghi Thao Hoang, Kourosh Honarmand Ebrahimi
{"title":"Emerging role of mitoNEET as mitochondrial sensor of hypoxia.","authors":"Nghi Thao Hoang, Kourosh Honarmand Ebrahimi","doi":"10.1007/s00775-026-02139-y","DOIUrl":"https://doi.org/10.1007/s00775-026-02139-y","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147389031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-09DOI: 10.1007/s00775-026-02138-z
Ludmila N Telegina, Anastasia S Sipieva, Daria A Utepova, Alexey N Rodionov, Alexander A Simenel
{"title":"Study of the interaction of ferrocenium salts with oligonucleotide by CVA, UV-visible and CD-spectroscopy.","authors":"Ludmila N Telegina, Anastasia S Sipieva, Daria A Utepova, Alexey N Rodionov, Alexander A Simenel","doi":"10.1007/s00775-026-02138-z","DOIUrl":"https://doi.org/10.1007/s00775-026-02138-z","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147388950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-11DOI: 10.1007/s00775-026-02135-2
Thamilarasan Vijayan, Atifa Ashraf, Mohammad Azam, Jinheung Kim
{"title":"Characterization and biological evaluation of a Rh(III) complex featuring Phosphonate-Modified bipyridine ligands.","authors":"Thamilarasan Vijayan, Atifa Ashraf, Mohammad Azam, Jinheung Kim","doi":"10.1007/s00775-026-02135-2","DOIUrl":"https://doi.org/10.1007/s00775-026-02135-2","url":null,"abstract":"","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146155479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1007/s00775-026-02133-4
Ilia A Dereven'kov, Vladimir S Osokin, Ilya A Khodov
Here, we present the first method of synthesis of cyano- (F-CNCbl) and aqua (F-H2OCbl) cobalamins, fluorinated at the C10 (meso) position of the corrin ring, and characterization of their redox properties. The reductive decyanation of F-CNCbl by glutathione and the reduction of F-H2OCbl to Co(II)-form (F-Cbl(II)) by glutathione or reduced nicotinamide adenine dinucleotide proceed more efficiently than the reactions involving unmodified complexes, which may facilitate their intracellular processing, especially in the case of patients with impaired metabolism of CblC-protein. The stability of the C-F bond in fluorinated Cbls displays remarkable stability upon F-Cbl(II) reduction to the Co(I) form is a remarkable finding, in stark contrast to the elimination of the Br atom in meso-brominated cobalamin is eliminated during this process.
{"title":"Meso-fluorinated cobalamins: insights into synthesis and redox properties.","authors":"Ilia A Dereven'kov, Vladimir S Osokin, Ilya A Khodov","doi":"10.1007/s00775-026-02133-4","DOIUrl":"https://doi.org/10.1007/s00775-026-02133-4","url":null,"abstract":"<p><p>Here, we present the first method of synthesis of cyano- (F-CNCbl) and aqua (F-H<sub>2</sub>OCbl) cobalamins, fluorinated at the C10 (meso) position of the corrin ring, and characterization of their redox properties. The reductive decyanation of F-CNCbl by glutathione and the reduction of F-H<sub>2</sub>OCbl to Co(II)-form (F-Cbl(II)) by glutathione or reduced nicotinamide adenine dinucleotide proceed more efficiently than the reactions involving unmodified complexes, which may facilitate their intracellular processing, especially in the case of patients with impaired metabolism of CblC-protein. The stability of the C-F bond in fluorinated Cbls displays remarkable stability upon F-Cbl(II) reduction to the Co(I) form is a remarkable finding, in stark contrast to the elimination of the Br atom in meso-brominated cobalamin is eliminated during this process.</p>","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146103585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-24DOI: 10.1007/s00775-025-02131-y
James P McEvoy
Advances in bioelectronic and renewable energy technologies make it important for undergraduate students to learn about bioelectrochemistry, and courses in the chemical and biological sciences provide opportunities for them to do so. This review surveys the ways in which bioelectrochemistry appears in these degree programs and evaluates effective educational practices in each case. Three key pedagogical challenges are identified: bioelectrochemical concepts are often abstract, the terminology is confusing and variable, and relevant material is fragmented across the curriculum. The review makes five recommendations to address these challenges. Educators are advised to (1) signpost connections across the curriculum to promote topic integration, (2) provide explicit guidance on terminology to pre-empt confusion, (3) use vivid biological examples to capture student attention and interest, (4) use active learning techniques to strengthen conceptual links, and (5) adopt published laboratory exercises that allow students to put bioelectrochemical theory into practice. In each case, examples are given to support implementation and enhance undergraduate student appreciation of the field.
{"title":"Making connections: teaching and learning bioelectrochemistry.","authors":"James P McEvoy","doi":"10.1007/s00775-025-02131-y","DOIUrl":"https://doi.org/10.1007/s00775-025-02131-y","url":null,"abstract":"<p><p>Advances in bioelectronic and renewable energy technologies make it important for undergraduate students to learn about bioelectrochemistry, and courses in the chemical and biological sciences provide opportunities for them to do so. This review surveys the ways in which bioelectrochemistry appears in these degree programs and evaluates effective educational practices in each case. Three key pedagogical challenges are identified: bioelectrochemical concepts are often abstract, the terminology is confusing and variable, and relevant material is fragmented across the curriculum. The review makes five recommendations to address these challenges. Educators are advised to (1) signpost connections across the curriculum to promote topic integration, (2) provide explicit guidance on terminology to pre-empt confusion, (3) use vivid biological examples to capture student attention and interest, (4) use active learning techniques to strengthen conceptual links, and (5) adopt published laboratory exercises that allow students to put bioelectrochemical theory into practice. In each case, examples are given to support implementation and enhance undergraduate student appreciation of the field.</p>","PeriodicalId":603,"journal":{"name":"Journal of Biological Inorganic Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145814664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}