Pub Date : 2021-03-31DOI: 10.4236/OJVM.2020.113007
B. U. Sayılkan, Y. Meral, Emre Küllük, D. Dalğın
The patient was admitted to OndokuzMayıs University Animal Hospital Internal Medicine outpatient clinic with complaints of epileptic seizures and hypothyroidism. A description of the patient’s owner is available in the history information. There was no physician information. Bradycardia was found in the electrocardiography of the patient. 2-D, M-Mode, PW, CW and Color doppler examinations were performed. Left-ventricular hypokinetic and mitral and tricuspidal valve movements were observed with limited M-Mode imaging. Anterior mitral orifice of 2 mm width was detected on septal mitral valve by PW doppler and color doppler. With this orifice, the presence of regurgitant jet, which covers LA at a rate of 1/3 and was 3.2 m/sec, together with mitral regurgitation (0.5 m/sec.), was demonstrated. PISA calculations; VFR (mL/s), ERO (mm2) and RVol (mL/pulse) values were calculated as if there were mitral regurgitation and data were obtained for mild-moderate mitral regurgitation. Therefore, no operative treatment of the orifice was recommended. Mitral valve orifice is a rare pathology and this is the first report in canine veterinary practice with degenerative mitral valve disorder. We aimed to underline the possibility of mitral orifice development in degenerative mitral valve disorders, known to present with vegetations and varying degrees of prolapsus, conventionally.
{"title":"Anterior Mitral Valve Orifice in a Dog","authors":"B. U. Sayılkan, Y. Meral, Emre Küllük, D. Dalğın","doi":"10.4236/OJVM.2020.113007","DOIUrl":"https://doi.org/10.4236/OJVM.2020.113007","url":null,"abstract":"The patient was admitted to OndokuzMayıs University Animal Hospital Internal Medicine outpatient clinic with complaints of epileptic seizures and hypothyroidism. A description of the patient’s owner is available in the history information. There was no physician information. Bradycardia was found in the electrocardiography of the patient. 2-D, M-Mode, PW, CW and Color doppler examinations were performed. Left-ventricular hypokinetic and mitral and tricuspidal valve movements were observed with limited M-Mode imaging. Anterior mitral orifice of 2 mm width was detected on septal mitral valve by PW doppler and color doppler. With this orifice, the presence of regurgitant jet, which covers LA at a rate of 1/3 and was 3.2 m/sec, together with mitral regurgitation (0.5 m/sec.), was demonstrated. PISA calculations; VFR (mL/s), ERO (mm2) and RVol (mL/pulse) values were calculated as if there were mitral regurgitation and data were obtained for mild-moderate mitral regurgitation. Therefore, no operative treatment of the orifice was recommended. Mitral valve orifice is a rare pathology and this is the first report in canine veterinary practice with degenerative mitral valve disorder. We aimed to underline the possibility of mitral orifice development in degenerative mitral valve disorders, known to present with vegetations and varying degrees of prolapsus, conventionally.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"11 1","pages":"117-123"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45488801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-22DOI: 10.4236/OJVM.2020.113006
Xavier De Jaeger, L. Meppiel, S. Endersby, A. Sparkes
Background: A number of specific synthetic pheromones have been commercially available for many years and used to help modify different problem behaviours exhibited by companion animals. Recently, a new synthetic feline pheromone complex has been patented and made available commercially. Objectives: This study was designed as an initial open-label uncontrolled trial to evaluate the potential impact of the new synthetic pheromone complex on a range of different problem behaviours in pet cats. Methods: 150 owned pet cats from either one-cat (n = 66) or two-cat (n = 84) households that had one or more of four defined problem behaviours (urine spraying, n = 31; scratching furnishings, n = 113; fear, n = 63; or inter-cat conflict, n = 25), were recruited to a 28-day study of a new plug-in diffuser containing the novel feline pheromone complex. Results: By day 28, significant (P values ≤ 0.01) improvements were seen in both the frequency and intensity of all four problem behaviours, as assessed by the owners using blinded questionnaires. A reduction in the frequency of individual problem behaviours was reported by 69.8% - 77.4% of owners and a reduction in the intensity of the problem by 64.0% - 74.2%. Conclusions: The results of this study support the concept that the new feline pheromone complex may have the ability to address multiple problem behaviours. Nevertheless, further controlled studies will be necessary and important to both confirm, and to fully assess the clinical efficacy of the product.
{"title":"An Initial Open-Label Study of a Novel Pheromone Complex for Use in Cats","authors":"Xavier De Jaeger, L. Meppiel, S. Endersby, A. Sparkes","doi":"10.4236/OJVM.2020.113006","DOIUrl":"https://doi.org/10.4236/OJVM.2020.113006","url":null,"abstract":"Background: A number of specific synthetic pheromones have been commercially \u0000available for many years and used to help modify different problem behaviours \u0000exhibited by companion animals. Recently, a new synthetic feline pheromone \u0000complex has been patented and made available commercially. Objectives: \u0000This study was designed as an initial open-label uncontrolled trial to evaluate \u0000the potential impact of the new synthetic pheromone complex on a range of \u0000different problem behaviours in pet cats. Methods: 150 owned pet cats \u0000from either one-cat (n = 66) or two-cat (n = 84) households that had one or \u0000more of four defined problem behaviours (urine spraying, n = 31; scratching \u0000furnishings, n = 113; fear, n = 63; or inter-cat conflict, n = 25), were \u0000recruited to a 28-day study of a new plug-in diffuser containing the novel \u0000feline pheromone complex. Results: By day 28, significant (P values ≤ \u00000.01) improvements were seen in both the frequency and intensity of all four \u0000problem behaviours, as assessed by the owners using blinded questionnaires. A \u0000reduction in the frequency of individual problem behaviours was reported by \u000069.8% - 77.4% of owners and a reduction in the intensity of the problem by 64.0% - 74.2%. Conclusions: \u0000The results of this study support the concept that the new feline pheromone \u0000complex may have the ability to address multiple problem behaviours. \u0000Nevertheless, further controlled studies will be necessary and important to \u0000both confirm, and to fully assess the clinical efficacy of the product.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"11 1","pages":"105-116"},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43961695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-04DOI: 10.4236/OJVM.2021.112005
Sofja Kosiara, A. Harrison
The ability to calm horses affects both the safety and well-being of human-horse relationships. However, not many natural calmatives are known, nor the efficacy of these in supporting a state of calmness in horses. This study used both qualitative and quantitative methods to test whether aromatherapy has a measurable and calming effect on equine facial expression and a range of physiological parameters. Nine horses of different ages, genders and breeds were included in a crossover design with humidified essential oils to determine the calming effect of vetiver (Vetiveria zizanioides), spikenard (Nardostachys jatamansi) and roman chamomile (Anthemis nobilis) in relation to water (negative control) and lavender oil (positive control) in horses standing still. The results revealed significantly lowered heart rate (P < 0.05 - <0.001) and respiratory tidal volume (P < 0.05 - <0.001) for the tested essential oils, while spikenard oil was best at inducing a relaxed facial expression (60% of the full-time scale for 8 horses; 75% of the full-time scale for 7 horses) and roman chamomile oil was statistically most successful at reducing the incidence of spontaneous muscle contractures in M. Temporalis (P < 0.001) and M. Cleidomastoideus (P < 0.05) compared to the other aromatherapy treatments. It is concluded that aromatherapy has both qualitative and quantitative effects on physiological parameters in static horses, and moreover, that essential oils appear to have a calming effect.
{"title":"The Effect of Aromatherapy on Equine Facial Expression, Heart Rate, Respiratory Tidal Volume and Spontaneous Muscle Contractures in M. Temporalis and M. Cleidomastoideus","authors":"Sofja Kosiara, A. Harrison","doi":"10.4236/OJVM.2021.112005","DOIUrl":"https://doi.org/10.4236/OJVM.2021.112005","url":null,"abstract":"The ability to calm horses affects both the safety \u0000and well-being of human-horse relationships. However, not many natural \u0000calmatives are known, nor the efficacy of these in supporting a state of \u0000calmness in horses. This study used both qualitative and quantitative methods \u0000to test whether aromatherapy has a measurable and calming effect on equine \u0000facial expression and a range of physiological parameters. Nine horses of \u0000different ages, genders and breeds were included in a crossover design with \u0000humidified essential oils to determine the calming effect of vetiver (Vetiveria \u0000zizanioides), spikenard (Nardostachys jatamansi) and roman chamomile \u0000(Anthemis nobilis) in relation to water (negative control) and lavender \u0000oil (positive control) in horses standing still. The results revealed \u0000significantly lowered heart rate (P < 0.05 - <0.001) and respiratory \u0000tidal volume (P < 0.05 - <0.001) for the tested essential oils, while \u0000spikenard oil was best at inducing a relaxed facial expression (60% of the \u0000full-time scale for 8 horses; 75% of the full-time scale for 7 horses) and \u0000roman chamomile oil was statistically most successful at reducing the incidence \u0000of spontaneous muscle contractures in M. Temporalis (P < 0.001) and M. \u0000Cleidomastoideus (P < 0.05) compared to the other aromatherapy treatments. \u0000It is concluded that aromatherapy has both qualitative and quantitative effects \u0000on physiological parameters in static horses, and moreover, that essential oils \u0000appear to have a calming effect.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49078375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-25DOI: 10.4236/OJVM.2021.111001
Prudence Mpundu, A. Mbewe, J. Muma, Gift Mwinga Sitali, C. Mubita, Musso Munyeme
Objectives: This study aimed to conduct a comparative assessment of bacterial cross-contamination in commercial and non-commercial processing plants including associated risk factors for bacterial contamination. Study Design: This was analytic cross sectional survey on bacterial contamination of broiler carcasses between different processing systems. Introduction: Zambia, like most African and Asian Countries, still practices “live-open non-commercial broiler carcass processing systems” besides the “closed abattoir based systems”. However, shelf life, spoilage and hygiene levels have been postulated to vary based on the type of processing system. Live-open non-commercial processing systems are popular among majority consumers owing to their perceived “freshness”, compared to commercially dressed chickens. In between, consumers have to balance freshness and quality assurance. Ultimately, this becomes inert, remotely but an important public health issue. However, lack of empirical evidence on safety levels to guide consumer product selection leaves them to speculation. It is this need to close this gap that created an impetus for us to undertake this study. Methods: Biological samples were collected before carcass wash and after carcass wash alongside a structured questionnaire that gathered risk-associated data. Standard microbiological enumeration methods were used to isolate bacteria and enumerate contamination. Results: Broiler carcasses processed from “open” non-commercial systems were more contaminated (45.6%) than “closed-abattoir” commercially processed systems (35%). Escherichia coli were major contaminants (71.3%) and few Salmonella spices (typhi or para-typhi) in 1.3%. Risk analysis indicates washing (method) of carcasses at commercial systems was significantly more risky for contamination than non-commercial ones. Major sources of contamination were “distance from water sources”. Increased volume of slaughters per day (>15,000 birds) for commercial systems accounted for increased cross-contamination, particularly, distance from water source was a ma-jor risk factor for contamination.
{"title":"Comparison of Bacterial Cross-Contamination among Broiler Carcasses between Commercial and Non-Commercial Processed System and Its Public Health Implications","authors":"Prudence Mpundu, A. Mbewe, J. Muma, Gift Mwinga Sitali, C. Mubita, Musso Munyeme","doi":"10.4236/OJVM.2021.111001","DOIUrl":"https://doi.org/10.4236/OJVM.2021.111001","url":null,"abstract":"Objectives: This study aimed to conduct a comparative assessment of bacterial cross-contamination in commercial and non-commercial processing plants including associated risk factors for bacterial contamination. Study Design: This was analytic cross sectional survey on bacterial contamination of broiler carcasses between different processing systems. Introduction: Zambia, like most African and Asian Countries, still practices “live-open non-commercial broiler carcass processing systems” besides the “closed abattoir based systems”. However, shelf life, spoilage and hygiene levels have been postulated to vary based on the type of processing system. Live-open non-commercial processing systems are popular among majority consumers owing to their perceived “freshness”, compared to commercially dressed chickens. In between, consumers have to balance freshness and quality assurance. Ultimately, this becomes inert, remotely but an important public health issue. However, lack of empirical evidence on safety levels to guide consumer product selection leaves them to speculation. It is this need to close this gap that created an impetus for us to undertake this study. Methods: Biological samples were collected before carcass wash and after carcass wash alongside a structured questionnaire that gathered risk-associated data. Standard microbiological enumeration methods were used to isolate bacteria and enumerate contamination. Results: Broiler carcasses processed from “open” non-commercial systems were more contaminated (45.6%) than “closed-abattoir” commercially processed systems (35%). Escherichia coli were major contaminants (71.3%) and few Salmonella spices (typhi or para-typhi) in 1.3%. Risk analysis indicates washing (method) of carcasses at commercial systems was significantly more risky for contamination than non-commercial ones. Major sources of contamination were “distance from water sources”. Increased volume of slaughters per day (>15,000 birds) for commercial systems accounted for increased cross-contamination, particularly, distance from water source was a ma-jor risk factor for contamination.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"11 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46665153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-25DOI: 10.4236/OJVM.2021.111002
V. Elbrønd, Rikke M. Schultz
Seven superficial myofascial kinetic lines have been described earlier in horses in a comparative dissection study to the human lines. The lines act as an anatomical basis for understanding locomotion, stabilization, and posture. Further dissections verified three profound equine lines comparable to those described in humans and a fourth line not described previously. Forty-four horses of different breed and gender were dissected, imaged and video recorded. The horses were euthanized due to reasons not related to this study. A Deep Ventral Line (DVL) very similar to that in the human was verified in these studies. The line spans from the insertion of the profound flexor tendon in the hindlimb to the base of the cranium and oral part of the cavities of the head. It includes the profound, hypaxial myofascial structures, the ventral coccygeal muscles, the psoas muscles, the diaphragm, the longus colli/capitis muscles and the ventral capital muscles. The inner lining of the pelvic, abdominal and thoracic cavities with all the organs, vessels and nerves are also included. The line is closely connected to the autonomic nervous system by the vagus nerve, the pelvic nerves, the sympathetic trunk and several of the prevertebral nerves and ganglia. The new line identified in this study, is a Deep Dorsal Line (DDL), which starts in the dorsal tail muscles. It comprises myofascial structures of the spinocostotransversal system from the tail to the head including the nuchal ligament. It connects to the dura mater and has a major role in controlling the motion and stabilization of the Columna vertebralis. Both the DDL and the DVL include the coccygeal myofascia and periosteum of the skull. Due to differences in biped and quadruped anatomy the Front Limb Adduction Line (FADL) and the Front Limb Abduction Line (FABL) differ from the human lines. The lines are identified as slings in the brachial and antebrachial regions. The FABL includes structures for abduction and internal rotation connecting to the Front Limb Retraction Line (FLRL), and the FADL structures of adduction and external rotation in close proximity to the Front Limb Protraction Line (FLPL). The front limb lines support the movement of the front limb around the “thoraco-scapula pivot joint” medially at the level of the upper third of the scapula. The DVL identified in this study is similar to the human DFL whereas the front limb lines differ somewhat from the deep human arm lines due to differences in bi- and quadruped anatomy and biomechanics. We have identified and described this new equine DDL. The lines altogether explain a profound body balance and confirm the three-dimensional equine fascial network, which is of great clinical and biomechanical importance.
{"title":"Deep Myofascial Kinetic Lines in Horses, Comparative Dissection Studies Derived from Humans","authors":"V. Elbrønd, Rikke M. Schultz","doi":"10.4236/OJVM.2021.111002","DOIUrl":"https://doi.org/10.4236/OJVM.2021.111002","url":null,"abstract":"Seven superficial myofascial kinetic lines have been described earlier in horses in a comparative dissection study to the human lines. The lines act as an anatomical basis for understanding locomotion, stabilization, and posture. Further dissections verified three profound equine lines comparable to those described in humans and a fourth line not described previously. Forty-four horses of different breed and gender were dissected, imaged and video recorded. The horses were euthanized due to reasons not related to this study. A Deep Ventral Line (DVL) very similar to that in the human was verified in these studies. The line spans from the insertion of the profound flexor tendon in the hindlimb to the base of the cranium and oral part of the cavities of the head. It includes the profound, hypaxial myofascial structures, the ventral coccygeal muscles, the psoas muscles, the diaphragm, the longus colli/capitis muscles and the ventral capital muscles. The inner lining of the pelvic, abdominal and thoracic cavities with all the organs, vessels and nerves are also included. The line is closely connected to the autonomic nervous system by the vagus nerve, the pelvic nerves, the sympathetic trunk and several of the prevertebral nerves and ganglia. The new line identified in this study, is a Deep Dorsal Line (DDL), which starts in the dorsal tail muscles. It comprises myofascial structures of the spinocostotransversal system from the tail to the head including the nuchal ligament. It connects to the dura mater and has a major role in controlling the motion and stabilization of the Columna vertebralis. Both the DDL and the DVL include the coccygeal myofascia and periosteum of the skull. Due to differences in biped and quadruped anatomy the Front Limb Adduction Line (FADL) and the Front Limb Abduction Line (FABL) differ from the human lines. The lines are identified as slings in the brachial and antebrachial regions. The FABL includes structures for abduction and internal rotation connecting to the Front Limb Retraction Line (FLRL), and the FADL structures of adduction and external rotation in close proximity to the Front Limb Protraction Line (FLPL). The front limb lines support the movement of the front limb around the “thoraco-scapula pivot joint” medially at the level of the upper third of the scapula. The DVL identified in this study is similar to the human DFL whereas the front limb lines differ somewhat from the deep human arm lines due to differences in bi- and quadruped anatomy and biomechanics. We have identified and described this new equine DDL. The lines altogether explain a profound body balance and confirm the three-dimensional equine fascial network, which is of great clinical and biomechanical importance.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"11 1","pages":"14-40"},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49499761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-25DOI: 10.4236/OJVM.2021.111003
Ngoumtsop Victor Herman, Tchoffo Hervé, Guiekep Nounamo Arthénice Jemima, M. Valence, N. Ferdinand
The present study was undertaken to evaluate the protective effects of Hydroethanolic leaves extract of Persea americana (HEPA) against Antouka Super®(AS) induced hepatotoxicity in male Japanese quail. In total, 40 immature male Japanese quails aged 28 days were used and divided equally into 5 groups. The groups were designed as the control group (received only a 10 ml/kg of distilled water) and the AS group (75 mg/kg b.w). Other three groups received AS (75 mg of AS/kg b.w) plus HEPA (50, 100, and 200 mg/kg b.w/day respectively) by the oral route. After 60 days of the experiment, the crushed liver was performed to obtain homogenate. The protective effects of HEPA on the biochemical parameters, oxidative stress biomarkers and histology changes in the liver were evaluated. The results indicated that AS treatment caused significant alterations in the clinical signs and behavior. It induces the increase in the content of Urea, Creatinine, Protein, AST and ALT in liver tissues and serum. The activities of enzymatic oxidative stress markers such as Superoxide Dismutase (SOD); Catalase (CAT) and Total Peroxidase (POD) also showed significant perturbations in AS-treated quails. Histopathological examination of the liver of AS-treated quails revealed liver lesions characterized by moderate to severe degenerative changes showing a number of hepatocytes undergo fatty changes, focal aggregation of the lymphocytes, multiple necrotic changes and inflammatory infiltrate. The administration of HEPA however, markedly ameliorated the toxicity of AS by protecting the levels of aforesaid biomarkers to near normal levels. These results suggested that HEPA due to its phytochemical constituents with antioxidant properties possesses significant effects against AS-induced toxicity. However, these effects were more pronounced at a dose of 200 mg/kg bw.
{"title":"Hepato-Preventive Effects of Hydroethanolic Leaves Extract of Persea americana Mill. (Lauraceae) “Avocado” against Antouka Super®Induced Damage in Male Japanese Quail (Coturnix coturnix Japonica)","authors":"Ngoumtsop Victor Herman, Tchoffo Hervé, Guiekep Nounamo Arthénice Jemima, M. Valence, N. Ferdinand","doi":"10.4236/OJVM.2021.111003","DOIUrl":"https://doi.org/10.4236/OJVM.2021.111003","url":null,"abstract":"The present study was undertaken to evaluate the protective effects of Hydroethanolic leaves extract of Persea americana (HEPA) against Antouka Super®(AS) induced hepatotoxicity in male Japanese quail. In total, 40 immature male Japanese quails aged 28 days were used and divided equally into 5 groups. The groups were designed as the control group (received only a 10 ml/kg of distilled water) and the AS group (75 mg/kg b.w). Other three groups received AS (75 mg of AS/kg b.w) plus HEPA (50, 100, and 200 mg/kg b.w/day respectively) by the oral route. After 60 days of the experiment, the crushed liver was performed to obtain homogenate. The protective effects of HEPA on the biochemical parameters, oxidative stress biomarkers and histology changes in the liver were evaluated. The results indicated that AS treatment caused significant alterations in the clinical signs and behavior. It induces the increase in the content of Urea, Creatinine, Protein, AST and ALT in liver tissues and serum. The activities of enzymatic oxidative stress markers such as Superoxide Dismutase (SOD); Catalase (CAT) and Total Peroxidase (POD) also showed significant perturbations in AS-treated quails. Histopathological examination of the liver of AS-treated quails revealed liver lesions characterized by moderate to severe degenerative changes showing a number of hepatocytes undergo fatty changes, focal aggregation of the lymphocytes, multiple necrotic changes and inflammatory infiltrate. The administration of HEPA however, markedly ameliorated the toxicity of AS by protecting the levels of aforesaid biomarkers to near normal levels. These results suggested that HEPA due to its phytochemical constituents with antioxidant properties possesses significant effects against AS-induced toxicity. However, these effects were more pronounced at a dose of 200 mg/kg bw.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47014688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-25DOI: 10.4236/OJVM.2021.111004
V. Ullrich, H. Apell
Electromagnetic fields (EMFs) can interact with biological tissues exerting positive as well as negative effects on cell viability, but the underlying sensing and signaling mechanisms are largely unknown. So far in excitable cells EMF exposure was postulated to cause Ca2+ influx through voltage-dependent Ca channels (VDCC) leading to cell activation and an antioxidant response. Upon further activation oxidative stress causing DNA damage or cell death may follow. Here we report collected evidence from literature that voltage dependent anion channels (VDAC) located not only in the outer microsomal membrane but also in the cytoplasmic membrane convert to Ca2+ conducting channels of varying capacities upon subtle changes of the applied EMF even in non-excitable cells like erythrocytes. Thus, VDAC can be targeted by external EMF in both types of membranes to release Ca2+ into the cytosol. The role of frequency, pulse modulation or polarization remains to be investigated in suitable cellular models. VDACs are associated with several other proteins, among which the 18 kDa translocator (TSPO) is of specific interest since it was characterized as the central benzodiazepine receptor in neurons. Exhibiting structural similarities with magnetoreceptors we propose that TSPO could sense the magnetic component of the EMF and thus together with VDAC could trigger physiological as well as pathological cellular responses. Pulsed EMFs in the frequency range of the brain-wave communication network may explain psychic disturbances of electromagnetic hypersensitive persons. An important support is provided from human psychology that states deficits like insomnia, anxiety or depression can be treated with diazepines that indicates apparent connections between the TSPO/VDAC complex and organismic responses to EMF.
{"title":"Electromagnetic Fields and Calcium Signaling by the Voltage Dependent Anion Channel","authors":"V. Ullrich, H. Apell","doi":"10.4236/OJVM.2021.111004","DOIUrl":"https://doi.org/10.4236/OJVM.2021.111004","url":null,"abstract":"Electromagnetic fields (EMFs) can interact with biological tissues exerting positive as well as negative effects on cell viability, but the underlying sensing and signaling mechanisms are largely unknown. So far in excitable cells EMF exposure was postulated to cause Ca2+ influx through voltage-dependent Ca channels (VDCC) leading to cell activation and an antioxidant response. Upon further activation oxidative stress causing DNA damage or cell death may follow. Here we report collected evidence from literature that voltage dependent anion channels (VDAC) located not only in the outer microsomal membrane but also in the cytoplasmic membrane convert to Ca2+ conducting channels of varying capacities upon subtle changes of the applied EMF even in non-excitable cells like erythrocytes. Thus, VDAC can be targeted by external EMF in both types of membranes to release Ca2+ into the cytosol. The role of frequency, pulse modulation or polarization remains to be investigated in suitable cellular models. VDACs are associated with several other proteins, among which the 18 kDa translocator (TSPO) is of specific interest since it was characterized as the central benzodiazepine receptor in neurons. Exhibiting structural similarities with magnetoreceptors we propose that TSPO could sense the magnetic component of the EMF and thus together with VDAC could trigger physiological as well as pathological cellular responses. Pulsed EMFs in the frequency range of the brain-wave communication network may explain psychic disturbances of electromagnetic hypersensitive persons. An important support is provided from human psychology that states deficits like insomnia, anxiety or depression can be treated with diazepines that indicates apparent connections between the TSPO/VDAC complex and organismic responses to EMF.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"11 1","pages":"57-86"},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43251769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.4236/ojvm.2021.1111022
Ahmed A. Omar, S. Harun-ur-Rashid, Md. Haydar Ali, B. Mohamed
{"title":"Prevalence of Bovine Tuberculosis in Sheep at Sadar and Parbatipur Upazila under Dinajpur District in Bangladesh","authors":"Ahmed A. Omar, S. Harun-ur-Rashid, Md. Haydar Ali, B. Mohamed","doi":"10.4236/ojvm.2021.1111022","DOIUrl":"https://doi.org/10.4236/ojvm.2021.1111022","url":null,"abstract":"","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70689276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.4236/ojvm.2021.1112023
Maged Gomaa Hemida, A. M. Ali, A. Alnaeem
{"title":"A Paucity of Detection of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Nucleic Acids in the Vaginal Secretions and the Urine of Some Naturally Infected Dromedary Camels","authors":"Maged Gomaa Hemida, A. M. Ali, A. Alnaeem","doi":"10.4236/ojvm.2021.1112023","DOIUrl":"https://doi.org/10.4236/ojvm.2021.1112023","url":null,"abstract":"","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70689621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.4236/ojvm.2021.119020
A. A. Oni, M. Oyeyemi, J. Atawalna
Forty testicles were used to carry out histomorphometry study on the testes, epididymides and spermatozoa of four indigenous breeds of bull found in Ibadan (Red Bororo (RB), Sokoto Gudali (SG), White Fulani (WF) and Dhali (DL)). The testicles were harvested immediately after the slaughter at the Bodija abattoir and transported to the laboratory in an insulated flask contain-ing warm water at 37˚C within 30 minutes. In the laboratory, the samples were dissected and histological sections of the right testis, right and left caudal epididymides taken from two bulls in each group. The tissues were fixed in Bouin’s fluid. They were processed in an automatic tissue processor, embedded in paraffin wax using the embedding system (Leica EG 1160) and sectioned with microtome at 4 microns. The sections were then stained by Haematoxylin and Eosin method and mounted and examined under a microscope. There was no significant difference between breed and seminiferous tubular diameter (STD) and testicular germinal height (TGEH). The mean STD ranged from 223.00 0.85 µm). The results of this study provide baseline data on the histomorphometry of the testes and epididymides and spermatozoa of some indigenous bulls.
{"title":"Histomorphometry of the Testes, Epididymides, and Spermatozoa of Four Indigenous Breeds of Bulls in Ibadan, Nigeria","authors":"A. A. Oni, M. Oyeyemi, J. Atawalna","doi":"10.4236/ojvm.2021.119020","DOIUrl":"https://doi.org/10.4236/ojvm.2021.119020","url":null,"abstract":"Forty testicles were used to carry out histomorphometry study on the testes, epididymides and spermatozoa of four indigenous breeds of bull found in Ibadan (Red Bororo (RB), Sokoto Gudali (SG), White Fulani (WF) and Dhali (DL)). The testicles were harvested immediately after the slaughter at the Bodija abattoir and transported to the laboratory in an insulated flask contain-ing warm water at 37˚C within 30 minutes. In the laboratory, the samples were dissected and histological sections of the right testis, right and left caudal epididymides taken from two bulls in each group. The tissues were fixed in Bouin’s fluid. They were processed in an automatic tissue processor, embedded in paraffin wax using the embedding system (Leica EG 1160) and sectioned with microtome at 4 microns. The sections were then stained by Haematoxylin and Eosin method and mounted and examined under a microscope. There was no significant difference between breed and seminiferous tubular diameter (STD) and testicular germinal height (TGEH). The mean STD ranged from 223.00 0.85 µm). The results of this study provide baseline data on the histomorphometry of the testes and epididymides and spermatozoa of some indigenous bulls.","PeriodicalId":61886,"journal":{"name":"兽医学(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70689786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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