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1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society最新文献

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Human hand stiffness during discrete point-to-point multi-joint movement 离散点对点多关节运动时人手刚度
H. Gomi, Y. Koike, M. Kawato
We compared dynamic hand stiffness during discrete multi-joint arm movement and static stiffness during posture control in order to investigate computational strategy for arm control by the central nervous system. Estimated stiffness during movement obtained by applying small perturbations were lower than those during static posture near the end of the movement. This result supports our simulation study that the virtual equilibrium trajectory of the hand is complicated in its shape to compensate nonlinear interaction forces of the multi-joint arm especially for fast movements.
为了研究中枢神经系统控制手臂的计算策略,我们比较了离散多关节手臂运动时的动态手部刚度和姿势控制时的静态手部刚度。通过施加小扰动获得的运动期间的估计刚度低于接近运动结束时的静态姿态。这一结果支持了我们的仿真研究,即手的虚拟平衡轨迹在其形状上是复杂的,以补偿多关节臂的非线性相互作用力,特别是在快速运动时。
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引用次数: 61
Prospects for finding unexpectedly low thresholds for the biological effects of exogenous ELF fields 寻找外源性极低频场生物效应的低阈值的前景
W. Pickard
Seemingly trivial exogenous ELF fields can have readily detectable biological effects if there is sufficient concentration of the fields upon appropriate structures, if each structure so affected modulates an associated sensitive process, and if the outputs of an ensemble of such processes are subsequently integrated; this mechanism is illustrated by the well-known sensitivity of sharks and rays to applied electric fields. Moreover, if an exogenous influence affects a physiological variable at all and if the probability distribution of that variable is related to the incidence of an observable sequela, then the incidence of that sequela can be doubled by an arbitrarily small change of the influence if the observable sequela was sufficiently rare to begin with! Finally, it is asserted that neither a specialized sensory system in an aquatic organism nor a speculative mechanism by which the incidence of rare events might be increased is sufficient to demonstrate convincingly the existence of ELF bioeffects of relevance to humans: only positive experimental data, quantitatively replicable upon demand, suffice to do that; and the generation of such data should be the primary goal of ELF bioeffects research.
如果电场足够集中在适当的结构上,如果受影响的每个结构都调节一个相关的敏感过程,如果这些过程的集合的输出随后被整合,那么看似微不足道的外源性极低频场可以很容易地检测到生物效应;众所周知,鲨鱼和鳐对外加电场的敏感性说明了这一机制。此外,如果外源性影响影响到一个生理变量,如果该变量的概率分布与可观察到的后遗症的发生率有关,那么,如果可观察到的后遗症一开始就足够罕见,那么该后遗症的发生率可以通过影响的任意小变化而翻倍!最后,有人断言,无论是水生生物的专门感觉系统,还是可能增加罕见事件发生率的推测机制,都不足以令人信服地证明与人类相关的极低频生物效应的存在:只有积极的实验数据,在需要时可在数量上复制,足以做到这一点;而产生这样的数据应该是ELF生物效应研究的首要目标。
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引用次数: 1
Comparison of computerized exercise ECG parameters in detecting myocardial ischemia 计算机化运动心电图参数检测心肌缺血的比较
R. Lehtinen, H. Sievanen, J. Malmivuo
The exercise ECG test is the most widely used method of evaluating myocardial ischemia, but its diagnostic accuracy is only about 70 %. Many studies introducing different diagnostic computerized exercise ECG parameters have been published, but according to the authors' knowledge there is no overall comparison of these parameters. We calculated 52 exercise ECG parameters from the ST-segment value, ST-segment shape and ST-segment/heart rate slope and compared the diagnostic power of these parameters by ROC-analysis. We found that ST-segment/heart rate slope has better diagnostic power than ST-segment depression or ST-segment shape alone. Another result was that the ST-segment shape seemed to be better diagnostic parameter than ST-segment depression when measuring an individual lead. However, further research with larger patient material is needed to get statistically significant differences between the parameters.
运动心电图试验是评价心肌缺血最常用的方法,但其诊断准确率仅为70%左右。已经发表了许多研究,介绍了不同的计算机化运动心电图诊断参数,但据笔者所知,没有对这些参数进行全面比较。我们从st段值、st段形状和st段/心率斜率计算52个运动心电图参数,并通过roc分析比较这些参数的诊断能力。我们发现st段/心率斜率比st段凹陷或st段形状单独具有更好的诊断能力。另一个结果是,当测量单个导联时,st段形状似乎比st段凹陷更好的诊断参数。然而,需要进一步研究更大的患者材料,以获得参数之间的统计学显著差异。
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引用次数: 1
Spectral analysis of the surface electrocardiogram in patients with Chagas disease 恰加斯病患者体表心电图的频谱分析
D. Jugo, Medina Ruben, Carrasco Hugo
Âbstraet-Vàz present paper deals with the analysis of the High Resolution Surface Electrocardiogram in patients with Chagas disease. The spectral estimation technique is based on the Discrete Fourier Transfom (DFT). evaluated over a 300 milliseconds segment situated around the QRS wave in the averaged signal, corresponding to three orthogonal derivations X, Y and Z. The results are presented as a spectro-temporal mapping of the signal and a comparison between normal subjects and patients with Chagas' disease based on the area between 0 and 300 Hz for a 76 milliseconds frame including the end of the QRS.
Âbstraet-Vàz本文分析了查加斯病患者的高分辨率表面心电图。频谱估计技术是基于离散傅里叶变换(DFT)的。在平均信号中位于QRS波周围的300毫秒片段上进行评估,对应于三个正交衍生X, Y和z。结果显示为信号的光谱时间映射以及正常受试者和恰加斯病患者之间的比较,该比较基于76毫秒帧(包括QRS结束)的0和300 Hz之间的区域。
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引用次数: 6
An explicit model for noninvasive measurement of blood samples 非侵入性血液样本测量的显式模型
D. Feng
An explicit model for tracer plasma time-activity curve (PTAC) is proposed based on practical experimental data in this paper, which can be potentially used to measure PTAC noninvasively from external probe or left ventricle images and to study the reliability of other physiological parameters measurements with positron emission tomography, which require PTAC as the input information.
基于实际实验数据,提出了示踪等离子体时间-活动曲线(PTAC)的显式模型,该模型可用于外探头或左心室图像无创测量PTAC,并研究以PTAC为输入信息的正电子发射断层扫描测量其他生理参数的可靠性。
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引用次数: 0
Properties of the upper arm vascular bed investigated by electrical impedance measurements in healthy subjects 用电阻抗测量方法研究健康人上臂血管床的特性
K. Visser, M. Gels, J. Muntinga, W. Terpstra, J. Schut
The fluid shifts of an upper arm tissue segment under an occluding cuff were estimated from electrical impedance measurements. This was done using parameter estimation with a model. The model included parameters describing the arterial and venous pressure-volume relationship. To gain insight into the precision of the method, repeated measurements were made on healthy volunteers. Most parameters showed a large variation (13–44 %). This variation could only partly be explained by variations in the measured quantities.
通过电阻抗测量,估计了封闭袖带下上臂组织段的流体位移。这是通过模型参数估计完成的。该模型包括描述动脉和静脉压力-容量关系的参数。为了深入了解该方法的准确性,对健康志愿者进行了重复测量。多数参数差异较大(13 - 44%)。这种变化只能部分地用测量量的变化来解释。
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引用次数: 0
A new system for 3D computerized X-ray angiography: First in vivo results 三维计算机x线血管造影新系统:首次体内实验结果
D. Saint-Félix, C. Picard, C. Ponchut, R. Romeas, A. Rougée, Y. Trousset, R. Carnpagnolo, P. Le Masson, P. Schermesser, S. Crocci, Y. Gandon, Y. Rolland, J. Scarabin, M. Amiel, G. Finet, T. Moll
A new system has been designed and built to validate the concept of 3D computerized Χ-ray angiography. It addresses all the difficulties met from the acquisition of raw data on a patient to the display of the reconstructed volume. The first in vivo results obtained with this system are presented.
一个新的系统已经设计和建立,以验证三维计算机Χ-ray血管造影的概念。它解决了从获取患者原始数据到显示重建体积所遇到的所有困难。本文介绍了用该系统获得的第一个体内结果。
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引用次数: 11
Causal probabilistic modelling for clinical decision support in the high dependency environment 高依赖环境下临床决策支持的因果概率模型
R. Summers, E. Carson, S. Andreassen
A physiologically-based model of the relevant cardiovascular, respiratory and associated processes of a patient resident in a high dependency environment is described. The model will be implemented using a Causal Probabilistic Network, and will be tuned to represent the individual patient. It will provide advice, for instance regarding changes in ventilator therapy, and the model will also be used to detect and correct equipment malfunction and operator error.
一个基于生理学的相关心血管、呼吸和相关过程的模型的病人居住在一个高度依赖的环境被描述。该模型将使用因果概率网络来实现,并将被调整为代表个体患者。它将提供建议,例如关于呼吸机治疗的变化,该模型还将用于检测和纠正设备故障和操作人员错误。
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引用次数: 1
Computer assisted planning of surgical procedures 计算机辅助外科手术计划
R. Kikinis, H. Cline, D. Altobelli, M. Halle, W. Lorensen, B. Rhodes, F. Jólesz
A system for computer-assisted planning of surgical procedures has been developped. Its components are a workstation with hardware accelerated 3D rendering board, a software environment and a set of procedures. Data sets from over 41 patients have been analyzed so far. We found a potential for improving the surgeons understanding of the anatomical situation he was going to face and for reducing the time spent during surgery to understand the altered anatomy.
一种计算机辅助外科手术计划系统已经开发出来。它的组成是一个带有硬件加速3D渲染板的工作站,一个软件环境和一套程序。到目前为止,已经分析了超过41名患者的数据集。我们发现有可能提高外科医生对他将要面对的解剖情况的理解,并减少手术中花在理解改变的解剖结构上的时间。
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引用次数: 0
Iterative Reprojection Reconstruction algorithm with attenuation correction applied to truncated projections in SPECT 基于衰减校正的SPECT截断投影迭代重投影重建算法
C. Riddell, M. Bourguignon, B. Bendriem, V. Frouin, A. Syrota
When SPECT sinograms are truncated, the Iterative Reprojection Reconstruction (IRR) algorithm based on the Radon transform cannot restore the distribution that would be obtained with the complete projection data set, even in the field of view taken as a region of interest. Nevertheless, when the attenuation characteristics are known and an attenuation correction is incorporated in the IRR scheme, the source distribution can be recovered in the field of view and, in the particular case of a contrasted attenuation map, even outside the region.
当SPECT图被截断时,基于Radon变换的迭代重投影重建(IRR)算法无法恢复完整投影数据集的分布,即使在视场作为感兴趣区域时也是如此。然而,当衰减特性已知并在IRR方案中加入衰减校正时,可以在视场中恢复源分布,在对比衰减图的特殊情况下,甚至可以在区域外恢复源分布。
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引用次数: 1
期刊
1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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