首页 > 最新文献

2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)最新文献

英文 中文
Nanostructured calcium phosphate coatings for medical implants 医用植入物用纳米结构磷酸钙涂层
Berkin B. Alexander, Deryabina V. Vera, Veselov V. Sergei
The change of the calcium phosphate film surface morphology depending on the mode of deposition and subsequent thermal annealing are investigated. It is shown that depending on the crystallization degree of the film surface roughness ranges from Ra = 0.007 um, RV = 0.05 um to Ra = 0.095 um, RV = 0.3 um. Depending on crystallization degree the potential from +1.5 to -1 V is formed on film surface.
研究了磷酸钙薄膜表面形貌随沉积方式和热处理方式的变化。结果表明,根据结晶程度的不同,膜的表面粗糙度从Ra = 0.007 um, RV = 0.05 um到Ra = 0.095 um, RV = 0.3 um不等。根据结晶程度的不同,薄膜表面形成+1.5 ~ -1 V的电位。
{"title":"Nanostructured calcium phosphate coatings for medical implants","authors":"Berkin B. Alexander, Deryabina V. Vera, Veselov V. Sergei","doi":"10.1109/SIBIRCON.2015.7361851","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361851","url":null,"abstract":"The change of the calcium phosphate film surface morphology depending on the mode of deposition and subsequent thermal annealing are investigated. It is shown that depending on the crystallization degree of the film surface roughness ranges from Ra = 0.007 um, RV = 0.05 um to Ra = 0.095 um, RV = 0.3 um. Depending on crystallization degree the potential from +1.5 to -1 V is formed on film surface.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"1 1","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90864331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical solution of inverse problem for secretion and kinetics of C-peptide model c肽分泌逆问题的数值解及动力学模型
S. Kabanikhin, D. Voronov, O. Krivorotko, A. Y. Belonog, A. Ilyin
The minimal model of insulin secretion based on C-peptide data (Toffolo et al., 1995) is presented in this report. The secretion model is identified on C-peptide taken in plasma; it must be integrated into a model of whole-body C-peptide kinetics. The kinetic model is the one proposed by (Eaton et al., 1980) and consists of 2 compartments. Compartment 1, accessible to measurement, represents plasma and rapidly equilibrating tissues, whereas compartment 2 represents tissues in slow exchange with plasma. This model allows estimating distribution of insulin in the blood and tissues. A new iterative algorithm for finding kinetic constants and secretion parameters is proposed. Numerical solution of inverse problem was obtained by using synthetic data. Different levels of noise were added to such data. The question of initial approximation is covered in this talk).
本报告提出了基于c肽数据的胰岛素分泌最小模型(Toffolo et al., 1995)。通过血浆c肽测定,确定了c肽的分泌模式;它必须整合到一个全身c肽动力学模型中。动力学模型由(Eaton et al., 1980)提出,由2个隔室组成。可测量的室1代表等离子体和快速平衡组织,而室2代表与等离子体缓慢交换的组织。这个模型可以估计胰岛素在血液和组织中的分布。提出了一种新的求解动力学常数和分泌参数的迭代算法。利用合成数据得到了反问题的数值解。这些数据中加入了不同程度的噪声。初值近似的问题将在本次演讲中讨论。
{"title":"Numerical solution of inverse problem for secretion and kinetics of C-peptide model","authors":"S. Kabanikhin, D. Voronov, O. Krivorotko, A. Y. Belonog, A. Ilyin","doi":"10.1109/SIBIRCON.2015.7361862","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361862","url":null,"abstract":"The minimal model of insulin secretion based on C-peptide data (Toffolo et al., 1995) is presented in this report. The secretion model is identified on C-peptide taken in plasma; it must be integrated into a model of whole-body C-peptide kinetics. The kinetic model is the one proposed by (Eaton et al., 1980) and consists of 2 compartments. Compartment 1, accessible to measurement, represents plasma and rapidly equilibrating tissues, whereas compartment 2 represents tissues in slow exchange with plasma. This model allows estimating distribution of insulin in the blood and tissues. A new iterative algorithm for finding kinetic constants and secretion parameters is proposed. Numerical solution of inverse problem was obtained by using synthetic data. Different levels of noise were added to such data. The question of initial approximation is covered in this talk).","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"21 1","pages":"108-112"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86100742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovative technologies in the study of articulatory-acoustic bases of indigenous ethnoses of Siberia (MRI, digital roentgenography and laryngography investigation) 西伯利亚土著民族发音-声学基础研究的创新技术(MRI、数字x线摄影和喉部摄影调查)
I. Selyutina, T. Ryzhikova, N. Urtegeshev, A. Dobrinina, A. Letyagin, A. Shevela
The study of the sound systems of the minority languages of the peoples of Siberia and the adjacent regions is based on the supposition that the articulatory-acoustic database being an attribute of ethnicity is a potential historical and linguistic source in the reconstruction of ethno-genetic processes. Instrumental methods have been used by the Novosibirsk phoneticians in the study of sound systems since the late 1960s. Since 2009, researchers from the three institutes of the Siberian branch of the Russian Academy of Sciences both of a philological and medical profile have been conducting a comprehensive interdisciplinary study of articulatory-acoustic bases of indigenous Siberian populations, using Magnetic-Resonance Imaging, digital Roentgenography and Laryngography1, An electronic database including somatic material on 46 idioms (languages, dialects and sub-dialects) has been created. The results of the study made adjustments to the traditional view of scientists about the Genesis of the autochthonous minority ethnic groups and their languages.
对西伯利亚和邻近地区少数民族语言的声音系统的研究是基于这样一种假设,即作为种族属性的发音-声学数据库是重建种族遗传过程的潜在历史和语言来源。自20世纪60年代末以来,新西伯利亚语音学家一直使用仪器方法研究声音系统。自2009年以来,来自俄罗斯科学院西伯利亚分院的三个研究所的语言学和医学研究人员一直在利用磁共振成像、数字x线摄影和喉部摄影技术,对西伯利亚土著人口的发音声学基础进行全面的跨学科研究,建立了一个电子数据库,其中包括46个习语(语言、方言和次方言)的身体材料。研究结果对科学家们关于少数民族的起源及其语言的传统观点进行了调整。
{"title":"Innovative technologies in the study of articulatory-acoustic bases of indigenous ethnoses of Siberia (MRI, digital roentgenography and laryngography investigation)","authors":"I. Selyutina, T. Ryzhikova, N. Urtegeshev, A. Dobrinina, A. Letyagin, A. Shevela","doi":"10.1109/SIBIRCON.2015.7361875","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361875","url":null,"abstract":"The study of the sound systems of the minority languages of the peoples of Siberia and the adjacent regions is based on the supposition that the articulatory-acoustic database being an attribute of ethnicity is a potential historical and linguistic source in the reconstruction of ethno-genetic processes. Instrumental methods have been used by the Novosibirsk phoneticians in the study of sound systems since the late 1960s. Since 2009, researchers from the three institutes of the Siberian branch of the Russian Academy of Sciences both of a philological and medical profile have been conducting a comprehensive interdisciplinary study of articulatory-acoustic bases of indigenous Siberian populations, using Magnetic-Resonance Imaging, digital Roentgenography and Laryngography1, An electronic database including somatic material on 46 idioms (languages, dialects and sub-dialects) has been created. The results of the study made adjustments to the traditional view of scientists about the Genesis of the autochthonous minority ethnic groups and their languages.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"8 1","pages":"165-170"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81792136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic use of the resistive device in COPD patients 阻性装置在慢性阻塞性肺病患者中的诊断应用
O. V. Grishin, V. Gultyaeva, D. Uryumtsev, M. Zinchenko, V. Grishin
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is diagnosed in later or very advanced stages. The aim of the study was to evaluate feasibility of low respiratory resistive load (LRRL) in patients with COPD for a new objective method of early COPD diagnostics and to examine changes in pulmonary gas exchange during LRRL. METHODS: The study involved eleven patients with mild or moderate COPD and fourteen healthy adult volunteers. After anthropometric and spirometric measuring, pulmonary gas exchange was measured for 7 minutes using the breath-by-breath method under two conditions: 1) without respiratory resistive load (WRL); 2) with LRRL 0.4 cm H2O · l-1 · s. Valve system (Intersurgical, UK) was used as a resistive device. RESULTS: Decrease in oxygen consumption (VO2) and carbon dioxide production (VCO2) during LRRL was significantly greater in COPD patients than in healthy subjects (14 vs. 8 %, p<;0.009 and 16 vs. 10 %, p<;0.020 respectively). In contrast, tidal volume increased by 13 % in healthy subjects only. CONCLUSION: Pulmonary gas exchange shift during low respiratory resistive load appears to be a feasible criterion of early COPD diagnostics. Future research is needed to examine sensitivity and specificity of the method.
慢性阻塞性肺疾病(COPD)在晚期或非常晚期被诊断出来。本研究的目的是评估低呼吸阻力负荷(LRRL)在COPD患者中作为一种新的、客观的COPD早期诊断方法的可行性,并研究LRRL期间肺气体交换的变化。方法:该研究纳入了11名轻中度COPD患者和14名健康成人志愿者。在人体测量和肺活量测量后,在两种情况下,采用呼吸法测量肺气体交换7分钟:1)无呼吸阻力负荷(WRL);2) LRRL为0.4 cm H2O·l-1·s。采用英国Intersurgical公司的瓣膜系统作为电阻装置。结果:COPD患者在LRRL期间的耗氧量(VO2)和二氧化碳产生(VCO2)的下降明显大于健康受试者(分别为14%比8%,p< 0.009和16%比10%,p< 0.020)。相比之下,只有健康受试者的潮气量增加了13%。结论:低呼吸阻力负荷时肺气体交换移位是COPD早期诊断的可行标准。需要进一步的研究来检验该方法的敏感性和特异性。
{"title":"Diagnostic use of the resistive device in COPD patients","authors":"O. V. Grishin, V. Gultyaeva, D. Uryumtsev, M. Zinchenko, V. Grishin","doi":"10.1109/SIBIRCON.2015.7361871","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361871","url":null,"abstract":"INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is diagnosed in later or very advanced stages. The aim of the study was to evaluate feasibility of low respiratory resistive load (LRRL) in patients with COPD for a new objective method of early COPD diagnostics and to examine changes in pulmonary gas exchange during LRRL. METHODS: The study involved eleven patients with mild or moderate COPD and fourteen healthy adult volunteers. After anthropometric and spirometric measuring, pulmonary gas exchange was measured for 7 minutes using the breath-by-breath method under two conditions: 1) without respiratory resistive load (WRL); 2) with LRRL 0.4 cm H2O · l-1 · s. Valve system (Intersurgical, UK) was used as a resistive device. RESULTS: Decrease in oxygen consumption (VO2) and carbon dioxide production (VCO2) during LRRL was significantly greater in COPD patients than in healthy subjects (14 vs. 8 %, p<;0.009 and 16 vs. 10 %, p<;0.020 respectively). In contrast, tidal volume increased by 13 % in healthy subjects only. CONCLUSION: Pulmonary gas exchange shift during low respiratory resistive load appears to be a feasible criterion of early COPD diagnostics. Future research is needed to examine sensitivity and specificity of the method.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"1 4 1","pages":"146-149"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78537166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automatic text classification and property extraction applications in medicine 自动文本分类和属性提取在医学中的应用
A. Kolonin
The paper describes different cases of combination of statistical, rule-based and pattern-based approaches for text classification, entity extraction and discernment of entity properties applied to medical domain.
本文介绍了基于统计、基于规则和基于模式的文本分类、实体提取和实体属性识别方法在医学领域的不同应用实例。
{"title":"Automatic text classification and property extraction applications in medicine","authors":"A. Kolonin","doi":"10.1109/SIBIRCON.2015.7361868","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361868","url":null,"abstract":"The paper describes different cases of combination of statistical, rule-based and pattern-based approaches for text classification, entity extraction and discernment of entity properties applied to medical domain.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"96 1","pages":"133-137"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77269388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Active exoskeleton tracking control system design via singular perturbation technique 基于奇异摄动技术的主动外骨骼跟踪控制系统设计
V. Yurkevich
Problem of active exoskeleton control system design is discussed. The presented design methodology of the tracking PID multivariable controller for active exoskeleton control system is based on time-scale separation technique (singular perturbation technique). The required control accuracy, almost perfect rejection of nonlinearities, unknown external disturbances, and interactions between exoskeleton joints are provided due to increase of time-scale separation degree between the fast and slow modes that are artificially forced in the closed-loop control system. Simulation results for trajectory tracking control of a two-link exoskeleton manipulator are presented as an example of the proposed design methodology application.
讨论了主动外骨骼控制系统的设计问题。提出了一种基于时间尺度分离技术(奇异摄动技术)的外骨骼主动控制系统跟踪PID多变量控制器设计方法。由于在闭环控制系统中人为强制的快、慢模式之间的时间尺度分离程度的增加,提供了所需的控制精度、几乎完美的非线性抑制、未知的外部干扰和外骨骼关节之间的相互作用。以双连杆外骨骼机械臂轨迹跟踪控制为例,给出了该设计方法的应用实例。
{"title":"Active exoskeleton tracking control system design via singular perturbation technique","authors":"V. Yurkevich","doi":"10.1109/SIBIRCON.2015.7361866","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361866","url":null,"abstract":"Problem of active exoskeleton control system design is discussed. The presented design methodology of the tracking PID multivariable controller for active exoskeleton control system is based on time-scale separation technique (singular perturbation technique). The required control accuracy, almost perfect rejection of nonlinearities, unknown external disturbances, and interactions between exoskeleton joints are provided due to increase of time-scale separation degree between the fast and slow modes that are artificially forced in the closed-loop control system. Simulation results for trajectory tracking control of a two-link exoskeleton manipulator are presented as an example of the proposed design methodology application.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"54 1","pages":"124-129"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86786749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clustering of independent components of EEG in determining individual characteristics of reactions related to a moral choice 在确定与道德选择有关的反应的个体特征时,脑电图独立成分的聚类
A. Bocharov, Q. A. Bogomaz, A. Savostyanov, G. Knyazev, A. Budakova, M. Zaleshin, T. Astakhova
Moral judgment can be defined as the evaluation of actions with respect to norms and values established in a society. In the modern world, morality is considered as the social capital, which determines a level of society well-being. Participants were showed 24 moral dilemma and 24 control task vignettes represented artist-sketched cartoons of control and dilemma scenarios. For all participants and every experimental condition, the model of localization equivalent dipoles electroenæphalogram (EEG) components was made. Individual localization of EEG electrodes was matched with a model of localization of electrodes of head, which was used for determining the equivalent dipoles. Event-related spectral perturbations were calculated to estimate induced responses via the EEGLAB toolbox. The dataset was prepared for clustering by the original PCA method. The correction for multiple comparisons was made by the False Discovery Rate method. To determine the correlations cortical sources of EEG activity with Social Intellect, sLORETA was applied to the data. Differences between moral dilemmas and control tasks without moral choice were found in delta, theta, alpha and beta diapasons in clusters localized in temporal and frontal lobe. Social intellect positively correlated with difference between the test interval and the baseline during making moral dilemma choice in theta in the left middle temporal gyrus and beta in the left middle frontal gyrus.
道德判断可以定义为对社会中建立的规范和价值观的行为的评价。在现代社会,道德被认为是一种社会资本,它决定着一个社会的幸福水平。参与者被展示了24个道德困境和24个控制任务小插曲,这些小插曲代表了艺术家绘制的控制和困境场景的漫画。针对所有被试和每个实验条件,建立了等效偶极子EEG成分的局部化模型。将脑电电极的个体定位与头部电极定位模型相匹配,利用该模型确定等效偶极子。通过EEGLAB工具箱计算与事件相关的谱扰动来估计诱导响应。采用原始PCA方法对数据集进行聚类处理。采用错误发现率法对多重比较进行校正。为了确定脑电图活动的皮层源与社会智力的相关性,我们对数据进行了sLORETA分析。道德困境与无道德选择的控制任务在颞叶和额叶的δ、θ、α和β偶波中存在差异。社会智力与道德困境选择时测试间隔与基线的差异在左颞中回θ和左额中回β中呈正相关。
{"title":"Clustering of independent components of EEG in determining individual characteristics of reactions related to a moral choice","authors":"A. Bocharov, Q. A. Bogomaz, A. Savostyanov, G. Knyazev, A. Budakova, M. Zaleshin, T. Astakhova","doi":"10.1109/SIBIRCON.2015.7361861","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361861","url":null,"abstract":"Moral judgment can be defined as the evaluation of actions with respect to norms and values established in a society. In the modern world, morality is considered as the social capital, which determines a level of society well-being. Participants were showed 24 moral dilemma and 24 control task vignettes represented artist-sketched cartoons of control and dilemma scenarios. For all participants and every experimental condition, the model of localization equivalent dipoles electroenæphalogram (EEG) components was made. Individual localization of EEG electrodes was matched with a model of localization of electrodes of head, which was used for determining the equivalent dipoles. Event-related spectral perturbations were calculated to estimate induced responses via the EEGLAB toolbox. The dataset was prepared for clustering by the original PCA method. The correction for multiple comparisons was made by the False Discovery Rate method. To determine the correlations cortical sources of EEG activity with Social Intellect, sLORETA was applied to the data. Differences between moral dilemmas and control tasks without moral choice were found in delta, theta, alpha and beta diapasons in clusters localized in temporal and frontal lobe. Social intellect positively correlated with difference between the test interval and the baseline during making moral dilemma choice in theta in the left middle temporal gyrus and beta in the left middle frontal gyrus.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"109 1","pages":"104-107"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74966610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Software system for the diagnosis of the spine diseases using case-based reasoning 基于案例推理的脊柱疾病诊断软件系统
D. Palchunov, G. Yakhyaeva, O. Yasinskaya
The paper describes the Diagnostic Panel Software System designed for the “spinal deformity and degenerative diseases of the spine” subject domain. The work is based on the methods of statistical processing of the data obtained from medical documents written in a natural language. The software system based on patient's clinical and laboratory test results helps physicians determine a preliminary diagnosis of the patient and get quick information on the necessity of certain measures for final diagnosis and selection of the optimal treatment strategy. The Diagnostic Panel Software System uses case-based approach for the representation of knowledge extracted from a variety of natural language texts. Developed case-based approach is based on model-theoretic methods of subject domain ontology formalization. For the processing of knowledge represented in system the formal concept analysis methodology is used.
本文介绍了为“脊柱畸形和脊柱退行性疾病”主题领域设计的诊断面板软件系统。这项工作是基于从以自然语言书写的医疗文件中获得的数据的统计处理方法。该软件系统基于患者的临床和实验室检查结果,帮助医生确定患者的初步诊断,并快速获得某些措施的必要性信息,以最终诊断和选择最佳治疗策略。诊断面板软件系统使用基于案例的方法来表示从各种自然语言文本中提取的知识。基于案例的方法是在主题领域本体形式化的模型理论方法的基础上发展起来的。对于系统所表示的知识的处理,采用形式概念分析方法。
{"title":"Software system for the diagnosis of the spine diseases using case-based reasoning","authors":"D. Palchunov, G. Yakhyaeva, O. Yasinskaya","doi":"10.1109/SIBIRCON.2015.7361884","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361884","url":null,"abstract":"The paper describes the Diagnostic Panel Software System designed for the “spinal deformity and degenerative diseases of the spine” subject domain. The work is based on the methods of statistical processing of the data obtained from medical documents written in a natural language. The software system based on patient's clinical and laboratory test results helps physicians determine a preliminary diagnosis of the patient and get quick information on the necessity of certain measures for final diagnosis and selection of the optimal treatment strategy. The Diagnostic Panel Software System uses case-based approach for the representation of knowledge extracted from a variety of natural language texts. Developed case-based approach is based on model-theoretic methods of subject domain ontology formalization. For the processing of knowledge represented in system the formal concept analysis methodology is used.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"1 1","pages":"205-210"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91329343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Stochastic simulation of fluctuation-induced enzyme kinetics in vicinity of traps, based on probabilistic tunneling and diffusion mechanisms 基于概率隧道和扩散机制的陷阱附近波动诱导酶动力学的随机模拟
K. Sabelfeld
A stochastic algorithm for simulation of fluctuation-induced enzyme kinetics is developed. The method is generally well applicable when the reactions occur in low-dimensional and disordered media such as biological ones. We suggest a generalization of the Michaelis - Menten scheme of enzyme kinetics that is extended to simulate the quantum tunneling phenomena in the catalytic cycles of enzymatic processes. The stochastic method is suggested as a generalization of the technique developed in our recent studies [12], [13] where this method was developed to describe the annihilation of spatially separate electrons and holes in a disordered semiconductor. The stochastic technique is based on the spatially inhomogeneous, nonlinear integro-differential Smoluchowski equations with random source term. We focus in this study on the spatial distribution, and numerically investigate the segregation in the case of a source with a continuous generation in time and randomly distributed in space. The stochastic particle method presented is based on a probabilistic interpretation of the underlying process as a stochastic Markov process of interacting particle system in discrete but randomly progressed time instances. The segregation is analyzed through the correlation analysis of the vector random field of concentrations which appears to be isotropic in space and stationary in time.
提出了一种模拟波动诱导酶动力学的随机算法。该方法一般适用于低维、无序介质(如生物介质)的反应。我们建议推广酶动力学的Michaelis - Menten方案,扩展到模拟酶过程催化循环中的量子隧道现象。随机方法是我们在最近的研究[12],[13]中发展的技术的推广,该方法被用来描述无序半导体中空间分离的电子和空穴的湮灭。随机技术是基于具有随机源项的空间非齐次非线性积分微分Smoluchowski方程。本文从空间分布的角度出发,用数值方法研究了在时间上连续产生、空间上随机分布的源的分离问题。所提出的随机粒子方法是基于对相互作用的粒子系统在离散但随机进展的时间实例中的随机马尔可夫过程的概率解释。通过对浓度矢量随机场的相关分析,分析了其在空间上各向同性,在时间上平稳的偏析现象。
{"title":"Stochastic simulation of fluctuation-induced enzyme kinetics in vicinity of traps, based on probabilistic tunneling and diffusion mechanisms","authors":"K. Sabelfeld","doi":"10.1109/SIBIRCON.2015.7361879","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361879","url":null,"abstract":"A stochastic algorithm for simulation of fluctuation-induced enzyme kinetics is developed. The method is generally well applicable when the reactions occur in low-dimensional and disordered media such as biological ones. We suggest a generalization of the Michaelis - Menten scheme of enzyme kinetics that is extended to simulate the quantum tunneling phenomena in the catalytic cycles of enzymatic processes. The stochastic method is suggested as a generalization of the technique developed in our recent studies [12], [13] where this method was developed to describe the annihilation of spatially separate electrons and holes in a disordered semiconductor. The stochastic technique is based on the spatially inhomogeneous, nonlinear integro-differential Smoluchowski equations with random source term. We focus in this study on the spatial distribution, and numerically investigate the segregation in the case of a source with a continuous generation in time and randomly distributed in space. The stochastic particle method presented is based on a probabilistic interpretation of the underlying process as a stochastic Markov process of interacting particle system in discrete but randomly progressed time instances. The segregation is analyzed through the correlation analysis of the vector random field of concentrations which appears to be isotropic in space and stationary in time.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"124 1","pages":"186-190"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77458597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Searching and using of time intervals of brain activity in a problem of solving process by estimation of negentropy of EEG 脑电负熵估计求解过程中脑活动时间间隔的搜索与利用
Kirill Chagin, A. Savostyanov
In the analysis of a brain activity it is actual to find time intervals that represents only brain activity. We have developed a new software instrument that helps to search and visualize such intervals. The base assumption of this work is that distribution of the amplitude of signal that represents brain activity is significantly different from a Gaussian distribution. So we use negentropy as an indicator of intervals of brain dynamics. As a result, the developed instrument helps to analyze EEG information visually and make further mathematical calculations with the results.
在对大脑活动的分析中,找到只代表大脑活动的时间间隔是很实际的。我们开发了一种新的软件工具,可以帮助搜索和可视化这些间隔。这项工作的基本假设是,代表大脑活动的信号振幅的分布与高斯分布有很大不同。所以我们用负熵作为大脑动态间隔的指示器。因此,所开发的仪器有助于可视化地分析脑电信号,并根据结果进行进一步的数学计算。
{"title":"Searching and using of time intervals of brain activity in a problem of solving process by estimation of negentropy of EEG","authors":"Kirill Chagin, A. Savostyanov","doi":"10.1109/SIBIRCON.2015.7361886","DOIUrl":"https://doi.org/10.1109/SIBIRCON.2015.7361886","url":null,"abstract":"In the analysis of a brain activity it is actual to find time intervals that represents only brain activity. We have developed a new software instrument that helps to search and visualize such intervals. The base assumption of this work is that distribution of the amplitude of signal that represents brain activity is significantly different from a Gaussian distribution. So we use negentropy as an indicator of intervals of brain dynamics. As a result, the developed instrument helps to analyze EEG information visually and make further mathematical calculations with the results.","PeriodicalId":6503,"journal":{"name":"2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)","volume":"72 1","pages":"217-220"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74182404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1