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Optimization of multi-cluster fracturing in deep reservoirs based on stress field reconstruction effect 基于应力场重建效应的深部储层多簇压裂优化
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2026-01-17 DOI: 10.1007/s10409-025-25372-x
Jinbo Li  (, ), Siwei Meng  (, ), He Liu  (, ), Suling Wang  (, ), Kangxing Dong  (, ), Qiuyu Lu  (, )

Since rock plasticity under in-situ conditions poses challenges during fracturing stimulation, extensive research is necessary on deep gas and oil reserves, which will be the primary area of future development. This paper created a competitive, multi-cluster fracture propagation model that considered elastoplastic rock deformation and nonlinear fracture characteristics in deep reservoirs. It also proposed an optimal fracture design of “dense fracture distribution, non-uniform perforation and alternating staged fracturing” based on stress field reconstruction. The findings indicated that suitably reducing the spacing between clusters and increasing the number of perforated clusters minimized local in-situ stress variations through stress interference among fractures. This mitigated the limiting effect of plastic deformation on the propagation of hydraulic fractures, demonstrating a viable approach for enhancing the expansion of fractures in deep reservoirs. The elastoplastic fracture propagation mechanism was examined to elucidate the advantages of close-cutting fracturing technology. The impact of various fracture techniques was analyzed using stress field reconstruction. Alternate fracturing displayed a high degree of stress reconstruction with an extensive propagation range, which facilitated the propagation of multiple fracture clusters in the subsequent fracturing section. The findings offer a theoretical basis for fracture design of deep reservoirs.

由于原位条件下岩石的塑性给压裂改造带来了挑战,因此有必要对深部油气储量进行广泛的研究,这将是未来开发的重点领域。本文建立了一个考虑深部储层岩石弹塑性变形和非线性裂缝特征的竞争性多簇裂缝扩展模型。提出了基于应力场重建的“裂缝密集分布、射孔不均匀、分段交替压裂”的裂缝优化设计方案。研究结果表明,适当减小簇间距和增加射孔簇数量可以通过裂缝间应力干扰最小化局部地应力变化。这减轻了塑性变形对水力裂缝扩展的限制作用,证明了一种增强深层储层裂缝扩展的可行方法。研究了裂缝的弹塑性扩展机理,阐明了近切缝压裂技术的优越性。利用应力场重建技术,分析了各种压裂技术的影响。交替压裂的应力重建程度高,扩展范围广,有利于后续压裂段中多个裂缝簇的扩展。研究结果为深部储层裂缝设计提供了理论依据。
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引用次数: 0
Vibration suppression performance analysis of a novel vibration isolation-absorption system 一种新型隔振吸振系统的减振性能分析
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2026-01-17 DOI: 10.1007/s10409-025-25064-x
Shihua Zhou  (, ), Yiyan Wang  (, ), Zeyao Mu  (, ), Tingshuo Zhang  (, ), Xuan Li  (, ), Zhaohui Ren  (, )

Inspired by the walking, jumping, and running of quadrupeds, a novel vibration isolation-absorption (BVIA) platform is proposed by applying a bistratal X-shaped structure and a multi-vertebra structure. Based on the mechanical-constitutive relationship, the static and dynamic models of the BVIA platform are established, and the force/stiffness-displacement curves are applied to reveal the loading capacity and quasi-zero stiffness characteristics. The vibration suppression performances of different parameters are investigated by amplitude-frequency curve and displacement transmissibility, and the results are verified by numerical methods. From the results, it can be found that the resonance peak significantly decreases due to the mutual promotion of vibration isolation and vibration absorption. The vibration suppression performance of the BVIA structure can be tuned flexibly by initial installation angle, rod length ratio, layer number, absorbed mass, stiffness coefficient, horizontal spring length, and excitation amplitudes. The proposed BVIA structure provides a useful reference for reducing the resonance peak and improving the vibration suppression performance in practical engineering applications.

摘要以四足动物的行走、跳跃和奔跑为灵感,采用双侧x型结构和多椎体结构,设计了一种新型的隔振吸振平台。基于力学-本构关系,建立了BVIA平台的静态和动态模型,利用力/刚度-位移曲线揭示了BVIA平台的承载能力和准零刚度特性。通过幅频曲线和位移传递率分析了不同参数下的减振性能,并通过数值方法对结果进行了验证。从结果可以看出,由于隔振和吸振的相互促进,共振峰明显减小。BVIA结构的减振性能可以通过初始安装角度、杆长比、层数、吸收质量、刚度系数、水平弹簧长度和激励幅值等因素进行灵活调节。所提出的BVIA结构为实际工程应用中降低共振峰、提高减振性能提供了有益的参考。
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引用次数: 0
Prediction of pressure coefficient distributions for basic aerodynamic configurations via point cloud characterization 通过点云特性预测基本气动构型的压力系数分布
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2026-01-17 DOI: 10.1007/s10409-025-25138-x
Qiming Guan  (, ), Weiwei Zhang  (, )

Data-driven approaches have shown great advantage in rapidly and accurately predicting pressure coefficient distributions, which is of crucial importance to efficient aircraft design. Nevertheless, most data-driven approaches still encounter limitations in characterizing diverse aerodynamic configurations and adapting to varying grid densities, which have hindered their engineering applicability. In response to these challenges, this work adopts point clouds, a specific type of geometric data structure that is inherently suitable for uniformly characterizing diverse 2D/3D geometric shapes as the input for deep learning-based prediction of pressure coefficient distribution. By augmenting the dimensions of point cloud coordinates for local feature enhancement and utilizing the symmetric function “max pooling” to extract global features, the proposed aerodynamic model establishes the mapping between point cloud coordinates and pressure coefficients. Basic aerodynamic configurations like airfoils and wings are employed as test cases, the results demonstrate that the proposed model achieves both high accuracy and robust generalizability across variable geometries. For class-shape transformation-perturbed airfoils, the prediction error can be reduced to one-third of that of the conventional parameterization-based model. For airfoils selected in the University of Illinois Urbana-Champaign airfoil dataset, among which airfoil profiles are widely distributed, the average error of the proposed approach remains approximately 1.5%, whereas the parameterization-based model may fail. For wings, the prediction error still stays below 2.5%. Finally, the model exhibits strong robustness and generalizability across different point cloud densities. In conclusion, this work makes a breakthrough in predicting pressure coefficient distribution for variable geometric configurations, establishing the foundational framework for designing a large model capable of predicting distributed aerodynamic loads in aerospace applications.

数据驱动方法在快速准确地预测压力系数分布方面显示出巨大的优势,这对飞机的高效设计至关重要。然而,大多数数据驱动的方法在表征不同的气动结构和适应不同的网格密度方面仍然存在局限性,这阻碍了它们的工程适用性。为了应对这些挑战,本工作采用点云作为基于深度学习的压力系数分布预测的输入,点云是一种特定类型的几何数据结构,它本质上适合于统一表征各种2D/3D几何形状。该模型通过增加点云坐标的维数进行局部特征增强,利用“最大池化”对称函数提取全局特征,建立点云坐标与压力系数之间的映射关系。以翼型和机翼等基本气动结构为例进行了试验,结果表明该模型具有较高的精度和较强的泛化能力。对于类形变形扰动的翼型,预测误差可以降低到传统参数化模型的三分之一。对于伊利诺伊大学厄巴纳-香槟分校翼型数据集中选择的翼型,其中翼型分布广泛,该方法的平均误差保持在1.5%左右,而基于参数化的模型可能会失败。对于翅膀,预测误差仍然保持在2.5%以下。最后,该模型在不同点云密度下具有较强的鲁棒性和泛化性。总之,本工作在预测可变几何构型的压力系数分布方面取得了突破,为设计能够预测航空航天应用中分布气动载荷的大型模型奠定了基础框架。
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引用次数: 0
Microscopic mechanism analysis and crystal plasticity modeling of high-temperature creep behavior of selective laser melted IN718 选择性激光熔化IN718高温蠕变行为的微观机理分析及晶体塑性建模
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2026-01-17 DOI: 10.1007/s10409-025-25554-x
Kaiyang Zhu  (, ), Yajun Yu  (, ), Shuheng Wang  (, ), Zichen Deng  (, )

Due to their lightweight and monolithic forming characteristics, selective laser melted (SLM) nickel-based superalloys exhibit broad potential applications in aerospace and automotive industries. However, their unique microstructure leads to distinctive creep behavior. It is crucial to clarify the microstructural characteristics and underlying creep mechanisms of these alloys. In this work, creep experiments of SLM IN718 were conducted under different temperatures and holding stresses. And the evolution of grain size, precipitate state, and dislocation density in IN718 was investigated by scanning electron microscope and electron backscatter diffraction. Both carbide precipitation and dislocation density were identified as the main factors weakening the creep life and ductility of SLM IN718. Experimental results indicated that higher initial dislocation density and finer grain size lead to a reduction in creep life. Moreover, the precipitation of carbides and M23C6 under elevated temperature and high holding stress promotes micro-crack propagation and weakens creep strength. To simulate the mechanical behavior observed in high-temperature creep experiments, a crystal plasticity model coupling dislocations and precipitated solutes was developed based on the microstructural characteristics and deformation mechanisms of SLM IN718. This model enhances the fundamental understanding of the micro-mechanisms underlying the creep behavior of SLM IN718 and provides valuable insights for optimizing the design of high-performance components under extreme conditions.

选择性激光熔化镍基高温合金由于其轻量化和整体成形的特点,在航空航天和汽车工业中具有广泛的应用前景。然而,它们独特的微观结构导致了不同的蠕变行为。弄清这些合金的显微组织特征和潜在的蠕变机制至关重要。本文对SLM IN718在不同温度和保温应力下进行了蠕变试验。通过扫描电镜和电子背散射衍射研究了IN718晶粒尺寸、析出态和位错密度的演变。碳化物析出和位错密度是影响IN718合金蠕变寿命和塑性的主要因素。实验结果表明,较高的初始位错密度和较细的晶粒尺寸导致蠕变寿命降低。高温和高保温应力下碳化物和M23C6的析出促进了微裂纹扩展,降低了蠕变强度。为了模拟高温蠕变实验中观察到的力学行为,基于SLM IN718的显微组织特征和变形机理,建立了位错与析出溶质耦合的晶体塑性模型。该模型增强了对SLM IN718蠕变行为微观机制的基本理解,并为在极端条件下优化高性能部件的设计提供了有价值的见解。
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引用次数: 0
FDPI-DeepONet: A novel integration for 3D airfoil flow field computation FDPI-DeepONet:一种新的三维翼型流场计算集成
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2026-01-17 DOI: 10.1007/s10409-025-25215-x
Pengyu Wang  (, ), Bolin Pan  (, ), Zhe Liu  (, ), Liangjie Gao  (, )

This study focuses on the application of physically informed neural networks (PINNs) in three-dimensional (3D) airfoil flow field computation. Given that PINNs face challenges such as high dimensionality, network architecture design, data requirements, numerical stability, and physical constraints formulation when dealing with this problem, the fluid dynamics PINN with DeepONet (FDPI-DeepONet) network is proposed. It combines the advantages of PINN physical constraint modeling and DeepONet data-driven learning, utilizes branch networks with different functions of the two to collaborate with the backbone network, represents the 3D flow field through Cartesian coordinates, and is trained based on the DeepONet framework and the loss function of physical information. The experiments are tested with M6 and NACA0012 airfoil data, and the results show that FDPI-DeepONet performs excellently in terms of prediction accuracy and computational resource consumption, e.g., it outperforms the comparative methods in terms of average R2 metrics, and the computation time is reduced significantly. The network effectively overcomes challenges and provides efficient solutions to complex fluid dynamics problems.

本文研究了物理信息神经网络在三维翼型流场计算中的应用。针对PINN在处理该问题时面临的高维数、网络架构设计、数据需求、数值稳定性、物理约束表述等挑战,提出了基于DeepONet的流体动力学PINN (FDPI-DeepONet)网络。它结合了PINN物理约束建模和DeepONet数据驱动学习的优点,利用两者不同功能的分支网络与骨干网络协同,通过笛卡尔坐标表示三维流场,并基于DeepONet框架和物理信息损失函数进行训练。用M6和NACA0012翼型数据进行了实验测试,结果表明,FDPI-DeepONet在预测精度和计算资源消耗方面表现优异,平均R2指标优于对比方法,计算时间显著缩短。该网络有效地克服了各种挑战,为复杂的流体动力学问题提供了高效的解决方案。
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引用次数: 0
A high-performance parallel algorithm based on problem independent machine learning (PIML) for large-scale topology optimization 基于问题独立机器学习(PIML)的大规模拓扑优化高性能并行算法
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2026-01-14 DOI: 10.1007/s10409-025-25942-x
Xinyu Ma  (, ), Mengcheng Huang  (, ), Zongliang Du  (, ), Yilin Guo  (, ), Chang Liu  (, ), Yue Mei  (, ), Xu Guo  (, )

Although supplying extensive design space, the curse of dimensionality restricts the widespread application of large-scale topology optimization in practical engineering. Various acceleration techniques have been integrated with topology optimization, achieving significant attention and progress in large-scale problems. This work aims to investigate how much benefit can be obtained by combining parallel computing and machine learning techniques to enhance the efficiency of large-scale topology optimization algorithms. Accordingly, a parallel problem independent machine learning (PIML)-enhanced topology optimization method is proposed. The PIML model substantially reduces the dimension of the condensed stiffness matrix and its computational cost, and parallel computing reduces the workload per process and enables the application of a parallel multigrid solver. Besides, several techniques, such as matrix-free implementation, direct condensation of uniform coarse elements, and adjusting computational resource limits, have been developed to enhance computational efficiency. The weak scaling efficiency, strong scaling speedup, and maximum achievable efficiency of the proposed method are validated across multiple numerical examples, showing significant improvement in the tractable problem size and solution efficiency compared to traditional topology optimization algorithms.

虽然提供了广泛的设计空间,但维数诅咒限制了大规模拓扑优化在实际工程中的广泛应用。各种加速技术已经与拓扑优化相结合,在大规模问题上取得了重大的关注和进展。本研究旨在探讨将并行计算和机器学习技术相结合可以获得多大的好处,以提高大规模拓扑优化算法的效率。据此,提出了一种并行问题独立机器学习(PIML)增强拓扑优化方法。PIML模型大大降低了压缩刚度矩阵的维数和计算成本,并行计算减少了每个过程的工作量,使并行多网格求解器的应用成为可能。此外,还开发了无矩阵实现、均匀粗元素直接凝聚和调整计算资源限制等技术来提高计算效率。通过多个算例验证了该方法的弱缩放效率、强缩放加速和最大可达效率,与传统拓扑优化算法相比,在可处理问题规模和求解效率方面有显著提高。
{"title":"A high-performance parallel algorithm based on problem independent machine learning (PIML) for large-scale topology optimization","authors":"Xinyu Ma \u0000 (,&nbsp;),&nbsp;Mengcheng Huang \u0000 (,&nbsp;),&nbsp;Zongliang Du \u0000 (,&nbsp;),&nbsp;Yilin Guo \u0000 (,&nbsp;),&nbsp;Chang Liu \u0000 (,&nbsp;),&nbsp;Yue Mei \u0000 (,&nbsp;),&nbsp;Xu Guo \u0000 (,&nbsp;)","doi":"10.1007/s10409-025-25942-x","DOIUrl":"10.1007/s10409-025-25942-x","url":null,"abstract":"<div><p>Although supplying extensive design space, the curse of dimensionality restricts the widespread application of large-scale topology optimization in practical engineering. Various acceleration techniques have been integrated with topology optimization, achieving significant attention and progress in large-scale problems. This work aims to investigate how much benefit can be obtained by combining parallel computing and machine learning techniques to enhance the efficiency of large-scale topology optimization algorithms. Accordingly, a parallel problem independent machine learning (PIML)-enhanced topology optimization method is proposed. The PIML model substantially reduces the dimension of the condensed stiffness matrix and its computational cost, and parallel computing reduces the workload per process and enables the application of a parallel multigrid solver. Besides, several techniques, such as matrix-free implementation, direct condensation of uniform coarse elements, and adjusting computational resource limits, have been developed to enhance computational efficiency. The weak scaling efficiency, strong scaling speedup, and maximum achievable efficiency of the proposed method are validated across multiple numerical examples, showing significant improvement in the tractable problem size and solution efficiency compared to traditional topology optimization algorithms.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":7109,"journal":{"name":"Acta Mechanica Sinica","volume":"42 3","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145982753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstructing flow fields from sparse measurements using a convolutional autoencoder integrated with an Informer model 利用集成了Informer模型的卷积自编码器从稀疏测量中重建流场
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2025-11-18 DOI: 10.1007/s10409-025-25013-x
Yulu Liu  (, ), Jiakun Long  (, ), Bofu Wang  (, ), Tienchong Chang  (, ), Xiang Qiu  (, )

This paper explores the use of sparse time-series data from flow systems, acquired through sensors or other means, to predict flow fields using deep learning techniques. This area of research holds substantial scientific significance and practical application value. The time-series data measured from different points typically contain spatial correlation and temporal features, which, when utilized effectively, can contribute to reconstructing flow fields. In this study, a convolutional autoencoder is applied to reduce the dimensionality of the flow field. Subsequently, an Informer neural network and a convolutional neural network are employed to extract low-dimensional representations of the flow field from the measurement data. A specially designed loss function bridges these latent features to establish a mapping between measurement point sequences and flow fields. The hybrid model is validated using data from both numerical simulations and experimental measurements. Results demonstrate that this method effectively predicts velocity and pressure fields from sparse data, showcasing its potential for practical flow field reconstruction tasks.

本文探讨了通过传感器或其他手段获取的流系统稀疏时间序列数据的使用,利用深度学习技术预测流场。这一领域的研究具有重大的科学意义和实际应用价值。从不同地点测量的时间序列数据通常包含空间相关性和时间特征,如果有效利用这些特征,可以有助于流场的重建。本研究采用卷积自编码器对流场进行降维。随后,利用Informer神经网络和卷积神经网络从测量数据中提取流场的低维表示。一个特别设计的损失函数桥接这些潜在的特征,建立测点序列和流场之间的映射。利用数值模拟和实验测量数据对混合模型进行了验证。结果表明,该方法可以有效地从稀疏数据中预测速度场和压力场,显示了其在实际流场重建任务中的潜力。
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引用次数: 0
High-efficiency theoretical model for predicting contact forces and deformations in threaded connections under complex loading 复杂载荷下螺纹连接接触力和变形的高效预测理论模型
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2025-11-18 DOI: 10.1007/s10409-025-25027-x
Zhao Liu  (, ), Zeyu Qi  (, ), Xuefeng Wang  (, ), Caishan Liu  (, )

Threaded connection is a common structural form in mechanical engineering, with their complex nonlinear behavior under combined loading critically affecting structural performance. While existing simplified models and finite element analysis (FEA) methods describe force distribution under single loading conditions, accurately modeling threaded connections under complex loading remains challenging. This paper proposes a simplified theoretical model to efficiently predict contact forces and deformation distributions under tension, torsion, bending, and shear. The model treats bolt and nut bodies as Euler-Bernoulli beams and represents thread stiffness using equivalent trapezoidal cantilever beams, reducing computational complexity while retaining essential mechanical characteristics. The paper introduces reference helical curves and derives a deformation coordination relationship based on contact constraints. The model’s calculations are validated against FEA results, demonstrating both high precision and significant computational efficiency under complex loading conditions. This work provides an efficient and reliable tool for analyzing threaded connections, offering promising engineering applications.

螺纹连接是机械工程中常见的一种结构形式,其在组合荷载作用下的复杂非线性行为对结构的性能影响很大。虽然现有的简化模型和有限元分析(FEA)方法描述了单载荷条件下的力分布,但在复杂载荷下准确建模螺纹连接仍然具有挑战性。本文提出了一种简化的理论模型,可以有效地预测在拉伸、扭转、弯曲和剪切作用下的接触力和变形分布。该模型将螺栓和螺母体视为欧拉-伯努利梁,并使用等效梯形悬臂梁表示螺纹刚度,在保留基本力学特性的同时降低了计算复杂度。引入参考螺旋曲线,推导出基于接触约束的变形协调关系。通过有限元结果验证了该模型的计算结果,在复杂载荷条件下具有较高的计算精度和显著的计算效率。这项工作为分析螺纹连接提供了高效可靠的工具,具有很好的工程应用前景。
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引用次数: 0
Investigation on dynamic response of ship structure under multi-load combined action of underwater explosion considering cavitation effect 考虑空化效应的水下爆炸多载联合作用下舰船结构动力响应研究
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2025-10-31 DOI: 10.1007/s10409-024-24527-x
Yufan Chen  (, ), Jian Qin  (, ), Zhichao Lai  (, ), Xiangyao Meng  (, ), Yanbo Wen  (, ), Yipeng Jiang  (, ), Zhenhuang Guan  (, ), Ruiyuan Huang  (, )

In this paper, the load characteristics of shock wave, bubble pulsating water jet and cavitation closure are studied by carrying out underwater explosion experiments and numerical simulation of fixed square plates with 2.5, 5 and 10 g trinitrotoluene. The results show that under the combined action of multiple loads, the impulse of bubble pulsation and water jet load plays a leading role in the process of underwater explosion, and the impulse of cavitation closure load is greater than that of shock wave. The damage to the structure cannot be ignored, and the pressure time-history curve presents a “multi-peak” state, and it is pointed out that the water jet is a concentrated load. Then, the dynamic response of the full-scale model of the ship under the combined action of multiple loads is studied, and the dynamic response of the ship under different cabin water depths and different explosion distances is discussed. The results show that when the ship is empty, the damage degree of the ship is the most serious, and the influence of cavitation effect on the half cabin is weaker than that of the empty cabin, so the damage degree is the second, and the damage degree is the smallest when the cabin is full. When the distance parameter is less than 0.68, the shock wave and the after flow play a leading role in the dynamic response of the ship. When the distance parameter is between 0.68 and 1.38, the combined action of the bubble pulsating water jet and the cavitation closure multi-load causes the main damage to the ship. When the distance parameter is greater than 1.38, the bubble pulsation and the cavitation closure load play a leading role.

本文通过2.5、5和10 g三硝基甲苯的水下爆炸实验和数值模拟,研究了激波、气泡脉动水射流和空化闭合的载荷特性。结果表明:在多种载荷的共同作用下,气泡脉动和水射流载荷的冲击在水下爆炸过程中起主导作用,空化闭合载荷的冲击大于激波的冲击;对结构的破坏不容忽视,压力时程曲线呈现“多峰”状态,并指出水射流是集中荷载。然后,研究了多载荷联合作用下船舶全尺寸模型的动力响应,并讨论了不同舱室水深和不同爆炸距离下船舶的动力响应。结果表明:空舱时,船舶的损伤程度最严重,空舱时空化效应对半舱的影响弱于空舱,因此损伤程度次之,满舱时损伤程度最小。当距离参数小于0.68时,激波和后流对船舶动力响应起主导作用。当距离参数在0.68 ~ 1.38之间时,气泡脉动水射流与空化闭合多载的共同作用对船舶造成主要损伤。当距离参数大于1.38时,气泡脉动和空化闭合载荷起主导作用。
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引用次数: 0
A novel central pattern generator model for gait movements of rat hindlimbs 一种新的大鼠后肢步态运动中枢模式生成模型
IF 4.6 2区 工程技术 Q1 ENGINEERING, MECHANICAL Pub Date : 2025-10-31 DOI: 10.1007/s10409-025-24629-x
Bochao An  (, ), Fang Han  (, ), Ying Yu  (, ), Qingyun Wang  (, )

Central pattern generators (CPGs) are neural circuits which are found in both invertebrates and vertebrates, and are capable of generating rhythmic patterns of neural activity without receiving any rhythmic input. The mechanism by which CPG controls alternating and turning movements in vertebrates has not yet been fully understood. In this paper, a new CPG model for rat hindlimbs is proposed to unravel the above mechanism based on recent physiological experimental results. The model is obtained by adding commissural interneurons (CINs, including V0, V3, and CINi populations) and chx10 Gi neurons into Deng’s CPG model. Based on our proposed CPG model, different alternating gaits in the rat hindlimb model can be achieved by ablating different populations of commissural interneurons, which is consistent with physiological experimental findings. Then, turning movements are studied by applying unilateral excitatory and inhibitory stimuli to chx10 Gi neurons which are connected to the flexion side of the CPG with inhibitory synapses. It is found that unilateral activation leads to turning towards the same side, while unilateral inhibition results in turning towards the opposite side, which is also consistent with the results in physiological experiments. Finally, the ion-channel control mechanism of CPG burst rhythms is investigated, and it is found that the CPG burst rhythm is most sensitive to sodium ion channels, with a significantly greater impact than the influence of reciprocal inhibition on the rhythm. The proposed CPG model provides a new perspective for understanding motor neural mechanism of vertebrates, and also could be adopted in motion control of hindlimb robots.

中枢模式发生器(CPGs)是在无脊椎动物和脊椎动物中都存在的神经回路,能够在不接受任何节律输入的情况下产生神经活动的节律模式。CPG控制脊椎动物交替和旋转运动的机制尚未完全了解。本文基于近年来的生理实验结果,提出了一种新的大鼠后肢CPG模型来揭示上述机制。该模型是通过在Deng的CPG模型中加入互交中间神经元(CINs,包括V0、V3和CINi种群)和chx10 Gi神经元而得到的。基于CPG模型,通过切除不同数量的交节中间神经元,可以实现大鼠后肢模型的不同交替步态,这与生理实验结果一致。然后,通过对chx10 Gi神经元施加单侧兴奋性和抑制性刺激来研究旋转运动,chx10 Gi神经元通过抑制性突触连接CPG屈曲侧。发现单侧激活导致向同侧转动,单侧抑制导致向相反侧转动,这也与生理实验结果一致。最后,对CPG爆发节律的离子通道调控机制进行了研究,发现CPG爆发节律对钠离子通道最为敏感,其影响显著大于互抑对节律的影响。所提出的CPG模型为理解脊椎动物的运动神经机制提供了新的视角,也可用于后肢机器人的运动控制。
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