Pub Date : 2024-07-15DOI: 10.1186/s40580-024-00436-3
Jinsub Park, Yugyeong Je, Joonho Kim, Je Myoung Park, Joong-Eon Jung, Hyeonsik Cheong, Sang Wook Lee, Kwanpyo Kim
γ-GeSe is a newly identified polymorph among group-IV monochalcogenides, characterized by a distinctive interatomic bonding configuration. Despite its promising applications in electrical and thermal domains, the experimental verification of its mechanical and thermal properties remains unreported. Here, we experimentally characterize the in-plane Young’s modulus (E) and thermal conductivity ((:kappa:)) of γ-GeSe. The mechanical vibrational modes of freestanding γ-GeSe flakes are measured using optical interferometry. Nano-indentation via atomic force microscopy is also conducted to induce mechanical deformation and to extract the E. Comparison with finite-element simulations reveals that the E is 97.3(:pm:)7.5 GPa as determined by optical interferometry and 109.4(:pm:)13.5 GPa as established through the nano-indentation method. Additionally, optothermal Raman spectroscopy reveals that γ-GeSe has a lattice thermal conductivity of 2.3 (:pm:) 0.4 Wm−1K−1 and a total thermal conductivity of 7.5 (:pm:) 0.4 Wm−1K−1 in the in-plane direction at room temperature. The notably high (:E/kappa:) ratio in γ-GeSe, compared to other layered materials, underscores its distinctive structural and dynamic characteristics.
{"title":"Unveiling the distinctive mechanical and thermal properties of γ-GeSe","authors":"Jinsub Park, Yugyeong Je, Joonho Kim, Je Myoung Park, Joong-Eon Jung, Hyeonsik Cheong, Sang Wook Lee, Kwanpyo Kim","doi":"10.1186/s40580-024-00436-3","DOIUrl":"10.1186/s40580-024-00436-3","url":null,"abstract":"<div><p>γ-GeSe is a newly identified polymorph among group-IV monochalcogenides, characterized by a distinctive interatomic bonding configuration. Despite its promising applications in electrical and thermal domains, the experimental verification of its mechanical and thermal properties remains unreported. Here, we experimentally characterize the in-plane Young’s modulus (<i>E</i>) and thermal conductivity (<span>(:kappa:)</span>) of γ-GeSe. The mechanical vibrational modes of freestanding γ-GeSe flakes are measured using optical interferometry. Nano-indentation via atomic force microscopy is also conducted to induce mechanical deformation and to extract the <i>E</i>. Comparison with finite-element simulations reveals that the <i>E</i> is 97.3<span>(:pm:)</span>7.5 GPa as determined by optical interferometry and 109.4<span>(:pm:)</span>13.5 GPa as established through the nano-indentation method. Additionally, optothermal Raman spectroscopy reveals that γ-GeSe has a lattice thermal conductivity of 2.3 <span>(:pm:)</span> 0.4 Wm<sup>−1</sup>K<sup>−1</sup> and a total thermal conductivity of 7.5 <span>(:pm:)</span> 0.4 Wm<sup>−1</sup>K<sup>−1</sup> in the in-plane direction at room temperature. The notably high <span>(:E/kappa:)</span> ratio in γ-GeSe, compared to other layered materials, underscores its distinctive structural and dynamic characteristics.</p></div>","PeriodicalId":712,"journal":{"name":"Nano Convergence","volume":null,"pages":null},"PeriodicalIF":13.4,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://nanoconvergencejournal.springeropen.com/counter/pdf/10.1186/s40580-024-00436-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141618922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-11DOI: 10.1186/s40580-024-00434-5
Ming Yao Ho, Songhan Liu, Bengang Xing
Bacteria extracellular vesicles (BEVs), characterized as the lipid bilayer membrane-surrounded nanoparticles filled with molecular cargo from parent cells, play fundamental roles in the bacteria growth and pathogenesis, as well as facilitating essential interaction between bacteria and host systems. Notably, benefiting from their unique biological functions, BEVs hold great promise as novel nanopharmaceuticals for diverse biomedical potential, attracting significant interest from both industry and academia. Typically, BEVs are evaluated as promising drug delivery platforms, on account of their intrinsic cell-targeting capability, ease of versatile cargo engineering, and capability to penetrate physiological barriers. Moreover, attributing to considerable intrinsic immunogenicity, BEVs are able to interact with the host immune system to boost immunotherapy as the novel nanovaccine against a wide range of diseases. Towards these significant directions, in this review, we elucidate the nature of BEVs and their role in activating host immune response for a better understanding of BEV-based nanopharmaceuticals’ development. Additionally, we also systematically summarize recent advances in BEVs for achieving the target delivery of genetic material, therapeutic agents, and functional materials. Furthermore, vaccination strategies using BEVs are carefully covered, illustrating their flexible therapeutic potential in combating bacterial infections, viral infections, and cancer. Finally, the current hurdles and further outlook of these BEV-based nanopharmaceuticals will also be provided.