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The visual field following acute primary angle closure. 锐角闭合后的视野。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790318.X
Tin Aung, A. Looi, A. Looi, P. Chew
PURPOSETo determine the frequency and type of visual field loss six months after an episode of acute primary angle closure (APAC), and to identify risk factors for the development of such field loss.METHODSThis was a cross sectional observational study. All patients who suffered from an episode of APAC at two Singapore hospitals over a one-year period underwent static automated threshold perimetry six months after presentation.RESULTS38% of (29) patients with APAC have significant visual field defects six months after the acute episode. The majority of those with abnormal fields had hemifield defects, consistent with nerve fiber bundle pattern loss. Those with pre-existing chronic glaucoma or who develop a rise in intraocular pressure during follow-up are at risk of visual field loss. The risk of visual field loss is also significant if the duration of symptoms exceeds 7 days.CONCLUSIONSThe frequency of visual field loss at 6 months after APAC was low at only 38%. As the majority of eyes have no evidence of detectable functional damage developing as a consequence of the acute episode, APAC may not be blinding if treated promptly and adequately.
目的了解急性原发性闭角术(APAC)发作6个月后视野丧失的频率和类型,并确定发生这种视野丧失的危险因素。方法采用横断面观察性研究。所有在新加坡两家医院一年内发生APAC发作的患者在就诊后6个月接受了静态自动阈值周边测量。结果29例APAC患者中有38%在急性发作6个月后出现明显的视野缺损。大部分野区异常者为半野区缺损,与神经纤维束模式丧失一致。既往患有慢性青光眼或随访期间眼压升高的患者有视野丧失的风险。如果症状持续超过7天,视野丧失的风险也很大。结论APAC术后6个月视野丧失发生率较低,仅为38%。由于大多数眼睛在急性发作后没有可检测到的功能损伤的证据,如果治疗及时和充分,APAC可能不会致盲。
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引用次数: 45
Antenatal sonographic diagnosis of dacryocystocele. 泪囊膨出的产前超声诊断。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790328.X
V. D’addario, V. Pinto, A. Anfossi, A. Del Bianco, F. Cantatore
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引用次数: 8
Autologous blood injection for marked overfiltration early after trabeculectomy with mitomycin C. 自体血液注射治疗丝裂霉素C小梁切除术后早期明显过滤。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790320.X
K. Okada, H. Tsukamoto, M. Masumoto, K. Jian, M. Okada, H. Mochizuki, H. Mishima
PURPOSEAfter trabeculectomy with mitomycin C, extremely low intraocular pressure (IOP) with excess filtration may cause hypotonous maculopathy in the early postoperative period. We evaluated the effect of injecting autologous blood on reversing early postoperative marked hypotony after trabeculectomy with mitomycin C.METHODSTrabeculectomy with mitomycin C was performed in 258 eyes between 1994 and 1998. Peribleb autologous blood injection was performed in five eyes in which pressure patches were ineffective in reversing excess filtration. Approximately 0.1 to 0.3 ml of whole unclotted blood was slowly injected at least 3 mm from the edge of the flap using a sterile 27-gauge needle.RESULTSNone of these eyes developed hypotonous maculopathy after injection. After a mean 31-month follow-up, all eyes had well-controlled IOP and visual acuity in three eyes was much improved. Postoperative complications included mild IOP elevation in one eye treated with laser suturelysis, and fibrinous pupillary membrane in one eye.CONCLUSIONIn the early postoperative period, autologous blood injection is effective in reversing excess filtration.
目的丝裂霉素C小梁切除术后,极低的眼压(IOP)伴过度滤过可引起术后早期低张力黄斑病变。方法1994 ~ 1998年对258只眼行丝裂霉素C小梁切除术。5眼行外泡自体血液注射,压贴对过度滤过的逆转无效。用27号无菌针从皮瓣边缘至少3mm处缓慢注射约0.1至0.3 ml未凝固的全血。结果注射后无一例发生黄斑低张力病变。在平均31个月的随访后,所有眼睛的IOP控制良好,其中三只眼睛的视力明显改善。术后并发症包括单眼轻度IOP升高及单眼纤维性瞳孔膜。结论术后早期自体注血可有效逆转过度滤过。
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引用次数: 12
Additive IOP-reducing effect of latanoprost in patients insufficiently controlled on timolol. 拉坦前列素对替马洛尔控制不足患者的附加性降眼压作用。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790316.X
A. Bron, Philippe Denis, J. Nordmann, J. Rouland, E. Sellem, Marianne Johansson
PURPOSETo evaluate the effect on intraocular pressure (IOP) of switching from timolol to latanoprost or adding latanoprost to timolol in patients with open angle glaucoma or ocular hypertension where IOP is not adequately controlled with timolol.METHODSThis was a 6-week, double-masked, randomised multi-centre study. 53 patients with primary open angle glaucoma, capsular glaucoma, or ocular hypertension with an IOP of at least 21 mmHg on current therapy were recruited. After a run-in period of at least 2 weeks on timolol, 5 mg/ml twice daily, patients were randomised to one of three groups. One group continued on timolol, one switched from timolol to latanoprost, 50 microg/ml once daily, and a third group received latanoprost in addition to timolol. The efficacy was evaluated by comparing IOP at 9 AM at baseline and after 6 weeks of treatment.RESULTSIOP at baseline and after 6 weeks of treatment (mean +/- SEM) were 24.2 +/- 0.9 and 23.8 +/- 1.0 mmHg (n = 16) for patients continuing on timolol, 26.3 +/- 1.2 and 19.6 +/- 1.1 mmHg (n = 17) for patients switching to latanoprost, and 23.2 +/- 1.0 and 17.5 +/- 0.8 mmHg (n = 17) for patients with combined treatment. Adding latanoprost to timolol reduced IOP with 5.9 +/- 0.9 mmHg (p < 0.001) and switching from timolol to latanoprost reduced IOP with 5.0 +/- 0.9 mmHg (p < 0.001), which caused in each group a significant IOP reduction of about 25%.CONCLUSIONSThe effect of latanoprost was additive to that of timolol, and a good effect on IOP reduction was also achieved by switching from timolol to latanoprost, suggesting that a switch in many patients is an effective alternative to combination treatment.
目的探讨替马洛尔不能有效控制眼压的开角型青光眼或高眼压患者,由替马洛尔改用拉坦前列素或拉坦前列素加替马洛尔对眼压的影响。方法:这是一项为期6周、双盲、随机多中心的研究。53例原发性开角型青光眼、荚膜型青光眼或高眼压患者接受当前治疗,IOP至少为21 mmHg。经过至少2周的替莫洛尔(5mg /ml,每日两次)磨合期后,患者被随机分为三组之一。一组继续使用替洛尔,一组从替洛尔改为拉坦前列素,50微克/毫升,每日一次,第三组在使用替洛尔的同时使用拉坦前列素。通过比较治疗6周后上午9点和基线时的IOP来评估疗效。结果基线时和治疗6周后,继续使用替洛尔的患者(平均+/- SEM)为24.2 +/- 0.9和23.8 +/- 1.0 mmHg (n = 16),改用拉坦前列素的患者为26.3 +/- 1.2和19.6 +/- 1.1 mmHg (n = 17),联合治疗的患者为23.2 +/- 1.0和17.5 +/- 0.8 mmHg (n = 17)。拉坦前列素加替莫洛尔可使IOP降低5.9 +/- 0.9 mmHg (p < 0.001),而由替莫洛尔改用拉坦前列素可使IOP降低5.0 +/- 0.9 mmHg (p < 0.001),两组IOP均显著降低约25%。结论拉坦前列素与替马洛尔的作用是叠加性的,由替马洛尔转为拉坦前列素对降低IOP也有很好的效果,提示许多患者改用拉坦前列素是联合治疗的一种有效选择。
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引用次数: 21
Phacoemulsification and intraocular lens implantation in eyes with open-angle glaucoma. 开角型青光眼的超声乳化术及人工晶体植入术。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790322.X
T. Pohjalainen, E. Vesti, R. Uusitalo, L. Laatikainen
PURPOSETo study the effect of phacoemulsification and intraocular lens implantation (PHACO IOL) on intraocular pressure (IOP) and glaucoma medication in open-angle glaucoma (OAG) eyes.METHODS38 open-angle glaucoma (OAG) eyes with cataract underwent phacoemulsification and intraocular lens implantation (PHACO IOL) performed by one surgeon (RJU). None of the patients had prior intraocular surgery. Surgery was performed by scleral incision on 37% and by clear corneal incision on 63%. Patients were re-examined on the first postoperative day, after one week, 4 months, and in 29 cases 1-3.7 (mean 2.8) years after the operation.RESULTSThe mean preoperative IOP was 18.4+/-3.3 mmHg with a mean of 1.7 glaucoma medications. On the first postoperative day, the mean IOP rose to 28.2 +/- 12.5 mmHg. IOP > or = 30 mmHg occurred in 39.5% of the eyes. After one week, IOP had returned to the preoperative level. After 4 months, IOP had further decreased to 16.1 +/- 3.8 mmHg (p = 0.0027). After a mean follow-up of 1-3.7 (mean 2.8) years, the average postoperative IOP was 15.1 +/- 2.9 mmHg, being significantly (p = 0.001) lower than the preoperative IOP with 86% of the patients having a mean of 1.6 drugs on average. The type of incision (scleral vs. corneal) did not affect the postoperative IOP level. Using the criteria of Bigger and Becker (1971) the long-term IOP control after PHACO-IOL surgery was improved or unchanged in 86% and worse in 14% of the preoperatively well-controlled OAG eyes.CONCLUSIONSIn OAG eyes PHACO IOL is associated with a significant decrease in IOP with less medication up to 1-3.7 (mean 2.8) years.
目的探讨晶状体超声乳化植入术(PHACO IOL)对开角型青光眼(OAG)患者眼压(IOP)及青光眼药物治疗的影响。方法对38例开角型青光眼合并白内障行超声乳化术联合人工晶状体植入术(PHACO IOL)。所有患者均未进行过眼内手术。巩膜切口占37%,角膜透明切口占63%。术后第一天、1周、4个月、29例术后1-3.7年(平均2.8年)复查。结果术前平均IOP为18.4+/-3.3 mmHg,平均1.7种青光眼药物。术后第一天,平均IOP上升至28.2 +/- 12.5 mmHg。39.5%的眼睛眼压低于或等于30 mmHg。一周后,IOP恢复到术前水平。4个月后,IOP进一步下降至16.1 +/- 3.8 mmHg (p = 0.0027)。平均随访1-3.7年(平均2.8年),术后平均IOP为15.1±2.9 mmHg,显著低于术前(p = 0.001), 86%的患者平均使用1.6种药物。切口类型(巩膜或角膜)不影响术后IOP水平。使用Bigger和Becker(1971)的标准,86%的术前控制良好的OAG眼在PHACO-IOL手术后的长期IOP控制得到改善或保持不变,14%的OAG眼的长期IOP控制较差。结论:在OAG眼中,PHACO IOL与IOP显著降低相关,减少用药可达1-3.7年(平均2.8年)。
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引用次数: 97
Costs of medical and surgical treatment of glaucoma. 青光眼的医疗和手术治疗费用。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790315.X
B. Calissendorff
PURPOSETo compare county costs of medical and surgical glaucoma treatment.METHODSMedical records of 470 patients who underwent trabeculectomies in 1992 were scrutinized for a period of 3 years before and 3 years after surgery (including the year of surgery). Treatment costs were based on DRG prices, and drug consumption costs on the "defined daily dose" (DDD).RESULTSThe costs rose steadily during the 3 years before surgery on account of more frequent visits and examinations and increased drug consumption. Mean total cost in the preoperative period was 13,355 SEK and that in the corresponding postoperative period, including surgery, was 23,684 SEK. The number of visits post-surgery was only slightly reduced, but there was a marked decrease in medication. However, the cost of the drugs was not correspondingly lower. Thirty percent of the patients later underwent cataract extraction.CONCLUSIONFrom a strictly economic point of view glaucoma surgery is not profitable within a 3-year postoperative period.
目的比较各县青光眼内科和外科治疗费用。方法对1992年行小梁切除术的470例患者术前、术后3年(包括手术年份)的病历进行回顾性分析。治疗费用以DRG价格为基础,药物消费费用以“限定日剂量”(DDD)为基础。结果术前3年住院费用稳步上升,主要原因是就诊和检查次数增加,药物用量增加。术前平均总费用为13,355瑞典克朗,术后包括手术在内的平均总费用为23,684瑞典克朗。手术后的就诊次数仅略有减少,但药物治疗明显减少。然而,药物的成本并没有相应降低。30%的患者后来接受了白内障摘除手术。结论从严格的经济角度来看,青光眼手术在术后3年内无利可图。
{"title":"Costs of medical and surgical treatment of glaucoma.","authors":"B. Calissendorff","doi":"10.1034/J.1600-0420.2001.790315.X","DOIUrl":"https://doi.org/10.1034/J.1600-0420.2001.790315.X","url":null,"abstract":"PURPOSE\u0000To compare county costs of medical and surgical glaucoma treatment.\u0000\u0000\u0000METHODS\u0000Medical records of 470 patients who underwent trabeculectomies in 1992 were scrutinized for a period of 3 years before and 3 years after surgery (including the year of surgery). Treatment costs were based on DRG prices, and drug consumption costs on the \"defined daily dose\" (DDD).\u0000\u0000\u0000RESULTS\u0000The costs rose steadily during the 3 years before surgery on account of more frequent visits and examinations and increased drug consumption. Mean total cost in the preoperative period was 13,355 SEK and that in the corresponding postoperative period, including surgery, was 23,684 SEK. The number of visits post-surgery was only slightly reduced, but there was a marked decrease in medication. However, the cost of the drugs was not correspondingly lower. Thirty percent of the patients later underwent cataract extraction.\u0000\u0000\u0000CONCLUSION\u0000From a strictly economic point of view glaucoma surgery is not profitable within a 3-year postoperative period.","PeriodicalId":7152,"journal":{"name":"Acta ophthalmologica Scandinavica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89568456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Removal of a large non-functional bleb and reconstruction with free conjunctival autograft after trabeculectomy. 小梁切除术后大的无功能泡的去除和自体结膜自由移植重建。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790326.X
M. Honjo, H. Tanihara, M. Inatani, Y. Honda
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引用次数: 1
Anterior Segment Complications of Contact Lens Wear 隐形眼镜佩戴前段并发症
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790329.X
S. Nilsson
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引用次数: 0
Acute posterior multifocal placoid pigment epitheliopathy and ulcerative colitis: a possible association. 急性后部多灶性placoid色素上皮病与溃疡性结肠炎:可能的关联。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790324.X
L. Di Crecchio, M. Parodi, S. Saviano, G. Ravalico
PURPOSETo report a case of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE) in the course of Ulcerative Colitis (UC).METHODSA complete ophthalmologic evaluation, including fluorescein and indocyanine green angiography, was performed.RESULTSA patient with exacerbation of UC was referred to our department for sudden visual loss in RE. Ophthalmoscopy disclosed multifocal yellow-white placoid lesions typical of APMPPE in RE. There were no lesions in the fellow eye. On fluorescein angiography (FA), the active lesions showed early hypofluorescence, followed by late staining. Indocyanine green angiography (ICGA) revealed early and late hypofluorescence corresponding to the lesions observed clinically, and late anular staining surrounding a hypofluorescent lesion at the posterior pole. On LE ICGA revealed lesions not detected with ophthalmoscopy and FA. After corticosteroid therapy the lesions healed.CONCLUSIONUlcerative Colitis may be responsible for the onset of AMPPPE by an immunological mechanism of delayed type hypersensitivity reaction.
目的报告1例溃疡性结肠炎(UC)病程中出现的急性后部多灶性Placoid Pigment epithelial opathy (APMPPE)。方法采用荧光素和吲哚菁绿血管造影对患者进行全面的眼科检查。结果一名UC加重患者因RE型突发性视力丧失转诊至我科,检出多发黄白色斑块,为典型的RE型APMPPE,伴眼未见病变。在荧光素血管造影(FA)上,活动性病变表现为早期低荧光,随后是晚期染色。吲哚菁绿血管造影(ICGA)显示与临床观察到的病变相对应的早期和晚期低荧光,以及后极低荧光病变周围的晚期环状染色。LE ICGA显示眼底镜和FA未发现的病变。皮质类固醇治疗后病变愈合。结论溃疡性结肠炎可能通过延迟型超敏反应的免疫机制导致AMPPPE的发生。
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引用次数: 21
Macular star associated with posterior hyaloid detachment. 黄斑星型伴后玻璃体脱离。
Pub Date : 2001-06-01 DOI: 10.1034/J.1600-0420.2001.790323.X
J. Akura, T. Ikeda, K. Sato, N. Ikeda
PURPOSETo report a patient with a Leber's idiopathic stellate neuroretinitis-like lesion that was caused by vitreous traction accompanying a posterior hyaloid detachment.METHODSWe present a 49-year-old woman who showed segmental optic disc edema, peripapillary retinal detachment, and a macular star.RESULTSAn incomplete posterior hyaloid detachment was present, and the posterior hyaloid membrane was attached to the nasal margin of the optic disc. Fluorescein angiography revealed a bent retinal artery on the upper margin of the optic disc, and leakage of fluorescein was observed from this area.CONCLUSIONVascular damage to the optic disc due to vitreous traction should also be considered as a mechanism for the ophthalmoscopic appearance of the fundus when lesions suggestive of Leber's idiopathic stellate neuroretinitis are present in an adult.
目的报告一例由玻璃体牵引合并后玻璃体脱离引起的Leber氏特发性星状神经视网膜炎样病变。方法我们报告了一位49岁的女性,她表现为视盘节段性水肿,乳头周围视网膜脱离和黄斑星。结果后玻璃体不完全脱离,后玻璃体膜附着于视盘鼻缘。荧光素血管造影显示视盘上缘有一条弯曲的视网膜动脉,并在该区域观察到荧光素渗漏。结论当成人出现Leber氏特发性星状神经视网膜炎时,玻璃体牵拉引起的视盘血管损伤也应被视为眼底外观的一个机制。
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引用次数: 2
期刊
Acta ophthalmologica Scandinavica
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