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Triage of 2D Mammographic Images Using Multi-view Multi-task Convolutional Neural Networks 基于多视图多任务卷积神经网络的二维乳房x线图像分诊
Pub Date : 2021-07-15 DOI: 10.1145/3453166
T. Kyono, F. Gilbert, M. Schaar
With an aging and growing population, the number of women receiving mammograms is increasing. However, existing techniques for autonomous diagnosis do not surpass a well-trained radiologist. Therefore, to reduce the number of mammograms that require examination by a radiologist, subject to preserving the diagnostic accuracy observed in current clinical practice, we develop Man and Machine Mammography Oracle (MAMMO)—a clinical decision support system capable of determining whether its predicted diagnoses require further radiologist examination. We first introduce a novel multi-view convolutional neural network (CNN) trained using multi-task learning (MTL) to diagnose mammograms and predict the radiological assessments known to be associated with cancer. MTL improves diagnostic performance and triage efficiency while providing an additional layer of model interpretability. Furthermore, we introduce a novel triage network that takes as input the radiological assessment and diagnostic predictions of the multi-view CNN and determines whether the radiologist or CNN will most likely provide the correct diagnosis. Results obtained on a dataset of over 7,000 patients show that MAMMO reduced the number of diagnostic mammograms requiring radiologist reading by 42.8% while improving the overall diagnostic accuracy in comparison to readings done by radiologists alone.
随着人口老龄化和增长,接受乳房X光检查的女性人数正在增加。然而,现有的自主诊断技术并不能超越训练有素的放射科医生。因此,为了减少需要放射科医生检查的乳房X光片数量,在保持当前临床实践中观察到的诊断准确性的前提下,我们开发了人机乳腺X光片Oracle(MAMMO)——一种临床决策支持系统,能够确定其预测诊断是否需要放射科医师进一步检查。我们首先介绍了一种新的多视图卷积神经网络(CNN),该网络使用多任务学习(MTL)进行训练,以诊断乳房X光检查并预测已知与癌症相关的放射学评估。MTL提高了诊断性能和分诊效率,同时提供了额外的模型可解释性层。此外,我们引入了一种新的分诊网络,该网络将多视图CNN的放射学评估和诊断预测作为输入,并确定放射科医生或CNN是否最有可能提供正确的诊断。在7000多名患者的数据集上获得的结果显示,与放射科医生单独读取的数据相比,MAMMO将需要放射科医生读取的诊断性乳房X光照片数量减少了42.8%,同时提高了整体诊断准确性。
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引用次数: 3
A Fast ECG Diagnosis by Using Non-Uniform Spectral Analysis and the Artificial Neural Network 基于非均匀谱分析和人工神经网络的心电快速诊断
Pub Date : 2021-07-15 DOI: 10.1145/3453174
K. Chen, Po-Chen Chien, Zi-Jie Gao, Chi-Hsun Wu
The electrocardiogram (ECG) has been proven as an efficient diagnostic tool to monitor the electrical activity of the heart and has become a widely used clinical approach to diagnose heart diseases. In a practical way, the ECG signal can be decomposed into P, Q, R, S, and T waves. Based on the information of the features in these waves, such as the amplitude and the interval between each wave, many types of heart diseases can be detected by using the neural network (NN)-based ECG analysis approach. However, because of a large amount of computing to preprocess the raw ECG signal, it is time consuming to analyze the ECG signal in the time domain. In addition, the non-linear ECG signal analysis worsens the difficulty to diagnose the ECG signal. To solve the problem, we propose a fast ECG diagnosis approach based on spectral analysis and the artificial neural network. Compared with the conventional time-domain approaches, the proposed approach analyzes the ECG signal only in the frequency domain. However, because most of the noises in the raw ECG signal belong to high-frequency signals, it is necessary to acquire more features in the low-frequency spectrum and fewer features in the high-frequency spectrum. Hence, a non-uniform feature extraction approach is proposed in this article. According to less data preprocessing in the frequency domain than the one in the time domain, the proposed approach not only reduces the total diagnosis latency but also reduces the computing power consumption of the ECG diagnosis. To verify the proposed approach, the well-known MIT-BIH arrhythmia database is involved in this work. The experimental results show that the proposed approach can reduce ECG diagnosis latency by 47% to 52% compared with conventional ECG analysis methods under similar diagnostic accuracy of heart diseases. In addition, because of less data preprocessing, the proposed approach can achieve lower area overhead by 22% to 29% and lower computing power consumption by 29% to 34% compared with the related works, which is proper for applying this approach to portable medical devices.
心电图(ECG)已被证明是监测心脏电活动的有效诊断工具,并已成为诊断心脏病的广泛应用的临床方法。在实际的方式中,ECG信号可以被分解为P、Q、R、S和T波。基于这些波中的特征信息,如每个波的振幅和间隔,可以使用基于神经网络的ECG分析方法来检测多种类型的心脏病。然而,由于对原始ECG信号进行预处理需要大量的计算,因此在时域中分析ECG信号是耗时的。此外,非线性ECG信号分析加剧了ECG信号的诊断难度。为了解决这个问题,我们提出了一种基于频谱分析和人工神经网络的快速心电诊断方法。与传统的时域方法相比,该方法只在频域中分析心电信号。然而,由于原始ECG信号中的大多数噪声属于高频信号,因此需要在低频谱中获取更多的特征,而在高频谱中获取更少的特征。因此,本文提出了一种非均匀特征提取方法。由于频域中的数据预处理少于时域中的数据,该方法不仅降低了总诊断延迟,而且降低了ECG诊断的计算功耗。为了验证所提出的方法,著名的MIT-BIH心律失常数据库参与了这项工作。实验结果表明,在心脏病诊断准确率相似的情况下,与传统的心电图分析方法相比,该方法可以将心电图诊断延迟降低47%至52%。此外,由于数据预处理较少,与相关工作相比,该方法可以实现22%至29%的区域开销和29%至34%的计算功耗,适合将该方法应用于便携式医疗设备。
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引用次数: 2
A Framework for Generating Summaries from Temporal Personal Health Data 从时间个人健康数据生成摘要的框架
Pub Date : 2021-07-15 DOI: 10.1145/3448672
Jon Harris, Ching-Hua Chen, Mohammed J. Zaki
Although it has become easier for individuals to track their personal health data (e.g., heart rate, step count, and nutrient intake data), there is still a wide chasm between the collection of data and the generation of meaningful summaries to help users better understand what their data means to them. With an increased comprehension of their data, users will be able to act upon the newfound information and work toward striving closer to their health goals. We aim to bridge the gap between data collection and summary generation by mining the data for interesting behavioral findings that may provide hints about a user’s tendencies. Our focus is on improving the explainability of temporal personal health data via a set of informative summary templates, or “protoforms.” These protoforms span both evaluation-based summaries that help users evaluate their health goals and pattern-based summaries that explain their implicit behaviors. In addition to individual-level summaries, the protoforms we use are also designed for population-level summaries. We apply our approach to generate summaries (both univariate and multivariate) from real user health data and show that the summaries our system generates are both interesting and useful.
尽管个人追踪个人健康数据(如心率、步数和营养摄入数据)变得更容易了,但在收集数据和生成有意义的摘要以帮助用户更好地理解他们的数据对他们意味着什么之间仍然存在巨大差距。随着对数据的理解程度提高,用户将能够根据新发现的信息采取行动,努力实现他们的健康目标。我们的目标是通过挖掘数据以获得有趣的行为发现,从而弥合数据收集和摘要生成之间的差距,这些行为发现可能会提供有关用户倾向的提示。我们的重点是通过一组信息摘要模板或“原型”来提高时间个人健康数据的可解释性。这些原型既包括帮助用户评估其健康目标的基于评估的摘要,也包括解释其隐性行为的基于模式的摘要。除了个人层面的总结,我们使用的原型也是为群体层面的总结而设计的。我们应用我们的方法从真实的用户健康数据中生成摘要(单变量和多变量),并表明我们的系统生成的摘要既有趣又有用。
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引用次数: 6
Early Detection of Health Changes in the Elderly Using In-Home Multi-Sensor Data Streams 利用家庭多传感器数据流早期检测老年人的健康变化
Pub Date : 2021-07-01 DOI: 10.1145/3448671
Wenlong Wu, J. Keller, M. Skubic, M. Popescu, Kari R. Lane
The rapid aging of the population worldwide requires increased attention from healthcare providers and the entire society. For the elderly to live independently, many health issues related to old age, such as frailty and risk of falling, need increased attention and monitoring. When monitoring daily routines for older adults, it is desirable to detect the early signs of health changes before serious health events, such as hospitalizations, happen so that timely and adequate preventive care may be provided. By deploying multi-sensor systems in homes of the elderly, we can track trajectories of daily behaviors in a feature space defined using the sensor data. In this article, we investigate a methodology for tracking the evolution of the behavior trajectories over long periods (years) using high-dimensional streaming clustering and provide very early indicators of changes in health. If we assume that habitual behaviors correspond to clusters in feature space and diseases produce a change in behavior, albeit not highly specific, tracking trajectory deviations can provide hints of early illness. Retrospectively, we visualize the streaming clustering results and track how the behavior clusters evolve in feature space with the help of two dimension-reduction algorithms: Principal Component Analysis and t-distributed Stochastic Neighbor Embedding. Moreover, our tracking algorithm in the original high-dimensional feature space generates early health warning alerts if a negative trend is detected in the behavior trajectory. We validated our algorithm on synthetic data and tested it on a pilot dataset of four TigerPlace residents monitored with a collection of motion, bed, and depth sensors over 10 years. We used the TigerPlace electronic health records to understand the residents’ behavior patterns and to evaluate the health warnings generated by our algorithm. The results obtained on the TigerPlace dataset show that most of the warnings produced by our algorithm can be linked to health events documented in the electronic health records, providing strong support for a prospective deployment of the approach.
全球人口的快速老龄化需要医疗保健提供者和整个社会更加关注。为了让老年人独立生活,许多与老年有关的健康问题,如虚弱和跌倒风险,需要更多的关注和监测。在监测老年人的日常生活时,最好在发生严重健康事件(如住院)之前发现健康变化的早期迹象,以便提供及时和充分的预防性护理。通过在老年人的家中部署多传感器系统,我们可以在使用传感器数据定义的特征空间中跟踪日常行为的轨迹。在这篇文章中,我们研究了一种使用高维流聚类跟踪长期(多年)行为轨迹演变的方法,并提供了健康变化的早期指标。如果我们假设习惯性行为与特征空间中的集群相对应,并且疾病会导致行为的变化,尽管不是很具体,那么跟踪轨迹偏差可以提供早期疾病的提示。回顾性地,我们借助两种降维算法:主成分分析和t分布随机邻居嵌入,可视化流聚类结果,并跟踪行为聚类在特征空间中的演化。此外,如果在行为轨迹中检测到负面趋势,我们在原始高维特征空间中的跟踪算法会生成早期健康警告警报。我们在合成数据上验证了我们的算法,并在由四名TigerPlace居民组成的试点数据集上进行了测试,该数据集由运动、床和深度传感器组成,历时10年。我们使用TigerPlace电子健康记录来了解居民的行为模式,并评估我们的算法生成的健康警告。在TigerPlace数据集上获得的结果表明,我们的算法产生的大多数警告都可以与电子健康记录中记录的健康事件相关联,为该方法的前瞻性部署提供了强有力的支持。
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引用次数: 7
An Accurate Non-accelerometer-based PPG Motion Artifact Removal Technique using CycleGAN 基于CycleGAN的精确非加速度计PPG运动伪影去除技术
Pub Date : 2021-06-22 DOI: 10.1145/3563949
Amir Hosein Afandizadeh Zargari, S. A. H. Aqajari, Hadi Khodabandeh, A. Rahmani, Fadi J. Kurdahi
A photoplethysmography (PPG) is an uncomplicated and inexpensive optical technique widely used in the healthcare domain to extract valuable health-related information, e.g., heart rate variability, blood pressure, and respiration rate. PPG signals can easily be collected continuously and remotely using portable wearable devices. However, these measuring devices are vulnerable to motion artifacts caused by daily life activities. The most common ways to eliminate motion artifacts use extra accelerometer sensors, which suffer from two limitations: (i) high power consumption, and (ii) the need to integrate an accelerometer sensor in a wearable device (which is not required in certain wearables). This paper proposes a low-power non-accelerometer-based PPG motion artifacts removal method outperforming the accuracy of the existing methods. We use Cycle Generative Adversarial Network to reconstruct clean PPG signals from noisy PPG signals. Our novel machine-learning-based technique achieves 9.5 times improvement in motion artifact removal compared to the state-of-the-art without using extra sensors such as an accelerometer, which leads to 45% improvement in energy efficiency.
光体积描记术(PPG)是一种简单且廉价的光学技术,广泛用于医疗保健领域,以提取有价值的健康相关信息,例如心率变异性、血压和呼吸频率。PPG信号可以使用便携式可穿戴设备轻松地连续和远程收集。然而,这些测量设备容易受到日常生活活动引起的运动伪影的影响。消除运动伪影的最常见方法是使用额外的加速度计传感器,这受到两个限制:(i)高功耗,以及(ii)需要在可穿戴设备中集成加速度计传感器(这在某些可穿戴设备上是不需要的)。本文提出了一种基于低功耗非加速度计的PPG运动伪影去除方法,该方法的精度优于现有方法。我们使用循环生成对抗性网络从噪声PPG信号中重建干净的PPG信号。与不使用加速度计等额外传感器的最先进技术相比,我们新的基于机器学习的技术在去除运动伪影方面实现了9.5倍的改进,从而使能效提高了45%。
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引用次数: 14
Can Chatbots Help Support a Person’s Mental Health? Perceptions and Views from Mental Healthcare Professionals and Experts 聊天机器人能帮助支持一个人的心理健康吗?来自精神保健专业人员和专家的看法和观点
Pub Date : 2021-05-26 DOI: 10.1145/3453175
Colm Sweeney, C. Potts, E. Ennis, Raymond R. Bond, M. Mulvenna, S. O’neill, M. Malcolm, L. Kuosmanen, C. Kostenius, A. Vakaloudis, G. Mcconvey, Robin Turkington, D. Hanna, H. Nieminen, A. Vartiainen, A. Robertson, M. McTear
The objective of this study was to understand the attitudes of professionals who work in mental health regarding the use of conversational user interfaces, or chatbots, to support people’s mental health and wellbeing. This study involves an online survey to measure the awareness and attitudes of mental healthcare professionals and experts. The findings from this survey show that more than half of the participants in the survey agreed that there are benefits associated with mental healthcare chatbots (65%, p < 0.01). The perceived importance of chatbots was also relatively high (74%, p < 0.01), with more than three-quarters (79%, p < 0.01) of respondents agreeing that mental healthcare chatbots could help their clients better manage their own health, yet chatbots are overwhelmingly perceived as not adequately understanding or displaying human emotion (86%, p < 0.01). Even though the level of personal experience with chatbots among professionals and experts in mental health has been quite low, this study shows that where they have been used, the experience has been mostly satisfactory. This study has found that as years of experience increased, there was a corresponding increase in the belief that healthcare chatbots could help clients better manage their own mental health.
本研究的目的是了解从事心理健康工作的专业人员对使用会话用户界面或聊天机器人来支持人们的心理健康和福祉的态度。本研究通过在线调查来衡量心理健康专业人员和专家的意识和态度。这项调查的结果显示,超过一半的调查参与者认为与精神保健聊天机器人相关的好处(65%,p < 0.01)。人们认为聊天机器人的重要性也相对较高(74%,p < 0.01),超过四分之三(79%,p < 0.01)的受访者同意,心理健康聊天机器人可以帮助他们的客户更好地管理自己的健康,但绝大多数人认为聊天机器人不能充分理解或显示人类的情绪(86%,p < 0.01)。尽管专业人士和心理健康专家对聊天机器人的个人体验水平相当低,但这项研究表明,在使用聊天机器人的地方,体验大多令人满意。这项研究发现,随着工作经验的增加,人们越来越相信医疗聊天机器人可以帮助客户更好地管理自己的心理健康。
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引用次数: 43
14 Years of Self-Tracking Technology for mHealth—Literature Review: Lessons Learned and the PAST SELF Framework mHealth自跟踪技术的14年——文献综述:经验教训和PAST Self框架
Pub Date : 2021-04-23 DOI: 10.1145/3592621
Sofia Yfantidou, Pavlos Sermpezis, A. Vakali
In today’s connected society, many people rely on mHealth and self-tracking (ST) technology to help them adopt healthier habits with a focus on breaking their sedentary lifestyle and staying fit. However, there is scarce evidence of such technological interventions’ effectiveness, and there are no standardized methods to evaluate their impact on people’s physical activity and health. This work aims to help ST practitioners and researchers by empowering them with systematic guidelines and a framework for designing and evaluating technological interventions to facilitate health behavior change and user engagement, focusing on increasing physical activity and decreasing sedentariness. To this end, we conduct a literature review of 129 papers between 2008 and 2022, which identifies the core ST design principles and their efficacy, as well as the most comprehensive list to date of user engagement evaluation metrics for ST. Based on the review’s findings, we propose PAST SELF, a framework to guide the design and evaluation of ST technology that has potential applications in industrial and scientific settings. Finally, to facilitate researchers and practitioners, we complement this article with an open corpus and an online, adaptive exploration tool for the PAST SELF data.
在当今互联社会,许多人依靠mHealth和自我跟踪(ST)技术来帮助他们养成更健康的习惯,重点是打破久坐不动的生活方式,保持健康。然而,很少有证据表明这种技术干预措施的有效性,也没有标准化的方法来评估它们对人们身体活动和健康的影响。这项工作旨在帮助ST从业者和研究人员,为他们提供系统的指导方针和设计和评估技术干预措施的框架,以促进健康行为的改变和用户参与,重点是增加体力活动和减少久坐。为此,我们对2008年至2022年间的129篇论文进行了文献综述,确定了ST的核心设计原则及其功效,以及迄今为止最全面的ST用户参与度评估指标列表。基于综述的结果,我们提出了PAST SELF,指导在工业和科学环境中具有潜在应用的ST技术的设计和评估的框架。最后,为了方便研究人员和从业者,我们用一个开放的语料库和一个用于PAST SELF数据的在线自适应探索工具来补充本文。
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引用次数: 3
Security and Privacy Requirements for Electronic Consent 电子同意的安全和隐私要求
Pub Date : 2021-03-21 DOI: 10.1145/3433995
Stef Verreydt, Koen Yskout, W. Joosen
Electronic consent (e-consent) has the potential to solve many paper-based consent approaches. Existing approaches, however, face challenges regarding privacy and security. This literature review aims to provide an overview of privacy and security challenges and requirements proposed by papers discussing e-consent implementations, as well as the manner in which state-of-the-art solutions address them. We conducted a systematic literature search using ACM Digital Library, IEEE Xplore, and PubMed Central. We included papers providing comprehensive discussions of one or more technical aspects of e-consent systems. Thirty-one papers met our inclusion criteria. Two distinct topics were identified, the first being discussions of e-consent representations and the second being implementations of e-consent in data sharing systems. The main challenge for e-consent representations is gathering the requirements for a “valid” consent. For the implementation papers, many provided some requirements but none provided a comprehensive overview. Blockchain is identified as a solution to transparency and trust issues in traditional client-server systems, but several challenges hinder it from being applied in practice. E-consent has the potential to grant data subjects control over their data. However, there is no agreed-upon set of security and privacy requirements that must be addressed by an e-consent platform. Therefore, security- and privacy-by-design techniques should be an essential part of the development lifecycle for such a platform.
电子同意(e-consent)有可能解决许多基于纸张的同意方法。然而,现有方法在隐私和安全方面面临挑战。本文献综述旨在概述讨论电子响应实现的论文提出的隐私和安全挑战和要求,以及最先进的解决方案解决这些问题的方式。我们使用ACM数字图书馆、IEEE Xplore和PubMed Central进行了系统的文献检索。我们收录了对电子响应系统的一个或多个技术方面进行全面讨论的论文。31篇论文符合我们的入选标准。确定了两个不同的主题,第一个是对电子响应表示的讨论,第二个是电子响应在数据共享系统中的实现。电子同意书的主要挑战是收集“有效”同意书的要求。关于实施文件,许多文件提出了一些要求,但没有一份提供全面的概述。区块链被认为是传统客户端-服务器系统中透明度和信任问题的解决方案,但一些挑战阻碍了它在实践中的应用。电子同意有可能授予数据主体对其数据的控制权。然而,没有一套商定的安全和隐私要求必须由电子响应平台解决。因此,设计技术的安全性和隐私性应该是此类平台开发生命周期的重要组成部分。
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引用次数: 5
A Survey of Automatic Contact Tracing Approaches Using Bluetooth Low Energy 蓝牙低能耗自动接触追踪方法综述
Pub Date : 2021-03-17 DOI: 10.1145/3444847
Leonie Reichert, Samuel Brack, B. Scheuermann
To combat the ongoing Covid-19 pandemic, many new ways have been proposed on how to automate the process of finding infected people, also called contact tracing. A special focus was put on preserving the privacy of users. Bluetooth Low Energy as base technology has the most promising properties, so this survey focuses on automated contact tracing techniques using Bluetooth Low Energy. We define multiple classes of methods and identify two major groups: systems that rely on a server for finding new infections and systems that distribute this process. Existing approaches are systematically classified regarding security and privacy criteria.
为了应对持续的新冠肺炎大流行,人们提出了许多新的方法来自动化发现感染者的过程,也被称为接触者追踪。特别注重保护用户的隐私。蓝牙低能耗作为基础技术具有最有前景的特性,因此本调查重点关注使用蓝牙低能耗的自动联系人追踪技术。我们定义了多类方法,并确定了两个主要组:依赖服务器查找新感染的系统和分发此过程的系统。现有方法在安全和隐私标准方面进行了系统分类。
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引用次数: 28
A Survey of Computational Methods for Online Mental State Assessment on Social Media 社交媒体在线心理状态评估计算方法研究
Pub Date : 2021-03-17 DOI: 10.1145/3437259
E. A. Ríssola, D. Losada, F. Crestani
Mental state assessment by analysing user-generated content is a field that has recently attracted considerable attention. Today, many people are increasingly utilising online social media platforms to share their feelings and moods. This provides a unique opportunity for researchers and health practitioners to proactively identify linguistic markers or patterns that correlate with mental disorders such as depression, schizophrenia or suicide behaviour. This survey describes and reviews the approaches that have been proposed for mental state assessment and identification of disorders using online digital records. The presented studies are organised according to the assessment technology and the feature extraction process conducted. We also present a series of studies which explore different aspects of the language and behaviour of individuals suffering from mental disorders, and discuss various aspects related to the development of experimental frameworks. Furthermore, ethical considerations regarding the treatment of individuals’ data are outlined. The main contributions of this survey are a comprehensive analysis of the proposed approaches for online mental state assessment on social media, a structured categorisation of the methods according to their design principles, lessons learnt over the years and a discussion on possible avenues for future research.
通过分析用户生成的内容来评估心理状态是最近引起相当关注的一个领域。如今,许多人越来越多地利用在线社交媒体平台来分享他们的感受和情绪。这为研究人员和卫生从业人员提供了一个独特的机会,可以主动识别与抑郁症、精神分裂症或自杀行为等精神障碍相关的语言标记或模式。本调查描述和回顾了已经提出的使用在线数字记录进行精神状态评估和疾病识别的方法。本文的研究是根据评估技术和特征提取过程进行的。我们还提出了一系列研究,这些研究探讨了精神障碍患者的语言和行为的不同方面,并讨论了与实验框架发展相关的各个方面。此外,还概述了有关个人数据处理的道德考虑。本调查的主要贡献是对社交媒体在线心理状态评估的拟议方法进行全面分析,根据其设计原则对方法进行结构化分类,多年来吸取的经验教训以及对未来研究可能途径的讨论。
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引用次数: 32
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ACM transactions on computing for healthcare
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