首页 > 最新文献

ACM transactions on computing for healthcare最新文献

英文 中文
Enhancing Robust Liver Cancer Diagnosis: A Contrastive Multi-Modality Learner with Lightweight Fusion and Effective Data Augmentation 增强肝癌诊断的鲁棒性:具有轻量级融合和有效数据增强功能的多模态对比学习器
Pub Date : 2023-12-30 DOI: 10.1145/3639414
Pei-Xuan Li, Hsun-Ping Hsieh, Chiang Fan Yang, Ding-You Wu, Ching-Chung Ko
This paper explores the application of self-supervised contrastive learning in the medical domain, focusing on classification of multi-modality Magnetic Resonance (MR) images. To address the challenges of limited and hard-to-annotate medical data, we introduce multi-modality data augmentation (MDA) and cross-modality group convolution (CGC). In the pre-training phase, we leverage Simple Siamese networks to maximize the similarity between two augmented MR images from a patient, without a handcrafted pretext task. Our approach also combines 3D and 2D group convolution with a channel shuffle operation to efficiently incorporate different modalities of image features. Evaluation on liver MR images from a well-known hospital in Taiwan demonstrates a significant improvement over previous methods. This work contributes to advancing multi-modality contrastive learning, particularly in the context of medical imaging, offering enhanced tools for analyzing complex image data.
本文探讨了自监督对比学习在医疗领域的应用,重点是多模态磁共振(MR)图像的分类。为了应对医疗数据有限且难以标注的挑战,我们引入了多模态数据增强(MDA)和跨模态群卷积(CGC)。在预训练阶段,我们利用简单连体网络(Simple Siamese networks)来最大化患者两幅增强磁共振图像之间的相似性,而无需手工制作借口任务。我们的方法还将三维和二维群卷积与通道洗牌操作相结合,有效地整合了不同模式的图像特征。在台湾一家知名医院的肝脏磁共振图像上进行的评估表明,我们的方法比以前的方法有了显著的改进。这项工作有助于推进多模态对比学习,尤其是在医学成像方面,为分析复杂图像数据提供了更强大的工具。
{"title":"Enhancing Robust Liver Cancer Diagnosis: A Contrastive Multi-Modality Learner with Lightweight Fusion and Effective Data Augmentation","authors":"Pei-Xuan Li, Hsun-Ping Hsieh, Chiang Fan Yang, Ding-You Wu, Ching-Chung Ko","doi":"10.1145/3639414","DOIUrl":"https://doi.org/10.1145/3639414","url":null,"abstract":"This paper explores the application of self-supervised contrastive learning in the medical domain, focusing on classification of multi-modality Magnetic Resonance (MR) images. To address the challenges of limited and hard-to-annotate medical data, we introduce multi-modality data augmentation (MDA) and cross-modality group convolution (CGC). In the pre-training phase, we leverage Simple Siamese networks to maximize the similarity between two augmented MR images from a patient, without a handcrafted pretext task. Our approach also combines 3D and 2D group convolution with a channel shuffle operation to efficiently incorporate different modalities of image features. Evaluation on liver MR images from a well-known hospital in Taiwan demonstrates a significant improvement over previous methods. This work contributes to advancing multi-modality contrastive learning, particularly in the context of medical imaging, offering enhanced tools for analyzing complex image data.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":" 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139140053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subsampled Randomized Hadamard Transformation based Ensemble Extreme Learning Machine for Human Activity Recognition 基于子采样随机哈达玛变换的集合极限学习机用于人类活动识别
Pub Date : 2023-11-27 DOI: 10.1145/3634813
Dipanwita Thakur, Arindam Pal
Extreme Learning Machine (ELM) is becoming a popular learning algorithm due to its diverse applications, including Human Activity Recognition (HAR). In ELM, the hidden node parameters are generated at random, and the output weights are computed analytically. However, even with a large number of hidden nodes, feature learning using ELM may not be efficient for natural signals due to its shallow architecture. Due to noisy signals of the smartphone sensors and high dimensional data, substantial feature engineering is required to obtain discriminant features and address the “curse-of-dimensionality”. In traditional ML approaches, dimensionality reduction and classification are two separate and independent tasks, increasing the system’s computational complexity. This research proposes a new ELM-based ensemble learning framework for human activity recognition to overcome this problem. The proposed architecture consists of two key parts: 1) Self-taught dimensionality reduction followed by classification. 2) they are bridged by “Subsampled Randomized Hadamard Transformation” (SRHT). Two different HAR datasets are used to establish the feasibility of the proposed framework. The experimental results clearly demonstrate the superiority of our method over the current state-of-the-art methods.
极限学习机(ELM)因其广泛的应用而成为一种流行的学习算法,包括人类活动识别(HAR)。在 ELM 中,隐藏节点的参数是随机生成的,输出权重是通过分析计算得出的。然而,即使有大量的隐藏节点,由于其架构较浅,使用 ELM 进行特征学习对于自然信号可能并不有效。由于智能手机传感器信号嘈杂,数据维度高,因此需要大量的特征工程来获取判别特征,解决 "维度诅咒 "问题。在传统的 ML 方法中,降维和分类是两个独立的任务,增加了系统的计算复杂度。为克服这一问题,本研究提出了一种新的基于 ELM 的人类活动识别集合学习框架。建议的架构由两个关键部分组成:1)自学降维,然后是分类。2)通过 "子采样随机哈达玛变换"(SRHT)将它们连接起来。我们使用了两个不同的 HAR 数据集来确定所提框架的可行性。实验结果清楚地证明了我们的方法优于目前最先进的方法。
{"title":"Subsampled Randomized Hadamard Transformation based Ensemble Extreme Learning Machine for Human Activity Recognition","authors":"Dipanwita Thakur, Arindam Pal","doi":"10.1145/3634813","DOIUrl":"https://doi.org/10.1145/3634813","url":null,"abstract":"Extreme Learning Machine (ELM) is becoming a popular learning algorithm due to its diverse applications, including Human Activity Recognition (HAR). In ELM, the hidden node parameters are generated at random, and the output weights are computed analytically. However, even with a large number of hidden nodes, feature learning using ELM may not be efficient for natural signals due to its shallow architecture. Due to noisy signals of the smartphone sensors and high dimensional data, substantial feature engineering is required to obtain discriminant features and address the “curse-of-dimensionality”. In traditional ML approaches, dimensionality reduction and classification are two separate and independent tasks, increasing the system’s computational complexity. This research proposes a new ELM-based ensemble learning framework for human activity recognition to overcome this problem. The proposed architecture consists of two key parts: 1) Self-taught dimensionality reduction followed by classification. 2) they are bridged by “Subsampled Randomized Hadamard Transformation” (SRHT). Two different HAR datasets are used to establish the feasibility of the proposed framework. The experimental results clearly demonstrate the superiority of our method over the current state-of-the-art methods.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139229816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Smart Insoles for Recognition of Activities of Daily Living: A Systematic Review 应用智能鞋垫识别日常生活活动:系统回顾
Pub Date : 2023-11-24 DOI: 10.1145/3633785
Luigi D’Arco, Graham McCalmont, Haiying Wang, Huiru Zheng
Recent years have witnessed the increasing literature on using smart insoles in health and well-being, and yet, their capability of daily living activity recognition has not been reviewed. This paper addressed this need and provided a systematic review of smart insole-based systems in the recognition of Activities of Daily Living (ADLs). The review followed the PRISMA guidelines, assessing the sensing elements used, the participants involved, the activities recognised, and the algorithms employed. The findings demonstrate the feasibility of using smart insoles for recognising ADLs, showing their high performance in recognising ambulation and physical activities involving the lower body, ranging from 70% to 99.8% of Accuracy, with 13 studies over 95%. The preferred solutions have been those including machine learning. A lack of existing publicly available datasets has been identified, and the majority of the studies were conducted in controlled environments. Furthermore, no studies assessed the impact of different sampling frequencies during data collection, and a trade-off between comfort and performance has been identified between the solutions. In conclusion, real-life applications were investigated showing the benefits of smart insoles over other solutions and placing more emphasis on the capabilities of smart insoles.
近年来,有关智能鞋垫在健康和福祉领域应用的文献越来越多,然而,有关其日常生活活动识别能力的研究却鲜有问世。本文针对这一需求,对基于智能鞋垫的日常生活活动(ADL)识别系统进行了系统综述。综述遵循了 PRISMA 准则,评估了所使用的传感元件、参与人员、所识别的活动以及所采用的算法。研究结果表明了使用智能鞋垫识别日常生活活动的可行性,显示了智能鞋垫在识别涉及下半身的行走和体力活动方面的高性能,准确率从 70% 到 99.8%,其中有 13 项研究的准确率超过 95%。包括机器学习在内的解决方案一直是首选。目前已发现缺乏公开可用的数据集,而且大多数研究都是在受控环境中进行的。此外,没有研究对数据采集过程中不同采样频率的影响进行评估,而且在各种解决方案之间还存在舒适度和性能之间的权衡问题。总之,对实际应用的调查显示了智能鞋垫相对于其他解决方案的优势,并更加强调了智能鞋垫的功能。
{"title":"Application of Smart Insoles for Recognition of Activities of Daily Living: A Systematic Review","authors":"Luigi D’Arco, Graham McCalmont, Haiying Wang, Huiru Zheng","doi":"10.1145/3633785","DOIUrl":"https://doi.org/10.1145/3633785","url":null,"abstract":"Recent years have witnessed the increasing literature on using smart insoles in health and well-being, and yet, their capability of daily living activity recognition has not been reviewed. This paper addressed this need and provided a systematic review of smart insole-based systems in the recognition of Activities of Daily Living (ADLs). The review followed the PRISMA guidelines, assessing the sensing elements used, the participants involved, the activities recognised, and the algorithms employed. The findings demonstrate the feasibility of using smart insoles for recognising ADLs, showing their high performance in recognising ambulation and physical activities involving the lower body, ranging from 70% to 99.8% of Accuracy, with 13 studies over 95%. The preferred solutions have been those including machine learning. A lack of existing publicly available datasets has been identified, and the majority of the studies were conducted in controlled environments. Furthermore, no studies assessed the impact of different sampling frequencies during data collection, and a trade-off between comfort and performance has been identified between the solutions. In conclusion, real-life applications were investigated showing the benefits of smart insoles over other solutions and placing more emphasis on the capabilities of smart insoles.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"49 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139239470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining Deep Learning with Signal-image Encoding for Multi-Modal Mental Wellbeing Classification 结合深度学习和信号-图像编码的多模态心理健康分类
Pub Date : 2023-11-03 DOI: 10.1145/3631618
Kieran Woodward, Eiman Kanjo, Athanasios Tsanas
The quantification of emotional states is an important step to understanding wellbeing. Time series data from multiple modalities such as physiological and motion sensor data have proven to be integral for measuring and quantifying emotions. Monitoring emotional trajectories over long periods of time inherits some critical limitations in relation to the size of the training data. This shortcoming may hinder the development of reliable and accurate machine learning models. To address this problem, this paper proposes a framework to tackle the limitation in performing emotional state recognition: 1) encoding time series data into coloured images; 2) leveraging pre-trained object recognition models to apply a Transfer Learning (TL) approach using the images from step 1; 3) utilising a 1D Convolutional Neural Network (CNN) to perform emotion classification from physiological data; 4) concatenating the pre-trained TL model with the 1D CNN. We demonstrate that model performance when inferring real-world wellbeing rated on a 5-point Likert scale can be enhanced using our framework, resulting in up to 98.5% accuracy, outperforming a conventional CNN by 4.5%. Subject-independent models using the same approach resulted in an average of 72.3% accuracy (SD 0.038). The proposed methodology helps improve performance and overcome problems with small training datasets.
情绪状态的量化是理解幸福的重要一步。来自多种模式的时间序列数据,如生理和运动传感器数据,已被证明是测量和量化情绪的组成部分。长时间监测情绪轨迹继承了一些与训练数据大小有关的关键限制。这个缺点可能会阻碍可靠和准确的机器学习模型的发展。为了解决这一问题,本文提出了一个框架来解决执行情绪状态识别的局限性:1)将时间序列数据编码为彩色图像;2)利用预训练的对象识别模型,使用第1步的图像应用迁移学习(TL)方法;3)利用一维卷积神经网络(CNN)对生理数据进行情绪分类;4)将预训练的TL模型与1D CNN拼接。我们证明,使用我们的框架可以提高模型在推断5点李克特量表上的真实世界幸福感时的表现,准确率高达98.5%,比传统的CNN高出4.5%。使用相同方法的受试者独立模型的平均准确率为72.3% (SD 0.038)。所提出的方法有助于提高性能并克服小型训练数据集的问题。
{"title":"Combining Deep Learning with Signal-image Encoding for Multi-Modal Mental Wellbeing Classification","authors":"Kieran Woodward, Eiman Kanjo, Athanasios Tsanas","doi":"10.1145/3631618","DOIUrl":"https://doi.org/10.1145/3631618","url":null,"abstract":"The quantification of emotional states is an important step to understanding wellbeing. Time series data from multiple modalities such as physiological and motion sensor data have proven to be integral for measuring and quantifying emotions. Monitoring emotional trajectories over long periods of time inherits some critical limitations in relation to the size of the training data. This shortcoming may hinder the development of reliable and accurate machine learning models. To address this problem, this paper proposes a framework to tackle the limitation in performing emotional state recognition: 1) encoding time series data into coloured images; 2) leveraging pre-trained object recognition models to apply a Transfer Learning (TL) approach using the images from step 1; 3) utilising a 1D Convolutional Neural Network (CNN) to perform emotion classification from physiological data; 4) concatenating the pre-trained TL model with the 1D CNN. We demonstrate that model performance when inferring real-world wellbeing rated on a 5-point Likert scale can be enhanced using our framework, resulting in up to 98.5% accuracy, outperforming a conventional CNN by 4.5%. Subject-independent models using the same approach resulted in an average of 72.3% accuracy (SD 0.038). The proposed methodology helps improve performance and overcome problems with small training datasets.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"41 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135818871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Picture of Factors Affecting User Willingness to Use Mobile Health Applications 影响用户使用移动健康应用程序意愿的因素的综合图片
Pub Date : 2023-10-10 DOI: 10.1145/3626962
Shaojing Fan, Ramesh C. Jain, Mohan S. Kankanhalli
Mobile health (mHealth) applications have become increasingly valuable in preventive healthcare and in reducing the burden on healthcare organizations. The aim of this paper is to investigate the factors that influence user acceptance of mHealth apps and identify the underlying structure that shapes users’ behavioral intention. An online study that employed factorial survey design with vignettes was conducted, and a total of 1,669 participants from eight countries across four continents were included in the study. Structural equation modeling was employed to quantitatively assess how various factors collectively contribute to users’ willingness to use mHealth apps. The results indicate that users’ digital literacy has the strongest impact on their willingness to use them, followed by their online habit of sharing personal information. Users’ concerns about personal privacy only had a weak impact. Furthermore, users’ demographic background, such as their country of residence, age, ethnicity, and education, has a significant moderating effect. Our findings have implications for app designers, healthcare practitioners, and policymakers. Efforts are needed to regulate data collection and sharing and promote digital literacy among the general population to facilitate the widespread adoption of mHealth apps.
移动医疗(mHealth)应用程序在预防性医疗保健和减轻医疗保健组织负担方面变得越来越有价值。本文的目的是调查影响用户接受移动健康应用程序的因素,并确定塑造用户行为意图的底层结构。采用因子调查设计和小插图进行了一项在线研究,来自四大洲八个国家的1,669名参与者被纳入研究。结构方程模型用于定量评估各种因素如何共同影响用户使用移动健康应用程序的意愿。结果表明,用户的数字素养对其使用意愿的影响最大,其次是他们分享个人信息的在线习惯。用户对个人隐私的担忧只产生了微弱的影响。此外,用户的人口统计背景,如他们的居住国、年龄、种族和教育程度,具有显著的调节作用。我们的研究结果对应用程序设计师、医疗从业者和政策制定者具有启示意义。需要努力规范数据收集和共享,并促进普通民众的数字素养,以促进移动健康应用程序的广泛采用。
{"title":"A Comprehensive Picture of Factors Affecting User Willingness to Use Mobile Health Applications","authors":"Shaojing Fan, Ramesh C. Jain, Mohan S. Kankanhalli","doi":"10.1145/3626962","DOIUrl":"https://doi.org/10.1145/3626962","url":null,"abstract":"Mobile health (mHealth) applications have become increasingly valuable in preventive healthcare and in reducing the burden on healthcare organizations. The aim of this paper is to investigate the factors that influence user acceptance of mHealth apps and identify the underlying structure that shapes users’ behavioral intention. An online study that employed factorial survey design with vignettes was conducted, and a total of 1,669 participants from eight countries across four continents were included in the study. Structural equation modeling was employed to quantitatively assess how various factors collectively contribute to users’ willingness to use mHealth apps. The results indicate that users’ digital literacy has the strongest impact on their willingness to use them, followed by their online habit of sharing personal information. Users’ concerns about personal privacy only had a weak impact. Furthermore, users’ demographic background, such as their country of residence, age, ethnicity, and education, has a significant moderating effect. Our findings have implications for app designers, healthcare practitioners, and policymakers. Efforts are needed to regulate data collection and sharing and promote digital literacy among the general population to facilitate the widespread adoption of mHealth apps.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inter-Beat Interval Estimation with Tiramisu Model: A Novel Approach with Reduced Error 用提拉米苏模型估计拍间间隔:一种误差小的新方法
Pub Date : 2023-10-06 DOI: 10.1145/3616020
Asiful Arefeen, Ali Akbari, Seyed Iman Mirzadeh, Roozbeh Jafari, Behrooz A. Shirazi, Hassan Ghasemzadeh
Inter-beat interval (IBI) measurement enables estimation of heart-tare variability (HRV) which, in turns, can provide early indication of potential cardiovascular diseases (CVDs). However, extracting IBIs from noisy signals is challenging since the morphology of the signal gets distorted in the presence of noise. Electrocardiogram (ECG) of a person in heavy motion is highly corrupted with noise, known as motion-artifact, and IBI extracted from it is inaccurate. As a part of remote health monitoring and wearable system development, denoising ECG signals and estimating IBIs correctly from them have become an emerging topic among signal-processing researchers. Apart from conventional methods, deep-learning techniques have been successfully used in signal denoising recently, and diagnosis process has become easier, leading to accuracy levels that were previously unachievable. We propose a deep-learning approach leveraging tiramisu autoencoder model to suppress motion-artifact noise and make the R-peaks of the ECG signal prominent even in the presence of high-intensity motion. After denoising, IBIs are estimated more accurately expediting diagnosis tasks. Results illustrate that our method enables IBI estimation from noisy ECG signals with SNR up to -30dB with average root mean square error (RMSE) of 13 milliseconds for estimated IBIs. At this noise level, our error percentage remains below 8% and outperforms other state of the art techniques.
心跳间隔(IBI)测量可以估计心脏变异性(HRV),进而可以提供潜在心血管疾病(cvd)的早期指示。然而,从噪声信号中提取ibi是具有挑战性的,因为信号的形态在噪声的存在下会被扭曲。人体剧烈运动时的心电图受到噪声的严重干扰,被称为运动伪影,从中提取的IBI是不准确的。作为远程健康监测和可穿戴系统开发的一部分,心电信号去噪和正确估计ibi已成为信号处理研究的新兴课题。除传统方法外,深度学习技术最近已成功用于信号去噪,并且诊断过程变得更加容易,从而达到以前无法实现的精度水平。我们提出了一种利用提拉米苏自编码器模型的深度学习方法来抑制运动伪影噪声,并使心电信号的r峰即使在高强度运动存在时也能突出。去噪后,ibi的估计更准确,加快了诊断任务。结果表明,我们的方法能够从噪声心电信号中估计IBI,信噪比高达-30dB,估计IBI的平均均方根误差(RMSE)为13毫秒。在这种噪声水平下,我们的错误率保持在8%以下,优于其他最先进的技术。
{"title":"Inter-Beat Interval Estimation with Tiramisu Model: A Novel Approach with Reduced Error","authors":"Asiful Arefeen, Ali Akbari, Seyed Iman Mirzadeh, Roozbeh Jafari, Behrooz A. Shirazi, Hassan Ghasemzadeh","doi":"10.1145/3616020","DOIUrl":"https://doi.org/10.1145/3616020","url":null,"abstract":"Inter-beat interval (IBI) measurement enables estimation of heart-tare variability (HRV) which, in turns, can provide early indication of potential cardiovascular diseases (CVDs). However, extracting IBIs from noisy signals is challenging since the morphology of the signal gets distorted in the presence of noise. Electrocardiogram (ECG) of a person in heavy motion is highly corrupted with noise, known as motion-artifact, and IBI extracted from it is inaccurate. As a part of remote health monitoring and wearable system development, denoising ECG signals and estimating IBIs correctly from them have become an emerging topic among signal-processing researchers. Apart from conventional methods, deep-learning techniques have been successfully used in signal denoising recently, and diagnosis process has become easier, leading to accuracy levels that were previously unachievable. We propose a deep-learning approach leveraging tiramisu autoencoder model to suppress motion-artifact noise and make the R-peaks of the ECG signal prominent even in the presence of high-intensity motion. After denoising, IBIs are estimated more accurately expediting diagnosis tasks. Results illustrate that our method enables IBI estimation from noisy ECG signals with SNR up to -30dB with average root mean square error (RMSE) of 13 milliseconds for estimated IBIs. At this noise level, our error percentage remains below 8% and outperforms other state of the art techniques.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"298 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135302162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Phenotyping with an Outcomes-driven Mixture of Experts for Patient Matching and Risk Estimation. 基于结果驱动的患者匹配和风险评估专家混合的临床表型
Pub Date : 2023-10-01 Epub Date: 2023-09-13 DOI: 10.1145/3616021
Nathan C Hurley, Sanket S Dhruva, Nihar R Desai, Joseph R Ross, Che G Ngufor, Frederick Masoudi, Harlan M Krumholz, Bobak J Mortazavi

Observational medical data present unique opportunities for analysis of medical outcomes and treatment decision making. However, because these datasets do not contain the strict pairing of randomized control trials, matching techniques are to draw comparisons among patients. A key limitation to such techniques is verification that the variables used to model treatment decision making are also relevant in identifying the risk of major adverse events. This article explores a deep mixture of experts approach to jointly learn how to match patients and model the risk of major adverse events in patients. Although trained with information regarding treatment and outcomes, after training, the proposed model is decomposable into a network that clusters patients into phenotypes from information available before treatment. This model is validated on a dataset of patients with acute myocardial infarction complicated by cardiogenic shock. The mixture of experts approach can predict the outcome of mortality with an area under the receiver operating characteristic curve of 0.85 ± 0.01 while jointly discovering five potential phenotypes of interest. The technique and interpretation allow for identifying clinically relevant phenotypes that may be used both for outcomes modeling as well as potentially evaluating individualized treatment effects.

观察性医学数据为分析医疗结果和治疗决策提供了独特的机会。然而,由于这些数据集不包含随机对照试验的严格配对,配对技术是为了在患者之间进行比较。这种技术的一个关键限制是验证用于模拟治疗决策的变量也与确定主要不良事件的风险相关。本文探讨了一种深度混合的专家方法,共同学习如何匹配患者并模拟患者主要不良事件的风险。虽然训练了有关治疗和结果的信息,但在训练之后,所提出的模型可分解成一个网络,该网络根据治疗前可用的信息将患者聚类为表型。该模型在急性心肌梗死合并心源性休克患者的数据集上得到了验证。专家混合法在共同发现5种潜在感兴趣表型的同时,预测死亡率的结果在受试者工作特征曲线下的面积为0.85±0.01。该技术和解释允许识别临床相关表型,这些表型可用于结果建模以及潜在的评估个体化治疗效果。
{"title":"Clinical Phenotyping with an Outcomes-driven Mixture of Experts for Patient Matching and Risk Estimation.","authors":"Nathan C Hurley, Sanket S Dhruva, Nihar R Desai, Joseph R Ross, Che G Ngufor, Frederick Masoudi, Harlan M Krumholz, Bobak J Mortazavi","doi":"10.1145/3616021","DOIUrl":"10.1145/3616021","url":null,"abstract":"<p><p>Observational medical data present unique opportunities for analysis of medical outcomes and treatment decision making. However, because these datasets do not contain the strict pairing of randomized control trials, matching techniques are to draw comparisons among patients. A key limitation to such techniques is verification that the variables used to model treatment decision making are also relevant in identifying the risk of major adverse events. This article explores a deep mixture of experts approach to jointly learn how to match patients and model the risk of major adverse events in patients. Although trained with information regarding treatment and outcomes, after training, the proposed model is decomposable into a network that clusters patients into phenotypes from information available before treatment. This model is validated on a dataset of patients with acute myocardial infarction complicated by cardiogenic shock. The mixture of experts approach can predict the outcome of mortality with an area under the receiver operating characteristic curve of 0.85 ± 0.01 while jointly discovering five potential phenotypes of interest. The technique and interpretation allow for identifying clinically relevant phenotypes that may be used both for outcomes modeling as well as potentially evaluating individualized treatment effects.</p>","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":" ","pages":"1-18"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46461728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality-Guaranteed and Cost-Effective Population Health Profiling: A Deep Active Learning Approach 质量保证和成本效益的人口健康分析:一种深度主动学习方法
Pub Date : 2023-08-25 DOI: 10.1145/3617179
Long Chen, Jiangtao Wang, P. Thakuriah
Reliability and cost are two primary consideration for profiling population-scale prevalence (PPP) of multiple None Communicable Diseases (NCDs). In this paper, we exploit intra-disease and inter-disease correlation in different traditionally-sensed-areas (TS-A) to reduce the required number of the profiling task allocated without compromising the data reliability. Specifically, we propose a novel approach called Compressive Population Health TS-A Selection (CPH-TS), which blends the state-of-the-art profile inference, data augmentation and active learning in a unified deep learning framework. It can actively select a minimum number of TS-A regions for profiling task allocation in each profiling cycle, while deducting of the missing data of the unprofiled regions with a probabilistic guarantee of reliability. We evaluate our approach on real-world prevalence datasets of London, which shows the effectiveness of CPH-TS. In general, CPH-TS assigned 11.1-27.3% fewer tasks than baselines, assigning tasks to only 34.7% of the sub-regions while the profiling error below 5% for 95% of the cycles.
可靠性和成本是分析多种非传染性疾病(NCDs)人群规模流行率(PPP)的两个主要考虑因素。在本文中,我们利用不同传统感知区域(TS-A)中的疾病内和疾病间相关性,在不影响数据可靠性的情况下减少所需的分析任务分配数量。具体而言,我们提出了一种称为压缩群体健康TS-a选择(CPH-TS)的新方法,该方法在统一的深度学习框架中融合了最先进的简档推断、数据增强和主动学习。它可以在每个评测周期中主动选择最小数量的TS-a区域用于评测任务分配,同时扣除未编译区域的缺失数据,并具有可靠性的概率保证。我们在伦敦真实世界的流行率数据集上评估了我们的方法,这表明了CPH-TS的有效性。总的来说,CPH-TS分配的任务比基线少11.1-27.3%,仅分配给34.7%的子区域,而95%的周期的分析误差低于5%。
{"title":"Quality-Guaranteed and Cost-Effective Population Health Profiling: A Deep Active Learning Approach","authors":"Long Chen, Jiangtao Wang, P. Thakuriah","doi":"10.1145/3617179","DOIUrl":"https://doi.org/10.1145/3617179","url":null,"abstract":"Reliability and cost are two primary consideration for profiling population-scale prevalence (PPP) of multiple None Communicable Diseases (NCDs). In this paper, we exploit intra-disease and inter-disease correlation in different traditionally-sensed-areas (TS-A) to reduce the required number of the profiling task allocated without compromising the data reliability. Specifically, we propose a novel approach called Compressive Population Health TS-A Selection (CPH-TS), which blends the state-of-the-art profile inference, data augmentation and active learning in a unified deep learning framework. It can actively select a minimum number of TS-A regions for profiling task allocation in each profiling cycle, while deducting of the missing data of the unprofiled regions with a probabilistic guarantee of reliability. We evaluate our approach on real-world prevalence datasets of London, which shows the effectiveness of CPH-TS. In general, CPH-TS assigned 11.1-27.3% fewer tasks than baselines, assigning tasks to only 34.7% of the sub-regions while the profiling error below 5% for 95% of the cycles.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48039644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Deep Learning-based PPG Quality Assessment Approach for Heart Rate and Heart Rate Variability 基于深度学习的心率和心率变异性的PPG质量评估方法
Pub Date : 2023-08-23 DOI: 10.1145/3616019
Emad Kasaeyan Naeini, Fatemeh Sarhaddi, I. Azimi, P. Liljeberg, N. Dutt, A. Rahmani
Photoplethysmography (PPG) is a non-invasive optical method to acquire various vital signs, including heart rate (HR) and heart rate variability (HRV). The PPG method is highly susceptible to motion artifacts and environmental noise. Unfortunately, such artifacts are inevitable in ubiquitous health monitoring, as the users are involved in various activities in their daily routines. Such low-quality PPG signals negatively impact the accuracy of the extracted health parameters, leading to inaccurate decision-making. PPG-based health monitoring necessitates a quality assessment approach to determine the signal quality according to the accuracy of the health parameters. Different studies have thus far introduced PPG signal quality assessment methods, exploiting various indicators and machine learning algorithms. These methods differentiate reliable and unreliable signals, considering morphological features of the PPG signal and focusing on the cardiac cycles. Therefore, they can be utilized for HR detection applications. However, they do not apply to HRV, as only having an acceptable shape is insufficient, and other signal factors may also affect the accuracy. In this paper, we propose a deep learning-based PPG quality assessment method for HR and various HRV parameters. We employ one customized one-dimensional (1D) and three two-dimensional (2D) Convolutional Neural Networks (CNN) to train models for each parameter. Reliability of each of these parameters will be evaluated against the corresponding electrocardiogram signal, using 210 hours of data collected from a home-based health monitoring application. Our results show that the proposed 1D CNN method outperforms the other 2D CNN approaches. Our 1D CNN model obtains the accuracy of 95.63%, 96.71%, 91.42%, 94.01%, and 94.81% for the HR, average of normal to normal interbeat (NN) intervals (AVNN), root mean square of successive NN interval differences (RMSSD), standard deviation of NN intervals (SDNN), and ratio of absolute power in low frequency to absolute power in high frequency (LF/HF) ratios, respectively. Moreover, we compare the performance of our proposed method with state-of-the-art algorithms. We compare our best models for HR-HRV health parameters with six different state-of-the-art PPG signal quality assessment methods. Our results indicate that the proposed method performs better than the other methods. We also provide the open-source model implemented in Python for the community to be integrated into their solutions.
Photoplethysmography (PPG)是一种非侵入性的光学方法,可获取各种生命体征,包括心率(HR)和心率变异性(HRV)。该方法极易受到运动伪影和环境噪声的影响。不幸的是,由于用户在日常生活中涉及各种活动,因此在无处不在的健康监测中,此类工件是不可避免的。这种低质量的PPG信号对提取健康参数的准确性产生负面影响,导致决策不准确。基于ppg的健康监测需要一种质量评估方法,根据健康参数的准确性来确定信号质量。迄今为止,不同的研究引入了PPG信号质量评估方法,利用了各种指标和机器学习算法。这些方法区分可靠和不可靠的信号,考虑到PPG信号的形态学特征,并关注心脏周期。因此,它们可以用于人力资源检测应用。然而,它们不适用于HRV,因为只有可接受的形状是不够的,其他信号因素也可能影响精度。在本文中,我们提出了一种基于深度学习的HR和各种HRV参数的PPG质量评估方法。我们使用一个定制的一维(1D)和三个二维(2D)卷积神经网络(CNN)来训练每个参数的模型。每个参数的可靠性将根据相应的心电图信号进行评估,使用从家庭健康监测应用程序收集的210小时数据。我们的结果表明,所提出的一维CNN方法优于其他二维CNN方法。我们的1D CNN模型在HR、正态与正态间隔(NN)均值(AVNN)、连续NN间隔差的均方根(RMSSD)、NN间隔标准差(SDNN)和低频绝对功率与高频绝对功率之比(LF/HF)方面的准确率分别为95.63%、96.71%、91.42%、94.01%和94.81%。此外,我们将我们提出的方法与最先进的算法的性能进行了比较。我们将我们的最佳HR-HRV健康参数模型与六种不同的最先进的PPG信号质量评估方法进行比较。结果表明,该方法的性能优于其他方法。我们还提供了用Python实现的开源模型,以便社区将其集成到他们的解决方案中。
{"title":"A Deep Learning-based PPG Quality Assessment Approach for Heart Rate and Heart Rate Variability","authors":"Emad Kasaeyan Naeini, Fatemeh Sarhaddi, I. Azimi, P. Liljeberg, N. Dutt, A. Rahmani","doi":"10.1145/3616019","DOIUrl":"https://doi.org/10.1145/3616019","url":null,"abstract":"Photoplethysmography (PPG) is a non-invasive optical method to acquire various vital signs, including heart rate (HR) and heart rate variability (HRV). The PPG method is highly susceptible to motion artifacts and environmental noise. Unfortunately, such artifacts are inevitable in ubiquitous health monitoring, as the users are involved in various activities in their daily routines. Such low-quality PPG signals negatively impact the accuracy of the extracted health parameters, leading to inaccurate decision-making. PPG-based health monitoring necessitates a quality assessment approach to determine the signal quality according to the accuracy of the health parameters. Different studies have thus far introduced PPG signal quality assessment methods, exploiting various indicators and machine learning algorithms. These methods differentiate reliable and unreliable signals, considering morphological features of the PPG signal and focusing on the cardiac cycles. Therefore, they can be utilized for HR detection applications. However, they do not apply to HRV, as only having an acceptable shape is insufficient, and other signal factors may also affect the accuracy. In this paper, we propose a deep learning-based PPG quality assessment method for HR and various HRV parameters. We employ one customized one-dimensional (1D) and three two-dimensional (2D) Convolutional Neural Networks (CNN) to train models for each parameter. Reliability of each of these parameters will be evaluated against the corresponding electrocardiogram signal, using 210 hours of data collected from a home-based health monitoring application. Our results show that the proposed 1D CNN method outperforms the other 2D CNN approaches. Our 1D CNN model obtains the accuracy of 95.63%, 96.71%, 91.42%, 94.01%, and 94.81% for the HR, average of normal to normal interbeat (NN) intervals (AVNN), root mean square of successive NN interval differences (RMSSD), standard deviation of NN intervals (SDNN), and ratio of absolute power in low frequency to absolute power in high frequency (LF/HF) ratios, respectively. Moreover, we compare the performance of our proposed method with state-of-the-art algorithms. We compare our best models for HR-HRV health parameters with six different state-of-the-art PPG signal quality assessment methods. Our results indicate that the proposed method performs better than the other methods. We also provide the open-source model implemented in Python for the community to be integrated into their solutions.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43819768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fundus Imaging-Based Healthcare: Present and Future 眼底成像医疗:现在与未来
Pub Date : 2023-07-31 DOI: 10.1145/3586580
Vijay Kumar, Kolin Paul
A fundus image is a two-dimensional pictorial representation of the membrane at the rear of the eye that consists of blood vessels, the optical disc, optical cup, macula, and fovea. Ophthalmologists use it during eye examinations to screen, diagnose, and monitor the progress of retinal diseases or conditions such as diabetes, age-marked degeneration (AMD), glaucoma, retinopathy of prematurity (ROP), and many more ocular ailments. Developments in ocular optical systems, image acquisition, processing, and management techniques over the past few years have contributed to the use of fundus images to monitor eye conditions and other related health complications. This review summarizes the various state-of-the-art technologies related to the fundus imaging device, analysis techniques, and their potential applications for ocular diseases such as diabetic retinopathy, glaucoma, AMD, cataracts, and ROP. We also present potential opportunities for fundus imaging–based affordable, noninvasive devices for scanning, monitoring, and predicting ocular health conditions and providing other physiological information, for example, heart rate (HR), blood components, pulse rate, heart rate variability (HRV), retinal blood perfusion, and more. In addition, we present different types of technological, economical, and sociological factors that impact the growth of the fundus imaging–based technologies for health monitoring.
眼底图像是眼底膜的二维图像,由血管、光盘、光学杯、黄斑和中央凹组成。眼科医生在眼科检查中使用它来筛查、诊断和监测视网膜疾病或诸如糖尿病、年龄标记变性(AMD)、青光眼、早产儿视网膜病变(ROP)和许多其他眼部疾病的进展。在过去几年中,眼部光学系统、图像采集、处理和管理技术的发展促进了眼底图像的使用,以监测眼部状况和其他相关的健康并发症。本文综述了与眼底成像设备、分析技术相关的各种最新技术及其在糖尿病视网膜病变、青光眼、AMD、白内障和ROP等眼病中的潜在应用。我们还提出了基于眼底成像的廉价无创设备的潜在机会,用于扫描、监测和预测眼部健康状况,并提供其他生理信息,例如心率(HR)、血液成分、脉搏率、心率变异性(HRV)、视网膜血液灌注等。此外,我们提出了影响眼底成像健康监测技术发展的不同类型的技术、经济和社会学因素。
{"title":"Fundus Imaging-Based Healthcare: Present and Future","authors":"Vijay Kumar, Kolin Paul","doi":"10.1145/3586580","DOIUrl":"https://doi.org/10.1145/3586580","url":null,"abstract":"A fundus image is a two-dimensional pictorial representation of the membrane at the rear of the eye that consists of blood vessels, the optical disc, optical cup, macula, and fovea. Ophthalmologists use it during eye examinations to screen, diagnose, and monitor the progress of retinal diseases or conditions such as diabetes, age-marked degeneration (AMD), glaucoma, retinopathy of prematurity (ROP), and many more ocular ailments. Developments in ocular optical systems, image acquisition, processing, and management techniques over the past few years have contributed to the use of fundus images to monitor eye conditions and other related health complications. This review summarizes the various state-of-the-art technologies related to the fundus imaging device, analysis techniques, and their potential applications for ocular diseases such as diabetic retinopathy, glaucoma, AMD, cataracts, and ROP. We also present potential opportunities for fundus imaging–based affordable, noninvasive devices for scanning, monitoring, and predicting ocular health conditions and providing other physiological information, for example, heart rate (HR), blood components, pulse rate, heart rate variability (HRV), retinal blood perfusion, and more. In addition, we present different types of technological, economical, and sociological factors that impact the growth of the fundus imaging–based technologies for health monitoring.","PeriodicalId":72043,"journal":{"name":"ACM transactions on computing for healthcare","volume":"4 1","pages":"1 - 34"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41913086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
ACM transactions on computing for healthcare
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1