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Advanced research in gastroenterology & hepatology最新文献

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Flavones as Potential Adjuvants for Therapeutic Treatments of Hepatocellular Carcinoma 黄酮作为肝细胞癌治疗的潜在佐剂
Pub Date : 2020-06-01 DOI: 10.19080/argh.2020.15.555907
Raymond P. Wu
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引用次数: 0
Brush Cytology- Alternative to Endoscopic Biopsy in Diagnosing Malignancy 刷细胞学-替代内镜活检诊断恶性肿瘤
Pub Date : 2020-05-09 DOI: 10.19080/argh.2020.15.555915
P. Malhotra, Ritesh Kumar, S. Chhabra, V. Malhotra, Y. Sanwariya, I. Pahuja
Journal of clinical gastroenterology is part of the Juniper publishers which is devoted to publish subject-specific articles focused on the needs of individual research communities across all areas of biology and medicine. Upper gastrointestinal tract lesions are the leading cause of morbidity and mortality worldwide. Upper gastrointestinal symptoms include dysphagia, vomiting, anorexia, retrosternal pain, weight loss and mass abdomen and patients may present with visible red and white mucosal lesions, ulcers, polypoidal or ulcerative growth in upper gastrointestinal tract (GIT)
《临床胃肠病学杂志》是Juniper出版社的一部分,该出版社致力于发表特定主题的文章,重点关注生物学和医学各个领域的个人研究社区的需求。上消化道病变是全球发病率和死亡率的主要原因。上消化道症状包括吞咽困难、呕吐、厌食、胸骨后疼痛、体重减轻和腹部肿块,患者可能出现可见的红白粘膜病变、溃疡、上消化道息肉状或溃疡性生长(GIT)
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引用次数: 0
Multiple Gastrointestinal Stromal Tumors of the Duodenum Associated with Neurofibromatosis Type 多发性十二指肠胃肠道间质瘤伴神经纤维瘤病
Pub Date : 2020-01-07 DOI: 10.19080/argh.2020.14.555889
S. Matsui
A 69-year-old woman patient, with known neurofibromatosis type 1(NF1), was admitted to our hospital for melena. Gastrointestinal endoscopy revealed several submucosal tumors with ulcer in the second of the duodenum. The patient underwent subtotal stomachpreserving pancreaticoduodenectomy (SSPPD). Those tumors were diagnosed gastrointestinal stromal tumors (GISTs) in the duodenum with NF1-related.
一名69岁的女性患者,患有已知的1型神经纤维瘤病(NF1),因黑便入院。胃肠内窥镜检查显示十二指肠第二节有多个黏膜下肿瘤伴溃疡。患者接受了保胃胰十二指肠大部切除术(SSPPD)。这些肿瘤被诊断为与NF1相关的十二指肠胃肠道间质瘤(GISTs)。
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引用次数: 0
Challenges and Prospects in the Provision of Counseling Services for Art Patients: The Case of Nekemte Referral Hospital, East Wollega, Oromia 为艺术患者提供咨询服务的挑战和前景:以奥罗米亚州东沃勒加内格蒙特转诊医院为例
Pub Date : 2019-11-13 DOI: 10.19080/argh.2019.14.555881
Abdissa Gemechu Gobena
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引用次数: 0
Helicobacter Pylori Infections, Gastrointestinal Diseases, Diagnostic Implications and Treatment Protocols: Recent Developments 幽门螺杆菌感染,胃肠道疾病,诊断意义和治疗方案:最新进展
Pub Date : 2019-11-12 DOI: 10.19080/argh.2019.14.555880
A. S. Giasuddin
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引用次数: 1
Proximal Esophageal Granular Cell Tumor: A Case Report and Review of Literature 食管近端颗粒细胞瘤1例报告及文献复习
Pub Date : 2019-09-25 DOI: 10.19080/argh.2019.13.555875
Hallal Mahmoud
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引用次数: 0
Opposing Roles of BMP and TGF-β Signaling Pathways in Pancreatitis: Mechanisms and Therapeutic Implication BMP和TGF-β信号通路在胰腺炎中的对立作用:机制和治疗意义
Pub Date : 2019-09-04 DOI: 10.19080/argh.2019.13.555871
Yanna Cao, M. Drake, Joy M. Davis, Baibing Yang, T. Ko
Bone morphogenetic proteins (BMPs) comprise a major subgroup of the transforming growth factor (TGF)-β superfamily. They play pivotal roles in embryonic development and tissue homeostasis in adults. Deregulation of BMP and TGF-β signaling contributes to developmental anomalies and multiple diseases. In this mini-review, we focus on BMP signaling in inflammatory disorders of the pancreas, acute and chronic pancreatitis, in contrast to TGF-β signaling. We then discuss molecular mechanisms that interact with and connect between the BMP and TGF-β signaling pathways. Lastly, we review potential implications of these molecular mechanisms for therapeutic development. In summary, BMP signaling pathway plays different roles during pancreatitis disease development, and the antagonism between BMP and TGF-β signaling can be manipulated for therapeutic development against pancreatitis.
骨形态发生蛋白(BMP)是转化生长因子(TGF)-β超家族的一个主要亚群。它们在成人胚胎发育和组织稳态中发挥着关键作用。BMP和TGF-β信号传导的失调导致发育异常和多种疾病。在这篇小型综述中,我们重点关注胰腺炎症性疾病、急性和慢性胰腺炎中的BMP信号传导,而不是TGF-β信号传导。然后,我们讨论了与BMP和TGF-β信号通路相互作用和连接的分子机制。最后,我们回顾了这些分子机制对治疗发展的潜在影响。总之,BMP信号通路在胰腺炎疾病的发展过程中发挥着不同的作用,BMP和TGF-β信号之间的拮抗作用可以用于胰腺炎的治疗发展。
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引用次数: 4
Drug Development Challenges in Hepatitis Clinical Trials 肝炎临床试验中的药物开发挑战
Pub Date : 2019-08-13 DOI: 10.19080/argh.2019.13.555869
M. Mouelhi
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引用次数: 0
Ensuring Adequate Iron Status in Vegetarians and Vegans 确保素食者和素食者体内充足的铁元素
Pub Date : 2019-07-26 DOI: 10.19080/argh.2019.13.555867
Stewart D Rose
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引用次数: 1
Antidiabetic and Hypolipidemic Effects of Methanol Leaf Extract of Newbouldia laevis in Alloxan Induced Diabetic Rats 牛蒡甲醇叶提取物对四氧嘧啶糖尿病大鼠的抗糖尿病和降脂作用
Pub Date : 2019-07-09 DOI: 10.19080/argh.2019.13.555863
Bosha Ja
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引用次数: 3
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Advanced research in gastroenterology & hepatology
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