Pub Date : 2019-03-11DOI: 10.19080/argh.2019.12.555843
N. Duchateau
{"title":"Malignant Degeneration of a Giant Hepatic Adenoma during Pregnancy","authors":"N. Duchateau","doi":"10.19080/argh.2019.12.555843","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555843","url":null,"abstract":"","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47202890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-07DOI: 10.19080/argh.2019.12.555841
P. Malhotra
{"title":"Successful Colonoscopic Removal of Missed Copper-T","authors":"P. Malhotra","doi":"10.19080/argh.2019.12.555841","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555841","url":null,"abstract":"","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47733469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-05DOI: 10.19080/argh.2019.12.555840
Elhasafi Am
{"title":"Study of Malignant Portal Vein Thrombosis in Hepatocellular Carcinoma and its Relation with Other Prognostic Factors","authors":"Elhasafi Am","doi":"10.19080/argh.2019.12.555840","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555840","url":null,"abstract":"","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47950827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-13DOI: 10.19080/argh.2019.12.555837
Stewart D Rose
Crohn’s disease is notoriously difficult to treat and this patient was no exception. Patients are typically treated with a wide range of drugs, most of which have significant side effects, and surgery. This is a case study of a 63-yr old male, who was first diagnosed with Crohn’s disease in 1988. Over the past thirty years, he experienced persistent pain, chronic diarrhea and chronic fatigue. Extraintestinal manifestations included aphthous stomatitis, arthralgia especially in the knees and hips, eczema and uveitis. His comorbidities included shingles, exacerbated by immunosuppression, severe post herpetic neuralgia, and noise-induced hearing loss of both ears. The patient also has benign prostatic hypertrophy and diverticulosis. Despite the full range of treatment, the patient remained with very significant symptoms, medication side effects and poor quality of life. In May 2017, the patient chose to go on a plant-based diet. Within two months, significant improvements in symptoms resulted. After three months, the patient was able to discontinue all immunosuppressant drugs. After one year, the patient reports no symptoms requiring medications other than ranitidine 150mg 2x/day and loperamide 10mg/day needed for post op management of resections. Fatigue, pain, diarrhea and all extraintestinal manifestations have virtually been eliminated. The patient reports a very large improvement in quality of life.
{"title":"Treating Crohn’s Disease with a Plant-Based Diet – a Case Report","authors":"Stewart D Rose","doi":"10.19080/argh.2019.12.555837","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555837","url":null,"abstract":"Crohn’s disease is notoriously difficult to treat and this patient was no exception. Patients are typically treated with a wide range of drugs, most of which have significant side effects, and surgery. This is a case study of a 63-yr old male, who was first diagnosed with Crohn’s disease in 1988. Over the past thirty years, he experienced persistent pain, chronic diarrhea and chronic fatigue. Extraintestinal manifestations included aphthous stomatitis, arthralgia especially in the knees and hips, eczema and uveitis. His comorbidities included shingles, exacerbated by immunosuppression, severe post herpetic neuralgia, and noise-induced hearing loss of both ears. The patient also has benign prostatic hypertrophy and diverticulosis. Despite the full range of treatment, the patient remained with very significant symptoms, medication side effects and poor quality of life. In May 2017, the patient chose to go on a plant-based diet. Within two months, significant improvements in symptoms resulted. After three months, the patient was able to discontinue all immunosuppressant drugs. After one year, the patient reports no symptoms requiring medications other than ranitidine 150mg 2x/day and loperamide 10mg/day needed for post op management of resections. Fatigue, pain, diarrhea and all extraintestinal manifestations have virtually been eliminated. The patient reports a very large improvement in quality of life.","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47043890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-13DOI: 10.19080/argh.2019.12.555839
B. Sander
Introduction: Obesity is a global disease and its management includes pharmacological therapy, non-absorptive surgery and intragastric balloon (IGB). The IGB has been used for more than 20 years in Brazil as an endoscopic method to aid in weight loss. Thus, the objective of this work was to describe the results of this procedure in IGB in Brazil. Methods: This prospective study had a total of 10,255 patients submitted to IGB between 1997 and 2017. Patients with IGB filled with a fluid volume of between 620 and 700 ml, and a minimum initial BMI of 27 kg/m2 were inserted non-study. The maximum follow-up time was nine months. Results: This is a specific motion (31.1 years), mostly women (78%). The mean BMI weight was: 33.42 ± 6.62 kg/m2, mean final BMI: 27.16 ± 8.42 kg/m2, p <0.01. The incidence of complications with IGB was 0.03% (n=3): gastric perforation. A total of 5.2% of the patients followed up for 18 months after a withdrawal of the IGB was submitted to bariatric surgery. Conclusion: IGB is a safe and effective technique for weight loss, with complication rates. With the assistance of a multidisciplinary team, the results were satisfactory.
肥胖症是一种全球性疾病，其治疗包括药物治疗、非吸收性手术和胃内球囊(IGB)。在巴西，IGB作为一种帮助减肥的内窥镜方法已经使用了20多年。因此，这项工作的目的是描述该程序在巴西IGB中的结果。方法:这项前瞻性研究共纳入了1997年至2017年间接受IGB治疗的10255例患者。IGB患者充液量在620至700毫升之间，初始BMI最低为27 kg/m2，被插入非研究。最长随访时间为9个月。结果:这是一个特定的运动(31.1岁)，主要是女性(78%)。平均BMI体重为:33.42±6.62 kg/m2，平均终末BMI为:27.16±8.42 kg/m2, p <0.01。IGB并发症发生率为0.03% (n=3):胃穿孔。停用IGB后随访18个月的患者中，有5.2%接受了减肥手术。结论:IGB是一种安全有效的减肥技术，并发症发生率低。在多学科小组的协助下，结果令人满意。
{"title":"Intragastric Balloon: A Large Brazilian Multicentric Study Over 10,000 Cases and 20 Years of Experience","authors":"B. Sander","doi":"10.19080/argh.2019.12.555839","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555839","url":null,"abstract":"Introduction: Obesity is a global disease and its management includes pharmacological therapy, non-absorptive surgery and intragastric balloon (IGB). The IGB has been used for more than 20 years in Brazil as an endoscopic method to aid in weight loss. Thus, the objective of this work was to describe the results of this procedure in IGB in Brazil. Methods: This prospective study had a total of 10,255 patients submitted to IGB between 1997 and 2017. Patients with IGB filled with a fluid volume of between 620 and 700 ml, and a minimum initial BMI of 27 kg/m2 were inserted non-study. The maximum follow-up time was nine months. Results: This is a specific motion (31.1 years), mostly women (78%). The mean BMI weight was: 33.42 ± 6.62 kg/m2, mean final BMI: 27.16 ± 8.42 kg/m2, p <0.01. The incidence of complications with IGB was 0.03% (n=3): gastric perforation. A total of 5.2% of the patients followed up for 18 months after a withdrawal of the IGB was submitted to bariatric surgery. Conclusion: IGB is a safe and effective technique for weight loss, with complication rates. With the assistance of a multidisciplinary team, the results were satisfactory.","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48889604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-13DOI: 10.19080/argh.2019.12.555838
G. Rubí
{"title":"Prevalence of HCV in Pakistani Population","authors":"G. Rubí","doi":"10.19080/argh.2019.12.555838","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555838","url":null,"abstract":"","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47766837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-04DOI: 10.19080/argh.2019.12.555833
P. Malhotra
Introduction: Viral hepatitis is recognized as a public health problem in India and globally. Various etiological agents (Hepatitis A, B, C, D, E and G virus) have been implicated that can lead to acute, chronic or acute on chronic infection. While Hepatitis A and E are often the cause of sporadic outbreaks of hepatitis, Hepatitis B and C can either clear spontaneously or can lead to chronic infection and thereafter sequel like cirrhosis and hepatocellular carcinoma (HCC). Aims & objectives: To determine the genotyping of HCV infections among chronic hepatitis patients attending Department of Gastroenterology, PGIMS Rohtak. Summary and conclusions Our study confirms the finding of previous studies that in India Genotype 3 is most common genotype which is difficult to treat Genotype with oral antiviral therapy. Hence as per World Health Organization target of elimination of Hepatitis C till 2030 requires continuous, persistent and determined efforts at level of Center, State and society level.
{"title":"Genotypic Distribution of Hcv in Northeren India","authors":"P. Malhotra","doi":"10.19080/argh.2019.12.555833","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555833","url":null,"abstract":"Introduction: Viral hepatitis is recognized as a public health problem in India and globally. Various etiological agents (Hepatitis A, B, C, D, E and G virus) have been implicated that can lead to acute, chronic or acute on chronic infection. While Hepatitis A and E are often the cause of sporadic outbreaks of hepatitis, Hepatitis B and C can either clear spontaneously or can lead to chronic infection and thereafter sequel like cirrhosis and hepatocellular carcinoma (HCC). Aims & objectives: To determine the genotyping of HCV infections among chronic hepatitis patients attending Department of Gastroenterology, PGIMS Rohtak. Summary and conclusions Our study confirms the finding of previous studies that in India Genotype 3 is most common genotype which is difficult to treat Genotype with oral antiviral therapy. Hence as per World Health Organization target of elimination of Hepatitis C till 2030 requires continuous, persistent and determined efforts at level of Center, State and society level.","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46814756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-04DOI: 10.19080/argh.2019.12.555836
D. Dia
{"title":"Clinical, Paraclinical and Etiological Aspects of Cirrhosis in a Department of Internal Medicine in Senegal","authors":"D. Dia","doi":"10.19080/argh.2019.12.555836","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555836","url":null,"abstract":"","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43880246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-04DOI: 10.19080/argh.2019.12.555835
R. Guy
The RET proto-oncogene is located on chromosome 10q11.2 and encodes a transmembrane receptor tyrosine kinase that has three unique isoforms [1]. Four ligands can bind and activate RET, leading to the aberrant activity of several signaling pathways including PI3K/Akt and MAPK pathway [2]. The aberrant expression of RET may function as an oncogene in certain solid tumor malignancies including papillary, medullary thyroid cancers and the multiple endocrine neoplasm type 2 (MEN2) syndrome [3,4].
{"title":"Association between Germline Mutations in the RET Proto-Oncogene and Colorectal Cancer and Polyps","authors":"R. Guy","doi":"10.19080/argh.2019.12.555835","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555835","url":null,"abstract":"The RET proto-oncogene is located on chromosome 10q11.2 and encodes a transmembrane receptor tyrosine kinase that has three unique isoforms [1]. Four ligands can bind and activate RET, leading to the aberrant activity of several signaling pathways including PI3K/Akt and MAPK pathway [2]. The aberrant expression of RET may function as an oncogene in certain solid tumor malignancies including papillary, medullary thyroid cancers and the multiple endocrine neoplasm type 2 (MEN2) syndrome [3,4].","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48318897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-25DOI: 10.19080/argh.2019.12.555832
M. El-Loly
The concept that milk, mammary secretions and the mammary gland have significant roles in immune defense is an old one. The bactericidal property of milk was recorded in the late nineteenth century. Also, observations at this time on the ability of milk to provide immunity to the newborn assumed a key role in the development of modern immunology. The mammalian neonate can’t to collect, chew, or digest solid food, depending completely on the colostrum of its mother and subsequently on milk for its survival. In addition to providing a complete diet with all the essential nutrients for the neonate through the initial period of its life, colostrum also gives basic immunological protection against surrounding pathogens. In ruminants specifically, for which no exchange of immune factors happens in uteri, colostrum and milk provide protection through high immunoglobulins (Igs) or antibodies content, without which the ruminant would not, survive Larson et al. [1].
{"title":"Immune Defenses of Colostrum and Milk in Human and Animals","authors":"M. El-Loly","doi":"10.19080/argh.2019.12.555832","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555832","url":null,"abstract":"The concept that milk, mammary secretions and the mammary gland have significant roles in immune defense is an old one. The bactericidal property of milk was recorded in the late nineteenth century. Also, observations at this time on the ability of milk to provide immunity to the newborn assumed a key role in the development of modern immunology. The mammalian neonate can’t to collect, chew, or digest solid food, depending completely on the colostrum of its mother and subsequently on milk for its survival. In addition to providing a complete diet with all the essential nutrients for the neonate through the initial period of its life, colostrum also gives basic immunological protection against surrounding pathogens. In ruminants specifically, for which no exchange of immune factors happens in uteri, colostrum and milk provide protection through high immunoglobulins (Igs) or antibodies content, without which the ruminant would not, survive Larson et al. [1].","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43203405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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