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Advanced research in gastroenterology & hepatology最新文献

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The Influence of Menopause on Inflammatory Cytokine and Adipocytokines Profile in Saudi Women 更年期对沙特妇女炎症细胞因子和脂肪细胞因子谱的影响
Pub Date : 2019-05-10 DOI: 10.19080/argh.2019.13.555851
M. S. Al-dahr
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引用次数: 0
Ensuring Adequate Vitamin B12 Status on a Plant-Based Diet 确保植物性饮食中有足够的维生素B12
Pub Date : 2019-05-10 DOI: 10.19080/argh.2019.13.555862
Stewart D Rose
Vitamin B12 is a water-soluble vitamin that is naturally present in animal-derived foods. It is added to others and is available as a dietary supplement and a prescription medication. Vitamin B12 exists in several forms and contains the mineral cobalt [1-4], so compounds with vitamin B12 activity are collectively called “cobalamins”. Methylcobalamin and 5-deoxyadenosylcobalamin are the forms of vitamin B12 that are active in human metabolism [5].
维生素B12是一种水溶性维生素,天然存在于动物性食物中。它被添加到其他人身上,可以作为膳食补充剂和处方药使用。维生素B12以多种形式存在,并含有矿物质钴[1-4],因此具有维生素B12活性的化合物统称为“钴胺素”。甲基钴胺素和5-脱氧腺苷钴胺素是维生素B12的形式,在人体代谢中很活跃。
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引用次数: 0
Antibiotic-Resistant Bacteria in Hospital Sewages and Treated Urban Wastewater: A Case Study from Marrakech (Morocco) 马拉喀什(摩洛哥)医院污水和城市污水中的抗生素耐药性细菌研究
Pub Date : 2019-05-10 DOI: 10.19080/argh.2019.12.555850
L. Mandi
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引用次数: 1
Sleeve Gastric Resection for Morbid Obesity: It’s the Time to Revise the Surgical Technique? 袖珍胃切除术治疗病态肥胖:是时候修改手术技术了?
Pub Date : 2019-04-29 DOI: 10.19080/argh.2019.12.555849
M. Marchese
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引用次数: 0
Associations between Body Composition, Disease Activity and Quality of Life in Patients with Crohn’s Disease: A Cross-Sectional Study 克罗恩病患者身体组成、疾病活动度和生活质量之间的关系:一项横断面研究
Pub Date : 2019-04-22 DOI: 10.19080/argh.2019.12.555848
M. Hilligsøe, Niklas D Eriksen, Marian Jacobsen, L. H. Kaagaard, H. Rasmussen, L. Vinter‐Jensen, M. Holst
Background & Aims: Patients with Crohn’s disease (CD) treated with tumor necrosis factor-α (TNF-α) inhibitors are heterogeneous and respond differently to treatment. We aimed to investigate if disease activity and quality of life were associated with the individual varying distribution of fat and fat free mass. Methods: A sample of 83 CD patients treated with TNF-α inhibitors were examined in this single center, cross-sectional study. Body composition was measured by bioelectrical impedance analysis (BIA) and muscle function by handgrip strength (HGS). The association to disease activity assessed by Harvey-Bradshaw Index (HBI), Creactive protein (CRP) and quality of life assessed by Short Health Scale (SHS) was investigated. Results: Increased fat mass index (FMI) was significantly associated to higher disease activity assessed by HBI (p < 0.05) and showed a trend toward a higher CRP level in multivariate non-parametric regression analyses (p=0.07). Univariate tests showed a significant positive association between FMI and SHS as well. Fat free mass index (FFMI) and HGS were not associated to disease activity or quality of life in this population. Conclusion: Despite TNF-α inhibitor therapy, one third of the patients in this study experienced active disease. High FMI was significantly associated to increased disease activity and decreased quality of life. No associations were seen between FFMI, HGS and body composition. Larger studies are needed to confirm these results, and to investigate confounders.
背景与目的:使用肿瘤坏死因子-α (TNF-α)抑制剂治疗的克罗恩病(CD)患者具有异质性,对治疗的反应不同。我们的目的是调查疾病活动和生活质量是否与个体不同的脂肪和无脂肪量分布有关。方法:在这项单中心横断面研究中,对83例接受TNF-α抑制剂治疗的CD患者进行了检查。用生物电阻抗分析法(BIA)测定体成分,用握力分析法(HGS)测定肌肉功能。用Harvey-Bradshaw指数(HBI)、CRP (CRP)和SHS (Short Health Scale)评估生活质量与疾病活动性的关系。结果:脂肪质量指数(FMI)的增加与HBI评估的疾病活动性升高显著相关(p < 0.05),多变量非参数回归分析显示CRP水平升高的趋势(p=0.07)。单变量检验也显示FMI与SHS之间存在显著正相关。无脂肪质量指数(FFMI)和HGS与该人群的疾病活动或生活质量无关。结论:尽管TNF-α抑制剂治疗,本研究中仍有三分之一的患者出现活动性疾病。高FMI与疾病活动性增加和生活质量下降显著相关。FFMI、HGS和身体成分之间没有关联。需要更大规模的研究来证实这些结果,并调查混杂因素。
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引用次数: 0
Biliary Ascariasis 胆道蛔虫病
Pub Date : 2019-04-03 DOI: 10.19080/argh.2019.12.555847
S. Islam
One quarter of world’s population is known to be affected by ascariasis. It is endemic in various parts of the subcontinent. Gangetic plain of Bangladesh, West Bengal, Kashmere valley are examples. Biliary ascaiasis is one of the manifestations of ascariasis. We searched literature published from both endemic and non-endemic area and aimed to study different types of clinical presentation, diagnostic tool, complications and their frequency and various treatment option for the management of biliary ascariasis. Biliary colic is the commonest symptom. Acute cholecystitis, obstructive jaundice, cholangitis, pancreatitis, hepatolithiasis, liver abscess are other mode of presentation. Ultrasonography is an excellent non –invasive investigation for diagnosis and follow up of this condition. Majority of cases are treated conservatively. ERCP (Endoscopic Retrograde Cholangio Pancreatography) based extraction of Ascaris lubricoids is possible in most of the situation where expert endoscopy services are available. Open common bile duct exploration and removal of worm is necessary in absence of endoscopy. Improvement of personal hygiene, improvement of sanitation and regular anti-helminthic administration can reduce this dreadful consequence of infestation by worms.
已知世界上四分之一的人口受到蛔虫感染。它在次大陆的各个地区都很流行。孟加拉国恒河平原、西孟加拉邦、克什米尔山谷就是一个例子。胆道蛔虫症是蛔虫症的表现之一。我们检索了流行区和非流行区发表的文献,旨在研究不同类型的临床表现、诊断工具、并发症及其频率以及治疗胆道蛔虫症的各种治疗方案。胆绞痛是最常见的症状。急性胆囊炎、梗阻性黄疸、胆管炎、胰腺炎、肝结石、肝脓肿是其他表现形式。超声检查是诊断和随访这种情况的一种极好的非侵入性检查。大多数病例采用保守治疗。在大多数有专家内镜服务的情况下,基于ERCP(内镜逆行胆胰造影术)的蛔虫类提取是可能的。在没有内窥镜检查的情况下,有必要对胆总管进行开放性探查并去除蠕虫。改善个人卫生、改善环境卫生和定期服用驱虫药可以减少蠕虫感染的可怕后果。
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引用次数: 0
Antioxidant and Hepatoprotective Potential of Dragon Fruit Extract in Opposition to Acetaminophen-Induce Liver Smash Up in Rats 火龙果提取物抗对乙酰氨基酚致大鼠肝脏损伤的抗氧化和保肝作用
Pub Date : 2019-03-15 DOI: 10.19080/argh.2019.12.555846
M. Parmar
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引用次数: 3
Hepatitis B Treatment in Light of Natural Sources 从自然来源看乙型肝炎的治疗
Pub Date : 2019-03-13 DOI: 10.17352/AHR.000020
Aisha Shehzad, Abida Hussain, Shifa Iman, Sohail Ahmed Faiza Naseer
Background: The harm of liver cirrhosis (LC) is serious, and the development of LC is primarily resulted from chronic hepatitis B virus (HBV) in high-risk such as China and Africa and chronic hepatitis C virus (HCV) in developed areas such as United States.
背景:肝硬化(LC)危害严重,其发展主要是由中国和非洲等高危地区的慢性乙型肝炎病毒(HBV)和美国等发达地区的慢性丙型肝炎病毒(HCV)引起的。
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引用次数: 0
Therapeutic Potential of Lab-Grown Autologous BioSphincters for the Treatment of Fecal Incontinence in a Long-Term Pre-Clinical Study 长期临床前研究中实验室培育的自体生物括约肌治疗排便失禁的潜力
Pub Date : 2019-03-12 DOI: 10.19080/argh.2019.12.555845
E. Zakhem
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引用次数: 2
Peritoneal Shunt Catheter Migration into the Stomach: Case Report and Review of Literature 腹膜分流术导管移入胃的病例报告及文献复习
Pub Date : 2019-03-11 DOI: 10.19080/argh.2019.12.555844
Y. K. Reddy
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引用次数: 1
期刊
Advanced research in gastroenterology & hepatology
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