Advances in ophthalmology practice and research最新文献

{"title":"The effect of COVID-19 on visual outcome and dry eye after SMILE","authors":"Zhi Fang ,&nbsp;Yan Li ,&nbsp;Dejuan Song,&nbsp;Xiaoying He,&nbsp;Kai Zhang,&nbsp;Tiepei Zhu,&nbsp;Wei Han","doi":"10.1016/j.aopr.2025.01.001","DOIUrl":"10.1016/j.aopr.2025.01.001","url":null,"abstract":"<div><h3>Purposes</h3><div>To evaluate the impact of coronavirus disease 2019 (COVID-19) on postoperative visual acuity, optical quality, and severity of dry eye disease in patients after small incision lenticule extraction (SMILE).</div></div><div><h3>Methods</h3><div>This is a retrospective, comparative study. Patients who underwent SMILE were included and divided into two groups according to the period at the eye center of the Second Affiliated Hospital of Zhejiang University. The first group included patients who underwent SMILE before the large-scale COVID-19 pandemic in China (Group 1). The second group comprised patients who underwent SMILE during the pandemic with a confirmed infection of COVID-19 (Group 2). The visual acuity, the severity of dry eye, ocular surface disease index (OSDI), oculus keratography analysis, and individual Zernike coefficients were evaluated and compared between the 2 groups.</div></div><div><h3>Results</h3><div>A total of 43 eyes of 23 patients and 45 eyes of 26 patients were included in Groups 1 and 2, respectively. The OSDI score in Group 2 was significantly higher than Group 1 (<em>P</em> ​&lt; ​0.01). The corrected distance visual acuity (CDVA, logMAR) at 3 months postoperatively in Group 1 was better than in Group 2 (<em>P</em> ​&lt; ​0.001). Despite the improvement over 1 month after the COVID-19 infection, the OSDI score was still higher in Group 2 than in Group 1 (<em>P</em> ​&lt; ​0.01). The bulbar and limbal redness were significantly higher in Group 2 than in Group 1 ​at both 1 month and 3 months (<em>P</em> ​&lt; ​0.05), while no significant differences were found in tear breakup time or tear meniscus height. Spherical aberration (SA) at the 4 ​mm zone was significantly higher in Group 2 than in Group 1 both at 1 month and 3 months (<em>P</em> ​&lt; ​0.001), while no significant changes were observed in corneal total higher-order aberrations. No significant correlation was found between the bulbar/limbal redness index and SA.</div></div><div><h3>Conclusions</h3><div>COVID-19 infection impaired visual outcomes and aggravated dry eye severity among postoperative SMILE patients.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"5 2","pages":"Pages 149-155"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of popular large language models in glaucoma patient education: A randomized controlled study","authors":"Yuyu Cao ,&nbsp;Wei Lu ,&nbsp;Runhan Shi ,&nbsp;Fuying Liu ,&nbsp;Steven Liu ,&nbsp;Xinwei Xu ,&nbsp;Jin Yang ,&nbsp;Guangyu Rong ,&nbsp;Changchang Xin ,&nbsp;Xujiao Zhou ,&nbsp;Xinghuai Sun ,&nbsp;Jiaxu Hong","doi":"10.1016/j.aopr.2024.12.002","DOIUrl":"10.1016/j.aopr.2024.12.002","url":null,"abstract":"<div><h3>Purpose</h3><div>The advent of chatbots based on large language models (LLMs), such as ChatGPT, has significantly transformed knowledge acquisition. However, the application of LLMs in glaucoma patient education remains elusive. In this study, we comprehensively compared the performance of four common LLMs – Qwen, Baichuan 2, ChatGPT-4.0, and PaLM 2 – in the context of glaucoma patient education.</div></div><div><h3>Methods</h3><div>Initially, senior ophthalmologists were asked with scoring responses generated by the LLMs, which were answers to the most frequent glaucoma-related questions posed by patients. The Chinese Readability Platform was employed to assess the recommended reading age and reading difficulty score of the four LLMs. Subsequently, optimized models were filtered, and 29 glaucoma patients participated in posing questions to the chatbots and scoring the answers within a real-world clinical setting. Attending ophthalmologists were also required to score the answers across five dimensions: correctness, completeness, readability, helpfulness, and safety. Patients, on the other hand, scored the answers based on three dimensions: satisfaction, readability, and helpfulness.</div></div><div><h3>Results</h3><div>In the first stage, Baichuan 2 and ChatGPT-4.0 outperformed the other two models, though ChatGPT-4.0 had higher recommended reading age and reading difficulty scores. In the second stage, both Baichuan 2 and ChatGPT-4.0 demonstrated exceptional performance among patients and ophthalmologists, with no statistically significant differences observed.</div></div><div><h3>Conclusions</h3><div>Our research identifies Baichuan 2 and ChatGPT-4.0 as prominent LLMs, offering viable options for glaucoma education.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"5 2","pages":"Pages 88-94"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano-based drug delivery systems for the treatment of non-infectious uveitis","authors":"Xingdi Wu ,&nbsp;Mengyuan Hu ,&nbsp;Yilu Cai ,&nbsp;Fan Jia ,&nbsp;Yang Ye ,&nbsp;Naiji Yu ,&nbsp;Min Chen ,&nbsp;Kaijun Wang","doi":"10.1016/j.aopr.2024.11.003","DOIUrl":"10.1016/j.aopr.2024.11.003","url":null,"abstract":"<div><h3>Background</h3><div>Uveitis is one of the most prevalent causes of global visual impairment. The current approaches to treating non-infectious uveitis (NIU) involve the utilization of corticosteroids, immunosuppressant and biologics agents. Nevertheless, the intricate ocular anatomy barriers and adverse side effects of the drugs pose significant obstacles to effective treatment outcomes.</div></div><div><h3>Main text</h3><div>To improve drug bioavailability and therapeutic outcomes for NIU while minimize side effects, researchers are committed to developing novel nano-based drug delivery systems (DDS), which have the capacity to achieve targeted delivery, increase bioavailability, achieve sustained release, reduce side effects and improve therapeutic effects. Thus, DDS based on nanotechnology, including liposome, dendrimer, hydrogels, nanoparticles, nanomicelles, nanosuspensions and nanoemulsions have emerged as promising alternatives to conventional ocular delivery methods for the management of NIU.</div></div><div><h3>Conclusions</h3><div>In this review, we summarize the current therapeutic challenges faced by NIU and describe various nano-based intraocular DDS involved in the treatment of NIU. It is concluded that nano-based DDS is an appealing approach to addressing the unmet needs for the treatment of NIU.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"5 2","pages":"Pages 124-134"},"PeriodicalIF":0.0,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of refraction disorders in 204 countries and territories from 1990 to 2021: A systematic analysis from the global burden of disease 2021","authors":"Yunhan Shen ,&nbsp;Linyan Wang ,&nbsp;Yuxin Cui ,&nbsp;Bangxun Mao ,&nbsp;Grace Loy Ming Hooi ,&nbsp;Oluwatobi Idowu ,&nbsp;Juan Ye ,&nbsp;Tiansheng Zhu","doi":"10.1016/j.aopr.2024.11.001","DOIUrl":"10.1016/j.aopr.2024.11.001","url":null,"abstract":"<div><h3>Background</h3><div>Refraction disorders are common eye conditions that cause blurred vision and, if left uncorrected, remain a leading cause of moderate to severe visual impairment worldwide. Despite this, a comprehensive assessment of the associated burden is lacking. This study aims to describe and predict the burden and regional distribution of refraction disorders using data from the 2021 Global Burden of Disease (GBD) study.</div></div><div><h3>Methods</h3><div>This study utilized data from the Global Burden of Disease (GBD) 2021 on refraction disorders from 1990 to 2021. We analyzed the prevalence and disability-adjusted life years (DALYs) of refraction disorders and calculated the corresponding average annual percentage changes (AAPCs) in different gender and age groups across 204 countries and territories and 21 geographical regions. We employed the Bayesian Age-Period-Cohort (BAPC) model to predict the future burden of refraction disorders.</div></div><div><h3>Results</h3><div>From 1990 to 2021, the global age-standardized prevalence rate (ASPR) of refraction disorders decreased from 2053.56 (per 100000, 95% Uncertainty Interval [UI]: 1835.31 to 2275.80) to 1919.66 (per 100000, 95%UI: 1715.24 to 2135.28), with an average annual percentage change (AAPC) of −0.21% (95% Confidence Interval [CI]: −0.23% to −0.19%). The age-standardized DALY (Disability-Adjusted Life Years) rate also declined from 88.04 (per 100000, 95%UI: 62.19 to 125.15) to 79.11 (per 100000, 95%UI: 54.94 to 114.14) with an AAPC of −0.33% (95%CI: −0.36% to −0.31%). Refraction disorders remain a significant burden in regions with lower Socio-demographic Index (SDI), particularly in parts of South Asia and Western Sub-Saharan Africa. Older individuals and females are disproportionately affected. The age-standardized DALY rate is expected to decline steadily before stabilising at approximately 77.94 per 100000 by 2030.</div></div><div><h3>Conclusions</h3><div>From 1990 to 2021, the disease burden of refraction disorders showed a declining trend, but the decrease was not substantial. In some low-middle SDI regions, the burden remains high. Moreover, globally, women bear a higher burden than men. This study provides important information for the treatment and prevention of refraction disorders.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"5 2","pages":"Pages 79-87"},"PeriodicalIF":0.0,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TOC","authors":"","doi":"10.1016/S2667-3762(24)00066-0","DOIUrl":"10.1016/S2667-3762(24)00066-0","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 4","pages":"Pages iii-iv"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global incidence and prevalence in uveal melanoma","authors":"Xincen Hou ,&nbsp;Alexander C. Rokohl ,&nbsp;Xueting Li ,&nbsp;Yongwei Guo ,&nbsp;Xiaojun Ju ,&nbsp;Wanlin Fan ,&nbsp;Ludwig M. Heindl","doi":"10.1016/j.aopr.2024.10.001","DOIUrl":"10.1016/j.aopr.2024.10.001","url":null,"abstract":"<div><h3>Purpose</h3><div>The most common intraocular cancer in adults is uveal melanoma (UM). This study aimed to investigate and report the incidence and prognosis of UM in different regions of the world.</div></div><div><h3>Methods</h3><div>We retrieved relevant data on UM from the PubMed database and analyzed its global incidence and prognosis. All data was obtained from a national population-based registry, with publication dates ranging from 2013 to 2023.</div></div><div><h3>Results</h3><div>The incidence rates of UM vary across different regions: in the United States, rates were 5.1 per million (1993–2008) and 5.2 per million (1973–2013); in Canada, rates ranged from 3.34 per million (1992–2010) to 5.09 per million (2011–2017); in Republic of Korea, the rate was 0.42 per million (1999–2011); in New Zealand, it was 5.56 per million (2000–2020); in Australia, it was 7.6 per million (1982–2014); and in Europe, rates ranged from 3.1 to 5.8 per million (1995–2002). Among European countries, Sweden (5.6 per million (1960–2009)), Germany (6.41 per million (2009–2015)), Poland (6.67 per million (2010–2017)), and the United Kingdom (10 per million (1999–2010)).</div></div><div><h3>Conclusions</h3><div>The most common site of occurrence for UM is in the choroid. Limited data suggest a stable trend in UM incidence rates across the included countries, but significant differences in incidence rates exist among different countries and regions, with notably lower rates in Asian countries compared to Europe, North America, and Oceania. In general, the incidence rate in males is slightly higher compared to that in females.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 4","pages":"Pages 226-232"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142662751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcome of sequential bilateral pediatric penetrating keratoplasty (PKP) in patients with corneal dystrophies in South India","authors":"Rekha Gyanchand,&nbsp;B. Mamatha,&nbsp;Salma Mohd Iqbal Tabani,&nbsp;Rajan Sharma,&nbsp;Ashok Sharma","doi":"10.1016/j.aopr.2024.09.003","DOIUrl":"10.1016/j.aopr.2024.09.003","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 4","pages":"Pages 216-219"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An updated systematic review of pharmacological treatments for presbyopia","authors":"Andrzej Grzybowski ,&nbsp;Laura Kapitanovaite ,&nbsp;Reda Zemaitiene","doi":"10.1016/j.aopr.2024.09.001","DOIUrl":"10.1016/j.aopr.2024.09.001","url":null,"abstract":"<div><h3>Background</h3><div>Presbyopia, a common age-related condition affecting near vision, impacts over a billion people worldwide. The aim of this paper is to review the main reports and results of clinical trials, comparing the newest pharmacological treatment options for presbyopia, their mechanisms of action, and possible side effects.</div></div><div><h3>Main text</h3><div>Pharmacological approaches, involving eye drops that target the underlying mechanisms of presbyopia, have gained growing interest. Two key pharmacological agents in this field are miotics and lens softeners. Miotics enhance near vision temporarily by creating a pinhole effect, though they may cause side effects and are under further investigation for long-term use with ongoing research also exploring the potential benefits of combining them with other drugs to improve outcomes and reduce adverse reactions. Lens softeners, on the other hand, aim to restore the flexibility of the lens, addressing one of the primary causes of presbyopia. Despite early trials, further development of lens softeners has been suspended. A notable advancement in this field is the recent FDA approval of 1.25% and 0.4% pilocarpine, a miotic agent, for presbyopia treatment. This milestone highlights the growing interest in pharmacological solutions for presbyopia, with several new drugs and their combinations currently being investigated for potential FDA approval.</div></div><div><h3>Conclusions</h3><div>pharmacological treatments, particularly miotics like pilocarpine, represent a promising alternative to conventional methods for managing presbyopia. Continued research into these treatments, especially combinations of drugs, may offer more effective and convenient options for presbyopia patients in the future.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 4","pages":"Pages 220-225"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global research trends in the treatment of squamous cell carcinoma over the past decade: A bibliometric analysis","authors":"Xueting Li ,&nbsp;Alexander C. Rokohl ,&nbsp;Xiaojun Ju ,&nbsp;Yongwei Guo ,&nbsp;Xincen Hou ,&nbsp;Wanlin Fan ,&nbsp;Ludwig M. Heindl","doi":"10.1016/j.aopr.2024.08.001","DOIUrl":"10.1016/j.aopr.2024.08.001","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to identify research trends and hot spots in the treatment of Squamous Cell Carcinoma (SCC) over the past decade using bibliometric analysis.</div></div><div><h3>Methods</h3><div>Data were extracted from the Web of Science Core Collection, including Science Citation Index Expanded (SCI-Expanded), Social Sciences Citation Index (SSCI), and Emerging Sources Citation Index (ESCI). The data underwent manual cleaning to remove inaccuracies and irrelevancies, followed by transformation into an analyzable format via the VOSviewer software. This tool facilitated the visualization of co-occurrence networks and keyword maps, highlighting the relationships and the prominence of research themes.</div></div><div><h3>Results</h3><div>A total of 46448 authors from 7374 institutions across 108 countries contributed to the literature, reflecting a broad international effort. The study documented a consistent increase in SCC-related publications up to 2020, with some variability in subsequent years. Notably, the United States, Germany, China, the United Kingdom, and France were predominant in this research area. The University of Texas MD Anderson Cancer Center and the University of Pittsburgh were leading contributors in terms of publication volume and citation impact. Key journals included ‘Oral Oncology’ and ‘Clinical Cancer Research’, which were central to the dissemination of high-impact research. Our keyword analysis identified three major research clusters focused on molecular mechanisms, clinical treatment strategies, and emerging interests in immunotherapeutic approaches.</div></div><div><h3>Conclusions</h3><div>The extensive collaboration and the increasing publication trend underscore the growing global commitment to advancing SCC treatment. The high level of engagement from top institutions and the concentration of research in influential journals reflect the field's dynamic evolution towards innovative and effective treatment modalities. This study provides a valuable overview for researchers, guiding future studies towards areas of high impact and emerging trends in SCC treatment. The findings advocate for enhanced focus on personalized medicine and combination therapies, which are poised to improve outcomes for SCC patients.</div></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 4","pages":"Pages 209-215"},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142437836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding parental hurdles in accessing strabismus treatment","authors":"Omna Chawla ,&nbsp;Anupam Singh ,&nbsp;Himani Pal ,&nbsp;Sanjeev Kumar Mittal ,&nbsp;Srishti Sharma ,&nbsp;Mittali Khurana ,&nbsp;Pooja Kumari ,&nbsp;Barun Kumar","doi":"10.1016/j.aopr.2024.08.004","DOIUrl":"10.1016/j.aopr.2024.08.004","url":null,"abstract":"<div><h3>Purpose</h3><p>To explore the parental factors that impede early intervention for strabismus and thus identify strategies for improving access to specialized care.</p></div><div><h3>Methods</h3><p>This hospital-based cross-sectional study included 110 parents of children under 19 years with strabismus receiving treatment at the squint clinic of a tertiary health care center in north India. A pre-validated survey questionnaire was administered to the participants, that had a section about the socio-demographics of the participants, another section addressed the parental knowledge about strabismus about diagnosis, and the need for an eye examination. It also sought information about referral source, the felt need for squint examination, and reasons for not seeking treatment.</p></div><div><h3>Results</h3><p>A total of 110 parents/guardians of strabismus patients (59 exotropes and 51 esotropes) were interviewed using a survey questionnaire. Parents themselves identified 80% of cases, and a substantial link (<em>P</em> ​&lt; ​0.0001) was found between the education status of parents and the age of identification of strabismus. Fear of surgical outcomes (41.79%) was a significant barrier to timely surgery with a higher percentage of parents expressing fear of surgical outcomes (<em>P</em> ​= ​0.025). The cost of surgery (34.33%) and the non-availability of facilities (23.88%) also delayed the intervention.</p></div><div><h3>Conclusions</h3><p>It is essential to educate parents about the importance of strabismus therapy at an appropriate time, stressing its reconstructive rather than merely cosmetic nature, as there are notable gaps in their knowledge. Also, we need to do away with the fear of surgical outcomes of surgical interventions for strabismus.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":"4 4","pages":"Pages 189-193"},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376224000520/pdfft?md5=af61d93bbb8173147dd3fcf570581767&pid=1-s2.0-S2667376224000520-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142147983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}