Pub Date : 2022-05-01DOI: 10.1016/j.aopr.2022.100043
Kata Miháltz , Stephan Szegedi , Jolanda Steininger , Pia Veronika Vécsei-Marlovits
Purpose
To evaluate patient satisfaction after implantation of the Tecnis Symfony multifocal intraocular lens (MIOL).
Methods
120 eyes of 60 subjects with senile cataract were bilaterally implanted with the Tecnis Symfony IOL. Follow-up examination was performed 6 months postoperatively. Main outcome measures included uncorrected and corrected distance and near visual acuity, manifest refraction, and visual quality metrics. According to their subjective symptoms patient were divided in two groups: satisfied and unsatisfied.
Results
Uncorrected intermediate (0.15 ± 0.11 vs 0.18 ± 0.01, P = 0.04) and near (0.26 ± 0.12 vs 0.31 ± 0.11, P = 0.04) (UIVA, UNVA) log MAR visual acuity was significantly better, cylindrical error less (0.31 ± 0.36 vs 0.67 ± 0.29, P = 0.05), axial length (AL) smaller (23.68 ± 1.3 vs 24.22 ± 1.6, P = 0.05), Strehl ratio higher (0.08 ± 0.08 vs 0.05 ± 0.04, P = 0.03) and mesopic pupil larger (4.3 ± 1.1 vs 3.7 ± 1.05, P = 0.01) among satisfied patients.Residual cylinder, Strehl ratio, halos, mesopic pupil diameter and UNVA were significant predictors of patient satisfaction. Uncorrected distance visual acuity, higher order Strehl ratio and pupil diameter were significant predictors of halos. Near visual acuity significantly correlated (P = 0.018, R = 0.22) with axial length.
Conclusions
Uncorrected cylindrical error, poor reading quality, larger pupil and halos seem to be the most disturbing factors for patients implanted with the Tecnis Symfony IOL.
目的评价Tecnis Symfony多焦人工晶体植入术后患者的满意度。方法对60例老年性白内障患者120眼行双侧人工晶状体植入术。术后6个月随访。主要结果测量包括未矫正和矫正的远近视力、明显屈光和视觉质量指标。根据主观症状将患者分为满意组和不满意组。ResultsUncorrected中间(0.15±0.11 vs 0.18±0.01,P = 0.04)和附近的(0.26±0.12 vs 0.31±0.11,P = 0.04) (UIVA UNVA)日志3月视力明显更好,圆柱形错误更少的(0.31±0.36 vs 0.67±0.29,P = 0.05),轴向长度(AL)小(23.68±1.3 vs 24.22±1.6,P = 0.05), Strehl率较高(0.08±0.08 vs 0.05±0.04,P = 0.03)和黄昏黎明瞳孔较大(4.3±1.1 vs 3.7±1.05,P = 0.01)在满足病人。残柱面、施特雷氏比、光晕、介视瞳孔直径和UNVA是患者满意度的显著预测因子。未校正距离视力、高阶Strehl比和瞳孔直径是光晕发生的显著预测因子。近视力与眼轴长度显著相关(P = 0.018, R = 0.22)。结论未矫正的柱形误差、阅读质量差、瞳孔较大和光晕是影响Tecnis Symfony人工晶状体植入术的主要因素。
{"title":"The relationship between patient satisfaction and visual and optical outcome after bilateral implantation of an extended depth of focus multifocal intraocular lens","authors":"Kata Miháltz , Stephan Szegedi , Jolanda Steininger , Pia Veronika Vécsei-Marlovits","doi":"10.1016/j.aopr.2022.100043","DOIUrl":"10.1016/j.aopr.2022.100043","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate patient satisfaction after implantation of the Tecnis Symfony multifocal intraocular lens (MIOL).</p></div><div><h3>Methods</h3><p>120 eyes of 60 subjects with senile cataract were bilaterally implanted with the Tecnis Symfony IOL. Follow-up examination was performed 6 months postoperatively. Main outcome measures included uncorrected and corrected distance and near visual acuity, manifest refraction, and visual quality metrics. According to their subjective symptoms patient were divided in two groups: satisfied and unsatisfied.</p></div><div><h3>Results</h3><p>Uncorrected intermediate (0.15 ± 0.11 vs 0.18 ± 0.01, <em>P</em> = 0.04) and near (0.26 ± 0.12 vs 0.31 ± 0.11, <em>P</em> = 0.04) (UIVA, UNVA) log MAR visual acuity was significantly better, cylindrical error less (0.31 ± 0.36 vs 0.67 ± 0.29, <em>P</em> = 0.05), axial length (AL) smaller (23.68 ± 1.3 vs 24.22 ± 1.6, <em>P</em> = 0.05), Strehl ratio higher (0.08 ± 0.08 vs 0.05 ± 0.04, <em>P</em> = 0.03) and mesopic pupil larger (4.3 ± 1.1 vs 3.7 ± 1.05, <em>P</em> = 0.01) among satisfied patients.Residual cylinder, Strehl ratio, halos, mesopic pupil diameter and UNVA were significant predictors of patient satisfaction. Uncorrected distance visual acuity, higher order Strehl ratio and pupil diameter were significant predictors of halos. Near visual acuity significantly correlated (<em>P</em> = 0.018, R = 0.22) with axial length.</p></div><div><h3>Conclusions</h3><p>Uncorrected cylindrical error, poor reading quality, larger pupil and halos seem to be the most disturbing factors for patients implanted with the Tecnis Symfony IOL.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/6e/main.PMC10577816.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1016/S2667-3762(22)00033-6
{"title":"TOC","authors":"","doi":"10.1016/S2667-3762(22)00033-6","DOIUrl":"https://doi.org/10.1016/S2667-3762(22)00033-6","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667376222000336/pdfft?md5=f0f2bd369099fc71a250039709c28c6c&pid=1-s2.0-S2667376222000336-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137043517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1016/j.aopr.2022.100042
Yanan Zhu , Yueyang Zhong , Yanyan Fu
Background
Presbyopia has become a global disease affecting the world's aging population. Among various treatments, cataract extraction and intraocular lens (IOL) implantation have become the most popular and common methods of presbyopia correction. During the twentieth century, IOLs have underwent significant innovation and advancements to meet the patients' high demands for functional vision at all distances.
Main Text
To meet the increasing needs for excellent near and intermediate vision for daily activities, some premium IOLs with more than one focus have been developed, for example, the refractive MfIOLs, diffractive MfIOLs, extended depth of field (EDOF) IOLs, and accommodating IOLs (AIOLs) were introduced to meet this need. In addition, the add-on MfIOLs have been explored as promising supplementary IOLs for pseudophakic presbyopia. When selecting the MfIOLs, the IOLs' features, patients’ characteristics, preoperative eye conditions, and treatment expectations should be considered.
Conclusions
In this review, we focus on the multifocal IOLs (MfIOLs) commonly used for presbyopia correction and systematically summarized their optical designs and clinical outcomes. More evidence-based studies are required to provide guidelines for MfIOL selection, provide maximum visual benefits, and develop personalized visual solutions in the future.
{"title":"The effects of premium intraocular lenses on presbyopia treatments","authors":"Yanan Zhu , Yueyang Zhong , Yanyan Fu","doi":"10.1016/j.aopr.2022.100042","DOIUrl":"10.1016/j.aopr.2022.100042","url":null,"abstract":"<div><h3>Background</h3><p>Presbyopia has become a global disease affecting the world's aging population. Among various treatments, cataract extraction and intraocular lens (IOL) implantation have become the most popular and common methods of presbyopia correction. During the twentieth century, IOLs have underwent significant innovation and advancements to meet the patients' high demands for functional vision at all distances.</p></div><div><h3>Main Text</h3><p>To meet the increasing needs for excellent near and intermediate vision for daily activities, some premium IOLs with more than one focus have been developed, for example, the refractive MfIOLs, diffractive MfIOLs, extended depth of field (EDOF) IOLs, and accommodating IOLs (AIOLs) were introduced to meet this need. In addition, the add-on MfIOLs have been explored as promising supplementary IOLs for pseudophakic presbyopia. When selecting the MfIOLs, the IOLs' features, patients’ characteristics, preoperative eye conditions, and treatment expectations should be considered.</p></div><div><h3>Conclusions</h3><p>In this review, we focus on the multifocal IOLs (MfIOLs) commonly used for presbyopia correction and systematically summarized their optical designs and clinical outcomes. More evidence-based studies are required to provide guidelines for MfIOL selection, provide maximum visual benefits, and develop personalized visual solutions in the future.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/87/main.PMC10577869.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1016/j.aopr.2022.100045
Shiu Yuen Kwok MD, PhD, JD
{"title":"A simple procedure for involutional ectropion repair","authors":"Shiu Yuen Kwok MD, PhD, JD","doi":"10.1016/j.aopr.2022.100045","DOIUrl":"10.1016/j.aopr.2022.100045","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/d7/main.PMC10577813.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1016/j.aopr.2022.100027
Jingjie Xu , Xinyi Chen , Hanle Wang , Ke Yao
Purpose
To compare the complications of femtosecond laser-assisted cataract surgery (FLACS) with those of conventional phacoemulsification surgery (CPS) for age-related cataracts.
Methods
PubMed, Cochrane Library, and EMBASE were systematically searched for studies comparing FLACS and CPS. Outcomes were operative complications, including the intraoperative capsule tear, postoperative corneal edema, macular edema, uncontrolled IOP, etc. The effect measures were weighted with odds ratios with 95% CIs.
Results
Nineteen RCTs and 18 cohort studies, including 24,806 eyes (11,375 of the FLACS group and 13,431 of the CPS group), were identified. There were no significant differences between the two groups in anterior capsule tear, corneal edema, macular edema, uncontrolled IOP, vitreous loss, posterior vitreous detachment, etc. Posterior capsule tear rate showed a significantly lower in RCT subgroups (P = 0.04) and without differences in total (P = 0.63). Significant differences were observed in the incidence of descemet membrane tear/trauma (P = 0.02) and IFIS/iris trauma (P = 0.04. Additionally, The FLACS specific complications showed a significantly higher rate of miosis (P < 0.0001), corneal epithelial defect (P = 0.001), corneal haze (P = 0.002), and subconjunctival hemorrhage (P = 0.01).
Conclusions
FLACS maintains the same safety compared with CPS in terms of all intraoperative and postoperative complications. Although FLACS did show a statistically significant difference for several FLACS specific complications, it would not influence the visual outcome and heal itself.
{"title":"Safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: A meta-analysis and systematic review","authors":"Jingjie Xu , Xinyi Chen , Hanle Wang , Ke Yao","doi":"10.1016/j.aopr.2022.100027","DOIUrl":"10.1016/j.aopr.2022.100027","url":null,"abstract":"<div><h3>Purpose</h3><p>To compare the complications of femtosecond laser-assisted cataract surgery (FLACS) with those of conventional phacoemulsification surgery (CPS) for age-related cataracts.</p></div><div><h3>Methods</h3><p>PubMed, Cochrane Library, and EMBASE were systematically searched for studies comparing FLACS and CPS. Outcomes were operative complications, including the intraoperative capsule tear, postoperative corneal edema, macular edema, uncontrolled IOP, etc. The effect measures were weighted with odds ratios with 95% CIs.</p></div><div><h3>Results</h3><p>Nineteen RCTs and 18 cohort studies, including 24,806 eyes (11,375 of the FLACS group and 13,431 of the CPS group), were identified. There were no significant differences between the two groups in anterior capsule tear, corneal edema, macular edema, uncontrolled IOP, vitreous loss, posterior vitreous detachment, etc. Posterior capsule tear rate showed a significantly lower in RCT subgroups (<em>P</em> = 0.04) and without differences in total (<em>P</em> = 0.63). Significant differences were observed in the incidence of descemet membrane tear/trauma (<em>P</em> = 0.02) and IFIS/iris trauma (<em>P</em> = 0.04. Additionally, The FLACS specific complications showed a significantly higher rate of miosis (<em>P</em> < 0.0001), corneal epithelial defect (<em>P</em> = 0.001), corneal haze (<em>P</em> = 0.002), and subconjunctival hemorrhage (<em>P</em> = 0.01).</p></div><div><h3>Conclusions</h3><p>FLACS maintains the same safety compared with CPS in terms of all intraoperative and postoperative complications. Although FLACS did show a statistically significant difference for several FLACS specific complications, it would not influence the visual outcome and heal itself.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/f6/main.PMC10577854.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1016/j.aopr.2022.100044
Vitaly Potemkin, Sergey Astakhov, Elena Goltsman, Van Syao Yuan
{"title":"Limbal mini-pockets for transscleral IOL fixation","authors":"Vitaly Potemkin, Sergey Astakhov, Elena Goltsman, Van Syao Yuan","doi":"10.1016/j.aopr.2022.100044","DOIUrl":"10.1016/j.aopr.2022.100044","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/72/main.PMC10577843.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1016/j.aopr.2022.100025
Xin Zhang
{"title":"Myelin oligodendrocyte glycoprotein antibody-associated disease following DTaP vaccination: A case report","authors":"Xin Zhang","doi":"10.1016/j.aopr.2022.100025","DOIUrl":"10.1016/j.aopr.2022.100025","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/60/main.PMC10577830.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To evaluate the relationship between axial length (AL) and spherical equivalent refraction (SER) in Chinese children.
Methods
This hospital-based cross-sectional study included 1208 eyes (from 617 Chinese boys and 591 Chinese girls), ranging between 2 and 12 years. All subjects were divided into subgroups according to the spherical equivalent refraction (SER) (hyperopia, emmetropia, and myopia) and age (2–6 years, 7–9 years, and 10–12 years). Comparisons were made between age, sex, and SER groups. Multiple linear regression analysis was used to evaluate the correlation of AL and SER for all groups.
Results
The mean AL and SER were significantly different among the three age groups: 2–6 years group (AL: 22.24 ± 1.59 mm; SER: 0.73 ± 2.67 D); 7–9 years group (AL: 23.49 ± 1.10 mm; SE: -0.68 ± 1.97 D) and 10–12 years group (AL: 24.33 ± 1.02 mm; SER: -1.72 ± 1.86 D). Boys showed longer AL compared with the girls (23.66 ± 1.51 mm vs 23.05 ± 1.32 mm). However, as for SER, the girls (−0.70 ± 2.17 D) showed smaller SER (more myopia) compared with the boys (−0.4 ± 2.48 D). After adjusting for age and sex, the SER tended to decrease (became more myopic) 1.23 D (95% CI: 1.15–1.30D) with a 1 mm increase of AL. Among the different SER groups, the SER tended to become more myopic per mm of AL by 1.09 D (95% CI: 0.97–1.21D) for the myopia group, 1.38 D (95% CI: 1.23–1.54 D) for the hyperopia group, and 0.05 D (95% CI: 0.02–0.08 D) for the emmetropic group. In addition, an increase of 1 mm elongation of AL showed a decrease of SER by 1.05 D (95% CI: 0.90–1.20 D) among 2 – 6-year-olds, by 1.40 D (95% CI: 1.30–1.51 D) among 7 – 9-year-olds, and by 1.37 D (95% CI: 1.21–1.52 D) among 10–12-year-olds. As for sexual differences, the girls 1.68 D, (95% CI: 1.57–1.79 D) showed a more significant myopic shift of SER with a 1 mm increase of AL compared with the boys (0.94 D, 95% CI: 0.84–1.04 D).
Conclusions
Our results indicated a strong linear relationship between SER and AL and an early-rising trend of myopia in Chinese children.
{"title":"Relationship between axial length and spherical equivalent refraction in Chinese children","authors":"Shuying Chen, Xin Liu, Xiaotong Sha, Xiaoxia Yang, Xiaoning Yu","doi":"10.1016/j.aopr.2021.100010","DOIUrl":"10.1016/j.aopr.2021.100010","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the relationship between axial length (AL) and spherical equivalent refraction (SER) in Chinese children.</p></div><div><h3>Methods</h3><p>This hospital-based cross-sectional study included 1208 eyes (from 617 Chinese boys and 591 Chinese girls), ranging between 2 and 12 years. All subjects were divided into subgroups according to the spherical equivalent refraction (SER) (hyperopia, emmetropia, and myopia) and age (2–6 years, 7–9 years, and 10–12 years). Comparisons were made between age, sex, and SER groups. Multiple linear regression analysis was used to evaluate the correlation of AL and SER for all groups.</p></div><div><h3>Results</h3><p>The mean AL and SER were significantly different among the three age groups: 2–6 years group (AL: 22.24 ± 1.59 mm; SER: 0.73 ± 2.67 D); 7–9 years group (AL: 23.49 ± 1.10 mm; SE: -0.68 ± 1.97 D) and 10–12 years group (AL: 24.33 ± 1.02 mm; SER: -1.72 ± 1.86 D). Boys showed longer AL compared with the girls (23.66 ± 1.51 mm vs 23.05 ± 1.32 mm). However, as for SER, the girls (−0.70 ± 2.17 D) showed smaller SER (more myopia) compared with the boys (−0.4 ± 2.48 D). After adjusting for age and sex, the SER tended to decrease (became more myopic) 1.23 D (95% CI: 1.15–1.30D) with a 1 mm increase of AL. Among the different SER groups, the SER tended to become more myopic per mm of AL by 1.09 D (95% CI: 0.97–1.21D) for the myopia group, 1.38 D (95% CI: 1.23–1.54 D) for the hyperopia group, and 0.05 D (95% CI: 0.02–0.08 D) for the emmetropic group. In addition, an increase of 1 mm elongation of AL showed a decrease of SER by 1.05 D (95% CI: 0.90–1.20 D) among 2 – 6-year-olds, by 1.40 D (95% CI: 1.30–1.51 D) among 7 – 9-year-olds, and by 1.37 D (95% CI: 1.21–1.52 D) among 10–12-year-olds. As for sexual differences, the girls 1.68 D, (95% CI: 1.57–1.79 D) showed a more significant myopic shift of SER with a 1 mm increase of AL compared with the boys (0.94 D, 95% CI: 0.84–1.04 D).</p></div><div><h3>Conclusions</h3><p>Our results indicated a strong linear relationship between SER and AL and an early-rising trend of myopia in Chinese children.</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/4a/main.PMC10577836.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The barriers to global eye care equity and the role of digital innovations","authors":"Sifan Zheng , Justin Choo , Jessica Chen , Sarala Joshi , Zhaohui Sun","doi":"10.1016/j.aopr.2021.100021","DOIUrl":"10.1016/j.aopr.2021.100021","url":null,"abstract":"","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/06/main.PMC10577845.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1016/j.aopr.2021.100011
Junxia Fu , Yongping Wang , Shaoying Tan , Guangcan Xu , Huanfen Zhou , Quangang Xu , Shihui Wei
Purpose
To investigate the application of critical flicker fusion frequency (CFF) in demyelinating optic neuritis (DON).
Methods
A cross-sectional study. A total of 127 eyes in 69 DON patients and 63 eyes in 33 healthy control (HC) groups were included between January 2021 to September 2021 from Department of Ophthalmology, PLA General Hospital. Patients underwent best-corrected visual acuity (BCVA), visual field, optical coherence tomography (OCT), flash visual evoked potential (F-VEP), and CFF examinations. The affected eyes were divided into aquaporins 4 (AQP4-), myelin oligodendrocyte glycoprotein (MOG-), and double negative DON according to serum antibody; mild, moderate, severe degree visual impairment according to BCVA ≥ 0.5, 0.1-0.5, < 0.1; and 4 groups: < 1, 1 ∼< 3, 3 ∼ < 6 and > 6 months according to time interval from onset to CFF examination. One-way ANOVA was used to perform above subgroup analysis. The correlations between CFF and F-VEP peak time, peak value, BCVA and mean visual filed defect (MD) were analyzed in order via Pearson correlation analysis.
Results
he trichromatic values of red, green, and yellow in DON affected eyes were 21.83 ± 9.03, 23.66 ± 10.21, 24.09 ± 10.77 Hz, respectively, which was significantly reduced compared with the HC group (t = -14.82, -14.22, -14.00; P < 0.001). The subgroup analysis showed no significant difference between different antibody subtypes (P = 0.914 <0.848 <0.604), whereas, a significant decrease of CFF trichromatic value was found in severe visual acuity impairment group (P < 0.001). There was a significant difference in CFF- trichromatic values at different time points (P < 0.001), to be specific, CFF fluctuated under 20Hz within 3 months after onset and tended to be stable around 24-28Hz. Correlation analysis showed that the peak time of F-VEP (r = -0.486, -0.515, -0.526; P < 0.001), BVCA (r = -0.640, -0.659, -0.642; P < 0.001), were negatively correlated with CFF trichromatic values, MD and CFF were positively correlated (r = 0.486, 0.453, 0.476; P = 0.003, 0.006, 0.004).
Conclusions
A significant decrease of CFF value was found in DON-affected eyes, and it has a good correlation with BCVA, MD and latency of F-VEP, and can better reflect the impairment of visual function
{"title":"The clinical application of critical flicker fusion frequency in demyelinating optic neuritis","authors":"Junxia Fu , Yongping Wang , Shaoying Tan , Guangcan Xu , Huanfen Zhou , Quangang Xu , Shihui Wei","doi":"10.1016/j.aopr.2021.100011","DOIUrl":"10.1016/j.aopr.2021.100011","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the application of critical flicker fusion frequency (CFF) in demyelinating optic neuritis (DON).</p></div><div><h3>Methods</h3><p>A cross-sectional study. A total of 127 eyes in 69 DON patients and 63 eyes in 33 healthy control (HC) groups were included between January 2021 to September 2021 from Department of Ophthalmology, PLA General Hospital. Patients underwent best-corrected visual acuity (BCVA), visual field, optical coherence tomography (OCT), flash visual evoked potential (F-VEP), and CFF examinations. The affected eyes were divided into aquaporins 4 (AQP4-), myelin oligodendrocyte glycoprotein (MOG-), and double negative DON according to serum antibody; mild, moderate, severe degree visual impairment according to BCVA ≥ 0.5, 0.1-0.5, < 0.1; and 4 groups: < 1, 1 ∼< 3, 3 ∼ < 6 and > 6 months according to time interval from onset to CFF examination. One-way ANOVA was used to perform above subgroup analysis. The correlations between CFF and F-VEP peak time, peak value, BCVA and mean visual filed defect (MD) were analyzed in order via Pearson correlation analysis.</p></div><div><h3>Results</h3><p>he trichromatic values of red, green, and yellow in DON affected eyes were 21.83 ± 9.03, 23.66 ± 10.21, 24.09 ± 10.77 Hz, respectively, which was significantly reduced compared with the HC group (<em>t</em> = -14.82, -14.22, -14.00; <em>P</em> < 0.001). The subgroup analysis showed no significant difference between different antibody subtypes (<em>P</em> = 0.914 <0.848 <0.604), whereas, a significant decrease of CFF trichromatic value was found in severe visual acuity impairment group (<em>P</em> < 0.001). There was a significant difference in CFF- trichromatic values at different time points (<em>P</em> < 0.001), to be specific, CFF fluctuated under 20Hz within 3 months after onset and tended to be stable around 24-28Hz. Correlation analysis showed that the peak time of F-VEP (<em>r</em> = -0.486, -0.515, -0.526; <em>P</em> < 0.001), BVCA (<em>r</em> = -0.640, -0.659, -0.642; <em>P</em> < 0.001), were negatively correlated with CFF trichromatic values, MD and CFF were positively correlated (<em>r</em> = 0.486, 0.453, 0.476; <em>P</em> = 0.003, 0.006, 0.004).</p></div><div><h3>Conclusions</h3><p>A significant decrease of CFF value was found in DON-affected eyes, and it has a good correlation with BCVA, MD and latency of F-VEP, and can better reflect the impairment of visual function</p></div>","PeriodicalId":72103,"journal":{"name":"Advances in ophthalmology practice and research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/e8/main.PMC10577832.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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