Annals of 3D printed medicine最新文献

Optical and Mechanical Optimization of 3D-Printed Anatomical Models for Medical Education 医学教育用3d打印解剖模型的光学和机械优化

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-12-19 DOI: 10.1016/j.stlm.2025.100224

Adam S. Verga , Kuang-Drew Li , Benjamin Budenstein , Ailey G. Fogel-Bublick , William J. Nicholson , Scott J. Hollister

Anatomical 3D printing holds significant promise in medical education by enabling the creation of anatomically accurate and mechanically realistic models. While tissue-mimicking materials (TMMs) provide haptic feedback for procedural training, their utility is limited by poor optical clarity. This lack of transparency restricts visualization of internal anatomy and tool movement, particularly in procedures like percutaneous coronary intervention (PCI), where spatial awareness is critical. This study aimed to improve the optical clarity of flexible, elastomeric 3D-printed anatomical models without compromising mechanical realism. This study evaluated dip coating of conformal silicone (S_C), conformal acrylic (A_C), conformal polyurethane (P_C), oil-based polyurethane (P_O), and water-based polyurethane (P_W) for their ability to enhance transparency and preserve the mechanical properties of the Stratasys PolyJet material Agilus30Clear. All coatings significantly reduced absorbance at 600 nm, with S_C, A_C and P_C delivering the greatest optical improvements of up to 91%. S_C and P_C best preserved mechanical behavior, remaining within 20% in stiffness and strain at failure, whereas A_C, P_O, and P_W caused significant stiffening and reduced strain to failure. Constitutive nonlinear elastic models including neo-Hookean, Ogden and Holmes-Mow with perfect plasticity were fit to tensile data to facilitate target tissue matching, while comparing strategies for reporting representative properties. Using a transparent left main coronary artery (LMCA) model, we demonstrated real-time guidewire navigation under direct visualization, highlighting the educational utility of the model. These findings have implications beyond medical education, with potential applications in patient-specific surgical planning, preclinical device testing, and reducing reliance on cadavers and fluoroscopy.

解剖3D打印通过创建解剖准确和机械逼真的模型，在医学教育中具有重要的前景。虽然组织模拟材料（TMMs）为程序训练提供触觉反馈，但其应用受到光学清晰度差的限制。这种透明度的缺乏限制了内部解剖和工具运动的可视化，特别是在像经皮冠状动脉介入治疗（PCI）这样的手术中，空间意识是至关重要的。本研究旨在提高柔性、弹性体3d打印解剖模型的光学清晰度，同时不影响机械真实性。本研究评估了共形硅胶（SC）、共形丙烯酸（AC）、共形聚氨酯（PC）、油基聚氨酯（PO）和水性聚氨酯（PW）的浸涂，以提高透明度并保持Stratasys PolyJet材料Agilus30Clear的机械性能。所有涂层都显著降低了600 nm处的吸光度，其中SC、AC和PC的光学性能改善最大，可达91%。SC和PC最好地保持了力学性能，在破坏时刚度和应变保持在20%以内，而AC、PO和PW则显著增强了刚度，破坏时应变降低了。将具有完美塑性的neo-Hookean、Ogden和Holmes-Mow等本构非线性弹性模型与拉伸数据拟合，促进目标组织匹配，并比较报告代表性性能的策略。利用透明左冠状动脉（LMCA）模型，我们展示了直接可视化下导丝实时导航，突出了模型的教育效用。这些发现的意义超出了医学教育，在患者特异性手术计划、临床前设备测试以及减少对尸体和透视的依赖方面具有潜在的应用价值。

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引用次数: 0

Evaluation of patient preference in 3D printed cast and associated cost compared to current standard of care 评估患者对3D打印铸型的偏好以及与当前护理标准相比的相关成本

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-12-18 DOI: 10.1016/j.stlm.2025.100223

Rand Kittani , Alexis Watson , Sydni Silverman , Kaviamuthan Kanakaraju , Jaime Chen , Jose Beltran , Thomas Murphy

Background

Fracture incidence is rising globally, with traditional fiberglass casts commonly used for immobilization despite discomfort and hygiene issues. 3D printed casts offer similar or improved strength, better comfort, and breathability. While patient satisfaction is generally higher, data on cost-effectiveness and willingness to pay remain limited. This study examines patient preferences between 3D printed and traditional casts after being informed of potential benefits and costs.

Methods

A PubMed review (2015–2023) identified 14 relevant studies on 3D printed casts. Cost data were obtained from Medicare/Medicaid and U.S. manufacturers. A patient survey was conducted at a single clinic (Feb 2024–Aug 2025) among individuals treated with fiberglass or plaster casts. Fifty responses were collected and analyzed using Excel.

Results

Of 50 patients, 66 % were under 18 and 44 % had wrist casts. Most rated immobilization as effective (72 %), but 76 % reported hygiene issues. About 78 % were willing to pay for improved fit or hygiene. Private insurance was linked to greater willingness to pay, and a significant correlation was found between unwillingness to pay for both features (p < 0.001).

Discussion

Traditional casts are effective, but hygiene remains a key concern. Most patients were willing to pay for improved fit and hygiene, especially for wrist and elbow injuries. Interest in same-day casting and alternatives to splints was high. 3D printed casts may offer advantages over both fiberglass casts and CAM boots.

在全球范围内，骨折发生率正在上升，尽管存在不适和卫生问题，但传统的玻璃纤维铸件通常用于固定。3D打印铸件提供类似或改进的强度，更好的舒适性和透气性。虽然患者满意度普遍较高，但关于成本效益和支付意愿的数据仍然有限。在被告知潜在的好处和成本后，本研究调查了患者在3D打印和传统铸件之间的偏好。方法PubMed综述（2015-2023）确定了14项关于3D打印模型的相关研究。成本数据来自医疗保险/医疗补助和美国制造商。在单个诊所（2024年2月至2025年8月）对使用玻璃纤维或石膏石膏治疗的患者进行了患者调查。收集50份问卷并使用Excel进行分析。结果50例患者中，66%的患者年龄在18岁以下，44%的患者有手腕石膏。大多数人认为固定有效（72%），但76%的人报告了卫生问题。约78%的人愿意花钱改善健康或卫生状况。私人保险与更大的支付意愿有关，并且在不愿意支付这两个特征之间发现了显著的相关性（p < 0.001）。传统的石膏是有效的，但卫生仍然是一个关键问题。大多数患者愿意为改善健康和卫生状况付费，尤其是手腕和肘部受伤的患者。人们对当天铸造和替代夹板的兴趣很高。3D打印铸件可能比玻璃纤维铸件和CAM靴子都有优势。

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引用次数: 0

Patient-specific guides for minimally invasive sacroiliac joint fusion revision surgery 微创骶髂关节融合翻修手术患者特异性指南

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-12-18 DOI: 10.1016/j.stlm.2025.100225

Danique Smelt , Nick Kampkuiper , Jorm Nellensteijn , Maranda Haenen , Edsko Hekman , Gabriëlle Tuijthof , Femke Schröder , Maaike Koenrades

Introduction

Implant loosening or persistent pain after sacroiliac joint fusion or stabilization surgery may require revision surgery. Accurate and safe implant placement in minimally invasive sacroiliac joint fusion (SIJF) revision surgery is challenging due to limited visibility and restricted space for new implants. A patient-specific guide (PSG) allows customization of implant positioning beyond the traditional parallel configuration generally used in SIJF but has only been applied in open procedures requiring bone exposure. This study presents the implementation and evaluation of a novel PSG for minimally invasive SIJF revision surgery in patients with prior SI fusion or stabilization surgery.

Method

A retrospective cohort study was conducted to evaluate implant placement accuracy using a novel PSG. The guide design was iteratively refined to enhance rigidity and placement accuracy. Postoperative implant positions were compared to the planned positions using 3D deviation analysis. Furthermore, implant malpositioning and other complications were monitored.

Results

Fourteen SIJF revisions were performed, comprising a total of 23 newly placed implants. Implant positioning using PSGs was feasible in all cases, and all implants were placed without malpositioning complications. Accuracy analysis showed a median 3D total positional deviation of 5.3 mm (Q1: 4.8 mm, Q3: 8.3 mm) and a median total 3D angle of 3.7° (Q1: 2.4°, Q3: 5.2°).

Conclusion

The study showed that the developed PSG design for use in minimally invasive SIJF revision surgery is feasible with what is considered a clinically acceptable level of accuracy.

骶髂关节融合或稳定手术后植入物松动或持续疼痛可能需要翻修手术。在微创骶髂关节融合（SIJF）翻修手术中，由于新植入物的可见性和空间有限，准确和安全的植入物放置具有挑战性。患者特异性指南（PSG）允许定制种植体定位，而不是SIJF中通常使用的传统平行配置，但仅适用于需要骨暴露的开放手术。本研究介绍了一种新型PSG在微创SIJF翻修手术中对先前进行过SI融合或稳定手术的患者的实施和评估。方法采用回顾性队列研究评估新型PSG植入体的准确性。迭代改进导轨设计，以提高刚性和放置精度。利用三维偏差分析将术后种植体位置与计划位置进行比较。此外，监测种植体错位及其他并发症。结果共进行了14例SIJF修复，包括23例新放置的种植体。所有病例均可使用psg进行种植体定位，所有种植体均无错位并发症。准确度分析显示，三维总位置偏差中位数为5.3 mm (Q1: 4.8 mm, Q3: 8.3 mm)，三维总角度中位数为3.7°（Q1: 2.4°，Q3: 5.2°）。结论：该研究表明，开发的PSG设计用于微创SIJF翻修手术是可行的，并且具有临床可接受的准确性。

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引用次数: 0

Next-gen heart solutions: 3D bioprinting and AI in valve replacement therapy 下一代心脏解决方案：3D生物打印和人工智能在瓣膜置换治疗中的应用

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-08-19 DOI: 10.1016/j.stlm.2025.100219

Saddik Haddad , Ahmad․Amr Karzoun , Lutfallah Raffoul , Yazan Mohamed , Suzana Sultan , Aram Abbas , Basem Zaino

The rising incidence of valvular heart disease (VHD) poses a significant challenge in cardiovascular care, particularly as many patients face severe cases where valve repair is no longer an option. In these instances, valve replacement with mechanical and biological prosthetic valves is a common approach. However, this treatment often leads to complications, including a notably high recurrence of thrombosis and bleeding associated with prosthetic valves. Addressing these complications is critical, as various factors can adversely affect valvular function after replacement.

To combat these issues, emerging technologies such as 3D bioprinting and artificial intelligence (AI) offer promising solutions. This review explores how the integration of 3D bioprinting and AI can facilitate the development of anticoagulant-free heart valve replacements. By leveraging predictive models, these technologies can identify high-risk individuals prior to surgery and optimize postoperative care, thereby increasing the likelihood of successful prosthetic valve performance and enhancing the overall quality of life for patients.

瓣膜性心脏病（VHD）发病率的上升对心血管护理提出了重大挑战，特别是当许多患者面临瓣膜修复不再是一种选择的严重情况时。在这些情况下，用机械和生物假体瓣膜置换是常见的方法。然而，这种治疗经常导致并发症，包括与人工瓣膜相关的血栓和出血的明显高复发率。处理这些并发症是至关重要的，因为各种因素会对置换术后的瓣膜功能产生不利影响。为了解决这些问题，3D生物打印和人工智能（AI）等新兴技术提供了有希望的解决方案。本文探讨了3D生物打印和人工智能的结合如何促进无抗凝血心脏瓣膜替代物的发展。通过利用预测模型，这些技术可以在手术前识别高危人群并优化术后护理，从而增加人工瓣膜成功的可能性，提高患者的整体生活质量。

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引用次数: 0

Impact of dry heat sterilization on the mechanical and functional performance of 3D printed medical devices for image-guided intervention 干热灭菌对用于图像引导干预的3D打印医疗设备机械和功能性能的影响

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-07-02 DOI: 10.1016/j.stlm.2025.100216

Mary Chase Sheehan , Sarah Kim , Sunandita Sarker , Govindarajan Srimathveeravalli

Polymer additive manufacturing (AM) is a powerful method for medical device prototyping, producing low-cost medical devices for resource limited settings and patient-specific customization. Plastic medical devices created with AM must undergo sterilization prior to in vivo experiments or use with patients. While prior studies have verified the feasibility and safety of sterilization of such devices, the impact on mechanical performance has not been studied. Temperatures during autoclave sterilization, a commonly used and widely available method, can match or exceed the melt temperature of Nylon-12 used for selective laser sintering. Here we tested the impact of single or multiple cycles of autoclave sterilization on the mechanical and functional performance of plastic components used with interventional radiology related medical devices (catheter hub, ablation probe handle, and implantable port). We found that up to 2 cycles of sterilization did not tangibly impact the manufacturability, function or surface finish of these devices. However, we found that more than one cycle of sterilization can compromise the mechanical strength of the devices, with geometric-linked variations in the level of change in stiffness (ranging from 12 – 23 %). In conclusion, autoclave sterilization is safe for single use AM medical devices, where repetition of the sterilization for device reuse can compromise mechanical performance.

聚合物增材制造（AM）是一种强大的医疗设备原型制造方法，可以为资源有限的环境和特定患者定制生产低成本的医疗设备。用AM制造的塑料医疗器械必须在体内实验或与患者一起使用之前进行灭菌。虽然先前的研究已经验证了此类装置灭菌的可行性和安全性，但尚未研究其对机械性能的影响。高压灭菌器灭菌是一种常用和广泛可用的方法，其温度可以匹配或超过用于选择性激光烧结的尼龙-12的熔体温度。在这里，我们测试了单次或多次高压灭菌器灭菌对用于介入放射学相关医疗设备（导管毂、消融探头手柄和植入端口）的塑料部件的机械和功能性能的影响。我们发现长达2次的灭菌对这些设备的可制造性、功能或表面光洁度没有明显的影响。然而，我们发现，超过一个灭菌周期会损害设备的机械强度，在刚度变化水平的几何相关变化（范围从12 - 23%）。总之，高压灭菌器灭菌对于一次性使用的AM医疗设备是安全的，其中重复灭菌以重复使用设备可能会损害机械性能。

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引用次数: 0

Improvement of pedicle screw placement with first-time use of patient specific drill guides by novice surgeon 新手外科医生首次使用患者专用钻头导引改善椎弓根螺钉置入

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-06-30 DOI: 10.1016/j.stlm.2025.100215

Kyle Walker , Kunal Verma , Michael Silverstein , David Gurd

Purpose

Accurate placement of pedicle screws is a key component of spine surgery. The goal of this study is to evaluate the accuracy and precision of a 3-dimensional (3D) printed patient-specific instrumentation (PSI) guide in improving pedicle screw trajectory placement for a first-time user.

Methods

A computed tomography scan of a cadaveric spine was obtained and 3D reconstructed virtually. One pedicle at each vertebra was randomized to the PSI or freehand (FH) grouping. Screw trajectories were virtually planned for T1-L5 vertebral levels. A junior orthopaedic surgery resident used the PSI to place a screw at 17 vertebral levels and then returned on a separate day to place screws using FH technique. No adjustments from the initial placement were allowed. Postoperatively the spine was rescanned and analyzed by a blinded senior attending surgeon for perforation, adequacy of placement, and likelihood of unfavorable outcome. The PSI grouping was analyzed objectively for deviation from the preoperative plan.

Results

Five of the FH screws were deemed to likely result in paralysis or major neurovascular injury vs zero in the PSI grouping (p-value 0.045). The mean PSI placement time was 47.9 s faster per level than the FH placement time (145.2 ± 74.4 vs 193.1 ± 43.0 s; p-value 0.032). The PSI trajectories were accurate within 2.75 mm and 9.0 degrees of the planned trajectories (p-value 0.045; p-value 0.036).

Conclusions

The PSI system appears to offer a relatively inexpensive, user-friendly, and sufficiently accurate solution to pedicle screw placement for even a novice surgeon using the technology for the first time.

目的椎弓根螺钉的准确放置是脊柱外科手术的关键组成部分。本研究的目的是评估三维（3D）打印患者专用器械（PSI）指南在改善首次使用者椎弓根螺钉轨迹放置方面的准确性和精密度。方法对尸体脊柱进行计算机断层扫描，并进行虚拟三维重建。每个椎体的一个椎弓根随机分为PSI组或徒手组。在T1-L5椎体水平实际上规划了螺钉轨迹。一名初级骨科住院医师使用PSI在17个椎体水平放置螺钉，然后在另一天使用FH技术放置螺钉。不允许对初始位置进行调整。术后对脊柱进行重新扫描，并由一名盲法资深主治医生对穿孔、放置的适当性和不良结果的可能性进行分析。客观分析PSI分组是否偏离术前计划。结果FH组有5例可能导致瘫痪或严重神经血管损伤，PSI组为0例（p值为0.045）。平均PSI放置时间比FH放置时间快47.9 s(145.2±74.4 vs 193.1±43.0 s)；假定值0.032)。PSI轨迹在计划轨迹的2.75 mm和9.0度范围内准确(p值0.045；假定值0.036)。结论PSI系统似乎提供了一种相对便宜、用户友好且足够准确的椎弓根螺钉置入解决方案，即使是新手外科医生第一次使用该技术。

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引用次数: 0

Applications of 3D printing in the teaching of human anatomy: An integrative review 3D打印技术在人体解剖学教学中的应用综述

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-06-26 DOI: 10.1016/j.stlm.2025.100213

Keila Danira Paim e Silva Cadete Tomás, Maíza Rodrigues Silva, Vanessa Namieh Garicoix, Lilian Navarro Wenceslau Giacometti, Victor Giovanni Ramos Cardoso, Josemar Santos de Matos, Braulio Henrique Magnani Branco, Lucas França Garcia, Audrei Pavanello, Karina Miura da Costa

This study consists of a review that explores the application of three-dimensional (3D) printing in the teaching of human anatomy. A search was conducted in the PubMed, Scopus, and Web of Science databases, using the terms "3D Printing", "Health", "Education", and "Anatomy". Articles published between 2019 and 2024 addressing the use of 3D printing for the production of anatomical models in the teaching of human anatomy were selected. The review included 15 articles, covering printed models from the circulatory, skeletal, nervous, and reproductive systems. 3D printing has been used to create detailed and customized anatomical models, offering three-dimensional visualization, anatomically precise details, and tactile feedback, assisting in memorizing anatomical structures. In addition, 3D printing can stimulate student engagement, resulting in better academic performance. Studies indicate that the novelty of the technology can increase student interest, leading to more effective learning. The customization of printed models allows for specific adaptations to the needs of students, improving the effectiveness of teaching. In conclusion, 3D printing has the potential to overcome the challenges of traditional anatomy teaching. As technology evolves, even more innovative applications in the field of anatomy education are likely to emerge. This study highlights the importance of integrating new technologies into the educational curriculum to improve student understanding and interest in subjects such as human anatomy.

本文就三维打印技术在人体解剖学教学中的应用作一综述。在PubMed， Scopus和Web of Science数据库中进行了搜索，使用术语“3D打印”，“健康”，“教育”和“解剖学”。选择了2019年至2024年间发表的关于在人体解剖学教学中使用3D打印制作解剖模型的文章。该综述包括15篇文章，涵盖了循环系统、骨骼系统、神经系统和生殖系统的打印模型。3D打印已被用于创建详细和定制的解剖模型，提供三维可视化、解剖精确的细节和触觉反馈，帮助记忆解剖结构。此外，3D打印可以激发学生的参与度，从而提高学习成绩。研究表明，技术的新颖性可以提高学生的兴趣，从而更有效地学习。印刷模型的定制允许特定的适应学生的需要，提高教学效率。总之，3D打印具有克服传统解剖学教学挑战的潜力。随着技术的发展，解剖学教育领域可能会出现更多创新的应用。这项研究强调了将新技术整合到教育课程中的重要性，以提高学生对人体解剖学等学科的理解和兴趣。

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引用次数: 0

The future of 3D printing in instrumented implantable polymer meta-stents 3D打印在可植入聚合物支架中的应用前景

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-06-08 DOI: 10.1016/j.stlm.2025.100211

C. Brosseau , G. Nocchiero , J. Ville

An increasing diversity of performance demands are being put on devices for medical applications. These include the need for the best mechanical, thermal, electromagnetic, chemical, and flow properties, biological compatibility, and low weight of such material systems. In this review article, we discuss three features that can confer advantages for new instrumented implementable stents. Firstly, we examine the benefits of using 3D-printed polymer stents by comparing their characteristics with metallic devices. One challenge of designing mechanical metamaterial-based stents is choosing their complex geometric structure. Secondly, we report progress in the design of printed antennas for wireless communication with implantable stents capable of monitoring real-time biological signals. This could be very important for early diagnosis of in-stent restenosis and real-time monitoring of intravascular blood conditions. Thirdly, virtual replica digital twin technology can facilitate personalized stent design based on individual patient characteristics, medical history, and real-time physiological data. This new predictive analysis in healthcare systems relies largely on the use of deep learning algorithms, appropriate for managing massive data integration. Finally, we summarize some of the major outstanding challenges that, if addressed, would move us substantially closer to realizing practically useful instrumented implantable polymer meta-stents that are integrated systems. Looking to the future, the conclusions of this review will be beneficial for researchers, clinicians, and engineers in the development and application of 3D printing for improved instrumented polymer stents.

对医疗应用设备的性能要求越来越多样化。这些包括需要最好的机械、热、电磁、化学和流动性能，生物相容性，以及这种材料系统的低重量。在这篇综述文章中，我们讨论了可以赋予新的器械支架优势的三个特征。首先，我们通过比较3d打印聚合物支架与金属支架的特性来研究使用3d打印聚合物支架的好处。设计机械超材料支架的挑战之一是选择其复杂的几何结构。其次，我们报告了用于无线通信的印刷天线的设计进展，该天线具有能够监测实时生物信号的植入式支架。这对于支架内再狭窄的早期诊断和血管内血液状况的实时监测非常重要。第三，虚拟复制数字孪生技术可以根据患者个体特征、病史和实时生理数据进行个性化支架设计。医疗保健系统中的这种新的预测分析在很大程度上依赖于深度学习算法的使用，适合管理大量数据集成。最后，我们总结了一些主要的突出挑战，如果这些挑战得到解决，将使我们实质上更接近于实现实际有用的仪器植入聚合物集成支架系统。展望未来，本综述的结论将有助于研究人员、临床医生和工程师在3D打印技术的开发和应用中进行改进。

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引用次数: 0

Pioneering era in paediatric tuberculosis: Utilization of 3D printing technology 儿科结核病的先驱时代：3D打印技术的应用

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-06-08 DOI: 10.1016/j.stlm.2025.100214

Shubham Singh , Mohit Kumar , Deeksha Choudhary , Devesh Kumar , Dikshant , Shital Zambad , Shruti Chopra , Manjeet Bansal , Amit Bhatia

The management of paediatric tuberculosis (TB) poses substantial clinical challenges necessitating innovative approaches. The advent of 3D printing technology has ushered in a pioneering era in paediatric TB care, revolutionizing diagnostics, treatment strategies, and medical education. This abstract explores the multifaceted utilization of 3D printing in addressing these challenges. The 3D printing enables the creation of anatomically accurate models derived from patient-specific imaging data. These models aid clinicians in preoperative planning, facilitating precise surgical interventions for complicated TB cases in children. Such personalized anatomical replicas enhance surgical outcomes by allowing surgeons to simulate procedures and anticipate challenges unique to paediatric TB. Furthermore, 3D printing supports medical education by providing tangible, interactive learning tools. Complex TB pathology and treatment concepts can be visually and haptically represented through 3D printed models, enhancing understanding among healthcare professionals and students. Hands-on training with these models fosters proficiency in paediatric TB management, ensuring competent care delivery. Using 3D printing technology marks a transformative shift in paediatric TB management, offering personalized treatment modalities, enhancing surgical precision, and advancing medical education. As this technology continues to evolve, its integration into clinical practice holds promise for improving outcomes and quality of life for young TB patients globally. In this paper, the authors underscore the significant contributions of 3D printing in shaping the future of paediatric TB care, illustrating its potential to redefine standards in paediatric infectious disease management.

儿科结核病（TB）的管理提出了重大的临床挑战，需要创新的方法。3D打印技术的出现开创了儿科结核病治疗的先驱时代，彻底改变了诊断、治疗策略和医学教育。这个摘要探讨了3D打印在解决这些挑战的多方面的利用。3D打印可以根据患者特定的成像数据创建解剖学上准确的模型。这些模型有助于临床医生进行术前规划，促进对复杂的儿童结核病病例进行精确的手术干预。这种个性化的解剖复制品通过允许外科医生模拟手术过程和预测儿科结核病特有的挑战来提高手术效果。此外，3D打印通过提供有形的、互动的学习工具来支持医学教育。通过3D打印模型，可以直观和触觉地呈现复杂的结核病病理和治疗概念，从而增强医疗保健专业人员和学生之间的理解。使用这些模式进行的实践培训有助于提高儿科结核病管理的熟练程度，确保提供合格的医疗服务。使用3D打印技术标志着儿科结核病管理的革命性转变，提供个性化的治疗方式，提高手术精度，并推进医学教育。随着这项技术的不断发展，将其纳入临床实践有望改善全球年轻结核病患者的预后和生活质量。在本文中，作者强调了3D打印在塑造儿科结核病治疗未来方面的重要贡献，说明了其重新定义儿科传染病管理标准的潜力。

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引用次数: 0

Novel 3D printed jig design for a smooth and accurate dome osteotomy: A case report 新颖的3D打印夹具设计为一个平滑和准确的圆顶截骨：一个案例报告

Q3 Medicine

Annals of 3D printed medicine

Pub Date : 2025-06-06 DOI: 10.1016/j.stlm.2025.100210

Ervin Sethi, Sze Ern Tan, Michael Yam

Femoral malunion with associated sagittal and coronal deformity poses significant challenges in achieving anatomical realignment and functional restoration. This case report describes a novel surgical technique utilizing patient-specific 3D planning and a custom-designed, 3D-printed curved cutting jig to perform a dome osteotomy for deformity correction in a 69-year-old male with a history of childhood femoral fracture and recent atypical femoral fracture associated with bisphosphonate use. Preoperative CT-based 3D modeling allowed accurate assessment of the deformity and precise planning of the osteotomy. A customized jig was engineered with a hemispherical slot to guide a smooth curved osteotomy, enabling biplanar correction while preserving limb length and optimizing bony contact for healing. Intraoperative execution was streamlined by jig-guided drilling and osteotomy, followed by intramedullary nail fixation. Postoperative recovery was uneventful, with early mobilization and successful alignment and union confirmed radiographically. This approach demonstrated the value of advanced 3D technologies in enhancing surgical precision, reducing operative time and radiation exposure, and improving clinical outcomes. It represents a promising option for complex femoral deformity correction when institutional resources permit.

股骨畸形愈合伴矢状和冠状畸形是实现解剖重组和功能恢复的重大挑战。本病例报告描述了一种新颖的手术技术，利用患者特定的3D规划和定制设计的3D打印弯曲切割治具，对一名69岁男性患者进行穹状截骨手术，该患者患有儿童期股骨骨折和近期非典型股骨骨折，并使用双膦酸盐。术前基于ct的3D建模可以准确评估畸形和精确规划截骨。一个定制的夹具被设计成半球形槽来引导平滑弯曲的截骨，在保持肢体长度和优化骨接触愈合的同时实现双平面矫正。术中执行通过夹具引导钻孔和截骨，然后髓内钉固定。术后恢复顺利，早期活动和放射学证实成功对准和愈合。这种方法证明了先进的3D技术在提高手术精度、减少手术时间和辐射暴露以及改善临床结果方面的价值。当机构资源允许时，它代表了复杂股骨畸形矫正的一个有希望的选择。

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