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Visceral leishmaniasis in a 10-month-old Austrian girl Epidemiological Aspects and Treatment Strategies with review of the Iiterature 10个月奥地利女孩内脏利什曼病流行病学方面和治疗策略与文献回顾
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550627
H. Dornbusch, T. Perwein, Petra Ritter-Sovinz, C. Urban
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引用次数: 0
Promoting Health Students’ Well-Being: The Study Protocol of a Quasi-Experimental Intervention Study 促进健康学生幸福感:一项准实验干预研究的研究方案
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550629
El Ouazzani, Houria,, Bourdaire Christiane, Picard Angélique, Gazaix Lena
Introduction: Several studies identified high prevalence of anxiety, stress, and depression for health students, including paramedic students. For this reason, the health students’ well-being represents a public health issue. To improve this situation, we need to develop interventions at the beginning of health studies. The implementation of occasional and/or regular well-being promotion interventions meets a real need for many of health students. Objectives of this study: We aim to assess a well-being promotion intervention among paramedic students in Le Havre (France). Methods and analysis: This is a protocol of monocentric quasi-experimental study designed to assess the impact of the intervention on well-being, resilience, self-esteem, and stress among paramedic students throw validated scales distributed before the intervention and 8 months after. Students’ satisfaction will be assessed through a questionnaire. A first analysis will describe the study population. The comparison of average scores will be performed. The results of satisfaction questionnaire will allow evolving the intervention to best meet the needs of students next year. Discussion: The scientific publications on this theme will enrich the literature and contribute to the integration of this approach of well-being promotion nationally and internationally. The expected benefits from this study are the adoption of a healthy lifestyle, the improvement of students’ well-being and their awareness of the importance of health promotion in patients’ care. Ethics and dissemination: The project received ethical approval from the Research Ethics Board of Le Havre Hospital. The results will be disseminated via scientific publications and conference presentations.
几项研究发现,焦虑、压力和抑郁在健康专业的学生中普遍存在,包括护理专业的学生。因此,健康学生的健康是一个公共健康问题。为了改善这种情况,我们需要在健康研究开始时制定干预措施。实施偶尔和(或)定期的福祉促进干预措施满足了许多卫生专业学生的实际需要。本研究的目的:我们旨在评估勒阿弗尔(法国)护理学生的福祉促进干预。方法与分析:本研究采用单中心准实验研究方案,通过干预前和干预后8个月发放的有效量表,评估干预对护理专业学生幸福感、恢复力、自尊和压力的影响。学生的满意度将通过问卷进行评估。第一次分析将描述研究人群。将进行平均分数的比较。满意度调查问卷的结果将有助于改进明年的干预措施,以最好地满足学生的需求。讨论:关于这一主题的科学出版物将丰富文献,并有助于在国内和国际上整合这种促进福祉的方法。本研究的预期效益是采用健康的生活方式,改善学生的幸福感,并提高他们对患者护理中健康促进重要性的认识。伦理和传播:该项目获得了勒阿弗尔医院研究伦理委员会的伦理批准。研究结果将通过科学出版物和会议报告进行传播。
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引用次数: 0
Virlaza™ Improves Lung Function, Mechanics and Inflammation and Muscle Strength of Post-Covid-19 Patient: A Case Report Virlaza™改善covid -19后患者的肺功能、力学、炎症和肌肉力量:一份病例报告
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550630
Maysa Alves Rodrigues Brandao-Rangel, D. Melamed, C. Frison, Razi Ronen, B. Brill, R. P. Vieira
Archives
档案
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引用次数: 0
Reconstruction of the Lower Lip with A Buccal Fat Pad Free Graft– Report of A Case 无颊脂肪垫移植重建下唇1例报告
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550632
Fares Kablan, Daniel Oren, Asaf Zigron, Khaldoon Abu Saleh, Idan Redenski, Samer Srouji
,
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引用次数: 0
Multi-System Inflammatory Syndrome in Children (MIS-C) with Retropharyngeal Involvement Mimicking Abscess: the Therapeutic Role of Anakinra. 儿童多系统炎症综合征(MIS-C)伴咽后浸润模拟脓肿:阿那白的治疗作用。
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550577
Angela Troisi, Francesco Accomando, Lorenzo Mambelli, Federico Marchetti

Multi-System Inflammatory Syndrome in Children (MIS-C) is a new diagnostic entity that appeared with the Covid-19 pandemic, and that only concerns the pediatric age. Early diagnosis and early immunomodulatory treatment lead most of the time to a complete resolution of the pathology. We present a case of MIS-C, whose main clinical feature was neck pain due to inflammation of retropharyngeal tissues. The use of anakinra was critical for healing.

儿童多系统炎症综合征(Multi-System Inflammatory Syndrome in Children, MIS-C)是随着Covid-19大流行而出现的一种新的诊断实体,仅涉及儿童年龄。早期诊断和早期免疫调节治疗大部分时间导致病理完全解决。我们报告一例MIS-C,其主要临床特征是由于咽后组织炎症引起的颈部疼痛。阿那白的使用对愈合至关重要。
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引用次数: 1
Manifestation of High Endogenous Heparinization in Postpartum Hemorrhage Patient using Thromboelastography: New Avenue of Coagulopathy Monitoring 产后出血患者高内源性肝素化的血栓弹性成像表现:凝血功能监测的新途径
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550578
T. Yan, He Fei, Changfu Ji, Lai Dong, Ching-Feng Weng
Background: Postpartum hemorrhage (PPH) is a leading cause of severe maternal morbidity and mortality worldwide which leads to massive blood loss. Coagulation abnormalities in response to severe trauma or infection are a latent cause that might aggravate PPH. Case Presentation: A 39-week menolipsis of a 26-year-old puerpera appeared lacking amniotic fluid and uterine infection after examination. During the cesarean section, the patient manifested fever, massive hemorrhage, and shock. The low coagulation of the PPH patient was diagnosed by thromboelastography (TEG) guided with heparinase (type I). According to the sequential monitoring via the TEG guided assay, the coagulopathy and hyper-heparinization were obviously shown. Concurrent protamine correction for the patient’s coagulation abnormality gradually resulted in a stable condition after 4 hours of emergent treatment. This setting revealed that TEG-guided determination of endogenous heparin and subsequent infusion of protamine effectively reverted the syndrome of PPH. Conclusions: This is an investigation of the PPH syndrome with infection patient suggests that hyper-endogenous heparinization should be clinically taken into consideration for low coagulation.
背景:产后出血(PPH)是世界范围内孕产妇严重发病和死亡的主要原因。严重创伤或感染引起的凝血异常是可能加重PPH的潜在原因。病例介绍:一位26岁的产妇绝经39周,检查后出现羊水不足和子宫感染。剖宫产时,患者出现发热、大出血、休克等症状。采用肝素酶(I型)引导下的血栓弹性成像(TEG)诊断PPH患者的低凝。通过TEG引导下的连续监测,明显显示凝血功能障碍和高肝素化。同时对患者凝血异常进行鱼精蛋白矫正,经紧急治疗4小时后病情逐渐稳定。这一设置表明,teg引导的内源性肝素测定和随后的鱼精蛋白输注有效地恢复了PPH综合征。结论:本研究是对PPH综合征合并感染患者的一项调查,提示临床上应考虑超内源性肝素化治疗低凝。
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引用次数: 0
Pharmacist’s Comprehensive Medication Review in Deprescribing Chronic Medications at the End of Life 生命末期慢性药物处方的药师综合用药回顾
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550580
Selina Muhn, Nishita Shah Amin, C. Bardolia, J. Turgeon, Jill Shanor, V. Michaud
Studies
研究
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引用次数: 1
Evaluation of a Novel External Neuromodulation Device (iCLEAR™) for the Acute Relief of Rhinitis and Rhinosinusitis Symptoms 一种新型体外神经调节装置(iCLEAR™)用于急性缓解鼻炎和鼻窦炎症状的评估
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550582
MD E. Mark Shusterman, MD Michael E. Gertner, MD Anita Carmen Choy, MD Jacob Johnson, Neil J. Friedman, Welch-Pasteur Allergy, Mark Shusterman
Methods: This was a multicenter, open-label, single-arm, clinical trial which included adult patients with nasal obstructive symptoms due to chronic rhinitis/rhinosinusitis and a minimum Visual Analog Scale (VAS) score of 25 mm and/or a minimum raw Nasal Obstruction Symptom Evaluation (NOSE) score of 2 on any of items 1, 2, 3, or 5. Enrolled subjects were instructed to apply the study device bilaterally to the external nasal nerve at least three times per day for 30 seconds until the 2-week followup, then twice per day and as needed thereafter. Subjects were evaluated at Days 3, 14, and 30 following the initial baseline visit. The primary efficacy endpoint was the change in nasal obstructive symptoms from baseline to Day 30 as measured by the VAS and NOSE instruments. Safety was assessed by the incidence of device-related Adverse Events (AEs).
方法:这是一项多中心、开放标签、单臂临床试验,纳入了由慢性鼻炎/鼻窦炎引起的鼻塞症状的成年患者,最低视觉模拟量表(VAS)评分为25 mm和/或最低原始鼻塞症状评估(NOSE)评分为2,其中任何项目1、2、3或5。被招募的受试者被要求每天至少三次将研究装置应用于双侧鼻外神经,持续30秒,直到2周的随访,然后每天两次,之后根据需要。在首次基线访问后的第3、14和30天对受试者进行评估。主要疗效终点是通过VAS和NOSE仪器测量的从基线到第30天鼻塞症状的变化。安全性通过器械相关不良事件(ae)的发生率进行评估。
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引用次数: 0
Rapid Development of a Giant Cardiac Myxoma in a Patient with Carney syndrome: a Case Report 卡尼综合征患者迅速发展为巨大心脏黏液瘤1例报告
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550598
Messi P, Benzoni G, B. G., Fatti L, H. F., Badano L, Fratianni G, Moneta A, Donatelli F
Carney Complex Syndrome is a rare genetic disorder that affects multiple organs and systems, including the endocrine glands, heart, and skin. The transmission of the syndrome is autosomal dominant, the gene involved in the mutation, in more than 60% of cases, is the PRKAR1A gene. We aim to present a 38-year-old female diagnosed with Carney syndrome since 2011. During April 2022, according to the cardiac screening plan, she underwent a transthoracic echocardiography, which did not show any cardiac tumors. However, in December 2022, the patient reported symptoms like dyspnea and palpitations. Immediately a new transthoracic echocardiography was performed, which revealed a large oval mass with heterogeneous echotexture and irregular margins in the left atrium, with a broad base of implantation at the interatrial septum, measuring 5 × 5, 5 cm. The mass cause obstruction to filling because was engaging in systole in the left ventricle. Additionally, a PFO, a common anatomical variant of interatrial septum, was found. The patient underwent cardiothoracic surgery to remove the myxoma and close the PFO via right mini thoracotomy, few days after. The surgery was successful, and the patient had good results in subsequent follow-up. In this article we aim to focus attention on the need to perform echocardiographic follow-up in a short time in patient with a familiar history of neoplasm involving myxoma, to preserve the patient from major compliances, especially reduce the risk of sudden cardiac death.
卡尼复杂综合征是一种罕见的遗传性疾病,会影响多个器官和系统,包括内分泌腺、心脏和皮肤。该综合征的传播是常染色体显性的,参与突变的基因,在60%以上的病例中,是PRKAR1A基因。我们的目标是介绍一位38岁的女性,自2011年以来被诊断为卡尼综合征。2022年4月,根据心脏筛查计划,她接受了经胸超声心动图检查,未发现任何心脏肿瘤。然而,在2022年12月,患者报告了呼吸困难和心悸等症状。立即行新的经胸超声心动图,发现左心房有一个大的椭圆形肿块,回声不均匀,边缘不规则,在房间隔处有一个宽的植入基部,尺寸为5 × 5,5 cm。肿块在左心室收缩,导致充盈受阻。此外,PFO,常见的解剖变异的房间隔,被发现。几天后,患者接受了心胸外科手术切除黏液瘤,并通过右小开胸术关闭PFO。手术成功,患者后续随访效果良好。在这篇文章中,我们的目的是关注在短时间内对有黏液瘤病史的患者进行超声心动图随访的必要性,以保护患者免于主要依从性,特别是降低心源性猝死的风险。
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引用次数: 0
Hematological and Biochemical Parameters as Prognostic Markers of COVID-19 Disease Progression in Hospitalized Patients: A Study in Gabon 血液学和生化参数作为住院患者COVID-19疾病进展的预后指标:加蓬研究
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550601
Berthe A. Iroungou, Larson Boundenga, Edith Sylvie Manga Manguiya, Aurore Pryslya Bouassa, J. Nzenze, Guignali Laurette Mangouka
: A Study
一项研究
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引用次数: 0
期刊
Archives of clinical and medical case reports
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