MJ Vivancos-Gallego, Mónica García Cosío, Inmaculada Espinosa-Monroy
A 28-year-old male was referred by his primary care physician for workup of possible oral candidiasis. He had been diagnosed with asymptomatic HIV-infection 18 months earlier and had undetectable viral load under antiretroviral treatment. The patient reported a history of multiple unprotected sexual encounters over the preceding 3 months. Physical examination showed painless and confluent whitish mucous patches (about 2 cm long) with erythematous border on the left soft palate which did not scrape off with a tongue depressor (Panel A). A biopsy specimen from the damaged mucosa was obtained and revealed hyperplasia of the epithelium and a dense inflammatory infiltrate in the corion, composed mainly by plasma cells (Panel B and C). Immunohistochemistry highlights numerous treponemal spirochetes, brown chromogen (Panel D and E). Treponemal tests (EIA and TPPA) were reactive and Rapid Plasma Reagin test (RPR) was positive (titer, 1:32). A diagnosis of syphilis was made. The patient was initially treated with intramuscular penicillin G benzathine. At 3-month follow-up he had complete resolution of palate lesion.
{"title":"Syphilitic Leukoplakia","authors":"MJ Vivancos-Gallego, Mónica García Cosío, Inmaculada Espinosa-Monroy","doi":"10.26502/acmcr.96550570","DOIUrl":"https://doi.org/10.26502/acmcr.96550570","url":null,"abstract":"A 28-year-old male was referred by his primary care physician for workup of possible oral candidiasis. He had been diagnosed with asymptomatic HIV-infection 18 months earlier and had undetectable viral load under antiretroviral treatment. The patient reported a history of multiple unprotected sexual encounters over the preceding 3 months. Physical examination showed painless and confluent whitish mucous patches (about 2 cm long) with erythematous border on the left soft palate which did not scrape off with a tongue depressor (Panel A). A biopsy specimen from the damaged mucosa was obtained and revealed hyperplasia of the epithelium and a dense inflammatory infiltrate in the corion, composed mainly by plasma cells (Panel B and C). Immunohistochemistry highlights numerous treponemal spirochetes, brown chromogen (Panel D and E). Treponemal tests (EIA and TPPA) were reactive and Rapid Plasma Reagin test (RPR) was positive (titer, 1:32). A diagnosis of syphilis was made. The patient was initially treated with intramuscular penicillin G benzathine. At 3-month follow-up he had complete resolution of palate lesion.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Smolle, Judith C. Geißler, S. Nischwitz, H. Luze, L. Kamolz
Elderly burn patients are at increased risk for wound healing complications, as their injuries are more likely to become deep and wound healing is impaired. Furthermore, higher age is a known risk factor for burn wound infection. New biologic matrices are promising tools in the armamentarium of wound care specialists in application of hard-to-heal wounds. We present a case of an elderly burn patient with chronic wounds that were ultimately healed using marine omega3 wound matrix for wound conditioning and meek micrografting for closure. As the patient general health status did not allow surgery under general anaesthesia, skin grafting was performed bed-side under topical anaesthesia.
{"title":"Healing of a Chronic Wound after Extensive Burn Injury in An Elderly Patient Using Marine Omega3 Wound Matrix and Split-Thickness Skin Micro-Grafts: A Case Report","authors":"C. Smolle, Judith C. Geißler, S. Nischwitz, H. Luze, L. Kamolz","doi":"10.26502/acmcr.96550616","DOIUrl":"https://doi.org/10.26502/acmcr.96550616","url":null,"abstract":"Elderly burn patients are at increased risk for wound healing complications, as their injuries are more likely to become deep and wound healing is impaired. Furthermore, higher age is a known risk factor for burn wound infection. New biologic matrices are promising tools in the armamentarium of wound care specialists in application of hard-to-heal wounds. We present a case of an elderly burn patient with chronic wounds that were ultimately healed using marine omega3 wound matrix for wound conditioning and meek micrografting for closure. As the patient general health status did not allow surgery under general anaesthesia, skin grafting was performed bed-side under topical anaesthesia.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Berarducci, M. Colasante, Mariateresa Laborante, A. Laborante
Purpose: To report a rare case of postoperative Acanthamoeba endophthalmites after uncomplicated cataract surgery in an otherwise healthy patient. Case Description: A patient with preexisting glaucoma and CNV in both eyes underwent uneventful cataract surgery (PHACO + IOL + intracamerular cefuroxima) in his right eye. Nine days after surgery, patient presented in eye casualty complaining drop in vision, eye pain and violent diarrhoea. Pars plana vitrectomy was performed and Acanthamoeba protozoa was isolated. Empirical therapy including intravenous voriconazole 2, 5 mg twice a day, a single shot of intravitreal voriconazole 1% in 0,1 ml and topical chlorhexidine 0,02% topical was started immediately. Conclusions: sixteen days from the initial symptoms a complete resolution of the endophthalmites was reported as well as an improvement in the visual acuity. Physicians should be aware of Acanthamoeba infection as a cause of eye infection in any patient, not just contact lens wearers; intravitreal and systemic administration of voriconazole can be successfully used to treat Acanthamoeba endophthalmitis
{"title":"A Rare Case of Postoperative Acanthamoeba Endophthalmites after Uneventful Cataract Surgery","authors":"A. Berarducci, M. Colasante, Mariateresa Laborante, A. Laborante","doi":"10.26502/acmcr.96550621","DOIUrl":"https://doi.org/10.26502/acmcr.96550621","url":null,"abstract":"Purpose: To report a rare case of postoperative Acanthamoeba endophthalmites after uncomplicated cataract surgery in an otherwise healthy patient. Case Description: A patient with preexisting glaucoma and CNV in both eyes underwent uneventful cataract surgery (PHACO + IOL + intracamerular cefuroxima) in his right eye. Nine days after surgery, patient presented in eye casualty complaining drop in vision, eye pain and violent diarrhoea. Pars plana vitrectomy was performed and Acanthamoeba protozoa was isolated. Empirical therapy including intravenous voriconazole 2, 5 mg twice a day, a single shot of intravitreal voriconazole 1% in 0,1 ml and topical chlorhexidine 0,02% topical was started immediately. Conclusions: sixteen days from the initial symptoms a complete resolution of the endophthalmites was reported as well as an improvement in the visual acuity. Physicians should be aware of Acanthamoeba infection as a cause of eye infection in any patient, not just contact lens wearers; intravitreal and systemic administration of voriconazole can be successfully used to treat Acanthamoeba endophthalmitis","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Lena, F. Tamburella, Matteo x Matteo Lo Russo, Marta Mascanzoni, G. Scivoletto
Hyperhidrosis is a well-documented consequence of spinal cord injuries (SCI). It affects about 25% of the subjects with SCI representing a social problem, a cause of discomfort and a risk for skin breakdown. Here we present two cases of young subjects with a complete spinal cord lesion at thoracic level, who complained of abnormal sweating. In both patients other possible causes of hyperhidrosis were ruled out. Both subjects were put on pharmacological therapy with oral oxybutynin with immediate relief of the sweating. Although oxybutynin is a very well-known drug in the field of SCI and in the field of idiopathic hyperhidrosis, this is the first time that oxybutynin efficacy in abnormal sweating after SCI has been demonstrated.
{"title":"Hyperhidrosis in Two Patients with Spinal Cord Injury Treated with Oxybutynin: Case Reports and Review of the Literature","authors":"E. Lena, F. Tamburella, Matteo x Matteo Lo Russo, Marta Mascanzoni, G. Scivoletto","doi":"10.26502/acmcr.96550628","DOIUrl":"https://doi.org/10.26502/acmcr.96550628","url":null,"abstract":"Hyperhidrosis is a well-documented consequence of spinal cord injuries (SCI). It affects about 25% of the subjects with SCI representing a social problem, a cause of discomfort and a risk for skin breakdown. Here we present two cases of young subjects with a complete spinal cord lesion at thoracic level, who complained of abnormal sweating. In both patients other possible causes of hyperhidrosis were ruled out. Both subjects were put on pharmacological therapy with oral oxybutynin with immediate relief of the sweating. Although oxybutynin is a very well-known drug in the field of SCI and in the field of idiopathic hyperhidrosis, this is the first time that oxybutynin efficacy in abnormal sweating after SCI has been demonstrated.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjib K. Das, D. Dash, P. Panda, Sandhya Sadana, Reddy M Ravi Kumar, Venkatesh Hari K, D. Kanchibhotla
The Efficacy
的功效
{"title":"The Efficacy of a Plant Based Formulation in the Symptomatic Management of Mild COVID-19 Cases: A Double Blind, Randomized Controlled Trial","authors":"Sanjib K. Das, D. Dash, P. Panda, Sandhya Sadana, Reddy M Ravi Kumar, Venkatesh Hari K, D. Kanchibhotla","doi":"10.26502/acmcr.96550565","DOIUrl":"https://doi.org/10.26502/acmcr.96550565","url":null,"abstract":"The Efficacy","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rickettsia with Atypical Presentation in Rural Population","authors":"Vaishnavi Gurumurthy, Gauri Jain","doi":"10.26502/acmcr.96550567","DOIUrl":"https://doi.org/10.26502/acmcr.96550567","url":null,"abstract":",","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Marinello, Nicolò Presa, Gianluca Cuva, M. Mazzitelli, M. Trevenzoli, L. Sasset, C. Mescoli, F. Nalesso, A. Cattelan
SARS-CoV-2 has tropism and replicates not only in the respiratory tract but also in extrapulmonary organs, such as heart, kidney, and liver. Clinical reports indicate that kidney involvement is frequent and ranges from mild proteinuria to an advanced acute kidney injury (AKI). Similarly, abnormal liver function parameters are commonly found in patients with SARS-CoV-2 infection. We describe a recent and unique case of acute renal failure and hepatocellular injury occurring in the course of a mild SARS-CoV-2 infection. A 37-year-old woman presented at ER with a 5-day history of general asthenia, fever, vomiting, and decreased urine output. She reported a positive SARS-CoV-2 antigen test performed 4 days earlier and no other comorbidities. Initial laboratory findings revealed severe renal impairment (sCr 4.57 mg/dl), non-responsive to intravenous diuretic therapy, with a need to start renal replacement therapy (RRT). She presented also with concomitant liver injury (AST/ALT 875/1349 U/L) for which a liver’s biopsy was performed, finding a morphological aspect suggestive of COVID-related microvascular damage. Further hematochemical and microbiological exams were performed to exclude infectious, metabolic, neoplastic, toxic, and autoimmune diseases, confirming the diagnosis of acute renal failure and hepatocellular injury triggered by SARS-COV-2 infection. Liver and kidney function gradually improved and RRT was stopped after three consecutive sessions. Follow-up showed complete recovery of liver and kidney function twenty-eight days after the onset of symptoms. The case illustrates the complex pathophysiology of COVID-19 that frequently may severely involve extrapulmonary organs, without giving respiratory symptoms, like in this patient.
{"title":"A Unique Case of Acute Renal Failure and Hepatocellular Injury Occurring in the Course of a Mild SARS-CoV-2 Infection","authors":"S. Marinello, Nicolò Presa, Gianluca Cuva, M. Mazzitelli, M. Trevenzoli, L. Sasset, C. Mescoli, F. Nalesso, A. Cattelan","doi":"10.26502/acmcr.96550623","DOIUrl":"https://doi.org/10.26502/acmcr.96550623","url":null,"abstract":"SARS-CoV-2 has tropism and replicates not only in the respiratory tract but also in extrapulmonary organs, such as heart, kidney, and liver. Clinical reports indicate that kidney involvement is frequent and ranges from mild proteinuria to an advanced acute kidney injury (AKI). Similarly, abnormal liver function parameters are commonly found in patients with SARS-CoV-2 infection. We describe a recent and unique case of acute renal failure and hepatocellular injury occurring in the course of a mild SARS-CoV-2 infection. A 37-year-old woman presented at ER with a 5-day history of general asthenia, fever, vomiting, and decreased urine output. She reported a positive SARS-CoV-2 antigen test performed 4 days earlier and no other comorbidities. Initial laboratory findings revealed severe renal impairment (sCr 4.57 mg/dl), non-responsive to intravenous diuretic therapy, with a need to start renal replacement therapy (RRT). She presented also with concomitant liver injury (AST/ALT 875/1349 U/L) for which a liver’s biopsy was performed, finding a morphological aspect suggestive of COVID-related microvascular damage. Further hematochemical and microbiological exams were performed to exclude infectious, metabolic, neoplastic, toxic, and autoimmune diseases, confirming the diagnosis of acute renal failure and hepatocellular injury triggered by SARS-COV-2 infection. Liver and kidney function gradually improved and RRT was stopped after three consecutive sessions. Follow-up showed complete recovery of liver and kidney function twenty-eight days after the onset of symptoms. The case illustrates the complex pathophysiology of COVID-19 that frequently may severely involve extrapulmonary organs, without giving respiratory symptoms, like in this patient.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raquel Madroñero-Mariscal, Natalia Palmero-Valdez, E. González-Parra
multiple
多个
{"title":"Design of a Challenging Prosthetic Fitting Process and Rehabilitation Training Program to Achieve Functionality in a Complex Quadruple Amputee","authors":"Raquel Madroñero-Mariscal, Natalia Palmero-Valdez, E. González-Parra","doi":"10.26502/acmcr.96550571","DOIUrl":"https://doi.org/10.26502/acmcr.96550571","url":null,"abstract":"multiple","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mourad Halfaoui, Fahad Aurif, Abdullah Salman Dalol, Murad Alahmad, Fathimathul Zumara Anwar, Tamer ElBakry
,
，
{"title":"Gall Bladder Duplication: An Interesting Report of Laparoscopic Cholecystectomy performed on Two Cases of Gall Bladder Duplication over a Period of One Week","authors":"Mourad Halfaoui, Fahad Aurif, Abdullah Salman Dalol, Murad Alahmad, Fathimathul Zumara Anwar, Tamer ElBakry","doi":"10.26502/acmcr.96550588","DOIUrl":"https://doi.org/10.26502/acmcr.96550588","url":null,"abstract":",","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01Epub Date: 2023-05-19DOI: 10.26502/acmcr.96550602
Orwa Aboud
{"title":"On Family History.","authors":"Orwa Aboud","doi":"10.26502/acmcr.96550602","DOIUrl":"10.26502/acmcr.96550602","url":null,"abstract":"","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":"210-211"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11351169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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