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Pulmonary Vein Stenosis in an Infant with Bronchopulmonary Dysplasia and Partial Anomalous Pulmonary Venous Circulation: Is This Double Trouble? 支气管肺发育不良和部分肺静脉循环异常的婴儿肺静脉狭窄:这是双重麻烦吗?
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550599
R. Lalitha, K. Norozi, S. Bhattacharya
Pulmonary vein stenosis (PVS) in preterm infants is a rare emerging complication that is associated with bronchopulmonary dysplasia (BPD) which has an unpredictable outcome. Though PVS can be associated with congenital heart defects, its concurrent occurrence in a preterm infant with partial anomalous pulmonary venous return (PAPVR) and severe BPD has not been documented yet. This case shows the potential progressive nature of PVS that might have been aggravated by the presence of two disease condition associated with it and the need for heighted vigilance when an unusual clinical trajectory is demonstrated in a high-risk preterm infant.
早产儿肺静脉狭窄(PVS)是一种罕见的与支气管肺发育不良(BPD)相关的并发症,其预后难以预测。虽然PVS可能与先天性心脏缺陷有关,但其同时发生在部分肺静脉回流异常(PAPVR)和严重BPD的早产儿中尚未见文献记载。本病例显示了PVS的潜在进行性,可能因两种相关疾病的存在而加重,当高危早产儿出现不寻常的临床轨迹时,需要高度警惕。
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引用次数: 0
A Case of Post-Myocardial Infarction Ventricular Septal Rupture and Intramyocardial Dissection 心肌梗死后室间隔破裂并发心内夹层1例
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550605
Jessica Y C Huang, Michael Bourne, B. Rosenfeld, Federico E. Mordini, Christian D. Nagy, Andrew Chen
Ventricular septal rupture (VSR), albeit rare, is a deadly consequence of ST elevation myocardial infarction (STEMI). Our patient described here presented with both post-infarction VSR and intramyocardial dissection (IMD) of the right ventricle (RV), a subtype of left ventricular free wall rupture (LVFWR). This case highlights the importance of prompt diagnosis of these post-myocardial infarction (MI) complications and the current limitations of surgical and percutaneous repair.
室间隔破裂(VSR)虽然罕见,但却是ST段抬高型心肌梗死(STEMI)的致命后果。本例患者表现为梗死后VSR和右心室(RV)心肌内剥离(IMD),这是左心室游离壁破裂(LVFWR)的一种亚型。这个病例强调了及时诊断这些心肌梗死后(MI)并发症的重要性,以及目前手术和经皮修复的局限性。
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引用次数: 0
Seroprevalence of Hepatitis B Virus Infection and Associated Factors among Pregnant Women Attending Antenatal Care centers in Djbouti City, Republic of Djibouti 吉布提共和国吉布提市产前保健中心孕妇乙型肝炎病毒感染的血清阳性率及相关因素
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550619
Sahal Darar Dirir,, A. Ahouidi, Mohamed Osman Miguil
of Clinical
的临床
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引用次数: 0
Decrease Treatment Burden following the Application of ADCES7 and WHOICOPE in a Diabetic Frail Elderly Lady with Multimorbidity 应用ADCES7和WHOICOPE减轻多病糖尿病体弱老年妇女的治疗负担
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550574
T. Chiu, Hui-Chun Hsu, Yau-Jiunn Lee, Der-Wei Hwu
We are living in a world of aging, and the elder population is increasing rapidly. According to the World Health Organization (WHO), the number of people aged 60 or older is about 1 billion in 2019. The numbers are expected to rise to 1.4 billion by 2030 and 2.1 billion by 2050 [1]. Elderlies are frail and they are prone to many diseases, including psychological disorders. Diabetes is also a global problem, and its prevalence increases after middle age [2]. To help clinical health providers to get better pictures of the frail diabetic elderly subjects holistically, many programs or models have been developed. One of the most used assessment and management tools is the integrated care for older people (ICOPE) guideline developed by the WHO [3]. ICOPE was set with person-centered goals, screening for loss in a range of domains of intrinsic capacity and assessing health and social care needs to develop a personalized care plan. The Association of Diabetes Care & Education Specialists 7 Self-Care Behaviors (ADCES7 Self-Care Behaviors®) is also a person-centered approach to diabetes by acknowledging the whole person in the context of their life and relationships which form the framework for diabetes care to deal with people with diabetes [4]. By using the ICOPE and ADCES 7 Self-Care Behaviors®, we were able to evaluate the patient rapidly and further help manages their problems. Here, we present a frail diabetic elderly subject with multimorbidity who had recent medical deterioration. This case is also a good demonstration of holistic care to minimize the disease and treatment burden in a primary care setting.
我们生活在一个老龄化的世界,老年人口正在迅速增加。根据世界卫生组织(世卫组织)的数据,2019年60岁及以上人口的数量约为10亿。预计到2030年,这一数字将增至14亿,到2050年将增至21亿。老年人身体虚弱,容易患许多疾病,包括心理障碍。糖尿病也是一个全球性的问题,其患病率在中年以后上升。为了帮助临床健康提供者更好地全面了解虚弱的糖尿病老年受试者,已经开发了许多程序或模型。最常用的评估和管理工具之一是世卫组织委员会制定的老年人综合护理指南(ICOPE)。ICOPE的设定是以人为中心的目标,筛查一系列内在能力领域的丧失,评估保健和社会护理需求,以制定个性化护理计划。糖尿病护理与教育专家协会7自我护理行为(ADCES7自我护理行为®)也是一种以人为本的糖尿病治疗方法,它承认整个人在他们的生活和关系的背景下,形成了糖尿病护理框架,以应对糖尿病患者。通过使用ICOPE和ADCES 7自我护理行为®,我们能够快速评估患者并进一步帮助管理他们的问题。在这里,我们提出了一个身体虚弱的老年糖尿病患者,患有多种疾病,最近病情恶化。该病例也很好地证明了在初级保健环境中采用整体护理以尽量减少疾病和治疗负担。
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引用次数: 0
Neonate with Severe Tricuspid Regurgitation and Flail Anterior Leaflet of the Tricuspid Valve 新生儿有严重的三尖瓣反流和连枷状三尖瓣前部小叶
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550634
Matthew F Pizzuto, Chris S Iskander, J. Ryan Shea
Flail anterior tricuspid valve leaflet is a rare source of primary tricuspid regurgitation. It can be challenging to manage medically in neonates and often requires surgical repair. This case describes the use of medical management of a patient with flail tricuspid valve leaflet with severe tricuspid regurgitation to avoid neonatal cardiac surgery
连枷状前三尖瓣小叶是一种罕见的原发性三尖瓣反流的来源。对新生儿进行医学治疗可能具有挑战性,通常需要手术修复。本病例描述了使用医疗管理的患者连枷状三尖瓣瓣小叶严重三尖瓣反流,以避免新生儿心脏手术
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引用次数: 0
Use of Next-Generation Sequencing Techniques in the Accurate Diagnosis of Neural Crest Cell-Derived Tumors 新一代测序技术在神经嵴细胞源性肿瘤准确诊断中的应用
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550633
Juan F Rodríguez Moreno, Mario Prieto, Sara Palacios Zambrano, Miriam Dorta, Elena Sevillano, Paloma Navarro, Isabel Salas Villar, Antonio Cubillo, Jesús García Donas
The increasing adoption of next-generation sequencing (NGS) techniques in daily practice has led to the incorporation of molecular information in the diagnosis and management of cancer patients. Taking advantage of these new tools could clearly impact the outcome of cases we present the case of a 39-year-old woman who attended the emergency department for fever and dysphagia. Computed axial tomography revealed a solid lesion in the subcarinal region. Histologically, the mass showed a tumor with proliferation of spindle cells containing elongated, hyperchromatic nuclei and brownish pigment in the cytoplasm. On immunohistochemical staining, the cells were positive for S-100, SOX10, P16 and HMB 45 and negative for CKAE1/AE3 and actin. Consequently, given the location and clinical findings, the mass was tentatively diagnosed as locally advanced esophageal mucosal melanoma. Further genetic testing with an NGS panel identified EWSR1-ATF1 fusion, resulting from translocation t(12;22)(q13-14;Q12). These new data were combined with all the available information, and the patient was diagnosed with clear cell sarcoma, which was treated with radical-intent radiotherapy. The use of NGS platforms to determine the genetic profile of the tumor facilitated the correct diagnosis of this rare neoplasm with melanocytic differentiation, an entity that presents a broad differential diagnosis with other neural crest cell-derived tumors. As a result, the patient received proper treatment based in precision medicine in line with the new molecular findings described.
在日常实践中越来越多地采用新一代测序(NGS)技术,导致将分子信息纳入癌症患者的诊断和管理。利用这些新工具可以明显地影响病例的结果,我们提出了一个39岁的女性病例,她因发烧和吞咽困难而到急诊室就诊。计算机轴位断层扫描显示隆突下区域有实性病变。组织学上,肿块呈梭形细胞增生,细胞核长而深染,细胞质中有褐色色素。免疫组化染色显示细胞S-100、SOX10、P16、hmb45阳性,CKAE1/AE3、actin阴性。因此,鉴于位置和临床表现,肿块暂定诊断为局部晚期食管黏膜黑色素瘤。进一步的NGS基因检测发现EWSR1-ATF1融合是由易位t引起的(12;22)(q13-14;Q12)。这些新数据与所有可用信息相结合,患者被诊断为透明细胞肉瘤,并接受根治性放射治疗。使用NGS平台确定肿瘤的遗传谱有助于正确诊断这种罕见的黑色素细胞分化肿瘤,这一实体与其他神经嵴细胞源性肿瘤具有广泛的鉴别诊断。因此,患者接受了基于精确医学的适当治疗,与所描述的新分子发现一致。
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引用次数: 0
Teaching NeuroImages: Gerstmann Syndrome in a Pediatric Patient with a Dominant Parietal Pleomorphic Xanthroastrocytoma 教学神经影像:小儿显性顶叶多形性人类星形细胞瘤患者的Gerstmann综合征
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550610
Chattip Prueksapraopong, Angeline Zhou, B. Yu, Carrie Ip, Audrey Nath
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引用次数: 0
Evidence Based Physical Medicine in Internal Medicine 内科循证物理医学
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550612
Zouna Frank, Ngomba Maryl
Introduction: The teaching of physical examination is based on medical textbooks. In the era of technology and evidence-based medicine, clinician should be able to perform and accurate physical examination. In this review, we propose a new way of doing physical examination with accuracy. Methods: We searched PubMed from 1980 to 2022. We included studies that compared physical examination with imaging, electrophysiological studies and intraoperative findings. Results: We have identified a bare minimum for head to toes examination. The content is vital signs, eyes inspection, mouth inspection, lymph nodes palpation, thyroid palpation, lungs examination (inspection, percussion and auscultation), heart examination (inspection and auscultation), abdomen (inspection and palpation), vascular examination (dorsalis pedis and posterior tibial artery palpation), neurologic examination (eyes movement, facial strength, tongue, thumb rolling test, ankle reflex, gait). Conclusions: Physical examination of human major systems can be done within 10 minutes with accuracy.
简介:体检教学以医学教材为基础。在科技和循证医学的时代,临床医生应该能够进行准确的身体检查。在此综述中,我们提出了一种新的准确体检方法。方法:检索PubMed 1980 - 2022年。我们纳入了将体格检查与影像学、电生理检查和术中发现进行比较的研究。结果:我们已经确定了从头到脚趾检查的最低限度。内容为生命体征、眼部检查、口腔检查、淋巴结触诊、甲状腺触诊、肺部检查(检查、叩诊和听诊)、心脏检查(检查和听诊)、腹部检查和触诊、血管检查(足背和胫后动脉触诊)、神经检查(眼动、面部力量、舌、拇指滚动试验、踝关节反射、步态)。结论:人体主要系统的体检可在10分钟内准确完成。
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引用次数: 0
Endocarditis at Prior Venous Cannulation Site after Sternal Wound Infection: Case Report 胸骨伤口感染后静脉插管部位心内膜炎1例
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550617
Jared Cappelli, Amber Edwards
Endocarditis originating from a prior venous cannulation site is undescribed in the current literature. Infections of the heart pose significant morbidity and mortality to patients, therefore prompt recognition, diagnosis, and treatment are critical. Our patient underwent coronary artery bypass grafting (CABG) and developed a postoperative sternal wound infection with methicillin resistant staphylococcus aureus (MRSA). After failing nonoperative management, redo-sternotomy was performed with atrial wall debridement and patch repair. During this procedure, two unexpected small discrete abscess pockets of the right atrial epicardium were discovered. One of the abscess pockets fistulized into the right atrium and was noted to be at his prior venous cannulation site for cardiopulmonary bypass as evidenced by neighboring prolene suture. The patient had an uneventful recovery and was discharged home on postoperative day 7. Transthoracic echo was obtained 6 weeks after his second operation and did not show any recurrence of endocarditis. We present a unique case of persistent cardiac infection with a complicated course and management strategy.
起源于先前静脉插管部位的心内膜炎在当前文献中有描述。心脏感染对患者造成严重的发病率和死亡率,因此及时识别、诊断和治疗至关重要。我们的病人接受了冠状动脉旁路移植术(CABG),术后胸骨伤口感染了耐甲氧西林金黄色葡萄球菌(MRSA)。非手术治疗失败后,行胸骨切口、心房壁清创和补片修补术。在此过程中,在右心房心外膜发现了两个意想不到的小的离散脓肿袋。其中一个脓肿袋进入右心房,并在他之前进行体外循环静脉插管的位置被注意到,邻近的prolene缝合线证明了这一点。患者顺利康复,术后第7天出院回家。第二次手术后6周行经胸超声检查,未见心内膜炎复发。我们提出一个独特的病例持续心脏感染与复杂的过程和管理策略。
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引用次数: 0
Early Femoral Failure in Two Patients Undergoing Downsizing of the Femoral Component During High-Flexion Total Knee Arthroplasty 2例高屈曲全膝关节置换术中股骨假体缩小的早期股骨功能衰竭
Pub Date : 2023-01-01 DOI: 10.26502/acmcr.96550593
J. Baek, S. Lee, Seung Hyun Hwang, Taehyeon Kim, H. Ahn, Chang Hyun Nam
Introduction and Importance: High-flexion prostheses can be associated with a greater risk of early aseptic loosening of the femoral component than standard prosthesis. Case presentation: We describe two patients in whom high-flexion total knee arthroplasty (TKA) was performed using the anterior referencing (AR) method that resulted in early aseptic loosening of the downsized femoral component. Conclusion: Excessive bone resection of the posterior femoral condyle by additional downsizing of the femoral component during high-flexion TKA using the AR method could lead to early failure of the femoral component.
介绍和重要性:与标准假体相比,高屈曲假体早期无菌性股骨假体松动的风险更大。病例介绍:我们描述了两例患者,他们使用前参考(AR)方法进行高屈曲全膝关节置换术(TKA),导致早期无菌性松动缩小的股骨组成部分。结论:在采用AR方法进行高屈曲TKA时,通过进一步缩小股骨假体来切除股骨后髁可能导致股骨假体早期失效。
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引用次数: 0
期刊
Archives of clinical and medical case reports
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