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Lingual Mucosal Lesions for Starting the Secondary Stage of Syphilis: A Case Report 舌黏膜病变开始二期梅毒:1例报告
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550490
Min Zhao
Background: Recent years syphilis has the increased case rates among men who have sex with men and remains a continuing public health challenge globally. Owing to its varied manifestations of oral mucosa in syphilis that can mimic other infections, it should be distinguished from oral ulcer, candidiasis, oral lichen planus, oral leukoplakia and so on. Case Presentation: This case report describes the patient with white plaques of the lingual mucosa for the secondary stage of syphilis in a 23-year-old male. It was a rare case that oral mucosal lesions as the only manifestations of secondary syphilis. And the differential diagnosis, treatment, follow-up visits and attentions were discussed. Conclusions: The clinicians need to distinguish the oral clinical presentations of syphilis from other oral diseases for suspected syphilis patients and to achieve early diagnosis and treatment. As well do a good job in relevant self-protection, instrument disinfection and management of nosocomial infection.
背景:近年来,梅毒在男男性行为者中的发病率有所上升,仍然是全球公共卫生的一个持续挑战。由于梅毒口腔黏膜表现多样,可模仿其他感染,应与口腔溃疡、念珠菌病、口腔扁平苔藓、口腔白斑等相鉴别。病例介绍:本病例报告描述了一例23岁男性梅毒继发期舌黏膜白色斑块患者。以口腔黏膜病变为继发性梅毒的唯一表现是罕见的。并对鉴别诊断、治疗、随访及注意事项进行了讨论。结论:临床医师对疑似梅毒患者应将其口腔临床表现与其他口腔疾病区分开来,做到早期诊断和早期治疗。做好相关的自我防护、器械消毒和医院感染管理工作。
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引用次数: 0
Transcatheter Closure of a Ragged Post-Myocardial Infarction Ventricular Septal Defect Using an Off-Label ASD Occluder 使用标签外ASD封堵器经导管关闭心肌梗死后不规则室间隔缺损
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550452
C. Quast, S. Afzal, P. Leuders, M. Masyuk, K. Klein, M. Kelm, A. Polzin, T. Zeus
Post-myocardial infarction ventricular septal defect has become a rare event following ST Elevation Myocardial Infarction (STEMI) but is still a life-threatening complication with high mortality. Transcatheter closure of post-myocardial infarction ventricular septal defects has emerged as an alternative therapeutic approach but often requires individual strategies due to complex morphology. We report a case of a 62-year-old man who was admitted to our hospital after STEMI of the inferior wall with pulmonary congestion due to a post-myocardial infarction VSD for interdisciplinary evaluation and therapy. The patient was characterized by estimated high perioperative risk and underwent interventional closure of the VSD according to heart team decision. Because of ragged nature of the VSD closure with a conventional Occlutech VSD occluder was not possible. Therefore, we decided to close the defect using an off-lable device for ASD closure which Arch Clin Med Case Rep 2022; 6 (1): 66-71 DOI: 10.26502/acmcr.96550452 Archives of Clinical and Medical Case Reports 67 was successfully implanted without relevant residual shunt.
心肌梗死后室间隔缺损已成为ST段抬高型心肌梗死(STEMI)后的罕见事件,但仍是危及生命的高死亡率并发症。经导管关闭心肌梗死后室间隔缺损已成为一种替代治疗方法,但由于其复杂的形态学,往往需要个体策略。我们报告一例62岁男性患者,因心肌梗死后室间隔缺损(VSD)致下壁STEMI后肺充血而入院,以进行跨学科评估和治疗。患者的围手术期风险较高,根据心脏团队的决定,接受了室间隔关闭手术。由于VSD闭合的粗糙性,使用传统的Occlutech VSD闭塞器是不可能的。因此,我们决定使用一种可关闭ASD的设备来关闭缺陷,Arch clinmed Case Rep 2022;6 (1): 66-71 DOI: 10.26502/acmcr.96550452临床与医疗病例报告档案67例成功植入,无相关分流残留。
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引用次数: 1
A Case Report on Bronchial Asthma with Myopathy 支气管哮喘伴肌病1例报告
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550453
SM. Shahidul Islam, Rehana Akter Lima
Muscle disease is referred to as myopathy. As a result, the muscles are less efficient than they might be. When muscles don't grow correctly, are injured, or are missing vital components, this might happen. Muscle atrophy is common in patients who have had Bronchial Asthma with Myopathy for a long time. Muscles lose mass and strength as a result of this fading away. We recently treated a patient who was experiencing some of the same issues. We suggested a Brain MRI and total spine screening to the patient which indicated hypoplasticity in the left transverse sinus. An X-Ray of the chest indicated that the left inferior nasal turbinate had expanded. Traditional therapies like acupuncture and massage, as well as modern techniques like multipurpose equipment and physiotherapy, were chosen to treat our patients. Our patient had wonderful success with these strategies. The procedure for the patient’s treatment has been completed. At the end of the 12th day of chest treatment, the patient was completely free of breathlessness. On the 10th day of acupuncture, the patient’s low back discomfort began to improve. At the end of the 20th day of therapy, the patient's headache begins to improve. Moreover, the authors believe that it is the first successful reported case in Bangladesh using these techniques. Arch Clin Med Case Rep 2022; 6 (1): 72-77 DOI: 10.26502/acmcr.96550453 Archives of Clinical and Medical Case Reports 73
肌肉疾病被称为肌病。因此,肌肉的效率比它们可能的要低。当肌肉不能正常生长、受伤或缺少重要成分时,就可能发生这种情况。肌肉萎缩常见于支气管哮喘伴肌病患者。肌肉失去质量和力量的结果是这种消退。我们最近治疗了一个病人,他也有同样的问题。我们建议对发现左横窦可塑性不足的患者进行脑MRI和全脊柱筛查。胸部x光片显示左下鼻甲扩张。我们选择了针灸和按摩等传统疗法,以及多功能设备和物理疗法等现代技术来治疗患者。我们的病人通过这些策略取得了巨大的成功。病人的治疗程序已经完成。胸部治疗第12天结束时,患者完全无呼吸困难。针灸第10天,患者腰背部不适开始改善。治疗第20天结束时,患者头痛开始好转。此外,作者认为,这是孟加拉国第一个使用这些技术成功报告的病例。Arch clinin Med Case Rep 2022;6 (1): 72-77 DOI: 10.26502/acmcr.96550453临床和医疗病例报告档案
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引用次数: 0
Bilateral Approach with Botulinum Toxin Type A Injections in Patients with One-Sided Facial Hyperkinetic Movements 双侧入路注射A型肉毒杆菌毒素治疗单侧面部运动过度
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550462
C. Karapantzou, Joao Pedro Vale, Frank Joachim Haubner, Konstantinos Zagoridis, Konstantinos Agas, Konstantinos Karagogos, Nikoleta Zagoridou, M. Canis
Background: Main subject of our investigation was to clarify, if a bilateral approach with Botulinum toxin type A injections is more efficient from cosmetic and functional aspect, compared to unilateral injections, in patients with one-sided facial hyperkinetic movements, like synkinesis and hemi facial spasm. Methods: Our patient cohort included 30 patients suffering from unilateral hyperkinetic facial contractions. We performed a total of 60 injections, 30 of them only on the Arch Clin Med Case Rep 2022; 6 (2): 149-172 DOI: 10.26502/acmcr.96550462 Archives of Clinical and Medical Case Reports 150 affected side and 30 on both facial sides. All participants underwent 2 botulinum toxin sessions, with a 4 months period lying between the injections. Our statistical analysis was divided into 4 hypothesis testing sub-groups, based on the results of the subjective satisfaction rates our patients delivered 2 months and 6 months after the initial botulinum toxin session. Furthermore 2 doctors evaluated the results based on pre-and after photographs on a Quartile Grading Scale for objective evaluation for the same time periods. Each one of the observers received one patient group, either with bilateral or with ipsilateral treatments, without knowing which group they received. Results: Summarizing the statistical results we analyzed from both sources (patients and doc-tors-observers), we found statistically significant differences in satisfaction rate between the two groups (p=.004) and a better objective evaluation on patients who underwent combined treatments. Conclusions: Our work confirmed the initial assumption that patients with facial asymmetry of different etiology benefit from a bilateral therapeutic approach with botulinum toxin injections, instead of one-sided injections into the hyperkinetic or dyskinesia facial side.
背景:我们研究的主要目的是阐明,对于单侧面部运动过度的患者,如联动性和半面肌痉挛,双侧注射a型肉毒杆菌毒素是否比单侧注射更有效,从美容和功能方面。方法:我们的患者队列包括30例患有单侧面部过度运动性收缩的患者。我们共进行了60次注射,其中30次仅针对Arch clinm病例Rep 2022;6 (2): 149-172 DOI: 10.26502/acmcr.96550462临床与医学病例档案报告患侧150例,双侧30例。所有参与者都进行了两次肉毒杆菌毒素注射,注射间隔为4个月。根据患者在首次肉毒杆菌治疗后2个月和6个月的主观满意度,我们将统计分析分为4个假设检验亚组。此外,2名医生根据同一时间段的客观评价四分位分级量表对前后照片进行了评估。每个观察者接受一个病人组,要么接受双侧治疗,要么接受同侧治疗,不知道他们接受的是哪一组。结果:综合两组(患者和医生-观察者)的统计结果,我们发现两组患者的满意率差异有统计学意义(p= 0.004),对联合治疗的患者有更好的客观评价。结论:我们的工作证实了最初的假设,即不同病因的面部不对称患者受益于双侧注射肉毒杆菌毒素的治疗方法,而不是单方面注射到多动或运动障碍的面部一侧。
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引用次数: 0
Diagnosis and Treatment of an Infected Supraorbital Ethmoid Cell Cyst 一例感染性眶上筛细胞囊肿的诊断与治疗
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550467
K. Koda, K. Yasuhara
1. Case Report A 79-year-old woman with no significant medical history visited an emergency room with a complaint of diplopia. Ocular motility disorder was noted, and a central lesion was suspected. Contrast-enhanced computed tomography (CT) revealed a cystic lesion, and cyst infection was suspected based on the rim enhancement. Coronal images (Figure 1) suggested a frontal sinus cyst, but horizontal (Figure 2) and sagittal (Figure 3) sections revealed a Supraorbital Ethmoid-Cell (SOEC) cyst extending into the orbit. Diplopia disappeared immediately after endoscopic surgery for cyst enucleation. Anatomically, SOECs are associated with the anterior ethmoidal artery (AEA), which runs within or in continuity with the posterior border of the SOEC opening [1] (Figure 4). Therefore, in endoscopic surgery, the risk of AEA damage increases with a posterior approach, and an approach from the front is recommended. If an axillary flap [2] is not created and the nasal ridge is not sufficiently excised, it is difficult to operate using an endoscope.
1. 病例报告一名79岁无明显病史的妇女以复视就诊于急诊室。注意到眼球运动障碍,并怀疑中心病变。计算机断层扫描(CT)显示一个囊性病变,根据边缘增强怀疑囊肿感染。冠状面(图1)显示额窦囊肿,但水平(图2)和矢状面(图3)显示眼眶上筛细胞(SOEC)囊肿延伸至眼眶。内窥镜囊肿摘除术后复视立即消失。在解剖学上,SOEC与筛前动脉(AEA)相关,该动脉在SOEC开口bb0的后边界内或与之连续(图4)。因此,在内镜手术中,AEA损伤的风险随着后入路的增加而增加,建议从前方入路。如果没有创建腋窝皮瓣,鼻脊没有充分切除,则难以使用内窥镜进行手术。
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引用次数: 0
Peracute Onset Pediatric Myelin Oligodendrocyte Glycoprotein Antibody Associated Focal Cortical Encephalitis: A Case Report 小儿髓磷脂少突胶质细胞糖蛋白抗体相关局灶性皮质脑炎1例报告
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550522
Johanna Sophie Pohl, F. Leypoldt, Naomi Larsen, A. van Baalen, K. Wandinger, K. Rostásy, H. Muhle
Recently, several case series have described pediatric patients presenting with new onset focal seizures together with relapsing fever and cortical T2/FLAIR hyperintensities in association with myelin oligodendrocyte glycoprotein (MOG) antibodies, in adults known as unilateral cortical fluid-attenuated inversion recovery (FLAIR) hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES). A previously healthy 12-year-old girl first arrived to the emergency department with stroke-like symptoms, including hemiparesis, facial palsy, and severe headache. Heparin therapy was initiated; seizures were successfully treated with valproate. Due to persistent cortical edema in brain magnetic resonance imaging (MRI), anti-inflammatory treatment with high dose dexamethasone was initiated and led to prompt recovery. One month later, the patient displayed fever and headache of unknown origin. Brain MRI showed cortical FLAIR hyperintensities and leptomeningeal contrast enhancement. Cerebrospinal fluid (CSF) analyses including autoimmune diagnostics revealed a lymphocytic pleocytosis, elevated protein, and positive oligoclonal bands. MOG antibodies in serum and CSF were positive. Intravenous methylprednisolone (IVMP), followed by oral tapering, led to complete recovery, yet one relapse occurred and intravenous immunoglobulins (IVIG) were added, given monthly to date. Our patient remained relapse-free for eight months when moderate but persisting headache and paraesthesia reoccurred. Methylprednisolone therapy was given, but outstanding MOG antibodies in serum and CSF were negative. Therefore, maintenance therapy was not extended. Single focal seizures led to adjustment of antiseizure medication. In summary, this is the first case report of a pediatric patient with MOG encephalitis, first presenting stroke-like symptoms, reminiscent of the newly described FLAMES syndrome.
最近,几个病例系列描述了儿童患者出现新发局灶性癫痫并伴有回复热和髓鞘少突胶质细胞糖蛋白(MOG)抗体相关的皮质T2/FLAIR高信号,在成人中称为抗MOG相关脑炎发作(火焰)的单侧皮质液体减毒反转恢复(FLAIR)高信号病变。一名原本健康的12岁女孩首次来到急诊科时出现中风样症状,包括偏瘫、面瘫和严重头痛。开始肝素治疗;癫痫发作用丙戊酸盐成功治疗。由于脑磁共振成像(MRI)显示持续的皮质水肿,开始使用大剂量地塞米松进行抗炎治疗并迅速恢复。1个月后,患者出现不明原因的发热和头痛。脑部MRI显示皮层FLAIR高信号及脑轻脑膜造影增强。脑脊液(CSF)分析包括自身免疫诊断显示淋巴细胞增多,蛋白升高,阳性寡克隆带。血清和脑脊液中MOG抗体阳性。静脉注射甲基强的松龙(IVMP),随后口服减量,导致完全恢复,但有一次复发发生,静脉注射免疫球蛋白(IVIG),每月给予至今。当中度但持续的头痛和感觉异常再次发生时,我们的患者保持了8个月无复发。给予甲基强的松龙治疗,但血清和脑脊液中MOG抗体明显阴性。因此,维持治疗没有延长。单灶性癫痫导致抗癫痫药物的调整。总之,这是首例小儿MOG脑炎患者的病例报告,首先表现为卒中样症状,使人想起新描述的火焰综合征。
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引用次数: 0
CADASIL or MS? Consider “Red Flags” but Avoid a Misdiagnosis: Case Series of a Concomitant Diagnosis CADASIL还是MS?考虑“危险信号”但避免误诊:伴随诊断的病例系列
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550530
Morena Emanuele, Lucchi Matteo, Romano Carmela, Petrucci Simona, Tartaglia Matteo, Morosetti Roberta, Conte Antonella, Buscarinu Maria Chiara, Romano Silvia, Salvetti Marco, Mirabella Massimiliano, Ristori Giovanni
Affiliation: 1Centre for Experimental Neurological Therapies (CENTERS), Department of Neurosciences, Mental Health and Sensory Organs, Sapienza University of Rome, Rome, Italy 2Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Istituto di Neurologia, Università Cattolica del Sacro Cuore, Rome, Italy 3Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy 4Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy 5Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy 6Neuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy
Affiliation:1Centre for实验Neurological Therapies(中心),Department of Neurosciences Mental Health and Sensory Organs罗马智慧大学、罗马、意大利2Fondazione大学综合医院”A .双胞胎“IRCCS、神经病学研究所、圣心天主教大学、罗马、意大利3Department of神经学and Psychiatry Sapienza University of罗马,罗马,意大利4Department of Human Neurosciences,罗马,罗马智慧大学,地中海神经医学研究所,波兹利,意大利神经免疫学股,圣卢西亚,罗马,意大利
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引用次数: 0
Unexpected Elevation of Infection Parameters in a Heart Transplanted Patient with Chronic Kidney Disease: A Case Report 慢性肾脏疾病心脏移植患者感染参数意外升高一例报告
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550558
Kurzhagen Jt, Roeder Ss, M. J
Patients with end-stage kidney disease are under an increased risk for morbidity and mortality due to cardiovascular reasons. Yet, patients might show only atypical symptoms during cardiac events and routinely performed pre-transplant diagnostic measures are discussed controversially. A heart transplanted 50-year-old male with end-stage kidney disease was assessed for kidney transplantation. Myocardial scintigraphy, chest x-ray, pulmonary function test, urological and gastrointestinal assessment showed normal results. A routinely performed blood test revealed elevated procalcitonin, C-reactive protein and leucocytes. Measured vital parameters and physical examination revealed no pathologies. Coughing, shortness of breath or chest pain were denied. CT-scan showed no signs of infection but lack of contrast media enhancement in the heart. Myocardial infarction was confirmed in electrocardiogram and transthoracic echocardiogram demonstrated an impaired ejection fraction of 20%. Treatment with anti-platelet medication and anticoagulation was followed by invasive heart catheterization, which revealed no acute stenosis but a dissolved in-stent thrombosis. Since kidney failure was progressing the patient required dialysis treatment. Microbiological analyses of blood and urine samples stayed negative. Chronic kidney disease patients are at increased cardiovascular risk. However, invasiveness of cardiac diagnostics for potential kidney transplant is debated controversially. KDIGO guideline 2020 advises non-invasive screening for coronary artery disease for asymptomatic patients at high risk. However, there is no specific guideline for previously heart transplanted candidates for kidney transplant and patients with high pretest probability benefit from invasive diagnostics. A risk stratification for cardiac complications and pre-kidney transplant evaluation should be executed in clinical practice.
终末期肾病患者由于心血管疾病的原因,发病率和死亡率的风险增加。然而,在心脏事件期间,患者可能仅表现出非典型症状,并且常规进行移植前诊断措施存在争议。一个心脏移植的终末期肾病的50岁男性评估肾移植。心肌显像、胸片、肺功能检查、泌尿及胃肠检查均正常。常规血液检查显示降钙素原、c反应蛋白和白细胞升高。测量生命参数及体格检查未见病理。咳嗽、呼吸急促或胸痛均不存在。ct扫描未见感染迹象,但心脏缺乏造影剂增强。心电图证实心肌梗死,经胸超声心动图显示射血分数下降20%。抗血小板药物和抗凝治疗后进行有创心导管插管,无急性狭窄,但溶解的支架内血栓形成。由于肾衰竭的进展,病人需要透析治疗。血液和尿液样本的微生物分析呈阴性。慢性肾病患者心血管疾病风险增加。然而,心脏诊断对潜在肾移植的侵入性存在争议。KDIGO指南2020建议对无症状高危患者进行无创冠状动脉疾病筛查。然而,对于先前接受过心脏移植的肾移植候选人,目前还没有具体的指导方针,而且有高预诊概率的患者可以从侵入性诊断中获益。在临床实践中应对心脏并发症和肾移植前评估进行风险分层。
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引用次数: 0
Lower GI Bleeding and Left Colon Blue Rubber Blebs: Rare Case Report 下消化道出血及左结肠蓝色橡胶泡:罕见病例报告
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550560
Fahad Al-Lhedan, A. Kurdi
A middle-aged male who is known to have acne vulgaris on oral treatment complaining of hematochezia containing blood clots for few weeks. The patient underwent colonoscopy displaying several left colon blue rubber blebs and here we are presenting this rare case.
一名中年男性,已知患有寻常性痤疮,正在口服治疗,他抱怨几周内出现含血凝块的便血。患者接受结肠镜检查显示几个左结肠蓝色橡胶泡,在这里我们呈现这个罕见的病例。
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引用次数: 0
Knowledge, Attitude and Perceptions towards COVID-19 Vaccination among South Indian (Telangana) Population - A Cross Sectional Study 南印度(特伦甘纳邦)人口对COVID-19疫苗接种的知识、态度和看法——一项横断面研究
Pub Date : 2022-01-01 DOI: 10.26502/acmcr.96550485
Srimanth Kumar Barigela, Rajesh Kumar Galimudi, Shivani Kadarla, Durga Neeharika Rani, Pardha P. Reddy, Madhavi Jangala, Sunita G Kumar
Knowledge, Attitude and Perceptions towards COVID-19
对COVID-19的知识、态度和看法
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引用次数: 0
期刊
Archives of clinical and medical case reports
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