Background: Recent years syphilis has the increased case rates among men who have sex with men and remains a continuing public health challenge globally. Owing to its varied manifestations of oral mucosa in syphilis that can mimic other infections, it should be distinguished from oral ulcer, candidiasis, oral lichen planus, oral leukoplakia and so on. Case Presentation: This case report describes the patient with white plaques of the lingual mucosa for the secondary stage of syphilis in a 23-year-old male. It was a rare case that oral mucosal lesions as the only manifestations of secondary syphilis. And the differential diagnosis, treatment, follow-up visits and attentions were discussed. Conclusions: The clinicians need to distinguish the oral clinical presentations of syphilis from other oral diseases for suspected syphilis patients and to achieve early diagnosis and treatment. As well do a good job in relevant self-protection, instrument disinfection and management of nosocomial infection.
{"title":"Lingual Mucosal Lesions for Starting the Secondary Stage of Syphilis: A Case Report","authors":"Min Zhao","doi":"10.26502/acmcr.96550490","DOIUrl":"https://doi.org/10.26502/acmcr.96550490","url":null,"abstract":"Background: Recent years syphilis has the increased case rates among men who have sex with men and remains a continuing public health challenge globally. Owing to its varied manifestations of oral mucosa in syphilis that can mimic other infections, it should be distinguished from oral ulcer, candidiasis, oral lichen planus, oral leukoplakia and so on. Case Presentation: This case report describes the patient with white plaques of the lingual mucosa for the secondary stage of syphilis in a 23-year-old male. It was a rare case that oral mucosal lesions as the only manifestations of secondary syphilis. And the differential diagnosis, treatment, follow-up visits and attentions were discussed. Conclusions: The clinicians need to distinguish the oral clinical presentations of syphilis from other oral diseases for suspected syphilis patients and to achieve early diagnosis and treatment. As well do a good job in relevant self-protection, instrument disinfection and management of nosocomial infection.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Quast, S. Afzal, P. Leuders, M. Masyuk, K. Klein, M. Kelm, A. Polzin, T. Zeus
Post-myocardial infarction ventricular septal defect has become a rare event following ST Elevation Myocardial Infarction (STEMI) but is still a life-threatening complication with high mortality. Transcatheter closure of post-myocardial infarction ventricular septal defects has emerged as an alternative therapeutic approach but often requires individual strategies due to complex morphology. We report a case of a 62-year-old man who was admitted to our hospital after STEMI of the inferior wall with pulmonary congestion due to a post-myocardial infarction VSD for interdisciplinary evaluation and therapy. The patient was characterized by estimated high perioperative risk and underwent interventional closure of the VSD according to heart team decision. Because of ragged nature of the VSD closure with a conventional Occlutech VSD occluder was not possible. Therefore, we decided to close the defect using an off-lable device for ASD closure which Arch Clin Med Case Rep 2022; 6 (1): 66-71 DOI: 10.26502/acmcr.96550452 Archives of Clinical and Medical Case Reports 67 was successfully implanted without relevant residual shunt.
心肌梗死后室间隔缺损已成为ST段抬高型心肌梗死(STEMI)后的罕见事件,但仍是危及生命的高死亡率并发症。经导管关闭心肌梗死后室间隔缺损已成为一种替代治疗方法,但由于其复杂的形态学,往往需要个体策略。我们报告一例62岁男性患者,因心肌梗死后室间隔缺损(VSD)致下壁STEMI后肺充血而入院,以进行跨学科评估和治疗。患者的围手术期风险较高,根据心脏团队的决定,接受了室间隔关闭手术。由于VSD闭合的粗糙性,使用传统的Occlutech VSD闭塞器是不可能的。因此,我们决定使用一种可关闭ASD的设备来关闭缺陷,Arch clinmed Case Rep 2022;6 (1): 66-71 DOI: 10.26502/acmcr.96550452临床与医疗病例报告档案67例成功植入,无相关分流残留。
{"title":"Transcatheter Closure of a Ragged Post-Myocardial Infarction Ventricular Septal Defect Using an Off-Label ASD Occluder","authors":"C. Quast, S. Afzal, P. Leuders, M. Masyuk, K. Klein, M. Kelm, A. Polzin, T. Zeus","doi":"10.26502/acmcr.96550452","DOIUrl":"https://doi.org/10.26502/acmcr.96550452","url":null,"abstract":"Post-myocardial infarction ventricular septal defect has become a rare event following ST Elevation Myocardial Infarction (STEMI) but is still a life-threatening complication with high mortality. Transcatheter closure of post-myocardial infarction ventricular septal defects has emerged as an alternative therapeutic approach but often requires individual strategies due to complex morphology. We report a case of a 62-year-old man who was admitted to our hospital after STEMI of the inferior wall with pulmonary congestion due to a post-myocardial infarction VSD for interdisciplinary evaluation and therapy. The patient was characterized by estimated high perioperative risk and underwent interventional closure of the VSD according to heart team decision. Because of ragged nature of the VSD closure with a conventional Occlutech VSD occluder was not possible. Therefore, we decided to close the defect using an off-lable device for ASD closure which Arch Clin Med Case Rep 2022; 6 (1): 66-71 DOI: 10.26502/acmcr.96550452 Archives of Clinical and Medical Case Reports 67 was successfully implanted without relevant residual shunt.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muscle disease is referred to as myopathy. As a result, the muscles are less efficient than they might be. When muscles don't grow correctly, are injured, or are missing vital components, this might happen. Muscle atrophy is common in patients who have had Bronchial Asthma with Myopathy for a long time. Muscles lose mass and strength as a result of this fading away. We recently treated a patient who was experiencing some of the same issues. We suggested a Brain MRI and total spine screening to the patient which indicated hypoplasticity in the left transverse sinus. An X-Ray of the chest indicated that the left inferior nasal turbinate had expanded. Traditional therapies like acupuncture and massage, as well as modern techniques like multipurpose equipment and physiotherapy, were chosen to treat our patients. Our patient had wonderful success with these strategies. The procedure for the patient’s treatment has been completed. At the end of the 12th day of chest treatment, the patient was completely free of breathlessness. On the 10th day of acupuncture, the patient’s low back discomfort began to improve. At the end of the 20th day of therapy, the patient's headache begins to improve. Moreover, the authors believe that it is the first successful reported case in Bangladesh using these techniques. Arch Clin Med Case Rep 2022; 6 (1): 72-77 DOI: 10.26502/acmcr.96550453 Archives of Clinical and Medical Case Reports 73
肌肉疾病被称为肌病。因此,肌肉的效率比它们可能的要低。当肌肉不能正常生长、受伤或缺少重要成分时,就可能发生这种情况。肌肉萎缩常见于支气管哮喘伴肌病患者。肌肉失去质量和力量的结果是这种消退。我们最近治疗了一个病人,他也有同样的问题。我们建议对发现左横窦可塑性不足的患者进行脑MRI和全脊柱筛查。胸部x光片显示左下鼻甲扩张。我们选择了针灸和按摩等传统疗法,以及多功能设备和物理疗法等现代技术来治疗患者。我们的病人通过这些策略取得了巨大的成功。病人的治疗程序已经完成。胸部治疗第12天结束时,患者完全无呼吸困难。针灸第10天,患者腰背部不适开始改善。治疗第20天结束时,患者头痛开始好转。此外,作者认为,这是孟加拉国第一个使用这些技术成功报告的病例。Arch clinin Med Case Rep 2022;6 (1): 72-77 DOI: 10.26502/acmcr.96550453临床和医疗病例报告档案
{"title":"A Case Report on Bronchial Asthma with Myopathy","authors":"SM. Shahidul Islam, Rehana Akter Lima","doi":"10.26502/acmcr.96550453","DOIUrl":"https://doi.org/10.26502/acmcr.96550453","url":null,"abstract":"Muscle disease is referred to as myopathy. As a result, the muscles are less efficient than they might be. When muscles don't grow correctly, are injured, or are missing vital components, this might happen. Muscle atrophy is common in patients who have had Bronchial Asthma with Myopathy for a long time. Muscles lose mass and strength as a result of this fading away. We recently treated a patient who was experiencing some of the same issues. We suggested a Brain MRI and total spine screening to the patient which indicated hypoplasticity in the left transverse sinus. An X-Ray of the chest indicated that the left inferior nasal turbinate had expanded. Traditional therapies like acupuncture and massage, as well as modern techniques like multipurpose equipment and physiotherapy, were chosen to treat our patients. Our patient had wonderful success with these strategies. The procedure for the patient’s treatment has been completed. At the end of the 12th day of chest treatment, the patient was completely free of breathlessness. On the 10th day of acupuncture, the patient’s low back discomfort began to improve. At the end of the 20th day of therapy, the patient's headache begins to improve. Moreover, the authors believe that it is the first successful reported case in Bangladesh using these techniques. Arch Clin Med Case Rep 2022; 6 (1): 72-77 DOI: 10.26502/acmcr.96550453 Archives of Clinical and Medical Case Reports 73","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Karapantzou, Joao Pedro Vale, Frank Joachim Haubner, Konstantinos Zagoridis, Konstantinos Agas, Konstantinos Karagogos, Nikoleta Zagoridou, M. Canis
Background: Main subject of our investigation was to clarify, if a bilateral approach with Botulinum toxin type A injections is more efficient from cosmetic and functional aspect, compared to unilateral injections, in patients with one-sided facial hyperkinetic movements, like synkinesis and hemi facial spasm. Methods: Our patient cohort included 30 patients suffering from unilateral hyperkinetic facial contractions. We performed a total of 60 injections, 30 of them only on the Arch Clin Med Case Rep 2022; 6 (2): 149-172 DOI: 10.26502/acmcr.96550462 Archives of Clinical and Medical Case Reports 150 affected side and 30 on both facial sides. All participants underwent 2 botulinum toxin sessions, with a 4 months period lying between the injections. Our statistical analysis was divided into 4 hypothesis testing sub-groups, based on the results of the subjective satisfaction rates our patients delivered 2 months and 6 months after the initial botulinum toxin session. Furthermore 2 doctors evaluated the results based on pre-and after photographs on a Quartile Grading Scale for objective evaluation for the same time periods. Each one of the observers received one patient group, either with bilateral or with ipsilateral treatments, without knowing which group they received. Results: Summarizing the statistical results we analyzed from both sources (patients and doc-tors-observers), we found statistically significant differences in satisfaction rate between the two groups (p=.004) and a better objective evaluation on patients who underwent combined treatments. Conclusions: Our work confirmed the initial assumption that patients with facial asymmetry of different etiology benefit from a bilateral therapeutic approach with botulinum toxin injections, instead of one-sided injections into the hyperkinetic or dyskinesia facial side.
{"title":"Bilateral Approach with Botulinum Toxin Type A Injections in Patients with One-Sided Facial Hyperkinetic Movements","authors":"C. Karapantzou, Joao Pedro Vale, Frank Joachim Haubner, Konstantinos Zagoridis, Konstantinos Agas, Konstantinos Karagogos, Nikoleta Zagoridou, M. Canis","doi":"10.26502/acmcr.96550462","DOIUrl":"https://doi.org/10.26502/acmcr.96550462","url":null,"abstract":"Background: Main subject of our investigation was to clarify, if a bilateral approach with Botulinum toxin type A injections is more efficient from cosmetic and functional aspect, compared to unilateral injections, in patients with one-sided facial hyperkinetic movements, like synkinesis and hemi facial spasm. Methods: Our patient cohort included 30 patients suffering from unilateral hyperkinetic facial contractions. We performed a total of 60 injections, 30 of them only on the Arch Clin Med Case Rep 2022; 6 (2): 149-172 DOI: 10.26502/acmcr.96550462 Archives of Clinical and Medical Case Reports 150 affected side and 30 on both facial sides. All participants underwent 2 botulinum toxin sessions, with a 4 months period lying between the injections. Our statistical analysis was divided into 4 hypothesis testing sub-groups, based on the results of the subjective satisfaction rates our patients delivered 2 months and 6 months after the initial botulinum toxin session. Furthermore 2 doctors evaluated the results based on pre-and after photographs on a Quartile Grading Scale for objective evaluation for the same time periods. Each one of the observers received one patient group, either with bilateral or with ipsilateral treatments, without knowing which group they received. Results: Summarizing the statistical results we analyzed from both sources (patients and doc-tors-observers), we found statistically significant differences in satisfaction rate between the two groups (p=.004) and a better objective evaluation on patients who underwent combined treatments. Conclusions: Our work confirmed the initial assumption that patients with facial asymmetry of different etiology benefit from a bilateral therapeutic approach with botulinum toxin injections, instead of one-sided injections into the hyperkinetic or dyskinesia facial side.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
1. Case Report A 79-year-old woman with no significant medical history visited an emergency room with a complaint of diplopia. Ocular motility disorder was noted, and a central lesion was suspected. Contrast-enhanced computed tomography (CT) revealed a cystic lesion, and cyst infection was suspected based on the rim enhancement. Coronal images (Figure 1) suggested a frontal sinus cyst, but horizontal (Figure 2) and sagittal (Figure 3) sections revealed a Supraorbital Ethmoid-Cell (SOEC) cyst extending into the orbit. Diplopia disappeared immediately after endoscopic surgery for cyst enucleation. Anatomically, SOECs are associated with the anterior ethmoidal artery (AEA), which runs within or in continuity with the posterior border of the SOEC opening [1] (Figure 4). Therefore, in endoscopic surgery, the risk of AEA damage increases with a posterior approach, and an approach from the front is recommended. If an axillary flap [2] is not created and the nasal ridge is not sufficiently excised, it is difficult to operate using an endoscope.
{"title":"Diagnosis and Treatment of an Infected Supraorbital Ethmoid Cell Cyst","authors":"K. Koda, K. Yasuhara","doi":"10.26502/acmcr.96550467","DOIUrl":"https://doi.org/10.26502/acmcr.96550467","url":null,"abstract":"1. Case Report A 79-year-old woman with no significant medical history visited an emergency room with a complaint of diplopia. Ocular motility disorder was noted, and a central lesion was suspected. Contrast-enhanced computed tomography (CT) revealed a cystic lesion, and cyst infection was suspected based on the rim enhancement. Coronal images (Figure 1) suggested a frontal sinus cyst, but horizontal (Figure 2) and sagittal (Figure 3) sections revealed a Supraorbital Ethmoid-Cell (SOEC) cyst extending into the orbit. Diplopia disappeared immediately after endoscopic surgery for cyst enucleation. Anatomically, SOECs are associated with the anterior ethmoidal artery (AEA), which runs within or in continuity with the posterior border of the SOEC opening [1] (Figure 4). Therefore, in endoscopic surgery, the risk of AEA damage increases with a posterior approach, and an approach from the front is recommended. If an axillary flap [2] is not created and the nasal ridge is not sufficiently excised, it is difficult to operate using an endoscope.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johanna Sophie Pohl, F. Leypoldt, Naomi Larsen, A. van Baalen, K. Wandinger, K. Rostásy, H. Muhle
Recently, several case series have described pediatric patients presenting with new onset focal seizures together with relapsing fever and cortical T2/FLAIR hyperintensities in association with myelin oligodendrocyte glycoprotein (MOG) antibodies, in adults known as unilateral cortical fluid-attenuated inversion recovery (FLAIR) hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES). A previously healthy 12-year-old girl first arrived to the emergency department with stroke-like symptoms, including hemiparesis, facial palsy, and severe headache. Heparin therapy was initiated; seizures were successfully treated with valproate. Due to persistent cortical edema in brain magnetic resonance imaging (MRI), anti-inflammatory treatment with high dose dexamethasone was initiated and led to prompt recovery. One month later, the patient displayed fever and headache of unknown origin. Brain MRI showed cortical FLAIR hyperintensities and leptomeningeal contrast enhancement. Cerebrospinal fluid (CSF) analyses including autoimmune diagnostics revealed a lymphocytic pleocytosis, elevated protein, and positive oligoclonal bands. MOG antibodies in serum and CSF were positive. Intravenous methylprednisolone (IVMP), followed by oral tapering, led to complete recovery, yet one relapse occurred and intravenous immunoglobulins (IVIG) were added, given monthly to date. Our patient remained relapse-free for eight months when moderate but persisting headache and paraesthesia reoccurred. Methylprednisolone therapy was given, but outstanding MOG antibodies in serum and CSF were negative. Therefore, maintenance therapy was not extended. Single focal seizures led to adjustment of antiseizure medication. In summary, this is the first case report of a pediatric patient with MOG encephalitis, first presenting stroke-like symptoms, reminiscent of the newly described FLAMES syndrome.
{"title":"Peracute Onset Pediatric Myelin Oligodendrocyte Glycoprotein Antibody Associated Focal Cortical Encephalitis: A Case Report","authors":"Johanna Sophie Pohl, F. Leypoldt, Naomi Larsen, A. van Baalen, K. Wandinger, K. Rostásy, H. Muhle","doi":"10.26502/acmcr.96550522","DOIUrl":"https://doi.org/10.26502/acmcr.96550522","url":null,"abstract":"Recently, several case series have described pediatric patients presenting with new onset focal seizures together with relapsing fever and cortical T2/FLAIR hyperintensities in association with myelin oligodendrocyte glycoprotein (MOG) antibodies, in adults known as unilateral cortical fluid-attenuated inversion recovery (FLAIR) hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES). A previously healthy 12-year-old girl first arrived to the emergency department with stroke-like symptoms, including hemiparesis, facial palsy, and severe headache. Heparin therapy was initiated; seizures were successfully treated with valproate. Due to persistent cortical edema in brain magnetic resonance imaging (MRI), anti-inflammatory treatment with high dose dexamethasone was initiated and led to prompt recovery. One month later, the patient displayed fever and headache of unknown origin. Brain MRI showed cortical FLAIR hyperintensities and leptomeningeal contrast enhancement. Cerebrospinal fluid (CSF) analyses including autoimmune diagnostics revealed a lymphocytic pleocytosis, elevated protein, and positive oligoclonal bands. MOG antibodies in serum and CSF were positive. Intravenous methylprednisolone (IVMP), followed by oral tapering, led to complete recovery, yet one relapse occurred and intravenous immunoglobulins (IVIG) were added, given monthly to date. Our patient remained relapse-free for eight months when moderate but persisting headache and paraesthesia reoccurred. Methylprednisolone therapy was given, but outstanding MOG antibodies in serum and CSF were negative. Therefore, maintenance therapy was not extended. Single focal seizures led to adjustment of antiseizure medication. In summary, this is the first case report of a pediatric patient with MOG encephalitis, first presenting stroke-like symptoms, reminiscent of the newly described FLAMES syndrome.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Morena Emanuele, Lucchi Matteo, Romano Carmela, Petrucci Simona, Tartaglia Matteo, Morosetti Roberta, Conte Antonella, Buscarinu Maria Chiara, Romano Silvia, Salvetti Marco, Mirabella Massimiliano, Ristori Giovanni
Affiliation: 1Centre for Experimental Neurological Therapies (CENTERS), Department of Neurosciences, Mental Health and Sensory Organs, Sapienza University of Rome, Rome, Italy 2Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Istituto di Neurologia, Università Cattolica del Sacro Cuore, Rome, Italy 3Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy 4Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy 5Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy 6Neuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy
Affiliation:1Centre for实验Neurological Therapies(中心),Department of Neurosciences Mental Health and Sensory Organs罗马智慧大学、罗马、意大利2Fondazione大学综合医院”A .双胞胎“IRCCS、神经病学研究所、圣心天主教大学、罗马、意大利3Department of神经学and Psychiatry Sapienza University of罗马,罗马,意大利4Department of Human Neurosciences,罗马,罗马智慧大学,地中海神经医学研究所,波兹利,意大利神经免疫学股,圣卢西亚,罗马,意大利
{"title":"CADASIL or MS? Consider “Red Flags” but Avoid a Misdiagnosis: Case Series of a Concomitant Diagnosis","authors":"Morena Emanuele, Lucchi Matteo, Romano Carmela, Petrucci Simona, Tartaglia Matteo, Morosetti Roberta, Conte Antonella, Buscarinu Maria Chiara, Romano Silvia, Salvetti Marco, Mirabella Massimiliano, Ristori Giovanni","doi":"10.26502/acmcr.96550530","DOIUrl":"https://doi.org/10.26502/acmcr.96550530","url":null,"abstract":"Affiliation: 1Centre for Experimental Neurological Therapies (CENTERS), Department of Neurosciences, Mental Health and Sensory Organs, Sapienza University of Rome, Rome, Italy 2Fondazione Policlinico Universitario \"A. Gemelli\" IRCCS, Istituto di Neurologia, Università Cattolica del Sacro Cuore, Rome, Italy 3Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy 4Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy 5Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy 6Neuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patients with end-stage kidney disease are under an increased risk for morbidity and mortality due to cardiovascular reasons. Yet, patients might show only atypical symptoms during cardiac events and routinely performed pre-transplant diagnostic measures are discussed controversially. A heart transplanted 50-year-old male with end-stage kidney disease was assessed for kidney transplantation. Myocardial scintigraphy, chest x-ray, pulmonary function test, urological and gastrointestinal assessment showed normal results. A routinely performed blood test revealed elevated procalcitonin, C-reactive protein and leucocytes. Measured vital parameters and physical examination revealed no pathologies. Coughing, shortness of breath or chest pain were denied. CT-scan showed no signs of infection but lack of contrast media enhancement in the heart. Myocardial infarction was confirmed in electrocardiogram and transthoracic echocardiogram demonstrated an impaired ejection fraction of 20%. Treatment with anti-platelet medication and anticoagulation was followed by invasive heart catheterization, which revealed no acute stenosis but a dissolved in-stent thrombosis. Since kidney failure was progressing the patient required dialysis treatment. Microbiological analyses of blood and urine samples stayed negative. Chronic kidney disease patients are at increased cardiovascular risk. However, invasiveness of cardiac diagnostics for potential kidney transplant is debated controversially. KDIGO guideline 2020 advises non-invasive screening for coronary artery disease for asymptomatic patients at high risk. However, there is no specific guideline for previously heart transplanted candidates for kidney transplant and patients with high pretest probability benefit from invasive diagnostics. A risk stratification for cardiac complications and pre-kidney transplant evaluation should be executed in clinical practice.
{"title":"Unexpected Elevation of Infection Parameters in a Heart Transplanted Patient with Chronic Kidney Disease: A Case Report","authors":"Kurzhagen Jt, Roeder Ss, M. J","doi":"10.26502/acmcr.96550558","DOIUrl":"https://doi.org/10.26502/acmcr.96550558","url":null,"abstract":"Patients with end-stage kidney disease are under an increased risk for morbidity and mortality due to cardiovascular reasons. Yet, patients might show only atypical symptoms during cardiac events and routinely performed pre-transplant diagnostic measures are discussed controversially. A heart transplanted 50-year-old male with end-stage kidney disease was assessed for kidney transplantation. Myocardial scintigraphy, chest x-ray, pulmonary function test, urological and gastrointestinal assessment showed normal results. A routinely performed blood test revealed elevated procalcitonin, C-reactive protein and leucocytes. Measured vital parameters and physical examination revealed no pathologies. Coughing, shortness of breath or chest pain were denied. CT-scan showed no signs of infection but lack of contrast media enhancement in the heart. Myocardial infarction was confirmed in electrocardiogram and transthoracic echocardiogram demonstrated an impaired ejection fraction of 20%. Treatment with anti-platelet medication and anticoagulation was followed by invasive heart catheterization, which revealed no acute stenosis but a dissolved in-stent thrombosis. Since kidney failure was progressing the patient required dialysis treatment. Microbiological analyses of blood and urine samples stayed negative. Chronic kidney disease patients are at increased cardiovascular risk. However, invasiveness of cardiac diagnostics for potential kidney transplant is debated controversially. KDIGO guideline 2020 advises non-invasive screening for coronary artery disease for asymptomatic patients at high risk. However, there is no specific guideline for previously heart transplanted candidates for kidney transplant and patients with high pretest probability benefit from invasive diagnostics. A risk stratification for cardiac complications and pre-kidney transplant evaluation should be executed in clinical practice.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A middle-aged male who is known to have acne vulgaris on oral treatment complaining of hematochezia containing blood clots for few weeks. The patient underwent colonoscopy displaying several left colon blue rubber blebs and here we are presenting this rare case.
{"title":"Lower GI Bleeding and Left Colon Blue Rubber Blebs: Rare Case Report","authors":"Fahad Al-Lhedan, A. Kurdi","doi":"10.26502/acmcr.96550560","DOIUrl":"https://doi.org/10.26502/acmcr.96550560","url":null,"abstract":"A middle-aged male who is known to have acne vulgaris on oral treatment complaining of hematochezia containing blood clots for few weeks. The patient underwent colonoscopy displaying several left colon blue rubber blebs and here we are presenting this rare case.","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69344278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Srimanth Kumar Barigela, Rajesh Kumar Galimudi, Shivani Kadarla, Durga Neeharika Rani, Pardha P. Reddy, Madhavi Jangala, Sunita G Kumar
Knowledge, Attitude and Perceptions towards COVID-19
对COVID-19的知识、态度和看法
{"title":"Knowledge, Attitude and Perceptions towards COVID-19 Vaccination among South Indian (Telangana) Population - A Cross Sectional Study","authors":"Srimanth Kumar Barigela, Rajesh Kumar Galimudi, Shivani Kadarla, Durga Neeharika Rani, Pardha P. Reddy, Madhavi Jangala, Sunita G Kumar","doi":"10.26502/acmcr.96550485","DOIUrl":"https://doi.org/10.26502/acmcr.96550485","url":null,"abstract":"Knowledge, Attitude and Perceptions towards COVID-19","PeriodicalId":72280,"journal":{"name":"Archives of clinical and medical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69343377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}