M. Bassi, C. Manzitti, Shana Montalto, S. Giglio, M. Conte, Fabio Facco, L. Amoroso
{"title":"Pseudohyponatremia in a neuroblastoma patient with obstructive jaundice and review of literature","authors":"M. Bassi, C. Manzitti, Shana Montalto, S. Giglio, M. Conte, Fabio Facco, L. Amoroso","doi":"10.15761/ccrr.1000504","DOIUrl":"https://doi.org/10.15761/ccrr.1000504","url":null,"abstract":"","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67449289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Rani, R. Mehra, Sunita Dubey, S. Wadhwani, K. Abhishek
{"title":"Spontaneous rupture of subcapsular liver hematoma in sudden onset severe preeclampsia","authors":"S. Rani, R. Mehra, Sunita Dubey, S. Wadhwani, K. Abhishek","doi":"10.15761/ccrr.1000505","DOIUrl":"https://doi.org/10.15761/ccrr.1000505","url":null,"abstract":"","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67449391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
López-Cabrera Yessica, Aguilar-Silva Andrés, Del Carpio Orantes Luis, Chavez Aguilar Cecilia, Cerda Mendez Carlos Ivan, Onofre Aquino Raquel
The incidence varies according to regions, with a predominance in pediatric patients. In adults, there has been an average age of onset at 50 years with a female predominance in a 1:7 with respect to the men [3]. An estimated worldwide incidence of 1.2 cases per million inhabitants. In Latin America, there is no standardized report that allows establishing epidemiological data, with an estimated survival of 38% one year after diagnosis [4] (Figure 1). However, this figure may be underestimated as it is a diagnosis of exclusion and due to the lack of specificity of the clinical picture.
{"title":"Case report of Hemophagocytic Syndrome complicated by septic shock","authors":"López-Cabrera Yessica, Aguilar-Silva Andrés, Del Carpio Orantes Luis, Chavez Aguilar Cecilia, Cerda Mendez Carlos Ivan, Onofre Aquino Raquel","doi":"10.15761/CCRR.1000495","DOIUrl":"https://doi.org/10.15761/CCRR.1000495","url":null,"abstract":"The incidence varies according to regions, with a predominance in pediatric patients. In adults, there has been an average age of onset at 50 years with a female predominance in a 1:7 with respect to the men [3]. An estimated worldwide incidence of 1.2 cases per million inhabitants. In Latin America, there is no standardized report that allows establishing epidemiological data, with an estimated survival of 38% one year after diagnosis [4] (Figure 1). However, this figure may be underestimated as it is a diagnosis of exclusion and due to the lack of specificity of the clinical picture.","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67448849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Burdening of healthcare system by expected second wave of COVID-19 with influenza co-infection","authors":"K. Bhatt, M. Sanchez-Gonzalez","doi":"10.33425/2693-1516.1008","DOIUrl":"https://doi.org/10.33425/2693-1516.1008","url":null,"abstract":"","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79630163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Sottilotta, C. Mangano, R. Basile, F. Luise, Demetrio Megalizzi, G. Nicolò, V. Oriana, A. Piromalli
{"title":"Management of heparin in COVID-19 patients during the first phase of pandemic","authors":"G. Sottilotta, C. Mangano, R. Basile, F. Luise, Demetrio Megalizzi, G. Nicolò, V. Oriana, A. Piromalli","doi":"10.33425/2693-1516.1009","DOIUrl":"https://doi.org/10.33425/2693-1516.1009","url":null,"abstract":"","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83848287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-31DOI: 10.29011/2642-3243.100135
Navid Forouhar, Amir Forouhar
Nowadays, public participation is one of the most important factors to improve the feasibility, legitimacy, and quality of urban plans. In Iran, due to a lack of comprehensive understanding of the participation notion and its necessary socio-economic and political infrastructures, participatory decision-making has faced some serious challenges in both processes of preparing and implementing. This paper focuses on practical strategies for preparing participatory urban plans. Also, it seeks to answer this question: What is the role of planners to prepare a real participatory planning? It is presumed that a conceptual model for participatory planning can be fitted with Iran’s conditions using integrating the fundamental philosophic ideas of participatory planning such as theories of Paul Michel Foucault and Jürgen Habermas, given the fact that the present participatory planning in Iran needs a supportive theory which is adopted with power structures in Iranian urban planning system. In this regard, Habermas’ theory of communicative action and Foucault’s theory of power structures are reviewed by a comparative analysis method to present an integrated conceptual model for participatory planning in Iran’s condition. Finally, the CDS-making process in Anzali of Iran is analyzed to examine this claim in practice. The results yield that enabling urban planners to act as communication facilitators during planning can propel the participatory planning from theory to a real practice by integrating the positive aspects of communication and power.
{"title":"Evaluating the role of urban planners in participatory urban planning: A conceptual model of success in Iran","authors":"Navid Forouhar, Amir Forouhar","doi":"10.29011/2642-3243.100135","DOIUrl":"https://doi.org/10.29011/2642-3243.100135","url":null,"abstract":"Nowadays, public participation is one of the most important factors to improve the feasibility, legitimacy, and quality of urban plans. In Iran, due to a lack of comprehensive understanding of the participation notion and its necessary socio-economic and political infrastructures, participatory decision-making has faced some serious challenges in both processes of preparing and implementing. This paper focuses on practical strategies for preparing participatory urban plans. Also, it seeks to answer this question: What is the role of planners to prepare a real participatory planning? It is presumed that a conceptual model for participatory planning can be fitted with Iran’s conditions using integrating the fundamental philosophic ideas of participatory planning such as theories of Paul Michel Foucault and Jürgen Habermas, given the fact that the present participatory planning in Iran needs a supportive theory which is adopted with power structures in Iranian urban planning system. In this regard, Habermas’ theory of communicative action and Foucault’s theory of power structures are reviewed by a comparative analysis method to present an integrated conceptual model for participatory planning in Iran’s condition. Finally, the CDS-making process in Anzali of Iran is analyzed to examine this claim in practice. The results yield that enabling urban planners to act as communication facilitators during planning can propel the participatory planning from theory to a real practice by integrating the positive aspects of communication and power.","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80061412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Common signs of corona virus infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death. People who are suffering from prevailing chronic diseases such as cancer, heart disease, high blood pressure, diabetes, chronic kidney disease, etc. may die due to their weaker immunity system. Most of the people around the world died due to panic attack and due to extreme fear. A fear of not having vaccination for the virus infections has also taken a big death toll. Therefore, it is very important to build a stronger robust immune system and patients need to think positive and follow the positive approach to combat the disease. We will discuss 3 things in these articles. Understand energy concepts of the disease and healing of the same How to boost our immune system either through a natural way or through energy healing system? How does our subconscious mind contribute to the illness and death?
{"title":"Coronaviruses are zoonotic, meaning they are transmitted between animals and people","authors":"V. Kamath","doi":"10.15761/ccrr.1000476","DOIUrl":"https://doi.org/10.15761/ccrr.1000476","url":null,"abstract":"Common signs of corona virus infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death. People who are suffering from prevailing chronic diseases such as cancer, heart disease, high blood pressure, diabetes, chronic kidney disease, etc. may die due to their weaker immunity system. Most of the people around the world died due to panic attack and due to extreme fear. A fear of not having vaccination for the virus infections has also taken a big death toll. Therefore, it is very important to build a stronger robust immune system and patients need to think positive and follow the positive approach to combat the disease. \u0000 \u0000We will discuss 3 things in these articles. \u0000 \u0000 \u0000 Understand energy concepts of the disease and healing of the same \u0000 How to boost our immune system either through a natural way or through energy healing system? \u0000 \u0000 \u0000How does our subconscious mind contribute to the illness and death?","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47206372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eliza Baird Daniel, Douglas E Ney, Jean M Mulcahy Levy
Gangliogliomas are predominantly low-grade primary brain tumors comprised of neuronal and glial components that are found in both pediatric and young adult populations. In the majority of cases, surgical resection of these tumors is curative. However, tumor location in eloquent centers of the brain can make surgical intervention inappropriate. Additionally, a subset of tumors progress to anaplastic ganglioglioma which carries a poor prognosis, despite resection. Activating mutations in the MAPK pathway, such as BRAF V600E, have been identified in many of these tumors. Tumors carrying such mutations have demonstrated susceptibility to MEK inhibition therapy. However, there remains a subset of ganglioglioma that do not contain a known mutation in the MAPK pathway and thus have not been targeted with MEK inhibition therapy. Here, we present a young adult ganglioglioma patient without identified MAPK pathway activation mutations who demonstrated a significant and sustained response to MEK inhibition with trametinib.
{"title":"MEK inhibition with trametinib is a successful therapy in ganglioglioma.","authors":"Eliza Baird Daniel, Douglas E Ney, Jean M Mulcahy Levy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gangliogliomas are predominantly low-grade primary brain tumors comprised of neuronal and glial components that are found in both pediatric and young adult populations. In the majority of cases, surgical resection of these tumors is curative. However, tumor location in eloquent centers of the brain can make surgical intervention inappropriate. Additionally, a subset of tumors progress to anaplastic ganglioglioma which carries a poor prognosis, despite resection. Activating mutations in the MAPK pathway, such as BRAF V600E, have been identified in many of these tumors. Tumors carrying such mutations have demonstrated susceptibility to MEK inhibition therapy. However, there remains a subset of ganglioglioma that do not contain a known mutation in the MAPK pathway and thus have not been targeted with MEK inhibition therapy. Here, we present a young adult ganglioglioma patient without identified MAPK pathway activation mutations who demonstrated a significant and sustained response to MEK inhibition with trametinib.</p>","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38540967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gangliogliomas are predominantly low-grade primary brain tumors comprised of neuronal and glial components that are found in both pediatric and young adult populations. In the majority of cases, surgical resection of these tumors is curative. However, tumor location in eloquent centers of the brain can make surgical intervention inappropriate. Additionally, a subset of tumors progress to anaplastic ganglioglioma which carries a poor prognosis, despite resection. Activating mutations in the MAPK pathway, such as BRAF V600E, have been identified in many of these tumors. Tumors carrying such mutations have demonstrated susceptibility to MEK inhibition therapy. However, there remains a subset of ganglioglioma that do not contain a known mutation in the MAPK pathway and thus have not been targeted with MEK inhibition therapy. Here, we present a young adult ganglioglioma patient without identified MAPK pathway activation mutations who demonstrated a significant and sustained response to MEK inhibition with trametinib.
{"title":"MEK inhibition with trametinib is a successful therapy in ganglioglioma","authors":"E. Daniel, D. Ney, J. Levy","doi":"10.15761/ccrr.1000479","DOIUrl":"https://doi.org/10.15761/ccrr.1000479","url":null,"abstract":"Gangliogliomas are predominantly low-grade primary brain tumors comprised of neuronal and glial components that are found in both pediatric and young adult populations. In the majority of cases, surgical resection of these tumors is curative. However, tumor location in eloquent centers of the brain can make surgical intervention inappropriate. Additionally, a subset of tumors progress to anaplastic ganglioglioma which carries a poor prognosis, despite resection. Activating mutations in the MAPK pathway, such as BRAF V600E, have been identified in many of these tumors. Tumors carrying such mutations have demonstrated susceptibility to MEK inhibition therapy. However, there remains a subset of ganglioglioma that do not contain a known mutation in the MAPK pathway and thus have not been targeted with MEK inhibition therapy. Here, we present a young adult ganglioglioma patient without identified MAPK pathway activation mutations who demonstrated a significant and sustained response to MEK inhibition with trametinib.","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45223660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheila Maria Lins Bentes, Marcos do Nascimento Bentes, K. C. Bertoncello, Jussara Gue Martini, Fernanda Neves, M. D. L. D. Souza
During pregnancy, women go through physiological and psychosocial changes considered normal at this phase; on average one in five women have symptoms of distress. Having to face a disease prone to cause congenital abnormalities in the fetus or newborn further increases the psychological stress of pregnant women. The multidisciplinary team must ensure the physical and psychological well-being of these pregnant women throughout pregnancy [1].
{"title":"Zika virus infection in the Brazilian Amazon: A case report","authors":"Cheila Maria Lins Bentes, Marcos do Nascimento Bentes, K. C. Bertoncello, Jussara Gue Martini, Fernanda Neves, M. D. L. D. Souza","doi":"10.15761/ccrr.1000478","DOIUrl":"https://doi.org/10.15761/ccrr.1000478","url":null,"abstract":"During pregnancy, women go through physiological and psychosocial changes considered normal at this phase; on average one in five women have symptoms of distress. Having to face a disease prone to cause congenital abnormalities in the fetus or newborn further increases the psychological stress of pregnant women. The multidisciplinary team must ensure the physical and psychological well-being of these pregnant women throughout pregnancy [1].","PeriodicalId":72607,"journal":{"name":"Clinical case reports and reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67447835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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