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Association of lupus and a frontal fibrosing alopecia: A case report 狼疮与额部纤维化性脱发的关系:1例报告
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000473
J. Ziani, Sara Eloudi, S. Benkirane, H. Baybay, Z. Douhi, F. Mernissi
There are few reports of the association between Frontal Fibrosing Alopecia (AFF) and lupus. Lupus erythematosus is a recurrent chronic disease accompanied by acute, subacute and chronic lesions. Telogen Effluvium occurs as part of the systemic activity of the disease, and scarring alopecia results from discoid lesions on the scalp. Other types of alopecia, such as alopecia areata, can sometimes be found in lupus. AFF is a typical form of cicatricial alopecia. It can also lead to the development of tiny papules on the frontotemporal region. It occurs mainly in postmenopausal women. The coexistence of AFF and Lupus erythematosus, as observed in our patient, may be indicative of a common pathogenic background. *Correspondence to: Jihane Ziani, Department of Dermatology, Hassan II university Hospital, Fez, Morocco, E-mail: dr.zianijihane@gmail.com
额部纤维化性脱发(AFF)与狼疮之间的关联很少有报道。红斑狼疮是一种复发性慢性疾病,伴有急性、亚急性和慢性病变。休止期脱发是该病全身活动的一部分,而瘢痕性脱发是由头皮上的盘状病变引起的。其他类型的脱发,如斑秃,有时可以在狼疮中发现。AFF是一种典型的瘢痕性脱发。它还会导致额颞区出现小丘疹。它主要发生在绝经后的妇女。AFF和红斑狼疮的共存,正如我们的病人所观察到的,可能表明有共同的致病背景。*通讯:Jihane Ziani,摩洛哥非斯哈桑二世大学医院皮肤科,E-mail: dr.zianijihane@gmail.com
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引用次数: 0
Repair of the left ventricular wall pseudoaneurysm following myocardial infarction (simple modified dor technique) 心肌梗死后左心室壁假性动脉瘤的修复(简单改良门技术)
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000483
M. Maleki, N. Azdaki, Mohammad Reza Rezvani, Alireza Rahmani Motlaq
A rare however serious complication of myocardial infarction is left ventricular pseudoaneurysm that requires urgent intervention to avoid unforeseeable fatal rupture. Here, we present a successful repair of posterolateral and basal left ventricular pseudoaneurysm case, using a modified Dor technique.
左心室假性动脉瘤是一种罕见但严重的心肌梗死并发症,需要紧急干预以避免不可预见的致命破裂。在这里,我们提出一个成功的修复后外侧和基底左心室假性动脉瘤的情况下,使用改良的Dor技术。
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引用次数: 0
Objective tinnitus due to essential palatal myoclonus 目的:原发性腭肌阵挛所致耳鸣
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000486
Daryus Heydari, L. Eker, H. Kayali
Objective tinnitus can be heard by both the patient him or herself and examiner. Objective tinnitus can be treated in many cases by medicines like muscle relaxants, anti-convulsatants, barbiturates, benzodiazepines, and anti-cholinerjics or can be treated by surgically. To the best of our knowledge in medical treatment there is not use of gabapentin for medical treatment of objective tinnitus. In this report a woman 40 y-old has for a long time objective tinnitus was presented.. She was treated by gabapentin and full recovery was observed.
客观耳鸣既可由患者本人听到,也可由检查者听到。目的:在许多情况下,耳鸣可以通过肌肉松弛剂、抗惊厥药、巴比妥类药物、苯二氮卓类药物和抗胆碱类药物等药物治疗,也可以通过手术治疗。据我们所知,目前还没有加巴喷丁用于客观耳鸣的医学治疗。本文报告一位40岁女性长期客观耳鸣。加巴喷丁治疗后完全康复。
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引用次数: 0
Metastatic choriocarcinoma with tumour lysis syndrome 转移性绒毛膜癌伴肿瘤溶解综合征
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000472
Birthe Osorio, H. Männle, K. Münstedt
We report on a 32-year-old woman, gravida 5, para 2 who presented with a rapidly growing process of a choriocarcinoma after spontaneous birth. Two weeks after delivery, the patient suffered from dyspnoe, tachycardia and two large ovarian cysts. Diagnostic showed a metastasis choriocarcinoma in the lung. After the first application of chemotherapy according to the EMACO protocol the patient degraded quickly. She had a respiratory distress syndrome and an endotracheal intubation was necessary. We suspected a massive tumour cell lysis with haemorrhage after chemotherapy. Tumourlysis syndrome in choriocarcinoma is a rare complication as it is in solid tumours. Treatment in the intensive care unit allowed continuation of chemotherapy with EMACO. The general health state of the patient improves slowly and ß-HCG falled. After 78 days of hospitalization the patient was able to be discharged from hospital.
我们报告一位32岁妇女,妊娠5期,第2段,在自然分娩后出现绒毛膜癌的快速生长过程。分娩后两周,患者出现呼吸困难、心动过速和两个大卵巢囊肿。诊断为肺转移性绒毛膜癌。根据EMACO方案首次应用化疗后,患者迅速退化。她有呼吸窘迫综合征,需要气管插管。我们怀疑化疗后有大量肿瘤细胞溶解并出血。绒毛膜癌的肿瘤溶解综合征是一种罕见的并发症,因为它是在实体肿瘤。在重症监护病房的治疗允许继续使用EMACO进行化疗。患者总体健康状况改善缓慢,ß-HCG下降。住院78天后,患者得以出院。
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引用次数: 0
The psychological impact of COVID-19 pandemic on Pakistani population: Managing challenges through mental health services 2019冠状病毒病大流行对巴基斯坦人口的心理影响:通过精神卫生服务应对挑战
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000482
K. Junaid, Hassan Ali, Maryam Khalid
The Novel Coronavirus which causes COVID-19 is the ongoing global public health emergency and the greatest challenge we are facing nowadays. Wuhan, Hubei, China was the place where this disease was first recognized in December 2019. On March 11, 2020, this disease was declared a pandemic by World Health Organization (WHO). It also has been announced as a Public Health Emergency of International Concern on January 30, 2020 by World Health Organization (WHO) [1]. As of 15th May 2020, the novel Coronavirus has affected more than 4,527,165 people around the world and has taken more than 303,416 lives and has spread to more than 210 countries and territories. By February 2020, the Coronavirus was confirmed to have reached in Pakistan and there were 37218 total cases, 10,155 recoveries and 803 deaths as of 15th May 2020 [2]. In order to control this situation, the Government of Pakistan has issued a series of national and provincial guidelines such as limiting travel, social distancing, strict quarantine measures and closure of educational institutes all over the country and these guidelines have been disseminated on various channels successfully [3].
引起COVID-19的新型冠状病毒是当前全球突发公共卫生事件,也是我们面临的最大挑战。中国湖北省武汉市是2019年12月首次发现这种疾病的地方。2020年3月11日,世界卫生组织宣布该病为大流行。世界卫生组织(世卫组织)于2020年1月30日宣布它为国际关注的突发公共卫生事件。截至2020年5月15日,新型冠状病毒已在全球影响了4527165多人,夺走了303416多人的生命,并已蔓延到210多个国家和地区。截至2020年2月,新冠病毒已被证实在巴基斯坦传播,截至2020年5月15日,巴基斯坦共有37218例病例,10155例康复,803例死亡。为了控制这一局势,巴基斯坦政府发布了一系列国家和省级指导方针,如限制旅行、保持社会距离、严格隔离措施和关闭全国各地的教育机构,这些指导方针已通过各种渠道成功传播。
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引用次数: 2
Biweekly cladribine and rituximab in a patient with hairy cell leukemia and severe renal failure 两周克拉德里滨联合利妥昔单抗治疗毛细胞白血病合并严重肾功能衰竭1例
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000485
E. Ranković, S. Dotlic, P. Rončević, M. Vodanović, I. Aurer
Hairy cell leukemia (HCL) is a rare indolent lymphoproliferative disorder usually clinically characterized by pancytopenia and splenomegaly. It is very sensitive to purine analogues cladribine and pentostatin which are both primarily excreted by kidneys and registration labels bear warnings against their use in patients with severe renal insufficiency. We report a patient with HCL and severe renal failure who was successfully treated with five subcutaneous injections of cladribine 0.14 mg/ kg and six biweekly infusions of rituximab 375 mg/2 iv. This regimen was tolerated remarkably well without cumbersome side–effects. Our case-report suggests that cladribine can be efficaciously and safely used in patients with severe renal insufficiency if administered in standard doses once every two weeks.
毛细胞白血病(HCL)是一种罕见的惰性淋巴细胞增生性疾病,临床上通常以全血细胞减少和脾肿大为特征。它对嘌呤类似物氯德里滨和戊他汀非常敏感,这两种药物主要由肾脏排泄,注册标签上有警告,禁止严重肾功能不全患者使用。我们报告了一位HCL合并严重肾衰竭的患者,他成功地接受了5次皮下注射0.14 mg/ kg的克拉德里滨和6次每两周输注375 mg/ 2iv的利妥昔单抗。该方案的耐受性非常好,没有麻烦的副作用。我们的病例报告表明,如果按标准剂量每两周给药一次,克拉宾可以有效和安全地用于严重肾功能不全患者。
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引用次数: 0
Extra-mucosal laryngectomy for the treatment of radiation-induced non-functional larynx 粘膜外喉切除术治疗放射性非功能性喉炎
Pub Date : 2020-01-01 DOI: 10.15761/ccrr.1000489
S. Bouayed, A. Avagnina, B. Hallak
The normal human larynx has three major functions: phonation, breathing and airway protection. The voice is not essential for survival and sometimes could be compromised in an effort to preserve the airway and prevent aspiration [1]. Chronic repetitive bronchoaspiration is a serious consequence of the nonfunctional larynx, with increased morbidity and mortality. The treatment of aspiration comprises; conservative management and surgical procedures which can be divided into adjuvant and definitive procedures [2]. The adjuvant procedures include tracheotomy, cricopharyngeal myotomy [3], laryngeal suspension, cricoid resection [4] and various vocal fold medializations.
正常人的喉头有三个主要功能:发声、呼吸和气道保护。声音对生存来说并不是必不可少的,有时为了保护气道和防止误吸,声音可能会受到损害。慢性重复性支气管吸入是喉功能不全的严重后果,发病率和死亡率增高。误吸的治疗包括:保守治疗和外科手术可分为辅助治疗和最终治疗[2]。辅助手术包括气管切开术、环咽部肌切开术、喉悬吊术、环咽部切除术和各种声带中间化术。
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引用次数: 0
A case of selective straight sinus thrombosis (SST): sudden onset and evolution 选择性直窦血栓形成(SST) 1例:突然发病和演变
Pub Date : 2019-01-01 DOI: 10.26420/austinjradiol.2018.1085
Sergiacomi G, Pugliese L, C. G., Sancesario G, M. N., Floris R
Cerebral venous thrombosis, thrombosis of the intracranial veins and sinuses, is a rare type of cerebrovascular disease that hits about 0,1-0,2 people per 100000 and accounts for 0•5 % of all stroke. The mortality range from 5 to 15%. Straight sinus thrombosis is a rare type of cerebral venous sinus thromboses and is extremely difficult to diagnose, especially at its acute stage. The diagnosis is often delayed in many cases of straight sinus thrombosis that brings to treatment delay and a poor prognosis. We illustrate a case of a patient with straight sinus thrombosis with bilateral hemorrhage lesions who showed a fast evolution and sudden onset.
脑静脉血栓形成,即颅内静脉和窦的血栓形成,是一种罕见的脑血管疾病,每10万人中约有0,1-0,2人发生,占所有中风的0.5%。死亡率从5%到15%不等。直静脉窦血栓形成是一种罕见的脑静脉窦血栓形成类型,非常难以诊断,特别是在其急性期。在许多直窦血栓形成的病例中,诊断往往延迟,导致治疗延误和预后不良。我们报告一个直窦血栓形成伴双侧出血的病例,其发展迅速且发病突然。
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引用次数: 0
Preliminary result of randomized trial of an oral thrombolytic agent for deep venous thrombosis, cardiac emboli and carotid atheromatous plaques in patients with infarctive stroke: a report of three (3) cases 口服溶栓剂治疗梗死性脑卒中患者深静脉血栓、心脏栓塞和颈动脉粥样硬化斑块的随机试验初步结果:三(3)例报告
Pub Date : 2019-01-01 DOI: 10.15761/ccrr.1000457
O. Or, Awwal Am, A. Sa, Oguike We, Hassan A, Igashi Bg, Jamoh B, C. P, Ibinaiye Po, Muktar Hm, Azuh P
Thrombo-embolic conditions, particularly deep venous thrombosis, intramural cardiac thrombi and carotid atheromatous plaques require immediate medical attention because of their propensity to produce fatal pulmonary, cardiac and cerebrovascular outcomes. Treatment of these conditions are varied and sometimes complicated. In this paper, we report successful treatment of each of these three conditions using oral NattoEnzym supplement tablets, with the aim to great awareness of the effectiveness of NattoEnzym in thrombo-embolic conditions.
血栓栓塞性疾病,特别是深静脉血栓、心腔内血栓和颈动脉粥样硬化斑块,需要立即就医,因为它们容易产生致命的肺部、心脏和脑血管后果。这些疾病的治疗方法多种多样,有时还很复杂。在本文中,我们报告了使用口服纳豆酶补充片成功治疗这三种情况,目的是提高对纳豆酶在血栓栓塞条件下的有效性的认识。
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引用次数: 0
New Syndrome: Partially Ectodermal Growth Deficiency (Fidan Syndrome) 新综合征:部分外胚层生长缺陷(Fidan综合征)
Pub Date : 2019-01-01 DOI: 10.15761/ccrr.1000447
V. Fidan
Background: Ectoderm is a primary germ layer. The ectodermal dysplasias are defined as developmental defects of embryonic ectoderm. Different types were defined but there is not any case that has papillomatas on tonsils. Herein, we report two girls, one was 5-year-old and the second was fifty-five year-old diagnosed with tonsillary papillomatas. Also both have ntellectual disability, curly hair and papillomatas on interdental space . Conclusion: Multidisciplinary approach to syndromic patients is always needed. Physicians must be carefull about signs and symptoms of these patients for suitable diagnosis.
背景:外胚层是主要的胚层。外胚层发育不良是指胚胎外胚层发育缺陷。定义了不同的类型,但没有一例扁桃体上有乳头状瘤。在此,我们报告两名女孩,一名5岁,另一名55岁,被诊断为扁桃体乳头状瘤。他们都有智力障碍、卷发和牙间隙乳头状瘤。结论:多学科综合治疗综合征患者是必要的。医生必须仔细观察这些病人的体征和症状,以便作出适当的诊断。
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引用次数: 0
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Clinical case reports and reviews
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