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New-Onset Diabetes Mellitus after COVID-19: Combined Effects of SARS-CoV-2 Variants, Molecular Mimicry, and m6A RNA Methylation COVID-19 后新发糖尿病:SARS-CoV-2变体、分子模拟和m6A RNA甲基化的综合效应
Pub Date : 2024-04-14 DOI: 10.3390/covid4040032
Jorge Luis Batista-Roche, Marian Mirabent-Casals, Dahis Manzanares, Gertrud Lund, A. García‐Gasca
Post-COVID syndrome, also known as long COVID, includes a range of symptoms that persist for months or even years after initial infection such as fatigue, shortness of breath, joint pain, chest pain, muscle aches, and heart palpitations, among others. In addition, long COVID is related with new-onset diseases such as diabetes mellitus. The association between SARS-CoV-2 infections and the development of diabetes mellitus is complex and not fully understood. Therefore, the objective of this article was to summarize the state of the art in possible mechanisms involved in the development of diabetes mellitus in the post-COVID-19 era, particularly the impact of SARS-CoV-2 variants on molecular mimicry, the role of viral m6A RNA methylation, and the potential associations between these factors. A better understanding of the combinatorial effects of these mechanisms is paramount for both clinicians and researchers alike because it could help tailor more effective treatment strategies, enhance patient care, and guide future research efforts.
后 COVID 综合征又称长 COVID,包括一系列在初次感染后持续数月甚至数年的症状,如疲劳、气短、关节痛、胸痛、肌肉酸痛和心悸等。此外,长期 COVID 还与糖尿病等新发疾病有关。SARS-CoV-2 感染与糖尿病发病之间的关系错综复杂,尚未完全明了。因此,本文旨在总结后 COVID-19 时代糖尿病发病的可能机制的最新进展,特别是 SARS-CoV-2 变体对分子模拟的影响、病毒 m6A RNA 甲基化的作用以及这些因素之间的潜在关联。更好地了解这些机制的组合效应对临床医生和研究人员都至关重要,因为这有助于制定更有效的治疗策略、加强对患者的护理并指导未来的研究工作。
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引用次数: 0
A Review of Environmental Factors for an Ontology-Based Risk Analysis for Pandemic Spread 基于本体的大流行病传播风险分析环境因素综述
Pub Date : 2024-04-11 DOI: 10.3390/covid4040031
Liege Cheung, Adela S. M. Lau, K. F. Lam, P. Y. Ng
Contact tracing is a method used to control the spread of a pandemic. The objectives of this research are to conduct an empirical review and content analysis to identify the environmental factors causing the spread of the pandemic and to propose an ontology-based big data architecture to collect these factors for prediction. No research studies these factors as a whole in pandemic prediction. The research method used was an empirical study and content analysis. The keywords contact tracking, pandemic spread, fear, hygiene measures, government policy, prevention programs, pandemic programs, information disclosure, pandemic economics, and COVID-19 were used to archive studies on the pandemic spread from 2019 to 2022 in the EBSCOHost databases (e.g., Medline, ERIC, Library Information Science & Technology, etc.). The results showed that only 84 of the 588 archived studies were relevant. The risk perception of the pandemic (n = 14), hygiene behavior (n = 7), culture (n = 12), and attitudes of government policies on pandemic prevention (n = 25), education programs (n = 2), business restrictions (n = 2), technology infrastructure, and multimedia usage (n = 24) were the major environmental factors influencing public behavior of pandemic prevention. An ontology-based big data architecture is proposed to collect these factors for building the spread prediction model. The new method overcomes the limitation of traditional pandemic prediction model such as Susceptible-Exposed-Infected-Recovered (SEIR) that only uses time series to predict epidemic trend. The big data architecture allows multi-dimension data and modern AI methods to be used to train the contagion scenarios for spread prediction. It helps policymakers to plan pandemic prevention programs.
接触追踪是一种用于控制大流行病传播的方法。本研究的目标是通过实证回顾和内容分析,找出导致大流行病传播的环境因素,并提出一种基于本体的大数据架构来收集这些因素,以便进行预测。目前还没有研究将这些因素作为大流行病预测的整体进行研究。采用的研究方法是实证研究和内容分析。以接触追踪、大流行传播、恐惧、卫生措施、政府政策、预防计划、大流行计划、信息披露、大流行经济学和 COVID-19 为关键词,对 EBSCOHost 数据库(如 Medline、ERIC、图书馆信息科学与技术等)中 2019 年至 2022 年有关大流行传播的研究进行归档。结果显示,588 项存档研究中只有 84 项是相关的。大流行病的风险认知(14 项)、卫生行为(7 项)、文化(12 项)以及政府对预防大流行病政策的态度(25 项)、教育计划(2 项)、商业限制(2 项)、技术基础设施和多媒体使用(24 项)是影响公众预防大流行病行为的主要环境因素。本文提出了一种基于本体的大数据架构来收集这些因素,从而建立传播预测模型。新方法克服了传统流行病预测模型(如易感者-暴露者-感染者-康复者(SEIR))仅使用时间序列预测流行趋势的局限性。大数据架构允许使用多维数据和现代人工智能方法来训练传染情景,以进行传播预测。它有助于政策制定者规划流行病预防计划。
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引用次数: 0
Kidney and Liver Predictors of Adults Hospitalized with COVID-19 Infection 感染 COVID-19 住院成人的肾脏和肝脏预测指标
Pub Date : 2024-04-07 DOI: 10.3390/covid4040030
Mariana Boulos, Moeen Sbeit, Maamoun Basheer, Guy Ben Arie, Yuval Mirkin, Nimer Assy
SARS-CoV-2 damages not only the lungs, but also the liver and kidney. Most critically ill COVID-19 patients have liver and kidney dysfunctions. The early identification of patients with COVID-19 who will develop severe or critical disease symptoms is important for delivering proper and early treatment. This research studies the correlation of liver and kidney function indexes and COVID-19 outcomes. Electronic medical record data from 391 patients diagnosed with COVID-19 in the COVID-19 Department, Galilee Medical Center, Nahariya, Israel were collected. Epidemiological, clinical, laboratory, and imaging variables were analyzed. The liver and kidney enzyme indexes were measured upon admission and discharge. A correlation between laboratory levels and severity and mortality of COVID-19 patients was undertaken. This study included 391 COVID-19 patients, 258 mild patients and 133 severe patients. Multivariate stepwise regression analyses and discriminant analyses were used to identify and validate powerful predictors. The main outcome was death or invasive ventilation. Three factors, namely higher urea nitrogen (BUN) and IL-6, and lower albumin levels, were the most powerful predictors of mortality, and classified the results (survival vs. death) correctly in 85% of cases (diagnostic accuracy) with a sensitivity of 88% and a specificity 55%. Compared with mild patients, severe patients had lower albumin (ALB), higher alanine aminotransferase (ALT), aspartate aminotransferase (AST) and BUN (all p < 0.001). COVID-19 patients, especially severe patients, have damage to liver and kidney function. BUN, IL-6 and albumin are factors predicting mortality while fibrinogen and AST could be independent factors for predicting the severity of COVID-19.
SARS-CoV-2 不仅会损害肺部,还会损害肝脏和肾脏。大多数 COVID-19 重症患者都有肝肾功能障碍。及早发现将出现严重或危重疾病症状的 COVID-19 患者,对于及早提供适当的治疗非常重要。本研究探讨了肝肾功能指标与 COVID-19 结果的相关性。研究收集了以色列纳哈里亚加利利医疗中心 COVID-19 科确诊的 391 名 COVID-19 患者的电子病历数据。对流行病学、临床、实验室和影像学变量进行了分析。入院和出院时均测量了肝酶和肾酶指数。对 COVID-19 患者的实验室水平、严重程度和死亡率之间的相关性进行了分析。该研究包括 391 名 COVID-19 患者,其中轻度患者 258 名,重度患者 133 名。研究采用多元逐步回归分析和判别分析来确定和验证强有力的预测因素。主要结果是死亡或有创通气。尿素氮(BUN)和 IL-6 较高以及白蛋白水平较低这三个因素是预测死亡率的最有力因素,在 85% 的病例(诊断准确性)中正确地对结果(存活与死亡)进行了分类,敏感性为 88%,特异性为 55%。与轻度患者相比,重度患者的白蛋白(ALB)较低,丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)和尿素氮(BUN)较高(均 p < 0.001)。COVID-19 患者,尤其是重症患者,肝肾功能受损。BUN、IL-6 和白蛋白是预测死亡率的因素,而纤维蛋白原和 AST 则是预测 COVID-19 严重程度的独立因素。
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引用次数: 0
Insulin Adjustments for Hospitalized COVID-19 Patients on a Fixed Dexamethasone Protocol 采用地塞米松固定方案的 COVID-19 住院患者的胰岛素调整
Pub Date : 2024-03-24 DOI: 10.3390/covid4040029
Daliha Aqbal, Mariam Zakher, Sophie Nicolich-Henkin, Dajana Alku, Paula Choi, Neha Bansal, Shahidul Islam
Introduction: COVID-19, in combination with steroid treatment, is known to propagate hyperglycemia in diabetic patients. The purpose of this study was to establish a new insulin protocol for diabetic patients with COVID-19 on the dexamethasone protocol for better glycemic control. Research Design and Methods: This was a retrospective cohort study conducted at NYU Langone Long Island Hospital from 1 July 2020 to 1 July 2021. Eligible cases had to meet the following inclusion criteria: age of 18 years or greater, history of or new-onset diabetes, diagnosis of COVID-19 and receiving the 10 day dexamethasone treatment, length of stay of at least 3 days with a minimum of 48 h of glucose monitoring, and requiring basal and prandial insulin with correction during hospital stay. Data were collected using the hospital’s electronic record system. The total basal, prandial, and daily doses of insulin on the day at which glycemic control was achieved, or if glycemic control was not achieved by the discharge date, then on the completion date of the dexamethasone treatment, were collected and assessed. Results: A total of 145 patient cases were analyzed. About 46% of patients achieved glycemic control. The average insulin dose required was 0.67 (0.61–0.74) unit/kg. The mean total dose of insulin was 59 units. The mean total basal dose was 21 units. The mean total prandial dose was 38 units. The average prandial doses were higher than the basal doses for all participants. Conclusions: Diabetic patients with COVID-19 on dexamethasone should be initiated on at least 0.6–0.7 u/kg of insulin to achieve glycemic control.
简介众所周知,COVID-19 与类固醇治疗结合使用会导致糖尿病患者出现高血糖。本研究的目的是为使用地塞米松治疗 COVID-19 的糖尿病患者制定新的胰岛素方案,以更好地控制血糖。研究设计与方法:这是一项回顾性队列研究,于 2020 年 7 月 1 日至 2021 年 7 月 1 日在纽约大学朗格尼长岛医院进行。符合条件的病例必须满足以下纳入标准:年龄在18岁或以上、有糖尿病史或新发糖尿病、诊断为COVID-19并接受10天地塞米松治疗、住院时间至少3天且至少接受48小时血糖监测、住院期间需要基础胰岛素和餐前胰岛素并进行校正。数据通过医院的电子记录系统收集。收集并评估血糖得到控制当天的基础胰岛素、餐前胰岛素和每日胰岛素的总剂量,如果出院时血糖仍未得到控制,则以地塞米松治疗结束日期为准。结果共分析了 145 例患者。约 46% 的患者实现了血糖控制。所需的胰岛素平均剂量为 0.67(0.61-0.74)单位/公斤。胰岛素的平均总剂量为 59 单位。基础胰岛素的平均总剂量为 21 单位。餐前胰岛素的平均总剂量为 38 单位。所有参与者的餐前平均剂量均高于基础剂量。结论使用地塞米松的 COVID-19 糖尿病患者应开始使用至少 0.6-0.7 u/kg 的胰岛素,以达到控制血糖的目的。
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引用次数: 0
Experiences and Impacts of the COVID-19 Pandemic: A Thematic Analysis COVID-19 大流行的经验和影响:专题分析
Pub Date : 2024-03-23 DOI: 10.3390/covid4040028
Catherine T. Lowe, Cheryl M. Trask, Maliha Rafiq, L. Mackay, Nicole Letourneau, Cheuk F. Ng, Janine Keown-Gerrard, Trevor Gilbert, K. Ross
The COVID-19 pandemic prompted global public health restrictions that impacted Canadians in multiple ways. The effects of the pandemic are well examined in specific populations and in researcher-defined areas (e.g., mental health, physical activity, social connections, and financial impacts). Few studies explore the complex perspectives of adults who experienced and were impacted by the pandemic. The purpose of this study was to understand Canadian adults’ perspectives of pandemic impacts over time. Methods: A sample of 347 Canadian adults were recruited during the first six months of the COVID-19 pandemic to respond to open-ended questions about the pandemic’s impacts, administered every two weeks between April 2020 and January 2021. The responses were amalgamated into epochs, defined by dates that paralleled infection rates and public health responses in Canada. Qualitative thematic analysis identified major themes for each epoch and changes in themes over time. Results: The participants predominately reported adverse impacts of the pandemic during each epoch assessed, particularly with respect to mental health, future-oriented worry, activity restrictions, and social, and employment disruptions. Key concerns were potentially driven by changes in infection rates and public health policy changes. Conclusions: The COVID-19 pandemic impacted individuals in predominantly negative and complex ways that varied over time with public health responses. Findings from the present study may direct future pandemic responses to mitigate adverse effects to best prevent infection while preserving wellbeing.
COVID-19 大流行引发了全球公共卫生限制,对加拿大人产生了多方面的影响。大流行对特定人群和研究人员定义的领域(如心理健康、体育活动、社会关系和经济影响)的影响得到了很好的研究。很少有研究探讨经历过大流行并受到其影响的成年人的复杂观点。本研究旨在了解加拿大成年人对大流行病长期影响的看法。研究方法2020 年 4 月至 2021 年 1 月期间,每两周进行一次抽样调查,在 COVID-19 大流行的前六个月期间招募了 347 名加拿大成年人,让他们回答有关大流行影响的开放式问题。这些回答被合并成不同的时间段,这些时间段是根据加拿大的感染率和公共卫生应对措施来确定的。定性主题分析确定了每个时间段的主要主题以及主题随时间的变化。结果:参与者主要报告了大流行病在每个评估时间段内造成的不利影响,尤其是在心理健康、对未来的担忧、活动限制、社会和就业混乱等方面。感染率的变化和公共卫生政策的变化可能是主要担忧的原因。结论COVID-19 大流行对个人的影响主要是负面的、复杂的,并且随着公共卫生应对措施的变化而变化。本研究的结果可能会指导未来的大流行应对措施,以减轻不利影响,从而在保护福利的同时最好地预防感染。
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引用次数: 0
A Case Study of Consumer’s Attitudes towards Agro-Food Markets in Danube Microregion in COVID-19 Pandemic 多瑙河微型地区消费者对 COVID-19 大流行病中农业食品市场态度的案例研究
Pub Date : 2024-03-15 DOI: 10.3390/covid4030027
Dario Iljkić, Olgica Klepac, Dubravka Užar, I. Samfira, Dušan Dunđerski, Daniel Haman, Catalin Zoican, Ivana Majić, Ivana Varga
The COVID-19 pandemic affected many aspects of human life including consumer behavior. The main aim of this paper was to identify basic patterns of changes in consumer attitudes towards agri-food products under the influence of the 2020 pandemic and to better understand to what extent and what kind of food market problems appeared for the inhabitants of the Danube microregion. For this purpose, an explorative study was elaborated. Assuming that the experience of COVID-19 affected consumer attitudes and sense of food security, a hybrid survey was conducted in the Danube microregion (Croatia, Serbia and Romania) during 2022. Data collected from a total of 903 respondents were statistically analyzed in SPSS. Descriptive statistics, PCA, ANOVA and t-Test were employed. The main results have shown that although the surveyed population of the Danube microregion during the pandemic in 2020 was generally not afraid of food shortages, food was in most part available for their families and their shopping habits have not changed to a large degree, the experience of the pandemic has raised the level of awareness about some issues related to food and specifically the prices of food products. Also, three different patterns of attitude and behavior towards food and agriculture, which emerged as a result of the experience of the pandemic in 2020, were identified. These patterns also proved to be different for different segments of the population. The findings suggest the need for stronger support for the development of locally affordable food systems with the use of ICT as a coping mechanism in crises.
COVID-19 大流行影响了人类生活的许多方面,包括消费者行为。本文的主要目的是确定在 2020 年大流行病影响下消费者对农业食品的态度变化的基本模式,并更好地了解多瑙河微型地区的居民在何种程度上出现了何种食品市场问题。为此,我们开展了一项探索性研究。假定 COVID-19 的经历会影响消费者的态度和食品安全感,2022 年期间在多瑙河微型地区(克罗地 亚、塞尔维亚和罗马尼亚)开展了一项混合调查。从总共 903 名受访者那里收集的数据在 SPSS 中进行了统计分析。采用了描述性统计、PCA、方差分析和 t 检验。主要结果显示,虽然多瑙河微型地区的受访者在 2020 年大流行期间普遍不担心粮食短缺,大部分家庭都能获得粮食,他们的购物习惯也没有很大程度的改变,但大流行的经历提高了他们对一些与粮食有关的问题,特别是食品价格的认识水平。此外,由于 2020 年的大流行病经历,人们对食品和农业的态度和行为出现了三种不同的模式。事实证明,不同人群的态度和行为模式也不尽相同。研究结果表明,需要更有力地支持发展当地负担得起的粮食系统,利用信息和传播技术作为危机中的应对机制。
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引用次数: 0
Evaluating Teachers’ Workplace Climate and Anxiety Response during the COVID-19 Pandemic: The Role of Information Seeking Platforms 评估 COVID-19 大流行期间教师的工作场所氛围和焦虑反应:信息搜索平台的作用
Pub Date : 2024-03-13 DOI: 10.3390/covid4030025
M. Srem-Sai, F. Quansah, E. K. Agormedah, J. Hagan, Thomas Schack
The COVID-19 disease affected the school workplace climate for teachers and led to psychological consequences. However, it is not clear how the workplace climate affected the anxiety levels of teachers. This study assessed the connection between workplace climate and COVID-19-related anxiety among senior high school (SHS) teachers during the COVID-19 pandemic. This study further examined the moderating role of professional and social media platform use on the relationship between workplace climate and COVID-19-related anxiety among teachers. Through a cross-sectional survey design, 395 high school teachers were conveniently sampled from various schools in the Central Region of Ghana. A questionnaire was used to survey participants, and the obtained data were analysed using descriptive statistics as well as simple linear regression and moderation analyses with Hayes’ PROCESS. This study revealed a negative association between workplace climate and anxiety. The relationship between workplace climate and anxiety was contingent on social media use but not professional platform use. Therefore, the consumption of unscrutinised COVID-19-related information on social media heightened fear and anxiety among teachers, even in the midst of a safe workplace environment. An effective strategy against teachers’ COVID-19-related anxiety required the provision of accurate science-driven information about the virus. School counselling psychologists, school welfare officers, and school health coordinators are encouraged to collaborate towards designed interventions that promote a safe working environment and the mental health of teachers.
COVID-19 疾病影响了教师的学校工作场所氛围,并导致了心理后果。然而,工作场所氛围如何影响教师的焦虑水平尚不清楚。本研究评估了 COVID-19 大流行期间高中(SHS)教师的工作场所氛围与 COVID-19 相关焦虑之间的联系。本研究进一步探讨了职业和社交媒体平台的使用对工作场所氛围与教师 COVID-19 相关焦虑之间关系的调节作用。本研究采用横断面调查设计,从加纳中部地区的多所学校方便地抽取了 395 名高中教师。对参与者进行了问卷调查,并使用描述性统计、简单线性回归和 Hayes' PROCESS 的调节分析对所获得的数据进行了分析。研究结果表明,工作场所氛围与焦虑之间存在负相关。工作场所氛围与焦虑之间的关系取决于社交媒体的使用情况,但不取决于专业平台的使用情况。因此,即使在安全的工作环境中,在社交媒体上消费未经核实的 COVID-19 相关信息也会加剧教师的恐惧和焦虑。要有效消除教师与 COVID-19 相关的焦虑,就必须提供有关该病毒的准确科学信息。我们鼓励学校咨询心理学家、学校福利官员和学校卫生协调员合作设计干预措施,以促进安全的工作环境和教师的心理健康。
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引用次数: 0
Peritraumatic Distress among Chinese Canadians during the Early Lockdown Stage of the COVID-19 Pandemic: Sociodemographic and Pandemic-Related Predictors COVID-19 大流行早期封锁阶段加拿大华人的创伤性心理压力:社会人口学和大流行相关预测因素
Pub Date : 2024-03-13 DOI: 10.3390/covid4030026
Alexandra Katsiris, Kesaan Kandasamy, Lixia Yang
The current study investigates the peritraumatic distress of Chinese residents living in Canada and identifies the associated sociodemographic and pandemic-related predictors during the initial phases of the Coronavirus Disease 2019 (COVID-19) pandemic lockdown (i.e., from April 2020 to June 2020). A final sample of 457 valid participants aged 18 or older completed an online survey in which peritraumatic distress was assessed with the COVID-19 Peritraumatic Distress Index (CPDI). The results showed 32.76% of the sample was in the mild to moderate range (i.e., 28–51) and 5.03% in the severe range (i.e., 52 to higher) for peritraumatic distress. The hierarchical regression models on the continuous CPDI score identified life satisfaction as a consistent protector for the CPDI (absolute values of βs = −1.21 to −0.49, ps < 0.001). After controlling for life satisfaction, the following sociodemographic risk factors were identified: being middle-aged, being employed (relative to retired people/students), living in Ontario (rather than elsewhere), and a poor health status. Furthermore, the following pandemic-related risk factors were identified: a higher self-contraction worry, more of a COVID-19 information authenticity concern, a higher future infection rate prediction, and a higher personal health hygiene appraisal. The results of our study shed light on cognitive, experiential, behavioural, and sociodemographic factors associated with peritraumatic distress for Chinese residents living in Canada during the early outbreak stage of the pandemic.
本研究调查了居住在加拿大的中国居民的创伤性痛苦,并确定了在冠状病毒病2019(COVID-19)大流行封锁初期(即2020年4月至2020年6月)的相关社会人口学和大流行相关预测因素。457名年龄在18岁或以上的有效参与者完成了在线调查,其中使用COVID-19创伤性痛苦指数(CPDI)对创伤性痛苦进行了评估。结果显示,32.76%的样本处于轻度至中度创伤困扰范围(即 28-51),5.03%的样本处于重度创伤困扰范围(即 52 至更高)。CPDI 连续得分的分层回归模型发现,生活满意度是 CPDI 的稳定保护因子(βs 的绝对值 = -1.21 到 -0.49,ps < 0.001)。在对生活满意度进行控制后,确定了以下社会人口风险因素:中年、就业(相对于退休人员/学生)、居住在安大略省(而非其他地区)以及健康状况较差。此外,我们还发现了以下与大流行相关的风险因素:更担心自我收缩、更关注 COVID-19 信息的真实性、更高的未来感染率预测以及更高的个人健康卫生评价。我们的研究结果揭示了在大流行爆发早期阶段,与居住在加拿大的中国居民的创伤性痛苦相关的认知、经验、行为和社会人口因素。
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引用次数: 0
Pro-Vaccination Flu and COVID-19 Messages: Evidence of Congenial Targeted and Spillover Effects 支持接种流感疫苗和 COVID-19 的信息:同源性目标效应和溢出效应的证据
Pub Date : 2024-03-11 DOI: 10.3390/covid4030024
J. Dillard, Lijiang Shen
Given the plentitude of messages in the public arena that promote vaccination against different diseases or raise the possibility of vaccine mandates, we asked whether message effects in one disease domain might spill over into other domains. Our experiment exposed individuals (N = 1755) recruited from an opt-in online panel (Qualtrics) on influenza or COVID-19 pro-vaccination messages then measured intentions to vaccinate for each disease and intentions to support a vaccine mandate for each disease. Messages that targeted flu (vs. COVID-19) exhibited stronger effects on intentions to vaccinate for corresponding (vs. noncorresponding) disease. We observed positive spillover from intention to vaccinate against one disease to intention to vaccinate against the other disease, as well as from vaccination intention type to support for corresponding and noncorresponding vaccine mandates. Although pro-vaccination flu and COVID-19 messages have multiple effects, those effects are congenial. The results adjudicate differences in spillover theory and suggest synergistic effects between pro-vaccination campaigns.
鉴于公共领域中存在大量针对不同疾病的疫苗接种宣传或提出疫苗强制接种可能性的信息,我们提出了这样一个问题:一种疾病领域的信息效应是否会蔓延到其他领域。我们的实验让从选择加入的在线小组(Qualtrics)中招募的个人(N = 1755)接触流感或 COVID-19 疫苗接种宣传信息,然后测量他们对每种疾病的疫苗接种意向以及对每种疾病的疫苗接种授权的支持意向。针对流感(vs. COVID-19)的信息对相应疾病(vs. 非相应疾病)疫苗接种意愿的影响更大。我们观察到从一种疾病的疫苗接种意向到另一种疾病的疫苗接种意向的正溢出效应,以及从疫苗接种意向类型到对相应和非相应疫苗接种授权的支持的正溢出效应。尽管支持接种流感疫苗和 COVID-19 的信息具有多重效应,但这些效应是同源的。研究结果修正了溢出理论的分歧,并表明支持疫苗接种活动之间存在协同效应。
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引用次数: 0
Changes in Need, Changes in Infrastructure: A Comparative Assessment of Rural Nonprofits Responding to COVID-19 需求的变化,基础设施的变化:农村非营利组织应对 COVID-19 的比较评估
Pub Date : 2024-03-10 DOI: 10.3390/covid4030023
Margaret F. Sloan, Tina Switzer, L. Trull, Claire Switzer, Melody Eaton, Kelly Atwood, Emily Akerson
Due to the variance in community infrastructure and resources, COVID-19 impacted rural communities differently than their urban counterparts. This study examines two waves of data from a survey of rural residents in the Shenandoah Valley of Virginia regarding how community organizations responded to the pandemic, what strategies were most successful, and where needs shifted. The findings demonstrate that organizations with deeply embedded community leaders achieve higher levels of collaborative change in a timely manner. Additionally, mental health services have become a more pronounced need as a result of the pandemic. The interdependence of community needs, recognized by community members, calls for collaborative strategies for the future.
由于社区基础设施和资源的差异,COVID-19 对农村社区的影响不同于城市社区。本研究通过对弗吉尼亚州谢南多河谷的农村居民进行调查,研究了两波数据,内容涉及社区组织如何应对大流行病、哪些策略最为成功以及哪些方面的需求发生了变化。调查结果表明,社区领袖深入社区的组织能够及时实现更高水平的合作变革。此外,由于大流行病的影响,心理健康服务已成为一个更为突出的需求。社区成员认识到社区需求之间的相互依存性,这就要求在未来采取合作战略。
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引用次数: 0
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