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Relationship between BMI and COVID-19 体重指数与 COVID-19 的关系
Pub Date : 2023-11-19 DOI: 10.3390/covid3110117
Patrícia Coelho, Manuel Martins, Catarina Gavinhos, Joana Liberal, Ema Cabral, Inês Ribeiro, Francisco Rodrigues
Body mass index has been studied as one of the factors that negatively influences COVID-19. In this work, we intend to analyze this influence. A representative sample of the population of Beira Interior was used (around 2%), on which immunity research and a socio-demographic survey were carried out. It was found that obesity influences the vaccination rate, and that all other variables analyzed were not influenced by body mass index.
体重指数是对 COVID-19 产生负面影响的因素之一。在这项工作中,我们打算分析这种影响。我们使用了贝拉内陆地区具有代表性的人口样本(约 2%),对其进行了免疫研究和社会人口调查。结果发现,肥胖会影响疫苗接种率,而所有其他分析变量均不受体重指数的影响。
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引用次数: 0
Service Uptake Challenges Experienced by Pasifika Communities during COVID-19 Lockdowns in New Zealand 新西兰新冠肺炎封锁期间,帕西菲卡社区面临的服务接受挑战
Pub Date : 2023-11-10 DOI: 10.3390/covid3110116
Vili Nosa, John Sluyter, Atefeh Kiadarbandsari, Malakai Ofanoa, Maryann Heather, Fuafiva Fa’alau, Ravi Reddy
Background: New Zealand was one of the first countries to adopt an elimination strategy based on a four-tier Alert Level system that included strict lockdowns at levels three and four. The lockdowns meant shutting out external social networks and being confining to individual household ‘bubbles’ only. This presented challenges for minority Pasifika communities in New Zealand as their cultural values are based on social bonding, interconnectedness, community engagement and caring for each other. The aim of this research was to conduct a small-scale pilot study to test and refine the study design and identify the major challenges faced by Pasifika communities in relation to accessing health, social and mental services while in lockdown. Methods: This exploratory study was designed using an online anonymous questionnaire survey targeting people who identified as Pasifika. A total of eighty-seven respondents were included in our analyses following the questionnaire survey. Results: Five main barriers to accessing health, social and mental health services during lockdowns were identified; (1) unavailability of or limited services; (2) fear of contracting the virus; (3) perception of high costs associated with seeking medical assistance; (4) transportation difficulties; and (5) lack of time. Almost a quarter of the respondents reported losing their jobs, 80% indicated a decline in their household income and more than half experienced some form of psychosocial distress while in lockdown. Conclusions: The findings of this research highlight existing challenges faced by Pasifika communities in adequately accessing essential services. Future research can focus on the key barriers to access identified in this research to gain a deeper understanding of services and its interaction with Pasifika communities during lockdowns.
背景:新西兰是首批采用基于四级警戒级别系统的消除战略的国家之一,其中包括三级和四级的严格封锁。封锁意味着关闭外部社交网络,只局限于单个家庭的“泡沫”。这给新西兰的少数民族帕西菲卡社区带来了挑战,因为他们的文化价值观是基于社会联系、相互联系、社区参与和相互关心。这项研究的目的是进行一项小规模试点研究,以测试和完善研究设计,并确定Pasifika社区在封锁期间获得保健、社会和精神服务方面面临的主要挑战。方法:本探索性研究采用在线匿名问卷调查设计,调查对象为帕西菲卡人。问卷调查后,共有87名受访者参与了我们的分析。结果:确定了封锁期间获得卫生、社会和精神卫生服务的五大障碍;(1)服务不可用或有限;(2)害怕感染病毒;(3)对就医费用过高的认知;(四)运输困难;(5)缺乏时间。近四分之一的受访者表示失去了工作,80%的人表示他们的家庭收入下降,超过一半的人在封锁期间经历了某种形式的心理社会困扰。结论:本研究的结果突出了Pasifika社区在充分获得基本服务方面面临的现有挑战。未来的研究可以将重点放在本研究确定的主要访问障碍上,以更深入地了解服务及其在封锁期间与帕西菲卡社区的互动。
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引用次数: 0
The Impact of the COVID-19 Pandemic in the Netherlands on Primary Healthcare Use and Clinical Outcomes in Persons with Type 2 Diabetes 荷兰COVID-19大流行对2型糖尿病患者初级卫生保健使用和临床结果的影响
Pub Date : 2023-11-03 DOI: 10.3390/covid3110115
Jesse M. van den Berg, Marieke T. Blom, Karin M. A. Swart, Jetty A. Overbeek, S. Remmelzwaal, Petra J. M. Elders, Ron M. C. Herings
The COVID-19 pandemic has had a significant impact on healthcare systems worldwide, including the postponing or canceling of appointments and procedures for type 2 diabetes (T2D) care by general practitioners (GPs) in the Netherlands. The aim of this study was to investigate the impact of the COVID-19 pandemic on primary healthcare use and clinical measurements for people with T2D. Additionally, we aimed to determine if changes were observed among specific risk groups: (1) persons 70 years or older, or below 70 years, (2) patients who were meeting their HbA1c targets and those who were not, and (3) patients with high-risk and non-high-risk T2D. This retrospective cohort study among persons with T2D was conducted using data from the DIAbetes MANagement and Treatment (DIAMANT) data infrastructure, deriving data from electronic medical records of Dutch GPs. The study assessed GP visit counts, and counts and values of clinical measurements, including hemoglobin A1c (HbA1c), body mass index (BMI), low-density lipoprotein (LDL) cholesterol, and systolic blood pressure (SBP). Adjusted negative binomial (NB) regression and generalized estimating equations (GEE) models were used to estimate GP visit counts and population averages of clinical measurements, respectively, comparing 2019 (pre-pandemic) with 2020 (during the pandemic). Changes in specific groups were examined by stratifying outcomes for the aforementioned subgroups. The cohort consisted of 182,048 patients with T2D (47% female, mean age 69 ± 13 years) on 1 March 2019, of which 168,097 persons (92%) still contributed follow-up data in 2020. We observed an increase in total GP visits in 2020, with an adjusted rate ratio (RR) of 1.09 (95% CI 1.08–1.09). The frequency increased for office visits (RR 1.06; 1.06–1.07) and phone calls (RR 1.33; 1.31–1.35) but remained stable for home visits (RR 1.02; 0.99–1.04). On both population and individual levels, HbA1c values increased in 2020 by 1.65 (1.59–1.70) mmol/mol compared to 2019. Observed changes in 2020 for BMI, LDL, and SBP values were also statistically significant but small. Subgroup stratifications showed higher scores of all clinical measurements in younger persons (<70 years), those who met their HbA1c target, and non-high-risk T2D patients than their respective high-risk subgroups. During the first year of the COVID-19 pandemic in the Netherlands, changes in primary healthcare use were observed among persons with T2D, with an increase in GP office visits and phone calls and a decreased number of clinical measurements and GP home visits. HbA1c levels increased among patients with T2D in 2020. Further research is necessary to determine the impact of the COVID-19 pandemic on long-term clinical outcomes and (long-term) T2D complications.
2019冠状病毒病大流行对全球卫生保健系统产生了重大影响,包括推迟或取消荷兰全科医生对2型糖尿病(T2D)的预约和治疗程序。本研究的目的是调查COVID-19大流行对T2D患者初级卫生保健使用和临床测量的影响。此外,我们的目的是确定在特定风险组中是否观察到变化:(1)70岁或以上或70岁以下的人,(2)达到HbA1c目标的患者和未达到目标的患者,(3)高风险和非高风险T2D患者。这项t2dm患者的回顾性队列研究使用糖尿病管理和治疗(DIAMANT)数据基础设施的数据进行,数据来源于荷兰全科医生的电子医疗记录。该研究评估了全科医生就诊计数,以及临床测量的计数和值,包括血红蛋白A1c (HbA1c)、体重指数(BMI)、低密度脂蛋白(LDL)胆固醇和收缩压(SBP)。采用调整后的负二项回归(NB)和广义估计方程(GEE)模型,分别对2019年(大流行前)和2020年(大流行期间)的全科医生就诊次数和临床测量的人口平均值进行了估计。通过上述亚组的分层结果来检查特定组的变化。该队列包括2019年3月1日的182,048例T2D患者(47%为女性,平均年龄69±13岁),其中168,097人(92%)在2020年仍提供随访数据。我们观察到2020年全科医生总就诊人数增加,调整后的比率(RR)为1.09 (95% CI 1.08-1.09)。就诊频率增加(RR 1.06;1.06-1.07)和电话(RR 1.33;1.31-1.35),但家访保持稳定(RR 1.02;0.99 - -1.04)。在群体和个体水平上,2020年的HbA1c值比2019年增加了1.65 (1.59-1.70)mmol/mol。观察到2020年BMI、LDL和收缩压值的变化也有统计学意义,但很小。亚组分层显示,与各自的高风险亚组相比,年轻人(70岁)、达到HbA1c目标的患者和非高风险T2D患者的所有临床测量得分更高。在荷兰COVID-19大流行的第一年,观察到t2dm患者的初级卫生保健使用情况发生了变化,全科医生办公室就诊和电话次数增加,临床测量和全科医生家访次数减少。2020年,T2D患者的HbA1c水平升高。需要进一步研究确定COVID-19大流行对长期临床结果和(长期)T2D并发症的影响。
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引用次数: 0
Prevalence of Post COVID-19 Condition among Healthcare Workers: Self-Reported Online Survey in Four African Countries, December 2021–January 2022 2021年12月至2022年1月,四个非洲国家医护人员中COVID-19后状况的患病率:自我报告的在线调查
Pub Date : 2023-10-30 DOI: 10.3390/covid3110114
Hager Elnadi, Ahmad I. Al-Mustapha, Ismail A. Odetokun, AbdulAzeez Adeyemi Anjorin, Rasha Mosbah, Folorunso O. Fasina, Youssef Razouqi, Kwame Sherrif Awiagah, Jean Baptiste Nyandwi, Zuhal E. Mhgoob, George Gachara, Mohamed Farah Yusuf Mohamud, Bamu F. Damaris, Aala Mohamed Osman Maisara, Mona Radwan
The impact of Post COVID-19 Condition (PCC) is ongoing despite the declaration that the 2019 COVID-19 pandemic has ended. In this study, we explore the prevalence of PCC among healthcare workers (HCWs) in four African Countries and its influence on their professional performance. This study was conducted as an online cross-sectional survey of healthcare workers from four African countries (Cameroon, Egypt, Nigeria, and Somalia) between the 20th of December 2021 to 12th of January 2022. We determined the prevalence of PCC based on the WHO case definition and assessed variables associated with a higher prevalence of PCC in these countries using univariable and multivariable logistic regression analyses. A total of 706 HCWs from four African countries were included in this survey. Most of the HCWs were aged between 18–34 years (75.8%, n = 535). Our findings showed that 19.5% (n = 138) of the HCWs had tested positive for SARS-CoV-2. However, 8.4% (n = 59) were symptomatic for COVID-19 but tested negative or were never tested. Two-thirds of the HCWs (66.4%, n = 469) have received a COVID-19 vaccine and 80.6% (n = 378) of those vaccinated had been fully vaccinated. The self-reported awareness rate of PCC among the HCWs was 16.1% (n = 114/706) whereas the awareness rate of PCC among COVID-19-positive HCWs was 55.3% (n = 109/197). The prevalence of PCC among HCWs was 58.8% (n = 116). These changes include the self-reported symptoms of PCC which included headache (58.4%, n = 115), fatigue (58.8%, n = 116), and muscle pain (39.6%, n = 78). Similarly, 30% (n = 59) and 20.8% (n = 41) of the HCWs reported the loss of smell and loss of taste long after their COVID-19 infection, respectively. Some HCWs (42%, n = 83) believed that their work performance has been affected by their ongoing symptoms of PCC. There was no significant difference in the prevalence of PCC among the vaccinated and unvaccinated HCWs (p > 0.05). Of the socio-demographic variables, age (older HCWs between 45–54 years; OR:1.7; 95% CI: 1.06, 10.59; p = 0.001) and location (Egypt; OR:14.57; 95% CI: 2.62, 26.76; p = 0.001) were more likely to have experienced PCC than other age groups and countries respectively. The study revealed a low prevalence of PCC among the surveyed HCWs. In addition, it observed the need for adequate medical and psychological support to HCWs with PCC and improved mass advocacy campaigns on PCC.
尽管宣布2019年COVID-19大流行已经结束,但COVID-19后状态(PCC)的影响仍在继续。在本研究中,我们探讨了四个非洲国家卫生保健工作者(HCWs)中PCC的患病率及其对其专业绩效的影响。本研究是在2021年12月20日至2022年1月12日期间对来自四个非洲国家(喀麦隆、埃及、尼日利亚和索马里)的卫生保健工作者进行的在线横断面调查。我们根据世卫组织病例定义确定了PCC的患病率,并使用单变量和多变量logistic回归分析评估了与这些国家PCC较高患病率相关的变量。这项调查共包括来自四个非洲国家的706名卫生保健员。大多数健康护理人员年龄在18-34岁之间(75.8%,n = 535)。我们的研究结果显示,19.5% (n = 138)的卫生工作者检测出SARS-CoV-2阳性。然而,8.4% (n = 59)有COVID-19症状,但检测呈阴性或从未检测过。三分之二(66.4%,n = 469)的卫生保健工作者接种了新冠病毒疫苗,80.6% (n = 378)的卫生保健工作者接种了完全疫苗。自报PCC知晓率为16.1% (n = 114/706),阳性医护人员PCC知晓率为55.3% (n = 109/197)。医护人员中PCC患病率为58.8% (n = 116)。这些变化包括自我报告的PCC症状,包括头痛(58.4%,n = 115)、疲劳(58.8%,n = 116)和肌肉疼痛(39.6%,n = 78)。同样,30% (n = 59)和20.8% (n = 41)的卫生保健工作者分别报告在感染COVID-19后很长时间内嗅觉和味觉丧失。一些医护人员(42%,n = 83)认为他们的工作表现受到了持续的PCC症状的影响。接种疫苗和未接种疫苗的卫生保健工作者的PCC患病率无显著差异(p >0.05)。在社会人口学变量中,年龄(45-54岁之间的老年卫生保健员;OR: 1.7;95% ci: 1.06, 10.59;p = 0.001)和地理位置(埃及;OR: 14.57;95% ci: 2.62, 26.76;p = 0.001)分别比其他年龄组和国家更容易经历PCC。研究显示,在接受调查的卫生保健工作者中,PCC的患病率较低。此外,委员会注意到,有必要向患有艾滋病的卫生保健工作者提供充分的医疗和心理支持,并改进关于艾滋病的群众宣传运动。
{"title":"Prevalence of Post COVID-19 Condition among Healthcare Workers: Self-Reported Online Survey in Four African Countries, December 2021–January 2022","authors":"Hager Elnadi, Ahmad I. Al-Mustapha, Ismail A. Odetokun, AbdulAzeez Adeyemi Anjorin, Rasha Mosbah, Folorunso O. Fasina, Youssef Razouqi, Kwame Sherrif Awiagah, Jean Baptiste Nyandwi, Zuhal E. Mhgoob, George Gachara, Mohamed Farah Yusuf Mohamud, Bamu F. Damaris, Aala Mohamed Osman Maisara, Mona Radwan","doi":"10.3390/covid3110114","DOIUrl":"https://doi.org/10.3390/covid3110114","url":null,"abstract":"The impact of Post COVID-19 Condition (PCC) is ongoing despite the declaration that the 2019 COVID-19 pandemic has ended. In this study, we explore the prevalence of PCC among healthcare workers (HCWs) in four African Countries and its influence on their professional performance. This study was conducted as an online cross-sectional survey of healthcare workers from four African countries (Cameroon, Egypt, Nigeria, and Somalia) between the 20th of December 2021 to 12th of January 2022. We determined the prevalence of PCC based on the WHO case definition and assessed variables associated with a higher prevalence of PCC in these countries using univariable and multivariable logistic regression analyses. A total of 706 HCWs from four African countries were included in this survey. Most of the HCWs were aged between 18–34 years (75.8%, n = 535). Our findings showed that 19.5% (n = 138) of the HCWs had tested positive for SARS-CoV-2. However, 8.4% (n = 59) were symptomatic for COVID-19 but tested negative or were never tested. Two-thirds of the HCWs (66.4%, n = 469) have received a COVID-19 vaccine and 80.6% (n = 378) of those vaccinated had been fully vaccinated. The self-reported awareness rate of PCC among the HCWs was 16.1% (n = 114/706) whereas the awareness rate of PCC among COVID-19-positive HCWs was 55.3% (n = 109/197). The prevalence of PCC among HCWs was 58.8% (n = 116). These changes include the self-reported symptoms of PCC which included headache (58.4%, n = 115), fatigue (58.8%, n = 116), and muscle pain (39.6%, n = 78). Similarly, 30% (n = 59) and 20.8% (n = 41) of the HCWs reported the loss of smell and loss of taste long after their COVID-19 infection, respectively. Some HCWs (42%, n = 83) believed that their work performance has been affected by their ongoing symptoms of PCC. There was no significant difference in the prevalence of PCC among the vaccinated and unvaccinated HCWs (p &gt; 0.05). Of the socio-demographic variables, age (older HCWs between 45–54 years; OR:1.7; 95% CI: 1.06, 10.59; p = 0.001) and location (Egypt; OR:14.57; 95% CI: 2.62, 26.76; p = 0.001) were more likely to have experienced PCC than other age groups and countries respectively. The study revealed a low prevalence of PCC among the surveyed HCWs. In addition, it observed the need for adequate medical and psychological support to HCWs with PCC and improved mass advocacy campaigns on PCC.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136022905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transmission of COVID-19 in Cities with Weather Conditions of High Air Humidity: Lessons Learned from Turkish Black Sea Region to Face Next Pandemic Crisis 高空气湿度天气条件下城市中COVID-19的传播:从土耳其黑海地区吸取的经验教训,以应对下一次大流行危机
Pub Date : 2023-10-29 DOI: 10.3390/covid3110113
Aytac Perihan Akan, Mario Coccia
The goal of this study is to analyze associations between COVID-19 transmission and meteorological indicators in cities of the Black Sea region of Turkey, located specifically in the dampest area, with excess rainfall and recurring fog. In particular, the working hypothesis is that the widespread transmission of new coronavirus SARS-CoV-2 (leading to the airborne disease COVID-19) in cities can be explained by specific weather conditions, namely high levels of air humidity. Statistical evidence here does not seem, in general, to support the hypothesis that the accelerated transmission of COVID-19 in the studied cities can be explained by high levels of humidity because different meteorological, environmental, demographic, and socioeconomic factors also plays a critical role in the disease transmission dynamics of the investigated region. The main implications of our findings here are that the demographic structure of the population, climate indicators, organization of the health system, and environmental factors (e.g., air pollution, etc.) should be considered through a systemic approach when designing effective national and regional pandemic plans directed to implement health policies for facing new variants of COVID-19 and/or new airborne diseases, in order to reduce their negative effects on health, social and economic systems.
本研究的目的是分析土耳其黑海地区城市的COVID-19传播与气象指标之间的关系,特别是在最潮湿的地区,降雨量过多,雾反复出现。具体来说,工作假设是,新型冠状病毒SARS-CoV-2(导致空气传播疾病COVID-19)在城市的广泛传播可以用特定的天气条件,即高空气湿度来解释。总体而言,这里的统计证据似乎并不支持这样的假设,即所研究城市的COVID-19加速传播可以用高湿度来解释,因为不同的气象、环境、人口和社会经济因素在被调查地区的疾病传播动态中也起着关键作用。我们的研究结果的主要含义是,在设计有效的国家和区域大流行计划时,应通过系统的方法考虑人口结构、气候指标、卫生系统组织和环境因素(例如空气污染等),这些计划旨在实施卫生政策,以应对COVID-19的新变种和/或新的空气传播疾病,以减少它们对健康的负面影响。社会和经济制度。
{"title":"Transmission of COVID-19 in Cities with Weather Conditions of High Air Humidity: Lessons Learned from Turkish Black Sea Region to Face Next Pandemic Crisis","authors":"Aytac Perihan Akan, Mario Coccia","doi":"10.3390/covid3110113","DOIUrl":"https://doi.org/10.3390/covid3110113","url":null,"abstract":"The goal of this study is to analyze associations between COVID-19 transmission and meteorological indicators in cities of the Black Sea region of Turkey, located specifically in the dampest area, with excess rainfall and recurring fog. In particular, the working hypothesis is that the widespread transmission of new coronavirus SARS-CoV-2 (leading to the airborne disease COVID-19) in cities can be explained by specific weather conditions, namely high levels of air humidity. Statistical evidence here does not seem, in general, to support the hypothesis that the accelerated transmission of COVID-19 in the studied cities can be explained by high levels of humidity because different meteorological, environmental, demographic, and socioeconomic factors also plays a critical role in the disease transmission dynamics of the investigated region. The main implications of our findings here are that the demographic structure of the population, climate indicators, organization of the health system, and environmental factors (e.g., air pollution, etc.) should be considered through a systemic approach when designing effective national and regional pandemic plans directed to implement health policies for facing new variants of COVID-19 and/or new airborne diseases, in order to reduce their negative effects on health, social and economic systems.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"37 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136134960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of CoronaVac and CoviShield Vaccines on SARS-CoV-2 Infection in Healthcare Workers in Salvador, Brazil CoronaVac和CoviShield疫苗对巴西萨尔瓦多医护人员SARS-CoV-2感染的评估
Pub Date : 2023-10-27 DOI: 10.3390/covid3110112
Jesús Enrique Patiño Escarcina, Felipe de Jesus Souza, Ana Keila Carvalho Vieira Da Silva, Keile Kemyly Assis Da Silva, Ruan Barbosa Souza, Saulo Reis Nery Santos, Eduardo M. Netto
The emergence and rapid spread of the SARS-CoV-2 Gamma variant in Brazil have raised concerns about SARS-CoV-2 vaccines’ neutralizing capacity and viral load impact. Our study aimed to assess the influence of the CoviShield and CoronaVac vaccines on the Ct-N2 value in the healthcare organization’s staff who experienced primary SARS-CoV-2 infection. We examined sixty-three COVID-19 cases reported in the first half of 2021 and identified similar clinical and laboratory characteristics among individuals, regardless of the vaccine they received. Surprisingly, our observations revealed that both CoviShield and CoronaVac vaccines had no impact on viral load or the development and severity of symptoms. These findings suggest a potential reduction in neutralizing response and indicate the need to consider the incorporation of other SARS-CoV-2 vaccines and maintain additional containment measures against SARS-CoV-2, as they remain imperative despite vaccination efforts.
SARS-CoV-2 γ变体在巴西的出现和迅速传播引发了人们对SARS-CoV-2疫苗的中和能力和病毒载量影响的担忧。本研究旨在评估CoviShield和CoronaVac疫苗对医疗机构中经历过原发性SARS-CoV-2感染的工作人员Ct-N2值的影响。我们检查了2021年上半年报告的63例COVID-19病例,并确定了个体之间相似的临床和实验室特征,无论他们接种了何种疫苗。令人惊讶的是,我们的观察显示,CoviShield和CoronaVac疫苗对病毒载量或症状的发展和严重程度没有影响。这些发现表明,中和反应可能会减少,并表明有必要考虑合并其他SARS-CoV-2疫苗,并保持针对SARS-CoV-2的额外遏制措施,因为尽管努力接种疫苗,这些措施仍然是必要的。
{"title":"Evaluation of CoronaVac and CoviShield Vaccines on SARS-CoV-2 Infection in Healthcare Workers in Salvador, Brazil","authors":"Jesús Enrique Patiño Escarcina, Felipe de Jesus Souza, Ana Keila Carvalho Vieira Da Silva, Keile Kemyly Assis Da Silva, Ruan Barbosa Souza, Saulo Reis Nery Santos, Eduardo M. Netto","doi":"10.3390/covid3110112","DOIUrl":"https://doi.org/10.3390/covid3110112","url":null,"abstract":"The emergence and rapid spread of the SARS-CoV-2 Gamma variant in Brazil have raised concerns about SARS-CoV-2 vaccines’ neutralizing capacity and viral load impact. Our study aimed to assess the influence of the CoviShield and CoronaVac vaccines on the Ct-N2 value in the healthcare organization’s staff who experienced primary SARS-CoV-2 infection. We examined sixty-three COVID-19 cases reported in the first half of 2021 and identified similar clinical and laboratory characteristics among individuals, regardless of the vaccine they received. Surprisingly, our observations revealed that both CoviShield and CoronaVac vaccines had no impact on viral load or the development and severity of symptoms. These findings suggest a potential reduction in neutralizing response and indicate the need to consider the incorporation of other SARS-CoV-2 vaccines and maintain additional containment measures against SARS-CoV-2, as they remain imperative despite vaccination efforts.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"212 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136317410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Qualitative Analysis of Older Adults’ Cognitive Appraisal in Coping during the COVID-19 Pandemic: The Role of Social Capital 新冠肺炎大流行期间老年人应对认知评价的定性分析:社会资本的作用
Pub Date : 2023-10-19 DOI: 10.3390/covid3100111
Linying Dong, Alexandra Katsiris, Mariah Lecompte, Cassandra Skrotzki, Lixia Yang
The ability to adaptively cope with the challenges of stressful events such as the COVID-19 pandemic is crucial for healthy aging. One effective coping strategy is social coping in which social networks are tapped for support. However, our review of the current literature on older adults’ coping abilities reveals two shortcomings: (1) a lack of consideration of a specific context and (2) an inadequate amount of attention paid to the different types of social networks in the cognitive appraisal process. As coping is a process in which older adults undergo the cognitive appraisal process to identify appropriate coping strategies, the shortcomings result in an incomplete understanding of older adults’ coping efforts and impair the development of effective community and intervention programs to improve older adults’ well-being. To fill this gap, drawing on the Transactional Model of Stress and Coping and the Social Capital Theory, we conducted 22 interviews with older adults who experienced lockdown measures during COVID-19. Our in-depth qualitative analysis shows the different roles played by bonding and bridging social capital in the cognitive appraisal process and illustrates the influence of a specific context on cognitive appraisals and subsequent coping efforts. Our findings provide significant contributions to theories regarding coping and social capital, as well as practices and policies for improving the well-being of older adults.
适应性应对COVID-19大流行等压力事件挑战的能力对于健康老龄化至关重要。一种有效的应对策略是利用社会网络来寻求支持的社会应对。然而,我们回顾了目前关于老年人应对能力的文献,发现了两个不足之处:(1)缺乏对特定情境的考虑;(2)在认知评估过程中对不同类型的社会网络的关注不足。由于老年人的应对是一个认知评估过程,在这个过程中,老年人通过认知评估来确定适当的应对策略,这些缺陷导致了对老年人应对努力的不完全理解,并影响了有效的社区和干预计划的发展,以改善老年人的福祉。为了填补这一空白,我们利用压力与应对的交易模型和社会资本理论,对在COVID-19期间经历过封锁措施的老年人进行了22次采访。我们深入的定性分析表明,在认知评估过程中,社会资本的结合和桥接发挥了不同的作用,并说明了特定背景对认知评估和随后的应对努力的影响。我们的研究结果对应对和社会资本的理论,以及改善老年人福祉的实践和政策都有重要的贡献。
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引用次数: 0
Housing Status and COVID-19 Prevention Recommendations among People Who Use Drugs 吸毒者的住房状况和COVID-19预防建议
Pub Date : 2023-10-17 DOI: 10.3390/covid3100110
Izza Zaidi, Ashly E. Jordan, Lauren Jessell, Leonardo Dominguez Gomez, Alex Harocopos, Michelle Nolan
Housing conditions can increase health risks for people who use opioids (PWUO). Little research documents the influence of housing on PWUO’s ability to practice disease prevention methods. This study examines associations between housing status of PWUO in NYC and their ability to practice COVID-19 prevention recommendations during the initial wave of the pandemic. Participants were recruited via convenience sampling and administered a survey. Eligibility required age ≥18 years, using opioids ≥3times in the prior 30 days, and accessing a health-related service in the prior year. Descriptive and bivariate statistics assessed relationships between housing and the ability to practice social distancing, access soap and running water or hand sanitizer (soap), and access face masks. Multivariable Poisson regression was used to examine relationships between housing and the potential to practice COVID-19 prevention recommendations. The 329 participants were grouped into stable housing (34.3%), unstable/shelter housing (31.9%), and street homeless (33.7%) categories. Street homeless PWUO were significantly less likely to have access to soap and face masks than those stably housed. There were no significant differences between PWUO experiencing unstable and stable housing. PWUO experiencing street homelessness may have had increased vulnerability to COVID-19. Providing low-threshold health-related resources and increasing linkages to housing opportunities could promote health of PWUO experiencing street homelessness during future emergencies.
住房条件会增加阿片类药物使用者的健康风险。很少有研究记录住房对PWUO实践疾病预防方法的能力的影响。本研究调查了纽约市PWUO的住房状况与他们在大流行初期实施COVID-19预防建议的能力之间的关系。通过方便抽样的方式招募参与者并进行调查。资格要求年龄≥18岁,在过去30天内使用阿片类药物≥3次,并在前一年获得与健康相关的服务。描述性和双变量统计评估了住房与保持社会距离、获得肥皂和自来水或洗手液(肥皂)以及获得口罩的能力之间的关系。使用多变量泊松回归来检验住房与实施COVID-19预防建议的可能性之间的关系。329名参与者被分为稳定住房(34.3%)、不稳定/庇护住房(31.9%)和街头无家可归者(33.7%)三类。街头无家可归的PWUO比那些稳定居住的人更不可能获得肥皂和口罩。经历不稳定和稳定住房的PWUO之间没有显著差异。街头无家可归的PWUO可能更容易感染COVID-19。提供低门槛的健康相关资源并增加与住房机会的联系,可促进在未来紧急情况下街头无家可归的PWUO的健康。
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引用次数: 0
Changes in Lifestyle Habits in Individuals with Diabetes during the COVID-19 Pandemic: The ELSA-Brasil Cohort Study COVID-19大流行期间糖尿病患者生活习惯的变化:elsa -巴西队列研究
Pub Date : 2023-10-12 DOI: 10.3390/covid3100109
William Jones Dartora, Maria Inês Schmidt, Rosane Harter Griep, Bruce B. Duncan
The COVID-19 pandemic and society’s response to it may have constrained the ability of those with diabetes to achieve a healthy lifestyle. We conducted a longitudinal study to assess the frequency and magnitude of sedentary habits, physical activity, sleep, alcohol consumption, weight, and smoking from July 2020 to February 2021 and compared these levels to those before the pandemic (2017–2019) in 1082 participants of the ELSA-Brasil study with known diabetes. Our results showed that inappropriate sleep duration was common (649, 68.9%) before the pandemic. Many (447, 31.1%) with this problem achieved an adequate sleep duration during the pandemic. Significant increases occurred in time in front of screens (1.3; 95%CI 0.66–2.11 h/day) and time sitting or reclining (1.4, 95%CI 0.8–2.3 h/day). Physical activity decreased (270, 95%CI 243–298 MET-min/wk). Alcohol consumption decreased without statistical significance (−19.6, 95%CI −51.1–11.9 g/w). In general, changes were similar between diabetics and non-diabetics, except that screen time in-creased less (−0.18, −0.35–−0.01 h/day) for those with diabetes. Sleep duration improved, but the frequency of sedentary habits increased, and physical activity decreased during the pandemic. Understanding changes brought on by the pandemic is essential to facilitate the implementation of quality health care for those with diabetes in moments of social stress.
2019冠状病毒病大流行和社会对此的反应可能限制了糖尿病患者实现健康生活方式的能力。我们进行了一项纵向研究,以评估2020年7月至2021年2月期间久坐习惯、身体活动、睡眠、饮酒、体重和吸烟的频率和程度,并将这些水平与已知糖尿病的1082名elsa - brazil研究参与者在大流行(2017-2019)之前的水平进行比较。我们的结果显示,在大流行之前,睡眠时间不适当很常见(649人,68.9%)。有这一问题的许多人(447人,31.1%)在大流行期间获得了充足的睡眠时间。在屏幕前的时间显著增加(1.3;95%CI 0.66-2.11 h/天)和坐下或躺卧时间(1.4,95%CI 0.8-2.3 h/天)。体力活动减少(270%,95%可信区间为243-298 MET-min/周)。酒精摄入量下降,但无统计学意义(- 19.6,95%CI - 51.1-11.9 g/w)。总的来说,糖尿病患者和非糖尿病患者之间的变化相似,除了糖尿病患者的屏幕时间增加较少(- 0.18小时/天,- 0.35 - - 0.01小时/天)。大流行期间,睡眠时间有所改善,但久坐习惯的频率增加,身体活动减少。了解大流行带来的变化对于促进在社会压力时刻为糖尿病患者提供高质量卫生保健至关重要。
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引用次数: 0
SARS-CoV-2: An Update on the Biological Interplay with the Human Host SARS-CoV-2:与人类宿主生物相互作用的最新进展
Pub Date : 2023-10-10 DOI: 10.3390/covid3100108
Giuseppe Lippi, Fabian Sanchis-Gomar, Camilla Mattiuzzi, Brandon M. Henry
Coronavirus Disease 2019 (COVID-19) is an infectious respiratory illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease, first identified in the Chinese city of Wuhan in November 2019, has since spread worldwide, is the latest human pandemic and has officially infected over 800 million people and has caused nearly seven million deaths to date. Although SARS-CoV-2 belongs to the large family of coronaviruses, it has some unique biological characteristics in its interplay with the human host. Therefore, this narrative review aims to provide an up-to-date overview of the structure of the virus, incubation and shedding in the human host, infectivity and biological evolution over time, as well as the main mechanisms for invading human host cells and replicating within. We also proffer that ongoing epidemiological surveillance of newly emerged variants must always be accompanied by biological studies aimed at deciphering new advantageous traits that may contribute to increasing virulence and pathogenicity, such that the most appropriate strategies for establishing a (relatively) safe coexistence with the human host can be implemented.
冠状病毒病2019 (COVID-19)是由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的一种传染性呼吸道疾病。该疾病于2019年11月在中国武汉市首次发现,此后已在全球蔓延,是最新的人类大流行,迄今已正式感染8亿多人,造成近700万人死亡。虽然SARS-CoV-2属于冠状病毒大家族,但它在与人类宿主的相互作用中具有一些独特的生物学特性。因此,本综述旨在对病毒的结构、在人类宿主中的孵化和脱落、传染性和随时间的生物进化,以及入侵人类宿主细胞和在体内复制的主要机制提供最新的概述。我们还提出,对新出现的变异进行流行病学监测必须始终伴随着旨在破译可能有助于增加毒力和致病性的新优势性状的生物学研究,以便实施与人类宿主建立(相对)安全共存的最适当策略。
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