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Pros and Cons of Early and Late Skin Grafting in Children with Burns—Evaluation of Common Concepts 烧伤患儿早期和晚期植皮的利弊——一般概念的评价
Pub Date : 2022-02-22 DOI: 10.3390/ebj3010015
I. Abdelrahman, I. Steinvall, F. Sjöberg, M. Ellabban, J. Zdolsek, Moustafa Elmasry
Background: There is no consensus regarding the timing of surgery in children with smaller burn size, specifically in deep dermal burns. Delayed surgery has risks in terms of infection and delayed wound healing. Early surgery also risks the removal of potentially viable tissue. Our aim was to investigate the effect of the timing of surgical intervention on the size of the area operated on and the time to wound healing. Methods: A retrospective analysis for all children (<18 years) with burn size <20% body surface area (BSA%) during 2009–2020 who were operated on with a split-thickness skin graft. The patients were grouped by the timing of the first skin graft operation: early = operated on within 14 days of injury; delayed = operated on more than two weeks after injury. Results: A total of 84 patients were included in the study, 43 who had an early operation and 41 who had a delayed operation. There were no differences between the groups regarding burn size, or whether the burns were superficial or deep. The mean duration of healing time was seven days longer in the group with delayed operation (p = 0.001). The area operated on was somewhat larger (not significantly so) in the group who had early operation. Nine children had two skin graft operations, eight in the early group and one in the delayed group (p = 0.03). Conclusion: The patients who were operated on early had the advantage of a shorter healing time, but there was a higher rate of complementary operations and a tendency towards a larger burn excision.
背景:对于烧伤面积较小的儿童,特别是深部皮肤烧伤的手术时机尚无共识。延迟手术在感染和延迟伤口愈合方面有风险。早期手术也有切除潜在存活组织的风险。我们的目的是研究手术干预时间对手术面积和伤口愈合时间的影响。方法:回顾性分析2009-2020年所有烧伤面积<体表面积(BSA%) 20%的儿童(<18岁)行裂皮植皮手术的病例。患者按首次植皮手术时间分组:早期=伤后14天内手术;受伤后超过两周才进行手术。结果:共纳入84例患者,其中早期手术43例,延迟手术41例。两组之间在烧伤大小、烧伤是浅的还是深的方面没有差异。延迟手术组平均愈合时间延长7 d (p = 0.001)。早期手术组的手术面积稍大(差异不明显)。2次植皮9例,早期组8例,延迟组1例(p = 0.03)。结论:早期手术的患者愈合时间较短,但补充手术的比例较高,且有较大的烧伤切除的趋势。
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引用次数: 1
Infection and Burn Injury 感染和烧伤
Pub Date : 2022-02-22 DOI: 10.3390/ebj3010014
Edward J. Kelly, Mary A. Oliver, B. Carney, J. Shupp
Burn injury is debilitating and among one of the most frequently occurring traumas. Critical care improvements have allowed for increasingly positive outcomes. However, infection, whether it be localized to the site of the wound or systemic in nature, remains a serious cause of morbidity and mortality. Immune suppression predisposes the burn population to the development of invasive infections; and this along with the possibility of inhalation injury puts them at a significant risk for mortality. Emerging multi-drug-resistant pathogens, including Staphylococcus aureus, Enterococcus, Pseudomonas, Acinetobacter, Enterobacter, and yeast spp., continue to complicate clinical care measures, requiring innovative therapies and antimicrobial treatment. Close monitoring of antimicrobial regimens, strict decontamination procedures, early burn eschar removal, adequate wound closure, proper nutritional maintenance, and management of shock and resuscitation all play a significant role in mitigating infection. Novel antimicrobial therapies such as ultraviolet light, cold plasma and topical antiseptics must continue to evolve in order to lower the burden of infection in burn.
烧伤使人衰弱,是最常见的创伤之一。重症监护的改善使得结果越来越积极。然而,感染,无论是局限于伤口部位还是全身性的,仍然是发病率和死亡率的一个严重原因。免疫抑制使烧伤人群易发生侵袭性感染;这加上吸入性损伤的可能性使他们面临很大的死亡风险。新出现的多重耐药病原体,包括金黄色葡萄球菌、肠球菌、假单胞菌、不动杆菌、肠杆菌和酵母菌,继续使临床护理措施复杂化,需要创新疗法和抗菌治疗。密切监测抗菌方案、严格的去污程序、早期清除烧伤痂、适当的伤口闭合、适当的营养维持以及休克和复苏管理都在减轻感染方面发挥着重要作用。新型抗菌疗法如紫外线、冷等离子体和局部抗菌剂必须继续发展,以降低烧伤感染的负担。
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引用次数: 9
Two Modified Questionnaires for the Assessment of Nutrition Impact Symptoms in the Rehabilitation Phase after Burn Injury: A Content Validation Study 两份用于评估烧伤后康复阶段营养影响症状的修正问卷:内容验证研究
Pub Date : 2022-02-18 DOI: 10.3390/ebj3010013
Josefin Dimander, A. Andersson, A. Miclescu, F. Huss
Disease Related Appetite Questionnaire (DRAQ) and Eating Symptom Questionnaire (ESQ) are used to assess nutrition impact symptoms, which are symptoms that can negatively affect the patients’ food intake. However, these questionnaires have not yet been adapted to the needs of patients recovering from burn injuries. Our aim was therefore to develop DRAQ and ESQ for assessments of nutrition impact symptoms after burn injury. A content validation index (I-CVI) for items included in DRAQ and ESQ, regarding their relevance for possible nutrition impact symptoms in a burn-injured patient (Likert scale 1–4), was performed by an expert review group. A clarity validation by expert and non-expert reviewers was carried out. Two of the eleven questions in DRAQ and eight of the fourteen questions in ESQ were not considered relevant and were therefore removed from the questionnaires. Five additional questions were added to DRAQ and two to ESQ. A high degree of consensus on relevance (scale-content validity index average, S-CVI/Ave, 0.86 for DRAQ-burn and 0.83 for ESQ-burn) was reached in the expert group. To conclude, it is suggested that we use developed forms of DRAQ and ESQ (DRAQ-burn and ESQ-burn) for the assessment of nutrition impact symptoms, specifically during the rehabilitation phase of burn-injured patients.
采用疾病相关食欲问卷(Disease Related Appetite Questionnaire, DRAQ)和饮食症状问卷(Eating Symptom Questionnaire, ESQ)评估营养影响症状,即对患者食物摄入产生负面影响的症状。然而,这些问卷还没有适应烧伤患者康复的需要。因此,我们的目标是制定DRAQ和ESQ来评估烧伤后的营养影响症状。一个专家评审小组对DRAQ和ESQ中包含的项目进行了内容验证指数(I-CVI),以了解它们与烧伤患者可能的营养影响症状(李克特量表1-4)的相关性。由专家和非专家审稿人进行清晰度验证。DRAQ的11个问题中的2个和ESQ的14个问题中的8个被认为不相关,因此从问卷中删除。DRAQ增加了5个问题,ESQ增加了2个问题。专家组对相关性(量表-内容效度指数平均值,S-CVI/Ave, DRAQ-burn为0.86,ESQ-burn为0.83)达成了高度共识。综上所述,我们建议使用先进的DRAQ和ESQ (DRAQ-burn和ESQ-burn)来评估营养影响症状,特别是在烧伤患者的康复阶段。
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引用次数: 0
Relations among Stigma, Quality of Life, Resilience, and Life Satisfaction in Individuals with Burn Injuries 烧伤患者耻感、生活质量、恢复力和生活满意度的关系
Pub Date : 2022-02-15 DOI: 10.3390/ebj3010012
Jack D Watson, P. Perrin
This study examined the relations among burn stigma, quality of life, resilience, and life satisfaction, hypothesizing that higher stigma and lower burn-related quality of life would lead to lower life satisfaction; however, resilience would moderate this relation. A sample of 89 participants was recruited from an outpatient clinic of a burn center in a critical care hospital. Participants completed a battery of measures assessing these constructs. Results suggested that burn stigma was associated with reduced life satisfaction after accounting for other variables. Multiple regression models found that burn stigma predicted both affect and body image but not interpersonal relationship quality or sexuality. Interpersonal relationship quality, sexuality, affect, and body image all predicted life satisfaction. Both affect and body image partially accounted for the relation between stigma and life satisfaction, and resilience accounted for the relation between stigma and affect. Findings reinforce previous literature that has shown a relationship between stigma and life satisfaction but also emphasizes the role of resilience and burn-related quality of life. Individuals who experience a burn injury may have innate resilience abilities, which allow them to bounce back from stressors; thus, resilience can be a targeted strength to bootstrap in order to improve adjustment outcomes.
本研究探讨烧伤耻辱感、生活质量、恢复力和生活满意度之间的关系,假设较高的耻辱感和较低的烧伤相关生活质量会导致较低的生活满意度;然而,弹性会缓和这种关系。89名参与者的样本是从一家重症医院烧伤中心的门诊招募的。参与者完成了一系列评估这些构念的措施。结果表明,考虑到其他变量后,烧伤耻辱感与生活满意度降低有关。多元回归模型发现,烧伤污名对情感和身体形象都有预测作用,但对人际关系质量和性行为没有预测作用。人际关系质量、性、情感和身体形象都能预测生活满意度。情感和身体形象都可以部分解释耻辱感与生活满意度的关系,而心理韧性可以部分解释耻辱感与情感的关系。研究结果加强了先前的文献,表明耻辱与生活满意度之间存在关系,但也强调了恢复力和烧伤相关生活质量的作用。经历过烧伤的人可能有天生的恢复能力,这使他们能够从压力中恢复过来;因此,弹性可以作为一种有针对性的力量来引导,以改善调整结果。
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引用次数: 3
Pre-Burn Health-Related Quality of Life: Patient and Partner Perspectives 烧伤前与健康相关的生活质量:患者和伴侣的观点
Pub Date : 2022-02-11 DOI: 10.3390/ebj3010011
Elise Boersma-van Dam, H. Hofland, A. D. de Jong, N. V. Van Loey
A proxy-assessment of health-related quality of life (HRQL) may be an alternative for burn patients who are medically unable to self-report shortly after being admitted to the hospital. This study examined the patient–partner agreement on the recalled pre-injury HRQL of burn patients. In a multi-centre study of 117 patient–partner pairs, the recalled pre-burn HRQL was assessed with the EQ-5D-3L + Cognition during the acute phase following the burns. Agreement was evaluated with Kappa and ICC statistics. Burn severity and PTSD symptoms were assessed as potential predictors of disagreement. The results showed that pre-burn EQ-Index scores were similar to population norms, whereas the EQ Visual Analog Scale (EQ-VAS) scores of patients were significantly higher. Agreement varied across EQ-5D domains and, after adjusting for prevalence, was substantial to almost perfect. Average agreement on the EQ-Index and EQ-VAS was, respectively, substantial and moderate, but differences between partners were larger at lower levels of HRQL, and specifically in the pain/discomfort domain. Patient–partner differences could not be explained by the patient’s age or gender, number of surgeries, partner’s presence at the burn event, or post-traumatic stress disorder (PTSD) symptoms of either the patient or partner. In conclusion, patient–partner agreement is substantial and partner–proxy reports of pre-burn EQ-5D domains and EQ-Index scores may be used to complement or serve as a substitute for the patient’s assessment. Given the moderate agreement on the EQ-VAS, it may be less suited for proxy assessment.
健康相关生活质量代理评估(HRQL)可能是入院后医学上无法自我报告的烧伤患者的替代选择。本研究考察了烧伤患者损伤前HRQL回忆的医患共识。在一项117对患者-伴侣的多中心研究中,在烧伤后的急性期,用EQ-5D-3L +认知评估烧伤前的HRQL。用Kappa和ICC统计数据评估一致性。烧伤严重程度和创伤后应激障碍症状被评估为意见分歧的潜在预测因素。结果显示,烧伤前EQ- index评分与人群正常值相近,而患者EQ- vas评分明显高于对照组。EQ-5D各域的一致性各不相同,在调整患病率后,一致性基本达到近乎完美。EQ-Index和EQ-VAS的平均一致性分别为实质性和中等,但在HRQL水平较低时,特别是在疼痛/不适领域,伴侣之间的差异较大。患者与伴侣之间的差异不能用患者的年龄或性别、手术次数、伴侣在烧伤现场的出现或患者或伴侣的创伤后应激障碍(PTSD)症状来解释。总之,患者与伴侣的一致是实质性的,烧伤前EQ-5D结构域和EQ-Index评分的伴侣代理报告可用于补充或替代患者的评估。考虑到对EQ-VAS的适度认同,它可能不太适合代理评估。
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引用次数: 0
When Is Being Sad on the Burn Unit Pathological? Differential Diagnosis of Demoralization, Adjustment Disorder and Major Depressive Disorder in Burn Survivors 什么时候在烧伤科伤心是病态的?烧伤幸存者士气低落、适应障碍和重度抑郁障碍的鉴别诊断
Pub Date : 2022-02-10 DOI: 10.3390/ebj3010010
M. Beal, S. Lerman, Idris E. Leppla
Many burn survivors have pre-existing psychiatric conditions or develop psychological or psychiatric symptoms over the course of their hospital stay. Patients often present with low mood and neurovegetative symptoms which can be conceptualized as demoralization, adjustment disorder, or major depressive disorder. We review the literature on these syndromes in burn survivors and present three cases that highlight the continuum of these syndromes for patients who present with symptoms of depression following a burn injury. We discuss the clinical challenges of differentiating these syndromes as well as psychotherapeutic and psychopharmacologic considerations and recommendations.
许多烧伤幸存者都有先前存在的精神疾病,或者在住院期间出现心理或精神症状。患者通常表现为情绪低落和神经植物症状,这些症状可被定义为士气低落、适应障碍或重度抑郁症。我们回顾了烧伤幸存者中这些综合征的文献,并提出了三个病例,突出了烧伤后出现抑郁症状的患者的这些综合征的连续性。我们讨论了鉴别这些综合征的临床挑战,以及心理治疗和精神药理学的考虑和建议。
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引用次数: 0
Resilience and Posttraumatic Growth after Burn: A Review of Barriers, Enablers, and Interventions to Improve Psychological Recovery 烧伤后的恢复力和创伤后生长:改善心理恢复的障碍、促进因素和干预措施综述
Pub Date : 2022-02-09 DOI: 10.3390/ebj3010009
A. Woolard, Indijah Bullman, A. Allahham, Treya M Long, H. Milroy, Fiona Wood, Lisa Martin
Burn injuries are traumatic experiences that can detrimentally impact an individual’s psychological and emotional wellbeing. Despite this, some survivors adapt to psychosocial challenges better than others despite similar characteristics relating to the burn. Positive adaptation is known as resilience or posttraumatic growth, depending on the trajectory and process. This review aimed to describe the constructs of resiliency and growth within the burn injury context, examine the risk factors that inhibit resilience or growth after burn (barriers), the factors that promote resilience or growth after burn (enablers), and finally to assess the impact of interventions that have been tested that may facilitate resilience or growth after burn. This review was performed according to the recently updated Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines. An electronic search was conducted in November 2021 on the databases PubMed, Medline (1966-present), Embase (1974-present), PsycINFO for English-language peer-reviewed academic articles. There were 33 studies included in the review. Findings were mixed for most studies; however, there were factors related to demographic information (age, gender), burn-specific characteristics (TBSA, time since burn), person-specific factors (personality, coping style), psychopathology (depression, PTSD), and psychosocial factors (social support, spirituality/religion, life purpose) that were evidenced to be related to resilience and growth. One qualitative study evaluated an intervention, and this study showed that a social camp for burn patients can promote resilience. This study has presented a variety of factors that inhibit or encourage resilience and growth, such as demographic, individual, and social factors. We also present suggestions on interventions that may be used to promote growth following this adverse event, such as improving social support, coping styles and deliberate positive introspection.
烧伤是一种创伤性经历,会对个人的心理和情感健康产生不利影响。尽管如此,尽管与烧伤有关的特征相似,但一些幸存者比其他人更好地适应社会心理挑战。积极适应被称为复原力或创伤后成长,取决于轨迹和过程。本综述旨在描述烧伤背景下恢复力和生长的结构,检查抑制恢复力或烧伤后生长的风险因素(障碍),促进恢复力或烧伤后生长的因素(使能因素),最后评估已测试的可能促进恢复力或烧伤后生长的干预措施的影响。本综述根据最近更新的系统评价和荟萃分析(PRISMA)指南的首选报告项目进行。我们于2021年11月对PubMed、Medline(1966年至今)、Embase(1974年至今)、PsycINFO等数据库进行了一次电子检索,以检索同行评议的英文学术文章。该综述纳入了33项研究。大多数研究的结果好坏参半;然而,人口统计学信息(年龄、性别)、烧伤特异性特征(TBSA、烧伤时间)、个人特异性因素(个性、应对方式)、精神病理(抑郁、创伤后应激障碍)和社会心理因素(社会支持、精神/宗教、生活目的)被证明与恢复力和成长有关。一项定性研究评估了一项干预措施,该研究表明,烧伤患者的社会营地可以促进恢复力。本研究提出了多种抑制或促进弹性和成长的因素,如人口、个人和社会因素。我们还提出了一些干预建议,可以用来促进这种不良事件后的成长,如改善社会支持,应对方式和有意识的积极反省。
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引用次数: 3
Screening and Assessment for Psychological Distress among Burn Survivors 烧伤幸存者心理困扰的筛选与评估
Pub Date : 2022-02-03 DOI: 10.3390/ebj3010008
Valerie G. Loehr, W. Goette, Kimberly Roaten
Given the high rates of psychological distress after burn injury, thorough screening and assessment for psychosocial factors and psychiatric pathology should be routinely completed for individuals with burn injuries. Burn survivors experience unique psychosocial changes and injury sequelae, such as body image concerns, trauma-related pathology, and itching. Screening for these factors is integral to understanding how these may be contributing to psychological distress. Proactively identifying distress and psychiatric pathology is important to optimize physical and emotional outcomes.aim of this manuscript is to summarize information about the available screening and assessment tools for psychological distress among burn survivors.
鉴于烧伤后心理困扰的高发率,应该对烧伤患者进行全面的心理社会因素和精神病理学筛查和评估。烧伤幸存者会经历独特的心理社会变化和损伤后遗症,如身体形象问题、创伤相关病理和瘙痒。筛查这些因素对于理解这些因素如何导致心理困扰是不可或缺的。主动识别痛苦和精神病理对于优化身体和情绪结果很重要。这篇论文的目的是总结关于在烧伤幸存者中可用的筛选和评估工具的信息。
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引用次数: 4
Acknowledgment to Reviewers of European Burn Journal in 2021 向欧洲烧伤杂志2021年审稿人致谢
Pub Date : 2022-01-28 DOI: 10.3390/ebj3010007
Rigorous peer-reviews are the basis of high-quality academic publishing [...]
严格的同行评议是高质量学术出版的基础[…]
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引用次数: 0
The Use of Intact Fish Skin as a Novel Treatment Method for Deep Dermal Burns Following Enzymatic Debridement: A Retrospective Case-Control Study 使用完整鱼皮作为酶清创后深层皮肤烧伤的新治疗方法:回顾性病例对照研究
Pub Date : 2022-01-27 DOI: 10.3390/ebj3010006
C. Wallner, Jana Holtermann, M. Drysch, S. Schmidt, F. Reinkemeier, J. Wagner, M. Dadras, A. Sogorski, K. Houschyar, M. Becerikli, M. Lehnhardt, B. Behr
Background: The optimal therapy for deep burn wounds is based on the early debridement of necrotic tissue followed by wound coverage to avoid a systemic inflammatory response and optimize scar-free healing. The outcomes are affected by available resources and underlying patient factors, which represent challenges in burn care and suboptimal outcomes. In this study, we aimed to determine optimal burn-wound management using enzymatic debridement (NexoBrid™, MediWound Germany GmbH, Rüsselsheim, Germany) and intact fish skin (Kerecis® Omega3 Wound, Isafjordur, Iceland). Methods: In this retrospective case series, 12 patients with superficial or deep dermal burn wounds were treated with enzymatic debridement followed by fish skin, Suprathel® (PolyMedics Innovations GmbH, Denkendorf, Germany), or a split-thickness skin graft (STSG). Patients’ outcomes regarding healing and scar quality were collected objectively and subjectively for 12 months after the burn injury. Results: Wounds treated with fish skin demonstrated accelerated wound healing, a significantly higher water-storage capacity, and better pain relief. Furthermore, improved functional and cosmetic outcomes, such as elasticity, skin thickness, and pigmentation, were demonstrated. The pain and itch expressed as POSAS scores (Patient and Observer Scar Assessment Scale) for fish skin decreased compared to those for wounds managed with an STSG or Suprathel. Importantly, fish skin-treated wounds had significantly improved sebum production and skin elasticity than those treated with Suprathel but showed no significant superiority compared to STSG-treated wounds. Conclusions: Enzymatic debridement in combination with intact fish skin grafts resulted in the faster healing of burn wounds and better functional and aesthetic outcomes than split-thickness skin grafts and Suprathel treatment.
背景:深度烧伤创面的最佳治疗方法是早期清除坏死组织,然后覆盖创面,以避免全身炎症反应并优化无疤痕愈合。结果受可用资源和潜在患者因素的影响,这代表了烧伤护理和次优结果的挑战。在这项研究中,我们旨在确定使用酶清创(NexoBrid™,MediWound Germany GmbH, r sselsheim,德国)和完整鱼皮(Kerecis®Omega3 Wound, Isafjordur,冰岛)的最佳烧伤创面管理。方法:在这个回顾性的病例系列中,12例浅表或深部皮肤烧伤创面患者采用酶清创治疗,随后采用鱼皮、Suprathel®(PolyMedics Innovations GmbH, Denkendorf, Germany)或裂厚皮肤移植(STSG)。客观和主观地收集烧伤后12个月患者愈合和疤痕质量的结果。结果:鱼皮处理的伤口愈合速度加快,储水能力显著提高,疼痛缓解效果更好。此外,改善功能和美容结果,如弹性,皮肤厚度和色素沉着,被证明。与使用STSG或Suprathel治疗的伤口相比,鱼皮的疼痛和瘙痒以POSAS评分(患者和观察者疤痕评估量表)表示。重要的是,鱼皮处理的伤口比Suprathel处理的伤口有显著改善皮脂生成和皮肤弹性,但与stsg处理的伤口相比没有显著的优势。结论:酶清创联合完整鱼皮移植治疗烧伤创面愈合更快,功能和美观效果优于裂皮移植和Suprathel治疗。
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引用次数: 8
期刊
European burn journal
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