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Complications of percutaneously placed uncovered metallic biliary stents for malignant obstruction: a systematic review. 经皮放置金属胆道支架治疗恶性梗阻的并发症:系统回顾。
IF 2.3 Pub Date : 2025-08-05 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1639323
Jonathan Bock, Christopher J Reisenauer, Michael C Jundt, Matthew R Augustine, Richard G Frimpong, Edwin A Takahashi

Background: The aim of this systematic review was to determine the patency and complications related to percutaneous metallic biliary stent placement for malignant biliary obstruction in the current literature.

Methods: This review was performed using the Preferred Reporting Items of Systematic Reviews and Meta-Analyses guidelines. EMBASE and PubMed were queried yielding 891 articles, 18 of which were included in the final analysis. The Newcastle-Ottawa Quality Assessment Scale was used to appraise article quality. Patient demographics, technical success rate, and procedure outcomes were recorded. Complications were classified as "major" if they resulted in blood transfusion or additional invasive procedures or were reported as such in the literature. Complications that did not meet these criteria were classified as "minor".

Results: A total of 1,453 patients (677 female; weighted age 66.8 years) underwent biliary stent placement. The weighted technical success rate was 97.7%. The incidence of stent occlusion was 13.5% with 6.6% of patients requiring further intervention to maintain patency. There were 277 (19.1%) complications, of which 87 were classified as major. The most common complications were pancreatitis (93, 6.4%), cholangitis (69, 4.8%), and bleeding (64, 4.4%). In cases of bleeding, 4.7% of patients needed a blood transfusion and 15.6% required a procedure to treat bleeding. There were 6 (0.4%) procedure-related deaths.

Conclusion: In conclusion, percutaneous metallic stent placement for malignant biliary obstruction has a high technical success rate and relatively low rate of occlusion. Although nearly one in five procedures resulted in a complication, most cases were minor.

背景:本系统综述的目的是确定目前文献中经皮胆道金属支架置入术治疗恶性胆道梗阻的通畅性和并发症。方法:本综述采用系统评价和荟萃分析指南的首选报告项目进行。查询EMBASE和PubMed共得到891篇文章,其中18篇被纳入最终分析。采用纽卡斯尔-渥太华质量评定量表评价文章质量。记录患者人口统计、技术成功率和手术结果。如果并发症导致输血或额外的侵入性手术,或在文献中报道,则将其归类为“严重”并发症。不符合这些标准的并发症被归类为“轻微”。结果:共1453例患者(女性677例,加权年龄66.8岁)行胆道支架置入术。加权技术成功率为97.7%。支架闭塞的发生率为13.5%,其中6.6%的患者需要进一步干预以维持通畅。并发症277例(19.1%),其中严重并发症87例。最常见的并发症是胰腺炎(93例,6.4%)、胆管炎(69例,4.8%)和出血(64例,4.4%)。在出血病例中,4.7%的患者需要输血,15.6%的患者需要进行出血治疗。手术相关死亡6例(0.4%)。结论:经皮金属支架置入术治疗恶性胆道梗阻技术成功率高,闭塞率相对较低。虽然近五分之一的手术导致并发症,但大多数病例都是轻微的。
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引用次数: 0
WaveAttention-ResNet: a deep learning-based intelligent diagnostic model for the auxiliary diagnosis of multiple retinal diseases. WaveAttention-ResNet:基于深度学习的多种视网膜疾病辅助诊断智能诊断模型。
IF 2.3 Pub Date : 2025-07-29 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1608052
Biao Guo, Daqing Wang, Ruiqi Zhang, Jia Hou, Wenchao Liu, YongFei Wu, Xudong Yang, Lijuan Zhang

Objective: This study constructs a deep learning-based combined algorithm named WaveAttention ResNet (WARN) to investigate the classification accuracy for seven common retinal diseases and the feasibility of AI-assisted diagnosis in this field.

Methods: First, a deep learning-based classification network is constructed. The network is built upon ResNet18, integrated with the Convolutional Block Attention Module (CBAM) and wavelet convolution modules, forming the WARN method for retinal disease classification. Second, the public OCTDL dataset is used to train WARN, which contains classification data for seven retinal disease types: age-related macular degeneration (AMD), diabetic macular edema (DME), epiretinal membrane (ERM), normal (NO), retinal artery occlusion (RAO), retinal vein occlusion (RVO), and vitreomacular interface disease (VID). During this process, ablation experiments and significance tests are conducted on WARN, and comprehensive analyses of various indicators for WARN, ResNet-18, ResNet-50, Swin Transformer v2, EfficientNet, and Vision Transformer (ViT) are performed in retinal disease classification tasks. Finally, data provided by Shanxi Eye Hospital are used for testing, and classification results are analyzed.

Results: WARN demonstrates excellent performance on the public OCTDL dataset. Ablation experiments and significance tests confirm the effectiveness of WARN, achieving an accuracy of 90.68%, F1-score of 91.29%, AUC of 97.50%, precision of 93.31%, and recall of 90.68% with relatively short training time. In the dataset from Shanxi Eye Hospital, WARN also performs well, with a recall of 90.85%, precision of 79.94%, and accuracy of 89.18%.

Conclusion: This study fully confirms that the constructed WARN is efficient and feasible for classifying seven common retinal diseases. It further highlights the enormous potential and broad application prospects of AI technology in the field of auxiliary medical diagnosis.

目的:构建基于深度学习的WaveAttention ResNet (WARN)组合算法,探讨7种常见视网膜疾病的分类准确率及人工智能辅助诊断在该领域的可行性。方法:首先,构建基于深度学习的分类网络。该网络以ResNet18为基础,结合卷积块注意模块(Convolutional Block Attention Module, CBAM)和小波卷积模块,形成视网膜疾病分类的WARN方法。其次,使用公开的OCTDL数据集训练WARN,该数据集包含7种视网膜疾病类型的分类数据:年龄相关性黄斑变性(AMD)、糖尿病性黄斑水肿(DME)、视网膜前膜(ERM)、正常(NO)、视网膜动脉闭塞(RAO)、视网膜静脉闭塞(RVO)和玻璃体黄斑界面病(VID)。在此过程中,对WARN进行消融实验和显著性检验,综合分析WARN、ResNet-18、ResNet-50、Swin Transformer v2、EfficientNet、Vision Transformer (ViT)在视网膜疾病分类任务中的各项指标。最后利用山西省眼科医院提供的数据进行检验,并对分类结果进行分析。结果:WARN在公共OCTDL数据集上展示了出色的性能。消融实验和显著性检验证实了WARN的有效性,训练时间相对较短,准确率为90.68%,f1得分为91.29%,AUC为97.50%,准确率为93.31%,召回率为90.68%。在山西眼科医院的数据集中,WARN也表现良好,召回率为90.85%,准确率为79.94%,准确率为89.18%。结论:本研究充分证实了构建的WARN对7种常见视网膜疾病的分类是有效可行的。进一步凸显了人工智能技术在医疗辅助诊断领域的巨大潜力和广阔应用前景。
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引用次数: 0
Editorial: Artificial intelligence in radiology and radiation oncology. 社论:放射学和放射肿瘤学中的人工智能。
IF 2.3 Pub Date : 2025-07-23 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1657119
Curtise K C Ng, Vincent W S Leung
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引用次数: 0
Severe complications following transarterial microembolization for a micro arterio-venous fistula in a patient with chronic venous ulcer: a case report. 慢性静脉溃疡患者经动脉微栓塞治疗微动静脉瘘后的严重并发症1例报告。
IF 2.3 Pub Date : 2025-07-18 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1613940
Wankarn Boonlorm, Panat Nisityotakul

Transarterial microembolization (TAME) has gained recognition as a minimally invasive treatment for chronic musculoskeletal pain, demonstrating significant efficacy with a favorable safety profile ( 1, 2). However, complications remain underreported. This case report describes the first documented severe adverse event in a patient with a chronic venous ulcer undergoing TAME for a micro arteriovenous fistula (AVF). The patient developed significant complications, including extensive leg swelling, skin changes, and cellulitis requiring prolonged inpatient care. These findings highlight the importance of patient selection and embolic agent considerations to mitigate potential risks associated with TAME.

经动脉微栓塞(TAME)已被公认为慢性肌肉骨骼疼痛的微创治疗方法,具有显著的疗效和良好的安全性(1,2)。然而,并发症的报道仍然不足。本病例报告描述了第一个记录严重不良事件的患者慢性静脉溃疡接受TAME微动静脉瘘(AVF)。患者出现了明显的并发症,包括广泛的腿部肿胀、皮肤变化和蜂窝织炎,需要长期住院治疗。这些发现强调了患者选择和栓塞剂考虑的重要性,以减轻与TAME相关的潜在风险。
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引用次数: 0
The oral fingerprint: rapid 3D comparison of palatal rugae for forensic identification. 口腔指纹:用于法医鉴定的腭纹快速三维比较。
IF 2.3 Pub Date : 2025-07-18 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1638294
Anika Kofod Petersen, Palle Villesen, Line Staun Larsen

Intoduction: The palatal rugae have been suggested to be just as unique as the human fingerprint. Therefore, endeavors have been made to utilize this uniqueness for the identification of disaster victims. With the rise of digital 3D dental data, computational comparisons of palatal rugae have become possible. But a direct comparison of the full palatal scan by iterative closest point (ICP) has shown to be tedious and demands a knowledge of superimposition software.

Methods: Here, we propose (1) an automatic extraction of the palatal rugae ridges from the 3D scans, followed by (2) ICP of the extracted ridges.

Results: Pairwise comparisons of palates take less than a second, and in this study, it was possible to distinguish between palates from the same individual vs. palates from different individuals with a receiver operating characteristic area-under-the-curve of 0.994.

Discussion: This shows that the extraction of the palatal rugae ridges is a potential efficient addition to the toolbox of a forensic odontologist for disaster victim identification.

有人认为,腭纹就像人类的指纹一样独特。因此,人们努力利用这种独特性来识别灾民。随着数字三维牙科数据的兴起,计算腭纹的比较已经成为可能。但是用迭代最近点(ICP)对全腭扫描进行直接比较已经证明是乏味的,并且需要具备叠加软件的知识。方法:在此,我们提出(1)从三维扫描中自动提取腭纹脊,然后(2)对提取的纹脊进行ICP。结果:味觉的两两比较只需要不到一秒的时间,在本研究中,接收者操作特征曲线下面积为0.994,可以区分来自同一个体的味觉和来自不同个体的味觉。讨论:这表明,提取腭纹脊是一个潜在的有效的工具箱,法医齿科医生的灾难受害者鉴定。
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引用次数: 0
Assessing the consistency of CT-based ventilation imaging under noise reduction processing with simulated quantum noise using a nonrigid alveoli phantom. 利用非刚性肺泡模体模拟量子噪声评估降噪处理下ct通气成像的一致性。
Pub Date : 2025-07-09 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1567267
Shin Miyakawa, Hiraku Fuse, Kenji Yasue, Norikazu Koori, Masato Takahashi, Hiroki Nosaka, Shunsuke Moriya, Fumihiro Tomita, Tatsuya Fujisaki

Background: Previous studies have reported that quantum noise inherently present in CT images hinders the generation of CT-based ventilation image (CTVI), while quantum noise reduction approaches that do not affect CTVI have not yet been reported.

Aims: The purpose of this study was to evaluate the impact of noise reduction preprocessing on the accuracy and robustness of CTVI in relation to quantum noise present in CT images.

Methods and material: To reproduce the quantum noise, Gaussian noise (SD: 30, 80, 150 HU) was added to each inhalation and exhalation CT image. CTVIref and CTVInoise was generated from CTref and CTnoise. A median filter and the noise reduction by the CNN were also applied to the CT image, which contained the quantum noise, and CTVImed and CTVIcnn was created in the same manner as CTVIref. We evaluated whether the regions classified as high, middle, or low in CTVIref were accurately represented as high, middle, or low in CTVInoise, CTVImed and CTVIcnn. Additionally, to evaluate the ventilation function of each voxel, we compared two-dimensional histograms of CTVIref, CTVInoise, CTVImed and CTVIcnn.

Statistical analysis used: Cohen's kappa coefficient and Spearman's correlation were used to assess the agreement between CTVIref and each of the following: CTVInoise, CTVImed, and CTVIcnn.

Results: CTVIcnn significantly improved categorical consistency and voxel-level correlation of CTVI, particularly under high-noise conditions (150 HU), outperforming both CTVInoise and CTVImed.

Conclusions: CNN-based denoising effectively improved the accuracy and robustness of CTVI under quantum noise.

背景:以往的研究报道了CT图像中固有的量子噪声会阻碍基于CT的通风图像(CTVI)的生成,而不影响CTVI的量子降噪方法尚未报道。目的:本研究的目的是评估降噪预处理对CT图像中存在的量子噪声对CTVI精度和鲁棒性的影响。方法和材料:为了再现量子噪声,在每个吸气和呼气CT图像中加入高斯噪声(SD: 30、80、150 HU)。CTVIref和CTVInoise分别由cttref和CTnoise生成。对含有量子噪声的CT图像进行中值滤波和CNN去噪,并按照与CTVIref相同的方法创建ctvied和ctvinn。我们评估了在CTVIref中被分类为高、中、低的区域在CTVInoise、ctvied和ctvinn中是否被准确地表示为高、中、低。此外,为了评估每个体素的通气功能,我们比较了CTVIref、CTVInoise、ctviimed和CTVIcnn的二维直方图。使用的统计分析:使用Cohen’s kappa系数和Spearman’s相关性来评估CTVIref与以下各项的一致性:ctvioise、ctviimed和ctvinn。结果:CTVIcnn显著提高了CTVI的分类一致性和体素级相关性,特别是在高噪声条件下(150 HU),优于CTVInoise和CTVImed。结论:基于cnn的去噪有效提高了量子噪声下CTVI的准确性和鲁棒性。
{"title":"Assessing the consistency of CT-based ventilation imaging under noise reduction processing with simulated quantum noise using a nonrigid alveoli phantom.","authors":"Shin Miyakawa, Hiraku Fuse, Kenji Yasue, Norikazu Koori, Masato Takahashi, Hiroki Nosaka, Shunsuke Moriya, Fumihiro Tomita, Tatsuya Fujisaki","doi":"10.3389/fradi.2025.1567267","DOIUrl":"10.3389/fradi.2025.1567267","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have reported that quantum noise inherently present in CT images hinders the generation of CT-based ventilation image (CTVI), while quantum noise reduction approaches that do not affect CTVI have not yet been reported.</p><p><strong>Aims: </strong>The purpose of this study was to evaluate the impact of noise reduction preprocessing on the accuracy and robustness of CTVI in relation to quantum noise present in CT images.</p><p><strong>Methods and material: </strong>To reproduce the quantum noise, Gaussian noise (SD: 30, 80, 150 HU) was added to each inhalation and exhalation CT image. CTVI<sub>ref</sub> and CTVI<sub>noise</sub> was generated from CT<sub>ref</sub> and CT<sub>noise</sub>. A median filter and the noise reduction by the CNN were also applied to the CT image, which contained the quantum noise, and CTVI<sub>med</sub> and CTVI<sub>cnn</sub> was created in the same manner as CTVI<sub>ref</sub>. We evaluated whether the regions classified as high, middle, or low in CTVI<sub>ref</sub> were accurately represented as high, middle, or low in CTVI<sub>noise</sub>, CTVI<sub>med</sub> and CTVI<sub>cnn</sub>. Additionally, to evaluate the ventilation function of each voxel, we compared two-dimensional histograms of CTVI<sub>ref</sub>, CTVI<sub>noise</sub>, CTVI<sub>med</sub> and CTVI<sub>cnn</sub>.</p><p><strong>Statistical analysis used: </strong>Cohen's kappa coefficient and Spearman's correlation were used to assess the agreement between CTVI<sub>ref</sub> and each of the following: CTVI<sub>noise</sub>, CTVI<sub>med</sub>, and CTVI<sub>cnn</sub>.</p><p><strong>Results: </strong>CTVI<sub>cnn</sub> significantly improved categorical consistency and voxel-level correlation of CTVI, particularly under high-noise conditions (150 HU), outperforming both CTVI<sub>noise</sub> and CTVI<sub>med</sub>.</p><p><strong>Conclusions: </strong>CNN-based denoising effectively improved the accuracy and robustness of CTVI under quantum noise.</p>","PeriodicalId":73101,"journal":{"name":"Frontiers in radiology","volume":"5 ","pages":"1567267"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12283728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain tumor segmentation using deep learning: high performance with minimized MRI data. 使用深度学习的脑肿瘤分割:最小化MRI数据的高性能。
Pub Date : 2025-07-08 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1616293
Jacky Huang, Banu Yagmurlu, Powell Molleti, Richard Lee, Abigail VanderPloeg, Humaira Noor, Rohan Bareja, Yiheng Li, Michael Iv, Haruka Itakura

Purpose: Brain tumor segmentation with MRI is a challenging task, traditionally relying on manual delineation of regions-of-interest across multiple imaging sequences. However, this data-intensive approach is time-consuming. We aimed to optimize the process by using a deep learning (DL) based model while minimizing the number of MRI sequences required to segment gliomas.

Methods: We trained a 3D U-Net DL model using the annotated 2018 MICCAI BraTS dataset (training dataset, n = 285), focusing on sub-segmenting enhancing tumor (ET) and tumor core (TC). We compared the performances of models trained on four different combinations of MRI sequences: T1C-only, FLAIR-only, T1C + FLAIR and T1 + T2 + T1C + FLAIR to evaluate whether a smaller MRI data subset could achieve comparable performance. We evaluated the performance on the four different sequence combinations using 5-fold cross-validation on the training dataset, then on our test dataset (n = 358) consisting of samples from a separately held-out 2018 BraTS validation set (n = 66) and 2021 BraTS datasets (n = 292). Dice scores on both cross-validation and test datasets were assessed to measure model performance.

Results: Dice scores on cross-validation showed that T1C + FLAIR (ET: 0.814, TC: 0.856) matched or outperformed those of T1 + T2 + T1C + FLAIR (ET: 0.785, TC: 0.841), T1C-only (ET: 0.781, TC: 0.852) and FLAIR-only (ET: 0.008, TC: 0.619). Results on the test dataset also showed that T1C + FLAIR (ET: 0.867, TC: 0.926) matched or outperformed those of T1 + T2 + T1C + FLAIR (ET: 0.835, TC: 0.908), T1C-only (ET: 0.726, TC: 0.928), and FLAIR-only (ET: 0.056, TC: 0.543). T1C + FLAIR excelled in both ET and TC, exceeding the performance of the four-sequence dataset. T1C-only matched T1C + FLAIR in TC performance. Similarly, T1C and T1C + FLAIR also outperformed in ET delineation by sensitivity (0.829) and Hausdorff distance (5.964) on the test set. Across all configurations, specificity remained high (≥0.958). T1C performed well in TC delineation (sensitivity: 0.737), but the inclusion of all sequences led to improvement (0.754). Hausdorff distances clustered in a narrow range (17.622-33.812) for TC delineation across the configurations.

Conclusions: DL-based brain tumor segmentation can achieve high accuracy using only two MRI sequences (T1C + FLAIR). Reduction of multiple sequence dependency may enhance DL generalizability and dissemination in both clinical and research contexts. Our findings may ultimately help mitigate human labor intensity of a complex task integral to medical imaging analysis.

目的:脑肿瘤MRI分割是一项具有挑战性的任务,传统上依赖于手动划定多个成像序列的兴趣区域。然而,这种数据密集型方法非常耗时。我们的目标是通过使用基于深度学习(DL)的模型来优化这一过程,同时最大限度地减少分割胶质瘤所需的MRI序列数量。方法:使用带注释的2018 MICCAI BraTS数据集(n = 285)训练三维U-Net DL模型,重点关注亚分割增强肿瘤(ET)和肿瘤核心(TC)。我们比较了在四种不同MRI序列组合上训练的模型的性能:T1C-only、FLAIR-only、T1C + FLAIR和T1 + T2 + T1C + FLAIR,以评估更小的MRI数据子集是否可以达到类似的性能。我们在训练数据集上使用5倍交叉验证评估了四种不同序列组合的性能,然后在我们的测试数据集(n = 358)上评估了性能,该数据集由来自2018年BraTS验证集(n = 66)和2021年BraTS数据集(n = 292)的样本组成。对交叉验证和测试数据集的骰子得分进行评估,以衡量模型的性能。结果:交叉验证的Dice评分显示,T1C + FLAIR (ET: 0.814, TC: 0.856)与T1 + T2 + T1C + FLAIR (ET: 0.785, TC: 0.841)、T1C-only (ET: 0.781, TC: 0.852)和FLAIR-only (ET: 0.008, TC: 0.619)相当或优于T1 + T2 + T1C + FLAIR (ET: 0.781, TC: 0.852)。测试数据集的结果还显示,T1C + FLAIR (ET: 0.867, TC: 0.926)与T1 + T2 + T1C + FLAIR (ET: 0.835, TC: 0.908)、T1C-only (ET: 0.726, TC: 0.928)和FLAIR-only (ET: 0.056, TC: 0.543)相当或优于T1 + T2 + T1C + FLAIR (ET: 0.835, TC: 0.908)。T1C + FLAIR在ET和TC方面均表现优异,超过了四序列数据集的表现。T1C在TC表现上仅与T1C + FLAIR相匹配。同样,T1C和T1C + FLAIR在ET描绘方面也优于测试集的灵敏度(0.829)和豪斯多夫距离(5.964)。在所有配置中,特异性仍然很高(≥0.958)。T1C在TC描述中表现良好(敏感性:0.737),但纳入所有序列导致改善(0.754)。Hausdorff距离聚集在一个较窄的范围内(17.622-33.812)。结论:基于dl的脑肿瘤分割仅使用两个MRI序列(T1C + FLAIR)即可达到较高的准确性。减少多序列依赖性可以增强DL在临床和研究中的推广和传播。我们的研究结果可能最终有助于减轻医学成像分析中复杂任务的人类劳动强度。
{"title":"Brain tumor segmentation using deep learning: high performance with minimized MRI data.","authors":"Jacky Huang, Banu Yagmurlu, Powell Molleti, Richard Lee, Abigail VanderPloeg, Humaira Noor, Rohan Bareja, Yiheng Li, Michael Iv, Haruka Itakura","doi":"10.3389/fradi.2025.1616293","DOIUrl":"10.3389/fradi.2025.1616293","url":null,"abstract":"<p><strong>Purpose: </strong>Brain tumor segmentation with MRI is a challenging task, traditionally relying on manual delineation of regions-of-interest across multiple imaging sequences. However, this data-intensive approach is time-consuming. We aimed to optimize the process by using a deep learning (DL) based model while minimizing the number of MRI sequences required to segment gliomas.</p><p><strong>Methods: </strong>We trained a 3D U-Net DL model using the annotated 2018 MICCAI BraTS dataset (training dataset, <i>n</i> = 285), focusing on sub-segmenting enhancing tumor (ET) and tumor core (TC). We compared the performances of models trained on four different combinations of MRI sequences: T1C-only, FLAIR-only, T1C + FLAIR and T1 + T2 + T1C + FLAIR to evaluate whether a smaller MRI data subset could achieve comparable performance. We evaluated the performance on the four different sequence combinations using 5-fold cross-validation on the training dataset, then on our test dataset (<i>n</i> = 358) consisting of samples from a separately held-out 2018 BraTS validation set (<i>n</i> = 66) and 2021 BraTS datasets (<i>n</i> = 292). Dice scores on both cross-validation and test datasets were assessed to measure model performance.</p><p><strong>Results: </strong>Dice scores on cross-validation showed that T1C + FLAIR (ET: 0.814, TC: 0.856) matched or outperformed those of T1 + T2 + T1C + FLAIR (ET: 0.785, TC: 0.841), T1C-only (ET: 0.781, TC: 0.852) and FLAIR-only (ET: 0.008, TC: 0.619). Results on the test dataset also showed that T1C + FLAIR (ET: 0.867, TC: 0.926) matched or outperformed those of T1 + T2 + T1C + FLAIR (ET: 0.835, TC: 0.908), T1C-only (ET: 0.726, TC: 0.928), and FLAIR-only (ET: 0.056, TC: 0.543). T1C + FLAIR excelled in both ET and TC, exceeding the performance of the four-sequence dataset. T1C-only matched T1C + FLAIR in TC performance. Similarly<b>,</b> T1C and T1C + FLAIR also outperformed in ET delineation by sensitivity (0.829) and Hausdorff distance (5.964) on the test set. Across all configurations, specificity remained high (≥0.958). T1C performed well in TC delineation (sensitivity: 0.737), but the inclusion of all sequences led to improvement (0.754). Hausdorff distances clustered in a narrow range (17.622-33.812) for TC delineation across the configurations.</p><p><strong>Conclusions: </strong>DL-based brain tumor segmentation can achieve high accuracy using only two MRI sequences (T1C + FLAIR). Reduction of multiple sequence dependency may enhance DL generalizability and dissemination in both clinical and research contexts. Our findings may ultimately help mitigate human labor intensity of a complex task integral to medical imaging analysis.</p>","PeriodicalId":73101,"journal":{"name":"Frontiers in radiology","volume":"5 ","pages":"1616293"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2D-cranial T1-black-blood MRI in suspected giant cell arteritis-measurement of vessel wall thickness does not give a diagnostic advantage compared to visual scoring alone. 疑似巨细胞性动脉的2d -颅t1 -黑血MRI -测量血管壁厚度与单独的视觉评分相比并不能提供诊断优势。
Pub Date : 2025-07-01 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1597938
Pascal Seitz, Susana Bucher, Lukas Bütikofer, Britta Maurer, Harald Marcel Bonel, Fabian Lötscher, Luca Seitz

Objectives: To compare two established scoring schemes for the 2D-T1-weighted "black-blood" MRI sequence (T1-BB) for superficial cranial arteries (SCA) in the diagnosis of giant cell arteritis (GCA).

Methods: Ten arterial segments were evaluated in T1-BB images with two different methods: a visual semiquantitative scheme (T1-BB-VISUAL) and a composite scheme that included both the semiquantitative assessment and a quantitative wall thickness measurement (T1-BB-COMP). The expert clinical diagnosis after ≥6 months of follow-up was the diagnostic reference standard. Diagnostic accuracy and agreement on the segment and patient levels were evaluated for the two different rating schemes.

Results: Retrospectively, 151 consecutive patients with clinically suspected GCA were included. The study cohort consisted of 82 patients with and 69 without GCA. For the T1-BB-COMP and the T1-BB-VISUAL, the sensitivity was 81.7% vs. 87.8% (p = 0.025), the specificity was 91.3% vs. 88.4% (p = 0.16) and the proportion of correct diagnoses was 86.1% vs. 88.1% (p = 0.26), respectively. The overall agreement between the two methods for 1,201 rated arterial segments was very good at 91.6% with a kappa of 0.80. The agreement was higher for segments with a larger calibre than for smaller segments: common superficial temporal arteries 98.0%, occipital arteries 93.2%, frontal branches 89.8% and parietal branches 86.9%. The correlation of wall thickness measurements between readers was strong (Spearman's rho of 0.68). The time needed to apply the T1-BB-VISUAL was about half as long as for the T1-BB-COMP (4.5 vs. 8.95 minutes).

Conclusion: In suspected GCA, the additional measurement of the wall thickness of SCAs in 2D-T1-BB MRI does not lead to a better diagnostic performance compared to visual semiquantitative scoring alone. Visual scoring is preferred due to higher efficiency and reliability.

目的:比较两种已建立的脑浅动脉(SCA) 2d - t1加权“黑血”MRI序列(T1-BB)在巨细胞动脉炎(GCA)诊断中的评分方案。方法:采用视觉半定量方案(T1-BB- visual)和半定量评估和定量壁厚测量的复合方案(T1-BB- comp)两种不同的方法对T1-BB图像中的10条动脉段进行评估。随访≥6个月专家临床诊断为诊断参考标准。对两种不同的评分方案进行了诊断准确性和对节段和患者水平的一致性评估。结果:回顾性分析了151例临床怀疑为GCA的患者。研究队列包括82例GCA患者和69例非GCA患者。T1-BB-COMP和T1-BB-VISUAL的敏感性分别为81.7%和87.8% (p = 0.025),特异性分别为91.3%和88.4% (p = 0.16),正确诊断率分别为86.1%和88.1% (p = 0.26)。两种方法在1,201个额定动脉段的总体一致性非常好,为91.6%,kappa为0.80。口径较大的节段的一致性高于较小的节段:颞浅动脉共98.0%,枕动脉93.2%,额支89.8%,顶叶支86.9%。读者之间壁厚测量的相关性很强(Spearman’s rho为0.68)。施用T1-BB-VISUAL所需的时间约为T1-BB-COMP的一半(4.5分钟对8.95分钟)。结论:对于疑似GCA,在2D-T1-BB MRI中额外测量SCAs壁厚与单独的视觉半定量评分相比并不能带来更好的诊断效果。由于效率和可靠性较高,视觉评分是首选。
{"title":"2D-cranial T1-black-blood MRI in suspected giant cell arteritis-measurement of vessel wall thickness does not give a diagnostic advantage compared to visual scoring alone.","authors":"Pascal Seitz, Susana Bucher, Lukas Bütikofer, Britta Maurer, Harald Marcel Bonel, Fabian Lötscher, Luca Seitz","doi":"10.3389/fradi.2025.1597938","DOIUrl":"10.3389/fradi.2025.1597938","url":null,"abstract":"<p><strong>Objectives: </strong>To compare two established scoring schemes for the 2D-T1-weighted \"black-blood\" MRI sequence (T1-BB) for superficial cranial arteries (SCA) in the diagnosis of giant cell arteritis (GCA).</p><p><strong>Methods: </strong>Ten arterial segments were evaluated in T1-BB images with two different methods: a visual semiquantitative scheme (T1-BB-VISUAL) and a composite scheme that included both the semiquantitative assessment and a quantitative wall thickness measurement (T1-BB-COMP). The expert clinical diagnosis after ≥6 months of follow-up was the diagnostic reference standard. Diagnostic accuracy and agreement on the segment and patient levels were evaluated for the two different rating schemes.</p><p><strong>Results: </strong>Retrospectively, 151 consecutive patients with clinically suspected GCA were included. The study cohort consisted of 82 patients with and 69 without GCA. For the T1-BB-COMP and the T1-BB-VISUAL, the sensitivity was 81.7% vs. 87.8% (<i>p</i> = 0.025), the specificity was 91.3% vs. 88.4% (<i>p</i> = 0.16) and the proportion of correct diagnoses was 86.1% vs. 88.1% (<i>p</i> = 0.26), respectively. The overall agreement between the two methods for 1,201 rated arterial segments was very good at 91.6% with a kappa of 0.80. The agreement was higher for segments with a larger calibre than for smaller segments: common superficial temporal arteries 98.0%, occipital arteries 93.2%, frontal branches 89.8% and parietal branches 86.9%. The correlation of wall thickness measurements between readers was strong (Spearman's rho of 0.68). The time needed to apply the T1-BB-VISUAL was about half as long as for the T1-BB-COMP (4.5 vs. 8.95 minutes).</p><p><strong>Conclusion: </strong>In suspected GCA, the additional measurement of the wall thickness of SCAs in 2D-T1-BB MRI does not lead to a better diagnostic performance compared to visual semiquantitative scoring alone. Visual scoring is preferred due to higher efficiency and reliability.</p>","PeriodicalId":73101,"journal":{"name":"Frontiers in radiology","volume":"5 ","pages":"1597938"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Women in radiology: neuroimaging and neurotechnology. 社论:放射学中的女性:神经成像和神经技术。
Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1643898
Laura Elin Pigott, Katya Mileva, Laura Mancini
{"title":"Editorial: Women in radiology: neuroimaging and neurotechnology.","authors":"Laura Elin Pigott, Katya Mileva, Laura Mancini","doi":"10.3389/fradi.2025.1643898","DOIUrl":"10.3389/fradi.2025.1643898","url":null,"abstract":"","PeriodicalId":73101,"journal":{"name":"Frontiers in radiology","volume":"5 ","pages":"1643898"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal lesions: a comprehensive radiologic overview. 脊柱病变:综合放射学综述。
Pub Date : 2025-06-27 eCollection Date: 2025-01-01 DOI: 10.3389/fradi.2025.1577840
Zahin Alam, Mohammed Usman Syed, Tausif Ahmed Siddiqui, Aditya Gunturi, Brij Reddy, Zarah Alam, Akm A Rahman

Spinal lesions encompass a diverse range of pathologies, including primary and secondary tumors, infectious processes, vascular malformations, traumatic injuries, and degenerative conditions, each with distinct imaging characteristics crucial for accurate diagnosis and management. Imaging plays vital roles in assessing lesion morphology, anatomical localization, and neurological impact, guiding clinical decision-making and therapeutic planning. This review systematically explores spinal lesions based on their anatomical compartments, highlighting key radiological features and providing a comprehensive reference for radiologists.

脊柱病变包括多种病理,包括原发性和继发性肿瘤、感染性病变、血管畸形、创伤性损伤和退行性疾病,每一种病变都有不同的影像学特征,对准确诊断和治疗至关重要。影像学在评估病变形态、解剖定位和神经影响、指导临床决策和治疗计划方面发挥着重要作用。本综述系统地探讨了基于其解剖区室的脊柱病变,突出了关键的放射学特征,并为放射科医生提供了全面的参考。
{"title":"Spinal lesions: a comprehensive radiologic overview.","authors":"Zahin Alam, Mohammed Usman Syed, Tausif Ahmed Siddiqui, Aditya Gunturi, Brij Reddy, Zarah Alam, Akm A Rahman","doi":"10.3389/fradi.2025.1577840","DOIUrl":"10.3389/fradi.2025.1577840","url":null,"abstract":"<p><p>Spinal lesions encompass a diverse range of pathologies, including primary and secondary tumors, infectious processes, vascular malformations, traumatic injuries, and degenerative conditions, each with distinct imaging characteristics crucial for accurate diagnosis and management. Imaging plays vital roles in assessing lesion morphology, anatomical localization, and neurological impact, guiding clinical decision-making and therapeutic planning. This review systematically explores spinal lesions based on their anatomical compartments, highlighting key radiological features and providing a comprehensive reference for radiologists.</p>","PeriodicalId":73101,"journal":{"name":"Frontiers in radiology","volume":"5 ","pages":"1577840"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Frontiers in radiology
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