Acta Odontologica Scandinavica最新文献

Mandibular third molars (3M) are often associated with pathologies necessitating their surgical removal. Removal of 3M can cause injury to the inferior alveolar nerve (IAN). In coronectomy, a surgical option for 3M that present a significant risk of injury to the IAN, only the crown is removed, and the root/roots are left in situ, and may move after surgery. Methodology: A retrospective review was done to analyse the outcomes of coronectomy procedures performed at the Clinic of Oral and Maxillofacial Surgery, Institute of Clinical Odontology (IKO), University of Bergen (UiB) between 2014 and 2020. During this period, a total of 63 coronectomy procedures were performed. All 63 patients were contacted after approval from the regional ethical committee, and a total of 44 patients consented to participate in the study. Radiographic analysis was done based on panoramic radiographs (OPG), and patient records were analysed to assess which demographic and local factors were associated with root migration along with the number of post-operative complications. Results: Root migration was not associated with gender, root anatomy, or pattern of tooth impaction. Root migration was observed significantly more often in the younger age group, that is, ≤25 years. There were four reported cases of post-operative complications; two of those cases resolved with systemic antibiotics, while surgical intervention was necessary in the other two cases to remove the remaining roots. There were no reported cases of transient or permanent neurosensory disturbances.  Conclusion: Coronectomy is a viable technique to avoid nerve injury with 3M removal.

Objective: The relationship between orthodontic treatment and root resorption in endodontically treated teeth remains controversial. This systematic review and meta-analysis aimed to evaluate the effects of fixed appliance treatment on root resorption in root canal-treated teeth compared to vital teeth.

Methods: A comprehensive literature search was conducted across multiple databases including PubMed, Embase, Cochrane Library, Web of Science, Sinomed, CNKI, and Wanfang. Studies comparing root resorption between root canal-treated teeth and vital teeth during orthodontic treatment were included. The methodological quality was assessed using the Cochrane risk of bias tool. Standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated using random-effects models.

Results: Ten studies involving 266 patients met the inclusion criteria. The overall effect showed no significant difference in root resorption between root canal-treated teeth and vital teeth (SMD = -0.08, 95% CI: -0.24 to 0.08, I² = 7.0%). Subgroup analyses revealed no significant differences based on measurement methods, extraction versus non-extraction treatment, or tooth position. However, extraction cases demonstrated a numerical trend toward greater root resorption in root canal-treated teeth (SMD = -0.70, 95% CI: -1.50 to 0.11, I² = 67.1%, p = 0.048), while the non-extraction group showed no meaningful differences (SMD = -0.07, 95% CI: -0.42 to 0.28, I² = 49.2%, p = 0.096).

Conclusions: This meta-analysis suggests that root canal-treated teeth do not show significantly different root resorption patterns compared to vital teeth during orthodontic treatment. However, extraction cases may require careful monitoring due to a tendency toward increased root resorption.

Objectives: This paper studies the treatment effect of total joint replacement (TJR) of the temporomandibular joint (TMJ) with alloplastic joint prosthesis regarding function, symptoms and health-related quality of life compared to other surgical and non-surgical treatments in patients with TMJ disorders.

Methods: Three databases (PubMed, Cochrane Library and Web of Science) were searched up to 11 March 2025. Studies in which TJR was compared with other surgical or non-surgical methods were searched and analyzed. Data extraction and quality assessments were performed by at least two investigators independently. Risk of bias was assessed with the ROBINS-I-tool. Certainty of evidence was assessed with GRADE.

Results: A total of 2,891 studies were identified in the search. One study met the criteria with comparison of TJR with a control group consisting of patients treated with another surgical method, namely, interpositional arthroplasty. The study investigated the outcome variables such as pain reduction and improvement in mouth opening and had a moderate risk of bias. No significant difference between the groups was found after regression analysis. Quality of life assessment was not the objective of this study. No meta-analysis could be performed from this literature search, for obvious reasons.

Conclusion: TMJ reconstruction with alloplastic prostheses is rapidly evolving, with new systems continually entering the market. This review highlights the urgent need for further scientific efforts, including well-designed trials capable of demonstrating the comparative effectiveness of alloplastic TJR against other treatment modalities, ideally randomized trials with controls.

Objectives: Activation of sodium hypochlorite (NaOCl) to remove biofilm from lateral canal is important for the success of endodontic treatment. This study aimed to compare the biofilm dissolving capacity of different irrigation techniques in resin blocks with two lateral canals manufactured with 3D printers.  Materials and methods: Biofilm-mimicking hydrogel was placed in the upper and lower lateral canals of 75 resin blocks. Main canals of the blocks were irrigated with 5% NaOCl. Then, the blocks were randomly divided into five groups: sonic activation (SA), passive ultrasonic irrigation (PUI), intracanal heating (ICH), self-adjusting file (SAF) and control. The amount of hydrogel removed was measured by weighing the blocks before and after the treatment and further visually scored. Data were analyzed using Kruskall Wallis H, Wilcoxon, Tukey Post-hoc HSD (Honestly Significant Difference) and one-way ANOVA tests.

Results: The SAF group showed the highest hydrogel scores compared to other groups (p < 0.05). The hydrogel dissolution capacity of the SA group was lower compared to SAF, PUI and ICH techniques (p < 0.05). Based on visual scoring, SAF group was superior to other activation methods (p < 0.05) which are similar to each other (p > 0.05) in both upper and lower lateral canals.  Conclusion: All activation methods were superior than the control group. The SAF system demonstrated superior hydrogel dissolving ability, while SA, PUI, and ICH groups showed similar effectiveness.

Objective: Little was found on the association between diabetes and its effect on epithelial intercellular adhesion. However, no study reported the association between hyperglycemia and E-cadherin-mediated cell adhesion in tongue epithelium. This study aimed to explore the potential impacts of hyperglycemia on the epithelial E-cadherin expression in the tongue's epithelial tissue in streptozotocin (STZ)-induced diabetic rats.

Material and methods: Twelve male Wistar albino rats were randomly allocated into control and STZ-induced diabetic groups. At the 5-week post-STZ injection, rats were euthanized, and the tongues were harvested and preserved in formalin. Epithelial thickness was assessed using hematoxylin and eosin (H&E) staining, while immunohistochemistry (IHC) was employed to analyze the expression of E-cadherin. Statistical analysis was performed using unpaired t-tests and two-proportion Z-tests, with a significance level determined at p < 0.05.

Results: The results showed a significant reduction in epithelial thickness in the dorsal tongue of STZ-diabetic rats compared to the control group (p = 0.0173). Additionally, E-cadherin expression in the dorsal tongue epithelium was markedly weaker in the diabetic group than in the control (p < 0.0001).

Conclusions: This exploratory study is the first to report that hyperglycemia reduces E-cadherin expression in the dorsal tongue epithelium, possibly contributing to oral epithelial alterations observed in diabetes. These findings not only highlight the potential diagnostic value of E-cadherin as a biomarker for oral complications in diabetic patients but also provide a foundation for future translational and clinical studies exploring therapeutic interventions targeting epithelial integrity in diabetes.

Objectives: A previous questionnaire survey on infection control measures and infection status among practicing dentists during the 1st-5th surge of coronavirus disease 2019 (COVID-19) cases in Japan indicated a low risk of COVID-19 infection spreading through dental care. However, the low number of infected patients during the survey period may have been a contributing factor, and a sharp increase in the number of infected patients was subsequently observed. We re-examined the spread of infections in dental care settings and compared the results with those of previous reports.

Materials and methods: An online questionnaire-based survey was administered in March 2023 to examine the situation from February 2022 to March 2023, when the 6th-8th surge of COVID-19 infection was observed in Japan. The survey was conducted via an online platform (Google Forms; San Mateo, California, USA). The call for participation was publicized to members of the Nagano Dental Association. The survey consisted of questions on clinical activities, infection control measures, and confirmed or probable COVID-19 cases among patients and clinical staff.

Results: The number of COVID-19-positive patients increased approximately 50-fold between the study periods. There was a 3.5-fold increase in the rate of dental treatment for infected patients.

Conclusion: Even with the increased likelihood of contact with COVID-19 patients, no cases of infection during dental treatment were observed. The results of this study indicate that even with the possibility of contact with COVID-19 during dental treatment, the likelihood of COVID-19 clusters occurring in dental practices is low if appropriate infection prevention measures are in place.

Objective: Severe malocclusions affect Oral Health Related Quality of Life (OHRQoL), but the effects of less severe malocclusions are underexplored. This study investigates OHRQoL and psychological well-being in adults with less severe malocclusion, but high subjective need of orthodontic treatment.

Material and methods: This cross-sectional study included 130 study participants aged 18-75 years, with less severe malocclusion. Two groups were assessed: 65 with high subjective orthodontic treatment need and 65 in a control group. Patients with malocclusions graded with Index of Orthodontic Treatment Need-Dental Health Component (IOTN-DHC) index 1, 2, or 3 were included. Three questionnaires were used: Oral Health Impact Profile (OHIP-14), Hospital Anxiety and Depression Scale (HADS), and a general appearance perception survey.

Results: The high subjective need group showed significantly higher OHIP-14 scores, reflecting poorer OHRQoL, compared to the control group. When age was considered, only the orofacial appearance subscale remained significant. No clinical signs of depression or anxiety were found among participants. However, a subset in the high subjective need group spent over an hour daily on their oral appearance.

Conclusions: Adults seeking orthodontic treatment despite low objective treatment need may have impacted OHRQoL and an impairment from the time spent on their oral appearance. Dentist should consider patients' subjective treatment needs and impact on daily functioning when treating patients with mild malocclusions.

Objective: This study aimed to evaluate the effects of periodontal basic therapy combined with various adjunctive treatments on periodontal inflammation and glycemic control in patients with periodontitis and type 2 diabetes mellitus (T2DM) using network meta-analysis.

Methods: Randomized controlled trials (RCTs) involving patients with periodontitis and T2DM were retrieved from PubMed, Embase, Cochrane Library, and Web of Science up to February 29, 2024. The Cochrane quality scoring system was applied to assess study quality, and data were analyzed using R and Stata. The study was registered in PROSPERO (Registration No.: CRD42024501722).

Results: Thirty-seven RCTs involving 1,989 patients were included. Among the adjunctive therapies, scaling and root planing (SRP) with local satranidazole gel (SZ) achieved the best improvement in probing depth (PD) and clinical attachment level (CAL); SRP with systemic amoxicillin (AMX) significantly improved bleeding on probing (BOP); SRP with systemic doxycycline (Doxy) or antimicrobial photodynamic therapy (aPDT) was most effective for reducing glycated hemoglobin (HbA1c%); and SRP with diode laser (DL) improved fasting blood sugar (FBS) most effectively.

Conclusion: SRP combined with local SZ may improve PD and CAL in patients with periodontitis and T2DM. Systemic AMX may enhance BOP outcomes, while DOXY or aPDT may help reduce HbA1c. DL may contribute to better FBS improvement.

Objective: To investigate the relationship between self-perceived orthodontic treatment need, satisfaction with dental esthetics and occlusion, oral health-related quality of life (OHRQoL), occlusal deviations, and orthodontic treatment history of 17-year-olds.

Material and methods: Clinical examination and standardized questionnaire were completed by 108 adolescents from two municipal clinics. OHRQoL was measured with the Oral Health Impact Profile (OHIP-14) and malocclusion severity using the Peer Assessment Rating (PAR) Index. Associations between the variables were analyzed with Spearman's rank correlation and linear regression.

Results: Of the participants, 55% had either undergone orthodontic treatment or were in treatment. The level of self-perceived treatment need was low and satisfaction with esthetics and functionality of occlusion high. Painful aching in the mouth was the most reported OHIP item, followed by self-consciousness. Subjective treatment need and PAR correlated positively (rs(95) = 0.389, p < 0.001), whereas the OHIP score and PAR score showed no association. Subjective treatment need, satisfaction, or treatment history did not predict the OHIP score.

Conclusions: Majority of the adolescents were satisfied with their dental esthetics and occlusal function irrespective of past orthodontic treatment history. OHRQoL was poorer in adolescents with subjective orthodontic treatment need. Those with the greatest subjective treatment need had the most severe malocclusion.

Aim: The aim of this study is to classify accessory mandibular canals (AMC) and investigate their association with the dimensions of the mandibular canal (MC) to enhance surgical planning and prevent complications in dental treatments.

Methods: Cone-beam computed tomography (CBCT) images were evaluated. AMC's frequency, length, and diameter, including dental, superior, inferior, forward-open, forward-closed, and retromolar types, were determined. Additionally, the dimensions of the MC, including its length and diameter, were measured, and the relationship between the AMC and MC was statistically analyzed. Descriptive statistics, chi-square test, independent samples t-test (for normally distributed data), Kruskal-Wallis test (for non-normally distributed data), and Tamhane post hoc test were used for statistical analysis of the data.

Results: AMC was identified in 82 of the 222 hemimandibles examined (36.9%). It was found that the length and diameter of AMCs varied significantly depending on the AMC type (p = 0.000). The diameter of the dental type AMCs (mean 0.40 ± 0.22 mm) was considerably smaller than that of other AMC types (mean 0.86 ± 0.37 mm). The length and diameter of the MC were measured as 69.20 ± 5.10 mm and 2.96 ± 0.57 mm, respectively. While MC length was not found to influence the presence of AMC (p = 0.785), MC diameter was significantly associated with the occurrence of AMC (p = 0.000).

Conclusions: AMC, which is critical for improving surgical planning and reducing the risk of complications in dental procedures, is not uncommon. Their presence should be carefully evaluated, particularly in cases where the MC has a larger diameter.