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Efficient and Effective Diabetes Care in the Era of Digitalization and Hypercompetitive Research Culture: A Focused Review in the Western Pacific Region with Malaysia as a Case Study. 数字化和超竞争研究文化时代的高效和有效的糖尿病护理:西太平洋地区以马来西亚为例的重点回顾。
Pub Date : 2025-12-31 Epub Date: 2025-01-06 DOI: 10.1080/23288604.2024.2417788
Boon-How Chew, Pauline Siew Mei Lai, Dhashani A/P Sivaratnam, Nurul Iftida Basri, Geeta Appannah, Barakatun Nisak Mohd Yusof, Subashini C Thambiah, Zubaidah Nor Hanipah, Ping-Foo Wong, Li-Cheng Chang

There are approximately 220 million (about 12% regional prevalence) adults living with diabetes mellitus (DM) with its related complications, and morbidity knowingly or unconsciously in the Western Pacific Region (WP). The estimated healthcare cost in the WP and Malaysia was 240 billion USD and 1.0 billion USD in 2021 and 2017, respectively, with unmeasurable suffering and loss of health quality and economic productivity. This urgently calls for nothing less than concerted and preventive efforts from all stakeholders to invest in transforming healthcare professionals and reforming the healthcare system that prioritizes primary medical care setting, empowering allied health professionals, improvising health organization for the healthcare providers, improving health facilities and non-medical support for the people with DM. This article alludes to challenges in optimal diabetes care and proposes evidence-based initiatives over a 5-year period in a detailed roadmap to bring about dynamic and efficient healthcare services that are effective in managing people with DM using Malaysia as a case study for reference of other countries with similar backgrounds and issues. This includes a scanning on the landscape of clinical research in DM, dimensions and spectrum of research misconducts, possible common biases along the whole research process, key preventive strategies, implementation and limitations toward high-quality research. Lastly, digital medicine and how artificial intelligence could contribute to diabetes care and open science practices in research are also discussed.

在西太平洋地区(WP),大约有2.2亿(约12%的地区患病率)成年人患有糖尿病(DM)及其相关并发症,并有意或无意地发病。2021年和2017年,菲律宾和马来西亚的估计医疗成本分别为2400亿美元和10亿美元,造成了无法衡量的痛苦和卫生质量和经济生产力的损失。这迫切需要所有利益攸关方采取协调一致的预防措施,投资于转变医疗保健专业人员和改革医疗保健系统,优先考虑初级医疗保健设置,赋予专职医疗人员权力,为医疗保健提供者建立临时卫生组织,改善糖尿病患者的医疗设施和非医疗支持。本文暗示了最佳糖尿病护理方面的挑战,并在详细的5年路线图中提出了基于证据的倡议,以提供动态和高效的医疗服务,有效地管理糖尿病患者,并将马来西亚作为案例研究,以供其他具有类似背景和问题的国家参考。这包括对糖尿病临床研究概况的扫描,研究不当行为的维度和范围,整个研究过程中可能存在的共同偏见,关键的预防策略,实施和对高质量研究的限制。最后,还讨论了数字医学和人工智能如何有助于糖尿病护理和研究中的开放科学实践。
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引用次数: 0
Improving Implementation of NCD Care in Low- and Middle-Income Countries: The Case of Fixed Dose Combinations for Hypertension in Kenya.
Pub Date : 2025-12-31 Epub Date: 2025-02-04 DOI: 10.1080/23288604.2024.2448862
Adrianna Murphy, Daniel Mbuthia, Ruth Willis, Benjamin Tsofa, Mary Gichagua, Peter Mugo, Kara Hanson, Michael R Reich

Health systems in low- and middle-income countries face the challenge of addressing the growing burden of non-communicable diseases (NCDs) with scarce resources to do so. There are cost-effective interventions that can improve management of the most common NCDs, but many remain poorly implemented. One example is fixed dose combinations (FDCs) of medications for hypertension. Included in WHO's Essential Medicines List, FDCs combine two or more blood pressure lowering agents into one pill and can reduce burden on patients and the health system. However, implementation of FDCs globally is poor. We aimed to identify health systems factors affecting implementation of evidence-based interventions for NCDs, and opportunities to address these, using the case study of FDCs in Kenya. We conducted semi-structured interviews with 39 policy-makers and healthcare workers involved in hypertension treatment policy and identified through snowball sampling. Interview data were analyzed thematically, using the Access Framework to categorize themes. Our interviews identified factors operating at the global, national, county, and provider levels. These include lack of global implementation guidance, context specific cost-effectiveness data, or prioritization by procurement agencies and clinical guidelines; perceived high cost; poor data for demand forecasting; insufficient budget for procurement of NCD medications; absence of prescriber training and awareness of clinical guidelines; and habitual prescribing behavior and understaffing limiting capacity for change. We propose specific strategies to address these. The findings of this work can inform efforts to improve implementation of other evidence-based interventions for NCDs in low-income settings.

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引用次数: 0
Can a 19th Century French Medical Debate Provide Guidance on How to Tackle Type 2 Diabetes?
Pub Date : 2025-12-31 Epub Date: 2025-02-25 DOI: 10.1080/23288604.2025.2464977
Abdo S Yazbeck
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引用次数: 0
How Health Systems World-wide Fail Type 2 Diabetics.
Pub Date : 2025-12-31 Epub Date: 2025-01-23 DOI: 10.1080/23288604.2024.2437898
Abdo S Yazbeck, Son Nam Nguyen, Maria-Luisa Escobar

For over 50 years, health systems the world over have failed people with type 2 diabetes mellitus (T2DM). The WHO documents a quadrupling of people with diabetes in a 34-year period to 422 million in 2014, the overwhelming majority of whom were T2DM. This happened despite extensive scientific literature on the causes of, as well as proven treatments for, this disease. Using a health systems prism to review the extensive medical and nutritional T2DM published research, we identified three main shortcomings of health systems in T2DM: (i) failure in early detection; (ii) failure in understanding the actionable lifestyle drivers; and (iii) subsidizing the causes of the disease. Although small-scale success stories in T2DM control exist, the lack of documented evidence of any country-wide health system's successful attempt to address this epidemic is alarming. The immense and ever-growing health and economic burdens of T2DM should provide all the motivation needed for national and global efforts to counteract the political-economy constraints standing in the way of successful whole-of-system approaches to T2DM.

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引用次数: 0
Rethinking Trust and Public Health Compliance: Introducing a Trust Continuum for Policy and Practice.
Pub Date : 2025-12-31 Epub Date: 2025-02-11 DOI: 10.1080/23288604.2025.2457239
Ashley Fox, Victoria Y Fan, Heeun Kim, Minah Kang

Trust in government has emerged as one of the strongest predictors of national performance in fighting COVID-19. This commentary aims to take stock of the vast literature on trust and compliance with public health measures that has emerged during the pandemic to synthesize policy-relevant recommendations about: 1) How to conceptualize trust; 2) Whether trust is always deserved; and 3) How governments can earn (appropriate levels of) trust. Based on a critical reading of the literature, we develop a framework that conceptualizes trust as falling along a continuum ranging from extreme distrust to blind trust with the ideal point- "informed" or "basic" trust-falling in the mid-point of the continuum. We illustrate the continuum with examples and provide recommendations regarding how governments can build more nuanced disease responses that account for individuals and sub-groups at different rungs on the continuum while (re)building trust. We conclude that trust-building is a long-term project that must continue in non-crisis times.

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引用次数: 0
Resilience of Primary Health Care in Ukraine: Challenges of the Pandemic and War. 乌克兰初级卫生保健的复原力:大流行病和战争的挑战。
Pub Date : 2024-12-31 Epub Date: 2024-06-14 DOI: 10.1080/23288604.2024.2352885
Elina Dale, Julia Novak, Denys Dmytriiev, Olga Demeshko, Jarno Habicht

This commentary examines the resilience of primary health care in Ukraine amidst the ongoing war, drawing a few reflections relevant for other fragile and conflict-affected situations. Using personal observations and various published and unpublished reports, this article outlines five reflections on the strengths, challenges, and necessary adaptations of Primary Health Care (PHC) in Ukraine. It underscores the concerted efforts of the government to maintain public financing of PHC, thereby averting system collapse. The research also highlights the role of strategic adaptations during the COVID-19 pandemic in fostering resilience during the war, including the widespread use of digital communication and skills training. The commentary emphasizes the role of managerial and financial autonomy in facilitating quick and efficient organizational response to crisis. It also recognizes emerging challenges, including better access to PHC services among the internally displaced persons, shifting patient profiles and service needs, and challenges related to reliance on local government financing. Finally, the authors advocate for a coordinated approach in humanitarian response, recovery efforts, and development programs to ensure the sustainability and effectiveness of PHC in Ukraine.

这篇评论探讨了乌克兰初级卫生保健在持续战争中的恢复能力,并提出了一些与其他脆弱和受冲突影响局势相关的思考。通过个人观察以及各种已发表和未发表的报告,本文概述了对乌克兰初级卫生保健(PHC)的优势、挑战和必要调整的五点思考。文章强调了政府为维持初级卫生保健的公共筹资所做的共同努力,从而避免了系统的崩溃。研究还强调了在 COVID-19 大流行期间,战略调整在促进战争期间复原力方面的作用,包括广泛使用数字通信和技能培训。评论强调了管理和财务自主权在促进组织快速高效地应对危机方面的作用。评论还认识到了新出现的挑战,包括境内流离失所者更容易获得初级保健服务、病人情况和服务需求的变化以及与依赖地方政府融资有关的挑战。最后,作者主张在人道主义响应、恢复工作和发展计划中采用协调的方法,以确保乌克兰初级保健服务的可持续性和有效性。
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引用次数: 0
The Impact of Centralized Procurement on Treatment Patterns for Myocardial Infarction and More Principled Utilization of Coronary Stents. 集中采购对心肌梗塞治疗模式的影响以及冠状动脉支架的更合理利用。
Pub Date : 2024-12-31 Epub Date: 2024-06-21 DOI: 10.1080/23288604.2024.2366167
Weiyan Jian, Shanshan Huo, Lanyue Zhang, Wuping Zhou

Reducing the price of expensive medical products through centralized procurement is generally considered an effective way to save public medical resources. Against this background, this paper presents an analysis of the impact of centralized procurement in China by comparing the treatment costs and patterns for acute myocardial infarction (AMI) patients before and after the introduction of this method of purchasing, with specific reference to the use of coronary stents. We found that, after the implementation of centralized procurement for coronary stents, the total expenditure of AMI cases receiving percutaneous coronary interventions with stent implantation (PCI with stents) dropped by 23.4%. The use rate of PCI with stents decreased by 32.5%, with the most significant decrease being evident in cases in which two stents were used simultaneously (32.9%). Meanwhile, percutaneous coronary interventions with balloon implantation (PCI with balloons) increased by 31.5% and coronary artery bypass grafting (CABG) increased by 80.3%. Based on these patterns, it can be observed that the use of centralized procurement significantly reduced the profits of the relevant medical manufacturers, forcing them to decrease their marketing investments, weakening their influence on providers, and ultimately resulting in a more principled use of coronary stents. We therefore conclude that, with reference to the data cited, the centralized procurement program led not only to a reduction in procurement prices but also to decreased overuse of these expensive medical products.

通过集中采购降低昂贵医疗产品的价格被普遍认为是节约公共医疗资源的有效途径。在此背景下,本文通过比较集中采购前后急性心肌梗死(AMI)患者的治疗费用和模式,特别是冠状动脉支架的使用情况,分析了集中采购在中国的影响。我们发现,在实施冠状动脉支架集中采购后,接受经皮冠状动脉介入治疗并植入支架(PCI with stents)的急性心肌梗死病例的总支出下降了 23.4%。植入支架的经皮冠状动脉介入治疗的使用率下降了 32.5%,其中同时使用两个支架的病例下降最为明显(32.9%)。同时,球囊植入经皮冠状动脉介入治疗(PCI with balloons)增加了 31.5%,冠状动脉旁路移植术(CABG)增加了 80.3%。根据这些模式可以看出,集中采购的使用大大降低了相关医疗制造商的利润,迫使他们减少营销投入,削弱了他们对医疗服务提供者的影响力,最终导致冠状动脉支架的使用更加原则化。因此,我们得出结论,根据所引用的数据,集中采购计划不仅降低了采购价格,还减少了这些昂贵医疗产品的过度使用。
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引用次数: 0
Does Public Financial Management Save Life? Evidence from a Quantitative Review of PFM and Health Outcomes in Sub-Saharan African Countries. 公共财政管理能拯救生命吗?对撒哈拉以南非洲国家公共财政管理和卫生成果的定量研究证据。
Pub Date : 2024-12-31 Epub Date: 2024-01-15 DOI: 10.1080/23288604.2023.2298190
Yann Tapsoba, Amna Silim, Kingsley Addai Frimpong, Hélène Barroy

Public financial management (PFM) theory suggests that improvements in the allocation, execution, and monitoring of public funds can result in improved sectoral outcomes, including in health. However, the existing literature on the relationship between PFM quality and health outcomes provides limited empirical documentation and insufficient explanation of the mechanics of that relationship. This paper contributes to the literature by estimating the correlation between PFM quality and health outcomes from a sample of sub-Saharan African countries over the period 2005-2018, using a pooled ordinary least squares (OLS) estimator. The analysis uses Public Expenditure and Financial Accountability (PEFA) scores as proxies for PFM quality. The findings indicate that countries with high-quality PFM tended to have the lowest maternal, under-five and noncommunicable diseases (NCDs) mortality. Among the standard PFM dimensions, the one associated with the higher correlation with maternal and under-five mortality was "predictability and control in budget execution." Better PFM quality was significantly associated with a drop in maternal and under-five mortality in countries which allocated a higher proportion of their budget to the health sector. In countries allocating a lower proportion of their budget to health, the correlations between PFM quality and the three mortality indicators were not significant. The negative correlations between PFM quality and maternal and under-five mortality were significant only in countries with more effective governance. These findings support an emphasis on strengthening PFM as a means of improving health service provision and health outcomes.

公共财政管理(PFM)理论认为,改善公共资金的分配、执行和监督可以改善部门成果,包括卫生部门的成果。然而,关于公共财政管理质量与卫生成果之间关系的现有文献提供的经验文献有限,对这种关系的机制解释不足。本文采用集合普通最小二乘法(OLS)估计方法,对 2005-2018 年期间撒哈拉以南非洲国家样本中的公共财政管理质量与卫生成果之间的相关性进行了估计,为相关文献做出了贡献。分析使用公共支出和财务问责(PEFA)得分作为公共财政管理质量的替代指标。研究结果表明,公共财政管理质量高的国家的孕产妇、五岁以下儿童和非传染性疾病(NCDs)死亡率往往最低。在标准的 PFM 维度中,与孕产妇和五岁以下儿童死亡率相关性较高的是 "预算执行的可预测性和控制"。在将较高比例的预算分配给卫生部门的国家中,较高的 PFM 质量与孕产妇和五岁以下儿童死亡率的下降有很大关系。在卫生部门预算拨款比例较低的国家,PFM 质量与三项死亡率指标之间的相关性并不显著。只有在治理更有效的国家,公共财政管理质量与孕产妇和五岁以下儿童死亡率之间的负相关关系才显著。这些研究结果支持将重点放在加强 PFM 上,将其作为改善保健服务提供和保健成果的一种手段。
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引用次数: 0
COVID-19 Deaths in Long-Term Care Facilities in the US: An Urgent Call for Equitable and Integrated Health Systems and an All-Hazards Approach to the Next Crisis. COVID-19 美国长期护理机构中的死亡案例:紧急呼吁建立公平、综合的医疗系统,并采用全危险方法应对下一次危机。
Pub Date : 2024-12-31 Epub Date: 2024-01-29 DOI: 10.1080/23288604.2023.2298652
Eriko Sase, Christopher Eddy, Richard J Schuster
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引用次数: 0
Assessing Root Causes and Solutions to Address Cross-Programmatic Inefficiencies in a Subnational Health System: A Case Study of Anambra State, Nigeria. 评估地方卫生系统跨规划效率低下的根本原因和解决方案:尼日利亚阿南布拉州的案例研究。
Pub Date : 2024-12-18 Epub Date: 2025-01-08 DOI: 10.1080/23288604.2024.2441533
Obinna Onwujekwe, Uchenna Ezenwaka, Prince Agwu, Chukwudi Nwokolo, Francis Ukwuije, Alexandra J Earle, Agnes Gatome-Munyua, Susan Sparkes

Cross-programmatic inefficiencies are duplications or misalignments that arise from undue fragmentation of health systems by vertical health programs. Identifying and addressing the root causes of cross-programmatic inefficiencies in a health system can ensure more efficient use of resources to make progress toward Universal Health Coverage. This paper examines the root causes of cross-programmatic inefficiencies related to governance and financing in the state health system of Anambra in southeast Nigeria. Data were collected from 38 in-depth interviews and four focus group discussions and analyzed thematically. The governance- and finance-related cross-programmatic inefficiencies identified were duplicative and misaligned roles within and between state and federal agencies, functions, and activities within and across health programs; misaligned donor priorities with that of the state; and poor formulation and implementation of the approved annual state health budget. The root causes of governance and financing cross-programmatic inefficiencies included weak policy development, communication, and enforcement; excessive influence of external donors and the federal government; weak accountability mechanisms affecting program coordination and service delivery; and a disharmony between state priorities and objectives with planning, budgeting, and execution of the budget. Addressing the root causes of cross-programmatic inefficiencies has the potential to significantly improve the overall efficiency and performance of the health system to contribute to improved health outcomes in Anambra state. This approach can serve as a model for other states and regions facing similar challenges.

跨规划效率低下是由于垂直卫生规划对卫生系统的过度分散而造成的重复或不一致。查明和解决卫生系统跨规划效率低下的根本原因,可确保更有效地利用资源,在实现全民健康覆盖方面取得进展。本文考察了尼日利亚东南部阿南布拉州卫生系统中与治理和融资相关的跨规划效率低下的根本原因。通过38次深度访谈和4次焦点小组讨论收集数据并进行主题分析。所确定的与治理和财务相关的跨规划效率低下是州和联邦机构内部和之间的重复和不一致的角色,以及卫生项目内部和跨卫生项目的职能和活动;捐赠优先事项与国家优先事项不一致;批准的年度国家卫生预算制定和执行不力。治理和融资跨规划效率低下的根本原因包括政策制定、沟通和执行不力;外部捐助者和联邦政府的过度影响;影响方案协调和服务提供的问责机制薄弱;国家优先事项和目标与计划、预算和预算执行之间的不协调。解决跨规划效率低下的根本原因有可能显著提高卫生系统的整体效率和绩效,从而有助于改善阿南布拉州的卫生结果。这种方法可以作为其他面临类似挑战的州和地区的典范。
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引用次数: 0
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Health systems and reform
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