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Potential use of faecal sludge derived char briquettes as an alternative cooking energy source in Dar es Salaam, Tanzania 在坦桑尼亚达累斯萨拉姆,粪便污泥衍生炭块作为替代烹饪能源的潜在用途
Pub Date : 2023-09-01 DOI: 10.1016/j.heha.2023.100068
Petro Mwamlima , Aloyce W. Mayo , Sara Gabrielsson , Richard Kimwaga

Coprophobia characterizes faecal sludge (FS) as an unpleasing raw or partially digested faecal waste with no recycling value. However, this so-called waste is claimed to have tremendous recycling values after being pyrolyzed. This study hypothesized that char briquettes made from FS might have the potential of replacing charcoal consumption in Dar es Salaam, Tanzania. Quantitative methods were used to examine the proximate, emissions and environmental benefits of faecal sludge char briquettes in comparison to wood charcoal from Dalbergia melanoxylon (locally known as Mpingo). Results revealed that FS collected during the dry season exhibited a higher total solids content (26%) compared to that collected during the rainy season (20%). This difference was statistically significant (p = 6.12405E-14 at α=0.05). Dewatering and further drying the FS to a minimum of 90% total solids yielded an energy value of 11-12 MJ/kg, which was lower than that of uncarbonized wood (firewood) at 19 MJ/kg. Production of FS char briquettes bonded by paper waste has a lower energy value (13 MJ/kg) than that bonded by cassava starch (14.6 MJ/kg). The average energy value of FS char briquettes is almost half that of wood charcoal (26 MJ/kg), meaning that the replacement of 1 kg of charcoal consumption would require 2 kg of FS char briquettes is required. Nevertheless, due to an ineffective collection of FS to be used in the production of char briquettes, only 8% of charcoal consumption in the city can be replaced. It is recommended to use the produced briquettes in open kitchens with ample oxygen circulation, as they emit carbon monoxide levels exceeding the allowable limits set by the Tanzania Bureau of Standards.

粪泥恐惧症的特点是粪便污泥是一种令人讨厌的未经处理或部分消化的粪便废物,没有回收价值。然而,这种所谓的废物在被热解后据称具有巨大的回收价值。这项研究假设,在坦桑尼亚达累斯萨拉姆,由FS制成的炭块可能有取代木炭消费的潜力。采用定量方法,比较了粪便污泥炭型煤与黑檀(当地称为Mpingo)木炭的近因、排放和环境效益。结果表明,旱季收集的FS总固体含量(26%)高于雨季收集的FS(20%)。差异有统计学意义(p = 6.12405E-14, α=0.05)。将FS脱水并进一步干燥至至少90%的总固体,其能量值为11-12 MJ/kg,低于未碳化木材(木柴)的19 MJ/kg。造纸废弃物黏结FS型煤的能量值(13 MJ/kg)低于木薯淀粉黏结FS型煤的能量值(14.6 MJ/kg)。FS型煤的平均能量值几乎是木质木炭的一半(26兆焦耳/公斤),这意味着每消耗1公斤木炭,就需要消耗2公斤FS型煤。然而,由于无法有效收集用于生产炭型煤的FS,该市只有8%的木炭消耗量可以被替代。建议在氧气流通充足的开放式厨房中使用生产的压块,因为它们排放的一氧化碳含量超过了坦桑尼亚标准局规定的允许限值。
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引用次数: 0
Let smart wearable-generated health data speak for elders 让智能可穿戴设备生成的健康数据为老年人说话
Pub Date : 2023-09-01 DOI: 10.1016/j.heha.2023.100069
Chengjun Li , Huan Zhong , Mengjie Wu , Xiliang Yan , Christian Sonne
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引用次数: 0
The influence of environmental conditions and hypochlorous acid (HOCl) fogging on the infectivity of H1N1 influenza virus 环境条件和次氯酸(HOCl)雾化对H1N1流感病毒传染性的影响
Pub Date : 2023-08-30 DOI: 10.1016/j.heha.2023.100077
Kuan-Che Feng , Haijiao Liu , Anish Ghai , Juyi Li , Huiting Luo , Won-Il Lee , Steffen Mueller , Jerome Cymerman , Marcia Simon , Miriam Rafailovich

The influence of different environmental factors on the infectivity of H1N1 influenza virus was measured. We found less than 1-log reduction when viruses were exposed to NaCl solutions up to 5 M or solutions with pH = 4 through 11 for one hour. The infectivity of the virus was sensitive to the solution temperature. A log reduction ranging from 2 to more than 6 was observed starting at 50 °C and spanning just 3 or 5 for 10- or 30 min exposures, respectively. Drying the virus in media on aluminum or polymer coupons for 48 h resulted in a log reduction of 4 when kept at room temperature, but less than one when kept at 4 °C or -20 °C. Log reduction greater than 6 occurred at room temperature after 3 days, but only 1-log reduction occurred at 4 and -20 °C after 6 days. Drying on different coinage achieved similar results, except for pennies, where more than 6-log reduction was observed after 24 h. HOCl was used to fog the aluminum and polymer surfaces, placed vertically, for 5 and 7.5 min to achieve a log reduction of 4 and for 6.5 respectively. Storage of opened solution containers for 9 months at ambient resulted in a decrease in chlorine concentration from 550 ppm to 240 ppm. Fogging with the old solution was still able to achieve a log reduction of 6.5 after 7.5 min fogging. The study indicates that exposure to common environmental conditions such as a wide pH range, high salinity, and low temperatures has only a minor effect on infectivity. which can persist for more than 5 days when dried on commonly encountered surfaces, allowing accumulation of infectious viral titre. Fogging with HOCl is an effective method of delivering disinfectants to large areas, achieving complete reduction of the viral titer on both horizontal and vertical surfaces.

测定了不同环境因素对H1N1流感病毒传染性的影响。我们发现,当病毒暴露在高达5 M的NaCl溶液或pH = 4至11的溶液中一小时时,其降低幅度小于1对数。病毒的传染性对溶液温度敏感。从50°C开始观察到2到6以上的对数减少,分别在10或30分钟的暴露中仅跨越3或5。将病毒在铝或聚合物薄片上的介质中干燥48小时,室温下的对数减少4,但在4°C或-20°C下的对数减少不到1。3天后,室温下的对数减少量大于6,但6天后,在4°C和-20°C下的对数减少量仅为1。在不同的铸币上干燥取得了类似的结果,除了硬币,在24小时后观察到超过6倍的减少。HOCl用于雾化铝和聚合物表面,垂直放置5和7.5分钟,分别达到4和6.5倍的对数减少。打开的溶液容器在环境下储存9个月导致氯浓度从550 ppm降至240 ppm。在雾化7.5分钟后,使用旧溶液雾化仍然能够实现6.5的日志减少。该研究表明,暴露在常见的环境条件下,如宽pH范围、高盐度和低温,对传染性的影响很小。当在常见的表面干燥时,可持续5天以上,使传染性病毒滴度积累。用HOCl雾化是向大面积输送消毒剂的有效方法,可以在水平和垂直表面上完全降低病毒滴度。
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引用次数: 0
Iron- and protein rich diets may boost hemoglobin levels among informal electronic waste recyclers exposed to metals at Agbogbloshie, Ghana 在加纳阿博布罗西,富含铁和蛋白质的饮食可能会提高接触金属的非正式电子废物回收者的血红蛋白水平
Pub Date : 2023-07-10 DOI: 10.1016/j.heha.2023.100073
Sylvia A. Takyi , John Arko-Mensah , Niladri Basu , Serwaa Bawuah , Duah Dwomoh , Julius N. Fobil

While human exposure to metals may play a role in the pathogenesis of anemia, consumption of balanced diets may boost blood hemoglobin (Hb) levels in humans. Although informal electronic waste (e-waste) recycling processes have recently drawn attention as an important source of pollution, there is almost no empirical evidence on the relationship between diet, metals exposure and anemia among e-waste recyclers. Therefore, we evaluated possible ameliorating effects of diet on metal exposure related anemia, as measured by Hb levels of e-waste recyclers and a reference population in Ghana.

This repeated measure study used data collected from e-waste recyclers (n=142) and a reference population (n=65) between March 2017 and October 2018. Stored whole blood samples were analyzed for the following metals; Cd, Pb, Rb, Tb, Tl, and Eu. Next, Hb levels were analysed using the URIT-810® semiautomatic biochemistry analyzer. Furthermore, a 48-hour dietary recall questionnaire was administered to assess dietary intake parameters such as protein, folate, carbohydrates, Fe, Ca, Mg, Se, Zn, and Cu. Ordinary regression models were used to estimate joint effects of metals and nutrients on Hb levels.

At baseline, the mean Hb was lower among recyclers (12.99 ± 3.17 g/dL) than the reference group (13.02±2.37 g/dL). Blood Pb, Cd, Rb, Eu and Tb were associated with significant decreases in Hb levels of e-waste recyclers. Dietary intake of proteins and Fe was associated with concomitant increase in Hb levels of both groups as well as when analysis was restricted to recyclers. Despite the high exposure of e-waste recyclers to a myriad of metals, consumption of Fe-rich diets appears to ameliorate anemia and improved Hb levels (β=0.229; 95% CI: 0.013, 0.445; p=0.04). Therefore, the consumption of Fe and protein-rich foods may boost blood Hb levels in e-waste recyclers, even though exposure to high levels of metals is a predictor of anemia among this worker-group.

虽然人体接触金属可能在贫血的发病机制中起作用,但均衡饮食可能会提高人体的血红蛋白(Hb)水平。尽管非正式的电子废物(电子废物)回收过程最近作为一个重要的污染源引起了人们的注意,但几乎没有关于电子废物回收者饮食、金属接触和贫血之间关系的经验证据。因此,我们评估了饮食对金属暴露相关贫血的可能改善作用,通过加纳电子垃圾回收者和参考人群的Hb水平来测量。这项重复测量研究使用了2017年3月至2018年10月期间从电子垃圾回收者(n=142)和参考人群(n=65)收集的数据。对储存的全血样本进行了以下金属分析;Cd, Pb, Rb, Tb, Tl和Eu。接下来,使用URIT-810®半自动生化分析仪分析Hb水平。此外,采用48小时膳食回忆问卷来评估膳食摄入参数,如蛋白质、叶酸、碳水化合物、铁、钙、镁、硒、锌和铜。普通回归模型用于估计金属和营养物质对血红蛋白水平的共同影响。在基线时,回收者的平均Hb(12.99±3.17 g/dL)低于对照组(13.02±2.37 g/dL)。血液中的Pb、Cd、Rb、Eu和Tb与电子垃圾回收者Hb水平的显著下降有关。饮食中蛋白质和铁的摄入与两组Hb水平的增加有关,当分析仅限于回收者时也是如此。尽管电子垃圾回收者大量接触金属,但食用富含铁的饮食似乎可以改善贫血和Hb水平(β=0.229;95% ci: 0.013, 0.445;p = 0.04)。因此,摄入铁和富含蛋白质的食物可能会提高电子垃圾回收者血液中的Hb水平,尽管接触高水平的金属是这一工人群体贫血的前兆。
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引用次数: 0
Atmospheric halogenated hydrocarbons emitted from a flame retardant production base and the influence on ozone formation potential and health risks 阻燃剂生产基地排放的大气卤代烃及其对臭氧形成潜力和健康风险的影响
Pub Date : 2023-07-02 DOI: 10.1016/j.heha.2023.100070
Qinhao Lin , Wei Kang , Shuo Lin , Yingxin Yu , Taicheng An

The flame retardant industrial park is a significant source of atmospheric volatile organic compound (VOC) emissions. A flame retardant factory is generally associated with abundant salt pans, which facilitate brine raw materials for flame retardant production. However, the concentrations and compositions of these VOCs from the factories and the surrounding salt pans are still unclear. Therefore, this study characterized the VOCs from various production areas in a flame retardants factory and its surrounding salt pans. We investigated five VOC types: alkanes, aromatic hydrocarbons (AHs), halogenated hydrocarbons (HHs), halogenated aromatic hydrocarbons, and halogenated olefin. AHs (41.0 ± 26.3 µg/m3) were the dominant VOC type in the factory, followed by HHs (7.64 ± 6.52 µg/m3). As for the surrounding salt pans, HHs (89.6 ± 55.9 µg/m3), followed by AHs (20.9 ± 13.8 µg/m3). Generally, HHs and AHs were found to be potential cancer risks, especially 1,2-dichlorothane, 1,2-trichlorothane, and benzene. Furthermore, the diffusion of AHs or HHs from the study areas may affect the local residential area and school. AHs were the study region's most significant contributor to ozone formation potential. Consequently, this study provides detailed characteristics of VOCs in flame retardant industrial parks and contributes to developing targeted control strategies.

阻燃工业园区是大气挥发性有机化合物(VOC)排放的重要来源。一个阻燃工厂通常与丰富的盐田相关联,这为生产阻燃剂提供了卤水原料。然而,来自工厂和周围盐田的这些挥发性有机化合物的浓度和成分仍然不清楚。因此,本研究对某阻燃剂厂及其周边盐田各生产区域的挥发性有机化合物进行了表征。我们研究了五种VOC类型:烷烃、芳烃(AHs)、卤代烃(HHs)、卤代芳烃和卤代烯烃。挥发性有机化合物以AHs(41.0±26.3µg/m3)为主,其次为hs(7.64±6.52µg/m3)。周边盐田HHs(89.6±55.9µg/m3)次之,AHs(20.9±13.8µg/m3);一般来说,HHs和AHs被发现是潜在的癌症风险,特别是1,2-二氯烷、1,2-三氯烷和苯。此外,来自研究区域的AHs或HHs扩散可能会影响当地的居民区和学校。AHs是研究区域臭氧形成潜力的最重要贡献者。因此,本研究提供了阻燃工业园区VOCs的详细特征,有助于制定有针对性的控制策略。
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引用次数: 0
A Driving Force-Pressure-State-Impact-Response (DPSIR) tool to help waste pickers' cooperatives self-evaluate their environmental and economic performance 一个驱动力-压力-状态-影响-响应(DPSIR)工具,帮助拾荒合作社自我评估其环境和经济绩效
Pub Date : 2023-06-01 DOI: 10.1016/j.heha.2023.100054
Jéssica Patrícia Corrêa Brunhara , Karla Gonçalves Macedo , Tapas K. Das , Murilo Daniel de Mello Innocentini

Cooperatives of waste pickers play a critical role in municipal solid waste management, contributing to public health, sanitation, and the environment by promoting resource circulation and reducing the amount of recyclable waste disposed of in landfills. Despite this, the majority of cooperatives lack an organized physical infrastructure and operational protocols for integrated waste management, which includes the stages of sorting, classification, processing, and marketing recyclable waste. In this work, an optimized survey was developed to assist waste pickers’ cooperatives in self-assessing their social, environmental, and economic performances. A questionnaire with nine dimensions was developed and automated to connect 16 driving forces (D), 74 pressure indicators (P), 23 states (S), 35 impacts (I), and 38 responses (R). The only action required was to choose each pressure indicator and apply the appropriate score level based on the cooperative's data analysis. The procedure eliminates subjective interpretation and identifies all indicators that require further consideration and discussion. As a result, the cooperative is able to propose highly targeted improvement measures. To demonstrate the benefits of the tool, the survey was applied in a waste picker's cooperative in a municipality in Brazil.

拾取废物合作社在城市固体废物管理方面发挥着关键作用,通过促进资源循环和减少在垃圾填埋场处置的可回收废物的数量,为公共健康、卫生和环境作出贡献。尽管如此,大多数合作社缺乏有组织的物质基础设施和综合废物管理的操作规程,其中包括分类、分类、处理和销售可回收废物的各个阶段。在这项工作中,开发了一项优化的调查,以帮助拾荒者合作社自我评估其社会、环境和经济绩效。开发并自动化了一份包含9个维度的问卷,将16个驱动力(D)、74个压力指标(P)、23个状态(S)、35个影响(I)和38个响应(R)联系起来。唯一需要做的就是选择每个压力指标,并根据合作社的数据分析应用适当的评分水平。该程序消除了主观解释,并确定了需要进一步考虑和讨论的所有指标。因此,合作社能够提出高度针对性的改进措施。为了证明该工具的好处,该调查在巴西一个城市的一个拾取垃圾的合作社中应用。
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引用次数: 1
First report on occurrence of heavy metals in dried fishes from major fishing villages in Kerala coast, Southwest India 印度西南部喀拉拉邦主要渔村干鱼中重金属含量的首次报告
Pub Date : 2023-06-01 DOI: 10.1016/j.heha.2023.100051
Pyary Anisha , Pulickal Santhosh Athira , Biju Anagha , Partheeban Emmanuel Charles , Krishnamurthy Prabakaran , Rajendran Rajaram

Heavy metal concentrations in dried fishes collected from four fishing villages of Kerala, India, have been assessed using atomic absorption spectrophotometry. Overall, metal concentrations in dry fishes were in the decreasing order: Zn>Pb>Cu>Cr>Cd. Except Pb and Cr, other metals assessed were within permissible limits. Higher accumulation of Pb may be attributed to anthropogenic sources of metals that are persistent in the southwest coast of India, especially the Kerala coast, due to extensive industrialization, urbanization, fishing and port activities. Thirty-six species of dried fishes collected from Azhikode and Munambam zones were found to have more metal accumulations. The metal pollution assessment of dried fishes indicated that Pb and Cr concentrations are higher in the Kerala coast. Further studies must be carried out in more dried fish species and other preserved seafood to ensure that the dried fishes processed from these polluted coastal zones do not cause any harm to the consumers.

采用原子吸收分光光度法对从印度喀拉拉邦四个渔村收集的干鱼中的重金属浓度进行了评估。总体而言,干鱼体内的金属浓度依次递减:Zn>Pb>Cu>除铅、铬外,其他金属均在允许范围内。由于广泛的工业化、城市化、渔业和港口活动,印度西南海岸,特别是喀拉拉邦海岸的人为金属来源持续存在,可能导致铅积累较高。在Azhikode和Munambam地区收集的36种干鱼中发现了更多的金属积累。鱼干的金属污染评价表明,喀拉拉邦沿海地区Pb、Cr浓度较高。必须对更多种类的干鱼和其他腌制海鲜进行进一步的研究,以确保从这些受污染的沿海地区加工的干鱼不会对消费者造成任何伤害。
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引用次数: 1
Assessment of health and economic benefits of reducing fine particulate matter (PM2.5) concentration in Ho Chi Minh City, Vietnam 越南胡志明市减少细颗粒物(PM2.5)浓度的健康和经济效益评估
Pub Date : 2023-06-01 DOI: 10.1016/j.heha.2023.100045
Tinh Huu Ho , Chinh Van Dang , Thao Thi Bich Pham , Supat Wangwongwatana

Ambient fine particulate matter (PM2.5) is a growing issue in Ho Chi Minh City (HCMC), the most populous province in Viet Nam. Estimating the benefits of reducing PM2.5 levels has still been sparse in HCMC.

The study used the Environmental Benefits Mapping and Analysis Program – Community Edition (BenMAP-CE) to estimate the health, and economic benefits in three controlling scenarios of annual average PM2.5 concentration in 2019 (28.9 µg/m3) rolling back to the World Health Organization's annual average Air Quality Guideline values of 5 µg/m3 (guideline value in 2021), and 10 µg/m3 (guideline value in 2005 which becomes Interim Target 4 of 2021 WHO Air Quality Guideline), and the Vietnamese annual average standard of 25 µg/m3.

The annual average concentration of PM2.5 in 2019 was 28.9 µg/m3. Applying BenMAP-CE, the pooled number of avoided deaths of all causes was 3,785 (1,179–6,335), 3,195 (982–5,468), and 1,300 (384–2,386) for three scenarios, respectively. The economic benefits were $ 2.4 (0.8–4.1), $ 2.1 (0.6–3.5), and $ 0.8 (0.2–1.5) billion, using the Value of Statistical Life (VSL) of OECD (the Organization for Economic Cooperation and Development) and $ 3.7 (1.2–6.2), $ 3.1 (1.0–5.4) and $ 1.3 (0.4–2.3) billion, using the VSL of USEPA (the United States Environmental Protection Agency).

The annual average PM2.5 concentration in HCMC exceeded the Vietnamese standard and WHO guidelines. Controlling PM2.5 showed massive benefits for health and the economy; thus, the city should have action plans for mitigating the PM2.5 pollution.

在越南人口最多的省份胡志明市,环境细颗粒物(PM2.5)是一个日益严重的问题。在胡志明市,对降低PM2.5水平的好处的估计仍然很少。该研究使用环境效益制图和分析程序-社区版(BenMAP-CE)估算了2019年年均PM2.5浓度(28.9微克/立方米)降至世界卫生组织的年平均空气质量指南值5微克/立方米(2021年的指导值)和10微克/立方米(2005年的指导值,成为2021年世卫组织空气质量指南的中期目标4)的三种控制情景下的健康和经济效益。越南年平均标准为25µg/m3。2019年PM2.5年平均浓度为28.9µg/m3。应用BenMAP-CE,在三种情况下,避免所有原因死亡的总人数分别为3,785(1,179-6,335),3,195(982-5,468)和1,300(384-2,386)。使用经济合作与发展组织(OECD)的统计寿命值(VSL),经济效益分别为2.4亿美元(0.8 - 4.1亿美元)、2.1亿美元(0.6-3.5亿美元)和0.8亿美元(2 - 15亿美元);使用美国环境保护署(USEPA)的统计寿命值(VSL),经济效益分别为3.7亿美元(1.2-6.2亿美元)、3.1亿美元(1.0-5.4亿美元)和13亿美元(0.4 - 23亿美元)。胡志明市的年平均PM2.5浓度超过越南标准和世界卫生组织的指导方针。控制PM2.5对健康和经济都有巨大的好处;因此,城市应该制定减缓PM2.5污染的行动计划。
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引用次数: 1
Personal protective equipment and micro-nano plastics: A review of an unavoidable interrelation for a global well-being hazard 个人防护设备和微纳米塑料:对全球福祉危害不可避免的相互关系的回顾
Pub Date : 2023-06-01 DOI: 10.1016/j.heha.2023.100055
Shaheen Akhtar , Kumar Pranay , Kanchan Kumari

The usage and the demand for personal protective equipments (PPEs) for our day-to-day survival in this pandemic period of COVID-19 have seen a steep rise which has consequently led to improper disposal and littering. Fragmentation of these PPE units has eventually given way to micro-nano plastics (MNPs) emission in the various environmental matrices and exposure of living organisms to these MNPs has proven to be severely toxic. Numerous factors contribute to the toxicity imparted by these MNPs that mainly include their shape, size, functional groups and their chemical diversity. Even though multiple studies on the impacts of MNPs toxicity are available for other organisms, human cell line studies for various plastic polymers, other than the most common ones namely polyethylene (PE), polystyrene (PS) and polypropylene (PP), are still at their nascent stage and need to be explored more. In this article, we cover a concise review of the literature on the impact of these MNPs in biotic and human systems focusing on the constituents of the PPE units and the additives that are essentially used for their manufacturing. This review will subsequently identify the need to gather scientific evidence at the smaller level to help combat this microplastic pollution and induce a more in-depth understanding of its adverse effect on our existence.

在新冠肺炎大流行期间,日常生存所需的个人防护装备的使用量和需求量急剧增加,导致处置不当和乱扔垃圾。这些个人防护装备的碎片最终在各种环境基质中被微纳塑料(MNPs)排放所取代,生物体暴露于这些MNPs已被证明具有严重毒性。许多因素导致这些MNPs的毒性,主要包括它们的形状、大小、官能团和化学多样性。尽管对MNPs毒性对其他生物体的影响进行了多项研究,但除了最常见的聚乙烯(PE)、聚苯乙烯(PS)和聚丙烯(PP)外,对各种塑料聚合物的人体细胞系研究仍处于起步阶段,需要进行更多的探索。在本文中,我们简要回顾了关于这些MNPs对生物和人类系统影响的文献,重点是PPE单元的成分和主要用于其制造的添加剂。随后的审查将确定需要在较小的层面上收集科学证据,以帮助对抗这种微塑料污染,并更深入地了解其对我们生存的不利影响。
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引用次数: 1
Epidemiology for risk assessment: The US Environmental Protection Agency quality considerations and the Matrix 流行病学风险评估:美国环境保护署质量考虑和矩阵
Pub Date : 2023-06-01 DOI: 10.1016/j.heha.2023.100059
Judy S. LaKind , Carol J. Burns , Giffe T. Johnson , Sabine S. Lange

Epidemiology research plays an important role in regulatory risk assessments. However, regulatory approaches to evaluating study utility and quality for risk assessment purposes can vary, even within a single agency. The goal of the current review is to compare different guidelines within the US Environmental Protection Agency (US EPA) for evaluating epidemiology research with respect to quality. This review highlights the elements of epidemiology design and reporting that are most useful for risk assessment and regulatory decision making. General guidance documents from the US EPA that assess pesticides (Office of Pesticide Programs Framework), air pollutants (Integrated Science Assessment Preamble), and environmental chemicals (Integrated Risk Information System Handbook) were included. Chemical-specific examples of the use of these guidance documents were selected to provide additional information on each methodology. All three evaluation approaches require professional judgment, and none include a quantitative scoring approach. All indicate numerous aspects that enhance the value of a study for risk assessment. However, the methods and the level of detail vary. More clarity within US EPA documents would aid researchers. The elements of the Matrix tool, designed to facilitate translation of epidemiology studies to risk assessment, build on the US EPA epidemiology guidelines and may further enhance the value of such studies.

流行病学研究在监管风险评估中发挥着重要作用。然而,为风险评估目的而评估研究效用和质量的监管方法可能各不相同,即使在同一个机构内也是如此。本综述的目的是比较美国环境保护署(US EPA)在评价流行病学研究质量方面的不同指导方针。这篇综述强调了流行病学设计和报告中对风险评估和监管决策最有用的要素。包括美国环保署评估农药(农药计划框架办公室)、空气污染物(综合科学评估序言)和环境化学品(综合风险信息系统手册)的一般指导文件。选择了使用这些指导文件的特定化学品实例,以提供关于每种方法的额外信息。这三种评估方法都需要专业判断,没有一种包括定量评分方法。所有这些都表明了提高风险评估研究价值的许多方面。然而,方法和细节程度各不相同。美国环保署文件的更清晰将有助于研究人员。Matrix工具的要素旨在促进将流行病学研究转化为风险评估,以美国环境保护局流行病学指南为基础,并可能进一步提高此类研究的价值。
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引用次数: 0
期刊
Hygiene and environmental health advances
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